Patent application number | Description | Published |
20100010208 | PURIFICATION OF A TRIPLE HELIX FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE - Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix. | 01-14-2010 |
20100061979 | MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS WSITH IMPROVED BIOLOGICAL ACTIVITY - The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules. | 03-11-2010 |
20110027266 | Humanized anti-CXCR5 antibodies, derivatives thereof and their use - The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders. | 02-03-2011 |
20110150903 | FGF-R4 RECEPTOR-SPECIFIC ANTAGONISTS - The present invention relates to FGF-R4 receptor-specific antagonist molecules enabling the inhibition of the activity of said receptor. Said antagonists are, particularly, FGF-R4-specific antibodies enabling the inhibition of the activity of said receptor. The present invention also relates to the therapeutic use of said antibodies, particularly in the field of angiogenesis and in the treatment of certain types of cancer. | 06-23-2011 |
20120177639 | HUMANIZED ANTIBODIES SPECIFIC TO THE PROTOFIBRILLAR FORM OF THE BETA-AMYLOID PEPTIDE - The present application relates to humanized antibodies specific to the protofibrillar form of the beta-amyloid peptide, and to the use of said antibodies in the field of Alzheimer's disease. | 07-12-2012 |
20120195851 | MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS WITH IMPROVED BIOLOGICAL ACTIVITY - The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules. | 08-02-2012 |
20120244152 | NOVEL ANTAGONIST ANTIBODIES AND THEIR FAB FRAGMENTS AGAINST GPVI AND USES THEREOF - The present invention discloses novel antibodies that specifically bind to the human platelet membrane protein Glycoprotein VI (GPVI) and their monovalent fragments or derivatives. The antibodies of the invention are antibodies from hybridoma clone 390 and fragment antibodies thereof able to induce a GPVI depletion pheno-type. These antibodies and Fab fragments are able to block collagen binding and thus preventing platelet activation by collagen. The invention also relates to hybridoma clones and expression plasmids for the production of disclosed antibodies and Fab fragments. The present invention further refers to the uses of monovalent antibody fragments to manufacture research, diagnostic and immunotherapeutic agents for the treatment of thrombosis and other vascular diseases. The invention also concerns a Fab bearing a molecule at the C-terminal extremity, as well as method for prevention of recognition of Fab by antibodies using such modified Fab. The invention concerns a method for prevention of platelet activation when an anti-GP VI Fab is used. | 09-27-2012 |
20130039912 | ROBO1-FC FUSION PROTEIN AND USE THEREOF FOR TREATING TUMOURS - The present invention relates to a Robo1-Fc recombinant protein and to the use thereof for treating diseases in which a Slit protein is overexpressed, in particular cancer. The invention also relates to a composition including such a recombinant Another aspect of the invention involves using a Robo1-Fc molecule as a diagnostic tool for detecting the overexpression of a molecule belonging to the Slit family in a patient. | 02-14-2013 |
20130108641 | ANTI-GITR ANTIBODIES | 05-02-2013 |
20130156786 | PEPTIDE OR PEPTIDE COMPLEX BINDING TO 2 INTEGRIN AND METHODS AND USES INVOLVING THE SAME - The present invention relates to a peptide or peptide complex binding to α2 integrin, to one or more nucleic acid(s) coding for the peptide or peptide complex, a recombinant cell producing the peptide or peptide complex, a method for producing the peptide or peptide complex, a pharmaceutical composition comprising the peptide or peptide complex or the nucleic acid(s) for use as a medicament, a method for detecting α2 integrin and a screening method. | 06-20-2013 |
20130236476 | Humanized Anti-CXCR5 Antibodies, Derivatives Thereof And Their Use - The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders. | 09-12-2013 |
20130243783 | Humanized Anti-CXCR5 Antibodies, Derivatives Thereof And Their Use - The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders. | 09-19-2013 |
20130243793 | Humanized Anti-CXCR5 Antibodies, Derivatives Thereof And Their Use - The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders. | 09-19-2013 |
20130246035 | Humanized Anti-CXCR5 Antibodies, Derivatives Thereof And Their Use - The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders. | 09-19-2013 |
20130251714 | Humanized Anti-CXCR5 Antibodies, Derivatives Thereof And Their Use - The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders. | 09-26-2013 |
20140030265 | MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS METHOD - The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules. | 01-30-2014 |
20140046032 | METHOD OF PRODUCTION OF SIALYLATED ANTIBODIES - The present invention relates to a method for producing an IgG antibody, wherein at least 80% of the said antibody comprises a complex, bi-antennary oligosaccharide, which contains two sialic acid residues, attached to the Fc domain of the antibody. The said method comprises the steps of introducing a mutation in the Fc domain of the antibody, and expressing the mutant antibody in a cell which expresses a galactosyltransferase and a sialyltransferase activity. | 02-13-2014 |
20140105890 | HUMANIZED ANTIBODIES SPECIFIC TO THE PROTOFIBRILLAR FORM OF THE BETA-AMYLOID PEPTIDE - The present application relates to humanized antibodies specific to the protofibrillar form of the beta-amyloid peptide, and to the use of said antibodies in the field of Alzheimer's disease. | 04-17-2014 |
20150098939 | NOVEL ANTAGONIST ANTIBODIES AND THEIR FAB FRAGMENTS AGAINST GPVI AND USES THEREOF - The present invention discloses novel antibodies that specifically bind to the human platelet membrane protein Glycoprotein VI (GPVI) and their monovalent fragments or derivatives. The antibodies of the invention are antibodies from hybridoma clone 390 and fragment antibodies thereof able to induce a GPVI depletion phenotype. These antibodies and Fab fragments are able to block collagen binding and thus preventing platelet activation by collagen. The invention also relates to hybridoma clones and expression plasmids for the production of disclosed antibodies and Fab fragments. The present invention further refers to the uses of monovalent antibody fragments to manufacture research, diagnostic and immunotherapeutic agents for the treatment of thrombosis and other vascular diseases. The invention also concerns a Fab bearing a molecule at the C-terminal extremity, as well as method for prevention of recognition of Fab by antibodies using such modified Fab. The invention concerns a method for prevention of platelet activation when an anti-GP VI Fab is used. | 04-09-2015 |
20160108131 | ANTI-CEACAM5 ANTIBODIES AND USES THEREOF - The present invention discloses antibodies which bind human and | 04-21-2016 |
Patent application number | Description | Published |
20110153047 | Method and System for Making and Playing Soundtracks - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at pre-set start times in the soundtrack timeline. At at least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 06-23-2011 |
20140052283 | Method and System for Making and Playing Soundtracks - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 02-20-2014 |
20150347082 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20150347083 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20150347084 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20150348532 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20160085503 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 03-24-2016 |
Patent application number | Description | Published |
20140142954 | SOUNDTRACK FOR ELECTRONIC TEXT - A soundtrack creation method and user playback system for soundtracks synchronized to electronic text. Synchronization is achieved by maintaining a reading speed variable indicative of the user's reading speed. The system provides for multiple channels of audio to enable concurrent playback of two or more partially or entirely overlapping audio regions so as to create an audio output having, for example, sound effects, ambience, music or other audio features that are triggered to playback at specific portions in the electronic text to enhance the reading experience. | 05-22-2014 |
20140143642 | SOUNDTRACK FOR ELECTRONIC TEXT - A soundtrack creation method and user playback system for soundtracks synchronized to electronic text. Synchronization is achieved by maintaining a reading speed variable indicative of the user's reading speed. The system provides for multiple channels of audio to enable concurrent playback of two or more partially or entirely overlapping audio regions so as to create an audio output having, for example, sound effects, ambience, music or other audio features that are triggered to playback at specific portions in the electronic text to enhance the reading experience. | 05-22-2014 |
20140156046 | SOUNDTRACK FOR ELECTRONIC TEXT - A soundtrack creation method and user playback system for soundtracks synchronized to electronic text. Synchronization is achieved by maintaining a reading speed variable indicative of the user's reading speed. The system provides for multiple channels of audio to enable concurrent playback of two or more partially or entirely overlapping audio regions so as to create an audio output having, for example, sound effects, ambience, music or other audio features that are triggered to playback at specific portions in the electronic text to enhance the reading experience. | 06-05-2014 |
Patent application number | Description | Published |
20110153047 | Method and System for Making and Playing Soundtracks - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at pre-set start times in the soundtrack timeline. At at least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 06-23-2011 |
20140052283 | Method and System for Making and Playing Soundtracks - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 02-20-2014 |
20150347082 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20150347083 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20150347084 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20150348532 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 12-03-2015 |
20160085503 | METHOD AND SYSTEM FOR MAKING AND PLAYING SOUNDTRACKS - A composite variable duration soundtrack for a user to play while reading a text source, the soundtrack duration being defined by a soundtrack timeline. The soundtrack comprises multiple sound layers configured to play concurrently through the soundtrack timeline, each sound layer having an arrangement of one or more audio features that are configured to play at preset start times in the soundtrack timeline. At least one sound layer is adapted for modifying the preset start and stop times of its audio features to match the reading speed of a user based on a reading speed input. | 03-24-2016 |
Patent application number | Description | Published |
20140142954 | SOUNDTRACK FOR ELECTRONIC TEXT - A soundtrack creation method and user playback system for soundtracks synchronized to electronic text. Synchronization is achieved by maintaining a reading speed variable indicative of the user's reading speed. The system provides for multiple channels of audio to enable concurrent playback of two or more partially or entirely overlapping audio regions so as to create an audio output having, for example, sound effects, ambience, music or other audio features that are triggered to playback at specific portions in the electronic text to enhance the reading experience. | 05-22-2014 |
20140143642 | SOUNDTRACK FOR ELECTRONIC TEXT - A soundtrack creation method and user playback system for soundtracks synchronized to electronic text. Synchronization is achieved by maintaining a reading speed variable indicative of the user's reading speed. The system provides for multiple channels of audio to enable concurrent playback of two or more partially or entirely overlapping audio regions so as to create an audio output having, for example, sound effects, ambience, music or other audio features that are triggered to playback at specific portions in the electronic text to enhance the reading experience. | 05-22-2014 |
20140156046 | SOUNDTRACK FOR ELECTRONIC TEXT - A soundtrack creation method and user playback system for soundtracks synchronized to electronic text. Synchronization is achieved by maintaining a reading speed variable indicative of the user's reading speed. The system provides for multiple channels of audio to enable concurrent playback of two or more partially or entirely overlapping audio regions so as to create an audio output having, for example, sound effects, ambience, music or other audio features that are triggered to playback at specific portions in the electronic text to enhance the reading experience. | 06-05-2014 |
20150025663 | DELIVERY OF SYNCHRONISED SOUNDTRACKS FOR ELECTRONIC MEDIA CONTENT - A method and system for streaming a soundtrack from a server to a remote user device for a reader of electronic media content. The soundtrack is defined by multiple audio regions. Each audio region defined by an audio track for playback in the audio region, a start position in the electronic media content corresponding to where the playback of the audio region is to begin, and a stop position in the electronic media content corresponding to where the playback of the audio region is to cease. The streaming of the soundtrack is based on control data generated by the remote user device. | 01-22-2015 |
20150039991 | CREATION SYSTEM FOR PRODUCING SYNCHRONISED SOUNDTRACKS FOR ELECTRONIC MEDIA CONTENT - A method of creating, with a hardware system, a synchronised soundtrack for an item of electronic media content in which the playback of the soundtrack is synchronised with the user's reading speed. The method generates a graphical user interface (GUI) on a display comprising a reading display pane displaying at least a portion of the electronic media content in a reading format and a linear progression display pane displaying a linear progression of a range of reading position identifiers corresponding to at least a portion of the electronic media content displayed on the first display pane. User interaction with a GUI of the interface is used to configure audio data for each new audio region of the soundtrack. Both the reading display pane and linear progression display pane are simultaneously updated with graphical representations of the newly configured audio region showing an association between the audio region and the corresponding text region in the electronic media content to which it relates. | 02-05-2015 |
20150082136 | PLAYBACK SYSTEM FOR SYNCHRONISED SOUNDTRACKS FOR ELECTRONIC MEDIA CONTENT - A method for displaying electronic text and synchronizing the playback of a soundtrack for the electronic text. The soundtrack contains multiple audio regions configured for playback during corresponding text regions of the electronic text. Playback of the audio regions of the soundtrack over an audio output system is based on a reading position counter indicative of the user's estimate reading position, and which increments based on a user reading speed variable. The user reading speed variable is updated by processing eye tracking signals from an eye tracker to determine the user's reading scan rate. | 03-19-2015 |