37th week of 2008 patent applcation highlights part 52 |
Patent application number | Title | Published |
20080221307 | Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto - The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and the antigen binding proteins, such as antibodies, that bind thereto and inhibit IL-17 ligand family members from binding to and activating IL-17 Receptor A or a receptor complex comprising IL-17 Receptor A. | 2008-09-11 |
20080221308 | HDAC9 polypeptides and polynucleotides and uses thereof - The present invention features substantially pure HDAC9, HDAC9a, HDAC9(ΔNLS), HDAC9a(ΔNLS), an HDRP(ΔNLS) polypeptides, and isolated nucleic acid molecules encoding those polypeptides. The present invention also features vectors containing HDAC9, HDAC9a, HDAC9(ΔNLS), HDAC9a(ΔNLS), and HDRP(ΔNLS) nucleic acid sequences, and cells containing those vectors. | 2008-09-11 |
20080221309 | MN Gene and Protein - A new gene—MN—and proteins/polypeptides encoded therefrom are disclosed. Recombinant nucleic acid molecules for expressing MN proteins/polypeptides and recombinant proteins are provided. Expression of the MN gene is disclosed as being associated with tumorigenicity, and the invention concerns methods and compositions for detecting and/or quantitating MN antigen and/or MN-specific antibodies in vertebrate samples that are diagnostic/prognostic for neoplastic and pre-neoplastic disease. Test kits embodying the immunoassays of this invention are provided. MN-specific antibodies are disclosed that can be used diagnostically/prognostically, therapeutically, for imaging, and/or for affinity purification of MN proteins/polypeptides. Also provided are nucleic acid probes for the MN gene as well as test kits comprising said probes. The invention also concerns vaccines comprising MN proteins/polypeptides which are effective to immunize a vertebrate against neoplastic diseases associated with the expression of MN proteins. The invention still further concerns antisense nucleic acid sequences that can be used to inhibit MN gene expression, and polymerase chain reaction (PCR) assays to detect genetic rearrangements. | 2008-09-11 |
20080221310 | Extraction of Cellular Components with Fatty Acid Derivatives - A method of treating biologic material with a composition containing at least one fatty acid derivative and/or at least one fatty alcohol, a buffer, and a salt to result in protein partitioning into an aqueous phase and an organic phase. The protein may be a membrane protein. The cells may be plant cells and/or animal cells. The proteins can be thereafter be used for downstream applications. | 2008-09-11 |
20080221311 | Preparation method of insect cell extract solution for cell-free protein synthesis, the insect cell extract solution and cell-free synthesis method of protein using the insect cell extract solution - The present invention provides a preparation method of an insect cell extract solution for cell-free protein synthesis, the insect cell extract solution, a protein synthesis method in a cell-free system, which uses the insect cell extract solution, and a kit for cell-free protein synthesis containing the insect cell extract solution. The extract solution is easily prepared by the method of the present invention and can synthesize a higher amount of protein than by extract solutions prepared by conventional methods. | 2008-09-11 |
20080221312 | METHOD FOR CRYSTALLIZING SUCRALOSE - The present application discloses a method for crystallizing sucralose, which uses an alcohol solvent or a mixed solvent of alcohol and other solvent(s) in the crystallization of sucralose. | 2008-09-11 |
20080221313 | PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE DEACYLATION OF TRICHLOROSUCROSE-6-ETHYL ESTER - The present invention discloses a process for the preparation of sucralose by the deacylation of trichlorosucrose-6-ethyl ester, wherein the deacylation reaction is performed in an alcohol solvent in the presence of organic base catalyst, so as to obtain sucralose. | 2008-09-11 |
20080221314 | Heteromolecular metal-humic (chelate) complexes - Heteromolecular metal-humic organic complexes of the type: | 2008-09-11 |
20080221315 | NUCLEIC ACID-BASED TRANSLATION SYSTEM AND METHOD FOR DECODING NUCLEIC ACID ENCRYPTED MESSAGE - A nucleic acid-based translation system where the components of a nucleic acid multicrossover molecule serve as message, translation device and part of the translated product. One continuous strand of a nucleic acid multicrossover molecule acts as a message, which nucleic acid crossover strands, functioning together as a translation device, translate into nucleic acid product strands. Organic molecules appended to the backbone of the nucleic acid product strands can also be polymerized to form a polymer sequence of appended organic molecules. | 2008-09-11 |
20080221316 | siRNA targeting ethanolamine Kinase I1 (EKI1) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to EKI1. | 2008-09-11 |
20080221317 | siRNA targeting cystic fibrosis transmembrane conductance regulator (CFTR) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to CFTR. | 2008-09-11 |
20080221318 | Cellulose- or Lignocellulose-Containing Composite Materials Based on a Silane-Based Composite as a Binder - The present invention relates to a composite material based on (a) a cellulose- or lignocellulose-containing material and (b) a composite as a binder, the composite resulting from the reaction of at least the components (i) a glycidyloxypropylalkoxysilane, (ii) an aqueous silica sol having a solids content of >20% by weight, (iii) an organic acid as a hydrolysis catalyst and (iv) n-propyl zirconate, butyl titanate or titanium acetylacetonate as a crosslinking agent. The present invention furthermore relates to a process for the production of said composite materials and the use of a composite (b) as a binder for the production of wood-based materials. | 2008-09-11 |
20080221319 | METHOD OF MAKING PORPHYRINS - A method of making a compound of Formula I: | 2008-09-11 |
20080221320 | Process For The Preparation Of 10,11-Dihydro-10-Hydroxy-5H-Dibenz[B,F]Azepine-5-Carboxyamide - A process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxyamide by hydrolysis of 5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine with peroxy compounds in alkali medium and in the presence of solvents. | 2008-09-11 |
20080221321 | Preparing Salts of Dihydroxychlorotriazine - The present invention is directed to a process for preparing salts of dihydroxychlorotriazine. The process comprises the hydrolysis of cyanuric chloride in alkaline aqueous solution and subsequent crystallization of monosalt of dihydroxychlorotriazine at neutral pH. The crystallization is improved with so-called dispersing assistants. | 2008-09-11 |
20080221322 | CHEMICAL PROCESS - The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline. | 2008-09-11 |
20080221323 | Production of Rosuvastatin Calcium Salt - An improved process for the manufacture of (E)-7-[4-(4-flurophenyl)-6-isopropyl-2-[methyl(methylsulfony)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, Formula (1), which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described. | 2008-09-11 |
20080221324 | Novel Processes For The Preparation Of A 2H-Chromene - The present invention relates to novel processes for the preparation of the compound of formula I (Iclaprim), related to dihydrofolate reductase inhibitors | 2008-09-11 |
20080221325 | Exchange membrane containing modified maleimide oligomers - An exchange membrane containing modified maleimide oligomers comprising sulfonated poly(aryl ether ketone) (S-PAEK) and modified maleimide oligomers. The exchange membrane uses the modified maleimide oligomers having a hyper-branched architecture as matrix, and introduces them into S-PAEK to constitute semi-interpenetration network (semi-IPN), so as to intensify water holding capacity, chemical resistance, the electrochemical stability and thermal resistance of the ionic/proton exchange membrane. The exchange membrane can be used to fabricate the membrane electrode assemblies, fuel cells, and be applied them to the fields of seawater desalination, heavy water and sewage treatment, and biomass-energy resources. | 2008-09-11 |
20080221326 | Shaped Body Containing a Microporous Material and at Least One Silicon-Containing Binder, Method For the Production Thereof and Its Use as a Catalyst, Particularly in a Method For Producing Triethylenediamine (Teda) - Process for producing a shaped body comprising a microporous material and at least one silicon-containing binder, which comprises the steps
| 2008-09-11 |
20080221327 | SYNTHESIS OF GLYT-1 INHIBITORS - The present invention relates to a process for preparation of a compound of formula I | 2008-09-11 |
20080221328 | LUMINESCENT LANTHANIDE COMPLEXES - Neutral lanthanide(III) complexes including at least one ligand are disclosed. The ligand includes a heterocyclic aromatic ring with at least one carboxylic acid group attached thereto, wherein a heteroatom of the heterocyclic ring and the carboxylate function of the carboxylic acid group co-ordinate (chelate) to the lanthanide. The complexes can be used in luminescent lamps and luminescent displays. The complexes can be synthesized by heating a mixture of a lanthanide 3+ salt and ligand L in a suitable solvent until a precipitate of the lanthanide complex forms. In one embodiment, the formal 3+ charge on the lanthanide is neutralized by providing in the ligands for the complex, three coordinating carboxylate groups, (RCO | 2008-09-11 |
20080221329 | Novel and economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer - The present invention relates to a novel and economical process for preparing (S,S)-2, 8-diazabicyclo[4.3.0]nonane, a valuable intermediate used for constructing quinolone and naphthyridine derivatives having antibacterial effectiveness, e.g. moxifloxacin and its enantiomer. | 2008-09-11 |
20080221330 | Mutilin-Derivative Substituted at Position 12 - A position 12-substituted mutilin derivative, a novel mutilin analogue, is provided that exhibits strong antimicrobial activity against abroad spectrum of Gram-positive or Gram-negative bacteria, including various drug-resistant bacteria, as well as intermediates for the production of such mutilin derivatives. | 2008-09-11 |
20080221331 | ALCOHOL OXIDATION CATALYST AND ITS PREPARATION PROCESS - An alcohol oxidation catalyst which is an organic oxidation catalyst to oxidize an alcohol, which contains azabicyclo [3.3.1]nonane N-oxyl represented by the following formula (1) having an N-oxyl group incorporated in a bicycle[3.3.1]nonane skeleton: | 2008-09-11 |
20080221332 | Hindered Amine salt compounds - The present invention relates water-soluble hindered amine compounds of the general formula (I): | 2008-09-11 |
20080221333 | Process for Preparing Beta-Ketoester Compounds - The present invention relates to a process for preparing a beta-keto ester compound of formula (1), which is an intermediate for the synthesis of quinolone antibiotics. Particularly, the present invention is characterized by the reaction of an organo nitrile compound with a salt of mono-alkyl malonate in the presence of metal salt, and so the reaction is easy to control due to its endothermic nature, and is devoid of lachrymatory reagents with excellent reproducibility. Subsequent in situ hydrolysis in the presence of aqueous acid solution provided the compound of formula (1). | 2008-09-11 |
20080221334 | Process for the Preparation of Onium Alkylsulfonates - The invention relates to a process for the preparation of onium alkylsulfonates by reaction of an onium halide or carboxylate with a symmetrically substituted dialkyl sulfite or with an asymmetrically substituted dialkyl sulfite at temperatures of 50 to 170° C. | 2008-09-11 |
20080221335 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method - The invention relates to a method for the manufacture of substituted phosphanes and substituted phosphanes manufactured according to the method. Phosphanes, phosphane oxides, sulfides or selenides are used as ligands in coordination compounds. They play a central role in controlling the activity and selectivity of catalysts. The object is achieved by the invention by synthesizing heterocyclic substituents on aromatic groups by introducing acetyl groups. In this manner, previously unknown representatives of the families of phosphanes, phosphane oxides, sulfides and selenides are made accessible. | 2008-09-11 |
20080221336 | Pparalpha/Gamma Agonists and Processes of Preparing - This invention provides a method for preparing compounds having the structure [Formula (I)] wherein L is [Formula (A)] or [Formula (B)] in which R | 2008-09-11 |
20080221337 | Process for Producing an Aromatic Unsaturated Compound - The present invention provides a process for producing an aromatic unsaturated compound of the formula (4) | 2008-09-11 |
20080221338 | Processes for preparing darifenacin hydrobromide - The invention encompasses processes for the preparation of darifenacin hydrobromide. | 2008-09-11 |
20080221339 | CONVERSION OF CBD TO DELTA8-THC AND DELTA9-THC - Methods of converting cannabidiol to Δ | 2008-09-11 |
20080221340 | Process for the Production of Nebivolol - The subject of the invention is a process for the production of the racemic active ingredient nebivolol, in which diastereomeric cyanohydrins are produced, separated, and the separated diastereomers are coupled to one another after a transformation, preferably a partial or complete reduction of the cyano group or a Pinner saponification. | 2008-09-11 |
20080221341 | Trisoxetane compound, process for producing the same, and opitcal waveguide using the same - The present invention relates to a trisoxetane compound represented by the following formula (1): | 2008-09-11 |
20080221342 | Process - A process for the preparation of aromatic N-glycidylamines is described, wherein an amine which contains at least one aromatic aminehydrogen atom is heated with at least 0.7 equivalent of epichlorohydrin per aminehydrogen equivalent of the aromatic amine, using a divalent or polyvalent metal salt of nitric acid, as a catalyst, dissolved in propylene carbonate, and the product is then dehydrochiorinated. | 2008-09-11 |
20080221343 | Novel hydrazone-based and oxime-based fluorescent and chromophoric/pro-fluorescent and pro-chromophoric reagents and linkers - Conjugationally extended hydrazine compositions of the formula (RR | 2008-09-11 |
20080221344 | Biodiesel fuel and method of manufacture therefor - A method for producing biofuel by a transesterification reaction of an alcohol and a triglyceride such as an oil or fat is carried out at supercritical conditions in a reactor using a stoichiometric excess of alcohol. The reaction products of biofuel and gaseous mixture of glycerine and alcohol are re-cycled through a series of pre-heaters to sequentially raise the temperature and pressure of the reaction mixture prior to delivery to the reactor. Any excess alcohol after separating and recovering gaseous glycerin therefrom is recycled and mixed with “fresh” alcohol. Preferably, the process is a non-catalytic continuous process. | 2008-09-11 |
20080221345 | Use of a Phosphorus Containing Ligand and a Cyclic Organic Ligand in a Transition Metal Compound - According to the present invention there is provided a compound in the form of a transition metal compound including a transition metal, a phosphorus containing ligand, and a cyclic organic ligand. The phosphorus containing ligand is a heterocyclic organic compound with a ligating phosphorus atom which ligates with the transition metal, and which ligating phosphorus atom is an atom in the heterocyclic ring structure of the heterocyclic organic compound. The cyclic organic ligand is a cyclic organic compound with a ligating carbon atom in the cyclic ring structure of the cyclic organic compound which ligates with the transition metal by means of a double bound. The invention also relates to a method preparing such a compound and a metathesis reaction wherein such a compound is used as a catalyst. | 2008-09-11 |
20080221346 | Oriented-film formation apparatus and oriented film - An oriented-film formation apparatus forms an oriented film on a substrate by obliquely evaporating a predetermined material in a vacuum state and includes an evaporation source having an organic-inorganic hybrid material. | 2008-09-11 |
20080221347 | Nucleophile Leaving Groups - Sulfonate leaving groups include a cation chelating moiety, e.g. a polyether or crown ether. The chelating moiety stabilizes the sulfonate leaving group by forming a complex with a cation of a cation-nucleophile combination. The stabilized leaving group is more easily displaced under many conditions than are standard arylsulfonate leaving groups such as the toxyl group. The chelating moiety also favors certain cations depending on the identity of the moiety thereby enhancing the reaction rate with nucleophilic salts containing the preferred cation. Use of the inventive leaving groups results in improved yields, decreased reaction times and improved product purity. | 2008-09-11 |
20080221348 | Industrial Process for Production of Aromatic Carbonate - It is an object of the present invention to provide a specific process that enables an aromatic carbonate to be produced with high selectivity and high productivity stably for a prolonged period of time on an industrial scale of no less than 1 ton per hour using a continuous multi-stage distillation column from a dialkyl carbonate and an aromatic monohydroxy compound containing specified amounts of an alcohol and an aromatic carbonate. Although there have been many proposals regarding the process of producing the aromatic carbonate using a reactive distillation method, these have all been on a small scale and a short operating time laboratory level. There have also been no disclosures whatsoever of a starting material containing necessary amounts of the alcohol and the aromatic carbonate for use in an industrial production, which have been considered to be disadvantageous in terms of the equilibrium, let alone the process and apparatus for the industrial production. According to the present invention, there is provided a specified continuous multi-stage distillation column, and there is also provided a specific process that enables the aromatic carbonate to be produced with high selectivity and high productivity stably for a prolonged period of time on an industrial scale of not less than 1 ton per hour from the dialkyl carbonate and the aromatic monohydroxy compound containing the alcohol and the aromatic carbonate. | 2008-09-11 |
20080221349 | Preparation of Amides of Retinoic Acid Via Mixed Anhydride and Mixed Carbonate Intermediates - Processes for preparing amides of retinoic acid are disclosed. Intermediates useful in the preparation of amides of retinoic acid are also disclosed. In one version of the invention, fenretinide is produced via activation of retinoic acid (tretinoin) via its corresponding mixed anhydride or mixed carbonate followed by reaction of the activated intermediate with 4-aminophenol. Other amides of retinoic acid and isomers of retinoic acid, such as the 9-cis-form or 13-cis-form can also be made by this invention. | 2008-09-11 |
20080221350 | Process for Preparing 2-Arylcarbonyl Compounds, 2-Aryl Esters and 2-Arylnitriles and their Heteroaromatic Analogues - Process for preparing compounds by cross-coupling of enolizable carbonyl compounds, nitriles or their analogues with substituted aryl or heteroaryl compounds in the presence of a Brönsted base and of a catalyst or precatalyst containing a.) a transition metal, a complex, a salt or a compound of this transition metal from the group V, Mn, Fe, Co, Ni, Rh, Pd, Ir, Pt) and b.) at least one sulphonated phosphane ligand in a solvent or solvent mixture. | 2008-09-11 |
20080221351 | Method for the Production of Adipodinitrile by Hydrocyanation of 1,3-Butadiene - A process is described for preparing adiponitrile by hydrocyanating 1,3-butadiene over a catalyst, by, in a first process step, hydrocyanating 1,3-butadiene to 3-pentenenitrile over at least one nickel(0) catalyst, and, in a second process step, hydrocyanating 3-pentenenitrile to adiponitrile over at least one nickel(0) catalyst with addition of at least one Lewis acid, wherein at least one of the at least one nickel(0) catalysts used in the particular process steps is transferred into the other process step. | 2008-09-11 |
20080221352 | Integrated process for producing carbonylation acetic acid, acetic anhydride, or coproduction of each from a methyl acetate by-product stream - The present invention is directed to using methyl acetate from a vinyl acetate-based or a vinyl- or ethylene-alcohol based polymer or copolymer process directly for use in a methanol carbonylation production process to produce acetic acid, acetic anhydride, or a coproduction of each. | 2008-09-11 |
20080221353 | Novel phosphonium salt ionic liquid and reaction solvent including the same - The present invention provides an ionic liquid including a quaternary phosphonium salt represented by general formula (1): | 2008-09-11 |
20080221354 | Process for the Preparation of the Alkoxyamine 2-Methyl-2-[N-(Diethoxyphosphoryl-2,2-Dimethylpropyl)-Aminoxy] Propionic Acid - The present invention relates to a process for the preparation of the alkoxyamine 2-methyl-2-[N-(diethoxy-phosphoryl-2,2-dimethylpropyl)aminoxy]propionic acid or of its salts comprising a stage of saponification of an azo compound in the presence of a base, a stage of photolysis of the salt resulting from the saponification stage in the presence of N-(tert-butyl)-1-diethylphosphono-2,2-dimethylpropyl nitroxide and optionally a stage of acidification of the salt of the alkoxyamine obtained on conclusion of the photolysis stage. | 2008-09-11 |
20080221355 | Method of producing near-infrared absorbing dye compound - A method of producing a near-infrared absorbing dye compound, useful for image forming materials, infrared heat-sensitive recording devices, optical film materials, and the like, containing a process of reacting a compound represented by formula (I) with peroxomonosulfuric acid or its salt. | 2008-09-11 |
20080221356 | Processes for the synthesis of O-desmethylvenlafaxine - The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine. | 2008-09-11 |
20080221357 | Method for Producing Amines from Hydroxamic Acids - A method for producing unprotected or carbamate-protected amines of formulae (II) and (III) or R | 2008-09-11 |
20080221358 | Method of Synthesizing Key Intermediates for the Production of Camptothecin Derivatives - The present invention discloses a process for efficient production of 2-amino-5-hydroxypropiophenone corresponding to the AB ring part of camptothecin (CPT) skeleton, which is a key intermediate useful for the total synthesis of camptothecin analogs including 7-Ethyl-10-hydroxy camptothecin and novel intermediates thereof. | 2008-09-11 |
20080221359 | Method for Producing Ethylene Amines - Processes comprising: providing a starting material comprising ethylenediamine; and reacting the starting material in the presence of a heterogeneous transition metal catalyst to form one or more ethylene amines; wherein the catalyst comprises a catalytically active composition, which prior to treatment with hydrogen, comprises a mixture of oxygen-containing compounds of aluminum, copper, nickel and cobalt; and wherein the catalyst is present as one or more shaped catalyst particles selected from spheres, extrudates, pellets and other geometries, wherein the sphere or extrudate has a diameter of <3 mm, the pellet has a height of <3 mm, and the other geometries have an equivalent diameter L=1/a′ of <0.70 mm, where a′ is the external surface area per unit volume (mm | 2008-09-11 |
20080221360 | Alkylamino Group-Treminated Fluoroether and Process for Producing the Same - An alkylamino group-terminated fluoroether compound, represented by the following general formula: | 2008-09-11 |
20080221361 | Ionic Liquids - The invention provides ionic liquids and processes for their preparation. The liquids may either comprise a cation of the formula (I); N | 2008-09-11 |
20080221362 | Optically-active bis(alkynylphosphino) ethane-borane derivative and process for producing the same - An optically-active bis(alkynylphosphino)ethane-borane derivative represented by formula (1): | 2008-09-11 |
20080221363 | Process for the Monosulfonation of Aromatic Phosphines, and Zwitterionic Product Derived Therefrom - A method of preparing an aromatic phosphine monosulfonate in zwitterionic form, such as dicyclohexylphenylphosphine monosulfonate zwitterion, involving contacting an aromatic phosphine with a sulfonating agent to provide a reaction mixture containing aromatic phosphine monosulfonate in acid form and unconverted sulfonating agent; quenching or removing substantially all of the unconverted sulfonating agent; partially neutralizing the aromatic phosphine monosulfonate in acid form to phase separate aromatic phosphine monosulfonate in zwitterionic form as a solid or neat liquid layer; and collecting the zwitterion as a solid or neat liquid. The zwitterion may be neutralized to form the corresponding aromatic phosphine monosulfonate metal salt, which is useful in preparing catalysts for hydroformylation processes. | 2008-09-11 |
20080221364 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS - Novel substituted phenylsulfur trifluorides that act as fluorinating agents are disclosed. Also disclosed are methods for their preparation and methods for their use in introducing one or more fluorine atoms into target substrate compounds. Finally, various intermediate compounds for use in preparing substituted phenylsulfur trifluorides are provided. | 2008-09-11 |
20080221365 | PROCESS FOR STABILIZING CYCLOBUTANONE DERIVATIVES - A process for stabilizing cyclobutanone derivatives, comprising adding at least one of an alkali metal carbonate, alkali metal oxide, alkaline earth metal carbonate, and alkaline earth metal oxide as a stabilizer to at least one cyclobutanone derivative of the structure | 2008-09-11 |
20080221366 | Method for the Hydrogenation of Mass Fluxes Containing Aldehyde - The present application relates to a process for reacting a composition I comprising at least one aldehyde with hydrogen in the presence of a catalyst in at least one main reactor and at least one postreactor, wherein at least 50% of the fresh hydrogen fed to the reaction system is fed into at least one postreactor. In a preferred embodiment, composition I comprises at least one further organic compound. | 2008-09-11 |
20080221367 | Horizontal Reactor Vessel - Horizontal reactor vessel ( | 2008-09-11 |
20080221368 | Process for Preparing Polyoxymethylene Dimethyl Ethers from Methanol and Formaldehyde - A process for preparing tri- and tetraoxymethylene glycol dimethyl ether (POMDME | 2008-09-11 |
20080221369 | Process for the preparation of substituted phenols - A substituted phenolic compound is prepared by oxidizing a substituted diarylethane compound with oxygen in the presence of a nitrogen-containing cyclic compound, and treating the oxidized product with an acid. The nitrogen-containing cyclic compound includes, as a constituent of its ring, a skeleton represented by following Formula (I): | 2008-09-11 |
20080221370 | Process for Preparing Polyisobutyl-Substituted Cyclohexanols - The present invention relates to a process for preparing polyisobutyl-substituted cyclo-hexanols by hydrogenating polyisobutyl-substituted hydroxybenzenes. The invention further relates to the polyisobutyl-substituted cyclohexanols obtainable by this process and functionalization products thereof, and to their use for the surface modification of inorganic or organic material. | 2008-09-11 |
20080221371 | Method for the Separation of Polymeric By-Products from 1,4-Butynediol - The present invention relates to a process for purifying 1,4-butynediol, which comprises compressing 1,4-butynediol to from 50 to 1500 bar, depressurizing it, waiting for phase separation to occur after depressurization and separating off the bottom phase, and a process for the hydrogenation of 1,4-butynediol to 1,4-butenediol and 1,4-butanediol using the purified 1,4-butynediol. | 2008-09-11 |
20080221372 | Contamination Barrier - The present invention concerns a contamination barrier | 2008-09-11 |
20080221373 | Gas Clathrate Hydrate Compositions, Synthesis and Use - A solid clathrate hydrate comprising lactate anion and a calcium cation. The clathrate hydrate serves as a sponge that can be used to store a gas such as hydrogen, methane, oxygen, or carbon dioxide. The presence of carboxylate anion (lactate) stabilizes the clathrate so that it is solid and stable at relatively mild temperatures and pressures. | 2008-09-11 |
20080221374 | Method for the Production of Propene from Propane - A process for preparing propene from propane, comprising the steps:
| 2008-09-11 |
20080221375 | Catalyst Treatment Useful for Aromatics Conversion Process - A process for preparing a transalkylation catalyst, the catalyst itself, and a transalkylation process for using the catalyst are herein disclosed. The catalyst comprises rhenium metal on a solid-acid support such as mordenite, which has been treated with a sulfur-based agent. Such treatment reduces the amount of methane produced by metal hydrogenolysis in a transalkylation process wherein heavy aromatics like A | 2008-09-11 |
20080221376 | PROCESS FOR ISOMERIZING AROMATIC C8 COMPOUNDS IN THE PRESENCE OF A CATALYST COMPRISING A MODIFIED EUO ZEOLITE - A process for isomerizing a feed comprising at least one aromatic compound containing eight carbon atoms per molecule is carried out in the presence of a catalyst comprising at least one modified zeolite with structure type EUO, at least one binder and at least one metal from group VIII of the periodic table, said catalyst having been prepared using a process which comprises the following in succession:
| 2008-09-11 |
20080221377 | Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates - A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water. | 2008-09-11 |
20080221378 | Apparatus and Process for Cracking Hydrocarbonaceous Feed Utilizing a Pre-Quenching Oil Containing Crackable Components - An apparatus and process are provided for cracking hydrocarbons. Hot, cracked effluent is removed to a quench header where it is pre-quenched with an oil containing crackable components, e.g., 1000° F. | 2008-09-11 |
20080221379 | Composition And Method To Control Acid Rock Drainage - A composition to control acid rock drainage is provided. The composition includes a slurry made from water and solids, the solids containing powders of limestone, clay and magnesium oxide or magnesium hydroxide. In some instances, the slurry is thixotropic and contains between 10 to 75 weight percent of solid powders. The solid powders can include between 40 to 75 weight percent limestone, 10 to 35 weight percent clay and 10 to 30 weight percent magnesium oxide or a proportional concentration of magnesium hydroxide. | 2008-09-11 |
20080221380 | Soil decontamination by mechanically activated oxidation - A method of performing soil decontamination including mechanically mixing the soil with solid oxidant prior to any addition of water and until an exothermic reaction between the oxidant and contaminants within the soil occur, adding only necessary water to obtain an homogeneous mix between the soil and the oxidant, and mechanically mixing the soil with the oxidant and the water for a predetermined period of time to allow the oxidant to at least partially oxidize the contaminants. | 2008-09-11 |
20080221381 | Recharge Device for Brachytherapy of Tumors - A reloading device for brachytherapy of tumors is to be simplified in terms of the replacement of the radiation source at the irradiation site. At least two tubes are provided for receiving a longitudinally displaceable cable at the end of which a radiation source can be applied. The tubes can be connected, via a source replacement device and a shield, to a removable and adjustable distributor, from which lines lead to the tumor. By adjusting the distributor, the respectively desired line can be oriented to the respectively desired tube and in this way the desired radiation source can be introduced preferably step by step into the tumor. | 2008-09-11 |
20080221382 | Method and system of radiotherapy enhancement through cellular perturbation using ultrasound and microbubbles - An embodiment of the invention is related to a system for providing radiotherapy to a treatment region. The system includes a radiation source and a sound source. The radiation source is positioned to irradiate the treatment region. The sound source is positioned to provide ultrasound to the treatment region so that the treatment region is subject to coincidental treatment by irradiation and ultrasound. | 2008-09-11 |
20080221383 | TISSUE EXCISION DEVICES AND METHODS - A tissue excision device comprises a handle. In addition, the tissue excision device comprises an elongate tissue capture member extending from the handle. The tissue capture member has a longitudinal axis and comprises a free end distal the handle. Further, the free end of the tissue capture member includes a tip, a tissue capture recess, and at least one slot extending through the free end in the tissue capture recess. Still further, the tissue excision device comprises an elongate tubular cutting member coupled to the handle. The cutting member slidingly and coaxially receives the tissue capture member. In addition, the cutting member has a free end distal the handle that includes a cutting. | 2008-09-11 |
20080221384 | EXPANDABLE BRACHYTHERAPY APPARATUS AND METHODS FOR USING THEM - Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways. | 2008-09-11 |
20080221385 | HYPERTHERMIA TREATMENT DEVICE WITH X-RAY COMPUTED TOMOGRAPHY IMAGING - A medical technology device has an x-ray CT imaging system and a magnet system for generation of a radio-frequency alternating magnetic field for treatment of a tumor injected with ferrite nanoparticles, the x-ray CT system and the magnet system being combined to form a unitary structure. Imaging and tumor therapy can be conducted with one apparatus, and the monitoring of the course of the tumor therapy is simplified. | 2008-09-11 |
20080221386 | Devices for minimally invasive pelvic surgery - The invention, in various embodiments, provides systems, devices, and methods for treating urinary incontinence. | 2008-09-11 |
20080221388 | SIDE VIEWING OPTICAL FIBER ENDOSCOPE - An optical fiber conveys light from a source at a proximal end, to a distal end, where a piezoelectric material tube applies a force that causes the distal end of the optical fiber to scan in a desired pattern. Light from the distal end of the optical fiber passes through a lens system and is at least partially reflected by a reflective surface toward a side of the scope, to illuminate tissue within a patient's body. Light received from the internal tissue is reflected back either to collection optical fibers, which convey the light to proximally disposed optical detectors, or directly toward distal optical detectors. The optical detectors produce electrical signals indicative of an intensity of the light that can be used for producing an image of the internal tissue. The light received from the tissue can be either scattered, polarized, fluorescent, or filtered, depending on the illumination light. | 2008-09-11 |
20080221389 | Hand assisted laparoscopic seal assembly with deflection feature - A seal assembly for permitting hand assisted laparoscopic procedures is disclosed. The seal assembly includes a seal cap having a seal positioned within a housing. The housing includes a lower seal ring having a track which supports an upper seal ring for relative rotational motion. The seal is supported between the upper seal ring and the lower seal ring for rotation between an open orientation and a closed orientation. A ratchet mechanism is provided for controlling motion of the upper seal ring relative to the lower seal ring. The ratchet mechanism includes a deflection feature and a series of gear teeth, wherein the series of gear teeth are oriented to engage the deflection feature. | 2008-09-11 |
20080221390 | Medico-Technical Device Comprising a Self-Lubricating Element - The invention describes a medico-technical device adapted to be engaged with a human or animal body and comprising a self-lubricating element exposed to internal friction in the device. | 2008-09-11 |
20080221391 | DIRECT DRIVE INSTRUMENTS AND METHODS OF USE - Disclosed herein are various instruments, systems, and methods of use. The instruments can have various control members and/or handles for controlling various degrees of freedom. In addition, the control members can include various control mechanisms for transferring user inputs from a handle to a distal portion of the instrument. In one aspect, an instrument can comprise a control member and a catheter. The catheter can be adjustably and/or detachably connected to the control member. | 2008-09-11 |
20080221392 | Method and Devices for Minimally Invasive Arthroscopic Procedures - A device with a flexible member configured to take on a curvilinear profile can be used to perform arthroscopic procedures. The device can be used to perform such procedures through two access ports, providing visualization and access to the entire site of the procedure, e.g. hip joint, without switching cannulated access portals or providing additional access portals. | 2008-09-11 |
20080221393 | MEDICAL DEVICE WITH ARTICULATING SHAFT - A medical device ( | 2008-09-11 |
20080221394 | TISSUE RETRACTOR - Methods and devices for minimally invasive surgery in a patient. A tubular body is disclosed which includes in its side wall a plurality of longitudinal passages. Elongated blocking members are also disclosed which are inserted into the passages. The elongated blocking members block deflected interfering tissue during the surgery. | 2008-09-11 |
20080221395 | SELF-ORGANIZING MAPS IN CLINICAL DIAGNOSTICS - The present invention provides methods for the diagnosis of a disease or condition in an individual. The methods employ a primary self-organizing map trained with biological marker profiles from tissues having known diseases or conditions, in combination with a secondary self-organizing map which displays a representation of a subset of the primary self-organizing map with sample data obtained from an individual in need of diagnosis. A result is prepared from the secondary SOM(s) that reveals the extent of similarity between the known diseases or conditions with the sample data set of the individual. The result can be provided to a practitioner to aid in the diagnosis of the individual. | 2008-09-11 |
20080221396 | Method and System for Monitoring Medical Treatment - An electronic network is disclosed for effectively providing a technique to administer medical treatment. The technique pertains to at least one patient and at least one unit for medical treatment. The technique involves receiving patient data and unit data and evaluating at least the patient data and/or unit data to determine whether a match with preexisting data exists, which thereby generates an indication to the user to not proceed with the medical treatment in the absence of such a match. | 2008-09-11 |
20080221397 | Defibrillator Patient Monitoring Pod - A patient parameter monitoring pod in embodiments of the teachings may include one or more the following features: (a) portable housing containing a power supply, (b) a patient parameter module connectable to a patient via lead cables to collect patient data, the patient data including at least one vital sign, (c) a transceiver adapted to wirelessly transmit the patient data to a defibrillator, (d) a data port adapted to supply the patient data via a direct electrical connection to the defibrillator, and (e) a carrying handle extending from the housing proximate a patient lead cable port that permits connection of the lead cables to the pod, the carrying handle positioned to protect the patient lead cable port and the patient lead cables attached to the port from direct impact. | 2008-09-11 |
20080221398 | Apparatus and Method for Monitoring and/or Load Applied to a Mammal - Apparatus is disclosed for monitoring strain and/or load applied to the body of a vertebral mammal. The apparatus includes means ( | 2008-09-11 |
20080221399 | MONITOR FOR MEASURING VITAL SIGNS AND RENDERING VIDEO IMAGES - The invention features a vital sign monitor that includes: 1) a sensor component that attaches to the patient and features an optical sensor and an electrical sensor that measure, respectively a first and second signal: and 2) a control component. The control component features: 1) an analog-to-digital converter configured to convert the first signal and second signal into, respectively, a first digital signal and a second digital signal; 2) a CPU configured to operate an algorithm that generates a blood pressure value by processing with an algorithm the first digital signal and second digital signal; 3) a display element; 4) a graphical user interface generated by computer code operating on the CPU and configured to render on the display element the blood pressure value; and 5) a software component that renders video images on the display element. To capture video and audio information, the device further includes both a digital camera and a microphone. | 2008-09-11 |
20080221400 | METHOD AND SYSTEM FOR MEASURING AND RANKING AN "ENGAGEMENT" RESPONSE TO AUDIOVISUAL OR INTERACTIVE MEDIA, PRODUCTS, OR ACTIVITIES USING PHYSIOLOGICAL SIGNALS - A system and method for calculating an engagement value by quantifying an amount that a user is acting without thinking considering brainwaves and a heart rate can be used to compare media based on an individual or a group of individuals. Events of the media can be contrasted and compared by the engagement value as well. Statistical measurements may be taken to improve media. | 2008-09-11 |
20080221401 | IDENTIFICATION OF EMOTIONAL STATES USING PHYSIOLOGICAL RESPONSES - The invention provides a method for automatically identifying emotional states of a person in real-time based on physiological responses by exposing a person to a stimulus, measuring the person's physiological response to the stimulus, and comparing the measured physiological response to a known baseline physiological. The deviation of the measured physiological response from the baseline physiological response is determinative of the emotional state. | 2008-09-11 |
20080221402 | INTEGRATED PATIENT DIAGNOSTIC AND IDENTIFICATION SYSTEM - A small integrated diagnostic and identification system is disclosed that solves several problems associated with current sensory systems. The diagnostic and identification system comprises a bracelet with an identification mechanism that is difficult to remove and has a lock. Further, the diagnostic and identification bracelet comprises a microprocessor which communicates with various physiologic sensors wherein said physiological sensors are substantially within said bracelet. Alternatively some of the sensors may be mounted outside the bracelet and means are provided for communicating data from the outside mounted sensors to the bracelet. The physiologic sensors either routinely, automatically monitor an individual's physiology or monitor the physiology based on a user request. The resulting physiology data from each sensor is combined via a single output and displayed on a display device. The present invention may be integrated with a record management system to share and store an individual's records. | 2008-09-11 |
20080221403 | Reconfigurable Garment Definition and Production Method - Computer-aided design and manufacture software and hardware automate garment and fashion definition and production. Configurable garment includes ornamental element, pattern display, and personal identifier and wireless sensor electronics. | 2008-09-11 |
20080221404 | MULTIFUNCTION HEALTH APPARATUS - The present invention provides a multifunction health device, which comprises a meter and a platform. The meter has two electrodes arranged separately at its two sides or both arranged at its one side, and the meter has another electrode arranged in its bottom. The platform has four electrodes arranged in its top face, and a pressure sensor arranged in its inside. With or without some parts assisting, the single use of the meter can function as an ECG detector, a TENS machine, a thermometer, and a first sphygmomanometer. Connecting with the platform, the meter and the platform can function as an ECG detector, a weight scale, and a body composition estimator. Further, the meter can alternatively connect with a chassis thus functioning as a second sphygmomanometer, a stethoscope, a glucose meter, or a pulse oximeter. | 2008-09-11 |
20080221405 | Method for assessing subsurface irritation of skin - A method for determining skin irritation is provided. The method uses a source of cross-polarized light to illuminate and area of skin. The cross-polarized light is used to detect subsurface indicators of skin irritation such as erythema, inflammation, dryness, or innervation. The subsurface indicator is then assigned a score. | 2008-09-11 |
20080221406 | Method and apparatus for estimating water reserves - A system and method are provided for a water reserve index. The method includes determining a lean water fraction of tissue for at least one tissue site and determining skin thickness for the at least one tissue site. The lean water fraction and skin thickness are combined to produce a water reserve estimate. | 2008-09-11 |
20080221407 | Method for evaluating skin hydration and fluid compartmentalization - There is provided a system and method for evaluating skin hydration and fluid compartmentalization. The system includes a microneedle array configured to extract fluid from an interstitial space and a pressure sensor configured to measure a pressure differential between the interstitial space and ambient pressure during extraction of the fluid. A processor coupled to the pressure sensor is configured to compute a hydration index based on the pressure differential. A display coupled to the processor is configured to display the hydration index. | 2008-09-11 |