August, US
Avery August, State College, PA US
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20100129400 | ATTENUATED VIRUSES, VACCINES AND METHODS OF USE THEREOF - The invention encompasses compositions and methods relating to viral polymerases having one or more substitutions of different amino acids at conserved regions of the polymerase yields enzymes with varying rates and fidelity of replication. A universally applicable, polymerase-mechanism-based strategy for production of attenuated viruses and anti-viral vaccines is disclosed. Attenuated viruses serve as vaccines and were shown to provide protection against poliovirus challenge in vivo. | 05-27-2010 |
Henry August, Chatsworth, CA US
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20110061318 | FIRESHIELD DEVICE FOR HOME PROTECTION AGAINST THREATENING WILDFIRES - The FIRESHIELD approach presented herein is unique and designed as a barrier-like device capable of preventing wildfire embers from entering a structure's attic through its air vents while preserving the mold-resistant qualities as that of an open air vent. Modifications of air vents to a rooftop's attic are to be made with the retrofitting of an oversized FIRESHIELD panel that is externally mounted with a narrow ‘standoff’ gapped region. This panel acts as a barrier to wildfire driven embers and also forms an inner air channel pathway that accommodates air ventilation to the attic. This unique design is called a FIRESHIELD device and covers the typical air vent with an external attachment device consisting of a low cost, sheet-like panel (such as an aluminum sheet) with attachment to the rooftop air vent so as to provide a narrow ‘standoff’ air gap for maintaining ventilation. In this manner, inner-attic rooftop fire starts typically caused by air vent ingested embers that initiate from urban wildfires can largely be avoided and many lives and homes could be saved due to the application of this invention. | 03-17-2011 |
20120104794 | BASE DRAG REDUCTION FOR ROAD VEHICLES AND 'AIRDROP' CARGO AIRCRAFT - Methods providing naturally driven routing of air bleed derived from the external air pressure field typically developed about a moving vehicle were conceived. By design, internal ductways are to be used for providing an open flow path from relatively higher air pressure sources (such as that in the undercarriage region of a driven car) into lower base pressure regions (typically developed aft of blunt trailing body regions) as are generally found on road and ‘airdrop’ cargo delivery air vehicles having open rear doors. Low energy air bleed flow injected into the vehicle's separated afterbody region acts to replenish entrained base flow and its base drag reduction is thereby achieved. | 05-03-2012 |
James Kermit August, Arvada, CO US
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20100042231 | RELIABILITY TOOLS FOR COMPLEX SYSTEMS - Tools for the maintenance of complex plants or systems are provided. A master equipment list of components included in a complex plant are organized according to systems. Those components that are critical to the function of the associated system are identified. A template modeling aspects of each critical component is prepared. Information included in applied templates can be reused in association with common or similar components. Particular information included in applied templates may include information related to critical parts within the component, and information regarding maintenance requirements and procedures associated with the component or parts included in the component. | 02-18-2010 |
Jared P. August, Pullman, WA US
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20100260066 | NETWORK DISCOVERY AND DATA TRANSFER USING SNMP IN AN ELECTRIC POWER TRANSMISSION OR DISTRIBUTION SYSTEM - Disclosed herein are systems and methods for performing network discovery and file transfer utilizing Simple Network Management Protocol (SNMP). According to one embodiment, a manager queries an agent device to obtain an agent device's neighbor address table comprising IP addresses of neighboring devices. IP addresses comprised in the agent device's neighbor address table may be added to a network inventory. The manager device may then iteratively query each device in the network inventory until each of the plurality of agent devices have been queried. According to one embodiment, a device may divide a data file into a plurality of sequenced partitions. A plurality of packets may be created containing the sequenced partitions. A receiving device may reconstruct the data file using the sequenced partitions. | 10-14-2010 |
Joseph August, Los Angeles, CA US
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20160105598 | VIDEO CAMERA WITH PRIVACY - Systems and methods are described for a network video camera device. Specifically, various techniques and systems are provided for embodiments of a network video camera with a blocking mechanism for privacy and control of the blocking mechanism. Embodiments of the present invention include a network video capture device. The network video capture device comprises a lens connected to a housing; a blocking mechanism, wherein the a blocking mechanism is configured to selectively block the lens from capturing video images, and wherein the blocking mechanism includes a physical body; an indication device, wherein the indication device is configured to provide visible feedback that the lens is blocked; and a circuit board having a data processor, a wireless transceiver, and a memory configured to store a customizable setting associated with the blocking mechanism. | 04-14-2016 |
Joseph William August, Elmhurst, IL US
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20150075481 | OIL PROPERTY MANAGEMENT SYSTEM AND METHOD FOR INTERNAL COMBUSTION ENGINE FUEL ECONOMY AND MINIMUM WEAR RATES - A system and method for managing the characteristics of engine oil in a lubrication system for an internal combustion engine is disclosed. Generally speaking, the method includes the steps of determining a target viscosity for the engine oil based on engine speed and engine load, determining a working viscosity which may be directly measured or determined based on engine oil temperature and engine oil type, comparing the target viscosity to the working viscosity, deriving a target engine oil temperature, and directing engine oil to one of an oil cooler, an oil heater, or neither when and until the target engine oil temperature is achieved. The oil viscosity management system includes an engine lubrication system having a volume of engine oil, a cooler coupled to the lubrication system, a heating mechanism also coupled to the lubrication system, a valving system for directing flow of the oil and coupled to each of the lubrication system, the cooler and the heating mechanism, a signal generator for generating a signal based on operational parameters of the engine, and an estimator for controlling the valving system in response to the signal. | 03-19-2015 |
J. Thomas August, Baltimore, MD US
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20120294879 | CONSENSUS SEQUENCE FOR INFLUENZA A VIRUS - Pandemic A(H1N1) continues its global spread, and vaccine production is a serious problem. Protection by current vaccines is limited by the mutational differences that rapidly accumulate in the circulating strains, especially in the virus surface proteins. New vaccine strategies are focusing at conserved regions of the viral internal proteins to produce T cell epitope-based vaccines. T cell responses have been shown to reduce morbidity and promote recovery in mouse models of influenza challenge. We previously reported 54 highly conserved sequences of NP, M1 and the polymerases of all human H1N1, H3N2, H1N2, and H5N1, and avian subtypes over the past 30 years. Sixty-three T cell epitopes elicited responses in HLA transgenic mice (A2, A24, B7, DR2, DR3 and DR4). These epitopes were compared to the 2007-2009 human H1N1 sequences to identify conserved and variant residues. Seventeen T cell epitopes of PB1, PB2, and M1 were selected as vaccine targets by analysis of sequence conservation and variability, functional avidity, non-identity to human peptides, clustered localization, and promiscuity to multiple HLA alleles. The vaccines composed of these epitopes, being highly conserved and temporally stable, would be useful for any avian or human influenza A virus. | 11-22-2012 |
20130011427 | FLAVIVIRUS SPECIES-SPECIFIC PEPTIDE TAGS FOR VACCINE AND DIAGNOSTIC USE - Flaviviruses represent an increasing global public health issue, with no prophylactic and therapeutic formulations currently available for many of them. The combination of factors such as evolutionary change, global warming and wide range of animal hosts suggest the possible occurrence of | 01-10-2013 |
20130195904 | HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) HIGHLY CONSERVED AND LOW VARIANT SEQUENCES AS TARGETS FOR VACCINE AND DIAGNOSTIC APPLICATIONS - We identified regions of the HIV-1 proteome with high conservation, and low variant incidence. Such highly conserved sequences have direct relevance to the development of new-generation vaccines and diagnostic applications. The immune relevance of these sequences was assessed by their correlation to previously reported human T-cell epitopes and to recently identified human HIV-1 T-cell epitopes (identified using HLA transgenic mice). We identified (a) sequences specific to HIV-1 with no shared identity to other viruses and organisms, and (b) sequences that are specific to primate lentivirus group, with multiclade HIV-1 conservation. | 08-01-2013 |
Kevin August, Kensington, MD US
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20100306072 | INSTANT FINANCIAL CREDIT SYSTEM - Systems, apparatus, and computer program products are provided that allow for a credit partner, such as a retailer, to process a customer credit card application at multiple point-of-sale/point-of-contact channels, such as a manned or self-service cash register, a manned or unmanned kiosk, partner web site, a call center or the like and, if the customer is approved, allow for the customer to transact using the approved credit account at the credit partner location/site. The systems, methods and computer program provide for integration of the credit application system within multiple point-of-sale channels without requiring a large degree of customization and/or configuration at the credit partner level. In addition, embodiments support both active and passive instant credit decision processing. | 12-02-2010 |
Nathanie J. August, Portland, OR US
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20110148489 | Adaptive digital phase locked loop - In some embodiments, a digital PLL is disclosed with a dynamically controllable filter for changing the effective DPLL bandwidth in response to one or more real-time performance parameters such as phase error. | 06-23-2011 |
Nathaniel J. August, Portland, OR US
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20120280729 | ADAPTIVE DIGITAL PHASE LOCKED LOOP - In some embodiments, a digital PLL (DPLL) is disclosed with a dynamically controllable filter for changing the effective DPLL bandwidth in response to one or more real-time performance parameters such as phase error. | 11-08-2012 |
20140169063 | METHOD AND APPARATUS FOR READING VARIABLE RESISTANCE MEMORY ELEMENTS - In some embodiments, detecting resistance in a resistive memory cell may be done using a pulse edge. For example, a pulse may be applied through a resistive memory data cell and another through a reference delay circuit to determine which path has the larger delay in order to determine the resistive state of the data cell in question. | 06-19-2014 |
20150155036 | APPARATUS FOR TIME DOMAIN OFFSET CANCELLATION TO IMPROVE SENSING MARGIN OF RESISTIVE MEMORIES - Described are apparatuses for time domain offset cancellation. One example of the apparatus includes: a variable resistance memory cell; a reference resistive memory cell; a detector to generate an output indicating timing relationship between a pulse arriving from the variable resistance memory cell and a pulse arriving from the reference resistive memory cell; and a logic unit to receive the output from the detector and to generate a control signal to the adjust timing relationship as indicated by the detector. | 06-04-2015 |
Pamela Anne August, Kensington, MD US
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20100206323 | HEADBAND - The present invention provides a headband that is constructed of a combination of elements. The headband is constructed in layers where by a top layer can be of any material including decorative materials or wicking materials. The bottom layer of comprises a material which functions to cling to the hair of the wearer by friction created at the interface of the material and the hair and of the user. Situated between the top and bottom layer is at least one facing layer providing absorption and/or starchiness or reduced pliability of the band. | 08-19-2010 |
Paul August, Boxford, MA US
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20090178151 | NUCLEIC ACID ENCODING A NOVEL PROSTAGLANDIN RECEPTOR PROTEIN AND METHODS OF USE THEREOF - Described herein is a novel member of the prostanoid receptor family, a guinea pig prostaglandin D2 receptor. Described are the receptor, the nucleic acid that encodes it, and various uses for both. | 07-09-2009 |
20100035807 | COMPOSITION AND METHOD FOR TREATMENT OF TUMORS - The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria. | 02-11-2010 |
20100152427 | NUCLEIC ACID ENCODING A NOVEL DP RECEPTOR PROTEIN AND METHODS OF USE THEREOF - Described herein is a novel member of the prostanoid receptor family, a guinea pig prostaglandin D2 receptor. Described are the receptor, the nucleic acid that encodes it, and various uses for both. | 06-17-2010 |
20130059298 | Composition and Method for Treatment of Tumors - The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria. | 03-07-2013 |
20130252837 | METHOD FOR MEASURING RESISTANCE OR SENSITIVITY TO DOCETAXEL - The present invention relates to novel and useful methods that predict or monitor a patient's response to a molecule of the taxoid family by measuring the increase or decrease of specific genetic markers as compared to controls. The present invention also provides kits that predict of monitor patient's response to a molecule of the taxoid family by measuring nucleic acid or protein levels of particular genetic markers and comparing their levels to controls or reference markers. | 09-26-2013 |
Richard J. August, Concord, CA US
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20120204653 | COMPENSATION OF STRESS EFFECTS ON PRESSURE SENSOR COMPONENTS - Pressure sensors having components with reduced variations due to stresses caused by various layers and components that are included in the manufacturing process. In one example, a first stress in a first direction causes a variation in a component. A second stress in a second direction is applied, thereby reducing the variation in the component. The first and second stresses may be caused by a polysilicon layer, while the component may be a resistor in a Wheatstone bridge. | 08-16-2012 |
20130341740 | COMPENSATION OF STRESS EFFECTS ON PRESSURE SENSOR COMPONENTS - Pressure sensors having components with reduced variations due to stresses caused by various layers and components that are included in the manufacturing process. In one example, a first stress in a first direction causes a variation in a component. A second stress in a second direction is applied, thereby reducing the variation in the component. The first and second stresses may be caused by a polysilicon layer, while the component may be a resistor in a Wheatstone bridge. | 12-26-2013 |
20140260650 | SILICON PLATE IN PLASTIC PACKAGE - Circuits, methods, and apparatus that provide pressure sensor devices where pressure sensors may be reliably attached to surfaces in device packages, and where the coefficients of expansion of the pressure sensor and the surface are at least approximately equal. Examples may provide pressure sensor devices where pressure sensors may be reliably attached to surfaces in device packages by providing interposers formed to prevent adhesives used to attach the pressure sensors to surfaces from blocking or encroaching into pressure sensor openings or cavities. These same features may be used to accurately locate a pressure sensor relative to the interposer. Embodiments of the present invention may provide pressure sensor devices where the coefficients of expansion of the pressure sensor and the surface are at least approximately equal by proving interposers that are formed of the same or similar material as the pressure sensors, such as silicon. | 09-18-2014 |
Richard John August, Concord, CA US
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20080252175 | Dithering mechanism for eliminating zero-rate bias in a gyroscope - Dithering mechanism and method for eliminating the effects of zero-rate bias in a rate sensor or gyroscope. Both continuously moving and indexing embodiments are disclosed. The mechanism includes a first part mounted in a fixed position centered about a dither axis perpendicular to the input axis of the gyroscope, a second part disposed coaxially of the first part and affixed to the sensing element of the gyroscope, and a plurality of piezoelectrically driven quartz flexure beams extending radially between the first and second parts for dithering the second part about the dither axis. In some embodiments, the dithering mechanism is formed separately from and affixed to the sensing element of the gyroscope, and in others it is formed integrally with the sensing element. In the indexing embodiments, radial arms and fixed stops limit movement of the mechanism between two fixed positions, and drive signals and holding potentials are applied alternately to dither the mechanism between the two positions and to hold it alternately in those positions during successive data acquisition periods. | 10-16-2008 |
Ryan Paul August, Waukesha, WI US
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20100142680 | SYSTEM AND METHOD TO MAINTAIN TARGET MATERIAL IN DUCTILE STATE - An x-ray tube includes a frame, an anode for generating x-rays disposed within the frame, a cathode disposed within the frame, where the cathode is configured to selectively emit an electron beam toward the anode, and at least one heating element disposed within the frame and configured to heat a portion of the anode. | 06-10-2010 |
Steven H. August, Portland, OR US
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20090070200 | ONLINE QUALITATIVE RESEARCH SYSTEM - An online research system delivers allows a researcher to script queries to be delivered to research participants, delivers the queries, collects research participant feedback, and aggregates the feedback for review and analysis by the researcher. Tools are provided which allow queries to be rapidly and easily scripted, and the researcher may situate the queries along a timeline to schedule their automatic delivery. Researchers may assign “tags” to feedback, wherein researchers may select content from feedback and apply a label, and thereafter rapidly access this content by referencing its label. As a result, researchers are able to rapidly catalogue useful content for use in compiling their findings regarding research participant feedback. | 03-12-2009 |
Thomas August, Baltimore, MD US
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20110110970 | CHIMERIC VACCINES - The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient. | 05-12-2011 |
20130295128 | CHIMERIC VACCINES - The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient. | 11-07-2013 |
Tim August, Mccomb, OH US
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20080248088 | Decontaminant edible product, methods of production and uses thereof - The invention relates to an edible product containing a decontaminant. Particularly, the invention relates to an edible product, for instance, a food-like product, containing an effective amount of activated charcoal to mitigate, substantially reduce or cause the cessation of at least one adverse effect associated with the ingestion of a toxic substance. The invention also relates to methods for manufacturing such a decontaminant edible product and uses thereof. | 10-09-2008 |
William August, Cambridge, MA US
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20120311958 | INSULATION ART - A manufacture for insulating a wall, said manufacture includes: an insulation board, and visual artwork on a surface of said insulation board. | 12-13-2012 |
Zachary A. August, Clifton Park, NY US
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20130000838 | FLUID MEDIUM NON-CONTACT CONSOLIDATION - A pressure head for use in a fiber placement system for thermoplastic composite materials is disclosed. Plies of thermoplastic composite tape are placed onto a mandrel to form a shaped object. The pressure head includes a nozzle and at least one delivery tube for providing fluid medium mixture to the nozzle body, wherein the nozzle directs the fluid medium onto a surface of the shaped object thereby providing a pressure on the surface without direct physical contact of the nozzle with the plies of thermoplastic composite tape. | 01-03-2013 |
20130164498 | THERMOPLASTIC COMPOSITE PREPREG FOR AUTOMATED FIBER PLACEMENT - An improved thermoplastic composite prepreg tape is disclosed. The prepreg tape is optimized for high-speed, high quality in-situ consolidation during automated fiber placement. Embodiments of the prepreg tape have uniform dimensions (cross section, width, and thickness), uniform energy absorption, uniform surface roughness, and sufficient resin at the surface to affect a bond between layers. | 06-27-2013 |
20140017620 | SUPERIMPOSED ZONES PROCESS HEATING - Embodiments of the present invention include a heating method and apparatus in which a plurality of heated regions is superimposed in order to improve energy density control. | 01-16-2014 |
20160023433 | THERMOPLASTIC COMPOSITE PREPREG FOR AUTOMATED FIBER PLACEMENT - An improved thermoplastic composite prepreg tape is disclosed. The prepreg tape is optimized for high-speed, high quality in-situ consolidation during automated fiber placement. Embodiments of the prepreg tape have uniform dimensions (cross section, width, and thickness), uniform energy absorption, uniform surface roughness, and sufficient resin at the surface to affect a bond between layers. A scattering agent is used in a polymer surface layer to enable a combination of scattering and absorption in the polymer surface layer. | 01-28-2016 |