Patent application number | Description | Published |
20090253137 | METHODS OF SCREENING FOR RISK OF PROLIFERATIVE DISEASE AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASE - A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore. | 10-08-2009 |
20110294193 | VIRAL VECTORS AND METHODS FOR PRODUCING AND USING THE SAME - A recombinant hybrid virus, including: (a) a deleted adenovirus vector genome comprising the adenovirus 5′ and 3′ cis-elements for viral replication and encapsidation, and further comprising a deletion in an adenovirus genomic region selected from the group consisting of: (i) the polymerase region, wherein said deletion essentially prevents the expression of a functional polymerase protein from said deleted region and said hybrid virus does not otherwise express a functional polymerase protein, (ii) the preterminal protein region, wherein said deletion essentially prevents the expression of a functional preterminal protein from said deleted region, and said hybrid virus does not otherwise express a functional preterminal protein, and (iii) both the regions of (i) and (ii); and (b) a recombinant adeno-associated virus (AAV) vector genome flanked by the adenovirus vector genome sequences of (a), said recombinant AAV vector genome comprising (i) AAV 5′ and 3′ inverted terminal repeats, (ii) an AAV packaging sequence, and (iii) a heterologous nucleic acid sequence, wherein said heterologous nucleic acid sequence is flanked by the 5′ and 3′ AAV inverted terminal repeats of (i). Methods of making and using the recombinant hybrid virus are also disclosed. | 12-01-2011 |
Patent application number | Description | Published |
20090052404 | METHOD AND APPARATUS FOR A SPECTRALLY COMPLIANT CELLULAR COMMUNICATION SYSTEM - A system for wireless data transmission that uses a channel bandwidth, channel separation, and radio frequency power spectrum which is compatible with existing deployments of wireless voice services. The transmitted waveforms are thus compatible with existing cellular networks. However, the time domain digital coding, modulation, and power control schemes are optimized for data transmission. Existing cellular network sites can thus be used to provide a high speed service optimized for wireless data traffic without the need for new radio frequency planning, and without interfering with existing voice service deployments. | 02-26-2009 |
20090149190 | OPTIMAL LOAD-BASED WIRELESS SESSION CONTEXT TRANSFER - A subscriber access unit for transferring session context in wireless communication is disclosed. The access unit contains first context establishing circuitry for establishing a first wireless session context associated with a first wireless coverage area; locating circuitry for determining whether the subscriber access unit is located concurrently in the first wireless coverage area and a second wireless coverage area; loading factor receiving circuitry for receiving a first loading factor and a second loading factor indicative of a throughput load associated with the first and second coverage areas respectively; comparison circuitry for comparing the first loading factor with the second loading factor; and second context establishing circuitry for selectively establishing a second wireless session context continuous with the first wireless session context, the second context associated with the second wireless coverage area, based on output of the circuitry comparing the first and second loading factors. | 06-11-2009 |
20090268705 | DYNAMIC BANDWIDTH ALLOCATION TO TRANSMIT A WIRELESS PROTOCOL ACROSS A CODE DIVISION MULTIPLE ACCESS (CDMA) RADIO LINK - A technique for transmission of wireless signals across CDMA radio links. Bandwidth is allocated dynamically within a session to specific CDMA subscriber unit based upon data rate determinations. Specifically, a dynamic bandwidth allocation algorithm operates from limits calculated based upon available ports per subscriber, expected user bandwidth, and parallel user bandwidth versus throughput. Provisions for priority service, unbalanced forward and reverse spectrum utilization, voice prioritization, and band switching are also made. | 10-29-2009 |
20110200017 | GRADE OF SERVICE AND FAIRNESS POLICY FOR BANDWIDTH RESERVATION SYSTEM - A scheme and a method for assigning priority levels to users based upon a history of their request for access to the resources is disclosed. If a user has, over a historical period of time, made fewer demands than a stated amount, that user is given a higher priority than a user who has made greater use of the resources than their stated amount. Thus, users making the heaviest demand on the available resources are allocated fewer resources despite their demand, whereas users that make less demands for the resources are granted more of the resources they request. | 08-18-2011 |
20120191443 | MODEL BASED VERIFICATION USING INTELLIGENT CONNECTORS - Verifying operation of a device, where the device may have one or more inputs and one or more outputs, with at least one input and/or output associated with an intelligent connector. The intelligent connector is a data structure that contains the name of a variable transported by that connector, an address of the variable itself as a value in memory, and further information of the device producing the variable, at least in the form of address or pointer to the device data structure and the addresses of all other devices consuming that variable. | 07-26-2012 |
20120192013 | Verification of Signal Processing Using Intelligent Points - A technique for debugging of a signal processing program or model (or the debugging and reconciliation of two independent software instantiations). Timelines (Vectors) of signal values for verification are condensed to a small amount of information, easy to understand and manage. The information is stored in “Intelligent Points”, which can be graphically specified by the test engineering. The Intelligent Points can include one or more attributes that describe how to generate the appropriate signals. The information so stored can then be automatically expanded to complete timelines. | 07-26-2012 |
20120192158 | Model Based Verification Using Forward and Reverse Traversal of Variable Time Line - A technique for debugging of a program model (or the debugging and reconciliation of two independent software model instantiations) with the perception of immediate showing of values assumed by all variables at any selected time, by permitting a user to move a selected test point in a forward and reverse direction along a time line, without recalculating the model each time the test point is moved. This is achieved by running the program model once and then saving all the variable values in memory, the values associated with the explicit name of the pertaining variable. | 07-26-2012 |
20120307804 | DYNAMIC BANDWIDTH ALLOCATION TO TRANSMIT A WIRELESS PROTOCOL ACROSS A CODE DIVISION MULTIPLE ACCESS (CDMA) RADIO LINK - A technique for transmission of wireless signals across CDMA radio links. Bandwidth is allocated dynamically within a session to specific CDMA subscriber unit based upon data rate determinations. Specifically, a dynamic bandwidth allocation algorithm operates from limits calculated based upon available ports per subscriber, expected user bandwidth, and parallel user bandwidth versus throughput. Provisions for priority service, unbalanced forward and reverse spectrum utilization, voice prioritization, and band switching are also made. | 12-06-2012 |
20130182682 | DYNAMIC BANDWIDTH ALLOCATION FOR MULTIPLE ACCESS COMMUNICATIONS USING BUFFER URGENCY FACTOR - A code division multiple access (CDMA) user device configured to dynamically allocating at least at least one wireless communication channel to permit a more efficient allocation of wireless communication channels when providing high speed data service. The CDMA user device is configured to receive data traffic from at least one data buffer in a base station. The CDMA user device is dynamically allocated at least one wireless communication channel based on an urgency factor. The urgency factor indicates the urgency of traffic data to be transmitted from the at least one data buffer in the base station to the CDMA user device. | 07-18-2013 |
20140254563 | METHOD AND APPARATUS FOR A SPECTRALLY COMPLIANT CELLULAR COMMUNICATION SYSTEM - A system for wireless data transmission that uses a channel bandwidth, channel separation, and radio frequency power spectrum which is compatible with existing deployments of wireless voice services. The transmitted waveforms are thus compatible with existing cellular networks. However, the time domain digital coding, modulation, and power control schemes are optimized for data transmission. Existing cellular network sites can thus be used to provide a high speed service optimized for wireless data traffic without the need for new radio frequency planning, and without interfering with existing voice service deployments. | 09-11-2014 |