Bradley, GB
Adrian Bradley, Bourne GB
Patent application number | Description | Published |
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20090063546 | Method and system for creating a data dictionary - A method is provided for creating a data dictionary. The method may include creating a first tier for the dictionary, the first tier including a descriptor name. The method may also include creating a second tier for the dictionary by creating a temporary term associated with the descriptor name; defining the temporary term using one or more attributes; checking, based on the attributes, a dictionary for an existing term with attributes that are the same as the attributes of the temporary term; associating, when the attributes are the same, the temporary term with the existing term in the second tier; and creating a new term in the second tier when the attributes are different. Further, the method may include creating a third tier for the dictionary, the third tier including process units for the attributes. | 03-05-2009 |
Allan Bradley, Cambridge GB
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20090069195 | COMPOSITIONS AND METHODS FOR ARRAY-BASED NUCLEIC ACID HYBRIDIZATION - The invention provides compositions and methods for generating a molecular profile of genomic DNA by hybridization of labeled nucleic acid representing the genomic DNA to immobilized nucleic acid probes, e.g., arrays or biochips. | 03-12-2009 |
20120167237 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 06-28-2012 |
20120204278 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 08-09-2012 |
20130042331 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 02-14-2013 |
20130263292 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 10-03-2013 |
20130263293 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 10-03-2013 |
20130318643 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 11-28-2013 |
20140041067 | ANTIBODIES, VARIABLE DOMAINS & CHAINS TAILORED FOR HUMAN USE - The invention relates to the provision of antibody therapeutics and prophylactics that are tailored specifically for human use. The present invention provides libraries, vertebrates and cells, such as transgenic mice or rats or transgenic mouse or rat cells. Furthermore, the invention relates to methods of using the vertebrates to isolate antibodies or nucleotide sequences encoding antibodies. Antibodies, heavy chains, polypeptides, nucleotide sequences, pharmaceutical compositions and uses are also provided by the invention. | 02-06-2014 |
20140120582 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-01-2014 |
20140134156 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-15-2014 |
20140150125 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-29-2014 |
20140150126 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-29-2014 |
20140182003 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 06-26-2014 |
20140201854 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 07-17-2014 |
20140201856 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 07-17-2014 |
20140283150 | Animal Models and Therapeutic Molecules - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 09-18-2014 |
20140323327 | ANIMALS, REPERTOIRES & METHODS - The present invention is directed to the concept of sectoring antibody gene segment repertoires in order to enable the development of novel, synthetic antibody chain repertoires not seen in nature. The present invention is also directed to the realisation of the inventors that sectoring can also alter gene segment expression by providing new arrangements of gene segment clusters relative to other gene segments and regulatory elements in transgenic immunoglobulin loci, thereby providing for new synthetic antibody chain sequence repertoires. The invention also relates to gene segment inversion. | 10-30-2014 |
20140325690 | Transgenic Non-Human Assay Vertebrates, Assays and Kits - The invention provides Assay Vertebrates comprising a human antigen or epitope knock-in for testing antibodies comprising human variable regions and generated in a related Antibody-Generating Vertebrate. The invention also provides kits and methods involving these vertebrates and antibodies. The invention provides for superior assay models and assay methods of chimaeric and other test antibodies comprising human variable regions. | 10-30-2014 |
20140331339 | Transgenic Non-Human Assay Vertebrates, Assays and Kits - The invention provides Assay Vertebrates comprising a human antigen or epitope knock-in for testing antibodies comprising human variable regions and generated in a related Antibody-Generating Vertebrate. The invention also provides kits and methods involving these vertebrates and antibodies. The invention provides for superior assay models and assay methods of chimaeric and other test antibodies comprising human variable regions. | 11-06-2014 |
20140331343 | ANTIBODIES, VARIABLE DOMAINS & CHAINS TAILORED FOR HUMAN USE - The invention relates to the provision of antibody therapeutics and prophylactics that are tailored specifically for human use. The present invention provides libraries, vertebrates and cells, such as transgenic mice or rats or transgenic mouse or rat cells. Furthermore, the invention relates to methods of using the vertebrates to isolate antibodies or nucleotide sequences encoding antibodies. Antibodies, heavy chains, polypeptides, nucleotide sequences, pharmaceutical compositions and uses are also provided by the invention. | 11-06-2014 |
20140359797 | Chimaeric Surrogate Light Chains (SLC) Comprising Human VpreB - The present invention relates inter alia to improvements in the production of chimaeric antibodies in non-human transgenic vertebrates such as mice and rats bearing one or more chimaeric antibody transgenes. In particular, the invention provides for improved non-human vertebrates and cells in which VpreB has been species-matched with the variable region of the chimaeric antibodies. Also, embodiments also provide for species-matching of the entire surrogate light chain for efficient pairing with chimaeric heavy chains during B-cell development in vivo in a non-human transgenic vertebrate setting. | 12-04-2014 |
20150033369 | ANIMALS, REPERTOIRES & METHODS - The present invention is directed to the concept of sectoring antibody gene segment repertoires in order to enable the development of novel, synthetic antibody chain repertoires not seen in nature. The present invention is also directed to the realisation of the inventors that sectoring can also alter gene segment expression by providing new arrangements of gene segment clusters relative to other gene segments and regulatory elements in transgenic immunoglobulin loci, thereby providing for new synthetic antibody chain sequence repertoires. The invention also relates to gene segment inversion. | 01-29-2015 |
20150033372 | Human VpreB & Chimaeric Surrogate Light Chains in Transgenic Non-Human Vertebrates - The present invention relates inter alia to improvements in the production of chimaeric antibodies in non-human transgenic vertebrates such as mice and rats bearing one or more chimaeric antibody transgenes. In particular, the invention provides for improved non-human vertebrates and cells in which VpreB has been species-matched with the variable region of the chimaeric antibodies. Also, embodiments also provide for species-matching of the entire surrogate light chain for efficient pairing with chimaeric heavy chains during B-cell development in vivo in a non-human transgenic vertebrate setting. | 01-29-2015 |
20150040250 | Animal Models and Therapeutic Molecules - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 02-05-2015 |
20150079680 | METHODS, CELLS & ORGANISMS - The invention relates to an approach for introducing one or more desired insertions and/or deletions of known sizes into one or more predefined locations in a nucleic acid (eg, in a cell or organism genome). They developed techniques to do this either in a sequential fashion or by inserting a discrete DNA fragment of defined size into the genome precisely in a predefined location or carrying out a discrete deletion of a defined size at a precise location. The technique is based on the observation that DNA single-stranded breaks are preferentially repaired through the HDR pathway, and this reduces the chances of indels (eg, produced by NHEJ) in the present invention and thus is more efficient than prior art techniques. The invention also provides sequential insertion and/or deletions using single- or double-stranded DNA cutting. | 03-19-2015 |
20150113669 | Animal Models and Therapeutic Molecules - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 04-23-2015 |
20150334998 | Animal Models and Therapeutic Molecules - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 11-26-2015 |
20160044900 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 02-18-2016 |
Allan Bradley, London GB
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20130209426 | METHOD FOR GENOME MODIFICATION - The present disclosure includes methods for manipulation of the genome, to products obtained or obtainable from such methods, and uses of these products. | 08-15-2013 |
Andrew Bradley, Coventry, Warwickshire GB
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20160059888 | System for a Towing Vehicle - The present invention relates to a vehicle control system ( | 03-03-2016 |
20160075281 | Vehicle Hitch Assistance System | 03-17-2016 |
Andrew Bradley, Coventry GB
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20160052548 | Vehicle Hitch Assistance System - The present invention relates to a system ( | 02-25-2016 |
Andrew J. Bradley, Glasgow GB
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20130013448 | BEHAVIORAL FILTER FOR PERSONALIZED RECOMMENDATIONS - This disclosure describes systems and associated methods that can selectively filter seed behavior, e.g., user activity used to generate item recommendations. In some embodiments, seed behaviors and catalog items are associated with categories in an electronic catalog, and a particular seed behavior is used to generate user recommendations if it is more recent than a user's last purchase in the category of the seed behavior. For example, a user's activity in the TV category, e.g., viewing various TV models, may not be used to generate recommendations if the activity occurred prior to the user's purchase of a TV. As a result, in certain embodiments, additional TVs may not appear in the user's recommendations following her purchase, reflecting that the user has fulfilled her desire to purchase a TV. | 01-10-2013 |
Austen Bradley, Daresbury GB
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20090038615 | BREATHING APPARATUS - A breathing apparatus and a method of reducing condensation within a breathing apparatus. The apparatus ( | 02-12-2009 |
Austin Bradley, Didcot GB
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20110198494 | MASS DISCRIMINATOR - An analysis device for mass discrimination is disclosed. The analysis device comprises: a sample chamber for holding a gaseous sample; an analysis chamber arranged to receive sample gas from the sample chamber; a mass discriminator arranged to discriminate in the analysis chamber between ion species generated from the sample gas; and a wall separating the sample chamber from the analysis chamber, the wall comprising a rupture zone controllable to rupture and thereby release sample gas from the sample chamber into the analysis chamber. In one embodiment the rupture zone is adapted to rupture on application of an electric current or mechanical force. The wall may be micromachined. A method of mass discrimination is also disclosed. | 08-18-2011 |
Daniel Marcus Bradley, Essex GB
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20080255144 | Acylated Piperidines as Glycine Transporter Inhibitors - The invention provides a compound of formula (I) or a salt or solvate thereof: | 10-16-2008 |
20080287547 | Glycine Transport Inhibitors - The present invention relates to compounds of formula (I), or to salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof. | 11-20-2008 |
20090270510 | GLYCINE TRANSPORT INHIBITORS - The present invention relates to compounds of formula (I), or salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof. | 10-29-2009 |
20100137276 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE - Compounds of formula (I), and salts and solvates thereof are provided: | 06-03-2010 |
20100216837 | GLYCINE TRANSPORT INHIBITORS - The present invention relates to compounds of formula (I), or salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof. | 08-26-2010 |
Daryl Wayne Bradley, Willingham GB
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20090049331 | Error propagation control within integrated circuits - A method of selecting where error detection circuits should be placed within an integrated circuit uses simulation of a reference and test design with errors injected into the test design and then fan out analysis performed upon those injected errors to identify error propagation characteristics. Thus, registers at which propagated errors are highly likely to manifest themselves or which protect key architectural state, or which protect state not otherwise protected can be identified and so an efficient deployment of error detection mechanisms achieved. Within an integrated circuit output signals from inactive circuit elements may be subject to isolation gating in dependence upon a detected current state of the integrated circuit. Thus, inactive circuit elements in which soft errors occur have inappropriate output signals gated from reaching the rest of the integrated circuit and thus reducing erroneous operation. | 02-19-2009 |
20090292977 | Error Detecting and Correcting Mechanism for a Register File - A data processing system includes a register file ( | 11-26-2009 |
Daryl Wayne Bradley, Cambridgeshire GB
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20090150722 | Recovering from errors in streaming dsp applications - A data processing system is provided in which processing circuitry performs at least one of a series of data processing operations in dependence upon a set of data values and control circuitry controls execution of the data processing operations. Control path error detection circuitry is provided for detecting a control path error associated with an error in operation of the control circuitry and data path error handling circuitry is arranged to handle recovery from errors in the data values. The control path error detection circuitry is configured to cause the data path error handling circuitry to perform recovery from detected control path errors enabling the series of data processing operations to continue despite the occurrence of the control path error. An associated method and computer program product are also provided. | 06-11-2009 |
20090177928 | Apparatus, Method and Computer Program Product for Generating Trace Data - A data processing apparatus is disclosed, said data processing apparatus comprising a plurality of devices, trace logic associated with at least one of said plurality of devices, and tagging logic associated with at least one of said plurality of devices, said tagging logic being operable to: select at least one item, said at least one item comprising an activity to be monitored; provide said at least one selected item with tag data identifying said at least one item as an item to be monitored; and said trace logic being operable to: detect tagged items processed by said at least one device; and output trace information relating to at least some of said detected tagged items. | 07-09-2009 |
20090254767 | Energy Management - A data processing apparatus and methods are disclosed. The data processing apparatus comprises: data processing elements operable to process data; an energy management unit operable to generate energy management information indicative of an energy state of at least one of the data processing elements when processing said data; and logic operable to receive said energy management information and to generate energy management information items associating said energy state with the processing of said data. The information items can provide visibility of how the Energy State of the data processing elements vary in response to the processing of data. Providing this visibility of the Energy State can advantageously enable more detailed the energy management to be performed and the Energy State of the data processing elements to be optimized. | 10-08-2009 |
Dennis Bradley, Stafford GB
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20090219147 | OBJECT DETECTION SYSTEM - There is provided an object detection system for a tractor ( | 09-03-2009 |
Donal Bradley, Seer Green GB
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20080278068 | Method of Patterning a Thin Film - A method of patterning a thin film, comprising: depositing an intermediate, radiation sensitive, layer on a substrate; depositing the thin film on the intermediate layer, before or after deposition of the thin film: exposing the intermediate layer to patterned radiation in order to initiate a chemical reaction therein; and removing patterned radiation-defined parts of the intermediate layer and corresponding thin film, to leave patterned thin film and patterned intermediate layer on the substrate. | 11-13-2008 |
Donal Bradley, Buckinghamshire GB
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20100219401 | Deposition of Organic Layers - A method for depositing one or more organic layers onto a substrate, which includes: transferring the one or more layers from a depositing surface of a stamp to the substrate by bringing the layer coated depositing surface of the stamp into contact with the substrate, and the use of either or both of the steps of: (i) contacting the polymer with a plasticizer; and (ii) heating the substrate and/or stamp, in order to create favorable conditions for conformal contact and uniform layer transfer. | 09-02-2010 |
Donal Bradley, Bucks GB
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20080277606 | Microfluidic Device - The invention relates to a microfluidic device comprising a zone for receiving a sample, an excitation source and a detector, wherein a portion of the zone allows transmission of energy at a required wavelength range and prevents transmission of energy at all other wavelengths and uses of the device in disposable on-chip fluorescent detection. | 11-13-2008 |
Donal Donat Conor Bradley, Buckinghamshire GB
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20100059755 | IMPROVED OXIDE-BASED FIELD-EFFECT TRANSISTORS - A field-effect transistor includes a source region; a drain region; a semiconductor layer disposed between the source and drain regions; a gate region; and a dielectric region disposed between the semiconductor layer and the gate region. The semiconductor layer comprises a titanium dioxide film. The transistor may be light sending, gas- or bio-sensing, or used in a visual display or in electronic circuits. The transistor is formed by forming a dielectric layer adjacent a gate region; forming a source region and a drain region; and forming a semiconductor layer on the dielectric layer, the semiconductor layer comprising titanium dioxide. The titanium dioxide semiconductor layer may be deposited by spray pyrolysis, or alternatively mesoporous TiO | 03-11-2010 |
20110095271 | HYBRID ORGANIC LIGHT EMITTING DEVICE - A hybrid organic light-emitting device comprises an anode, a cathode, respective adjacent hole and electron transport layers and an emissive layer therebetween. The electron transport layer comprises a metal oxide as a result of which the cathode may be formed of a transparent conductive oxide and the anode of a high work function metal. The metal oxide used for the electron injection layer may be ZrO | 04-28-2011 |
20110113859 | LOW-VOLTAGE THIN-FILM FIELD-EFFECT TRANSISTORS - A low-voltage thin-film field-effect transistor is formed by forming a gate, forming a dielectric layer on the surface of the gate, forming a source region and a drain region, and forming a semiconductor layer adjacent the dielectric layer. The dielectric layer is formed as a native oxide layer by oxidizing the surface of the gate. The semiconductor layer is deposited by spray pyrolysis. The dielectric layer may be functionalized with a self-assembling monolayer dielectric layer. The dielectric layer may be formed as a self-assembling monolayer, without first forming a native oxide (or other) dielectric layer. | 05-19-2011 |
20120058597 | FABRICATION METHOD FOR THIN-FILM FIELD-EFFECT TRANSISTORS - A thin-film field-effect transistor is formed by forming a dielectric layer adjacent a gate, forming a source region and a drain region, and forming a semiconductor layer on the dielectric layer. The semiconductor layer is deposited by spray pyrolysis and comprises a material selected from a group comprising: oxides; oxide-based materials; mixed oxides; metallic type oxides; group I-IV, II-VI, III-VI, IV-VI, V-VI and VIII-VI binary chalcogenides; and group I-II-VI, II-II-VI, II-III-VI, II-VI-VI and V-II-VI ternary chalcogenides. | 03-08-2012 |
Donal Donat Conor Bradley, London GB
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20100163808 | HIGHLY CONDUCTIVE AND STABLE TRANSPARENT CONDUCTING POLYMER FILMS - The invention relates to a process for the synthesis of conducting polymer films by vapour phase polymerization. The invention relates particularly to the synthesis of polymerized thiophene films, for example poly(3,4-ethylenedioxythiophene) (PEDOT) films. | 07-01-2010 |
Duncan James Bradley, Surrey GB
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20090101680 | SPRAY DISPENSER WITH COMPRESSED GAS CONTAINER - A dispenser ( | 04-23-2009 |
20120037157 | INHALER - An inhaler ( | 02-16-2012 |
Duncan James Bradley, Cranleigh GB
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20130340151 | BICYCLE HELMET WITH VENT - A bicycle helmet can include at least one ventilation opening and an exhaust port such that airflow enters the helmet through the ventilation opening and exits through the exhaust port, providing ventilation for a user. The orientation and location of the ventilation openings can reduce the aerodynamic drag of the helmet by delaying flow separation from the surface of the helmet and prevent airflow stagnation around the user's shoulders and neck. | 12-26-2013 |
Duncan James Bradley, Ewhurst GB
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20090007908 | Inhaler - An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises a spiral wound element within the housing that receives and coils said strip of blisters that have been breached. | 01-08-2009 |
Gabriel Bradley, Down GB
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20100277314 | ALARM APPARATUS - An apparatus ( | 11-04-2010 |
Ivor Bradley, Belfast GB
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20140115139 | Service Placement on Hosts for a Consumer Based on Their Geographic Location - Techniques are provided for service placement on hosts for a consumer based on geographic location The techniques include: determining a geographical location of a consumer; and inputting a topology model of an environment including multiple candidate hosts to support a service required by the consumer, the topology model including: a geographic location of each of resource in the environment; and connectivity details between the resources and between the resources and the consumer. The techniques also include: specifying bounding requirements for a host and/or bounding requirements for a path between the consumer to a host; calculating the distance from a candidate host to the consumer; determining if bounding requirements are met by a candidate host; and ordering candidate hosts that meet bounding requirements by distance. | 04-24-2014 |
Ivor G. Bradley, Belfast GB
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20140379881 | Network Device Configuration Management - Method and system are provided for network device configuration management. The method includes: receiving a set of user commands for configuration of a network device; retrieving a syntactic model of a network device configuration interface for a network device type and generating a modelled configuration of a current configuration of the network device; predicting the effect of the user command on the modelled configuration to generate a predicted modelled configuration; and applying rules for a user and/or network device type to determine if the command is permitted based on the predicted modelled configuration of the network device. Predicting the effect of the user command predicts in near real-time the effect on the network device configuration of a command that the user enters. | 12-25-2014 |
Jeremy Bradley, Bristol GB
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20120273995 | METHOD OF SEALING A GAP - A sealing unit for sealing a gap between a pair of surfaces includes a nozzle for injecting sealant into the gap, rollers, an endless track round the rollers, and a curing device. The sealing unit is moved along the length of the gap. A sealant is injected into the gap from the nozzle and the track is rotated around the rollers as they are moved along the length of the gap. The track is pressed onto first and second surfaces so the sealant in the gap is constrained by the track to lie substantially flush with the first and second surfaces. The sealing unit is moved along the length of the gap at a rate such that the sealant becomes sufficiently cured when it is in contact with the track so that the track can be peeled away from the sealant as the track rotates round the second roller. | 11-01-2012 |
20130037655 | METHOD OF SEALING A GAP - A method of sealing a gap between first and second aerodynamic surfaces. The width of the gap between the two surfaces is measured to obtain a gap measurement. The width of a seal member is pre-formed in accordance with the gap measurement. The seal member is fitted into the gap such that the seal member is substantially flush with the first and second aerodynamic surfaces. Apparatus for performing the method is also described. The apparatus comprising: a metrology device adapted to measure the width of the gap between the first and second aerodynamic surfaces; a seal member dispenser for dispensing a seal member; and a cutter adapted to cut the seal member to size in accordance with the measurements obtained by the metrology device. | 02-14-2013 |
20140339729 | METHOD OF SEALING A GAP - A sealing unit for sealing a gap between a pair of surfaces, the apparatus comprising a nozzle for injecting sealant into the gap; two or more rollers; an endless track which passes round the rollers; and a curing device for directing energy into the gap to initiate cure of the sealant. The sealing unit is moved along the length of the gap. A sealant is injected into the gap from the nozzle and the track is rotated around the rollers as they are moved along the length of the gap. The track is pressed onto the first and second surfaces so the sealant in the gap is constrained by the track to lie substantially flush with the first and second surfaces. Energy is directed into the sealant with the curing device, the curing energy initiating cure of the sealant. The sealing unit is moved along the length of the gap at a rate such that the sealant becomes sufficiently cured when it is in contact with the track so that the track can be peeled away from the sealant as the track rotates round the second roller. | 11-20-2014 |
Jeremy Peter Bradley, Bristol GB
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20100242996 | AIRCRAFT COMPONENT WITH AERODYNAMIC SURFACE COATING - An aircraft component with an aerodynamic surface coating comprising a resilient foam with an array of open cells infused with a cleaning material such as a gel, paste or liquid. This prevents contaminants such as insects from adhering to the aircraft component. The resilient foam stores at least part of the impact energy of the contaminant, the cleaning material is released from the deformed foam so that the cleaning material at least partially coats the contaminant, and the foam springs back to eject the coated contaminant from the aircraft component. | 09-30-2010 |
20100264274 | EDGE SEAL FOR FIBRE-REINFORCED COMPOSITE STRUCTURE - A fibre-reinforced composite structure includes a cut edge; an elastomeric cap covering the cut edge; and an adhesive sealant bonding the elastomeric cap to the cut edge. The fibre-reinforced composite structure is joined to a component and the elastomeric cap includes a generally Z or L-shaped cap with a web bonded to the cut edge of the fibre-reinforced structure and a flange bonded to the component and extending away from the fibre-reinforced structure. | 10-21-2010 |
John Stewart Bradley, Cottingham GB
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20090131248 | NOVEL NANOPOROUS MATERIALS - The invention provides a nanoporous non-oxide material which comprises a modified derivative of silicon nitride and comprises a plurality of nanoscale pores. The nanoporous non-oxide material is preferably prepared by means of a sol-gel procedure and preferably comprises a metal-containing derivative of silicon nitride [SiN | 05-21-2009 |
20100202939 | NOVEL NANOPOROUS MATERIALS - The invention provides a nanoporous non-oxide material which comprises a modified derivative of silicon nitride and comprises a plurality of nanoscale pores. The nanoporous non-oxide material is preferably prepared by means of a sol-gel procedure and preferably comprises a metal-containing derivative of silicon nitride [SiN | 08-12-2010 |
Joseph Bradley, Cookstown GB
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20090048719 | Environmental Temperature Control System - An environmental temperature control system comprises one or more thermostats ( | 02-19-2009 |
Kathryn Bradley, Hoddesdon GB
Patent application number | Description | Published |
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20140093564 | PHARMACEUTICAL COMPOSITIONS OF COMBINATIONS OF DIPEPTIDYL PEPTIDASE-4 INHIBITORS WITH SIMVASTATIN - The present invention is directed to novel pharmaceutical compositions comprising fixed dose combinations of a dipeptidyl peptidase-4 inhibitor (DPP-4 inhibitor), or a pharmaceutically acceptable salt thereof, and simvastatin, or pharmaceutically acceptable salt thereof, methods of preparing such pharmaceutical compositions, and methods of treating Type 2 diabetes and hypercholesterolemia with such pharmaceutical compositions. In particular, the invention is directed to pharmaceutical compositions comprising fixed-dose combinations of sitagliptin phosphate and simvastatin. | 04-03-2014 |
Lee Robert Bradley, Oxfordshire GB
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20150014364 | AEROSOL CONTAINER - An aerosol container ( | 01-15-2015 |
Louise Bradley, Glasgow GB
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20110008450 | Slow Release Compositions - The present invention relates to the provision of micron or sub-micron sized particles formed from one or more water-soluble crystals comprising a surface coating comprising one or more bioactive molecules wherein the particles are prepared such that in use the release of the bioactive molecule(s) is/are delayed and/or continually released over a period of time. Processes for the preparation of said particles, as well as the particles themselves are described, as well as uses of the particles. | 01-13-2011 |
Mark Bradley, Highfield GB
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20090190626 | Measurement of melting points of multiple samples - In a method of measuring a temperature value associated with melting, softening or decomposition of sample substances, an array of samples is deposited onto a support tray. The support tray is placed onto a heating device provided with temperature sensing means, the support tray is illuminated, and the array of samples is observed by a imaging device. WNle varying the temperature of the heating device, the image data from the imaging device is fed to an image recording device and temperature values associated with each feed of image data are also recorded. The image data is reviewed to detect changes in the image, such as image intensity, at each or selected sample locations, and the temperature of the heating device at an image change associated with a change in state of a sample is logged. Image processing software may be used to detect changes in the image, for example in the intensity of the image, at each sample location. The method may be used as a means for rapidly obtaining a melting point value for comparison of the physical characteristics of the members of a library of samples, especially polymer samples. | 07-30-2009 |
Mark Bradley, Edinburgh GB
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20090036322 | Leukocyte Adsorbing Material - A novel polyurethane material having excellent leukocyte adsorption capacity. When exposed to a labelled sugar chain solution LDF1 for 2 hours, it exhibits an adsorption amount of 400,000 or more. The polyurethane is composed of (A) a diisocyanate compound structural unit, (B) a polymer diol compound structural unit, and (C) a chain extender structural unit, preferably containing a tertiary amino group. | 02-05-2009 |
20090298915 | TOPICAL DRUG DELIVERY - Poly-pseudo-lysine conjugates have been shown to be able to penetrate into human skin and are proposed for both therapeutic and cosmetic treatments by topical application, e.g. change of skin pigmentation. | 12-03-2009 |
20100129550 | MODIFIED PIGMENTS - Pigments for inkjet inks are controllably functionalised to improve water-dispersibility, ozone resistance, etc., by irradiation of the pigment particle with high energy radiation, such as gamma radiation in air or by plasma activation, to form a stable functionalisable intermediate pigment particle, then activating the stable functionalisable intermediate, e.g. by heating, in the presence of a functionalising precursor (e.g. a polymer or polymerisable monomer) to form a modified pigment particle having one or more functionalising group grafted onto the pigment particle. | 05-27-2010 |
20100303890 | COPOLYMERS SUITABLE FOR USE IN CORNEAL BANDAGES - Disclosed is a polymer having an affinity for corneal cells such that it can be used as a substrate for the growth of corneal cells, and so is suitable for use in a corneal bandage, especially in the form of a contact lens in which at least the cornea contacting surface is composed of the polymer. The substrate with an affinity for corneal cells is a copolymer comprising units -(A)- and -(B)- in which the units A are derived from aminoalkyl (alkyl)acrylates and the units B are derived from aryloxy, alkoxy or hydroxyalkyl (alkyl)acrylates, and (alkyl)acrylic acids. | 12-02-2010 |
20100305198 | CATIONIC LIPIDS - This invention relates to cationic lipids. More particularly the invention relates to biodegradable cationic lipids having a plurality of cationic headgroups and one or more lipophilic tail groups. The lipids are of utility in various applications, and in particular in permitting transfection of molecules, and in particular DNA and RNA, into cells. As such the lipids have specific utility in the field of gene therapy as well as other applications such as delivery of small molecules into cells, detergents, and metal ion complexation for medical or industrial applications. | 12-02-2010 |
20110028337 | NUCLEOBASE CHARACTERISATION - The present invention provides modified nucleobase compounds, modified nucleic acid mimetic compounds and various uses thereof. In addition, the invention provides methods for nucleobase characterisation, SNP characterisation and nucleic acid sequencing. | 02-03-2011 |
20120003271 | POLYMER BLENDS - A biocompatible polymer mixture for use as a matrix for cellular attachment includes a mixture of at least two polymers selected from the group consisting of: chitosan (CS), polyethylenimine (PEI), poly(L-lactic acid) (PLLA), poly(D-lactic acid) (PDLA), poly(2-hydroxy ethyl methacrylate) (PHEMA), poly(ε-caprolactone) (PCL), poly(vinyl acetate) (PVAc), poly(ethylene oxide) (PEO), poly[(R)-3-hydroxybutyric acid)] (PHB), cellulose acetate (CA), poly(lactide-co-glycolide) (PLGA) and poly(N-isopropylacrylamide) (PNIPAM). Implants making use of the polymer mixtures can support cell attachment, growth and differentiation, and tissue regeneration in vivo. | 01-05-2012 |
20130065308 | CATIONIC LIPIDS - The invention provides a cationic lipid comprising: | 03-14-2013 |
20140134110 | OPTICAL IMAGING PROBES - The present invention relates to methods of visualising cells especially although not exclusively in vivo using a dye, such as a dendrimer-dye molecule or polybranched-dye molecule which is internalised by the cells and thus permits subsequent visualisation by confocal fluorescence endomicroscopy or other optical detectors. There is also provided internally quenched probes for use in visualising cells especially although not exclusively in vivo by confocal fluorescence endomicroscopy and the use of internally quenched probes in combination with confocal fluorescence endomicroscopy, for visualising cells by virtue of internalisation and dequenching of a probe by the cells. In a particular embodiment the cells are activated neutrophils, such as within the lung of a subject. | 05-15-2014 |
20140186945 | GROWTH OF CELLS - The present invention relates to the use of certain polymers as a substrate for stem cell, such as pluripotent stem cell growth and/or culture. The present invention also relates to articles such as tissue culture materials and cell culture devices comprising at least one polymer hydrogel as described herein. | 07-03-2014 |
20140315784 | Binding Inhibitors of the Beta. Transducin Repeat-Containing Protein - The present invention relates to compounds which bind to Beta Trans-ducin repeat-containing protein (PTrCP), and modulate the activity of 13TrCP. In particular, the invention relates to compounds which demonstrate optimised binding to PTrCP. The invention also relates to pharmaceutical compositions comprising such compounds and the use of such compounds as medicaments, specifically for the treatment of disorders associated with aberrant protein degradation, such as cancer. The preferred binding inhibitors are peptides derived from the motive DSGXXS, e.g. DEGFWE, DDGFWD and Succinyl-EGFWE. | 10-23-2014 |
20140329715 | Water Treatment and Monitoring - The present invention relates to the provision of polymers that are selected to have either; surface properties that allow protozoa, in particular | 11-06-2014 |
Michael Bradley, Kent GB
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20100200300 | ELECTROMAGNETIC TREATMENT OF CONTAMINATED MATERIALS - A method for separating a hydrocarbon content from a hydrocarbon contaminated matrix is disclosed. The method comprises controlling a water content of a feed material comprising the hydrocarbon contaminated matrix; continuously conveying the feed material into a treatment cavity ( | 08-12-2010 |
Michelle Bradley, Horsham GB
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20120183549 | CHEMOKINE RECEPTOR BINDING POLYPEPTIDES - The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2. | 07-19-2012 |
20130330346 | Chemokine receptor binding polypeptides - The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2. | 12-12-2013 |
20140050736 | CHEMOKINE RECEPTOR BINDING POLYPEPTIDES - The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2. | 02-20-2014 |
Neil Bradley, Newcastle Upon Tyne GB
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20140053877 | DISHWASHING METHOD - An automatic dishwashing liquor comprising: | 02-27-2014 |
20140053878 | DISHWASHING METHOD - An automatic dishwashing liquor comprising: | 02-27-2014 |
20150203797 | DETERGENT COMPOSITIONS - A method for treating textiles having oily soils wherein textiles are contacted with an aqueous solution comprising brightener and optionally, alklyphthalimide derivatives and mixtures thereof, and then rinsed and dried. | 07-23-2015 |
20150203798 | DETERGENT COMPOSITIONS - A composition and method for treating textiles wherein textiles are contacted with a composition comprising optical brightener and fabric shading dyes optionally with alklyphthalimide derivatives and mixtures thereof. | 07-23-2015 |
Nick Bradley, Melksham Wiltshire GB
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20120120234 | PLATFORM SCREEN DOOR - A platform screen door system, comprising a fixed panel, a door leaf slidably disposed adjacent to the fixed panel, a drive means adapted to slidingly move the door leaf from a door open position to a door closed position; and a microprocessor adapted to control the movement of the drive means and, thereby, control the movement of the door leaf The system also includes a media panel, disposed on the fixed panel, wherein the media panel is adapted to display information. | 05-17-2012 |
Nigel Bradley, Cricklade GB
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20130095833 | DEACTIVATING PACKET DATA PROTOCOL CONTEXT - A method is provided of deactivating PDP Context upon transfer of a connection with a user terminal between a femtocell base station and a macrocell base station, the method comprising: the femto base station receiving a message including a first identifier of a PDP Context, altering the identifier of a PDP Context to a second identifier, and forwarding the altered message to the core network, the core network receiving a message including an identifier determines that the received identifier does not match the identifier that it expects and so deactivates the PDP Context. | 04-18-2013 |
Nigel Bradley, Wiltshire GB
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20100150109 | METHOD OF IDENTIFICATION OF A FEMTOCELL BASE STATION AS A HANDOVER TARGET, AND APPARATUS THEREFOR - A method is provided of identifying which one of a plurality of femtocell base stations neighbouring a first femtocell base station is to be the target for handover of a call connection with a user terminal from the first base station. The neighbour femtocell base stations use the same primary scrambling code as each other. The femtocell base stations use code-division multiple access, CDMA. Each of the neighbour femtocell base stations transmits a respective broadcast signal that include timing information such that each neighbour femtocell base station transmits a broadcast signal having different timing information to that of the other neighbour femtocell base stations. The user terminal receives broadcast signals, determines the timing information of at least one of the received broadcast signals and reports the timing information to the first femtocell base station. The first femtocell base station identifies the target femtocell base station for handover from the timing information. | 06-17-2010 |
20120165005 | FEMTOCELL ARRANGEMENTS - A femtocell arrangement comprises a plurality of femtocells Femto 1 to Femto 13 having coverage distributed over a region, such as, for example, an office. A border femtocell, Femto 3 or Femto 10, of said plurality has coverage at an entrance to the region and is arranged to operate at a higher transmit power level to provide a larger coverage area than that provided by neighboring femtocells. In addition, the border femtocell may be allocated a specific Primary Scrambling Code (PSC) to show its designation as a border femtocell. An approaching user equipment UE 1 or UE 2 tends to attach to the higher transmit power border femtocells. The Femto Gateway managing the connection is aware of the likelihood that an approaching UE will tend to attach to a border femtocell, and this is further confirmed by the use of a specific PSC. Hence, handover is expedited as the most suitable femtocells may be chosen as targets for handover. | 06-28-2012 |
Nigel Paul Thoresby Bradley, Nottingham GB
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20100089810 | Water Filtration Apparatus - A water filtration apparatus has at least one tank in fluid communication with a conduit through at least one aperture in a wall. Each tank uses filter blocks to support the filter medium and to direct the filtered water to the conduit via the aperture. An end plate for the filter block is provided, the end plate being adapted to seal against a free end of the filter block. The end plate also provides apertures for fluid flow into and out of the filter block, and a device for receiving a sealant to provide a seal between the end plate and the wall. The end plate improves the installation of the apparatus, and the sealant improves the reliability of the seal round the apertures, which in turn improves the efficiency of a backwash operation used to clean the filter medium. | 04-15-2010 |
Oliver James Bradley, Surrey GB
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20090327398 | Method and System for User Equipment Configuration - A method of managing configuration of user equipment that has a configuration database modifiable with configuration data in a first format, and a communications unit for receiving configuration data in a second format is described. The method comprises storing a user agent at the user equipment; providing received configuration data in the second format to the user agent; using the user agent to transform the configuration data into the first format in the user equipment; and modifying the configuration database with the configuration data in the first format. | 12-31-2009 |
Paul Bradley, Fareham Hampshire GB
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20100015949 | METHOD AND DEVICE TO USE A MOBILE TERMINAL WITH A NEW SUBSCRIPTION - The invention relates to a method and device to use a locked mobile terminal with a new subscription. This method is based on presentation of several IMSI and detection of an IMSI with valid MCC and/or MNC code replaced by another IMSI so that the end-user can use his new SIM card with the locked mobile terminal. | 01-21-2010 |
Paul Anthony Bradley, Sandwich GB
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20090099209 | Compounds Useful in Therapy - Compounds of formula (I), | 04-16-2009 |
Paul C. Bradley, Stock On Tees GB
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20110041726 | TITANIUM DIOXIDE - A coloured composition comprising: a) NIR scattering TiO | 02-24-2011 |
Paul C. Bradley, Ingleby Barwick GB
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20150329737 | TITANIUM DIOXIDE - A coloured composition comprising: a) NIR scattering TiO | 11-19-2015 |
Paul Michael Bradley, Cambridge GB
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20120178112 | METHOD OF DETECTING SKELETAL MUSCLE DAMAGE - The present invention relates to a method of detecting skeletal muscle damage and to the use of certain proteins and fragments thereof as biological markers (commonly known as “biomarkers”) for such damage. The present invention has particular reference to the detection of muscle toxicity in mammals, particularly humans. | 07-12-2012 |
Philip Bradley, Birmingham GB
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20100270070 | ISOLATION - An apparatus and method is provided for isolating a telecommunication device by introducing the device to a first container part of a container, the container having a first container part and a second container part, the first container part being accessed from the second container part through a first seal, the first seal having an open state and a closed state, the second container part being accessed from the environment around the container through a second seal, the second seal having an open state and a closed state. The first container part and second container part, at least in part are formed of a flexible electrical conductor to provide electromagnetic shielding. The method includes the device being introduced to the first container part of the container with the first seal and the second seal in the open state, one or both of the first and second seals then being placed in the closed state to isolate the device from external electromagnetic radiation. | 10-28-2010 |
Robert David Bradley, Berkshire GB
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20150329736 | OPACIFYING POLYMER PARTICLES - An aqueous dispersion of pigmented opacifying polymer particles, the particles comprising: i. an inorganic core comprising dispersed inorganic pigment particle and a dispersant ii. a first layer of base-swellable polymer comprising acid groups encapsulating the core iii. a second layer of non-base-swellable polymer encapsulating the first layer wherein the dispersant comprises or consists of hydroxyl moieties; and carboxyl groups derived from itaconic acid. | 11-19-2015 |
Robert David Bradley, Reading Berkshire GB
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20150315408 | A METHOD OF MAKING OPACIFYING POLYMER PARTICLES - A method of preparing an aqueous dispersion of opacifying polymer particles containing inorganic pigment particles therein comprising or consisting of the steps of: i. dispersing inorganic pigment in aqueous medium using a dispersant of acid value at least 65 mg KOH/g of dispersant, the dispersant comprising acid moieties and the pH during dispersion is greater than the pKa of the acid moieties and also at least 0.25 pH units above or below the iso-electric point of the pigment particles, to form a stable aqueous dispersion of the pigment in the aqueous medium ii. adjusting the pH of the pigment dispersion to below the pKa of the acid moieties comprising the base swellable polymer of step iii. whilst satisfying the pH criteria of step i. iii. forming a first layer of a base swellable polymer on the pigment particles by polymerising monomers comprising acid moieties iv. forming a second layer of non-base swellable polymer v. optionally polymerising further monomers to form intermediate polymer layers having acid value between 0 and 65 mg KOH/g polymer between the pigment and the first layer and/or between the first and second layer vi. at least partially neutralising the base-swellable-polymer, using a base, at a temperature above the effective Tg of the non-base-swellable polymer whereby the base-swellable polymer is caused to swell vii. and cooling the dispersion of opacifying polymer particles to a temperature below the effective Tg of the non-base-swellable polymer. | 11-05-2015 |
Robert Harold Bradley, Aberdeen GB
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20100024643 | COATING PROCESS AND COATED PRODUCT - A process modifies the surface diffusion and wetting characteristics of a microporous material such as active carbon or silica, by applying a plasma of polymer precursor monomers to an external surface of the material to modify its adsorption properties, the microporous material obtainable thereby being modified by presence of a nanolayer of polymeric material extending over said external surface around the pores to partially occlude pore openings to a predetermined extent, but the nanolayer does not substantially infiltrate the pores of the microporous material. | 02-04-2010 |
Robert J. Bradley, Nottingham GB
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20100071181 | Tooling - An expander for concentrically expanding a cylindrical member, the expander with a tapered block, a plurality of segments, each having an inner surface at least partially in contact with the tapered surface of the tapered block and the segments arranged to move in concert with each other relative to the block, and a pair of engaging features being provided for each segment, each pair comprising a first engagement feature on one of the segments and a second engagement feature on the block, the pairs of engaging features being arranged to maintain equal circumferential spacing of the segments around the block and to constrain movement of the segments in a direction that is coaxial with the block, each pair of engaging features being located away from the circumferential edges of their respective segment. | 03-25-2010 |
Ross Bradley, Wiltshire GB
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20090145325 | PLATFORM SCREEN DOORS - An apparatus and method for controlling the operation of a screen door system. The apparatus includes a first transceiver adapted to be mounted on a train, a second transceiver adapted to be mounted on either a train platform or a portion of the platform screen door system. The first and second transceivers are configured to communicate with each other such that when a train is stopped at the train platform within a predetermined distance of and adjacent to a door of the platform screen door system, a signal is transmitted from the first transceiver to the second transceiver to open the door. When passenger embarkation and debarkation is complete, a signal is transmitted from the first transceiver to the second transceiver to close the door, and when the door is closed and locked, a signal is transmitted to the train to depart. | 06-11-2009 |
20100295366 | BRAKE SYSTEM - A brake system for a railway vehicle having wheel slide protection includes a main brake pipe fluidly connected to a distributor, and an auxiliary reservoir fluidly connected to the brake distributor, the distributor being fluidly connected to one or more brake cylinders. A further reservoir is provided, compressed air flow to and from the further reservoir being controllable by a valve, operation of the valve being controlled by a control unit adapted to detect wheel slide. The control unit is adapted to switch air supply between air from the auxiliary reservoir and air from the further reservoir in the event that wheel slide is detected. | 11-25-2010 |
Ross Bradley, Melksham GB
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20140257604 | BRAKING SYSTEM - A brake control unit for a railway vehicle having first and second cores. The first core is responsible for brake control functions and the second core is responsible for communications. A switch controls communication between the second core and a communication bus on the railway vehicle to safeguard the braking function of the first core. The second core only has write access to the communication bus when enabled by the first core, which first core determines whether the system is in a defined safe state to safeguard the braking function. This reduces the testing requirements for new communications software. | 09-11-2014 |
20150307071 | EMERGENCY BRAKING - A brake system for a railway vehicle comprises a service brake with control valves and an emergency brake with a emergency brake valve adapted to permit or prevent emergency brake pressure from reaching the service brake control valves. The emergency brake is actuatable by a signal on an emergency brake wire. The brake system further comprises an isolating circuit adapted to permit or prevent control of the service brake control valves. | 10-29-2015 |
Ross Bradley, Melksham Wiltshire GB
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20120120234 | PLATFORM SCREEN DOOR - A platform screen door system, comprising a fixed panel, a door leaf slidably disposed adjacent to the fixed panel, a drive means adapted to slidingly move the door leaf from a door open position to a door closed position; and a microprocessor adapted to control the movement of the drive means and, thereby, control the movement of the door leaf The system also includes a media panel, disposed on the fixed panel, wherein the media panel is adapted to display information. | 05-17-2012 |
Scott Bradley, Leslie GB
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20110109642 | METHOD OF COMPOSITING VARIABLE ALPHA FILLS SUPPORTING GROUP OPACITY - A method of compositing a plurality of graphic objects with a compositing buffer, is disclosed. The plurality of graphic objects forming a group is attenuated by group opacity and is composited from a top object to a bottom object. Based on a first mask and the group opacity, a second mask is generated. The first mask stores a remaining possible contribution for further graphic objects below and including the plurality of graphic objects. The plurality of graphic objects in a top down order is processed. In particular, for each graphic object of the plurality of graphic objects: (a) a contribution value for the graphic object using the second mask is determined, the contribution value representing a contribution of the graphic object to the compositing buffer; (b) a colour value of the graphic object is composited with the compositing buffer using the contribution value; and (c) the second mask is updated using the contribution value. The first mask is then updated using the second mask and the group opacity. The updated first mask is configured for further compositing of objects below the plurality of graphic objects. | 05-12-2011 |
Steven Bradley, London GB
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20160127348 | LINKED REGISTRATION - Secure registration of a new application with a server system is provided. An old application has been registered with the system. A first link between the new application and the system establishes a first key and first check data is communicated from the system to the new application and passed to the old application. A second link between the old application and the system establishes a second key based on input of a credential to the old application; the first check data is communicated from the old application to the system. Enciphered second check data is communicated from the system to the old application over the second link and further encrypted by the old application using a third key. This generates doubly-enciphered check data which is passed to the new application and decrypted using the first key and a fourth key, generated at the new application based on the first check data and input of the credential to the new application. | 05-05-2016 |
Steven Bradley, Knutsford GB
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20140122344 | Secure Computing Environment - A portable electronic device having a memory storing application software for initiating a payment transaction with a remote system, a data interface for coupling the device to a host computer, a contactless interface for receiving payment token data from a contactless payment token, and a cellular network interface for communication of data over a cellular network. The application software is executed from the device when the device is connected to the host computer and configures the portable electronic device to initiate a payment transaction by receiving payment token data via the contactless interface means and transmitting said payment token data to the remote system via the mobile network interface means. | 05-01-2014 |
20140122901 | Device and Method For Secure Memory Access - In a secure computing environment, a method, system and device are provided for loading stored encryption key data from a protected non-volatile memory of a portable device. A boot loader program is initiated after the portable device is powered on, encryption key data is loaded from the protected non-volatile memory of the portable device, and access to the protected non-volatile memory is disabled after a predetermined time after the portable device is powered on. In this way, the encryption key data is loaded from the protected non-volatile memory of a portable device before the boot operating system is loaded. | 05-01-2014 |
Stuart Bradley, Lutterworth Leicestershire GB
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20140139069 | Axial flux machine - An axial flux machine comprising a rotor mounted about an axis of rotation and having two axial faces. A first stator ring is positioned on the rotor adjacent to a first axial face, to define an air gap, between the first stator ring and first axial face. The first stator ring is formed by stator ring segments, each having a radially inner and outer edge. A second stator ring is positioned on another side of the rotor, adjacent to the second axial face, to define an air gap between the second stator ring and second axial face. The second stator ring is, also, formed by stator ring segments, each having a radially inner and outer edge and corresponding to a first stator ring segment. The stator ring segments are deflectable in unison in response to axial deflection of the rotor, to maintain the air gaps, due to link elements. | 05-22-2014 |
Stuart Bradley, Lutterworth GB
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20140132109 | ROTATING ELECTRICAL MACHINE HAVING A SEGMENTED STATOR - A rotating electrical machine comprises a rotor having an axis of rotation and a stator assembly surrounding the rotor. The stator assembly comprises a plurality of circumferentially arranged stator segments and a plurality of link elements of which at least one link element extends between each of the circumferentially adjacent stator segments. Each link element provides a rigid circumferential connection between circumferentially adjacent stator segments so that the linked stator segments form a torsionally stiff annular stator and also provides a radially flexible connection between circumferentially adjacent stator segments to permit relative movement between adjacent linked stator segments in the radial direction. | 05-15-2014 |
Stuart Bradley, Warwickshire GB
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20150321740 | CYCLOIDAL MARINE-PROPULSION SYSTEM - A cycloidal marine-propulsion system is disclosed. The system comprises a blade-mounting disc and a plurality of propeller blades. Each of the plurality of propeller blades has a respective primary blade axis and is connected to the disc in a manner allowing the blade to be rotated about its primary blade axis independent of any about-axis rotation of every other one of the propeller blades. The system also includes a plurality of electric actuators, each actuator being connected to a respective one of the propeller blades. The system further includes a controller in communication with the electric actuators for controlling selectively each of the electric actuators. | 11-12-2015 |
Stuart Edward Bradley, Oxfordshire GB
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20100173886 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS - Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity. | 07-08-2010 |
20100286112 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS - The present invention is directed to therapeutic compounds which have dual activity as agonists of GPR119 and inhibitors of DPP-IV and are useful for the treatment of metabolic disorders including type II diabetes. | 11-11-2010 |
Stuart Ian Bradley, Leicester GB
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20100059878 | Stack Assemblies Containing Semiconductor Devices - The present invention provides a stack assembly comprising at least one semiconductor device | 03-11-2010 |
20100225121 | Rotating Electrical Machines - A torsional vibration damper is integrated into a rotating electrical machine. A rotatable assembly of the electrical machine includes a rotor core pack having a first end and a second end. The integrated torsional vibration damper consists of a torsional elastic coupling and a torsional elastic damper and provides mechanical damping. The integrated torsional vibration damper is mounted to the rotatable shaft of the electrical machine by a flange. The rotor core pack is mounted at the first end to the integrated torsional vibration damper by suitable structure members such as a mounting flange and is not fixedly mounted directly to the rotatable shaft. In the case where the rotor core pack is cooled by circulating coolant fluid (e.g. MIDEL) then the integrated torsional vibration damper may be a viscous damper that uses the coolant fluid as a viscous working fluid. | 09-09-2010 |
20130057092 | ROTORS FOR ELECTRICAL MACHINES - The present invention relates a rotor assembly for an electrical machine (e.g. motor or generator) where a tuned vibration absorber adapted to provide radial damping is mounted directly to the rotor shaft. | 03-07-2013 |
20130099608 | ROTATING ELECTRICAL MACHINES - A torsional vibration damper is integrated into a rotating electrical machine. A rotatable assembly of the electrical machine includes a rotor core pack having a first end and a second end, The integrated torsional vibration damper consists of a torsional elastic coupling and a torsional elastic damper and provides mechanical damping. The integrated torsional vibration damper is mounted to the rotatable shaft of the electrical machine by a flange. The rotor core pack is mounted at the first end to the integrated torsional vibration damper by suitable structure members such as a mounting flange and is not fixedly mounted directly to the rotatable shaft. In the case where the rotor core pack is cooled by circulating coolant fluid (e.g. MIDEL) then the integrated torsional vibration damper may be a viscous damper that uses the coolant fluid as a viscous working, fluid. | 04-25-2013 |
Stuart Ian Bradley, Lutterworth GB
Patent application number | Description | Published |
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20150032392 | CONDITION MONITORING OF ANTI-VIBRATION MOUNTS - Monitoring the condition of an anti-vibration mount, e.g. a sandwich mount in which a plurality of elastomeric layers are interleaved with rigid plates. A set of effectiveness data is determined using input and output data measured or derived over a period of time. The effectiveness data is indicative of the effectiveness of the anti-vibration mount, in particular is dynamic stiffness. The input data is indicative of the amplitude of input vibrations that are applied to the anti-vibration mount and the output data is indicative of the amplitude of corresponding output vibrations of the anti-vibration mount (e.g. the vibrations that are transferred into an external support frame of the associated apparatus or equipment). The operating condition of the anti-vibration mount is monitored using the set of effectiveness data, e.g. by comparing successive sets of effectiveness data determined using input and output data collected over different time periods. | 01-29-2015 |
Stuart Ian Bradley, Leicestershire GB
Patent application number | Description | Published |
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20120169156 | Suspension Structures - A support structure is used to mount the stator of a rotating electrical machine (e.g. a motor or generator). The support structure includes a rigid external support frame ( | 07-05-2012 |
20130020893 | Electrical Machines - An electrical machine | 01-24-2013 |
20130043756 | RETAINING BANDS - The present invention relates to a retaining band which provides outer reinforcement for the rotor assembly of a high speed electrical machine. The rotor assembly includes a plurality of circumferentially-spaced permanent magnet assemblies. A retaining band is fitted around the rotor assembly and applies a pre-load to the permanent magnet assemblies in the radial direction. The retaining band has a plurality of voids that are sized and shaped to provide the retaining band with a progressive spring stiffness in the radial direction. The voids are open before the retaining band is fitted and during the fitting process the retaining band is deflected in the radial direction so that the voids close up and the retaining band becomes substantially solid. | 02-21-2013 |
20150303760 | GEARLESS DRIVE FOR A ROTATING ELECTRICAL MACHINE - A gearless drive for a rotating electrical machine comprises a rotor in the form of a hollow rotatable body and having an axis of rotation and a stator surrounding the rotor. A plurality of pole bodies are independently mounted circumferentially around the rotor by a pole mounting arrangement. The stiffness of the pole mounting arrangement in the radial direction is greater than the stiffness of the pole mounting arrangement in the circumferential direction. | 10-22-2015 |
Tim Bradley, West Midlands GB
Patent application number | Description | Published |
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20090090651 | CRAFT BOARD - The invention provides a craft board comprising a base and a cover. The board also comprises a plurality of hinge locations about which the base and cover can rotate relative to each other and selectively engageable hinge means arranged to allow engagement and disengagement between the base and the cover at the plurality of hinge locations. | 04-09-2009 |
William James Bradley, Cambridgeshire GB
Patent application number | Description | Published |
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20100045463 | Method and apparatus for real time performance assessment - An apparatus for monitoring performance comprises two elements: a first element ( | 02-25-2010 |
20140364980 | METHOD AND APPARATUS FOR REAL TIME PERFORMANCE ASSESSMENT - An apparatus for monitoring performance comprises two elements: a first element ( | 12-11-2014 |