51st week of 2015 patent applcation highlights part 6 |
Patent application number | Title | Published |
20150359664 | DEVICE FOR NON-SURGICAL COLD TREATMENT OF DISORDERS - A device for non-surgical cold treatment of disorders, like warts comprises a container containing a refrigerant having an outlet and a valve communicating with the outlet. An applicator is mounted to the container, said applicator having an outer wall and forming a chamber at least when connected to the container, a heat exchanger within the chamber in fluid communication with the outlet of the container and receiving refrigerant when the valve of the container is opened. A closed contact member is in heat exchange contact with the heat exchanger and is exposed to an outer side of the applicator. The heat exchanger comprises a porous member made of a material having a high thermal conductivity and adapted to conduct fluid refrigerant from the outlet of the container to the chamber while the refrigerant extracts heat from the heat exchanger and the contact member. | 2015-12-17 |
20150359665 | THERMAL BREAST PAD DEVICE - A thermal breast pad device that comprises of two straps that connect to each other via hook and loop materials, each strap has a pear shaped thermal pad disclosed on one end of each strap, each thermal pad defines a pear shaped aperture within each thermal pad and is split at a central location of each pear shaped thermal pad. Each pear shaped thermal pad is segmented into pockets that are evenly distributed. The pockets may be filled with flax seeds. The device can be used by nursing mothers, menstruating women, or women suffering from breast cancer that need a hot or cold compress to be draped around their breasts. | 2015-12-17 |
20150359666 | Cyclic Aperture Flow Regulator System - A cyclic aperture flow regulator system is disclosed to control flow exiting from a body cavity during surgery in a way that post-occlusion surges are effectively suppressed. The system is composed by an adjustable fluid aperture installed in a fluid path connecting the aspiration port of a surgical probe with a vacuum source, the probe to be inserted in a body cavity. The cross-sectional area of the fluid aperture can be modified by the action of an actuator portion driven by a controller. The controller commands the actuators in the actuator portion to modify the cross-sectional area of the adjustable fluid aperture in cycles. Each cycle of aperture dimension fluctuation includes at least one segment where the fluid aperture cross-sectional area is substantially reduced. The segment of each cycle where the cross-sectional area of the fluid aperture is substantially reduced can optionally include a transient complete closure of the aperture. The cycles of fluid aperture fluctuation are programmed to occur at a rate fast enough to produce a substantially steady flow, with minimum flow ripple and pressure ripple. Flow rate across the cyclic aperture flow regulator system is a function of the vacuum level of the vacuum source and can be regulated by adjusting the level of the vacuum. Flow rate across the cyclic aperture flow regulator system is also a function of the RMS value of the cross-sectional area of the fluid aperture and can be regulated by adjusting the amplitude of the waveform of each cycle. | 2015-12-17 |
20150359667 | SYSTEM FOR EYE MEDICATION COMPLIANCE AND TRACKING - Disclosed herein are a dispenser that contains a vial of eyedrops and a corresponding base station, both of which are designed according to medication dosing alerts, poka-yoke principles, and audible instructions to reduce the chances of improper usage. An example base station includes a set of dispenser receptacles, each receptacle being configured to receive and contain a respective specifically shaped dispenser from a set of dispensers associated with the base station, wherein each of the set of dispensers is uniquely shaped. The example base station includes a communications interface configured to receive eyedrop usage data from at least one of the set of dispensers, a storage device configured to store the eyedrop usage data, and an external communications interface configured to transmit the eyedrop usage data to at least one external device. The dispensers can hold a vial of medicine, and can include control circuits, sensors, buttons, a notification module, and communications interfaces. | 2015-12-17 |
20150359668 | LIGHT DELIVERY DEVICE AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - Devices and systems for delivering light to a target are described. Methods of using such light delivery device and system are also described. A method of using a photosensitizing compound with the light delivery device is also described. | 2015-12-17 |
20150359669 | OCT TRANSPARENT SURGICAL INSTRUMENTS AND METHODS - An ophthalmic instrument includes a shaft comprising a lumen. The instrument also includes a first arm extending from the lumen, the first arm having a first distal portion having a first flat tip. The instrument also includes a second arm extending from the lumen, the second arm having a second distal portion having a second flat tip that is positioned such that the second flat tip contacts the first flat tip when the first arm is forced towards the second arm. The first arm and the second arm comprise at least in part, a first material that is substantially transparent to electromagnetic radiation having a wavelength within a range of about 700-1200 nanometers (nm) and is substantially opaque to electromagnetic radiation having a wavelength within a range of about 400-700 nm. | 2015-12-17 |
20150359670 | OPHTHALMIC SURGICAL DEVICE - The invention relates to a device ( | 2015-12-17 |
20150359671 | ATTENUATED RF POWER FOR AUTOMATED CAPSULORHEXIS - A capsulorhexis apparatus includes a capsulorhexis probe configured for insertion into an eye through an incision and a pulse generator configured to deliver at least one radio-frequency (RF) pulse to the capsulorhexis probe. The delivered RF pulse has a pre-determined attenuation profile such that the power level of the delivered RF pulse is substantially attenuated over the RF pulse's duration. In some embodiments, the pulse generator is configured to deliver a series of two or more RF pulses to the eye, such that the energy of each of the second and subsequent pulses of the series is substantially attenuated relative to the energy of the immediately preceding pulse. | 2015-12-17 |
20150359672 | Systems and Methods for Disruption of an Eye Lens - Systems and methods are provided for ablating a lens of an eye. An access incision is made through outer eye tissue to access the lens. A laser tool is inserted through the access incision. Electromagnetic energy is focused using the inserted laser tool to ablate a portion of the lens, where said ablation breaks the lens into a plurality of pieces for removal from the eye. | 2015-12-17 |
20150359673 | DISPLAY FOR OPHTHALMIC SURGICAL CONSOLE WITH USER-SELECTABLE SECTORS - An ophthalmic surgical system includes a display device and a user interface. The display device generates a display on an image of a patient's eye comprising a plurality of non-overlapping display sectors. Each display sector displays one of a plurality of user-selectable surgical parameters. A user interface receives a user selection of one or more of the user-selectable surgical parameters to be displayed. | 2015-12-17 |
20150359674 | TREATMENT APPARATUS FOR OPERATIVELY CORRECTING DEFECTIVE VISION OF AN EYE, METHOD FOR GENERATING CONTROL DATA THEREFOR, AND METHOD FOR OPERATIVELY CORRECTING DEFECTIVE VISION OF AN EYE - A treatment device for the surgical correction of hyperopia in the eye comprising a laser device controlled by a control device. The laser device separating corneal tissue by applying laser radiation. The control device controls the laser device for emitting the laser radiation into the cornea such that a lenticule-shaped volume is isolated. Removal thereof effects the desired correction. The control device predefines the volume such that a posterior surface and an anterior surface are connected via an edge surface that has a width in projection along the visual axis that is wider than the one which a straight line in the same projection, that is perpendicular at the edge of the posterior or the anterior surface would have relative to the associated surface and connects the anterior surface to the posterior surface or to the perceived extension thereof. | 2015-12-17 |
20150359675 | ADHESIVE MOUNTABLE STACK OF REMOVABLE LAYERS - An eye protector includes a lens configured to protect the wearer from projectiles, and an optically clear stack attached to the lens. The stack can have one or more removable layers. The eye protector also includes an optically clear dry mount adhesive layer attaching the stack to the lens. The dry mount adhesive may be self-wetting to attach the stack to the lens so that air between the stack and the lens can be removed after the stack is attached and/or adhered to the lens, for example, by applying pressure across the surface of the stack. The refractive indices of the lens, the dry mount adhesive, and each removable layer are matched to within about 0.2. | 2015-12-17 |
20150359676 | HEADGEAR FOR PROTECTIVE HEADWEAR - In one aspect, a headgear for engaging and supporting protective headwear on a wearer's head is provided. The headgear may include a first side member on a first side of the headgear, a second side member on a second side of the headgear, and a forehead strap pivotally coupled to and extending between the first and second side members. The forehead strap may be configured to engage a wearer's forehead with the headgear worn by a wearer. The headgear may also include a second strap coupled to and extending between the first and second side members. | 2015-12-17 |
20150359677 | HEADGEAR FOR PROTECTIVE HEADWEAR - In one aspect, a split forehead strap of headgear is provided. In one aspect, a headgear for engaging and supporting protective headwear on a wearer's head is provided. The headgear includes a first side member on a first side of the headgear, a second side member on a second side of the headgear, and a forehead strap coupled to and extending between the first and second side members. The forehead strap is configured to engage a wearer's forehead with the headgear worn by a wearer. The forehead strap includes an upper member and a lower member spaced-apart from the upper member along at least a portion of the lower member to provide a cavity between the upper and lower member. In one aspect, a protective headwear is provided and includes a forehead strap defining a longitudinally extending cavity that alters in thickness. | 2015-12-17 |
20150359678 | Detachable Welding Face Mask - A welder's protective helmet is provided with a detachable face mask with a handle which allows the welder to detach the same, as desired, and hold the face mask in front of his/her eyes during welding but to easily and quickly move the same to the side for direct viewing. The handle can be provided with a forwardly directed V-shaped trough for holding the extension of the welding torch so that welding proceeds while the user's eyes are protected since the user's hand is holding both the welding torch in the trough of the handle which is also holding the face mask. | 2015-12-17 |
20150359679 | REMOVABLE SHIELD FOR PROTECTIVE HEADWEAR - In one aspect, a protective headwear is provided and includes a headgear, an outer shell rotatably coupled to the headgear, and a first shield coupled to the outer shell and rotatable between a first position and a second position. The first shield is selectively removable from the outer shell without the use of tools. The protective headwear also includes a second shield coupled to the outer shell. The first shield covers the second shield to a greater extent in the first position than in the second position. In one aspect, a method of manufacturing a protective headwear is provided. | 2015-12-17 |
20150359680 | PROTECTIVE HEADWEAR WITH AIRFLOW - In one aspect, a protective headwear is provided and includes an outer shell, a first shell duct coupled to the outer shell and including a first exhaust port, and a second shell duct coupled to the outer shell and spaced apart from the first shell duct. The second shell duct includes a second exhaust port. The protective headwear also includes a manifold positioned externally of the outer shell and configured to divert airflow into at least a first potion of airflow and a second portion of airflow. The manifold includes a first diversion member coupled to and in fluid communication with the first shell duct to provide the first portion of airflow to the first shell duct, and a second diversion member coupled to and in fluid communication with the second shell duct to provide the second portion of airflow to the second shell duct. | 2015-12-17 |
20150359681 | NON-INVASIVE VISION ENHANCEMENT - A method and system are provided for enhancing vision. The method includes capturing a first image by a first camera. The method further includes capturing a second image by a second camera. The method also includes combining the first image and the second image to form a combined image. The method additionally includes projecting the combined image on at least one eye of a user by a wearable image projection device. The combined image represents a wide screen image having a field of view greater than any of the first image and the second image taken individually | 2015-12-17 |
20150359682 | BAREFOOT ORTHOTIC - A barefoot orthotic is a foot support that adheres to the underside of a user's foot and is placed so that it extends longitudinally between the metatarsal head region and the calcaneal plantar tuberosity, and laterally between the lateral midfoot and the medial arch. By using a silicone polymer or other similar material, a barefoot orthotic can self-adhere to the skin of a user's foot. A barefoot orthotic can have a midfoot strike zone surrounding the forward portion of the calcaneal plantar tuberosity, a navicular support, a medial arch support, a forefoot propulsion pad, a lateral forefoot support, a lateral midfoot support, a cuboid support flange, a lateral heel support, and a balance rail extending longitudinally from the midfoot strike zone to the forefoot propulsion pad. Together, these components work to support and align the foot and thereby alleviate symptoms of various foot and leg conditions. | 2015-12-17 |
20150359683 | Process and Apparatus for Supply of Particulate Material to a Particulate Printing Process - A process and apparatus for depositing particulate material in a predetermined pattern onto a moving surface is disclosed. A particulate material may be fed under gravity from a hopper to a discharge zone containing a feed opening. A gas may be supplied, by a gas supply assembly, under pressure to the bulk of particulate material within the hopper discharge zone. The particulate material may be transferred through the feed opening to the surface of a transfer device, which contains a pattern of particulate-receiving recesses. The transfer device may rotate to a deposition zone and transfer the particulate material to a carrier layer. | 2015-12-17 |
20150359684 | METHOD FOR ASSEMBLING A WITHDRAWAL CORD WITH AN INTRAVAGINAL MEMBER - The present invention relates to methods of assembling a withdrawal cord with an intravaginal member. In some embodiments, the withdrawal cord is affixed to an intravaginal member through the use of an anchor. | 2015-12-17 |
20150359685 | DISPOSABLE PULL-ON GARMENT - An absorbent article having a longitudinal centerline, a front region, a crotch region, and a back region. The absorbent article has a main portion, a side portion, and a waist portion. The waist portion has a belt portion that has a front belt portion having elastomeric material and a back belt portion having elastomeric material. The front belt portion has a first elastic section and a second elastic section, each section having force zones. The back belt portion has a third elastic section and a fourth elastic section, each section having force zones. The force zones in the portions alternate between a high force zone and a low force zone in at least one belt portion. | 2015-12-17 |
20150359686 | Absorbent article with a bacterial isolation pad and hygienic gripping tabs - An absorbent article for personal hygiene is disclosed with an absorbent core sealed between a liquid impermeable garment-side liner and a liquid permeable body-side cover together with an attached bacterial isolation pad, consisting of an absorbent layer sealed between an extension of the liquid impermeable garment-side liner and a liquid permeable topsheet which can be positioned to overlay the anal region of the body-side cover. A detachable bacterial isolation pad from the absorbent article and from the body-side cover is provided. Hygienic gripping tabs at the front-facing end of the absorbent article and at the rear-facing end of the bacterial isolation pad allow sanitary handling during removal of a soiled article. | 2015-12-17 |
20150359687 | ABSORBENT ARTICLE - The present invention addresses the problem of providing an absorbent article in which a bonding part for bonding a liquid-permeable layer to an absorbent core has been formed in a low-basis-weight region of the absorbent core and which has all of sufficient flexural rigidity of the bonding part, sufficient bonding strength of the bonding part, and sufficient liquid-absorbing properties. This problem is solved with an absorbent core which comprises a first region that has a given absorbent-material basis weight and second regions (regions | 2015-12-17 |
20150359688 | WATER ABSORBENT STORAGE LAYERS - The present invention relates to improved water-absorbing storage layers for use in hygiene articles, the water-absorbing storage layers being essentially free of cellulose fibers. | 2015-12-17 |
20150359689 | BODY FLUID TEST ARRANGEMENT FOR AN ABSORBENT ARTICLE - A body fluid test arrangement for an absorbent article includes a body fluid test device for receiving and examining voided body fluid. The body fluid test arrangement is configured to attach to a topsheet of the absorbent article. The body fluid test arrangement includes a fastening means for attachment to the topsheet of the absorbent article by a peelable connection between the body fluid test arrangement and the topsheet. The fastening means provides an attachment of the body fluid test arrangement having a peel strength from 0.05 to 1.65 (N×cm)/cm | 2015-12-17 |
20150359690 | 360 DEGREE CHANNEL HINGED CUSION ASSEMBLY FOR SUSPENSION AND ALLEVIATION OF SITTING DISCOMFORT AND INJURY - A cushion assembly has two cushions that are loosely joined by a connector that proceeds through respective diagonal channels in respective corners of the two cushions. The connector has a length that loosely connects the cushions and, by a combination of this length and the diagonal channels, the cushions can be selectively configured co-planar with each other in a V-shape, with any arbitrary angle therebetween, and in a stacked configuration wherein the cushions are atop each other. The connector and the diagonal channels also allow the cushions to be configured at any selected angle between the V-shape configuration and the stacked configuration. | 2015-12-17 |
20150359691 | MOVEMENT ASSISTANCE ROBOT - There is provided a movement assistance robot in which a single type of movement assistance robot can take care of multiple users having different physical abilities. A movement assistance robot | 2015-12-17 |
20150359692 | SIT-TO-STAND APPARATUS AND METHOD - An orthotic apparatus comprising: a scat; and a trunk support movable horizontally and vertically relative to said seat, said trunk support configured to confine motion of a user to a predetermined range when the user independently transitions between sitting on said seat and standing, and vice versa, so as to guide the user in the transition. | 2015-12-17 |
20150359693 | LONG TERM CARE BED - An adjustable bed includes a fixed frame, an articulating frame supported on the fixed frame, first and second leg assemblies, and first and second actuators. The leg assemblies are configured to raise and lower the fixed frame between a lowered position and a raised position. The actuators are disposed and fully maintained within an interior volume of the fixed frame. The first actuator is fixedly secured at a first end to the head end of the fixed frame and operably coupled to the first leg assembly at a second end. The second actuator is fixedly secured at a first end to the foot end of the fixed frame and operably coupled to the second leg assembly at a second end. The first and second actuators are configured to exert a pulling force to raise the fixed frame and to exert a pushing force to lower the fixed frame. | 2015-12-17 |
20150359694 | CARE ROBOT - A care robot that assists a standing-upright motion or a sitting motion of a care receiver without making the care receiver uncomfortable. In the care robot, a standing-upright trajectory, along which a movement control portion of a care receiver moves, is set so a center of gravity of the care receiver is in a range of the soles of both feet between a point in time early after the start of a standing-upright motion and an end time point of the standing-upright motion of the care receiver. A sitting trajectory is set so the center of gravity of the care receiver is out of the range of the soles of both feet from a point in time early after the start of a sitting motion of the care receiver, and moves toward a predetermined sitting position of the care receiver. | 2015-12-17 |
20150359695 | BODY TRANSPORT APPARATUS - A body transport apparatus including an inflatable air mattress with a plurality of air exit holes on the bottom to provide an air cushion when the mattress is inflated and a cover portion connected to the mattress adjacent a perimeter to define an enclosed volume. The cover portion may include a selectively closeable passageway. A flap may be defined in the cover portion that is movable between open and closed configurations. A plurality of hollows may be defined in the cover portion when inflated to define a body contact area that is less than a surface area of the top surface. | 2015-12-17 |
20150359697 | WRIST AND FOREARM EXOSKELETON - An exoskeleton device and method of using the same is provided that helps rehabilitate limbs such has the lower arm. Embodiments of the exoskeleton device have multiple degrees of freedom so that a limb such as the lower arm may flex or rotate in multiple directions to establish or re-establish neural connections in the brain. With the lower arm example, a person may grasp a handle in the exoskeleton and then flex the lower arm about a pronation/supination axis, a flexion/extension axis, and/or an abductor/adductor axis. The exoskeleton device has several modes of operation where actuators can aid the person's motion, resist the person's motion, or passively allow free motion of the person's limb. | 2015-12-17 |
20150359698 | Actuators and Methods of Use - Actuators and methods of use are provided. An actuator may comprise an inner member made from an elastic material and defining a compartment for receiving an actuating fluid, the inner member being moveable in a longitudinal direction from a relaxed state to an expanded state by introducing an actuating fluid into the inner member; and an outer member made from an inelastic material and being disposed around the elastic inner member to control expansion of the elastic inner member in a radial direction, the outer member being moveable from a folded relaxed configuration to an unfolded extended configuration as the inner member moves from the relaxed state to the expanded state, wherein the movement of the actuator between the relaxed state and the expanded state causes a movement of a structure to which the actuator is attached. | 2015-12-17 |
20150359699 | ELECTRIC WALKING ASSISTANT DEVICE - An electromotive walking assistance device includes a drive unit including a plurality of wheels and a motor for driving at least on portion of the plurality of wheels, a sensor unit sensing a distance from a user, a manipulation unit sensing a user's manipulation, and a controller controlling the motor based on a signal of the distance from the user and a signal of the user's manipulation. | 2015-12-17 |
20150359700 | COMPRESSIVE THERAPEUTIC DEVICE - A device for compressing an extremity of a user includes a wearable support member operable to be worn on the extremity of the user. The device also includes a plurality of chamber members that are arranged across and coupled to the support member. The chamber members each have a respective chamber therein. The chamber is at least partially defined by a base wall that is disposed adjacent the support member, a side wall that is attached to and that extends away from the base wall, and a top wall that is attached to the side wall and that is spaced away from the base wall. Furthermore, a foot pump member is operable to be disposed underneath a foot of the user. The foot pump member is operable to change a pressure inside the chambers as a result of being stepped upon by the user. | 2015-12-17 |
20150359701 | Massage Apparatus and Methods of Use - A two sided fabric or sleeve sewn together having a center divide configured to create a primary sleeve and an over pressure flap, a compressible ball configured to freely move therein the primary sleeve and the over pressure sleeve is folded over the primary sleeve, thus to enable a hand held massage device capable of deep tissue self-massage of specific body parts. | 2015-12-17 |
20150359702 | LOW INTENSITY VIBRATION DEVICE DELIVERING MECHANICAL SIGNALS TO BIOLOGICAL SYSTEMS - A vibration device | 2015-12-17 |
20150359704 | Rechargeable Personal Massager - A personal massage device is disclosed. The massage device includes a housing having an exterior surface defining first and second oppositely-disposed operative ends and an interior surface defining a cavity. Each of the operative ends includes a substantially smooth and continuous surface thereon. The massage device further includes a first motor disposed within the housing and adapted for creating vibration and a battery disposed within the housing and adapted to power the first motor. | 2015-12-17 |
20150359705 | DISPOSABLE COVER FOR AN EXTENDABLE ELEMENT OF AN AUTOMATED CPR DEVICE - Automated CPR unit comprising an extendable cover system including a cover dispenser ( | 2015-12-17 |
20150359706 | Method and Apparatus for Monitoring Manual Chest Compression Efficiency During CPR - A compression measurement and feedback system which measures the magnitude and the angle of manual CPR force applied to a patient and provides the measured magnitude and direction information as compression data feedback to the person applying CPR to the patient. Any variation in the magnitude or direction of the compression force applied may be calculated from the compression data measured by the compression sensor. A monitor receives the compression data and processes the compression data to generate feedback data to the CPR provider indicating the magnitude and direction of the applied CPR compression along with ideal CPR compression characteristics for comparison. | 2015-12-17 |
20150359707 | Access Assembly with a Pierceable Sealing Member - The present invention relates to an access assembly to provide access to the interior of a vessel and comprising: a base to extend through a sidewall of the vessel and having a tubular sealing portion providing a passageway axially extending therethrough, a pierceable sealing member arranged across the sealing portion to obstruct the passageway, at least one closure member axially displaceable relative to the base between a sealing position, in which the closure member completely obstructs and seals the passageway, and a leakage position, in which the closure member leakily obstructs the passageway. | 2015-12-17 |
20150359708 | AFFIXED GROUPS OF PHARMACEUTICAL VIALS INCLUDING FRANGIBLE CONNECTORS - In some embodiments, an affixed group of pharmaceutical vials with frangible connectors includes: a plurality of pharmaceutical vials arranged as a group of pharmaceutical vials, each of the plurality of pharmaceutical vials shaped and positioned to minimize a total volume of the group of pharmaceutical vials, each of the pharmaceutical vials including at least one external side with a surface configured to reversibly mate with a corresponding external side and a surface of an adjacent pharmaceutical vial; and a plurality of frangible connectors, wherein at least one frangible connector is affixed to the surface of at least two of the plurality of pharmaceutical vials within the group of pharmaceutical vials, and at least one frangible connector is affixed to each of the plurality of pharmaceutical vials. | 2015-12-17 |
20150359709 | CLOSED DRUG TRANSFER SYSTEM - The application describes innovative designs for components of a drug transfer apparatus that overcome problems encountered in daily use of prior art apparatuses. Specifically described are components configured to prevent liquid from entering the air chamber of syringes coupled to the apparatus and to prevent tearing of the rubber stopper of drug vials when they are attached to the apparatus. | 2015-12-17 |
20150359710 | MEDICINAL CEFOXITIN VIAL, AND DISPENSING APPARATUS AND INJECTION APPARATUS THEREOF - A medicinal xiding vial, and a dispensing apparatus and an injection apparatus thereof, comprise a reversely pressed medicinal xiding vial, a reversely pressed dispensing apparatus and a reversely pressed injection apparatus thereof, a general medicinal xiding vial, and a general injection apparatus. The reversely pressed medicinal xiding vial comprises a vial body whose inner wall is a straight cylinder. A first piston is disposed on a position close to the vial opening of the vial body. A blind hole is disposed at the center of an outer bottom surface of the first piston. The vial opening is provided with an outer edge, and a seal cap is fixed on the out edge to prevent the first piston from falling off. In combination with the dispensing apparatus and the injection apparatus thereof, the medicinal xiding vial can solve the problem of secondary pollution during medicine dispensing and injection. | 2015-12-17 |
20150359711 | PRESCRIPTION CONTROL SYSTEM - A medication dispensing device comprises a cartridge unit and a control unit. The cartridge unit comprises a cartridge housing defining a dispensing channel to allow passage of the dosage from the cartridge to the patient. A cartridge holds dosages, with a driven member engaging the cartridge. The driven member drives the cartridge to dispense a dosage. The control unit comprises a main housing for coupling to the cartridge housing. A driver member engages the driven member to actuate the driven member. A motor driven locking mechanism is moveable between locked and unlocked positions. When in the locked position the cartridge unit is secured to the control unit. When in the unlocked position the cartridge unit is separable from the control unit thereby providing access to the cartridge. A mobile computing device stores dosage availability and receives an authorized patient identification input before dispensing a dosage. | 2015-12-17 |
20150359712 | CARTRIDGES FOR THE DEPOSITION OF TREATMENT COMPOSITIONS ON KERATINOUS SURFACES - A micro electromechanical ink jet printing system that has a cartridge having a body that defines a core, and a die that contains one or more nozzles. There is a treatment composition contained within the cartridge core. The system further includes a CPU that is programmable and can control the application of the treatment composition from within the cartridge core, through the one or more nozzles to human skin. Typically, the treatment composition will contain a skin treatment ingredient selected from the group consisting of particles, vitamins, yeast and yeast extracts, skin care actives, dyes, colorants and mixtures thereof. There may optionally be provided a bladder or foam block disposed within the cartridge core for suspending and regulating the flow of the treatment composition. The systems of this invention may include an applicator having an applicator head having one or more applicator nozzles which may be in a array. The applicator has a sensor that takes an image of at least 10 μm | 2015-12-17 |
20150359713 | COMPOSITIONS AND METHODS FOR ENHANCING THE TOPICAL APPLICATION OF A COLOR COSMETIC - A powder is disclosed including a first powder of core/shell particles having an average particle size of less than 1000 microns, each particle contains a liquid core that is substantially free of water that includes a polar liquid having a percent surface polarity of at least 24%; and a shell comprising hydrophobic particles and a second powder including a color cosmetic. | 2015-12-17 |
20150359714 | TREATMENT COMPOSITIONS, APPARATUS AND METHODS FOR MODIFYING KERATINOUS SURFACES - A treatment composition for treating human skin that has one or more particulate suspending agents in a concentration of from about 0.05% to about 2.0%, by weight, and one or more film forming polymers in a concentration of from about 0.1% to about 5.0%, by weight. Further, particles in a concentration of from about 1.0% to about 20.0%, by weight; one or more humectants in a concentration of from about 2.0% to about 20.0%, by weight; and, water are provided. The treatment compositions of this invention are used in an applicator having an applicator head having one or more applicator nozzles which may be in a array. The apparatus further has a reservoir containing the treatment composition, a sensor, and a CPU. The sensor takes an image of at least 10 μm | 2015-12-17 |
20150359715 | TRANS-RESVERATROL OR TRANS-RESVERATROL DERIVATIVE COMPOSITION - The invention relates to a cosmetic or dermatological composition which includes, in a physiologically acceptable medium, at least trans-resveratrol and/or at least one trans-resveratrol derivative, and an organic filtering system including at least one UVA filter and at least one UVB filter and/or at least one mixed UVA-UVB filter, said composition having an SPF no lower than 15 and a PPD no lower than 5. The invention also relates to a use of a filtering system which includes at least one UVA filter and at least one UVB filter and/or at least one mixed UVA-UVB filter for stabilising, in particular photostabilising, a composition including trans-resveratrol and/or at least one trans-resveratrol derivative. | 2015-12-17 |
20150359716 | COMPOSITION FOR HAIR FRIZZ REDUCTION - A composition directed to an aqueous hair leave-on composition for hair frizz reduction comprising from about 0.15% to about 12.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following class: | 2015-12-17 |
20150359717 | HAIR CARE COMPOSITION - A kit for coloring hair comprising: i) a first composition comprising an anionic surfactant, 2-amino-6-chloro-4-nitrophenol and a polyphenol; (ii) a second composition comprising a transition metal salt and/or complex. | 2015-12-17 |
20150359718 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE SPECIFIC AMIDE COMPOUND - The present invention relates to a cosmetic or dermatological composition comprising, in a physiologically acceptable support: a) at least one merocyanine of formula (1) or (2). b) at least one oily phase comprising at least one amide compound of formula (I). The present invention also relates to a non-therapeutic cosmetic process for caring for and/or making up a keratin material, comprising the application, to the surface of the said keratin material, of at least one composition as defined above. The invention also relates to a non-therapeutic cosmetic process for limiting the darkening of the skin and/or improving the colour and/or uniformity of the complexion, comprising the application, to the surface of the keratin material, of at least one composition as defined previously. The invention also relates to a non-therapeutic cosmetic process for preventing and/or treating the signs of ageing of a keratin material, comprising the application, to the surface of the keratin material, of at least one composition as defined previously. | 2015-12-17 |
20150359719 | INTERNAL OLEFIN SULFONATE COMPOSITION - Provided are an internal olefin sulfonate composition which is capable of sufficiently enhancing foamability, foam spreadability, and foam dissipation property, and a cleansing composition containing the same. The internal olefin sulfonate composition comprises (A) an internal olefin sulfonate having 16 carbon atoms and (B) an internal olefin sulfonate having 14 carbon atoms, wherein a content mass ratio of the component (A) to the component (B), (A/B), is from 10/90 to 70/30, and a content of the internal olefin sulfonate having 18 or more carbon atoms is 5% by mass or less. | 2015-12-17 |
20150359720 | COSMETIC COMPOSITIONS - The present invention relates to a composition for topical application comprising at least a benzotriazol derivative, at least one dibenzoylmethane derivative and a cosmetic solvent selected from the group consisting of fatty acid triglycerides and/or sebacic acid esters or diesters. Furthermore, the invention relates to the use of at least one specific benzotriazol derivative for in creasing the water resistance of a dibenzoylmethane derivatives in a topical composition comprising a cosmetic solvent selected from the group consisting of fatty acid triglycerides and/or sebacic acid esters or diesters. | 2015-12-17 |
20150359721 | INCREASING MUSCULAR VOLUME IN A HUMAN USING HYALURONIC ACID - A method for increasing muscular volume of a muscle in a human is provided. The method comprises injecting a composition comprising hyaluronic acid (HA) into one or more than one location of a muscle, thereby increasing the muscular volume as compared to before the injection. The muscle may be an arm, leg, chest, back or buttock muscle, or any other desired muscle. A method for altering a contour of a muscle in a human is also provided, which comprises obtaining an image of the contour of the muscle, determining a new contour, injecting an HA composition into one or more than one location of the muscle to obtain the new contour, thereby altering the contour as compared to before the injection. A use of a composition comprising HA for increasing muscular volume of a muscle in a human is also provided, where the composition is for injection into muscle. | 2015-12-17 |
20150359722 | FLEXIBLE SOLID COSMETIC COMPOSITION COMPRISING ANIONIC SURFACTANTS AND SOLID PARTICLES, AND COSMETIC TREATMENT PROCESS - The present invention relates to an aqueous cosmetic composition which is in the form of a flexible solid, comprising:
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20150359723 | COMPOSITION EXTERNALLY USED FOR SUBACID SKIN AND COSMETIC MATERIAL INCLUDING SAME - The present invention relates to a weakly acidic composition for skin external application, which comprises a pH adjuster, a polymeric thickener and a multi-lamellar emulsion and has a pH of 3-5, preferably 3-4.5, and to a cosmetic formulation comprising the composition. The multi-lamellar emulsion in the weakly acidic composition of the present invention contains large amounts of dermatologically useful oleophilic substances, has skin barrier function, and is stably maintained at a relatively low pH, and thus the composition normalizes the pH of the skin to enhance or restore the skin's barrier function to thereby restore and maintain the skin in a healthy state, and effectively moisturizes the skin. In addition, the composition is maintained at suitable viscosity so as to be effectively prevented from phase separation. Also, the composition does not penetrate the skin, and thus causes no skin irritation. | 2015-12-17 |
20150359724 | Acrylate Gel Nail Coating Compositions - A polymerizable nail coating composition includes a reactive (meth) acrylate monomer; a reactive (meth) acrylate terminated polymer selected from the group consisting of a reactive (meth) acrylate terminated polyol polymer, a reactive (meth) acrylate terminated polyester polymer, a reactive (meth) acrylate terminated polyol urethane polymer, a reactive (meth) acrylate terminated polyester polymer, and combinations thereof wherein said polymer is derived at least in part from a polyether or a polyester having either a melting point between 20° C. and 60° C. or a glass transition temperature between 20° C. and 60° C.; and a polymerization photoinitiator, wherein upon exposure to radiant energy, said polymerizable nail coating composition cures to a photocrosslinked polymer. | 2015-12-17 |
20150359725 | Method of Treating Hair with a Concentrated Conditioner - A method of treating the hair including providing a concentrated hair care composition in an aerosol foam dispenser. The concentrated hair care composition includes one or more silicones, perfume, and less than 10% high melting point fatty compounds. The method also includes dispensing the concentrated hair care composition from the aerosol foam dispenser as a dosage of foam; applying the foam to the hair; and rinsing the foam from the hair. The foam has a density of from about 0.025 g/cm | 2015-12-17 |
20150359726 | Method of Treating Hair with a Concentrated Conditioner - A method of treating the hair including providing a concentrated hair care composition in a mechanical foam dispenser. The concentrated hair care composition includes one or more silicones, from about 1% to about 5% perfume, and is substantially free of high melting point fatty compounds. The method also includes dispensing the concentrated hair care composition from the mechanical foam dispenser as a dosage of foam; applying the foam to the hair; and rinsing the foam from the hair. The foam has a density of from about 0.025 g/cm | 2015-12-17 |
20150359727 | Method of Treating Hair with a Concentrated Conditioner - A method of treating the hair including providing a concentrated hair care composition in a dispenser. The concentrated hair care composition includes one or more silicones, perfume, and from about 2% to about 10% high melting point fatty compounds. The method also includes dispensing the concentrated hair care composition from the dispenser, applying the concentrated hair care composition the hair; and rinsing the concentrated hair care composition from the hair. | 2015-12-17 |
20150359728 | Method of Treating Hair with a Concentrated Conditioner - A method of treating the hair including providing a pre-aerated concentrated hair care composition. The pre-aerated concentrated hair care composition includes one or more silicones, perfume, and from about 2% to about 10% high melting point fatty compounds. The method also includes applying the pre-aerated concentrated hair care composition the hair; and rinsing the pre-aerated concentrated hair care composition from the hair. The pre-aerated concentrated hair care composition has a density of from about 0.15 g/cm | 2015-12-17 |
20150359729 | Lip Treatment Composition - A lip treatment composition for creating a perceptible tingling sensation when applied to mucosa membrane of a user. The composition has one or more base ingredients and at least one active ingredient, such as Zanthoxylum essential oil, that induces a perceptible tingling sensation reminiscent of electrical buzzing when applied to the mucosa membrane of the user. The Zanthoxylum essential oil could comprises between approximately 2.0000% and 4.0000% by weight of the composition and could comprise approximately 3.3000% by weight of the composition. The lip treatment composition can be formed under a process including heating the one or more base ingredients, adding the at least one active ingredient, and mixing the one or more base ingredients and the at least one active ingredient. | 2015-12-17 |
20150359730 | BASELLA ALBA EXTRACTS AND METHODS OF USE - Methods of using extracts of | 2015-12-17 |
20150359731 | PHYLLANTHUS ACIDUS EXTRACTS AND METHODS OF USE - Methods of using extracts of | 2015-12-17 |
20150359732 | VERNONIA CINEREA EXTRACTS AND METHODS OF USE - The present invention is directed to methods of using extracts of | 2015-12-17 |
20150359733 | DENDROBIUM CHYSOTOXUM EXTRACT AND ITS COSMETIC USE AS AN ANTI-AGING AGENT - The invention relates to a cosmetic composition comprising at least one extract from the orchid | 2015-12-17 |
20150359734 | FORMULATIONS FOR LIGHTENING SKIN AND TREATING HYPERPIGMENTATION - Formulations to treat skin discoloration via a multi-modal approach are provided in which select ingredients work together to effectively brighten skin and treat hyperpigmentation. An example formulation includes a first anti-melanin agent, a second anti-melanin agent, an anti-inflammatory agent, a sun protection agent, and an anti-oxidant. In one aspect, the first anti-melanin agent comprises a | 2015-12-17 |
20150359735 | ORAL AND/OR BUCCAL COMPOSITION IN THE FORM OF A THIN FILM OF A WEAKLY SOLUBLE ACTIVE INGREDIENT, METHOD OF PREPARING SAME AND USE OF SAME - The present invention relates to an oral and/or buccal composition in the form of a thin film of a pharmaceutically active ingredient weakly soluble in water and gastro-intestinal tract fluids, comprising particles of said active ingredient dispersed in a film-forming polymer, at least 50% by weight of the total weight of the active ingredient having a particle size distribution such that at least 90% of said particles have a size below 1000 nm, preferably less than 800 nm, and even more preferably less than 600 nm, and to the method of preparing that composition and the use thereof. | 2015-12-17 |
20150359736 | COMPOSITIONS COMPRISING RANK/RANKL ANTAGONISTS AND RELATED COMPOUNDS FOR TREATING PAIN - Disclosed herein are methods of treating pain using comprising RANK/RANKL antagonists. | 2015-12-17 |
20150359737 | SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION - According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy. | 2015-12-17 |
20150359738 | Methods of Anesthetizing Nerve Tissue in the Trigeminal Nerve Pathway and Medical Uses Thereof - Provided herein are methods of locally and specifically anesthetizing nerve tissue in the trigeminal nerve pathway and methods of performing a surgical procedure on a subject in need thereof that include intranasally administering (1) a pharmaceutical composition that includes a local anesthetic agent and a mucosal absorption enhancer to a subject in need thereof, where the local anesthetic agent and mucosal absorption enhancer are present in an amount sufficient to anesthetize nerve tissue in the trigeminal nerve pathway upon administration, or (2) a pharmaceutical composition that include a free-base form of a local anesthetic agent, where the free-base form of the local anesthetic agent is present in an amount sufficient to anesthetize nerve tissue in the trigeminal nerve pathway upon administration. | 2015-12-17 |
20150359739 | EDIBLE FILM-STRIPS FOR IMMEDIATE RELEASE OF ACTIVE INGREDIENTS - The present invention is directed to an edible film that contains two or more segmented portions and comprises an active ingredient that is distributed on a segmented portion or portions which comprise less than 50% of the cross sectional surface area of a major face of said film. The present invention also relates to methods of treatment for the treatment of various conditions and for taste-masking of pharmaceutical ingredients. | 2015-12-17 |
20150359740 | COMPOSITION AND METHOD FOR COMPOUNDED THERAPY - A compounded transdermal cream may include gabapentin, diclofenac, cyclobenzaprine, or a combination thereof. The compounded transdermal cream may further include lidocaine in an amount between approximately 0.5% to approximately 5.0% by weight of the compounded transdermal cream and prilocaine in an amount between approximately 0.5% to approximately 5.0% by weight of the compounded transdermal cream. | 2015-12-17 |
20150359741 | Formation of Particle Structures - Irregular, angular particles are produced by a manufacturing method that comprises forming a film on a substrate and then stretching the substrate along one or more axes to fracture the film into particle structures. The substrate may be moved continuously along a production line as the film is formed and may be stretched by accelerating that movement. The substrate may comprise a surface with elevated patterns to control the fracturing of the film. The particles are particularly suitable for the transdermal delivery of a biologically active substance into the body of a patient. | 2015-12-17 |
20150359742 | COMPOSITIONS AND METHODS FOR ENHANCING THE TOPICAL APPLICATION OF A BENEFIT AGENT INCLUDING POWDER TO LIQUID PARTICLES AND A SECOND POWDER - A powder is disclosed including core/shell particles having an average particle size of less than 1000 microns, each particle contains a liquid core that is substantially free of water and includes a polar liquid having a percent surface polarity of at least 24% and a shell comprising hydrophobic particles; and at least one second powder comprising a benefit agent. The powder can be used to topically administer the active ingredient to a human or animal. | 2015-12-17 |
20150359743 | SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION - The present disclosure provides compositions having different dissolution profiles. In particular, the compositions are formulated by adjusting the types and/or amounts of excipients and/or surfactants, and the compositions are prepared by spray drying processes. | 2015-12-17 |
20150359744 | METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF ACTIVE AGENTS FOR CRYSTALLINE MICROPARTICLE SURFACES - Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle. | 2015-12-17 |
20150359745 | Sodium bicarbonate particles manufactured by atomization - Method for producing sodium bicarbonate particles by spray-drying of an aqueous solution comprising 1 to 10% by weight of sodium bicarbonate and an additive selected from the group consisting of: magnesium salt, sodium alkylbenzene sulfonate and soybean lecithin. Sodium bicarbonate particles obtainable by such process and comprising at least 20 mg of the additive per kg of sodium bicarbonate particles. | 2015-12-17 |
20150359746 | Technology for the Preparation of Microparticles - Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. | 2015-12-17 |
20150359747 | ABUSE-PROOFED DOSAGE FORM - The invention relates to a dosage form that is thermoshaped without being extruded and that is safeguarded from abuse, comprising at least one synthetic or natural polymer having a breaking strength of at least 500 N in addition to one or more active substances that could be subject to abuse and optionally physiologically acceptable adjuvants. The invention also relates to a corresponding method for producing said dosage form. | 2015-12-17 |
20150359748 | MODIFIED RELEASE PREPARATIONS CONTAINING OXCARBAZEPINE AND DERIVATIVES THEREOF - Controlled-release preparations of oxcarbazepine and derivatives thereof for once-a-day administration are disclosed. The inventive compositions comprise solubility- and/or release enhancing agents to provide tailored drug release profiles, preferably sigmoidal release profiles. Methods of treatment comprising the inventive compositions are also disclosed. | 2015-12-17 |
20150359749 | FORMULATIONS OF GUANYLATE CYCLASE C AGONISTS AND METHODS OF USE - The invention provides novel formulations of guanylate cyclase-C(“GCC”) agonist peptides and methods for their use in the treatment of gastrointestinal diseases and disorders, including gastrointestinal cancer. The GCC agonist formulations of the invention can be administered either alone or in combination with one or more additional therapeutic agents, preferably an inhibitor of cGMP-dependent phosphodiesterase or a laxative. | 2015-12-17 |
20150359750 | POSITIONING IMMEDIATE-RELEASE BIOADHESIVE AND APPLICATION THEREOF - Provided is a positioning immediate-release bioadhesive and relates to a medical device for preventing or/and treating diabetes, obesity, alcoholism, gastric and intestinal mucosal inflammation or/and ulcers and the like. The positioning immediate-release bioadhesive is prepared by preparing a biocompatible bioadhesive material into micro-particles, externally adding an immediate-release disintegrant, tabletting and then performing enteric or gastric coating; or performing enteric or gastric coating on the micro-particles; or filling into enteric-coated or gastric-coated hollow capsules; or directly tabletting the bioadhesive material, the immediate-release disintegrant and other additional agents and then performing enteric or gastric coating. After the positioning immediate-release bioadhesive is taken, the positioning immediate-release bioadhesive can realize positioning and immediate release, rapidly adhere to and cover the upper segment of duodenum and jejunum or/and gastric mucosa and weaken the absorption of the upper segment of duodenum and jejunum or/and stomach. The positioning immediate-release bioadhesive is orally administered, convenient to carry, convenient to store and convenient to use, and a patient using the positioning immediate-release bioadhesive does not need to go to a hospital, perform an operation or use endoscopy and further has no pain, thereby enhancing the compliance of a user and avoiding the complexity of the operation. | 2015-12-17 |
20150359751 | GAS-GENERATING NANOPARTICLE - Disclosed are gas-generating nanoparticles comprising fine-grained calcium carbonate crystals and a biocompatible polymer, the fine-grained calcium carbonate crystals being encapsulated inside the biocompatible polymer, and the diagnosis and treatment of diseases can be effectively performed at the same time by using a composition of the present disclosure. | 2015-12-17 |
20150359752 | ENZYME RESPONSIVE NANOCAPSULES FOR PROTEIN DELIVERY - The invention provides methods of making and using compositions comprising a polymer shell designed to deliver polypeptides to selected environments. In embodiments of the invention, different environmental conditions are harnessed to allow the selective degradation of the polymer shell and the consequential release of one or polypeptides encapsulated therein. In illustrative embodiments, polymer components of the shell are interconnected by peptide-containing crosslinker moieties, linkages which maintain the integrity of the polymer shell under certain environmental conditions, but can also be cleaved when combined with a selected protease. | 2015-12-17 |
20150359753 | LIQUID MENTHOL COMPOSITIONS - A composition is provided comprising: (i) menthol, and (ii) a carrier comprising a digestible edible oil, wherein said digestible edible oil is one that provides a composition which is a liquid at 20° C. after rising to that temperature from a lower temperature at which the oil was previously semisolid. The preferred edible oil is a medium-chain triglyceride oil, wherein the level of menthol in the composition is between 1-50% by total weight, so as to provide an menthol application rate of between 5 and 20 mg of menthol, and most preferably, about 10 mg menthol, in a single droplet of the composition. The composition can also include additional added vitamins and essential oils. A liquid method for administering menthol is provided. | 2015-12-17 |
20150359754 | METHODS AND DEVICES FOR USING ISOPERILLYL ALCOHOL - The present invention provides for a method of treating a disease such as cancer, comprising the step of administering to a patient a therapeutically effective amount of an isomer or analog of monoterpene or sesquiterpene (or its derivative), such as an isoperillyl alcohol. The present invention also provides for a method of treating a disease comprising the step of administering to a patient a therapeutically effective amount of a derivative of an isomer or analog of monoterpene or sesquiterpene, such as an isoperillyl alcohol carbamate. The derivative may be an isoperillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The route of administration may vary, including inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection. | 2015-12-17 |
20150359755 | USE OF CANNABINOIDS IN THE TREATMENT OF EPILEPSY - The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE). In particular, the disclosure relates to the use of CBD of treating TRE when the TRE is Dravet syndrome; myoclonic absence seizures or febrile infection related epilepsy syndrome (FIRES). The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs). | 2015-12-17 |
20150359756 | USE OF CANNABINOIDS IN THE TREATMENT OF EPILEPSY - The present disclosure relates to the use of cannabidiol (CBD) in the treatment of absence seizures. In particular, the disclosure relates to the use of CBD for reducing absence seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; CDKL5; Dup15q; Jeavons syndrome; Myoclonic Absence Epilepsy; Neuronal ceroid lipofuscinoses (NCL) and brain abnormalities. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs). | 2015-12-17 |
20150359757 | A METHOD FOR IMPROVING THE WELLBEING OF AN ANIMAL USING A COMPOSITION INCLUDING VITAMIN K - There is disclosed herein a method of improving the wellbeing, as herein defined, of an animal comprising administering to an animal an effective amount of a composition containing: vitamin K1, vitamin K2 or a mixture of vitamin K1 and vitamin K2, together with a physiologically acceptable carrier, excipient and/or diluent. | 2015-12-17 |
20150359758 | Method for treating or preventing radiation damage - Disclosed in the present invention is new use of saturated amine compounds for use in preparing medicines to resist radiation damage and promoting regeneration and repair of radiation-damaged tissues. | 2015-12-17 |
20150359759 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS - A method of treating a pervasive development disorder in a subject includes administering to the subject an amount of an NMDAR antagonist effective to ameliorate biochemical and functional abnormalities in the subject associated with loss-of-function mutations of the gene encoding methyl-CpG binding protein 2 (MeCP2). | 2015-12-17 |
20150359760 | LIPOLYTIC METHODS - Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally. | 2015-12-17 |
20150359761 | METHODS AND COMPOSITIONS FOR TREATMENT OF DEMYELINATING DISEASES - Disclosed herein are new oral pharmaceutical compositions of SAMDC inhibitors, polyamine analogs, and polyamine biosynthesis inhibitors, and their application for the treatment of conditions including demyelinating diseases, autoimmune disorders affecting the nervous system, and other neurodegenerative conditions. | 2015-12-17 |
20150359762 | COMPOSITION AND METHOD FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CEREBRAL INJURY - Methods and compositions which include or include the administration of a hydrophobic drug, prodrug thereof, salt thereof, isoform thereof, or a combination thereof; cyclodextrin, prodrug thereof, salt thereof, or a combination thereof; polyethylene glycol, propylene glycol, or combination thereof; and optionally, a pharmaceutically acceptable carrier. | 2015-12-17 |
20150359763 | USE OF 3-BROMOPYRUVATE AS A CONTRACEPTIVE - Disclosed herein are methods of inhibiting sperm motility. In some embodiments, a method of inhibiting sperm motility includes contacting a sperm with an effective amount of 3BP, thereby inhibiting sperm motility. Also disclosed herein are methods of contraception. In some embodiments, a method of contraception includes administering an effective amount of 3BP to the vagina so that sperm in contact with 3BP change their swimming patterns, which are incompatible with fertilization, thus preventing pregnancy. In one embodiment, a method includes topical application of 3BP to the penis in an amount effective to cause complete loss of motility of ejaculated sperm during sexual intercourse, thereby achieving contraception. In some examples, 3BP is administered as a spermicide in the forms of a jelly (gel), films, sponges, foams and timed-release mesh. In some examples, condoms are coated with 3BP-containing lubricant to achieve contraception. | 2015-12-17 |
20150359764 | METHODS OF TREATMENT USING 3-BROMOPYRUVATE AND OTHER SELECTIVE INHIBITORS OF ATP PRODUCTION - The present invention provides methods for preventing or treating infections, especially bacterial infections, by administering selective inhibitors of ATP production to inhibit glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase (GAPDH). As such, the present invention further provides methods for preventing or treating inflammation and sepsis associated with infections, as well as increased wound healing and decreased wound scarring. | 2015-12-17 |
20150359765 | METHODS OF MODULATION OF BRANCHED CHAIN ACIDS AND USES THEREOF - A method of modulating plasma levels of branched chain amino acids and branched chain alpha-keto acids is disclosed, wherein an ammonia scavenger compound or a salt thereof, for example phenylbutyrate or an even numbered congener thereof or a salt thereof, is administered to an individual in need thereof. In various methods, a decrease in plasma levels of branched chain amino acids and branched chain alpha-keto acids is effected to treat individuals suffering from an inborn error in metabolism of amino acids, such as Maple Syrup Urine Disease, for example. | 2015-12-17 |