Ann M.
Ann M. Bullion, King Of Prussia, PA US
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20120142668 | CATHEPSIN C INHIBITORS - Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease. | 06-07-2012 |
Ann M. Chahroudi, Decatur, GA US
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20140255426 | WNT PATHWAY INHIBITORS FOR TREATING VIRAL INFECTIONS - In certain embodiments, the disclosure relates to methods of treating or preventing a viral infection comprising administering an effective amount of a Wnt pathway inhibitor optionally in combination with one or more anti-viral agents. In certain embodiments, the subject is diagnosed with a chronic viral infection such as human immunodeficiency virus (HIV). | 09-11-2014 |
Ann M. Depaauw, Pickerington, OH US
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20110126390 | FLEXIBLE DUCT HAVING DIFFERENT INSULATIVE VALUES - Methods of providing flexible duct are provided. The methods include the steps of providing an inner core, the inner core having a cylindrical shape and an outer surface, providing a layer of insulation having a constant uncompressed thickness, fiber diameter and density, wrapping the layer of insulation around the outer surface of the inner core thereby forming a layered assembly, selecting an outer jacket from a set of outer jackets of different diameters, the selected outer jacket configured to compress the layer of insulation to a desired thickness and inserting the layered assembly into the selected outer jacket thereby forming flexible duct. The thickness of the compressed layer of insulation provides a desired insulative value. The outer jackets included in the set of outer jackets are configured to compress the layer of insulation into a plurality of flexible duct having different insulative values from each other. | 06-02-2011 |
Ann M. Gillenwater, Pearland, TX US
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20100210951 | Optical System for Imaging of Tissue Lesions - The present disclosure, according to one embodiment, relates to an optical device for direct visualization, imaging, and spectroscopic measurements of tissue abnormalities at various anatomical sites. Such sites include, but are not limited to, the oral cavity, the cervix, and the skin. In one embodiment, the device comprises: a frame; at least one light-emitting diode light source mounted on the frame for illuminating a tissue, wherein the at least one light-emitting diode light source is chosen from a fluorescent light source, a polarized white light source, and an unpolarized white light source; at least one loupe mounted on the frame for visually observing the tissue; at least one filter disposed between the tissue and the loupe for filtering light reflected from the tissue; and an energy source operably connected to the at least one light-emitting diode light source. | 08-19-2010 |
Ann M. Graybiel, Lincoln, MA US
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20120310105 | MONITORING TASK ENGAGEMENT USING BETA OSCILLATIONS - The invention provides methods and apparatuses for monitoring task engagement by measuring beta frequency oscillations in the brain. Changes in power, frequency, and/or coherency of beta frequency oscillations correlate to an individual's engagement in or disengagement from a task. Accordingly, beta frequency oscillations can be used to determine if an individual prematurely disengages from a task, to diagnose if a person has a disorder affecting task engagement, and to evaluate the efficacy of a treatment for a disorder. | 12-06-2012 |
Ann M. Gronda, New Brighton, MN US
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20110004159 | SYSTEM AND METHOD FOR INTRAPARENCHYMAL DRUG INFUSION - A system for performing an intraparenchymal drug infusion including a pump device, a delivery tube, a sensor, and a processor. The tube is fluidly coupled to the pump device, establishing an infusate pathway from the pump to an infusate exit port of the delivery tube. The sensor is positioned to sense a parameter indicative of pressure in the infusate pathway. Finally, the processor is programmed to generate information indicative of infusate delivery effectiveness of a drug infusion procedure based upon information from the sensor. In some embodiments, the processor generates a net infusion pressure profile, such as a pressure-time curve, and prompts display of the pressure profile to a neurosurgeon for subsequent evaluation of infusate delivery effectiveness. | 01-06-2011 |
Ann M. Kensler, Sugar Grove, OH US
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20110250322 | Plastic Packaged Nutritional Liquids Comprising HMB - Disclosed are nutritional compositions comprising a plastic package and a nutritional liquid contained therein, wherein the nutritional liquid comprises beta-hydroxy-beta-methylbutyrate (HMB) and at least one of fat, protein, and carbohydrate. It has been found that HMB provides a buffering effect in the nutritional liquid to thus minimize an acidic pH shift that is more prevalent in plastic packages, and thus help maintain product stability over time. | 10-13-2011 |
20110256272 | Aseptically Packaged Nutritional Liquids Comprising HMB - Disclosed are nutritional compositions comprising a peroxide-treated aseptic package and a nutritional liquid contained therein, wherein the nutritional liquid comprises beta-hydroxy-beta-methylbutyrate (HMB) and at least one of fat, carbohydrate, and protein. The HMB provides a buffering effect in the nutritional liquid to thus minimize an acidic pH shift that is prevalent in aseptically sterilized packages, and thus helps maintain product stability over time. | 10-20-2011 |
20110256297 | Nutritional Emulsions Comprising Calcium HMB and Soluble Protein - Disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB wherein soluble protein comprises from about 50% to 100% by weight of the total protein. Also disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB wherein soluble protein comprises from about 50% to 100% by weight of the protein and the emulsion has a weight ratio of soluble protein to calcium HMB of from about 5:1 to about 12:1. The nutritional emulsions are surprisingly stable and generate minimal or no bitter flavors or after taste over time. | 10-20-2011 |
20110256301 | Nutritional Emulsions Comprising Calcium HMB - Disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB, wherein the nutritional emulsion has a weight ratio of a soluble calcium binding capacity to soluble calcium of from about 2.3 to about 12.0. Also disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB, wherein the nutritional emulsion comprises less than 900 mg/L of soluble calcium in a weight ratio of calcium HMB to soluble calcium of from 6:1 to 15:1. The nutritional emulsions are surprisingly stable and generate minimal or no bitter flavors or after taste over time. | 10-20-2011 |
20130337144 | NUTRITIONAL PRODUCTS COMPRISING CALCIUM HMB AND CONJUGATED LINOLEIC ACID - Disclosed are nutritional products comprising calcium beta-hydroxy-beta methylbutyrate, conjugated linoleic acid, and protein. The nutritional product forms include nutritional liquids and nutritional powders. The nutritional products not only provide benefits for individuals concerned with muscle health and functionality, but also exhibit physical stability, sensory and/or aesthetic benefits in each of the selected product forms. | 12-19-2013 |
20140037797 | NUTRITIONAL PRODUCTS COMPRISING BETA-HYDROXY-BETA-METHYLBUTYRATE - Disclosed are shelf stable nutritional products including beta-hydroxy-beta-methylbutyrate (HMB) and an oxidatively active species such as iron or copper. The HMB restricts the capacity of the oxidative species to catalyze the oxidation of nutrients such as fatty acids and vitamins thereby imparting both nutritional benefits and sensory benefits to the nutritional products. | 02-06-2014 |
Ann M. Killary, Houston, TX US
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20120058901 | ASSAY FOR THE DETECTION OF RECURRENCE IN BREAST CANCER USING THE NOVEL TUMOR SUPPRESSOR DEAR1 - Certain aspects of the present invention relate to new diagnostic and prognostic methods involving DEAR1, a gene is located on the short arm of human chromosome 1. Specifically, analysis of expression or structure of this gene for prognosis or recurrence risk assessment is disclosed. | 03-08-2012 |
Ann M. Leen, Bellaire, TX US
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20110136228 | METHODS OF CELL CULTURE FOR ADOPTIVE CELL THERAPY - An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm | 06-09-2011 |
20110182870 | GENERATION OF CTL LINES WITH SPECIFICITY AGAINST MULTIPLE TUMOR ANTIGENS OR MULTIPLE VIRUSES - The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane. | 07-28-2011 |
20130102075 | METHODS OF CELL CULTURE FOR ADOPTIVE CELL THERAPY - An improved method of culturing cells for cell therapy applications that includes growing desired cells in the presence of antigen-presenting cells and/or feeder cells and with medium volume to surface area ratio of up to 1 ml/cm | 04-25-2013 |
Ann M. Miller, Columbia, PA US
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20080307726 | Spline installation systems - A demountable surface covering system which includes an elongated spline member that secures construction material to the building framing. Attaching construction material to the building framing via the spline member eliminates damage to the panels, which in turn, permits immediate reuse of all components of the system after the system is uninstalled. | 12-18-2008 |
Ann M. Redepenning, Crown Point, IN US
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20140318196 | THEFT-DETERRENCE DEVICE FOR MACHINERY AND METHOD OF USE - Theft-deterrence devices and methods adapted to assist in theft deterrence/prevention of machinery, for example, a man lift, whose controls include a joystick. Such a device includes an enclosure having an interior cavity defined by and between oppositely-disposed first and second ends of the enclosure, and an opening in the second end that communicates with the cavity and sized to enable a joystick to pass therethrough into the cavity. The cavity accommodates at least a portion of the joystick sufficient to prevent operation thereof. The device further includes an arm having a first portion permanently attached to the enclosure, a third portion comprising a through-hole that enables a shackle of a locking device to pass therethrough, and a second portion that permanently joins the first and third portions. | 10-30-2014 |
Ann M. Schoeb-Wolters, Lebanon, NJ US
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20080214388 | Methods to prepare catalyst compositions comprising small silica support materials - Methods are provided to prepare a catalyst system that includes at least one titanium compound, at least one magnesium compound, at least one electron donor compound, at least one activator compound, and at least one silica support material, the at least one silica support material having a median particle size in the range of from 20 to 50 microns with no more than 10% of the particles having a size less than 10 microns and no more than 10% of the particles having a size greater than 50 microns and average pore diameter of at least ≧220 angstroms. | 09-04-2008 |
20110130271 | ZIEGLER-NATTA CATALYST COMPOSITIONS FOR PRODUCING POLYETHYLENES WITH A HIGH MOLECULAR WEIGHT TAIL AND METHODS OF MAKING THE SAME - Methods of preparing a polymerization catalyst component is provided, in which a magnesium component, a Lewis acid solubilizing component, a titanium compound, optionally a transition metal compound different than the titanium compound, and typically an inert filler are combined in a slurrying agent and spray-dried to produce a catalyst precursor in the form of a substantially spherical and porous solid particle. The methods and catalysts of this disclosure can provide ethylene homopolymer and copolymer resins having a high molecular weight tail and a broadened molecular weight distribution as compared to more traditional Ziegler-Natta catalysts. | 06-02-2011 |
20110130531 | Methods for Polymerization Using Spray Dried and Slurried Catalyst - Methods for gas phase olefin polymerization are provided. The method can include combining a spray dried catalyst system with a diluent to produce a catalyst slurry. The catalyst system can include a metallocene compound. Ethylene, a continuity additive, and the catalyst slurry can be introduced to a gas phase fluidized bed reactor. The reactor can be operated at conditions sufficient to produce a polyethylene. The spray dried catalyst system can have a catalyst productivity of at least 12,000 grams polyethylene per gram of the catalyst system. | 06-02-2011 |
20120130032 | POLYMERIZATION PROCESS USING A SUPPORTED CONSTRAINED GEOMETRY CATALYST - A polymerization process includes contacting the following in a gas-phase reactor system under polymerization conditions for making a polymer product: a metallocene-based catalyst system including a supported constrained geometry catalyst, at least one monomer, and an additive selected from a group consisting of an aluminum distearate, an ethoxylated amine, and a mixture thereof. The additive may be selected from a group consisting of an aluminum distearate, an ethoxylated amine, polyethylenimines, and other additives suitable for use in the production of polymers for food contact applications and end products, including a mixture of a polysulfone copolymer, a polymeric polyamine, and oil-soluble sulfonic acid, in a carrier fluid, and mixtures thereof. | 05-24-2012 |
Ann M. Simon, Chicago, IL US
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20150127119 | Impedance Parameter Power Control for Lower Limb Assistive Device - Systems and methods are described that relate to the control of a powered lower limb assistive device with one or more joints, where a controller of the assistive device is configured to receive one or more user-generated signals, determine control information using information in the one or more user-generated signals, select one or more joint impedance parameters of the assistive device for adjustment, and, for a mode and state of the assistive device, adjust the selected joint impedance parameters as a function of the control information. Additionally, systems and methods are described that relate to the control of such an assistive device, where a controller of the assistive device is configured to receive one or more user-generated signals containing information about the ankle angle of the assistive device, and adjust the stiffness of the ankle joint of the assistive device as a function of the ankle angle. | 05-07-2015 |
Ann M. Szulwach, Middle Village, NY US
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20090275548 | COMPOUNDS AND METHODS FOR ACTIVATED THERAPY - Provided herein are compounds for detection, diagnosis and treatment of target tissues or target compositions, including hyperproliferative tissues such as tumors, using sonodynamic and/or photodynamic methods. In particular, photosensitizer and/or sonosensitizer compounds that collect in hyperproliferative tissue are provided. | 11-05-2009 |
Ann M. Taccardi, Pittsford, NY US
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20110193990 | CAPTURE CONDITION SELECTION FROM BRIGHTNESS AND MOTION - A model based method for capturing an improved archival image, including capturing at least two preview images of a scene that are analyzed for scene brightness and motion velocity in the scene. The analyzed data is used to calculate a ratio of pixel signal rate/pixel velocity which is used to select a capture mode, an ISO and an exposure time for capturing the archival image. | 08-11-2011 |
Ann M. Turnley, Victoria AU
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20080254023 | Treating Gliosis, Glial Scarring, Inflammation or Inhibition of Axonal Growth in the Nervous System by Modulating Eph Receptor - The present invention relates to a method of treating disorders of the nervous system and more particularly disorders associated with a gliotic response and/or an inflammatory response within the central nervous system and to therapeutic agents useful for same. More particularly, the present invention involves a method of preventing or reducing the amount of Eph receptor-mediated gliosis and/or glial scarring and/or inflammation and/or Eph receptor-mediated inhibition of axonal growth which occurs during and/or after disease or injury to the nervous system. The present invention also facilitates the identification of therapeutic agents which modulate Eph receptor-mediated signaling. The method and therapeutic agents of the present invention are useful for treating a range of nervous system diseases, conditions and injuries including, inter alia, paralysis induced by physiological-, pathological- or trauma-induced injury to the brain or spinal cord. | 10-16-2008 |
20100152284 | PREVENTION AND REVERSAL OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY - Provided herein are methods for treating or preventing neuropathy, neuropathy-related conditions, wherein the neuropathy or neuropathy-related conditions are induced by, or otherwise associated with, treatment of the subject with at least one chemotherapeutic agent, the methods comprising administering an effective amount of an isoflavonoid compound of formula (I). Also provided are methods for the treatment of nerve damage. Also provided are uses of isoflavonoid compounds of formula (I) in the treatment of neuropathy, neuropathy-related conditions and nerve damage. | 06-17-2010 |
Ann M. Ureneck, Red Bank, NJ US
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20110177016 | Long Wear Cosmetic Composition - The present invention is directed to a cosmetic composition containing at least one styrene/acrylate copolymer and retaining gloss properties, comfort without irritation, and staying power for up to about 8 hours. | 07-21-2011 |
Ann M. Wollrath, Groton, MA US
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20150149503 | PARALLEL ACCESS TO DATA IN A DISTRIBUTED FILE SYSTEM - An approach to parallel access of data from a distributed filesystem provides parallel access to one or more named units (e.g., files) in the filesystem by creating multiple parallel data streams such that all the data of the desired units is partitioned over the multiple streams. In some examples, the multiple streams form multiple inputs to a parallel implementation of a computation system, such as a graph-based computation system, dataflow-based system, and/or a (e.g., relational) database system. | 05-28-2015 |