49th week of 2013 patent applcation highlights part 45 |
Patent application number | Title | Published |
20130323072 | AXIAL FAN - The invention relates to an axial fan for delivering cooling air, in particular for an internal combustion engine of a motor vehicle, comprising fan blades which are fastened to a hub and which have a pressure side and a suction side and a trailing edge and a blade depth, on the pressure side of which fan blades is arranged a hub ramp which rises counter to the direction of rotation of the axial fan, wherein the trailing edge has an outer region situated radially outside the hub ramp and has an inner region situated radially within the hub ramp. | 2013-12-05 |
20130323073 | ASSEMBLED BLADE PLATFORM - A method of making a platform of a blade includes the steps of creating two platform sections by solidifying a material with a fabric in a mold and positioning a band of fabric around the two platform sections to retain an airfoil and define a blade. The method further includes the step of bonding the two platform sections together by solidifying the material to define a platform of a solid material. The platform is not bonded to the airfoil. | 2013-12-05 |
20130323074 | FRICTION WELDED TURBINE DISK AND SHAFT - An assembly for use in a turbine of a gas turbine engine includes a turbine disk and a shaft. The turbine disk comprises a superalloy. The shaft is friction welded to the turbine disk at a shaft interface substantially adjacent the turbine disk. | 2013-12-05 |
20130323075 | NICKEL-CHROMIUM-MOLYBDENUM-VANADIUM ALLOY AND TURBINE COMPONENT - A NiCrMoV alloy and a turbine component are disclosed. The NiCrMoV alloy includes at least about 0.06%, at least about 3.40% nickel, between about 0.22% and about 0.30% carbon, up to about 0.60% molybdenum, up to about 0.15% vanadium, up to about 2.00% chromium, up to about 0.012% phosphorus, up to about 0.007% sulfur, up to about 0.10% silicon, up to about 0.002% antimony, up to about 0.008% arsenic, up to about 0.012% tin, and up to about 0.015% aluminum and/or is resistant to embrittlement at temperatures above 700° F. | 2013-12-05 |
20130323076 | MARINE PROPELLER WITH AN ADJUSTABLE EXHAUST STRUCTURE - A marine propeller with an adjustable exhaust structure is disclosed. Each adjustable exhaust device of the adjustable exhaust structure includes an exhaust hole unit with exhaust through holes cut through the outer surface and inner surface of the propeller hub of the marine propeller, an adjustment member with shielding portions mounted in the exhaust hole unit, and a fastening member for securing the adjustment member in position. The adjustment member is movable to adjust the shielding area of the shielding portions relative to the exhaust through holes when disengaged from the constraint of the fastening member. Thus, the exhaust volume is adjustable to fit different conditions without changing any component parts of the marine propeller, facilitating ease of use of the marine propeller. | 2013-12-05 |
20130323077 | COMPRESSOR POWER AND TORQUE TRANSMITTING HUB - A compressor hub includes a sleeve portion, a cone portion, and a mounting flange portion. The sleeve portion is cylindrical about a sleeve axis. The frustoconical cone portion is attached to the sleeve portion and diverges radially outward. In addition, the cone portion includes an inner cone portion with an inner generatrix and an outer cone portion with an outer generatrix that is colinear with the inner generatrix. The mounting flange portion is attached to the outer cone for attaching a rotor disk to the compressor hub. | 2013-12-05 |
20130323078 | TURBINE BLADE ROOT WITH MICROCIRCUIT COOLING PASSAGES - A method of fabricating an airfoil includes the steps of fabricating a first core including a first plurality of ribs defining a first plurality of passages of a completed airfoil, and fabricating as second core including a second plurality of ribs defining a second plurality of passages of the completed airfoil. The second plurality of ribs includes a plurality of standoffs. The plurality of standoffs set a spacing between the first plurality of ribs and the second plurality of ribs to define a spacing between the first plurality of channels and the second plurality of channels of the completed airfoil. The airfoil is then molded about the core assembly. Once completed, the core assembly is removed to provide a completed airfoil incorporating multiple microcircuits with a desired stability and structural integrity. | 2013-12-05 |
20130323079 | TURBOMACHINERY COMPONENT COOLING SCHEME - A turbomachinery component includes a surface exposed to hot working fluid flow. The surface has an undulating contour formed from a series of alternating protuberances and troughs. A set of three cooling outlets is associated with each trough. | 2013-12-05 |
20130323080 | VORTEX GENERATORS FOR IMPROVED FILM EFFECTIVENESS - An airfoil includes a suction surface, a pressure surface, a first showerhead cooling hole and a second showerhead cooling hole. The suction surface and the pressure surface both extend axially between a leading edge and a trailing edge, as well as radially from a root section to a tip section. The first showerhead cooling hole and the second showerhead cooling hole both extend into pressure surface near the leading edge. The first showerhead cooling hole and the second showerhead cooling hole are angled in opposing directions. | 2013-12-05 |
20130323081 | TURBOPUMP - The invention relates to a field of feeding reaction engines, and in particular a turbopump | 2013-12-05 |
20130323082 | ANTI-SURGE SPEED CONTROL - The present invention relates to a method and control system to control the speed of a centrifugal compressor operating within a vacuum pressure swing adsorption process to avoid an operation at which surge can occur and directly driven by an electric motor that is in turn controlled by a variable frequency drive. In accordance with present invention an optimal speed for operation of the compressor is determined at which the compressor will operate along a peak efficiency operating line of a compressor map thereof. This speed is adjusted by a feed back speed multiplier when the flow or other parameter referable to flow through the compressor is below a minimum and a feed forward multiplier during evacuation and evacuation with purge steps that multiplies the feed back multiplier to increase speed of the compressor and thereby avoid surge. | 2013-12-05 |
20130323083 | CONVEYING UNIT FOR A REDUCING AGENT - A conveying unit for conveying reducing agent from a tank to an exhaust gas treatment device for treating the exhaust gases from an internal combustion engine, includes a pump having a drive or drive unit and a pump chamber unit or containment. The pump chamber unit or containment at least partly delimits a pump chamber and the drive or drive unit and the pump chamber unit or containment are detachable from one another. | 2013-12-05 |
20130323084 | Control Device And Pump Apparatus - This invention relates to programmable electronic device that prevents wastewater submersible and non-submersible pumps as well as viscous pumps from ragging therefore avoiding pump blockage. In one aspect the invention provides a pump apparatus comprising a pump and a control device for a pump, the pump being a mechanically switched pump such as a direct online/star delta pump and capable of being operated in a forward and a reverse direction, the control device comprising: a monitoring mechanism to monitor the torque of the pump, a control mechanism to control the direction of the pump and being capable of selectively directing the pump to (i) stop, (ii) operate in a reverse and (iii) operate in a forward direction; wherein the control mechanism is adapted to control the pump to do at least one of (a) stop and (b) operate in a reverse direction when the monitoring mechanism detects a pre-determined value in the torque of the pump. The device is programmed to provide anti-ragging functionality whilst providing traditional electrical pump protections. The physical size of the device has been minimised which enables great use and, significantly, retro-fitting of the product. | 2013-12-05 |
20130323085 | FLUID CONTROL APPARATUS AND METHOD FOR ADJUSTING FLUID CONTROL APPARATUS - In a method for adjusting a fluid control apparatus, in a pressing step, a piezoelectric pump is placed on a stage with a cover plate facing upward, the stage is moved up, and a center portion of a principal surface of the cover plate on a side opposite to a diaphragm is pressed with a pressing pin. As a result, the cover plate and the base plate are shaped so as to warp convexly toward the diaphragm side, and a portion joined to a flexible plate is pulled, such that the flexible plate is caused to warp convexly toward the diaphragm side. Thus, residual tensile stress occurs in a movable portion of the flexible plate. Therefore, due to the residual tensile stress, the tensile stress of the movable portion of the flexible plate is increased. | 2013-12-05 |
20130323086 | HYDRAULIC GRAVITY RAM PUMP - A piston type pumping apparatus comprises a vertically oriented cylinder having a top and a bottom with a first aperture. There are first and second passageways for liquid in the cylinder at the top and bottom respectively thereof. A piston is reciprocatingly mounted within the cylinder and has an area against which pressurized fluid acts in the direction of movement of the piston. A hollow piston rod is connected to the piston and extends below the piston and slidably through the first aperture. There is a reload chamber below the cylinder. The piston rod extends slidably into the reload chamber and has a third passageway for liquid communicating thereto. A first one-way valve is located in the third passageway. There is also a fourth passageway that extends from the reload chamber to a source of liquid to be pumped and a second one-way valve therein. | 2013-12-05 |
20130323087 | COMPRESSOR AND METHOD FOR COMPRESSING TECHNICAL GASES - The present invention relates to a compressor ( | 2013-12-05 |
20130323088 | Compressed Air Maintenance Unit and Consumer Control Device Equipped with the Same - A compressed air conditioning apparatus ( | 2013-12-05 |
20130323089 | ANNULAR JET PUMP - An annular ejector of an annular jet pump is coaxially arranged at a front of a central ejector. The annular ejector includes an annular nozzle, an annular mixing chamber, and an annular mixing duct. The central ejector includes a central nozzle, a central mixing chamber, and a central mixing duct. The annular nozzle is connected with a primary fluid inlet. A primary fluid inlet is in direct connection with the central nozzle arranged at a bottom of the central pipe, and a secondary fluid inlet is connected with a sidewall of the annular mixing chamber. | 2013-12-05 |
20130323090 | Valve Device having a Movement Element which is Cylindrical at least in Sections - A valve device has a movement element, which is cylindrical at least in sections, and a guide element, which has a guide recess for guiding the movement element and is pressed into a valve housing. The guide element comprises a radially inner ring-like section and a radially outer ring-like section. The guide recess is arranged in the inner ring-like section. On its outer circumference, the outer ring-like section has a number of contact sections which are arranged distributed uniformly over the circumference and by means of which the outer ring-like section is pressed into the valve housing. The inner ring-like section is connected to the outer ring-like section via an identical number of connecting sections, which are arranged distributed uniformly in the circumferential direction, wherein, as viewed in the circumferential direction, the connecting sections are offset radially by an angle of 180 DEG/N in relation to the contact sections. | 2013-12-05 |
20130323091 | Hydraulic System and Pressure Limiting Valve - A hydraulic system has at least one consumer and at least one hydraulic pump. A pressure limiting valve for limiting the maximum system pressure is connected with the at least one hydraulic pump, and the pressure limiting valve is pilot-controlled for switching a bypass. The invention also concerns a pressure limiting valve for limiting the system pressure inside such a hydraulic system. | 2013-12-05 |
20130323092 | Lighting System for Pedicure Spa - A light kit in combination with a pump system. The light kit includes a coil and a LED, where power produce by the coil when exposed to a rotating magnetic field powers the LEDs. The pump has a housing defining a pump interior, a driven magnet coupled to a pump impellor positioned in the pump interior, where the pump housing has an inlet and an outlet, and the is to be immersed in a fluid and to pump a fluid through the interior of the pump from the inlet to the outlet. | 2013-12-05 |
20130323093 | MOTOR AND FAN - A base plate of a motor includes an inner bottom plate portion and an elevated portion. A land portion is arranged on an upper surface of a portion of a circuit board which overlaps with the inner bottom plate portion in a plan view, or on a portion of the circuit board which overlaps with the elevated portion in the plan view. A conducting wire extending from a coil is electrically connected to the land portion. This structure enables the conducting wire to be connected to the land portion on the circuit board without the conducting wire being drawn outward beyond an outer circumferential end portion of the base plate. The axial position of the conducting wire connected to the land portion and the axial position of the base plate at least partially overlap with each other. | 2013-12-05 |
20130323094 | FAN MOTOR - Disclosed is a fan motor including: a lower bracket having a lower protruding portion disposed at the center thereof and a space portion formed around the lower protruding portion; an upper bracket having an upper protruding portion disposed at the center thereof; a rotor disposed between the lower protruding portion and the upper protruding portion in such a manner as to be rotated together with a shaft; a stator core adapted to be surrounded with a lower insulator disposed on the top of the lower protruding portion and with an upper insulator disposed on the underside of the upper protruded portion; and a PCB cover adapted to be coupled under the lower insulator in such a manner as to be disposed into the space portion of the lower bracket and having a PCB insertion space portion formed at the inside thereof. | 2013-12-05 |
20130323095 | OIL CIRCULATION SYSTEM FOR ELECTRIC MOTOR IN A HYBRID ELECTRIC VEHICLE - An oil circulation system for electric motors in a hybrid electric vehicle having, as a power source, an internal combustion engine is disclosed. Provision is made to start oil circulation under high reliability even though an electric pump cannot circulate lubricant oil through the electric motors due to increased viscosity at low temperatures. The oil circulation system includes the electric pump in fluid communication with an oil flow path for the electric motors; a mechanical pump, in fluid communication with the oil flow path, operable on driving power of the engine; and a controller for control of operation of the electric pump and that of the mechanical pump. The controller utilizes operation of the mechanical pump upon detection of abnormality in operation of the electric pump derived from viscosity of the lubricant oil in order to recover the electric pump. | 2013-12-05 |
20130323096 | DIAGONAL FAN - A diagonal ventilating fan ( | 2013-12-05 |
20130323097 | MOTOR-DRIVEN COMPRESSOR - A motor-driven compressor includes a housing made of a metal material, a compression portion, an electric motor, and a cover. The compression portion and the electric motor are accommodated in the housing, and the cover is attached to the housing. The cover is formed by a plastic portion and a shield made of a metal material that intercepts electromagnetic noise. A motor drive circuit for driving the electric motor is accommodated in an accommodation space defined by the housing and the cover. An elastic sealing member is located between the housing and the cover. The shield includes an extended portion that extends toward the housing and is arranged inside the sealing member. The extended portion is in contact with the housing. | 2013-12-05 |
20130323098 | AXIAL FLOW BLOWER - TECHNICAL PROBLEM | 2013-12-05 |
20130323099 | SYNTHETIC JET EQUIPMENT - A synthetic jet equipment is provided, including a base, a frame fixed to the base, a first member, a pump diaphragm, a second member, and a valve diaphragm. The pump diaphragm connects the first member to the frame, and the valve diaphragm connects the second member to the frame. The base, the frame, the first member, the pump diaphragm, the second member, and the valve diaphragm define a chamber forming an intake and an outlet. When the first member moves in a first direction, the second member moves in a second direction opposite to the first direction and the external air flows into the chamber through the inlet. When the first member moves in the second direction, the second member moves in the first direction, such that the air is exhausted from the chamber through the outlet. | 2013-12-05 |
20130323100 | FAN ASSEMBLY - A nozzle for a fan assembly includes an air inlet, an air outlet, an interior passage for conveying air from the air inlet to the air outlet, an annular inner wall, and an outer wall extending about the inner wall. The interior passage is located between the inner wall and the outer wall. The inner wall at least partially defines a bore through which air from outside the nozzle is drawn by air emitted from the air outlet. A flow control port is located downstream from the air outlet. A flow control chamber is provided for conveying air to the flow control port. A control mechanism selectively inhibits a flow of air through the flow control port to deflect an air flow emitted from the air outlet. | 2013-12-05 |
20130323101 | AIR COMPRESSOR UNIT - A volumetric reciprocating compressor comprises an air compressing unit equipped with a plurality of cylinders adapted to receive reciprocating pistons, a motor for driving the compressing unit and having a shaft which rotates about a respective axis of rotation, a cooling unit comprising a fan assembly driven by the rotating shaft to produce an air flow for cooling the compressed air in the unit, the cylinders being located inside an axisymmetric housing casing and being angularly spaced from each other. | 2013-12-05 |
20130323102 | GASEOUS FLUID COMPRESSION DEVICE - A gaseous fluid compression device includes: a first enclosure within which there is a movable first piston delimiting a first chamber and a second chamber; a second enclosure within which there is a movable second piston delimiting a third chamber and a fourth; a first exchange circuit connecting the first chamber and the fourth chamber, with a heat exchanger linked to a heat sink; a second exchange circuit connecting the second chamber and the third chamber, with a second heat exchanger linked to a heat source; and a transfer passage connecting the first chamber and the second chamber with an anti-backflow device. A back-and-forth movement of the interconnected pistons results in a compression of the gaseous fluid in the direction of the outlet. | 2013-12-05 |
20130323103 | SEAL ASSEMBLIES FOR RECIPROCATING AND ROTARY APPLICATIONS - Low-pressure and high-pressure reciprocating and rotary applications use seal assemblies to prevent leakage. One embodiment of a seal assembly includes a major annular body having opposing spaced-apart annular lips extending from a heel portion with a bore extending through the heel portion. A first spring is disposed between the lips, biasing the lips apart. A minor annular body extends from one of the lips of the major annular body. The minor annular body has opposing spaced-apart walls that extend from a base region and form a pocket. A second spring is disposed in the pocket between the spaced-apart walls, biasing the walls apart. During actuator operation, pressurized fluid urges one wall of the minor annular body against a pump head surface to produce a face seal and one of the lips of the major annular body against a rod surface to produce a radial seal. | 2013-12-05 |
20130323104 | SCAVENGE GEAR PUMP - A scavenge gear pump and its method of operation is described. The scavenge gear pump defines a pump chamber in which a pair of toothed gears are rotatably driven to pump an oil-air mixture from an inlet passage where the oil mixture is at low pressure, to an outlet passage where the air and oil has separated and is at high pressure. The gears are intermeshed in a meshing area between the inlet and the outlet passages and an oil nozzle is provided in a downstream region disposed in relation to the gear meshing area to inject oil under pressure in that area to occupy the volumes between the intermeshed gear teeth whereby to prevent air bubbles from being carried back to an upstream region adjacent the inlet passage. Accordingly, the volumetric efficiency of the pump is improved and it is more tolerant to back pressure. | 2013-12-05 |
20130323105 | THRUST PLATE FOR A HORIZONTAL SCROLL COMPRESSOR AND A HORIZONTAL SCROLL COMPRESSOR HAVING THE SAME - A thrust plate for a compressor may include first and second ends and a feed hole. The first end may include a thrust surface. The second end may include a lubricant accumulation feature. The feed hole may extend between the lubricant accumulation feature and the thrust surface to provide communication therebetween. The feed hole may be angled relative to a longitudinal axis of the thrust plate such that lubricant flows through the feed hole from the lubricant accumulation feature to the thrust surface. | 2013-12-05 |
20130323106 | ROTOR FOR OIL PUMP - A rotor for an oil pump according to the present invention is a rotor that includes an inner rotor configured by teeth, each of which has a plurality of ellipses or circles, and an outer rotor that is disposed on the outside of the inner rotor and has one tooth more than the inner rotor, wherein, in a tooth of the inner rotor, a tooth top and a tooth root of a drive-side half-tooth region extending from the tooth top to the tooth root and a tooth top and a tooth root of a non-drive-side half-tooth region extending from the tooth top to the tooth root are each configured by a different ellipse or a circle. A circumferential axis along a circumferential direction of the ellipse or circle configuring the tooth top is longer in the non-drive-side half-tooth region than in the drive-side half-tooth region. | 2013-12-05 |
20130323107 | SINTERED SUPERHARD COMPACT FOR CUTTING TOOL APPLICATIONS AND METHOD OF ITS PRODUCTION - A method and composition of a sintered superhard compact is provided. The sintered superhard compact body may comprise superhard particles and a binder phase. The binder phase may bond the superhard particles together. The binder phase comprises tungsten and cobalt. The ratio of tungsten to cobalt is between 1 and 2 and sum of W and Co in the sintered superhard compact is in a range of from about 2 to about 20 percent by weight. | 2013-12-05 |
20130323108 | INTERMETALLIC BONDED DIAMOND COMPOSITE COMPOSITION AND METHODS OF FORMING ARTICLES FROM SAME - An intermetallic bonded diamond composite composition and methods of processing such a composition are provided by the present invention. The intermetallic bonded diamond composite composition preferably comprises a nickel aluminide (Ni.sub.3Al) binder and diamond particles dispersed within the nickel aluminide (Ni.sub.3Al) binder. Additionally, the composite composition has a processing temperature of at least about 1,200.degree. C. and is processed such that the diamond particles remain intact and are not converted to graphite or vaporized by the high-temperature process. Methods of forming the composite composition are also provided that generally comprise the steps of milling, pressing, and sintering the high-temperature intermetallic binder and diamond particles. | 2013-12-05 |
20130323109 | RARE-EARTH BOND MAGNET MANUFACTURING METHOD - A method for producing a bonded rare-earth magnet according to an embodiment of the present invention includes the steps of: providing a rapidly solidified rare-earth magnet alloy powder; providing a solution in which a resin that is in solid phase at an ordinary temperature is dissolved in an organic solvent; mulling the rapidly solidified rare-earth magnet alloy powder and the solution together and vaporizing the organic solvent, thereby making a bonded rare-earth magnet compound in which magnet powder particles that form the rapidly solidified rare-earth magnet alloy powder are coated with the resin; making a compressed compact by compressing the bonded rare-earth magnet compound under a pressure of 1000 MPa to 2500 MPa; and thermally treating the compressed compact. If the rapidly solidified rare-earth magnet alloy powder to be mulled is 100 mass %, the solution includes 0.4 mass % to 1.0 mass % of the resin and 1.2 mass % to 20 mass % of the organic solvent. | 2013-12-05 |
20130323110 | P-TYPE SKUTTERUDITE MATERIAL AND METHOD OF MAKING THE SAME - The disclosure relates to a p-type skutterudite material and a method of making the same, comprising providing a p-type skutterudite material having a general formula: I | 2013-12-05 |
20130323111 | METHOD OF PRODUCTION OF RARE EARTH MAGNET - The present invention provides a method of production of a rare earth magnet which achieves high magnetization by hot working and at the same time secures high coercivity. | 2013-12-05 |
20130323112 | HOT-ROLLED STEEL SHEET AND METHOD OF PRODUCING THE SAME - In a hot-rolled sheet, an average value of pole densities of an orientation group {100}<011> to {223}<110>, which is represented by an arithmetic mean of pole densities of orientations {100}<011>, {116}<110>, {114}<110>, {112}<110>, and {223}<110> in a thickness center portion of a thickness range of ⅝ to ⅜ from a surface of the steel sheet, is 1.0 to 6.5 and a pole density of a crystal orientation {332}<113> is 1.0 to 5.0; and a Lankford value rC in a direction perpendicular to a rolling direction is 0.70 to 1.10 and a Lankford value r | 2013-12-05 |
20130323113 | NICKEL-CHROMIUM-IRON-ALUMINUM ALLOY HAVING GOOD PROCESSABILITY - The invention relates to a nickel-chromium-aluminum-iron alloy, comprising (in wt %) 12 to 28% chromium, 1.8 to 3.0% aluminum, 1.0 to 15% iron, 0.01 to 0.5% silicon, 0.005 to 0.5% manganese, 0.01 to 0.20% yttrium, 0.02 to 0.60% titanium, 0.01 to 0.2% zirconium, 0.0002 to 0.05% magnesium, 0.0001 to 0.05% calcium, 0.03 to 0.11% carbon, 0.003 to 0.05% nitrogen, 0.0005 to 0.008% boron, 0.0001 to 0.010% oxygen, 0.001 to 0.030% phosphorus, max. 0.010% sulfur, max. 0.5% molybdenum, max. 0.5% tungsten, the remainder nickel and the common contaminants resulting from the process, wherein the following relations must be satisfied: 7.7C−x·a<1.0, wherein a=PN if PN>0 or a=0 if PN≦0. Here, x=(1.0 Ti+1.06 Zr)/(0.251 Ti+0.132 Zr), PN=0.251 Ti+0.132 Zr−0.857 N, and Ti, Zr, N, and C are the concentration of the respective element in mass percent. | 2013-12-05 |
20130323114 | HIGH-STRENGTH COPPER ALLOY FORGING MATERIAL - The present invention relates to a high-strength copper alloy forging material having properties of high hardness, high strength and high thermal conductivity. | 2013-12-05 |
20130323115 | METHOD OF MANUFACTURING SILVER PLATELETS - The present invention provides an aqueous solution-based method for producing nano-sized silver platelets, which employs the controlled mixing of a silver ion solution, a reducing solution, and an acidic solution, under suitable conditions. Also provided are the silver platelets produced thereby, and compositions containing the silver platelets. | 2013-12-05 |
20130323116 | ALLOY MATERIAL WITH CONSTANT ELECTRICAL RESISTIVITY, APPLICATIONS AND METHOD FOR PRODUCING THE SAME - An alloy material with a constant electrical resistivity in a wide temperature range comprises the following chemical formula: Al | 2013-12-05 |
20130323117 | SYSTEMS AND METHODS TO MONITOR PROPER DISINFECTION OF NEEDLELESS CONNECTORS - A device and method for disinfecting a needleless connector, the device including a housing comprising a hub rotationally coupled to a motor, the motor being operably connected to a power source, the hub further comprising a receptacle configured to receive a cleaning head, wherein the device is configured to detect achievement of one or more minimum thresholds which are recommended to achieve proper disinfection of the needleless connector. Various devices and methods are further provided to permit tracking and reporting of disinfection events. | 2013-12-05 |
20130323118 | CONTAINER STERILIZATION APPARATUS AND METHOD - Provided is an apparatus for sterilizing containers with a conveying device, which conveys the containers along a pre-set conveying path. A first sterilization device acts upon at least one area of the containers with radiation in order to sterilize them. A checking device is arranged downstream with respect to the first sterilization device along the conveying path in order to check the sterilization procedure. The checking device is used for analyzing at least one medium occurring in the region of the containers. | 2013-12-05 |
20130323119 | SYSTEM AND METHOD FOR DISINFECTION OF MEDICAL DEVICES - An apparatus configured to disinfect an intravenous (IV) access port is disclosed. The apparatus has at least one sterilizing cap with a body configured to removably couple to the access port and an illuminator coupled to the body. The body and illuminator are configured to expose at least one surface of the access port to a dose of ultraviolet (UV) light. In certain embodiments, the illuminator includes a source of UV light, such as a light-emitting diode (LED). In certain embodiments, the illuminator receives the UV light from a remote source through a fiber-optic cable. | 2013-12-05 |
20130323120 | UV DISINFECTION SYSTEM FOR NEEDLELESS CONNECTOR - A device is presented for disinfecting needleless connectors. The device has a housing that contains a UV light source. The UV light source is operably connected to a power source. The housing has a receptacle configured to selectively receive a shield. The shield has an inner reflective chamber with an internal surface that reflects UV light. In use, the UV light source can illuminate a needleless connector inserted within the shield. | 2013-12-05 |
20130323121 | POLYESTER COMPOUNDS SUITABLE FOR HYDROCLAVING - A compound suitable for hydroclaving is disclosed, comprising polyester, polysulfone, and an epoxy-functional styrene-acrylate oligomer. In order for successful repetitious hydroclaving to be possible, the compound must also have a polysulfone content of greater than 45 weight percent of the compound. | 2013-12-05 |
20130323122 | CITRATE ANTICOAGULATION SYSTEM FOR EXTRACORPOREAL BLOOD TREATMENTS - A machine-readable medium with instructions for pumping blood from a patient's blood stream into an access line, introducing an anticoagulant solution into the pumped blood, filtering the pumped blood and delivering it to a return line, introducing a substitution fluid into the pumped blood, introducing a calcium and magnesium solution into the blood traveling through the return line, and returning the blood back to the patient's blood stream. | 2013-12-05 |
20130323123 | INTEGRATED TESTING DEVICE - An integrated testing device and method are disclosed. The device includes an integral reservoir for a test fluid, and an actuator, so that the test fluid can be dispensed to facilitate the test. | 2013-12-05 |
20130323124 | BIOLOGICAL SAMPLE MEASUREMENT APPARATUS - A biological sample measurement apparatus includes container ( | 2013-12-05 |
20130323125 | MEASUREMENT CHIP, MICROFLUIDIC DEVICE AND METHOD - A measurement chip ( | 2013-12-05 |
20130323126 | FLUID SENSING AND CONTROL IN A FLUIDIC ANALYZER - Instrument-cartridge interfaces for fluidic analyzers that have an instrument and a removable cartridge are disclosed. For example, and in one illustrative embodiment, the instrument may include a needle that is adapted to penetrate a septum on a removable cartridge. In another illustrative embodiment, the instrument may include a plunger that is adapted to deform a deformable membrane on a removable cartridge. In yet another illustrative embodiment, the instrument may include a nozzle that is adapted to mate and seal with a flow channel on a removable cartridge. Techniques for detecting the flow rate in a flow channel on a removable cartridge, as well as the position of fluid in a flow channel of a removable cartridge, are also disclosed. | 2013-12-05 |
20130323127 | SYSTEM FOR MONITORING PLANT EQUIPMENT - A system for monitoring plant equipment is provided. Another aspect provides an automated analysis system wherein software instructions operably compare sensor data to predefined valves and determine mechanical problems in multiple machines. In another aspect, a cement manufacturing system includes sensors for sensing movement conditions of cement making machines. A further aspect provides a central computer connected to vibration sensors associated with cement making machines, where software instructions perform real-time comparisons and machine performance determinations, based at least in part on sensed signals. | 2013-12-05 |
20130323128 | ULTRAVIOLET PHOTOREACTOR FOR THE PURIFICATION OF FLUIDS - In order to disinfect and to detoxify a fluid, a photoreactor contains at least two light sources. One light source activates the catalytic function of a semiconductor material in the fluid to reduce the concentration of contaminants in the fluid, such as by breaking down organic contaminants into non-toxic compounds. A second light source acts directly on living biological entities to sterilize or kill them and thereby disinfect the fluid, and can also serve to activate a semiconductor photocatalyst that in turn causes further damage to biological contaminants. The semiconductor photocatalyst is desirably attached to an optically transmitting fiber substrate in the fluid. The second light source in one embodiment is external to the fluid and illuminates the photocatalyst through transmitting surfaces in a fluid containment vessel. The light sources can comprise respective sets of plural LEDs. | 2013-12-05 |
20130323129 | SCAVENGING OXYGEN - A food container ( | 2013-12-05 |
20130323130 | EXHAUST PURIFICATION SYSTEM OF INTERNAL COMBUSTION ENGINE - An exhaust purification system in which when an air-fuel ratio of exhaust gas is leaner than a stoichiometric air-fuel ratio, a silver-alumina-based catalyst device releases adsorbed NO | 2013-12-05 |
20130323131 | EXHAUST PURIFICATION SYSTEM OF INTERNAL COMBUSTION ENGINE - In an internal combustion engine, inside of an engine exhaust passage, a hydrocarbon feed valve ( | 2013-12-05 |
20130323132 | RENEWABLE BLENDED NATURAL GAS AND ROCK WOOL PRODUCTION FROM A PLASMA-BASED SYSTEM - A method and system for augmenting the heat energy of a plasma torch in a gassifier using chemical energy, including the steps of injecting a fuel in the proximity of a plasma torch inside the gassifier chamber; and injecting an oxidant in the proximity of a plasma torch inside the gassifier chamber. As apparatus, an enhanced plasma gassifier arrangement is of the type that has a gassifier chamber having an electrically operated plasma torch for issuing a plasma discharge into the gassifier chamber. A fuel injection arrangement is disposed to surround the electrically operated plasma torch for injecting a fuel and an oxidant into the gassifier chamber. A natural gas inlet delivers natural gas into the gassifier chamber, thereby enhancing the temperature within the gassifier chamber. | 2013-12-05 |
20130323133 | Methods and Apparatus for Treating a Hydrocarbon Stream - Disclosed is an apparatus for treating two or more hydrocarbon feed streams. The apparatus according to one aspect includes a first feed line for supplying one aromatic feed stream and a second feed line for supplying another aromatic feed stream. The apparatus includes a juncture between the feed lines for combining the feed streams. The apparatus further includes a treatment zone in communication with the juncture for treating the combined feed stream. | 2013-12-05 |
20130323134 | Methods and Apparatus for Treating a Hydrocarbon Stream - Disclosed is an apparatus for removing water, nitrogen compounds, and unsaturated aliphatic compounds from a hydrocarbon feed stream including a water removal zone, a nitrogen removal zone, and an unsaturated aliphatic compound removal zone. By on aspect, the water removal zone includes a water selective adsorbent, the nitrogen removal zone includes a nitrogen selective adsorbent, and the unsaturated aliphatic compound removal zone includes an unsaturated aliphatic compound removal material. | 2013-12-05 |
20130323135 | Floating Catalyst/Regenerator - A fuel processor with a floating catalyst has a reactant gas passage and a product gas passage separated by a separating wall which is fixed at one end and free at the other end, to permit differential thermal expansion. The catalyst is received inside the separating wall proximate to the free end. An outer wall at least partially surrounds the separating wall and the fixed end of the separating wall may be joined to the outer wall. The fuel processor may comprise a plurality of concentric tubes, and may include a third tube located inside the separator wall. The gas passages are provided with gas permeable support structures such as turbulizers or fins which support the separating wall relative to the outer wall, but the support structures are bonded to only one tube in order to permit differential thermal expansion of the walls. | 2013-12-05 |
20130323136 | POWER SUPPLY ARRANGEMENT WITH AN INVERTER FOR PRODUCING A SINGLE-PHASE ALTERNATING CURRENT - Power supply arrangement with inverter ( | 2013-12-05 |
20130323137 | POWER SUPPLY ARRANGEMENT WITH AN INVERTER FOR PRODUCING N-PHASE AC CURRENT - A power supply arrangement (MF) with an inverter ( | 2013-12-05 |
20130323138 | SYSTEM FOR PERFORMING AUTOMATED SOLID PHASE EXTRACTIONS - The invention provides an improved instrument for automation of solid phase extraction chemistries typically used in biotechnology labs. The instrument includes a mechanism for transferring samples dissolved in a liquid from initial containers to reaction columns that are used to perform solid phase extractions. Samples, reaction columns and collection containers are in microtiter plate format or tubes that are on 18 millimeter centers. The transfer system is automatically cleaned after use in preparation for the next use. A dispense manifold is used to dispense various reagents into the reaction columns. Pressure differential is used to move reagents through reaction columns. A sliding cover is used to divert the reagent exiting reaction columns to waste or allowing collection of sample as it exits outlets of reaction columns. Samples are automatically collected in microtiter plates or in individual tubes or vials. | 2013-12-05 |
20130323139 | Pressurized Point-of-Use Superheated Steam Generation Apparatus and Method - Apparatus and method to produce point-of-use compressed superheated steam for a wide variety of uses including, but not limited to, cleaning, heating, drying, surface preparation, sterilization, pest control and elimination, degreasing and food preparation. The apparatus produces and compresses superheated steam without the hazards and problems associated with the current state of the art where steam is generated, compressed and stored in potentially dangerous and maintenance intensive boilers and associated piping and fixtures. The in-line steam generator of the present application produces superheated steam at one atmosphere which is immediately pressurized using a compression means and then immediately utilized through application employing a nozzle or a storage tank or other such device. | 2013-12-05 |
20130323140 | INTEGRATED PIPETTE TIP DEVICES - Disclosed herein are fluid handling devices that include integrated card and pipette tip devices, for use with multichannel liquid dispensing devices. | 2013-12-05 |
20130323141 | Density Phase Separation Device - A mechanical separator for separating a fluid sample into first and second phases within a collection container is disclosed. The mechanical separator may have a separator body having a through-hole defined therein, with the through-hole adapted for allowing fluid to pass therethrough. The separator body includes a float, having a first density, and a ballast, having a second density greater than the first density. A portion of the float is connected to a portion of the ballast. Optionally, the float may include a first extended tab adjacent a first opening of the through-hole and a second extended tab adjacent the second opening of the through-hole. In certain configurations, the separator body also includes an extended tab band disposed about an outer surface of the float. The separator body may also include an engagement band circumferentially disposed about at least a portion of the separator body. | 2013-12-05 |
20130323142 | METHOD FOR RECOVERING ACTIVE MATERIAL FROM WASTE BATTERY MATERIAL - Method of recovering active material from waste battery materials comprises: (1) an electrode material mixture recovery step of separating an electrode from the waste battery material to recover an electrode material mixture including the active material, a conductive material, and a binder from the electrode; (2) an activation agent mixing step of mixing an activation agent including one or more alkali metal compounds with the recovered electrode material mixture; (3) an activation step of heating the obtained mixture to a retention temperature not less than a melting start temperature of the activation agent to activate the active material included in the mixture; and (4) an active material recovery step of recovering the activated active material from a mixture obtained as a result of cooling after the activation step. | 2013-12-05 |
20130323143 | USING ALKALINE FLY ASH AND SIMILAR BYPRODUCTS IN AN ION-EXCHANGE/REVERSE OSMOSIS PROCESS FOR THE PRODUCTION OF SODIUM CARBONATE - The proposed invention uses industrial byproducts such as fly ash in an ion exchange/reverse osmosis (IE/RO) patented technology to sequester carbon dioxide CO2 gas and produce 6 to 7% sodium carbonate (Na | 2013-12-05 |
20130323144 | Apparatus, System and Method for Cleaning Air - An apparatus for cleaning air includes a housing having a chamber. The scrubber includes a carbon dioxide scrubber layer disposed in the chamber which claims carbon dioxide from air passing through the scrubber layer. The scrubber includes a forcing element which draws the air into the scrubber and forces the air through the scrubber layer which is powered without any electricity. A system for supporting a breathable environment for users. The system includes an enclosure. The system includes an air scrubber disposed in the enclosure which cleans carbon dioxide from air in the enclosure that is powered without any electricity. A method for cleaning carbon dioxide from air. The method includes the steps of flowing compressed air through a fluid driven motor to operate the motor without any electricity. There is the step of rotating a fan with the operating motor. There is the step of drawing air into a chamber of a housing with the fan blowing the air through a carbon dioxide scrubber layer of soda lime in the chamber, which scrubs the air of carbon dioxide, and out through an opening in the chamber above the layer. A cartridge for a scrubber. | 2013-12-05 |
20130323145 | Base Metal Catalyst Composition and Methods of Treating Exhaust From a Motorcycle - Aspects of the invention relate to a method of treating a gas stream generated by a motorcycle, the method comprising: contacting a gas stream containing hydrocarbons, carbon monoxide and nitrogen oxides and generated by a motorcycle under both rich and lean engine operating conditions with a base metal catalyst composition, thereby removing at least a part of the hydrocarbons, carbon monoxide and nitrogen oxides in gas stream. The base metal catalyst composition comprises a support including at least 10% by weight of reducible ceria, and about 3 to about 7 wt % MnO and about 8 to about 22 wt % CuO on the reducible ceria support. The base metal catalyst composition is effective to promote a steam reforming reaction of hydrocarbons and a water gas shift reaction to provide H | 2013-12-05 |
20130323146 | SMALL PORE MOLECULAR SIEVE SUPPORTED COPPER CATALYSTS DURABLE AGAINST LEAN/RICH AGING FOR THE REDUCTION OF NITROGEN OXIDES - A method of using a catalyst comprises exposing a catalyst to at least one reactant in a chemical process. The catalyst comprises copper and a small pore molecular sieve having a maximum ring size of eight tetrahedral atoms. The chemical process undergoes at least one period of exposure to a reducing atmosphere. The catalyst has an initial activity and the catalyst has a final activity after the at least one period of exposure to the reducing atmosphere. The final activity is within 30% of the initial activity at a temperature between 200 and 500° C. | 2013-12-05 |
20130323147 | CO2 RECOVERY SYSTEM AND METHOD | 2013-12-05 |
20130323148 | INTEGRATED CO2 PHASE CHANGING ABSORBENT FOR CO2 SEPARATION SYSTEM - A method and system for removing carbon dioxide from a power plant exhaust (such as a power plant, coal boilers, natural gas combined cycle plants or a gas turbine engine exhaust), where the method includes the steps of contacting the exhaust gas with a lean amino-silicone absorbent in an absorber, with the absorbent being sufficient in amount and concentration to react with a substantial portion of the carbon dioxide present in the exhaust gas; forming a liquid/solids slurry comprising unreacted amino-silicone absorbent and solid carbamates resulting from the reaction of the absorbent with carbon dioxide; heating the slurry in a desorber to a temperature sufficient to effectively strip the carbon dioxide from the carbamates; regenerating lean amino-silicone absorbent as a recycle stream back to the absorber; and sequestering the desorbed carbon dioxide gas. | 2013-12-05 |
20130323149 | IODINE ABSORBENT MATERIAL CONTAINING SALT AND RADIOACTIVE IODINE REMOVAL SYSTEM USING THE SAME - An apparatus for filtering airborne radioactive iodine is provided. The apparatus includes a housing defining an interior space and comprising an inlet for receiving air and an outlet for discharging the air; and a composition placed in the interior space for trapping airborne radioactive iodine between the inlet and the outlet. The composition comprises one or more salts selected from the group consisting of an alkali metal chloride and an alkaline earth metal chloride. A method of filtering airborne radioactive iodine is further provided. The method includes providing the foregoing apparatus at a nuclear facility and blowing air to flow from the inlet to the outlet and contact the composition placed in the interior space, whereby airborne radioactive iodine is trapped in the interior space. | 2013-12-05 |
20130323150 | METHOD OF FORMING HIGH-QUALITY HEXAGONAL BORON NITRIDE NANOSHEET USING MULTI COMPONENT EUTECTIC POINT SYSTEM - Provided is a method of manufacturing a hexagonal boron nitride nanosheet to mass-produce a high-quality hexagonal boron nitride nanosheet at a low temperature in a safe process. | 2013-12-05 |
20130323151 | MONOCHLOROSILANE, PROCESS AND APPARATUS FOR THE PREPARATION THEREOF - The invention relates to a process for preparing monochlorosilane by reaction of monosilane and dichlorosilane in the presence of a catalyst. In the process of the invention, monochlorosilane is formed by comproportionation of monosilane and dichlorosilane. The invention further relates to the use of the monochlorosilane produced and also a plant for carrying out the process. | 2013-12-05 |
20130323152 | READILY SINTERABLE SILICON CARBIDE POWDER AND SILICON CARBIDE CERAMIC SINTERED BODY - Provided are: a readily sinterable silicon carbide powder substantially having a stoichiometric composition and from which a dense sintered body can be obtained; a silicon carbide ceramic sintered body having a low specific resistance; and a production method thereof. This readily sinterable silicon carbide powder has a carbon/silicon elemental ratio of 0.96 to 1.04, an average particle diameter of 1.0 to 100 μm, and a ratio of 20% or less of an integrated value of an absorption intensity in a chemical shift range of 0 to 30 ppm to an integrated value of an absorption intensity in a chemical shift range of 0 to 170 ppm, in a | 2013-12-05 |
20130323153 | SILICON SINGLE CRYSTAL WAFER - The present invention provides a silicon single crystal wafer sliced out from a silicon single crystal ingot grown by a Czochralski method, wherein the silicon single crystal wafer is sliced out from the silicon single crystal ingot having oxygen concentration of 8×10 | 2013-12-05 |
20130323154 | PROCESS FOR PRODUCTION OF FLUOROSULFONYLIMIDE AMMONIUM SALT - A compound [I] such as ammonium N-(chlorosulfonyl)-N-(fluorosulfonyl)imide is reacted with hydrogen fluoride to obtain a compound [II] such as ammonium N,N-di(fluorosulfonyl)imide. The obtained compound [II] is reacted with an alkali metal compound or the like to obtain a compound [IV] such as an N,N-di(fluorosulfonyl)imide alkali metal salt. | 2013-12-05 |
20130323155 | PROCESS FOR PRODUCING FLUORINE-CONTAINING SULFONYLIMIDE SALT - By reacting a fluorine-containing sulfonylimide ammonium salt such as ammonium N,N-di(fluorosulfonyl)imide with an alkali metal hydroxide such as lithium hydroxide, potassium hydroxide or sodium hydroxide under reduced pressure and at a low temperature of approximately 40° C., a fluorine-containing sulfonylimide alkali metal salt such as lithium N,N-di(fluorosulfonyl)imide, potassium N,N-di(fluorosulfonyl)imide or sodium N,N-di(fluorosulfonyl)imide is obtained. | 2013-12-05 |
20130323156 | METHOD AND APPARATUS FOR SEQUENCING-BATCH PURIFICATION OF POTASSIUM NITRATE FROM SOLID WASTE PRODUCED BY GLASS-STRENGTHENING PROCESS - Provided is a method and an apparatus for purifying potassium nitrate from the solid waste produced by a chemical glass-strengthening process. In the method, the solid waste is melted into a liquid waste at first. Potassium nitrate of various purity grades can be obtained by batch processing the liquid waste through stepwise cooling processes of cooling the liquid waste to a first temperature facilitating the potassium nitrate contained in the liquid waste to be crystallized at a first rate and then cooling the liquid waste to a second temperature close to the freezing point of the potassium nitrate at a second rate that is slower than the first rate. The recovered potassium nitrate from the solid waste can be recycled and reused. | 2013-12-05 |
20130323157 | Apparatus and Methods for the Synthesis of Graphene by Chemical Vapor Deposition - An apparatus is provided for synthesizing a film on a substrate in a reactor that defines an outer reaction space. The apparatus comprises a vessel body and one or more vessel closures. The one or more vessel closures are adapted to be removably attached to the vessel body to form a reaction vessel therewith. The reaction vessel: i) comprises graphite; ii) defines an inner reaction space adapted to contain the substrate; iii) is adapted to be placed within the outer reaction space; and iv) is adapted to allow gas outside the reaction vessel to enter the inner reaction space. | 2013-12-05 |
20130323158 | Method of Laser Direct Synthesis of Graphene - A method of forming single and few layer graphene on a quartz substrate in one embodiment includes providing a quartz substrate, melting a portion of the quartz substrate, diffusing a form of carbon into the melted portion to form a carbon and quartz mixture, and precipitating at least one graphene layer out of the carbon and quartz mixture. | 2013-12-05 |
20130323159 | NOVEL GRAPHENE OXIDE REDUCING AGENT AND METHOD FOR PREPARING REDUCED GRAPHENE OXIDE USING THE SAME - An agent for reducing graphene oxide and a method for preparing reduced graphene oxide or graphene are provided. An agent for reducing graphene oxide include a mixture of a reducing agent containing a halogen element with trifluoroacetic acid (CF | 2013-12-05 |
20130323160 | CARBONATES AS RELIC PORE FORMERS IN ALUMINUM TITANATE - The disclosure relates to aluminum titanate-forming batch materials comprising inorganic batch components comprising at least one alkaline earth carbonate having a specified particle size distribution, methods of making ceramic bodies using the same, and ceramic bodies made in accordance with said methods. | 2013-12-05 |
20130323161 | METHOD OF MANUFACTURING HEXAGONAL FERRITE MAGNETIC POWDER AND ITS USAGE - An aspect of the present invention relates to a method of manufacturing hexagonal ferrite magnetic powder, which comprises preparing a melt by melting a starting material mixture comprising a hexagonal ferrite-forming component and a glass-forming component and rapidly cooling the melt to obtain a solidified product, heating the solidified product to precipitate hexagonal ferrite magnetic particles and glass components in the solidified product, subjecting the solidified product to an acid treatment following the heating to remove the glass components by dissolution, incorporating the hexagonal ferrite magnetic particles obtained following the acid treatment into an acidic aqueous solution, followed by separating the particles dispersed in the aqueous solution and the precipitated particles, and subjecting the precipitated particles to a cleaning treatment and then collecting the particles. | 2013-12-05 |
20130323162 | MEMBRANE REACTOR AND PROCESS FOR THE PRODUCTION OF A GASEOUS PRODUCT WITH SUCH REACTOR - The invention provides an integrated catalyst and membrane reactor for the production a predetermined gas such as hydrogen. The reactor comprises a gas flow channel, comprising a plurality of alternating catalyst sections and membrane sections, wherein each catalyst section comprises a catalyst bed and each membrane section comprises a plurality of membranes, and wherein the membranes are selectively permeable for the predetermined gaseous species. | 2013-12-05 |
20130323163 | METHOD FOR PRODUCING TITANO-(SILICO)-ALUMINO-PHOSPHATE - The invention relates to a method for producing titano-(silico)-alumino-phosphate, a catalyst shaped body which contains titano-(silico)-alumino-phosphate, a washcoat containing titano-(silico)-alumino-phosphate, the use of the washcoat to produce a catalyst by coating a support body, and to the use of titano-(silico)-alumino-phosphate or of the catalyst shaped body to produce a catalyst. | 2013-12-05 |
20130323164 | CHA-type Zeolite Materials and Methods for Their Preparation Using Cycloalkyammonium Compounds - Aspects of the present invention relate to a process for the preparation of a zeolitic material having a CHA-type framework structure comprising YO | 2013-12-05 |
20130323165 | Magnetic Nanoplatforms for Theranostic and Multi-Modal Imaging Applications - Disclosed are nanoparticle compositions comprising paramagnetic particles, radiolabels, fluorophores, and/or positron emission tomography agents encapsulated within a biocompatible vehicle. In addition, methods of multi-modal diagnostic imaging and treating diseased tissues are disclosed, wherein the methods comprises administering a nanoparticle composition to a subject in which the nanoparticle composition comprises paramagnetic particles, radiolabels, fluorophores, and positron emission tomography agents encapsulated within a biocompatible vehicle. | 2013-12-05 |
20130323166 | Radiation Therapy for Treating Alzheimer's Disease - A method treating dementia of the Alzheimer's type in a patient by administering ionizing radiation to the brain of the patient. | 2013-12-05 |
20130323167 | DETECTING AND TREATING SOLID TUMORS THROUGH SELECTIVE DISRUPTION OF TUMOR VASCULATURE - Several agents capable of inducing vascular responses akin to those observed in inflammatory processes enhance the accumulation of nanoparticles in tumors. Exemplary vascular-active agents include a bacterium, a pro-inflammatory cytokine, and microtubule-destabilizing drugs. Such agents can increase the tumor to blood ratio of radioactivity by more than 20-fold compared to nanoparticles alone. Moreover, vascular-active agents dramatically improved the therapeutic effect of nanoparticles containing radioactive isotopes or chemotherapeutic agents. | 2013-12-05 |
20130323168 | AGENTS AND METHODS FOR VISUALIZING ANALYTES - Provided herein are novel compounds based on xanthene, for example biarsenical compounds, which are useful as molecular probes. The compounds contain at least one isotope atom, such as a radioisotope atom. Methods for visualizing tetracysteine-tagged analyte molecules such as proteins using said compounds, methods for synthesizing said compounds, and methods for treating cancer or other hyperproliferative disorders using said compounds are also provided. | 2013-12-05 |
20130323169 | THIOL-ENE CLICK CHEMISTRY FOR DRUG CONJUGATES - The present invention relates to linker molecules that readily conjugate cellular recognition ligand at one end and drug payload at the other, and are useful in treating or preventing cancer, an autoimmune disease, an inflammatory condition, a central nervous system disorder or an infection. The linker inker molecules of the invention are represented by Formula I, II and III; Linker-Drug compounds represented by Formula IV, V and VI; and Ligand-Linker-Drug conjugates represented by Formula VII, VIII and IX: | 2013-12-05 |
20130323170 | PROSTHETIC GROUPS ATTACHED TO STANNYL POLYMER IN THE SYNTHESIS OF RADIOPHARMACEUTICALS - The present invention relates to compositions and methods for preparing radiopharmaceutical compounds in high chemical-purity and isotopic-purity. The present invention provides polymer-bound precursors to radiopharmaceutical compounds that can be converted to radiopharmaceutical compounds in one step. In a preferred embodiment, a radiopharmaceutical precursor is bound to a polymeric support via a prosthetic group comprising an alkenyl-tin bond. The radiopharmaceutical precursor is converted to a radiopharmaceutical compound in one step involving cleavage of the alkenyl-tin bond and incorporation of a radioisotope to form the radiopharmaceutical compound. Importantly, the polymeric support containing the toxic tin by-product can be easily removed from the radiopharmaceutical compound by filtration. The present invention can be used to install a large number of different radioisotopes. In a preferred embodiment, the radioisotope is | 2013-12-05 |
20130323171 | RADIOLABELED BBN ANALOGS FOR PET IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTORS - Radiolabeled bombesin (BBN) analogs that bind to the gastrin-releasing peptide receptor (GRPR) represent a topic of active investigation for the development of molecular probes for positron emission tomography (PET) or single-photon emission computed tomography (SPECT) of prostate cancer (PCa). RM1 and AMBA have been identified as the two most promising BBN peptides for GRPR-targeted cancer imaging and therapy. In this study, to develop a clinically translatable BBN-based PET probe, we synthesized and evaluated | 2013-12-05 |