Patent application number | Description | Published |
20120024405 | GUIDING DEVICES AND METHODS OF MAKING AND USING THE SAME - A fluid connector device is provided. The fluid connector device comprises a coupling substrate comprising a conformal recess, a reconnectable fitting corresponding to the conformal recess, and a guiding device. The guiding device comprises a base component, a body at least partly disposed in the base component and comprising a broad end and a narrow end, wherein the broad end is disposed away from the coupling substrate, and wherein the body is slidably disposed in the base component, and a resilient component disposed on the body of the guiding device and configured to move the reconnectable fitting one or more degrees in a translational, or a rotational direction, or both, relative to the coupling substrate. The fluid connector device further comprises a force applying element operatively coupled to the guiding device, the coupling substrate, or both, to at least partially provide a sealing force between the reconnectable fitting and the coupling substrate, wherein at least one of the force applying element, the reconnectable fitting, and the coupling substrate are adapted to move one or more degrees to enable self-alignment between the reconnectable fitting and the conformal recess. | 02-02-2012 |
20120027648 | INTERFACING CAPS FOR MICROFLUIDIC DEVICES AND METHODS OF MAKING AND USING THE SAME - An interfacing cap for a reagent storage vessel is provided. The interfacing cap comprises a partitioning element having a structure corresponding to an opening of the reagent storage vessel, a projection fitting disposed on the partitioning element, a holder element, and a puncturing element coupled to the projection fitting. | 02-02-2012 |
20130004414 | DEVICES AND METHODS FOR REDUCING RADIOLYSIS OF RADIOISOTOPES - Disclosed are microfluidic devices and kits for containing radioisotopes. The devices and kits comprises at least one confining geometry having a cross-section dimension below the beta(+) or beta(−) range of a radioisotope, when containing the radioisotope configured in such a way that that neighboring segments of the confining geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the segments when containing the radioisotope. Methods of storage and synthesis of radiopharmaceuticals are also disclosed. In another aspect, the present invention relates to methods of storing radiotracers and synthesizing radiopharmaceuticals, using the aforementioned device. The radiotracers and radiopharmaceuticals comprises | 01-03-2013 |
20130005958 | DEVICES AND METHODS FOR REDUCING RADIOLYSIS OF RADIOISOTOPES - Disclosed are devices and methods for reducing radiolysis of radiopharmaceuticals during filtration, concentration and purification. The devices comprises two or more confining geometry having a cross-section dimension below the beta(+) or beta(−) range of the radioisotope in use, when containing the radioisotope, and configured in such a way that neighboring geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the confining geometries when containing the radioisotope. Methods of filtration of radioisotope containing mixtures are also disclosed. | 01-03-2013 |
20130053994 | METHOD AND APPARATUS FOR MONITORING RADIOPHARMACEUTICAL PROCESSING - System and method for monitoring a synthesis process in a synthesizer to provide reduced quality control efforts and facilitate quality by design. The system and method perform by detecting a synthesizer parameter value for one or more synthesizer parameters of a radiopharmaceutical synthesis process in a radiopharmaceutical synthesizer, and comparing the synthesizer parameter value of each of the synthesizer parameters to a corresponding reference synthesizer value range. The radiopharmaceutical synthesis process is either continued, aborted, or interrupted based on a comparison result. | 02-28-2013 |
20130108513 | MICROFLUIDIC CHIP AND A RELATED METHOD THEREOF | 05-02-2013 |
20130170931 | MICROFLUIDIC HANDLING SYSTEM - Techniques and devices are provided related to a handling system for cassettes for radiolabeled compound synthesis that include a magazine that is unshielded and that is configured to receive a plurality of microfluidic synthesis cassettes. In one embodiment, the plurality of microfluidic synthesis cassettes include nonradioactive reagents to generate a radiolabeled compound when reacted with a radioactive species. In this manner, a cassette handling device may be stored unshielded and may be coupled to a cassette handling platform to allow advancement of the plurality of microfluidic synthesis cassettes into the cassette handling platform and, in turn, a shielded radiosynthesis machine. | 07-04-2013 |
20130255789 | MICROFLUIDIC DEVICE AND A RELATED METHOD THEREOF - A microfluidic device includes a plurality of reagent sources for a feeding a plurality of reagents, each reagent source feeding a corresponding reagent among the plurality of reagents. A macro-chamber receives one or more reagents among the plurality of reagents from the plurality of reagent sources. A microfluidic reactor is coupled to the macro-chamber and the plurality of reagent sources and configured to receive one or more reagents among the plurality of reagents from at least one of the macro-chamber, the plurality of reagent sources, and react the one or more reagents to generate reaction content. The macro-chamber is further configured to receive the reaction content from the microfluidic reactor. A system configured to control at least one of flow of a dry gas in and out of the macro-chamber, surface area of at least one of the one or more reagents, and the reaction content in the macro-chamber. | 10-03-2013 |
20140333268 | SYSTEM AND METHOD FOR IMPROVING RESPONSE TIME OF A BRAKING UNIT - A braking system includes a converter, a capacitor coupled to an output of the converter, a bridge coupled in parallel to the capacitor, and at least one inductor coupled to the bridge, an electrically conductive disc disposed proximate to the at least one inductor, and a switching unit controller for commanding the converter to convert a level of voltage supplied therefrom from a first voltage level to a second voltage level and thereby increase energy stored in the capacitor, and, upon receiving a brake command, commanding the bridge to ramp-up electrical current in the at least one inductor so as to induce an electromagnetic force on the electrically conductive disc. | 11-13-2014 |
20150061298 | SYSTEMS AND METHODS FOR CONTROLLING ACCELERATION OF A POWER GENERATOR - An electromagnetic braking system includes an electrically conductive disc coupled to a rotatable shaft of a power generation system for operating in an island mode. The rotatable shaft is operatively coupled between a prime mover and a generator for supplying power to an island grid. The electromagnetic braking system further includes a controller for receiving at least one status or synchronization signal and for generating a control signal based on the at least one signal and an inducting unit for applying an electromagnetic braking force on the electrically conductive disc when commanded by the control signal to regulate a rotational speed of the rotatable shaft. | 03-05-2015 |