38th week of 2013 patent applcation highlights part 50 |
Patent application number | Title | Published |
20130244186 | Composition And Method For Removing Photoresist And Bottom Anti-Reflective Coating For A Semiconductor Substrate - A composition for removing photoresist and bottom anti-reflective coating from a semiconductor substrate is disclosed. The composition may comprise a nontoxic solvent, the nontoxic solvent having a flash point above 80 degrees Celsius and being capable of dissolving acrylic polymer and phenolic polymer. The composition may further comprise Tetramethylammonium Hydroxide (TMAH) mixed with the nontoxic solvent. | 2013-09-19 |
20130244187 | HIGH EFFICIENCY LOW NOx EMISSION BURNER APPARATUS - A high efficiency low NO | 2013-09-19 |
20130244188 | OXYGEN TO EXPAND BURNER COMBUSTION CAPABILITY - A burner at which fuel cannot be combusted with air as the only source of oxygen for combustion in a stable flame at the burner when the feed rate of the fuel is too low, when the fuel is fed at too high an air-to-fuel mass ratio, when the fuel contains too high an amount of inert matter, or when the specific energy content of the fuel is too low, is modified by supplying oxidant containing more than 21 vol. % oxygen into the base of a flame at the burner, whereupon such fuels can be combusted at the burner. | 2013-09-19 |
20130244189 | OXYGEN TO EXPAND BURNER COMBUSTION CAPABILITY - A burner at which fuel cannot be combusted with air as the only source of oxygen for combustion in a stable flame at the burner when the feed rate of the fuel is too low, when the fuel is fed at too high an air-to-fuel mass ratio, when the fuel contains too high an amount of inert matter, or when the specific energy content of the fuel is too low, is modified by supplying oxidant containing more than 21 vol. % oxygen into the base of a flame at the burner, whereupon such fuels can be combusted at the burner. | 2013-09-19 |
20130244190 | OXYGEN COMBUSTION SYSTEM AND METHOD FOR OPERATING SAME - An oxygen combustion system includes a boiler to burn fuel using combustion gas composed of oxygen-rich gas and circulating flue gas, a dust remover disposed in a flue through which flue gas discharged from the boiler flows, a second flue leading the combustion gas to the boiler, the combustion gas being made by mixing the circulating flue gas extracted downstream of the dust remover with the oxygen-rich gas, a combustion gas heater exchanging heat between the flue gas flowing between the boiler and dust remover and the combustion gas flowing through the second flue, and a flue gas cooler disposed between the heater and the dust remover to cool the flue gas. A control unit controls at least one of a flow rate and cooling medium temperature of the flue gas cooler such that temperature of the flue gas introduced into the dust remover will be between 90° C. and 140° C. | 2013-09-19 |
20130244191 | Lighter Eyez - A combination cigarette lighter and eye-drop applicator wherein the eye-drop device is secured to the lighter by being press fit secured with plastic clips or secured by hollow housing, a reservoir in the housing adapted to hold a supply of eye-drops and a squeeze bottle for applying the eye-drops in addition to the fire-lighting section of ordinary lighters, such that a person could ease eye irritation and redness due to smoke or allergies without needing anything but a lighter. | 2013-09-19 |
20130244192 | MAGNETIC SENSOR MANUFACTURING - A magnetic sensor comprising a first shield and a second shield and a sensor stack between the first and the second shield, the sensor stack having a plurality of layers wherein at least one layer is annealed using in-situ rapid thermal annealing. In one implementation of the magnetic sensor a seed layer is annealed using in-situ rapid thermal annealing. Alternatively, one of a barrier layer, an AFM layer, and a cap layer is annealed using in-situ rapid thermal annealing. | 2013-09-19 |
20130244193 | System and Method for Orthodontic System - An orthodontic fixture system includes a tap, a screw, a tool, and fixation wire. In a method of orthodontic fixation, a user manipulates the tool to drive the tap and screw. The tap is configured to first make a threaded hole in only a proximal wall of an alveolus bone. The screw is configured for firm insertion in the proximal wall of the alveolus bone through the hole made with the tap and to abut an inner surface of the distal wall of the alveolus bone in a non-damaging manner. The screw and fixation wire include cooperating structures to enable a user to readily apply both tension and torsional forces via mutual engagement of the screw and fixation wire and thus to one or more orthodontic elements attachable to patient teeth. | 2013-09-19 |
20130244194 | ORTHODONTIC APPLIANCE, A SYSTEM AND A METHOD FOR AUTOMATICALLY STRAIGHTENING TEETH - An apparatus, a system and a method provide automatic tooth straightening. An appliance may be placed on teeth to straighten teeth. The appliance or series of appliances may be made to fit a particular patient. A portion of the appliance may be attached to fully erupted teeth that are substantially straight. The appliance may fit onto the teeth that do not require straightening using a section that may be made from relatively stiff material. The erupted teeth that require straightening may be straightened with a softer more resilient material. The unerupted teeth may be guided into the mouth by another portion of the appliance that is preformed with predicted sizes and shapes of teeth determined from sizes of other erupted adult teeth and shapes from anatomical standards. A hard stiffer inner shell and/or a stiffer isthmus having a softer material is overlayed to directly contact the teeth. | 2013-09-19 |
20130244195 | ORTHODONTIC APPLIANCE - An orthodontic appliance | 2013-09-19 |
20130244196 | METHOD AND DEVICE FOR REDUCING ANGULATION ERROR DURING DENTAL PROCEDURES - A device for reducing angulation error during the placement of dental implants or other dental procedures comprising two or more than two sensors that monitor realtime orientation of the device in space. A system for reducing angulation error during dental procedures, such as during the placement of dental implants or other dental procedures comprising the device and further comprising a dental handpiece. A method for reducing angulation error during the placement of dental implants or other dental procedures. | 2013-09-19 |
20130244197 | Dental Shade Matching Device - A non-contact type dental shade matching device is provided, comprising a camera body for capturing image of one or more target teeth; an opaque intra-oral compartment snugly adapted for a human mouth; an opaque cover shield body connected between the camera body and the intra-oral compartment; one or more holders for holding one or more shade tabs; and a color matching module being operably connected to the camera body to receive the captured images containing color and translucency information of the target tooth and/or shade tab information, and then to process the images based on a content-based algorithm for automatic shade matching between the target tooth and the shade tabs for each of the captured images, so as to achieve an optimal dental prosthesis. | 2013-09-19 |
20130244198 | Device for Recording a Bipupillary Axis - A device is disclosed for recording a specific horizontal reference line of a patient that enables the alignment of an upper jaw model to this horizontal reference line. The device serves not only to determine the horizontal reference line with the active communicative aid of the patient but also comprises a bite fork, which can be aligned in accordance with the description and can also be provided by this means. The adjusted bite fork may then be inserted into an articulator and may be fixed in place so that the model of the upper jaw is mounted parallel to the horizontal reference line of the patient. | 2013-09-19 |
20130244199 | Contrast Pattern Application For Three-Dimensional Imaging - Provided herein are compositions for applying a reference marker pattern or grid to the surface of an object to be imaged three-dimensionally. These compositions can be quick drying for ease of use. Methods of use of the compositions are also provided as well as devices and kits for the application of the compositions. | 2013-09-19 |
20130244200 | INSTRUMENT FOR DRILLING DENTAL ROOT CANALS - An instrument for drilling dental root canals, includes a tapered rod having on at least an active part of its length, at least one helical flute defining at least one helical cutting edge. The instrument also has a helical hollow on a portion of the active part extending as far as the point of the rod. At least one of the edges defined by the helical hollow is coincident with the cutting edge, the hollow reducing the cutting angle of the cutting edge. Any cross-section of the active part has at least one convex side belonging to the helical flute. The closer the cross-section in question is to the point of the rod, the more the curvature at any point of the convex side increases and tends to approximate the curvature of the circumscribed circle of the cross-section and passing via the cutting edge defined by the helical flute. | 2013-09-19 |
20130244201 | Universal Dental Elevator - A dental elevator for elevating, or loosening a tooth, portion of a tooth, or implant from any position in a mouth. Extending from one handle of the elevator in accordance with this invention is a hook shaped member terminating in a curved sharp edge for engaging the side of a tooth to be elevated or loosened. Extending from the other handle of the elevator in accordance with this invention is a pad, rotationally supported from the handle. The axis about which the pad may rotate 360 degrees is perpendicular both to the major axis of the handle and the plane in which the handles of the pliers lay. By providing two elevators which are mirror images of each other, a tooth, portion of a tooth, or implant may be elevated or loosened from any position within a mouth. | 2013-09-19 |
20130244202 | QUICK DENTAL IMPLANT KIT - A quick dental implant kit includes a fixture having an upper fine thread portion, a lower coarse thread portion and a diameter gradually reducing in direction from the top side toward the bottom side and exhibiting a long arc-shaped contour, and a drill bit having a shank connectable to and rotatable by a dental handpiece and a stepped cutter body formed integral with the bottom end of the shank and defining a plurality of stepped cutting edges for drilling a stepped hole in a jawbone of a patient for the implant of the fixture. Each stepped cutting edge defines at least five steps and at least four risers alternatively connected in a longitudinal series to fit the long arc-shaped contour of the fixture. | 2013-09-19 |
20130244203 | DENTAL COMPONENT, A DENTAL FIXTURE AND A DENTAL IMPLANT - The invention relates to a dental component, such as an abutment, an abutment replica, an abutment blank, a customized abutment, a scan abutment, a digital transfer coping, an impression pick-up element, a healing cap or a driver, comprises at least one first indexing element and at least one second indexing element having an apical end located apically of the apical end of said first indexing element, wherein the second indexing element is designed to present a play with mating features of a dental fixture. The invention also relates to a dental implant which comprises a dental component having first and second indexing elements and a dental fixture having third and fourth indexing elements, wherein any play between the first and third indexing elements is smaller than a play between the second and fourth indexing elements. The invention also relates to a dental fixture. | 2013-09-19 |
20130244204 | DENTAL COMPONENT AND A DENTAL IMPLANT - The invention relates to a dental component, such as an abutment, an abutment replica, an abutment blank, a customized abutment, a scan abutment, a digital transfer coping, an impression pick-up element, a healing cap or a driver, comprises a first indexing element and at least two second indexing elements having apical ends located apically of the apical end of said first indexing element. The invention also relates to a dental implant which comprises a dental component having first and second indexing elements and a fixture having third and fourth indexing elements, wherein the first and third indexing elements can only engage with each other after the second and fourth indexing elements have engaged with each other. The invention also relates to a fixture. | 2013-09-19 |
20130244205 | Method For Pre-Operative Visualization Of Instrumentation Used With A Surgical Guide For Dental Implant Placement - The invention relates to manufacturing a surgical guide to be placed in a patient's mouth. The patient's mouth is scanned to obtain surgical-region scan data at a region where an implant is to be located. The patient's mouth is also scanned in the opened position to acquire dental conditions opposite from the surgical region so as to obtain opposing-condition scan data. A virtual model is developed using the surgical-region scan data and the opposing-condition scan data. Using the virtual model, a surgical plan is developed that includes the location of the implant to be installed in the patient. A virtual surgical guide is also developed based on the surgical plan. The dimensions of instrumentation to be used with the surgical guide are checked to ensure they will fit within the mouth by use of the opposing-condition scan data. After checking, final surgical-guide manufacturing information is obtained for manufacturing the surgical guide. | 2013-09-19 |
20130244206 | PATIENT-SPECIFIC SYSTEM FOR RESTORING MISSING DENTITION - A patient-specific system for restoring missing dentition may include surgical components including a dental implant drilling guide adapted to the patient's dental anatomy, dental implant, drills required to place said implant, and drilling depth and sequence instructions specific to the patient. Further, the system includes a patient-specific healing abutment to form a customized emergence profile, an impression coping with the same emergence profile, a provisional abutment with the same emergence profile, a final abutment with the same emergence profile, a provisional crown or bridge, and a final crown or bridge. The crown or bridge may be screw or cement retained. | 2013-09-19 |
20130244207 | Mold For Dental Copings And Copings Produced By Using The Mold - A mold for producing a coping used in a dental implant includes a male component having a protrusion and a female screw forming part. The mold further includes a female component having a recess and a male screw forming part having a different rotation direction from that of the female screw forming part. A cavity for producing the coping is formed by combining the male and female components. Since the mold includes a male component having a female screw forming part, and a female component having a male screw forming part with a different rotation direction than the female screw forming part, a produced coping may be easily separated from the male and female components. | 2013-09-19 |
20130244208 | CUSTOMIZED DENTAL PROSTHESIS FOR PERIODONTAL OR OSSEOINTEGRATION, AND RELATED SYSTEMS - A dental prosthesis to be integrated into a jaw bone cavity of a pre-identified patient. An example of a dental prosthesis includes a first manufactured portion having a surface shaped to substantially dimensionally conform three dimensionally to an undersized shape of the outer three-dimensional surface shape of a root of a tooth to be replaced, and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of the tooth. The outer surface of the root portion can include or be coated with a biocompatible material that is suitable to be integrated into the extraction socket and adopted by existing tissue forming the socket. | 2013-09-19 |
20130244209 | PLASTIC IMPLANT ANALOG - An implant analog for use in dental procedures has a plastic member which has a central bore. A metal insert which has a female thread is located in the central bore. The outer surface of the metal insert has a series of projections which lock the metal insert and the plastic body and prevent relative rotation or axial motion between the metal insert and the plastic member. | 2013-09-19 |
20130244210 | In-Car Driver Tracking Device - Disclosed are a device and method for providing driver tracking and behavior analysis, initiated without concurrent user input, by the presence detection of one or more drivers of the vehicle. Vehicle motion inferred from a location aware device sensor, as well as other driver smartphone sensors and application use are logged and analyzed to determine risk factors associated with identified drivers. Internet data sources are further utilized for associating road conditions and traffic regulations with the logged locations of the vehicle. Logged and analyzed data from the identified drivers is aggregated for reporting on vehicle risk. | 2013-09-19 |
20130244211 | SYSTEMS AND METHODS FOR MEASURING, ANALYZING, AND PROVIDING FEEDBACK FOR MOVEMENT IN MULTIDIMENSIONAL SPACE - The present invention provides systems and methods that measure and analyze a user's movement during a specific activity, then provide immediate, focused feedback as to how the user can modify the movement. | 2013-09-19 |
20130244212 | ON-LINE SYSTEM FOR GENERATING INDIVIDUALIZED TRAINING PLANS - The internet based training system creates an individualized training plan designed to achieve a particular training purpose and delivers the plan to the individual user or athlete via the internet. The training system includes a local user interface and a remote server accessed via the internet. The remote server includes a computer program and a number of databases containing team information, athlete information, exercise information and training programs associated with specific training purposes such as a specific sport or activity. An algorithm is used for determining the weight of each exercise to be performed for each period in the training cycle of a particular training program. The computer program automatically creates a specific training plan using information from the databases and the weight determined by the algorithm. | 2013-09-19 |
20130244213 | Instructional quick connect shoelaces, a fashionable shoelace tying system utilizing multiple sensory inputs via interchangeable, unique half shoelaces attached with a quick connect buckle - A quick connect shoelace with interchangeable half lace section. | 2013-09-19 |
20130244214 | BONE AUGMENTATION TRAINING SYSTEM - The disclosed apparatuses, methods, and systems provide for simulations of real-life bone graft procedures. One embodiment is a model that includes a base in the shape of at least a portion of a maxillary or mandibular dental arch, and includes a defect on its surface. The model also includes a multi-layer tissue model configured to overlay at least a portion of the base in a covering relationship with the defect and surrounding tissue. The multi-layer tissue model includes a gingival simulating layer, connective tissue simulating layer, and two adhesive layers. The first of the two adhesive layers connects the connective tissue simulating layer to the gingival simulating layer, and the second adhesive layer, affixed to the connective tissue simulating layer opposite the first layer, is configured to adhere the multi-layer tissue model to the base. The multi-layer tissue model also includes a removable backing covering the second adhesive layer. | 2013-09-19 |
20130244215 | OPERATING DEVICE AND GUIDING LEARNING METHOD FOR EARLY EDUCATION - An operating device for early education is provided. The operating device includes an operating console comprising a plurality of various keyboards around an edge of the operating console used for receiving keystrokes, a data transceiver used for transmitting encoding information corresponding to keystrokes to a portable device and receiving activation controlling information from the portable device used for activating a keyboard, and a plurality of controlling keys used for receiving selection controlling information and transmitting the selection controlling information to the portable device by the data transceiver. Advantageously, the operating device includes a plurality of various keyboards that is independent of the portable device, which is convenient for children's operation/input. Additionally, a plurality of various keyboards are provided, advantageously, more learning content interacted by means of the various keyboards can be provided by the application programs via the portable devices. | 2013-09-19 |
20130244216 | Pop-up Content for Figurative Expressions and Complementary Related Trivia - An educational and fun computer process in which a user selects a figurative expression displayed on a screen. The figurative expressions are, for example, metaphors, allusions, puns, double entendres, anagrams, cropped terms, and other nonliteral terms. A pop-up space instantly appears that presents educational content about the figurative expression. A complementary related trivia is presented in various possible formats to enliven the learning experience. The complementary trivia can be related to the figurative expression, or the associated information displayed on the screen, or the educational content, or the trivia itself. The educational content can be, for example, meanings, reference materials, literary reviews, interpretations, and images or moving images. The reference materials are, for example, dictionary entries like definitions, senses, parts of speech, antonyms, and etymologies. The educational features are options used to help a person learn about figurative expressions, and the entertaining trivia is there to be enjoyed. | 2013-09-19 |
20130244217 | TABLET LEARNING APPARATUS - One embodiment of the invention is directed to a method comprising electronically providing content to a user via a display on a learning apparatus wherein the content comprises a plurality of stationary image elements and a plurality of removable image elements at a plurality of locations on the display, detecting when a user shakes the learning apparatus, wherein the removable image elements move away from the plurality of locations, receiving an indication that one or more of the image elements has been selected by a user, and determining a location of placement of the one or more image elements by the user. | 2013-09-19 |
20130244218 | EDUCATIONAL SYSTEM EMPLOYING VIRTUAL ENVIRONMENTS - An educational system consists of developing a virtual environment accessible by students and teachers through video game-like experiences. Each of the teachers and students is assigned an avatar that is uniquely controlled by the associated student or teacher. The students manipulate their avatars within the virtual environment, resolving issues, solving problems, and learning along the way. Each student has a student portfolio indicating the student's progress and deficiencies as assessed by the student's activities through the avatar in the virtual environment. A virtual learning core communicates with remote educational organizations having virtual environments and is in selective communication with each. The virtual learning core includes a database for receiving, storing, assessing and transferring data and student and teacher interface modules in interconnection with the database to allow communication among students and with a teacher within the virtual environments. | 2013-09-19 |
20130244219 | STUDENT PROFILE GRADING SYSTEM - The invention relates to a method and means of grading students. This invention is a software application utilizing profiling techniques that when combined or imbedded with available knowledge on the human learning experience will individually evaluate each student based on their current ability and capacity to learn, by subject. Student's tests are graded electronically against their personal ability and capability profile for grade. The profile system software is applicable to many learning situations requiring a measured outcome. | 2013-09-19 |
20130244220 | METHOD OF OPERATION OF FERMENTATION OF CARBON MONOXIDE AND HYDROGEN CONTAINING GASEOUS SUBSTRATE - A method of gaseous substrate fermentation comprising: adding gaseous substrate comprising carbon monoxide (CO) and hydrogen (H | 2013-09-19 |
20130244221 | METHOD FOR ISOLATING HEPATITIS A VIRUS OR SPRING VIREMIA OF CARP VIRUS - A method for isolating Hepatitis A virus or Spring viremia of Carp virus. A virus probe is prepared by linking a magnetic bead-conjugated Protein G with an anti-HAV (Hepatitis A Virus) antibody or an anti-rhabdovirus antibody. The virus probe is contacted with a sample to be analyzed to form a virus probe-virus complex. The virus probe-virus complex is then isolated. It may specifically isolate Hepatitis A virus or Spring viremia of Carp virus from a sample mixed viruses. | 2013-09-19 |
20130244222 | LIPOPARTICLES COMPRISING ION CHANNELS, METHODS OF MAKING AND USING THE SAME - The present invention relates to the use of lipoparticles, virus-like particles, and viruses. The present invention also relates to testing ion channel function and modulators of ion channels. | 2013-09-19 |
20130244223 | RESPIRATORY SYNCYTIAL VIRUS (RSV) VIRAL LOAD DETECTION ASSAY - The invention concerns a method for the extraction of nucleic acids from biological samples e.g. tissue material or sputum derived from human or animal species and the quantitative detection thereafter of said nucleic acids e.g. in terms of viral load, more specifically RSV viral load detection. | 2013-09-19 |
20130244224 | ENDOTOXIN DETECTION METHOD - The invention relates to a method for detecting endotoxins in a sample. | 2013-09-19 |
20130244225 | MICROORGANISM CONCENTRATION PROCESS AND DEVICE - A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising (1) a porous fibrous nonwoven matrix and (2) a plurality of particles of at least one concentration agent that comprises diatomaceous earth, the particles being enmeshed in the porous fibrous nonwoven matrix; (b) providing a sample comprising at least one target cellular analyte; (c) contacting the concentration device with the sample such that at least a portion of the at least one target cellular analyte is bound to or captured by the concentration device; and (d) detecting the presence of at least one bound target cellular analyte. | 2013-09-19 |
20130244226 | VIRUS DETECTION DEVICE AND VIRUS DETECTION METHOD - A virus detection device includes a diffusion unit configured to diffuse a virus in a gas as an inspection target into an aqueous solution containing a fluorescent antibody specifically adsorptive to the virus by bringing the gas into contact with the aqueous solution and configured to adsorb the fluorescent antibody to the virus in the gas; an atomization unit configured to atomize the aqueous solution and generate a mist group of the aqueous solution in which the gas is diffused; a fluorescence measuring unit configured to measure a fluorescence intensity of the mist group; and an air current generator configured to form an air current flowing toward the fluorescence measuring unit from the atomization unit. | 2013-09-19 |
20130244227 | METHOD FOR AMPLIFICATION-FREE NUCLEIC ACID DETECTION ON OPTOFLUIDIC CHIPS - An optofluidic platform is constructed so as to comprise a planar, liquid-core integrated optical waveguides for specific detection of nucleic acids. Most preferably, the optical waveguides comprises antiresonant reflecting optical waveguide (ARROWs). A liquid solution can be prepared and introduced into the optofluidic platform for optical excitation. The resulting optical signal can be collected at the edges of the optofluidic platform and can be analyzed to determine the existence of a single and/or a specific nucleic acid. | 2013-09-19 |
20130244228 | RAPID TEST FOR THE QUALITATIVE AND/OR QUANTITATIVE ANALYSIS OF ANTIBODIES AGAINST HUMAN PAPILLOMA VIRUSES (HPV) PRESENT IN BODY FLUID, AND DEVICE FOR CARRYING OUT THE RAPID TEST - A rapid test for a qualitative and/or quantitative assay of antibodies present in body fluid against human papilloma viruses (HPV) includes mixing a specimen of body fluid with a reagent which essentially comprises a predetermined quantity of physiologically acting liquid and a predetermined quantity of at least one HPV-specific antigen. The mixture is fed to an analysis which utilizes a change that is at least one of measurable or perceivable by a user. | 2013-09-19 |
20130244229 | BUFFERING COMPOSITIONS ENCLOSED IN A SIZE EXCLUSION MATRIX - The present invention relates to a buffering composition, more closely a composition comprising porous matrix-enclosed buffering agent(s) giving a stabilisation of pH when applied in for example aqueous environment. | 2013-09-19 |
20130244230 | METHODS AND MEANS FOR CHARACTERIZING ANTIBIOTIC RESISTANCE IN MICROORGANISMS - The present invention relates to a method for characterizing the antibiotic resistance of a microorganism, said method comprising the steps of (a) providing a reference mass spectrum of an antimicrobial compound, its enzymatic modification product, its molecular target, or of a substrate compound of a its modifying enzyme; (b) exposing a microorganism, a cell lysate thereof, or a growth medium supernatant thereof, to said antimicrobial compound or said substrate compound in aqueous liquid to thereby provide an exposed sample; (c) acquiring a mass spectrum of the exposed sample; (d) comparing the mass spectrum acquired in step c) with the reference mass spectrum of step (a), and (e) determining from said comparison whether modification of said antimicrobial compound, its modification product or its molecular target or of said substrate has occurred following said exposure, and establishing that said microorganism is potentially resistant to said antimicrobial compound when said modification is observed. | 2013-09-19 |
20130244231 | NOVEL EXPRESSION VECTOR - Disclosed are a novel expression vector for efficient expression of recombinant proteins in mammalian cells, a mammalian cell transformed with the vector, and a method for production of the mammalian cell. The expression vector includes a gene expression regulatory site, and a gene encoding the protein downstream thereof, and an internal ribosome entry site further downstream thereof, and a gene encoding a glutamine synthetase further downstream thereof. | 2013-09-19 |
20130244232 | HIGH-EFFICIENCY CATALYSTS, PREPARATION AND USE THEREOF - Disclosed are new molecules, on a peptide-porphyrin base, with a low molecular weight (2000-5000 uma), optionally in covalent association with biomolecules, which are able to catalyse peroxidation, oxidation, hydroxylation, phenol nitration and inert compound epoxidation reactions, using clean reagents such as H | 2013-09-19 |
20130244233 | Methods and Materials for Determining Pain Sensitivity and Predicting and Treating Related Disorders - Methods of treating somatosensory disorders and modulating production of proinflammatory cytokines by administering to a subject an effective amount of a COMT modulator, ADRB2 modulator, ADRB3 modulator or combinations thereof are provided. Methods of predicting effective pharmacological therapies for a subject afflicted with a somatosensory disorder by determining a genotype of the subject with regard to a gene selected from the group consisting of COMT, ADRB2, ADRB3, and combinations thereof are further provided. Methods of determining pain responses or pain perception and predicting susceptibility of a subject to develop related disorders, such as somatosensory disorders and somatization, by determining a genotype of the subject with regard to a gene selected from the group consisting of COMT, ADRB2, ADRB3, and combinations thereof are further provided. | 2013-09-19 |
20130244234 | STOOL COLLECTION METHODS FOR ANALYSIS OF DNA IN STOOL - Methods of stool sample collection for improving DNA extraction and analysis from stool samples. More specifically, collecting stool samples from the same patient on two or more days (consecutively or randomly) and combining those stool samples for improved DNA extraction and analysis. | 2013-09-19 |
20130244235 | METHODS AND MATERIALS FOR NONINVASIVE DETECTION OF COLORECTAL NEOPLASIA ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE - The present invention provides methods and materials related to the detection of colorectal neoplasia (CRN) associated with inflammatory bowel disease (IBD). The present invention provides markers specific for colorectal neoplasia associated with inflammatory bowel disease in or associated with a subject's stool sample. In particular, the present invention provides methods and materials for identifying mammals (e.g., humans) having colorectal neoplasia associated with inflammatory bowel disease by detecting the presence and level of indicators of colorectal neoplasia such as, for example, epigenetic alterations (e.g., DNA methylation) (e.g., CpG methylation) (e.g., CpG methylation in coding or regulatory regions of BMP3, NDRG4, vimentin, EYA4) in DNA from a stool sample obtained from the mammal. | 2013-09-19 |
20130244236 | PREDICTING RISK OF MAJOR ADVERSE CARDIAC EVENTS - Measurement of circulating ST2 and natriuretic peptide (e.g., NT-proBNP) concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, transplantation, and heart failure. | 2013-09-19 |
20130244237 | Methods and Compositions for Discrimination Between Cytosine and Modifications Thereof and for Methylome Analysis - Compositions and methods are provided for discrimination between cytosine and modifications thereof using cytidine deaminases and/or oxygenases. Variants of wild type cytidine deaminases are described which show reduced bias with respect to adjacent nucleotides upstream of the cytosine. The methods provide a rapid and convenient use of enzymes to obtain methylomes. | 2013-09-19 |
20130244238 | NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES - This invention features systems and methods for the detection of analytes, and their use in the treatment and diagnosis of disease. | 2013-09-19 |
20130244239 | NUCLEIC ACID CONSTRUCT AND COMPLEX FORMATION METHOD AND SCREENING METHOD USING THE SAME - The present invention is to provide a new detection method that is superior in detection sensitivity and allows a simple operation. A nucleic acid construct that includes a cloning region, an encoding nucleic acid of a peptide tag, an encoding nucleic acid of an aptamer that is bindable to the peptide tag is used. By inserting the encoding nucleic acid of arbitrary peptide into the cloning region of the nucleic acid construct, the nucleic acid construct is expressed in vivo. Thereby, a complex of a fusion transcript having the base sequence that includes the encoding nucleic acid of arbitrary peptide, the encoding nucleic acid of a peptide tag, and the encoding nucleic acid of the aptamer and a fusion translation that includes the arbitrary peptide and the peptide tag is formed. By bringing the complex into contact with a target and recovering the complex that is bound to the target, the peptide that is bindable to a target and its encoding nucleic acid can be identified from the transcript of the encoding nucleic acid of arbitrary peptide in the complex. | 2013-09-19 |
20130244240 | SYSTEMS AND METHODS FOR MONITORING THE AMPLIFICATION AND DISSOCIATION BEHAVIOR OF DNA MOLECULES - The present invention relates to systems and methods for monitoring the amplification of DNA molecules and the dissociation behavior of the DNA molecules. | 2013-09-19 |
20130244241 | Test Cartridge With Integrated Transfer Module - A system that includes a cartridge housing and a hollow transfer module, according to an embodiment is described herein. The cartridge housing further includes at least one sample inlet, a plurality of storage chambers, a plurality of reaction chambers, and a fluidic network. The fluidic network is designed to connect the at least one sample inlet, a portion of the plurality of storage chambers and the portion of the plurality of reaction chambers to a first plurality of ports located on an inner surface of the cartridge housing. The hollow transfer module includes a second plurality of ports along an outer surface of the transfer module that lead to a central chamber within the transfer module. The transfer module is designed to move laterally within the cartridge housing. The lateral movement of the transfer module aligns at least a portion of the first plurality of ports with at least a portion of the second plurality of ports. | 2013-09-19 |
20130244242 | METHOD AND SYSTEM FOR ACOUSTICALLY TREATING MATERIAL - Methods and systems for acoustically treating material using a continuous process in which material may be caused to flow in a continuous or intermittent fashion into/out of an acoustic treatment chamber where the material is exposed to focused acoustic energy. The methods and systems may be arranged to permit continuous processing for extended periods while an acoustic energy source operates at a relatively high power output. Treatment chambers may include features such as an acoustic window, a heat exchanger, inlet/outlet flow arrangements, an inspection window, insert elements that define a treatment volume size or shape, etc. Treatment system configurations relating to arrangements of a treatment chamber relative to an acoustic source and coupling medium, material flow paths, and others are provided. | 2013-09-19 |
20130244243 | METHOD FOR PRODUCING EXPRESSION PRODUCT OF EXOGENOUS GENE IN YEAST, REGULATOR OF EXPRESSION IN YEAST, AND USE THEREOF - Provided is a method for producing an expression product of an exogenous gene in a yeast with superior output regulation of gene expression. This is a method for producing an expression product of an exogenous gene in a yeast, including using one or two or more kinds of yeast gene terminator regions selected based on expression intensity data related to the expression intensity of yeast gene terminator regions to cause expression of a gene in a yeast. | 2013-09-19 |
20130244244 | PREDICTING ALLERGIC REACTIONS - This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitroassay employing autologous bloodderived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis. | 2013-09-19 |
20130244245 | Orthogonal Translation Components for the in Vivo Incorporation of Unnatural Amino Acids - The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate unnatural amino acid into proteins produced in eubacterial host cells such as | 2013-09-19 |
20130244246 | IMMORTALIZED AVIAN CELL LINES COMPRISING E1A NUCLEIC ACID SEQUENCES - This invention relates to immortalized avian cells, and to the use of these cells for the production of viruses. The cells according to the invention are particularly useful for the production of recombinant viral vectors which can be used for the preparation of therapeutic and/or prophylactic compositions for the treatment of animals and more particularly humans. | 2013-09-19 |
20130244247 | STRAINS OF SACCHAROMYCES CEREVISIAE - A method for producing a strain of | 2013-09-19 |
20130244248 | METHOD FOR ISOLATING A CHEMOTHERAPEUTIC AGENT RESISTANT CANCER CELL WITH STEM CELL PROPERTIES - The invention relates to the use of encapsulates of cancer cells, in agarose coated, agarose containing beads, for isolating chemotherapeutic resistant cells which have at least one stem cell property, such as expression of OCT4. The cells thus isolated are also a feature of the invention, as is a method for screening for potential therapeutic | 2013-09-19 |
20130244249 | HIERARCHICAL FILMS HAVING ULTRA LOW FOULING AND HIGH RECOGNITION ELEMENT LOADING PROPERTIES - Hierarchical films with structurally regulated functionalities through the integration of two-dimensional and three-dimensional structures to achieve ultra low nonspecific binding and high loading of molecular recognition elements, and methods for making and using the films. | 2013-09-19 |
20130244250 | ANALYTE SENSORS, METHODS FOR PREPARING AND USING SUCH SENSORS, AND METHODS OF DETECTING ANALYTE ACTIVITY - Analyte sensors, methods for producing and using analyte sensors, methods of detecting and/or measuring analyte activity, detecting pH change, and/or, controlling the concentration of an analyte in a system, are disclosed. Embodiments of the analyte sensors according to the disclosure can provide an accurate and convenient method for characterizing analyte activity, detecting pH change, controlling the concentration of an analyte in a system, and the like, in both in vivo and in vitro environments, in particular in living cell imaging. | 2013-09-19 |
20130244251 | BODIPY Structure Fluorescence Dye for Neural Stem Cell Probe - The present invention is directed to a fluorescence compound represented by structural Formula (I), with specificity to neural stem cells: I or a pharmaceutically acceptable salt thereof. The variables for structural Formula (I) are defined herein. Also described are methods for detection of neural stem cells, comprising using a compound of structural Formula (I) or pharmaceutically acceptable salts thereof. Compounds of structural Formula (I) can detect and separate neural stem cells without immunostaining, providing a much shorter and more convenient method for detection of neural stem cells. | 2013-09-19 |
20130244252 | GRAM STAINING METHOD WITH IMPROVED DECOLORIZATION OF THE CRYSTAL VIOLET-IODINE COMPLEX FROM GRAM NEGATIVE BACTERIA - Provided herein are methods of staining biological material for the purpose of detecting, and in some examples also identifying, microorganisms. Methods of Gram staining bacteria using a slow-acting decolorizing formulation, such as one that includes 1,2-propandiol or ethylene glycol, can be used to extend the time of the decolorizing step, and thus permit automation of the Gram staining method. Also provided are compositions and kits for performing automated Gram staining on microscope slides. | 2013-09-19 |
20130244253 | COMPOUNDS HAVING ACTIVITY OF SUPPRESSING ACTIVATION OF TGF-BETA RECEPTOR, METHOD FOR SCREENING OF THE COMPOUNDS, AND COMPOSITION FOR PREVENTING OR TREATING DISEASE CAUSED BY HEPATITIS C VIRUS - An object is to provide a compound capable of inhibiting activation of TGF-β receptors due to HCV, and a screening method for the compound. It has been found that a HCV-derived NS3 protease binds to type I TGF-β receptor, and this binding results in activation of TGF-β receptors. Moreover, binding sites between the NS3 protease and type I TGF-β receptor were identified, and it has been found that antibodies recognizing these binding sites inhibit activation of TGF-β receptors due to NS3 protease. Furthermore, it has been also found that screening for a compound capable of inhibiting activation of TGF-β receptors can be performed by using the inhibition of the binding between NS3 protease and type I TGF-β receptor or the like as an index. | 2013-09-19 |
20130244254 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS - Newly identified mammalian taste-cell-specific G protein-coupled receptors which function as hetero-oligomeric complexes in the sweet taste transduction pathway, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in sweet taste signaling as hetero-oligomeric complexes, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for identifying putative taste modulating compounds using such hetero-oligomeric complexes also described, as is a novel surface expression facilitating peptide useful for targeting integral plasma membrane proteins to the surface of a cell. | 2013-09-19 |
20130244255 | ANTIBODIES DIRECTED TO GPNMB AND USES THEREOF - The present invention relates to antibodies with specificity to GPNMB, and uses of such antibodies. In particular, the present invention provides fully human monoclonal antibodies that specifically bind to GPNMB, and uses thereof. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs) are provided. The present invention also provides biomarkers for evaluating the effects of therapeutic methods and uses of the antibodies with specificity to GPNMB. | 2013-09-19 |
20130244256 | Compositions and Methods for Treating and Diagnosing Cancer - The present invention relates to compositions and methods for treating, characterizing, and diagnosing cancer. In particular, the present invention provides gene expression profiles associated with solid tumor stem cells, as well as novel stem cell cancer markers useful for the diagnosis, characterization, and treatment of solid tumor stem cells. | 2013-09-19 |
20130244257 | INTEGRATED MICROFLUIDIC RADIOASSAY AND IMAGING PLATFORM FOR SMALL SAMPLE ANALYSIS - An immunocapture-based in vitro kinase assay on an integrated polydimethylsiloxane (PDMS) microfluidics platform that can reproducibly measure kinase activity from as few as 3,000 cells is described. For this platform, the standard radiometric | 2013-09-19 |
20130244258 | Sensitive and Specific Assay for Babesia spp. - The invention is directed to methods of using novel | 2013-09-19 |
20130244259 | NOVEL TESTING METHOD AND TESTING REAGENT FOR ANGIITIS - [Problem] The present invention provides a novel pathological marker of angiitis which serves as an alternative to MPO-ANCAs. | 2013-09-19 |
20130244260 | METHOD FOR DISCRIMINATING BETWEEN EARLY AND ADVANCED STAGE LUNG CARCINOMA - The present invention relates to a method for discriminating between early and advanced stage lung carcinoma in an individual suffering from lung carcinoma comprising the steps of a) providing a sample of an individual suffering from lung carcinoma, b) determining the level of heat shock protein 27 (HSP27) in said sample, c) comparing the determined level of HSP27 in said sample with a reference range of HSP27 measured in samples of control individuals with an early stage lung carcinoma and/or with advanced stage lung carcinoma, d) diagnosing early stage lung carcinoma in said individual when the level of HSP27 in sample a) is below the reference range of HSP27 in samples of control individuals with advanced stage lung carcinoma or within the reference range of control individuals with early stage lung carcinoma and diagnosing advanced stage lung carcinoma when the level of HSP27 in sample a) is above the reference range of HSP27 in samples of control individuals with early stage lung carcinoma or within the reference range of control individuals with advanced stage lung carcinoma. | 2013-09-19 |
20130244262 | CARDIOMYOCYTE- AND/OR CARDIAC PROGENITOR CELL-PROLIFERATING AGENT AND METHOD FOR PROLIFERATING CARDIOMYOCYTES AND/OR CARDIAC PROGENITOR CELLS - The present invention provides a cardiomyocyte- and/or cardiac progenitor cell-proliferating agent comprising at least one compound selected from the group consisting of: a GSK3β inhibitor, ERK dephosphorylation inhibitor, Raf activator, CaMK2 inhibitor and p38 inhibitor; and a method for proliferating cardiomyocytes and/or cardiac progenitor cells using the agent. | 2013-09-19 |
20130244263 | METHOD OF IDENTIFYING WHEN A PATIENT UNDERGOING HEMODIALYSIS IS AT INCREASED RISK OF DEATH - The invention is directed to a method of identifying a patient undergoing periodic hemodialysis treatments at increased risk for death that includes determining at least one of the patient's clinical or biochemical parameters, consisting of serum bicarbonate concentration level, serum potassium concentration level, serum calcium concentration level, hemoglobin concentration level, serum phosphorus concentration level, neutrophil to lymphocyte ratio, equilibrated normalized protein catabolic rate (enPCR), equilibrated fractional clearance of total body water by dialysis and residual kidney function (eKdrt/V), EPO resistance index, transferrin saturation index, serum ferritin concentration level, serum creatinine concentration level, platelet count, Aspartat-Aminotransferase level, and Alanin-Aminotransferase level at periodic hemodialysis treatments, and identifying a patient as having an increased risk for death if the patient has a significant change in the rate of change of at least one of the patient's clinical or biochemical parameters. The invention is also directed to a method of identifying an increased mortality risk factor for a patient undergoing periodic hemodialysis treatment. The method includes analyzing data of deceased patients that were previously undergoing periodic hemodialysis treatments by performing a longitudinal analysis backwards in time of changes in a clinical or biochemical parameter the patients, and identifying a significant change in the rate of decline or the rate of increase in a clinical or biochemical parameter before death of the patients. | 2013-09-19 |
20130244264 | Measurement Method Using Enzyme - A method for measuring an analyte is described that includes the steps of: i) preparing a reagent (D) in which an enzyme (A) and an enzyme (B) coexist in the absence of the analyte; ii) bringing the analyte into contact with the enzyme (A) and the enzyme (B) so that the enzyme (A) acts on the analyte to produce a product (E), on which the enzyme (B) does not substantially act, from the analyte; iii) producing a product (C) by allowing the enzyme (A) or an enzyme (F) that is different from the enzyme (A) that acts on the analyte to produce a product (C) to act on the analyte and/or the product (E); and iv) detecting the product (C) by the enzyme (B). | 2013-09-19 |
20130244265 | SECRETION OF RECOMBINANT POLYPEPTIDES IN THE EXTRACELLULAR MEDIUM OF DIATOMS - A transformed diatom includes a nucleic acid sequence operatively linked to a promoter, wherein the nucleic acid sequence encodes an amino acid sequence including (i) an heterologous signal peptide and (ii) a polypeptide, the heterologous signal peptide leading to the secretion of the polypeptide in the extracellular medium of the transformed diatom; a method for producing a polypeptide which is secreted in the extracellular medium, the method including the steps of (i) culturing a transformed diatom, (ii) harvesting the extracellular medium of the culture and (iii) purifying the secreted polypeptide in the extracellular medium; and use of the transformed diatom for the secretion of a polypeptide in the extracellular medium. | 2013-09-19 |
20130244266 | BIOSENSING SYSTEMS FOR MEASUREMENT OF LACTOSE - Herein disclosed are biosensing systems that measure lactose concentration in a solution. | 2013-09-19 |
20130244267 | COMPOSITIONS AND METHODS FOR QUADRICYCLANE MODIFICATION OF BIOMOLECULES - The present disclosure features a strain-promoted [2+2+2] reaction that can be carried out under physiological conditions. In general, the reaction involves reacting a pi-electrophile with a low lying LUMO with a quadricyclane on a biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo and in vitro. The reaction is compatible with modification of living cells. In certain embodiments, the pi-electrophile can comprise a molecule of interest that is desired for delivery to a quadricyclane-containing biomolecule via [2+2+2] reaction. | 2013-09-19 |
20130244268 | CANCER STEM CELLS EXPRESSING ABCG2 - Cancer Stem Cell populations characterized by expression of ABCG2 and methods of isolating and using the same are disclosed. | 2013-09-19 |
20130244269 | MEASURING LEVELS OF A METABOLITE - Described herein are methods for determining an amount of an analyte in a test sample. The methods involve preparing a calibration curve using standard samples containing an isotopically-labeled standard in a biological matrix. | 2013-09-19 |
20130244270 | MICROFLUIDIC DEVICE FOR CELL MOTILITY SCREENING AND CHEMOTAXIS TESTING - The present invention relates to a microfluidic device used for cell motility screening and chemotaxis testing which comprises microfluidic channels and chambers. Cells which can secret a chemoattractant or chemorepellent are selectively planted in the microfluidic device and a stable chemoattractant or chemorepellent gradient can be established in the channels. | 2013-09-19 |
20130244271 | METHOD AND DEVICE FOR MONITORING A CRYOPRESERVED BIOLOGICAL SAMPLE - The invention relates to a method for monitoring a cryopreserved biological sample ( | 2013-09-19 |
20130244272 | PROCESS FOR DETERMINING MYCOTOXIN PRODUCTION FROM A SPECIFIC CHEMICAL FINGERPRINT - The present invention relates to a process for determining mycotoxin production in an interior environment which includes a search for a chemical fingerprint comprising at least one target molecule that is a VOC, optionally cyclic, associated with mycotoxin production, preferably selected from the group comprising cububene, cadiene, copaene, ylangene, D germacrene, muurolane, 1,1-dimethylbutylbenzene, 1,1,2-trimethyl-propyl-benzene, 1-hexyltetradecylbenzene, tetratetracontane, 1-ethyldecylbenzene, hydroxytoluene butylate, 1-butyloctylbenzene, 1-propylnonylbenzene, 2-methylisoborneol and at least one sesquiterpene. | 2013-09-19 |
20130244273 | Determination of Decreased Metabolism of Tryptophan in Diagnosis of Autism Spectrum Disorders - Methods for diagnosis of autism spectrum disorders are described. Methods include culturing a cell sample of a test subject with a tryptophan-containing energy source and examining the culture to determine the ability of the cells of the test subject to properly metabolize tryptophan. A determination that a subject does not properly metabolize tryptophan is an indication that the subject may be afflicted with autism. Methods can be utilized as a quick and reliable diagnostic tool for autism spectrum disorders and may provide a unifying model for the genetic heterogeneity of autism spectrum disorders. | 2013-09-19 |
20130244274 | SAMPLE PROCESSING APPARATUS AND REAGENT INFORMATION INFORMING METHOD - A sample processing apparatus comprises a sample processing unit that carries out processing of a sample using a reagent, an acquiring device that acquires reagent information regarding a reagent in a reagent container provided to the reagent container, an audio output unit that outputs audio, and a control device that manages the reagent information of the reagent in a state of being used by the sample processing unit. The audio output unit outputs audio guidance regarding the acquired reagent information when the acquiring device acquires new reagent information regarding a reagent not in a state of being used by the sample processing unit. | 2013-09-19 |
20130244275 | METHOD FOR OPTIMIZING A BIOPHARMACEUTICAL PRODUCTION PROCESS - The invention describes the development of a new buffer system for cell culture media for establishing a CO | 2013-09-19 |
20130244276 | Production of proteins in filamentous fungi - The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to be deficient or to overexpress specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host. | 2013-09-19 |
20130244277 | Gene Expression Technique - The present invention provides a host cell suitable for enhanced production of a protein product of choice characterised in that the host cell is genetically modified to cause over-expression of two or more helper proteins selected from a DnaJ-like protein (such as JEM1), an Hsp70 family protein (such as LHS1) and SIL1, wherein at least one of the over-expressed two or more helper proteins is selected from JEM1, LHS1 and SIL1, and wherein the DnaJ-like protein is not SCJ1. | 2013-09-19 |
20130244278 | FORMULATION AND DELIVERY OF PLGA MICROSPHERES - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 2013-09-19 |
20130244279 | FORMULATION AND DELIVERY OF PLGA MICROSPHERES - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 2013-09-19 |
20130244280 | EXPRESSION VECTOR FOR HIGH LEVEL EXPRESSION OF RECOMBINANT PROTEINS - The present invention provides an expression vector for the production of proteins and peptides comprising a promoter operably linked to gene of interest, TPL and VA genes I and II, matrix attachment regions (MARs)/SARs, and antibiotic marker. The vector is transfected in suitable host cell. | 2013-09-19 |
20130244281 | Toll-Like Receptor 3 Antagonists - Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 2013-09-19 |
20130244282 | METHOD OF PRODUCING ANTIBODIES - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins. | 2013-09-19 |
20130244283 | Process for Protein Production - The present invention relates to a process for the production of a haemostasis protein by continuous perfusion culturing of a cell culture in suspension, said cell culture expressing said haemostasis protein into said culture suspension, wherein the cell culture flows across a filter module, which filter module leads to a harvest port, the filter module having a mesh size of from 0.1 to 2.9 μm allowing passage across of the haemostasis protein and wherein the flow across the filter module is an alternating tangential flow. The invention also relates to a protein produced by the process of the invention. | 2013-09-19 |
20130244284 | METHOD FOR SUBJECTING SOLID BIOMASS TO SACCHARIFICATION PRETREATMENT, APPARATUS THEREFOR, AND METHOD FOR SACCHARIFICATION OF SOLID BIOMASS - Solid biomass having a moisture content in a range of 30 to 95 mass % is brought into contact with ammonia gas at a pressure in a range of 0.5 to 4 MPa and held at 50 to 200 degrees C. Subsequently, the solid biomass is rapidly decompressed to be blasted. The ammonia gas evaporated by decompression is recovered and recycled. The ammonia gas can be brought into contact with the entire solid biomass evenly and in a short time. Since absorption heat of the ammonia gas is generated, energy consumption required for additional heating can be reduced. | 2013-09-19 |
20130244285 | METHOD AND SYSTEM FOR ACOUSTICALLY TREATING MATERIAL - Methods and systems for acoustically treating material using a continuous process in which material may be caused to flow in a continuous or intermittent fashion into/out of an acoustic treatment chamber where the material is exposed to focused acoustic energy. The methods and systems may be arranged to permit continuous processing for extended periods while an acoustic energy source operates at a relatively high power output. Treatment chambers may include features such as an acoustic window, a heat exchanger, inlet/outlet flow arrangements, an inspection window, insert elements that define a treatment volume size or shape, etc. Treatment system configurations relating to arrangements of a treatment chamber relative to an acoustic source and coupling medium, material flow paths, and others are provided. | 2013-09-19 |
20130244286 | COMPOSITIONS AND METHODS FOR cDNA SYNTHESIS - Methods for making cDNA molecules, for amplification of RNA by PCR and for preparation of cDNA libraries are provided. Kits for making cDNA molecules also are provided. | 2013-09-19 |