Patent application number | Description | Published |
20110251568 | PUNCTAL PLUGS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS - Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured for controlled release into the eye by means of an osmotic engine. | 10-13-2011 |
20110301555 | POROUS MATRIX DRUG CORE FOR LACRIMAL INSERT DEVICE - Disclosed are novel structures and methods for drug cores containing therapeutic agents. Such cores may be inserted or manufactured in lacrimal insert devices for treating a variety of ocular conditions by eluding therapeutic agents according to a release profile determined by the structure and composition of the drug core. | 12-08-2011 |
20110311606 | PUNCTAL PLUGS WITH CONTINUOUS OR PULSATILE DRUG RELEASE MECHANISM - Disclosed are lacrimal inserts and their method of use for delivery of of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye. | 12-22-2011 |
20110311607 | PUNCTAL PLUGS WITH CONTINUOUS OR PULSATILE DRUG RELEASE MECHANISM - Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye. | 12-22-2011 |
20120059338 | PUNCTAL PLUG CONTAINING DRUG FORMULATION - Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye and is configured for release medication via a designated port, valve, or orifice in the insert housing and inhibits diffusion of medication via the housing itself. | 03-08-2012 |
20120197217 | PUNCTAL PLUGS WITH DIRECTIONAL RELEASE - Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid and includes means for directional release of medication into the lacrimal fluid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye. | 08-02-2012 |
20120283669 | PUNCTAL PLUGS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS - Lacrimal inserts such as punctal plugs may be utilized for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured for controlled, pulsatile release into the eye. | 11-08-2012 |
20130018360 | METHOD FOR DELIVERING OPHTHALMIC DRUGS - This invention relates to a method of delivering ophthalmic drugs, specifically prostaglandins and prostamides. This method may also be applied to other types of intraocular pressure (IOP)-lowering drugs (e.g. carbonic anhydrase inhibitors, beta blockers, alpha-adrenergic agonists, and parasympathomimetics) as well as other types of ophthalmic drugs for other indications (e.g. dry eye, inflammation, and infection). | 01-17-2013 |
20130184661 | EYE DRUG DELIVERY SYSTEM - A punctal plug or lacrimal insert comprising a microelectromechanical system pump and associated reservoir may be utilized to deliver precise dosages of an active agent into the eye though the tear film. The microelectromechanical system pump comprises four main components; namely, a reservoir, a pump, a series of valves and a vent. The microelectromechanical system pump is positioned within a cavity in the punctal plug. The microelectromechanical system pump is positioned with a cavity in the punctal plug. | 07-18-2013 |