36th week of 2009 patent applcation highlights part 44 |
Patent application number | Title | Published |
20090221746 | Neutralization Process - The invention relates to a neutralization process in which at least one ethylenically unsaturated carboxylic acid is preneutralized at least partly with a base, wherein the preneutralized solution is divided into at least two part-solutions and at least one part-solution is aftertreated so as to form part-solutions with different degree of neutralization and/or solids content, and also to an apparatus for carrying out the process. | 2009-09-03 |
20090221747 | PROCESS OF SEPARATING GUN PROPELLANT COMPONENTS AND USEFUL BYPRODUCTS THEREOF - Methods for the separation of targeted components from gun propellant formulations. In particular, the methods separate targeted components in a usable/useful form. Preferred methods are directed to the separation of nitrocellulose, nitroguanidine and/or nitroglycerine from a formulation containing one or more of these components. | 2009-09-03 |
20090221748 | COATING COMPOSITIONS COMPRISING A POLYMER CONTAINING AN OLIGOMERIC MACROMONOMER - The present invention is directed to a coating composition comprising a polymer that comprises an oligomeric macromonomer and a core from which the oligomeric macromonomer extends, wherein the oligomeric macromonomer comprises reactive functional groups and has an average functionality ranging from 1.0 to 30, and wherein the core is <10 weight % of the total polymer weight. | 2009-09-03 |
20090221749 | POLYMER HAVING NAPHTHYL GROUP AND PRODUCING METHOD THEREOF - The object of the present invention is to provide a polymer excellent in transparency and heat resistance. | 2009-09-03 |
20090221750 | Thermoplastic Resin, Method for Producing Same and Molding Material - A thermoplastic resin comprising a block copolymer or a graft copolymer possessing (A) a crystalline hydrogenated norbornene ring-opening polymer unit and (B) a non-crystalline polymer unit having a glass transition temperature of 40 to 300° C.; A method for producing thermoplastic resin comprising hydrogenating a block copolymer or a graft copolymer possessing a norbornene ring-opening polymer unit (C) and a polymer unit (D) which is converted into the above-mentioned non-crystalline polymer unit (B) after hydrogenation, in the presence of a hydrogenation catalyst; and a molding material comprising the thermoplastic resin are provided. The thermoplastic resin of the present invention excels in transparency, heat resistance, and mechanical strength. | 2009-09-03 |
20090221751 | Rubber Mixtures - Rubber mixtures, including at least one rubber, a filler, an organosilicon compound of the formula I | 2009-09-03 |
20090221752 | FOULING RELEASE COMPOSITION - The present invention relates to a fouling release composition comprising a cured or crosslinked polysiloxane and a fluorinated polymer or oligomer. The present invention also relates to the use of the said fouling release composition in fouling release coatings for application to articles submerged in seawater. | 2009-09-03 |
20090221753 | Method of Melt Blending Curable Polymer Compositions Using Silicone Hydrides - Provided in one aspect is a method of melt blending comprising providing an extruder possessing addition points from a zero point to a 100 point the length of the extruder; adding at least one thermoplastic and at least one curable polymer at the zero to 10 point of the extruder; adding at least one silicone hydride at the 5 to 30 point of the extruder; adding at least one metal catalyst at the 20 to 60 point of the extruder, with the proviso that the metal catalyst is added at least 5 points farther down the extruder than the silicone hydride. Provided in another aspect is a hydrosilylation curative composition comprising a silicone hydride having the formula | 2009-09-03 |
20090221754 | POLYMER COMPOSITIONS OF BROMOSTYRENES HAVING CONTROLLED MOLECULAR WEIGHT - A controlled molecular weight polymer of styrene is provided having bromine substituted thereon. Control of molecular weight is achieved by the use of alphα-methyl styrene dimer as a chain transfer agent. The brominated polymer of styrene is useful as a flame retardant, particularly for polyamides giving improved properties including color retention after molding. | 2009-09-03 |
20090221755 | RESIN COMPOSITION - A resin composition includes polylactic acid resin, a plastic resin superior in heat resistance to the polylactic acid resin, and a nucleating agent that promotes crystallization of the polylactic acid resin, with the nucleating agent being a soluble azo lake pigment. The plastic resin superior in heat resistance to the polylactic acid resin is one which has a flexural modulus of elasticity no lower than 1000 MPa at 80° C. | 2009-09-03 |
20090221756 | Block Copolymers Useful as Tensioning Agents - The invention concerns a novel linear block copolymer, which can be useful as surface tensor. The invention also concerns non-cosmetic compositions comprising the copolymer. The copolymer comprises in particular a styrene block and a ethyl acrylate or ethyl methacrylate block. | 2009-09-03 |
20090221757 | POLYMERS CONTAINING AN OLIGOMERIC MACROMONOMER - The present invention is directed to a polymer that comprises an oligomeric macromonomer and a core from which the oligomeric macromonomer extends, wherein the oligomeric macromonomer comprises reactive functional groups and has an average functionality ranging from 1.0 to 30.0, and wherein the core is <10 weight % of the total polymer weight. The present invention is also directed to a method for making the same. | 2009-09-03 |
20090221758 | PERFLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE HEREOF - The present invention provides a perfluoroelastomer composition comprising: a perfluoroelastomer having a nitrogen-containing curing site; and a catalyst mixture comprising: a tertiary amine; and an organic dicarboxylic acid represented by general formula (1) or (2) in an amount of 0.4 to 2 mol per mol of the tertiary amine: | 2009-09-03 |
20090221759 | Oligomers And Polymers Containing Sulfinate Groups And Method For The Production Thereof - The invention relates to novel polymers or oligomers containing at least sulfinate groups (P-(SO2)nX, X=1-(n=1), 2-(n=2) or 3-(n=3) valent metal cation or H+ or ammonium ion NR4+ where R=alkyl, aryl, H), which are obtained by completely or partially reducing polymers or oligomers containing at least SO2Y-groups (Y═F, Cl, Br, I, OR, NR2 (R=alkyl and/or aryl and/or H), N-imidazolyL N-pyrazolyl) by means of suitable reducing agents in a suspension or in a solution form | 2009-09-03 |
20090221760 | Diphenylamine functionalization of poly-alpha-olefins - Provided is a process for making a diphenylamine-functionalized poly-α-olefin. The process has the following step: reacting an amount of a poly-α-olefin having a terminal double bond with a diphenylamine in the presence of a catalyst. The poly-α-olefin has a terminal double bond having a number average molecular weight of 120 to 600. The ratio of poly-α-olefin to diphenylamine is 1.0:1.0 to 10.0:1.0. Provided is also a diphenylamine-functionalized poly-α-olefin product. | 2009-09-03 |
20090221761 | PROCESS FOR REMOVING RESIDUAL VOLATILE MONOMERS FROM A POLYMER IN POWDER FORM - A process for purifying a polymer containing residual volatile monomers by drying the polymer powder under vacuum at a pressure and at a temperature which allows the vaporization of the residual monomers and optionally de-aggregating by sieving. | 2009-09-03 |
20090221762 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS - The invention concerns compounds, oligomers, and polymers that contain: (I), (II), (III), or (IV) groups; where “-” indicates points of attachment. | 2009-09-03 |
20090221763 | Chemical Defunctionalization of Polymeric Alkylenedioxyheterocyclics - A method for preparing a defunctionalized alkylenedioxyheterocycle polymer or copolymer involves providing a polycarboxylic acid derivative functionalized alkylenedioxyheterocycle polymer or copolymer and transforming the polymer or copolymer into a defunctionalized alkylenedioxyheterocycle polymer or copolymer which is a polyhydroxy, polythiol, polyamino, or polycarboxylic acid functionalized alkylenedioxyheterocycle polymer or copolymer. The monomers, homopolymers and copolymers for use in the method are new compositions of matter. The polymers containing polycarboxylic acid derivative functionalized alkylenedioxyheterocycle units are soluble polymers which are defunctionalized to yield insoluble polyhydroxy, polythiol, polyamino, or polycarboxylic acid functionalized alkylenedioxyheterocycle polymers. These polymers can be cast as films for use as: hole transport layers in organic light emitting diodes; active electrochrome in electrochromic windows, mirrors and displays; field effect transistors, supercapacitors, batteries, photovoltaic cells, and other electronic components; electronic paper; anti-stat conductors; and transparent conductors. | 2009-09-03 |
20090221764 | Asymmetrically-Functionalized Nanoparticles Organized in One-Dimensional Chains - The invention provides methods and compositions having one-dimensional nanoparticle chains. A one-dimensional nanoparticle chain can comprise a linear substantially non-crosslinked polymer having pendant groups and asymmetrically functionalized nanoparticles attached to the polymer through the pendant groups. Additionally, an asymmetrically functionalized nanoparticle can comprise a nanoparticle core having an outer surface, a primary group of first ligands attached to a substantially continuous primary region of the outer surface, and a secondary group of second ligands attached to a substantially continuous secondary region of the outer surface, such that the primary group of first ligands and the secondary group of second ligands comprise a different ligand population. | 2009-09-03 |
20090221765 | POLYMER FOR USE IN A TUNEABLE DIFFRACTION GRATING (TDG) MODULATOR - The present invention relates to a tuneable diffraction grating modulator based on the principle of total internal reflection comprising an elastomer as a deformable layer to be modulated in a nonuniform electric field. | 2009-09-03 |
20090221766 | STEREOSELECTIVE REDUCTION OF A MORPHINONE - A synthetic method is provided, wherein the method comprises stereoselectively reducing a ketone of a morphinone to form a reduced morphinone and optionally covalently attaching a water soluble polymer to the reduced morphinone. | 2009-09-03 |
20090221767 | NOVEL USE OF A COPOLYMER COMPRISING POLYAMIDE BLOCKS AND POLYETHER BLOCKS ORIGINATING AT LEAST PARTIALLY FROM POLYTRIMETHYLENE ETHER GLYCOL - Use of a copolymer comprising polyamide blocks and polyether blocks of the general formula (I) | 2009-09-03 |
20090221768 | METHOD FOR THE ESTERIFICATION OF TEREPHTALIC ACID WITH BUTANEDIOL, METHOD FOR THE MANUFACTURE OF POLYBUTYLENE TEREPHTALATE AND A DEVICE THEREFOR - The present invention relates to an improved method for the esterification of terephthalic acid with 1,4-butanediol, an improved method for the manufacture of polybutylene terephtalate as well as reactors and devices that are suited for the application in this method. | 2009-09-03 |
20090221769 | Method for the preparation of linera alpha-olefins and reactor system therefor with improved disposal of high molecular weight oligomers - The present invention relates to a method for processing high molecular weight oligomer waste products formed during the production of linear alpha-olefins by oligomerization of ethylene in a reactor in the presence of a solvent and a catalyst, characterized in that the high molecular weight oligomers are separated in a separation unit from a product stream of the reactor comprising the solvent, the catalyst, linear alpha-olefins and high molecular weight oligomers having a solidification temperature in the range of about 60-100° C., then diluted with a dilution medium and heated to about 130° C. to about 200° C., the diluted high molecular weight oligomers are then transferred to a disposal device, wherein at least some of the dilution medium may be recovered and recycled for addition to the dilution medium. | 2009-09-03 |
20090221770 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME - Metal complexes comprising certain polydentate heteroatom containing ligands, catalysts, and coordination polymerization processes employing the same are suitably employed to prepare polymers having desirable physical properties. | 2009-09-03 |
20090221771 | PROCESS FOR POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE - Provided is a process for polymerization and copolymerization of ethylene, specifically comprising carrying out polymerization or copolymerization ethylene in the presence of (a) a solid complex titanium catalyst which is produced by the process comprising: (i) preparing a magnesium compound solution by contacting a halogenated magnesium compound and an alcohol for allowing a reaction; (ii) reacting the resulted magnesium compound solution with an ester compound having at least one hydroxyl group and a silicon compound having at least one alkoxy group; (iii) reacting the resulted solution with a mixture of a titanium compound and a silicon compound to obtain a solid titanium catalyst component; (iv) washing the resulted solid titanium catalyst component with a halogenated saturated hydrocarbon compound; and (v) further reacting the washed solid titanium catalyst component with a titanium compound to obtain a solid complex titanium catalyst, and (b) an organometallic compound from Group II or III of Periodic table of elements. According to the present invention, it is possible to provide a process for polymerization or copolymerization of ethylene in which the catalyst activity is improved and a polymer of high bulk density is provided, with the use of a catalyst prepared by a simple process. | 2009-09-03 |
20090221772 | Metallocene Compounds - A bridged metallocene compound of formula (I) wherein: M is a transition metal; X, is a hydrogen atom, a halogen atom, or a hydrocarbon group optionally containing hetematoms; L is a divalent bridging group; R | 2009-09-03 |
20090221773 | METHODS FOR DIRECT ATTACHMENT OF POLYMERS TO DIAMOND SURFACES AND DIAMOND ARTICLES - A method for forming a polymer on a substrate is disclosed. The method may include providing a substrate having a substrate surface, the substrate surface being at least partially hydrogen-terminated and reacting the substrate surface in a solution comprising at least one radical initiator and at least one monomer to form a polymer on the substrate surface. The monomer may comprise at least one of a monofunctional monomer and a polyfunctional monomer. A stationary phase for use in separation applications such as chromatography and solid-phase extraction is also disclosed. The stationary phase may include a plurality of diamond bodies and a polymeric compound covalently bonded to at least a surface portion of the plurality of diamond particles. | 2009-09-03 |
20090221774 | DIENE POLYMER AND PRODUCTION PROCESS THEREOF - A polymer comprising a unit represented by the following formula (1); and a process for producing the polymer comprising the step of polymerizing a diene compound such as 9,9-diallylfluorene in the presence of a polymerization catalyst formed by contacting a nickel compound with an organoaluminum compound and/or a boron compound: | 2009-09-03 |
20090221775 | Utilization Of Linear Alpha Olefins In The Production Of Metallocene Catalyzed Poly-Alpha Olefins - The invention is directed to a process for the preparation of lubricant base stocks by contacting alphaolefin feedstocks with single-site metallocene catalysts and recycling unconverted monomers, characterized by a purge step in the recycle. | 2009-09-03 |
20090221776 | POLYMERIZATION OF FLUOROPOLYMERS USING NON-FLUORINATED SURFACTANTS - The present invention relates to a method for the polymerization in an aqueous medium of monomers, and especially of fluoromonomers, using non-fluorinated surfactants; and the fluoropolymers formed therefrom. Specifically, the method of the polymerization uses one or more non-fluorinated surfactants selected from the group consisting of polyvinylphosphonic acid, polyacrylic acids, polyvinyl sulfonic acid, and salts thereof. Additionally, the use of polyvinylphosphonic acid, polyacrylic acids, polyvinyl sulfonic acid as surfactants in aqueous free radical polymerization is also novel. | 2009-09-03 |
20090221777 | PHOTOSENSITIVE RESIN COMPOSITION - Disclosed is a photosensitive resin composition comprising (A) a polyimide resin, (B) a photo-acid generator, and (C) a crosslinking agent having an alkoxyalkylated amino group. | 2009-09-03 |
20090221778 | FILM - A file is formed by coating a substrate with a film-forming composition including a compound having an alicyclic hydrocarbon structure and irradiating the coated composition with microwaves having a frequency of 5.8 GHz. An insulating film is formed by irradiating a film including a compound having a siloxane structure with microwave having a frequency of 5.8 GHz. These films possess excellent film properties such as dielectric constant and mechanical strength. | 2009-09-03 |
20090221779 | FILM FORMING COMPOSITION, INSULATING FILM, AND ELECTRONIC DEVICE - A film forming composition is provided that includes a compound represented by Formula (1) below and/or a polymer polymerized using at least a compound represented by Formula (1) below | 2009-09-03 |
20090221780 | PROCESS FOR STORING A MONOMER PHASE WHICH IS LIQUID UNDER THE CONDITIONS OF STORAGE - A process for storing a monomer phase which is liquid under the conditions of storage and comprises methacrylic monomers to an extent of ≧95% by weight and has been obtained by condensation out of a gaseous phase or by melting a crystalline phase, in a storage vessel, in which polymer of the monomer present in dissolved form in the liquid monomer phase is removed therefrom on the route from its generation into the storage vessel, and also a process for withdrawing liquid monomer phase from the storage vessel in which polymer of the monomer present in dissolved form in the monomer phase is likewise removed. | 2009-09-03 |
20090221781 | POLYESTER BASED DEGRADABLE MATERIALS AND IMPLANTABLE BIOMEDICAL ARTICLES FORMED THEREFROM - A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of said first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of said second diacid, wherein said second diacid is different from said first diacid. Prepolymers produced from such processes and articles formed therefrom are also described. | 2009-09-03 |
20090221782 | Conductive Polyolefins with Good Mechanical Properties - Processes for preparing reinforced polymeric material and the materials formed therefrom are discussed herein. The processes generally include providing a polymeric matrix, providing single-wall carbon nanotubes (SWNT) or multiple-wall carbon nanotubes (MWNT), purifying by the nanotubes in a single step of dissolving a support and catalyst particles with an agent appropriate to the nature of the support to form a purified support, functionalising the purified support by reaction with an alkylamine to form a functionalized support, dispersing the nanotubes in the polymeric matrix by mixing in the molten state to form a mixture and optionally orienting the mixture by stretching. | 2009-09-03 |
20090221783 | Encapsulation resins - Curable polyorganosiloxanes are provided that cure in the absence of a hydrosilylation catalyst. The cured polyorganosiloxanes have increased stability and can be used as encapsulation resin is at a temperature far lower than 300° C., have excellent light transmission properties (colorless transparency) in a wavelength region of from ultraviolet light to visible light, light resistance, heat resistance, resistance to moist heat and UV resistance, and do not generate cracks and peeling even in use over a long period of time. | 2009-09-03 |
20090221784 | BIODEGRADABLE POLYURETHANES - A method for preparing biodegradable polyurethanes includes contacting a flowable quasi-pre-polymer including free aliphatic polyisocyanate compounds with a polyester polyol hardener having a functionality of at least two to form a reactive liquid mixture. The quasi-prepolymer can, for example, be formed by contacting a polyisocyanate component comprising at least one aliphatic polyisocyanate compound with a polyol component comprising at least one polyol compound to form an adduct of the polyisocyanate component and the polyol component wherein a sufficient excess of the polyisocyanate component is used to form the quasi-prepolymer. | 2009-09-03 |
20090221785 | PRODUCTION OF NON-SOLID-STATED POLYESTER PARTICLES HAVING SOLID-STATED PROPERTIES - A process for producing non-solid-stated polyester polymer particles having one or more properties similar to polyester polymer particles that have undergone solid-state processing. | 2009-09-03 |
20090221786 | Taxol immunoassay - Novel conjugates of taxol and novel taxol immunogens derived from the 9 and 7 positions of taxol and monoclonal antibodies generated by these taxol linked immunogens are useful in immunoassays for the quantification and monitoring of taxol in biological fluids. | 2009-09-03 |
20090221787 | Production Of Monomer, Oligomer And Polymer Phosphonic Acid Esters And Phosphonic And Sulphonic Acids By A Nucleophile Aromatic Substitution - The invention relates to producing monomer, oligomer and polymer non-fluorinated, partially fluorinated or perfluorinated sulphonic acids by reacting halogenated, low-molecular weight, oligomer or macromolecular arenes with (hydrogen) sulphites, dithionites, sulphides or other reducing sulfur salts, possibly by oxidising sulphur-containing arene intermediates which are formed at a sulphur oxidation degree less than +6 by means of appropriate oxidation agents with formation of corresponding sulphonate functional groups (sulphonic acid, sulfohalogenide, sulphonamide and sulphonic acid ester groups). The invention also relates to a method for producing monomer, oligomer or polymer non-halogenated, partially halogenated or perhalogenated phosphonic acid esters and the derivatives thereof (for example, a free phosphonic acid or a phosphonic acid salt) by a nucleophile aromatic substitution (Michaelis-Becker-reaktion, complete or partial substitution of halogenide functional groups by phosphate functional groups (phosphonic acid esters, phosphonic acid amides, phosphonic acids, phosphonic acid salts, phosphonic acid halogenides). Said invention also relates to a method for producing polymer or ionomer non-halogenated, partially halogenated or perhalogenated containing (CF | 2009-09-03 |
20090221788 | Apparatus and Method for Degassing Polymer Powder - The present invention relates to an apparatus for degassing polymer powder comprising a chamber having a first end and a second end opposite to each other, said chamber being equipped with at least one powder inlet and at least one gas outlet at the first end and with at least one powder outlet and at least one gas inlet at the second end, and a valve provided with a powder entry and a powder exit and arranged at the powder outlet of said chamber. The apparatus is characterised in that said chamber is equipped with a gas line joining a gas exit of the valve to the inside of the chamber at a position that is at a distance h | 2009-09-03 |
20090221789 | Crystalline Polypeptides - Crystalline formulations of therapeutic peptides, along with methods for making and using the same, are provided. | 2009-09-03 |
20090221790 | METHOD FOR STABILIZATION OF PROTEINS USING NON-NATURAL AMINO ACIDS - The present invention provides a method for producing modified stable polypeptides introducing at least one non-natural amino acid into the hydrophobic region of the polypeptide. The thermal and chemical stability of such polypeptides is improved compared to those properties of its corresponding wild type proteins. | 2009-09-03 |
20090221791 | Composition and Method for the Release of Protected Peptides from a Resin - The present invention provides a composition and a method for cleaving a peptide from a solid support resin. Hydrochloric acid in an organic water miscible solvent is used to cleave the peptide-resin attachment. Optionally, trifluoroethanol or hexafluoroisopropanol may be added to the cleavage composition to improve results. When using the present cleavage composition, an evaporation or other step to remove carboxylic byproducts is not necessary following the cleavage reaction. After the resin is filtered out of the cleavage mixture, the peptide may be immediately precipitated with water. | 2009-09-03 |
20090221792 | Microwave-Assisted Peptide Synthesis - An instrument and associated method are disclosed for the accelerated synthesis of peptides by the solid phase method. The instrument includes a microwave cavity, a microwave source in communication with the cavity, a column in the cavity formed of a material that is transparent to microwave radiation, a solid phase peptide support resin in the column, respective filters for maintaining the solid phase support resin in the column, a first passageway for adding starting compositions to the column, a second passageway for removing compositions from the column, and a third passageway for circulating compositions from the column into the third passageway and back to the column. | 2009-09-03 |
20090221793 | PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE - The invention relates to a process for preparing a conjugate that includes a pentopyranosyl nucleic acid and a biomolecule. The process includes the steps of providing a pentopyranosyl nucleic acid having at least two pentopyranosyl nucleotide subunits that are covalently linked between carbon 4 and carbon 2 of their respective pentopyranosyl rings. The pentopyranosyl nucleic acid also has an electrophilic reactive group. A biomolecule having a nucleophilic reactive group is also provided. The electrophilic reactive group of the pentopyranosyl nucleic acid and the nucleophilic reactive group of the biomolecule are reacted to form a covalent bond. | 2009-09-03 |
20090221794 | Human Protooncogene and Protein Encoded By Same - Disclosed are a novel protooncogene and a protein encoded by the same. The protooncogene of the present invention may be effectively used for diagnosing various cancers including breast cancer, leukemia, uterine cancer, malignant lymphoma, etc. | 2009-09-03 |
20090221795 | ACTIVE TRUNCATED FORM OF THE RNA POLYMERASE OF FLAVIVIRUS - The isolation and purification of two domains from a from a | 2009-09-03 |
20090221796 | Heteromeric taste receptors - Heteromeric taste receptors are provided. These receptors comprise a first polypeptide containing extracellular domains and transmembrane domains wherein the extracellular domains are at least 95% identical to the extracellular domains of specific T1R2 polypeptides and the transmembrane domains are at least 95% identical to the corresponding transmembrane domains of the specific T1R2 polypeptide or a different GPCR; and a second polypeptide comprising extracellular and transmembrane domains wherein the extracellular domains are at least 95% identical to the extracellular domains of specific T1R3 polypeptides and the transmembrane domains are at least 95% identical to the corresponding transmembrane domains of the specific T1R3 polypeptide or a different GPCR. | 2009-09-03 |
20090221797 | HETEROMERIC TASTE RECEPTORS - Heteromeric taste receptors are provided. These receptors comprise a first polypeptide which comprises extracellular and transmembrane domains wherein the transmembrane domains are at least 95% identical to the transmembrane domains of specific T1R1 polypeptides, and the extracellular domains are at least 95% identical to the corresponding extracellular domains of the specific T1R1 polypeptide or a different GPCR; and a second polypeptide which comprises extracellular and transmembrane domains wherein the transmembrane domains are at least 95% identical to the transmembrane domains of specific T1R3 polypeptides, and the extracellular domains are at least 95% identical to the corresponding extracellular domains of the specific T1R3 polypeptide or that of a different GPCR. | 2009-09-03 |
20090221798 | HETEROMERIC TASTE RECEPTORS - Heteromeric taste receptors are provided. These receptors comprise a first polypeptide which comprises extracellular and transmembrane domains wherein the transmembrane domains are at least 95% identical to the transmembrane domains of specific T1R2 polypeptides, and the extracellular domains are at least 95% identical to the corresponding extracellular domains of the specific T1R2 polypeptide or a different GPCR; and a second polypeptide which comprises extracellular and transmembrane domains wherein the transmembrane domains are at least 95% identical to the transmembrane domains of specific T1R3 polypeptides, and the extracellular domains are at least 95% identical to the corresponding extracellular domains of the specific T1R3 polypeptide or that of a different GPCR. | 2009-09-03 |
20090221799 | Novel Fluorescent and Colored Proteins, and Polynucleotides That Encode These Proteins - The subject invention provides new fluorescent and/or colored proteins, and polynucleotide sequences that encode these proteins. The subject invention further provides materials and methods useful for expressing these detectable proteins in biological systems. | 2009-09-03 |
20090221800 | Method for the Production of Recombinant Proteins - The present invention relates to a process for the production of recombinant polypeptides in leukocytes. | 2009-09-03 |
20090221801 | Adsorbents for Protein Purification - Use of an affinity adsorbent for the separation, removal, isolation, purification, characterisation, identification or quantification of a proteinaceous material, wherein the affinity adsorbent is a compound of formula (III), wherein R | 2009-09-03 |
20090221802 | SOLUBLE ZALPHA11 CYTOKINE RECEPTORS - Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zalpha11 receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block zalpha11 Ligand activity in vitro and in vivo, and may be used in conjunction with zalpha11 Ligand and other cytokines to selectively stimulate the immune system. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto. | 2009-09-03 |
20090221803 | MODULATION OF ANTIBODY EFFECTOR FUNCTION BY HINGE DOMAIN ENGINEERING - The present invention relates to novel molecules (Fc variants) comprising at least one antigen binding region and an Fc region that further comprises a modified hinge which alters the binding of Fc to one or more Fc ligand (e.g., FcγRs) and/or modulates effector function. More specifically, this invention provides Fc variants that have modified binding affinity to one or more FcγR and/or CIq. Additionally, the Fc variants have altered antibody-dependent cell-mediated cytotoxicity (ADCC) and/or complement dependent cytotoxicity (CDC) activity. The invention further provides methods and protocols for the application of said Fc variants particularly for therapeutic purposes. | 2009-09-03 |
20090221804 | GBS Toxin Receptor Compositions and Methods of Use - Methods are provided for preventing or attenuating pathoangiogenic conditions by administering at least one GBS toxin receptor polypeptide or at least one immunogenic fragment thereof. Also provided are a composition that includes a GBS toxin receptor polypeptide and a method for making such a composition. In another embodiment of the invention, immunized animals also receive GBS toxin, immunocompatible antibodies to the GBS toxin receptor, and/or expanded autologous T cells to the GBS toxin receptor. Also included in this invention are methods of identifying additional GBS toxin receptors. | 2009-09-03 |
20090221805 | Complex polymere amphiphile-PDGF - Physically and chemically stable, water-soluble, amphiphilic polymer-PDGF complex, characterized in that the amphiphilic polymers include a hydrophilic polymeric backbone functionalized with hydrophobic substituents and hydrophilic groups. | 2009-09-03 |
20090221806 | Method for Producing a Beta-1,3-Glucan With Improved Characteristics - In this process for preparing a β-1,3-glucan, the glucan-containing matrix is treated with a protein having β(1,3)-glucanase activity, wherein the concentration of the glucanase amounts from 0.001 to 3.0% by weight. The glucan-containing matrix can be a fermentation broth, a culture medium or a suspension, where appropriate containing unsolved solids, cell constituents and/or cell fragments, or else a mycelium, a hydrocolloid or a powder preparation having a solvent proportion of from 20 to 99.9% by weight. The duration of the enzymatic treatment should be between 15 minutes and 24 hours and the treatment should be carried out continuously. The invention also envisages the glucan-containing matrix being filtered or centrifuged, after it has been treated enzymatically, and the glucan finally being separated off. A β-1,3-glucan which has been prepared in this way and which exhibits, for example, improved solubility in cold water, reduced proportions of insoluble constituents, an increased viscosity or improved filterability, is also claimed. A solid formulation and the use of these glucans for cosmetic applications, foodstuffs or oil production are also coclaimed. | 2009-09-03 |
20090221807 | 2' Deoxy-2'-Alkylnucleotide Containing Nucleic Acid - 2′-deoxy-2′-alkylnucleotides useful for stabilizing enzymatic nucleic acid molecules and antisense molecules. | 2009-09-03 |
20090221808 | Process for the Preparation of Nucleic Acid Duplexes - The invention is a process for the preparation of at least one nucleic acid duplex by the steps of: (a) synthesizing a first single strand oligonucleotide to produce a crude solution of the first single strand oligonucleotide; (b) purifying the first single strand oligonucleotide from the crude solution by first liquid chromatography to produce a solution of purified first single strand oligonucleotide in a first liquid chromatography eluant; (c) synthesizing a second single strand oligonucleotide to produce a crude solution of the second single strand oligonucleotide; (d) purifying the second single strand oligonucleotide from the crude solution by second liquid chromatography to produce a solution of purified second single strand oligonucleotide in a second liquid chromatography eluant; (e) mixing the solution of purified first single strand oligonucleotide in the first liquid chromatography eluant with the solution of purified second single strand oligonucleotide in the second liquid chromatography eluant so that the first and second single strand oligonucleotides can complex to form a nucleic acid duplex in the mixture of first and second liquid chromatography eluants. | 2009-09-03 |
20090221809 | METHOD FOR THE SORPTION OF AT LEAST ONE NUCLEIC ACID-ACTIVATED PHYLLOSILICATES - The invention relates to a method for the sorption of at least one nucleic acid molecule from a liquid medium, comprising the following steps: (a) providing a liquid medium comprising at least one nucleic acid molecule; (b) providing a layer comprising at least one acid-activated phyllosilicate, where the layer is permeable by the liquid medium, and the layer thickness is at least 1 mm; (c) passing the liquid medium with the at least one nucleic acid molecule from step (a) through the layer from step (b) for sorption of the at least one nucleic acid molecule in the layer. | 2009-09-03 |
20090221810 | PROCESS FOR THE REMOVAL OF EXOCYCLIC BASE PROTECTING GROUPS - A process for removal of exocyclic nucleobase nitrogen-protecting groups from a protected oligonucleotide comprising at least one 2′-O-protected nucleotide or 2′-halo-, such as a 2′-fluoro-, nucleotide is provided. The process comprises contacting the protected oligonucleotide with a solution of an inorganic base selected from the group consisting of lithium hydroxide, lithium carbonate, sodium carbonate and potassium carbonate. | 2009-09-03 |
20090221811 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES - The present invention provides processes for preparing intermediates useful in the preparation of gemcitabine and other nucleosides, and processes for preparing gemcitabine therewith. Exemplary intermediates include mixtures of D-erythro and D-threo isomers of 3-(hydroxy)-2,2-difluoro-3-(2,2-dimethyldioxolan-4-yl)-propionic acid salts. Also provided is a process for selectively isolating the D-erythro and D-threo isomers of D-erythro and D-threo isomers of 3-(hydroxy)-2,2-difluoro-3-(2,2-dimethyldioxolan-4-yl)-propionic acid salts, and processes for using such isomers in the preparation of nucleoside analogs such as, e.g., gemcitabine, intermediates thereof, and analogs thereof. | 2009-09-03 |
20090221812 | METHOD FOR THE MANUFACTURE OF MICROFIBRILLATED CELLULOSE - A method for treatment of chemical pulp for the manufacturing of microfibrillated cellulose includes the following steps: a) providing a hemicellulose containing pulp, b) refining the pulp in at least one step and treating the pulp with one or more wood degrading enzymes at a relatively low enzyme dosage, and c) homogenizing the pulp thus providing the microfibrillated cellulose. According to a second aspect of the invention a microfibrillated cellulose obtainable by the method according to the first aspect is provided. According to a third aspect of the invention, use of the microfibrillated cellulose according to the second aspect in food products, paper products, composite materials, coatings or in rheology modifiers (e.g. drilling muds) is provided. | 2009-09-03 |
20090221813 | Homogeneous synthesis of cellulose ethers in ionic liquids - The invention is directed to a simple and new method for the homogeneous synthesis of cellulose ethers. Ionic liquids are not only used as solvent, but also as reaction media for the homogeneous etherification of cellulose. The dissolved cellulose is treated with the etherification agent in the absence of organic and/or inorganic bases and in the absence and/or in the presence of moderate amounts of water. The obtained cellulose ethers show new distributions of substitution on the polymer chain, resulting in new properties and applications. | 2009-09-03 |
20090221814 | SYSTEM AND METHOD FOR PREEXTRACTION OF HEMICELLULOSE THROUGH USING A CONTINUOUS PREHYDROLYSIS AND STEAM EXPLOSION PRETREATMENT PROCESS - A system has been developed for pretreating cellulosic biomass feed stock including: a first pressurized reactor receiving the feed stock, wherein the feed stock undergoes hydrolysis in the first pressurized reactor; a sealing device having a first pressurized coupling to a feedstock discharge port of the first pressurized reactor, and a second pressurized coupling to a second pressurized reactor; a drain for a liquid including dissolved hemi-cellulosic material extracted from the feed stock in at least one of the first pressurized reactor and the sealing and extraction device; the second pressurized reactor assembly receiving the pressurized feed stock from the sealing device at a pressure substantially greater than the pressure in the first pressurized reactor, wherein cells of the feed stock are infused with water in the second pressurized reactor, and an expansion device downstream of the second pressurized reactor assembly, wherein the expansion device rapidly releases the pressure of the feed stock discharged from the second pressurized reactor such that the feed stock undergoes a steam explosion reaction. | 2009-09-03 |
20090221815 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES - Provided is a process for preparing a compound of formula 1 or its salt, which includes reacting a compound of formula 2 with a compound of formula 3 in the presence of a base. | 2009-09-03 |
20090221816 | Process for the Asymmetric Epoxidation of Olefins - The present invention relates to a catalyst based on ruthenium complexes and to a process for the asymmetric epoxidation of olefins using catalysts based on ruthenium complexes. | 2009-09-03 |
20090221817 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXILIC ACID DERIVATIVES - A process for the preparation of Compound (I) comprising reacting Compound (II) with a base in an aprotic solvent, which is represented by the following scheme: | 2009-09-03 |
20090221818 | Inhibitors of Fibroblast Activation Protein Alpha - Disclosed are peptide-based compounds that include boronic acid or cyano functionality, which efficiently and selectively inhibit fibroblast activation protein alpha. Among other therapeutic utilities, the peptide-based compounds may be useful for the treatment of cancer. | 2009-09-03 |
20090221819 | FLUORESCENT COMPOUNDS AND USE OF SAID COMPOUNDS IN MULTIPHOTON METHODS OR DEVICES - The invention relates to a chemical compound with an effective double photon absorbance section of greater than 50 GM, preferably greater than 100 GM, for at least one wavelength in the range 700-1200 nm, characterised in being made up of a core with double photon absorption properties connected by separate covalent bonds to at least two boron dipyrromethene type emitters of formula (—BDP) (I): where one of R | 2009-09-03 |
20090221820 | Ligands for Transition-Metal-Catalyzed Cross-Couplings, and Methods of Use Thereof - Ligands for transition metals are disclosed herein, which may be used in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The disclosed methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition-metal-catalyzed cross-coupling reactions. | 2009-09-03 |
20090221821 | ADENOSINE RECEPTOR ANTAGONISTS AND METHODS OF MAKING AND USING THE SAME - The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A | 2009-09-03 |
20090221822 | Process for the Preparation of Dihydroquinazolines - The present invention relates to a process for the preparation of dihydroquinazolines, which are used for the production of medicaments. | 2009-09-03 |
20090221823 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES - The present invention is related to 1-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients. | 2009-09-03 |
20090221824 | ENANTIOSELECTIVE PROCESS - A process for the production of compounds comprising the enantioselective hydrogenation of 2-substituted acrylic acid derivatives. | 2009-09-03 |
20090221825 | Process for the Preparation of 3-Hydroxymorphinan Derivatives - Processes are described for the synthesis of 3-hydroxymorphinan derivatives by hydrolysis of side products from the O-demethylation of 3-methoxymorphinan derivatives. | 2009-09-03 |
20090221826 | Process for making topotecan - A process of making topotecan or a pharmaceutically acceptable salt thereof comprising reacting an iminium salt with 10-hydroxy-camptothecin. | 2009-09-03 |
20090221827 | PROCESSES FOR THE PREPARATION OF DIFFERENT FORMS OF (S)-(+)-CLOPIDOGREL BESYLATE - Disclosed herein are the improved processes for the preparation of different forms of (S)-(+)-Clopidogrel besylate, pharmaceutical compositions containing them and their use in medicine. | 2009-09-03 |
20090221828 | Process for Preparing 1-Halo-2,7-Naphthyridinyl Derivatives - A process for preparing 1-halo-2,7-naphthyridinyl derivatives is described (I), wherein X is Cl or Br; which process comprises the following steps: (i) reaction of a 3-cyano-4-methylpyridine derivative of formula (A): with a compound of formula (II), in the presence of an N,N-dimethylformamide diC | 2009-09-03 |
20090221829 | 3,4-Dihydroisoquinolinium Salt Derivatives - The present invention relates to 3,4-dihydroisoquinolinium salt derivatives. More specifically, the present invention relates to 3,4-dihydroisoquinolinium salt derivatives of the following chemical formula (I). | 2009-09-03 |
20090221830 | Fexofenadine Polymorphs and Processes of Preparing the Same - Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith. | 2009-09-03 |
20090221831 | Method for Producing N,N-Bis(Pyridin-2Ylmethyl)-1,1-Bis(Pyridin-2-Yl)-1-Aminoalkane Compounds and Metal Complex Salts Containing These Compounds - The invention relates to a method for producing the compositions cited in the title. According to this method: dipyridyl ketone is reacted with hydroxylamine; the oxime obtained thereby is reduced without intermediate isolation to form 1,1-di-(2-pyridyl)-methylamine, and; this amine is firstly reacted with 1 to 1.5 molar equivalent of picolyl chloride and then with another 1 to 1.5 molar equivalent of picolyl chloride to form the amine of formula (1). | 2009-09-03 |
20090221832 | PROCESS FOR PREPARING KETONES FROM ALPHA-OXO CARBOXYLATES AND ARYL BROMIDES - A process for preparing ketones of the general formula (III) | 2009-09-03 |
20090221833 | Polymorphic Form of Lercanidipine Hydrochloride and Process for the Preparation Thereof - Processes for the purification of lercanidipine hydrochloride are provided which uses a binary system of an alcohol-containing solvent such as methanol and an aliphatic ester-containing solvent such as isopropyl acetate. Processes for the preparation of substantially amorphous lercanidipine hydrochloride are also provided. Also provided is lercanidipine hydrochloride substantially in polymorph form V. | 2009-09-03 |
20090221834 | Synthesis of 5-Beta-Keto-1,2,4-Oxadiazoles and Conversion of 5-Beta-Keto-1,2,4 Oxadiazoles to N-Pyrazolyl Amidoximes - The disclosed invention relates to a process for preparing 5-β-keto-1,2,4-oxadiazoles of formula (I), and conversion of 5-β-keto-1,2,4-oxadiazoles (I) into N-pyrazolyl amidoximes of the formula (II) through reaction with hydrazine. The process is defined by two steps. An amidoxime, which may be prepared in situ, is condensed with a β-keto ester to form a 5-β-keto-1,2,4-oxadiazole. The 5-β-keto-1,2,4-oxadiazole is subsequently reacted with hydrazine to furnish the desired N-pyrazolyl amidoxime. The disclosed invention provides several advantages over the current state of the art for the synthesis of N-pyrazolyl amidoximes, which require the condensation of a pyrzolylamine with an actived substrate and subsequent reaction with hydroxyl amine. N-pyrazolyl amidoximes are useful synthetic intermediates, especially for the preparation of photographic developing chemicals. | 2009-09-03 |
20090221835 | PROCESSES FOR PREPARING BIARYL UREAS AND ANALOGS THEREOF - The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for preparing compounds that inhibit IMPDH. | 2009-09-03 |
20090221836 | PROCESS FOR THE PREPARATION OF VALSARTAN AND PRECURSORS THEREOF - This invention relates to a process for preparing intermediates useful in preparing Valsartan and to a process for preparing the latter, together with synthesis intermediates of formula (IV), (V) and (VI), useful for manufacturing a medicament for the treatment of arterial hypertension or heart failure. The process for preparing Valsartan permits it to be prepared on an industrial scale with high yields and without racemisation problems, in addition to using simple and available starting products. The invention also provides a process for preparing the intermediate of formula (VI), from an intermediate of formula (V) that does not require protection of the carboxylic acid prior to N-acylation. | 2009-09-03 |
20090221837 | Process for the Preparation of Pure Anastrozole - The present invention relates to the improved process for the preparation of Anastrozole free from the impurities arising due to impure 3,5-bis-(1-cyano-1-methylethyl)benzylbromide (2) and other related impurities resulting from incomplete/over-reaction of 2,2-(5-methyl-1,3-phenylene)-bis(2-methylpropionitrile (I). | 2009-09-03 |
20090221838 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRAZOLES - The invention relates to an alternative process for the preparation of substituted 5-amino-pyrazoles, in which a carbonyl compound is reacted with a hydrazine derivative and cyanogen chloride to give an N-cyanohydrazone which is cyclized in the presence of a strong base. | 2009-09-03 |
20090221839 | Preparation of an Atorvastatin Intermediate - Atorvastatin lactone is prepared by hydrogenating tert-butyl isopropylidene nitrile to tert-butyl isopropylidene amine and condensing the amine with the diketone of atorvastatin to form acetonide ester. The diol protecting acetonide ester is deprotected to form a diol ester by dissolving the acetonide ester in methanol and treating with an acid. The diol ester is saponified to form a sodium salt. Methanol is removed from the reaction mixture by distillation. The sodium salt is reacidified to the free diol acid and atorvastatin lactone is formed from the diol acid. The atorvastatin lactone is directly dried without further purification. | 2009-09-03 |
20090221840 | PROCESS FOR PURIFYING ETHYLENE CARBONATE, PROCESS FOR PRODUCING PURIFIED ETHYLENE CARBONATE, AND ETHYLENE CARBONATE - Ethylene carbonate having a highly reduced content of especially diols is provided. | 2009-09-03 |
20090221841 | 2-SUBSTITUTED ESTRA-1,3,5(10)-TRIENE-3-YL SULFAMATE WITH AN ANTI-TUMOUR ACTION - The invention relates to the use of 2-substituted estra-1,3,5(10)-triene-3-yl sulfamates of general formula I, in addition to their pharmaceutically acceptable salts for producing a medicament. Said compounds have an anti-tumour action. | 2009-09-03 |
20090221842 | METHOD FOR THE PRODUCTION OF ORGANOSILICON COMPOUNDS COMPRISING CARBOXY RADICALS - Organosilicon compounds bearing carboxylic acid groups are easily and economically replaced in high yield by oxidation of a carbinol-functional organosilicon compound with an oxidizer in the presence of a moderator at a pH≧3. Carboxyl-functional organopolysiloxanes highly useful as textile softeners may be obtained by this method. | 2009-09-03 |
20090221843 | CATALYST FOR PRODUCING ACRYLONITRILE AND PROCESS FOR PRODUCING ACRYLONITRILE - A catalyst for producing acrylonitrile capable of maintaining a high yield of acrylonitrile for a long time is provided. The catalyst has a composition represented by Mo | 2009-09-03 |
20090221844 | Guanidine-substituted resin for transesterification - A polymeric resin comprising guanidine groups having at least one C | 2009-09-03 |
20090221845 | FLUORINATED COMPOUND, AND FLUOROPOLYMER, PROCESS FOR ITS PRODUCTION AND RESIST COMPOSITION CONTAINING IT - To provide a fluoropolymer having functional groups and having high transparency in a wide wavelength region, and a resist composition comprising the fluoropolymer. | 2009-09-03 |