Bernhard Mueller
Bernhard Mueller, Dusslingen DE
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20110003971 | MODULATORS AND MODULATION OF THE INTERACTION BETWEEN RGM AND NEOGENIN - This invention relates to drug screening using mammalian repulsive guidance molecules and mammalian Neogenin. In addition, the invention provides for methods of preventing, alleviating or treating various disorders of the nervous system, angiogenic disorders or disorders of the cardio-vascular system and malignancies of different etiology by disrupting the interaction between RGM and Neogenin. | 01-06-2011 |
20130101605 | MODULATORS AND MODULATION OF THE INTERACTION BETWEEN RGM AND NEOGENIN - This invention relates to drug screening using mammalian repulsive guidance molecules and mammalian Neogenin. In addition, the invention provides for methods of preventing, alleviating or treating various disorders of the nervous system, angiogenic disorders or disorders of the cardio-vascular system and malignancies of different etiology by disrupting the interaction between RGM and Neogenin. | 04-25-2013 |
Bernhard Mueller, Neustadt DE
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20100322948 | Bone morphogenetic protein (BMP)-binding domains of proteins of the repulsive guidance molecule (RGM) protein family and functional fragments thereof, and use of same - The present invention relates to the identification and use of bone morphogenetic protein (BMP)-binding domains of members of the repulsive guidance molecule (RGM) protein family, and polypeptide fragments and fusion proteins derived therefrom. The domains, i.e., peptide fragments and fusion proteins, according to the invention are suitable as agents for the active or passive immunization of individuals, or as diagnostic and therapeutic agents for use for diseases or medical conditions in whose origin or progression a member of the RGM family and a cellular receptor associated with this molecule, such as neogenin and/or BMP in particular, is involved. The invention further relates to monoclonal and polyclonal antibodies directed against the binding domains according to the invention, and against the polypeptides derived therefrom, and to methods for producing the polypeptides, fusion proteins, and antibodies according to the invention. | 12-23-2010 |
Bernhard Mueller, Poing DE
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20100188666 | METHOD FOR BEAM CALIBRATION AND USAGE OF A CALIBRATION BODY - The invention relates to a method of calibration of the beam position of a corpuscular beam. A calibration body with structures is used, wherein the structures have a structure period P | 07-29-2010 |
Bernhard Mueller, Finsing DE
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20100097086 | APPARATUS AND METHOD FOR ACTIVE VOLTAGE COMPENSATION - A voltage compensation assembly adapted for apparatus having a prober for contacting the electronic elements on a substrate is described. The voltage compensation assembly includes a controller connected to the prober and adapted for active voltage compensation, and a voltage measuring unit connected to the controller and for measuring a voltage on the substrate. | 04-22-2010 |
Bernhard Mueller, Neustadt-Gimmeldingen DE
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20090304693 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 12-10-2009 |
20130330343 | COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF IRON-RELATED DISORDERS - Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders. | 12-12-2013 |
20130330347 | COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH NEURITE DEGENERATION - Provided herein are antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders. | 12-12-2013 |
20130330359 | COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF IRON-RELATED DISORDERS - Provided herein are antibodies and methods of using the antibodies to treat, prevent, modulate, attenuate and diagnose iron-related disorders. | 12-12-2013 |
20140023659 | COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH NEURITE DEGENERATION - Provided herein are antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders. | 01-23-2014 |
Bernhard Mueller, Budenheim DE
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20110226782 | GAS TEMPERATURE MODERATION WITHIN COMPRESSED GAS VESSEL THROUGH HEAT EXCHANGER - A pressure vessel for storing fuel cell reactants is disclosed. The pressure vessel includes an inner shell formed from a moldable material and forming a cavity therein, and an outer shell formed about the inner shell. A heat transfer member is disposed within the vessel cavity. The heat transfer member is thermally coupled a suitable external thermal mass external the pressure vessel to minimize the effect of thermal energy on the vessel. The heat transfer member may be a metallic structure within the cavity, or may be integrated within the inner shell on an inner shell surface. The external thermal mass may further be thermally coupled to either an active or a passive external thermal handling system for controlling the temperature of the fluid within the vessel. | 09-22-2011 |
Bernhard Mueller, Kempten DE
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20120013056 | CHARGING FRAME AND QUENCHING DEVICE HAVING A CHARGING FRAME - A charging frame for accommodating a batch of parts to be quenched, e.g., metal workpieces, has a circumferentially closed peripheral wall which surrounds the batch and thereby forms a flow channel which prevents bypass flows. The charging frame is a part of a quenching device. | 01-19-2012 |
20120067467 | QUENCHING DEVICE AND QUENCHING METHOD - A quenching device is described that includes at least one chamber that can be filled with quenching gas and that has a blower wheel for circulating quenching gas, in particular a quenching chamber and/or a flow channel, a drive motor, situated outside the chamber, for driving the blower being allocated to the blower wheel. The drive motor is coupled to the blower wheel so as to transmit torque via a coupling that operates in contactless fashion. Also described is a related quenching method. | 03-22-2012 |
20120118344 | HEAT EXCHANGER AND METHOD FOR CONVERTING THERMAL ENERGY OF A FLUID INTO ELECTRICAL POWER - A heat exchanger for converting thermal energy of a fluid, e.g., exhaust gas of an internal combustion engine, into electrical power, has a flow channel for conveying a hot fluid, and at least one thermoelectric module for generating electrical power is thermally connected to the flow channel. The flow channel is manufactured from a ceramic material. Thermal expansion effects of the flow channel is reduced by the ceramic material of the flow channel so that the design complexity for converting thermal energy into electrical power is reduced. | 05-17-2012 |
Bernhard Mueller, Hurth DE
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20120251462 | Agent For Smoker Dehabituation - The present invention relates to rosmarinic acid for use in a method for smoker dehabituation, wherein the rosmarinic acid is preferably in the form of a dried, aqueous extract of leaves of lemon balm (Melissa officinalis). In addition, the present invention relates to foods and food supplements for use in a method for smoker dehabituation, wherein these foods and food supplements contain rosmarinic acid, in particular rosmarinic acid in the form of a dried, aqueous extract of leaves of lemon balm (Melissa officinalis). | 10-04-2012 |
Bernhard Mueller, Lippstadt DE
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20130300296 | LED FLASH LIGHT AND METHOD FOR INDICATING NEAR-END-OF-LIFE STATUS OF SUCH AN LED FLASH LIGHT - The invention comprises a method for indicating that an LED flash light for an aircraft such as an anti-collision or beacon or strobe LED light has reached a near-end-of-life status, wherein the LED flash light under normal operational condition within a given time interval generates a predetermined number of normal flashes with the number being one or more than one, e.g. two. The method comprises the steps of determining the actual photometric condition of the LED flash light, and comparing the actual photometric condition to a given condition in a normal flashing mode. If the actual condition deviates from the given condition by more than a predetermined amount, the LED flash light is operated in order to generate within the given time interval one additional near-end-of-life-indicating flash. | 11-14-2013 |
Bernhard Mueller, Herrenberg DE
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20130214124 | LIGHT CURTAIN - The invention relates to a light curtain for detecting objects within a monitored region. The light curtain comprises an arrangement of transmitters that emit light rays, an arrangement of receivers for receiving the light rays, and an evaluation unit. Object detection signals are generated in the evaluation unit in dependence on the receiving signals present at the outputs of the receivers. The light curtain is divided into sub-regions containing a specified number of transmitters and receivers. The individual sub-regions can be adjusted individually through separate parameter settings. A separate evaluation is realized in the evaluation unit for the individual sub-regions. | 08-22-2013 |
20130221204 | SENSOR ARRANGEMENT - A sensor arrangement comprises an arrangement of light curtains, and a trigger generator which cyclically generates trigger signals. Each trigger signal is transmitted to the light curtains, wherein a measuring operation is started following a delay time in each light curtain as a result of the trigger signal that is received. | 08-29-2013 |
Bernhard Mueller, Baden AU
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20140210120 | FLAME-RETARDANT REGENERATED CELLULOSE FILAMENT FIBERS AND PROCESS FOR PRODUCTION THEREOF - In a process for producing regenerated cellulose fibers, in which particles of a flame-retardant solid are incorporated into the fiber, the particles are placed into a mold, the dimension of which in a major axis of the particle is greater than in the two orthogonal minor axes of the particle, and the major axes of the particles in the fiber are aligned in a preferential direction parallel to the spinning direction thereof | 07-31-2014 |