Patent application number | Description | Published |
20080237905 | Preparation of polyphosphazene microspheres - Methods of producing polyphosphazene microspheres comprising admixing aqueous solutions of a water-soluble polyphosphazene and an organic amine, or salt thereof, are disclosed. | 10-02-2008 |
20090016935 | Coating formulations including polyphosphazene polyelectrolytes and biologically active agents and asperities coated with such formulations - A formulation for coating asperities, such as microprojections or microneedles, which comprises at least one polyphosphazene polyelectrolyte and at least one biologically active agent. Such formulation provides for improved loading and improved homogeneity of the at least one biologically active agent on the microprojections or microneedles. | 01-15-2009 |
20090017210 | METHODS AND SYSTEMS FOR COATING A MICRONEEDLE WITH A DOSAGE OF A BIOLOGICALLY ACTIVE COMPOUND - Methodologies and systems are disclosed for coating one or more microneedles, particularly in a microneedle array, for administering a predetermined dosage of biologically active compound through the skin to a recipient. The microneedles of the array are each immersed into at least one reservoir of a fluid liquid formulation of the biologically active compound wherein the at least one reservoir receives a metered predetermined amount of the formulation that corresponds to the dosage to be coated on each microneedle. The microneedles are immersed into the at least one reservoir one or more times to consume the entire amount of formulation in the at least one reservoir such the consumed amount forms the coating comprising one or more layers comprising the predetermined dose on each microneedle. Various embodiments are disclosed for immersing the microneedles one needle at a time, one or more times into the reservoir, or in an array into corresponding reservoirs in one or more repetitive immersions. The reservoirs may be repetitively filled to the predetermined amount to produce the desired single dosage on a microneedle. | 01-15-2009 |
20090041810 | Immunostimulating polyphosphazene compounds for intradermal immunization - Disclosed are intradermally administered products and methods for producing an immune response in a human or in an animal comprising an antigen and a polyphosphazene polyelectrolyte adjuvant in an amount effective to elicit an immune response in the human or in the animal against said antigen. | 02-12-2009 |
20100298525 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents - A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding. | 11-25-2010 |
20100322891 | Immuniostimulating polyphosphazene compounds - Polyphosphazene polymers having immunomodulating activity, and the biomedical use of such polyphosphazene polymers, in conjunction with an antigen or an immunogen are disclosed. | 12-23-2010 |
20110009570 | Preparation of polyphosphazene microspheres - Methods of producing polyphosphazene microspheres comprising admixing aqueous solutions of a water-soluble polyphosphazene and an organic amine, or salt thereof, are disclosed. | 01-13-2011 |
20110020421 | Biodegradable polyphosphazenes containing pyrrolidone side groups - Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed. | 01-27-2011 |
20120172455 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents - A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding. | 07-05-2012 |
20120214951 | PREPARATION OF POLYPHOSPHAZENE MICROSPHERES - Methods of producing polyphosphazene microspheres comprising admixing aqueous solutions of a water-soluble polyphosphazene and an organic amine, or salt thereof, are disclosed. | 08-23-2012 |
20120225116 | BIODEGRADABLE POLYPHOSPHAZENES CONTAINING PYRROLIDONE SIDE GROUPS - Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed. | 09-06-2012 |
20130137835 | Preparation of Polyphosphazene Microspheres - Methods of producing polyphosphazene microspheres comprising admixing aqueous solutions of a water-soluble polyphosphazene and an organic amine, or salt thereof, are disclosed. | 05-30-2013 |
20130261194 | Functionalized Water-Soluble Polyphosphazenes and Uses Thereof as Modifiers of Biological Agents - A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding. | 10-03-2013 |