32nd week of 2009 patent applcation highlights part 43 |
Patent application number | Title | Published |
20090197762 | Solid catalyst component for olefin polymerization, catalyst for olefin polymerization and process for producing olefin polymer - A solid catalyst component for olefin polymerization in which the molar ratio of residual alkoxy groups to supported titanium is 0.60 or less is obtained by reacting the following compound (a1) with the following compound (b1) at a hydroxyl group/magnesium molar ratio of 1.0 or more, reacting the reaction mixture with the following compound (c1) at a halogen/magnesium molar ratio of 0.20 or more, reacting the resultant reaction mixture with the following compounds (d1) and (e) at a temperature of 120° C. or higher but 150° C. or lower, washing the reaction mixture with an inert solvent, reacting the reaction mixture with the following compound (e) again at the above temperature and washing the reaction mixture with an inert solvent, whereby there can be provided the solid catalyst component for olefin polymerization and a catalyst for olefin polymerization which have high polymerization activity and give an olefin polymer having a less residual Cl content and being excellent in stereoregularity and powder form and a process for producing an olefin polymer,
| 2009-08-06 |
20090197763 | Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method - Provided is a decomposition method of an aromatic block copolymer, wherein the aromatic block copolymer comprises a segment 1 represented by the following general formula (1) and a segment 2 comprising a structural unit represented by the following general formula (2) and/or a structural unit represented by the following general formula (3), and the segment 2 is subjected to chemical decomposition. | 2009-08-06 |
20090197764 | CATALYST FOR PURIFYING EXHAUST GAS - In the present invention, it is an assignment to optimize a loading density of noble metal on catalyst. | 2009-08-06 |
20090197765 | SOLID FORMULATION OF LOW MELTING ACTIVE COMPOUND - The present invention is directed to solid formulations comprising a low melting active compound. The solid formulations particularly can comprise pesticidal low melting compound, including herbicides, such as fluroxypyr and derivatives thereof. The invention further provides methods of preparing the formulations and methods of plant treatment using the solid formulations. | 2009-08-06 |
20090197766 | Organic Herbicide and Method For Manufacturing - An organic agent for controlling weeds (a so-called herbicide) primarily includes ingredients which are used for human nutrition and the individual components are harmless to nature (including animals and people). These ingredients include extract of garlic, cayenne pepper, nettles and sugar in the form of dextrose. Thorough tests have documented that the new organic herbicide has the same efficiency or is better than one of the hitherto most-used chemical herbicides. | 2009-08-06 |
20090197767 | PYRIDINE KETONES WITH HERBICIDAL EFFECT - The invention relates to compounds of formula (I) wherein A | 2009-08-06 |
20090197768 | STABILIZED OIL-IN-WATER EMULSIONS INCLUDING AGRICULTURALLY ACTIVE INGREDIENTS - The present invention relates to stable, agricultural oil-in-water emulsion compositions. | 2009-08-06 |
20090197769 | Electric power feed structure for superconducting apparatus - An electric power feed structure for a superconducting apparatus, which is used to input or output electric power between the cryogenic-temperature side and the room-temperature side, comprises a coolant vessel containing a superconducting section provided in the superconducting apparatus, a vacuum thermal insulation vessel arranged to surround the outer periphery of the coolant vessel, and a feed conductor part having one end arranged in the room temperature side and having the other end connected to the superconducting section. The feed conductor part is divided into a cryogenic-temperature side conductor connected to the superconducting section and a room-temperature side conductor arranged in the room temperature side such that the cryogenic-temperature side conductor and the room-temperature side conductor can be detachably attached to each other. Thus, provided are the electric power feed structure for a superconducting apparatus and a superconducting cable line equipped with the electric power feed structure in which the electric power fed between the cryogenic-temperature side and the room-temperature side can be easily varied by changing an effective conductor cross-sectional area. | 2009-08-06 |
20090197770 | BISMUTH BASED OXIDE SUPERCONDUCTOR THIN FILMS AND METHOD OF MANUFACTURING THE SAME - A Bi-based oxide superconductor thin film whose c-axis is oriented parallel to the substrate and whose a-axis (or b-axis) is oriented perpendicular to the substrate, is manufactured in order to obtain a high performance layered Josephson junction using a Bi-based oxide superconductor. The method of manufacturing an a-axis oriented Bi-based oxide superconductor thin film, involves an epitaxial growth process using an LaSrAlO | 2009-08-06 |
20090197771 | METHOD OF MANUFACTURING OXIDE SUPERCONDUCTING WIRE, METHOD OF MODIFYING OXIDE SUPERCONDUCTING WIRE AND OXIDE SUPERCONDUCTING WIRE - A method of manufacturing an oxide superconducting wire according to the present invention comprises a step (S | 2009-08-06 |
20090197772 | Compartmentalised combinatorial chemistry by microfluidic control - The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules. | 2009-08-06 |
20090197773 | Bioreaction Execution System and Bioreaction Execution Method, DNA Chip, Information Processing System and Information Processing Method, Program, and Recording Medium - This invention relates to a bioreaction execution system and bioreaction execution method capable of producing electric fields in a flow channel, into which a solution with a target gene contained therein is dropped, on a DNA chip and causing the target gene to electrophoretically migrate, the DNA chip, an information processing system and information processing method, a program, and a recording medium. An AC supply unit | 2009-08-06 |
20090197774 | METHOD FOR DIAGNOSING THROMBOEMBOLIC DISORDERS AND CORONARY HEART DISEASE - The present invention refers to a method for the in vitro diagnosis of thromboembolic and/or coronary heart diseases, wherein the nucleotide at position 470 of a nucleic acid coding for the human EGLN2 protein or the amino acid at position 58 of the human EGLN2 protein of a sample of a person is determined. | 2009-08-06 |
20090197775 | NUCLEASE ON CHIP - The present invention pertains to a method for determining point mutations on micro-arrays/biochips using a nuclease capable to selectively digest hybridized DNA strands into two DNA fragments, said hybridized DNA strands containing a nucleotide mismatch or nucleotide deletion. The occurrence and/or location of such DNA fragments are indicative for a point mutation. | 2009-08-06 |
20090197776 | Liquid Tissue Preparation From Histopathologically Processed Biological Samples, Tissues and Cells - The current invention provides a method for directly converting histopathologically processed biological samples, tissues, and cells into a multi-use biomolecule lysate. This method allows for simultaneous extraction, isolation, solublization, and storage of all biomolecules contained within the histopathologically processed biological sample, thereby forming a representative library of said sample. This multi-use biomolecule lysate is dilutable, soluble, capable of being fractionated, and used in any number of subsequent experiments. | 2009-08-06 |
20090197777 | METHOD OF MAKING AND USING MICROARRAYS SUITABLE FOR HIGH THROUGHPUT DETECTION - Disclosed are high density microarrays and methods for making and using such microarrays. The microarrays of the present invention can have uniformly shaped and sized sensing zones and are designed to allow high-throughput detection assays with minimal noise. | 2009-08-06 |
20090197778 | Heated Reaction Chamber For Processing A Biochip And Method For Controlling Said Reaction Chamber - The invention relates to a heated reaction chamber for processing a biochip and to a method for controlling said reaction chamber. The heated reaction chamber for processing a biochip comprises a chamber wall, constituted by a flexible circuit board ( | 2009-08-06 |
20090197779 | METHOD FOR ENHANCED RECOVERY OF OIL FROM OIL RESERVOIRS - The present invention provides a method for recovering oil from a subterranean reservoir using waterflooding, wherein the flooding fluid used in the waterflooding process comprises water and one or more of 1,3-propanediol, oligomers of 1,3-propanediol and polymers of 1,3-propanediol. The use of 1,3-propanediol, oligomers and/or polymers thereof is expected to increase the recovery of oil by improving both the oil/water mobility ratio and the sweep efficiency in reservoirs with a high degree of heterogeneity. | 2009-08-06 |
20090197780 | Ultrafine Grinding of Soft Materials - Compositions and methods pertaining to the ultrafine grinding of soft materials are disclosed. In one embodiment, a method comprises the step of mixing a soft material with an additive to form a mixture. The method further comprises raising the temperature of the mixture to at least the glass transition temperature of the soft material. The method further comprises cooling the temperature of the mixture. The method further comprises grinding the mixture to form ultrafine particles that comprise at least a portion of the soft material. | 2009-08-06 |
20090197781 | Wellbore Fluids Comprising Poly(trimethylene ether) glycol Polymers - Wellbore fluids containing poly(trimethylene ether)glycols are provided. The wellbore fluids can provide enhanced functionality, improved cost effectiveness, and reduced environmental impact as compared to conventional wellbore fluids. | 2009-08-06 |
20090197782 | SOFT MAGNETIC MATERIAL AND DUST CORE - A soft magnetic material includes a plurality of composite magnetic particles including a metal magnetic particle and an insulating film surrounding a surface of the metal magnetic particle. The insulating film also contains a phosphate. The soft magnetic material further includes an aromatic polyetherketone resin and a metallic soap and/or an inorganic lubricant having a hexagonal crystal structure. The metallic soap and the inorganic lubricant are particles with an average particle size of not more than 2.0 μm. | 2009-08-06 |
20090197783 | Engine oil compostions - A lubricating oil composition comprising (a) a major amount of a base oil of lubricating viscosity and (b) a minor deposit-inhibiting effective amount of a reaction product prepared by transesterifying at least one glycerol ester and at least one non-glycerol polyol ester is provided. Methods for its use are also provided. | 2009-08-06 |
20090197784 | Shampoo Compositions Containing a Combination of Cationic Polymers - The invention provides an aqueous shampoo composition comprising: (i) one or more anionic cleansing surfactants; (ii) preferably, discrete, dispersed droplets of a water-insoluble conditioning agent with a mean droplet diameter (D | 2009-08-06 |
20090197785 | STRUCTURED CLEANING COMPOSITIONS - A stable, pourable or pasty, homogeneous exfoliant composition having particulate, solid sugar suspended in a saturated aqueous solution of said sugar, and sufficient surfactant to form, in conjunction with said solution, a stable, solid-supporting structured surfactant system. | 2009-08-06 |
20090197786 | Hard Surface Cleaning Compositions - The present invention relates to hard surface cleaning compositions useful in cleaning, and optionally a disinfecting or sanitizing benefit which are particularly adapted to clean lavatory appliances, particularly toilets and the like. The compositions are largely aqueous, thickened, acidic compositions which comprise an acid, a thickening constituent or constituents which form a thickener system, at least one detersive surfactant and at least one superwetter surfactant which is based on a narrow range ethoxylated alcohol nonionic surfactant having two cloud points. | 2009-08-06 |
20090197787 | Multilayer Detergent Tablet - The invention relates to a detergent tablet characterized in that it comprises five layers superimposed on each other, with at least three layers among the five layers having different compositions. The invention also relates to a method for manufacturing such a detergent tablet. | 2009-08-06 |
20090197788 | RezOlex curling iron clean - A non-caustic chemical composition for cleaning surfaces of heat encrusted curling irons, clothes irons of metal, ceramic stovetops, fiberglass bath tubs, shower, sinks, boats, resin furniture, porcelain, and plastic is provided in the form of foam, and liquid sprays. A chemical composition consist of three active ingreadieances 12% diethylene glycol monobutyl ether and sodium carbonate and/or potassium carbonate anhydrous 7%, potassium carbonate preferred, in an aerosol cleaner formulation of monoethanolamine 5%, and Isobutane 5% comprises chemical composition to be applied to said surfaces in aqueous solution. A chemical composition consisting in the form of foam cleaner is much more preferred over scraping curling irons with razor blades, steel wool, comet, alcohol, and trying to soak in water, which runs the irons. The cleaning composition in the form of liquid in a trigger sprays, works well on flat surfaces. A chemical composition in the form of aerosol spray can with pressurized valves sprays a fine mist of foam, which adheres to vertical walls, curved surfaces, allowing cleaner to remain on surface for a period of time, shake, spray, wait, wipe with clean water, with the time period of 10 minutes to 2 hours makes cleaning time more time efficient. | 2009-08-06 |
20090197789 | ACETYLATION OF CHITOSAN - A process for making modified N-acetylated chitosan comprising the steps of:
| 2009-08-06 |
20090197790 | Drip resistant cleaning compositions - The present disclosure is directed to both sprayable and non-sprayable cleaner compositions comprising 1 to 9% by weight of a layered phyllosilicate, 1 to 10% of a surfactant, and at least one silicate salt or strong base as a pH-adjusting agent. The composition optionally can include hypochlorite bleach and the pH of the formulation can be in the range 11 to 14. The composition optionally can include water-insoluble glycol ether type solvents or oils in the form of emulsions or microemulsions for degreasing, disinfecting, and fragrance delivery. The compositions provide improved drip resistance when sprayed on to vertical surfaces. | 2009-08-06 |
20090197791 | COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE - The present invention provides a new copolymer comprising zwitterionic units and other units, a new composition comprising the copolymer, and the use of the copolymer or the compositions for treating or modifying surfaces. | 2009-08-06 |
20090197792 | Drip resistant acidic compositions for sprayable and non-sprayable application - The present disclosure is directed to acidic cleaning compositions comprising 1 to 9% by weight of a layered phyllosilicate in surface modified sodium or protonated forms and pre-dispersed in pre-gel form with and without additives, 1 to 5% of an anionic surfactant, 2-10% of a hydrotope, 0.1-15% solvents, and at least one organic or inorganic acid as a pH-adjusting agent to provide a composition having a pH less than about 4.0. The compositions provide improved viscosity profile, sprayability, and drip resistance when applied to vertical surfaces. | 2009-08-06 |
20090197793 | DETERGENT COMPOSITION FOR HARD SURFACE - Disclosed is a detergent composition for hard surface, containing (A) a monoalkyl glyceryl ether whose alkyl group has 3 to 8 carbon atoms, (B) a specific compound represented by the formula (1), (C) an amine, (D) a polyvalent carboxylic acid having a molecular weight of 40 to 400 and/or a salt thereof, (E) a surfactant provided that (A) and (B) are excluded from (E), and water, wherein the mass ratio of (A)/(B), the content of (A)+(B), the mass ratio of (C)/(D), and the content of (C)+(D) are respectively in a specific range, and the pH of the detergent composition at 20° C. is 9.5 to 11.5. | 2009-08-06 |
20090197794 | Methods of Diagnosing and Treating an Inflammatory Response - The present invention relates to the discovery that VEGF, PlGF, and sFlt-1 levels are increased in inflammatory response such as in sepsis, severe sepsis, or septic shock. Additionally, the invention provides methods of identifying treatments as well as providing treatments for such an inflammatory response, which include decreasing VEGF or PlGF levels, or increasing sFlt- | 2009-08-06 |
20090197795 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY - This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases. | 2009-08-06 |
20090197796 | Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors - Methods are provided for treating HPG axis-positive cancers, preventing or slowing proliferation of cells of HPG axis-positive cancer origin, preventing HPG axis-positive cancers in a patient at risk of contracting such cancers, preventing or inhibiting an upregulation of the cell cycle in HPG axis-positive cancer-derived cells in a patient, and decreasing the level of HPG axis-positive cancer-specific markers in a patient. | 2009-08-06 |
20090197797 | USE OF HYALURONIC ACID AS A CARRIER MOLECULE FOR DIFFERENT CLASSES OF THERAPEUTIC ACTIVE AGENTS - The present invention refers to a drug delivery system consisting of hyaluronic acid and a therapeutic active agent. | 2009-08-06 |
20090197798 | COMPOSITION FOR TREATING CANCER AND USE THEREOF - The present invention provides a cyclic peptide containing RRXR motif. The present invention also provides a composition comprising the said cyclic peptide and a pharmaceutical acceptable carrier. The present invention further provides a method for treating cancer. | 2009-08-06 |
20090197799 | METHODS FOR PREPARING PURIFIED LIPOTIDES - The present invention relates to crystalline and crystal-like forms of lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention relates to methods of purifying lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention also relates to pharmaceutical compositions comprising the purified form of the lipopeptide and methods of using these compositions. | 2009-08-06 |
20090197800 | Insulin Receptor Binding Peptides with Non-Insulin Gene Activation Profiles and Uses Thereof - Methods for binding insulin receptors (and typically activating one or more function of an insulin receptor) by contacting insulin receptor-presenting cells, such as cells in a subject, with an effective amount of one or more insulin receptor binding peptides, where upregulation of one or more components of the insulin receptor-associated cholesterol synthesis pathway is not desired, are provided. | 2009-08-06 |
20090197801 | NEURITOGENIC PEPTIDES - The present invention relates to peptide compounds that are capable of stimulating neuronal differentiation, neurite outgrowth and survival of neural cells, and enhancing synaptic plasticity, learning and memory, methods of treating diseases and conditions of nervous system by administration of compositions comprising said compounds. The compounds and compositions of the invention include peptide sequences that are derived from the sequence of human erythropoietin or proteins that are homologous of human erythropoietin. | 2009-08-06 |
20090197802 | Analogues of GLP-1 - The present invention is directed to peptide analogues of glucagon-like peptide-1, the pharmaceutically-acceptable salts thereof, to methods of using such analogues to treat mammals and to pharmaceutical compositions useful therefor comprising said analogues. | 2009-08-06 |
20090197803 | METHODS AND COMPOSITIONS FOR MODULATING T HELPER (Th) CELL DEVELOPMENT AND FUNCTION - Methods and compositions for modulating T helper (Th) cell development and function using modulators of IL-21, e.g., human IL-21, activity or level. | 2009-08-06 |
20090197804 | Methods and Compositions for the Prevention and Treatment of Kidney Disease - Compositions for preventing or treating kidney disease comprising one or more food ingredients containing relatively low amounts of protein, sodium, and potassium, typically protein in amounts of from about 5% to about 40%, sodium in amounts of from about 0.01% to about 1%, and potassium in amounts of from about 0.01% to about 1%, and methods comprising administering such compositions to patients susceptible to or suffering from kidney disease for the purpose of preventing or treating kidney disease. | 2009-08-06 |
20090197805 | Insulin receptor antagonists and related compositions, uses and methods - Provided are new peptidic insulin receptor antagonists (PIRAs) and related compounds and compositions. Also provided are new uses of PIRAs and methods of obtaining PIRAs. | 2009-08-06 |
20090197806 | ADIPONECTIN FOR TREATMENT OF VARIOUS DISORDERS - Methods for treating various disorders by orally administering adiponectin or a biologically active fragment thereof are described. | 2009-08-06 |
20090197807 | SULPHATED HYALURONIC ACID FOR TREATING DEGENERATIVE OSTEOARTHRITIS - This invention relates to oral and intra-articular formulations based on sulphated hyaluronic acid which are effective in the treatment of degenerative osteoarthritis. | 2009-08-06 |
20090197808 | METHODS AND COMPOSITIONS FOR THE REDUCTION OF NEUTROPHIL INFLUX AND FOR THE TREATMENT OF BRONCHPULMONARY DYSPLASIA, RESPIRATORY DISTRESS SYNDROME, CHRONIC LUNG DISEASE, PULMONARY FIBROSIS, ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of Respiratory Distress Syndrome (RDS), Bronchopulmonary dysplasia (BPD), chronic lung disease and/or pulmonary fibrosis, Asthma and Chronic Obstructive Pulmonary Disease (COPD). More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 2009-08-06 |
20090197809 | ANTIFUNGAL METHODS - A system for reducing the incidence or severity of fungal infection of a plant, comprising a chemical fungicide component, which may be provided by foliar or root (soil or liquid nutrient) application, together with an antifungal plant defensin not in nature expressed in the plant being protected or expressed in lower amounts or in different tissues, provides synergistic improvement in protection against infection by a plant pathogenic fungus which is susceptible to the defensin and the fungicide. The fungicide can be a strobilurin or a triazole, and the defensin can be selected from a wide range of known defensins, for example, NaD1 and others, or it can be a chimeric defensin engineered for low toxicity to the plant. The defensin can be provided as a protein formulation, optionally together with the fungicide, or it can be provided by recombinant expression in the plant to be protected from fungal infection. | 2009-08-06 |
20090197810 | ALPHA CONOTOXIN PEPTIDES WITH ANALGESIC PROPERTIES - This invention relates to novel α-conotoxin-like peptides comprising the following amino acid sequence (SEQ ID NO: | 2009-08-06 |
20090197811 | ORALLY ADMINISTERED PEPTIDES TO IMPROVE OR PREVENT HEPATIC FIBROSIS - The present invention generally relates to liver disease. More specifically the invention provides compositions and methods, including D-4F, that are useful in treating or preventing hepatic fibrosis. | 2009-08-06 |
20090197812 | Peptides for Inhibiting Transglutaminase - Disclosed herein are transglutaminase peptide inhibitors which have inhibitory activity against transglutaminase, and a pharmaceutical composition comprising one of them as an active ingredient. The inhibitors or the composition is useful in the prevention and treatment of various diseases caused by aberrant transglutaminase activation, including inflammatory diseases and cancers. Also, methods for treating various inflammatory diseases and cancers and for preparing mutant peptides capable of inhibiting transglutaminase are also disclosed. | 2009-08-06 |
20090197813 | Methods for treating FSH related conditions with GnRH antagonists - Methods for treating FSH related conditions, such as prostatic intraepithelial neoplasia, pedophilia, infertility, or vaginal bleeding, with GnRH antagonists are disclosed. The methods of the invention generally feature administering to a subject a GnRH antagonist suitable for in vivo administration and able to reduce both plasma FSH and LH levels in a subject, in an amount or in a formulation effective to reduce plasma FSH levels in the subject to a symptom alleviating level. In vitro fertilization and male contraceptive methods are also provided. | 2009-08-06 |
20090197814 | Method of inhibiting the emigration of cells from the intravascular compartment into tissues - A method of inhibiting the emigration of cells from the intravascular compartment into tissues (or through any membrane limiting any body compartment from another) by confronting the cells with an agonist specific for receptors involved with migration of said cells via a receptor thereby making the cell unresponsive to further activation. | 2009-08-06 |
20090197815 | COMBINATION OF SOMATOSTATIN-ANALOGS WITH DOPAMINE- OR GROWTH HORMONE RECEPTOR ANTAGONIST - The present invention concerns a product containing Sandostatin® LAR® at 40 mg/28 days or pasireotide and either a dopamine-agonist, preferably cabergoline, or a growth hormone receptor antagonist, preferably pegvisomant, as a combined preparation for simultaneous, separate or sequential use in acromegalic therapy. In particular, this therapy is useful for treating acromegalic patients not achieving biochemical normalization after at least six-month treatment using at least one somatostatin analogue at conventional regimen. | 2009-08-06 |
20090197816 | Stabilizing Alkylglycoside Compositions and Methods Thereof - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example amylin, a monoclonal antibody, insulin, Peptide T or analog thereof, gastrin, gastrir releasing peptides, gastrin releasing peptide-like (GRP) proteins, epidermal growth factor or analog thereof. | 2009-08-06 |
20090197817 | Tetrahdrofuro[3,2-B] pyrrol-3- one as cathepsin k inhibitors - The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, | 2009-08-06 |
20090197818 | Use Of Ribose for Recovery From Anaesthesia - D-Ribose is administered before and after general anaesthesia to reduce the time to recover from the effects of general anaesthesia. Preferably, pyrogen-free D-Ribose is administered intravenously during general anaesthesia and the interval post-anaesthesia before oral administration can be resumed. D-Glucose may be co-administered to reduce the effect of hypoglycemia that may be seen with D-Ribose administration. | 2009-08-06 |
20090197819 | Compositions for improving and repairing skin - Compositions for improving the condition of the skin or for repairing damaged skin are disclosed. The compositions contain D-ribose as the active ingredient plus a penetrant to deliver D-ribose to the basal cells and dermis of the skin. Compositions further containing emollients and emulsifiers are disclosed. | 2009-08-06 |
20090197820 | Compositions and Methods for Improving Cardiovascular Health - Compositions and methods for improving cardiovascular health in the elderly by delivering a selection of essential amino acids, phytosterols, stanols, and isoflavones, which may be supplemented with a low glycemic carbohydrate and/or a medium chain fatty acid. | 2009-08-06 |
20090197821 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF POORLY WATER SOLUBLE DRUGS AND METHODS OF TREATMENT - The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water-soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions | 2009-08-06 |
20090197822 | Compositions and Methods for the Treatment of Chronic Infections - The present disclosure provides compositions and methods for the treatment and elimination of chronic intracellular infections in cells or organisms. The compositions may include one or more acidic substances and one or more antimicrobial substances, administered in combination or separately. The methods may include administering an amount of one or more such compositions to an infected cell or organism for a period of time ranging from days to years, until the infection is substantially eliminated. | 2009-08-06 |
20090197823 | ALISKIREN MODULATION OF NEUROGENESIS - The disclosure provides compositions and methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis by use of a renin inhibitor in combination with one or more neurogenic agents. The disclosure also includes compositions and methods for stimulating or activating the formation of new nerve cells based on the application of a renin inhibitor in combination with one or more neurogenic agents. | 2009-08-06 |
20090197824 | Extended Release Pharmaceutical Formulations of S-Adenosylmethionine - Extended release formulations of S-methyladenosylmethionine (SAMe) are provided, as are methods of treating various disorders using extended release SAMe formulations. The extended release formulations may be used to treat a variety of disorders, including liver disorders, psychiatric disorders and joint disorders. Thus, extended release SAMe formulations may be used to treat alcoholic liver disease, fatty liver disease, hepatitis, generalized anxiety disorder, obsessive compulsive disorder, post traumatic stress disorder, panic disorder, and depressive disorders such as depression (e.g. major clinical depression) and dysthymia. | 2009-08-06 |
20090197825 | NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE - Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid. | 2009-08-06 |
20090197826 | P-Toluene Sulfonic Acid Salt of 5-Amino-3-(2'-O-Acetyl-3'-Deoxy-Beta-D-Ribofuranosyl)-3H-Thiazole[4,5-d]p- yrimidine-2-one and Methods for Preparation - The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer. | 2009-08-06 |
20090197827 | Combination Therapy for Treatment of FIV Infection - The present invention pertains to methods for therapeutic and prophylactic treatment of cats against FIV infection. Methods of the present invention utilize a combination of antiretroviral compounds to treat or prevent FIV infection in a feline animal. In one embodiment, the method comprises administering an effective amount of AZT and another nucleoside analog, such as, for example, 3TC to the animal. In another embodiment, cats are given an effective dose(s) of AZT, 3TC, and a retroviral protease inhibitor. | 2009-08-06 |
20090197828 | SYSTEM, METHOD AND PACKAGE FOR PROVIDING A SUCROSE SOLUTION - A solution of sucrose and water is packaged and placed in an aseptic state in a cup-shaped container with a removable cover for single patient use. A plurality of containers is shipped from a preparation site to a site of usage such as a hospital. A single container of the solution is opened at a site of a procedure for a neonatal infant, and the solution administered prior to the procedure as well as during or afterward, as needed for analgesic effect. Any residual solution is discarded after the procedure to prevent cross contamination of other patients. | 2009-08-06 |
20090197829 | Crosslinked polysaccharides and methods of production thereof - A substantially boron-free method for making a cationic guar comprises reacting particles of polysaccharide with a derivatizing agent to produce derivatized polysaccharide particles, washing the derivatized polysaccharide particles, and contacting, prior to or after the washing step, the particles with a glyoxal compound in order to crosslink the derivatized polysaccharide particles. Also disclosed are methods for making crosslinked derivatized polysaccharides, comprising (a) contacting particles of a polysaccharide with a titanium compound in an aqueous medium having an alkaline pH under conditions appropriate to intra-particulately crosslink the particles; (b) reacting, prior to or after the step of contacting the particles of polysaccharide with the titanium compound, the particles of polysaccharide with a derivatizing agent under conditions appropriate to produce derivatized polysaccharide particles; (c) washing the titanium crosslinked and derivatized particles; (d) contacting, concurrently with or after the step of washing the titanium crosslinked and derivatized particles, such particles with an aqueous medium having an acidic pH under conditions appropriate to substantially de-crosslink the particles; and (e) contacting, concurrently with or after step (d), the de-crosslinked particles with a glyoxal compound under conditions appropriate to intra-particulately crosslink the particles. The crosslinked cationic guar of the present invention is especially useful in home and personal care formulations, especially formulations comprising silicone since it improves silicone deposition. | 2009-08-06 |
20090197830 | Combination of polychitosamine and hmg-coa reductase inhibitor for hyperlipidemia - Combinations of therapeutic compounds for prophylaxis or treatment of hyperlipidemia and hyperlipidemia related disorders, such as hypercholesterolemia and the resultant atherosclerosis in a mammal. The combinations are useful for reducing serum cholesterol, and/or cholesteryl ester, triglycerides, phospholipids and fatty acids in a mammal. The methods of the preferred embodiments comprise administering to a mammal a first amount of polychitosamine and a second amount of an HMG-CoA reductase inhibitor (statin). | 2009-08-06 |
20090197831 | Composition for the Treatment of Obesity and Hyperlipidemia - Current invention is related to the pharmaceutical industry in general and to the industry of the manufacture of pharmaceutical products for weight reduction and hyperlipidemia treatment. The advantages of the current invention respect of the similar of the state of the art are that in the present invention side effects normally produced by the consumption of lipase inhibitors are eliminated; optimizing both the lipase inhibitor component and the fat-trapping; with the adequate composition of each one of the components and with very small amounts of each one. The invention consists of a composition for the treatment of the obesity and hyperlipidemia, characterized by comprising in combination a lipase inhibitor and a fat-trapping component. | 2009-08-06 |
20090197832 | POLYMER MIXTURES OF ANIONIC AND CATIONIC POLYSACCHARIDES AND USE THEREOF - Described in the present application are compositions comprising mixtures of polyanionic polysaccharides and polycationic polysaccharides consisting of oligosaccharide derivatives of chitosan. In the compositions of the invention said mixtures have proven to be soluble in aqueous environments, despite ionic complexes forming between the acid polysaccharides and chitosan derivatives. Said compositions have also demonstrated significant rheological behaviour with an unexpected increase in viscosity and viscoelasticity, although the polysaccharides used have relatively low average molecular weights. The said solubility and rheological behaviour renders the compositions of the invention particularly advantageous from the biomedical application viewpoint, in particular for viscosupplementation and particularly in the field of articular pathologies and of ophthalmic surgery. | 2009-08-06 |
20090197833 | Silicon Containing Compounds Having Selective Cox-2 Inhibitory Activity and Methods of Making and Using the Same - Silicon-containing compounds having selective COX-2 inhibitory activity, as well as compositions thereof are provided. The subject compounds find use in a variety of applications, including therapeutic applications. Also provided are kits containing the subject compounds and pharmaceutical preparations thereof. | 2009-08-06 |
20090197834 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF - [Problem] To provide a compound having excellent platelet aggregation inhibitory activity. | 2009-08-06 |
20090197835 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS - The present invention provides LPA analogs that are antagonists at the LPA receptors. | 2009-08-06 |
20090197836 | Combination of FBPase Inhibitors and Antidiabetic Agents Useful for the Treatment of Diabetes - A combination therapy of at least one FBPase inhibitor and at least one other antidiabetic agent is disclosed. | 2009-08-06 |
20090197837 | ALENDRONATE FORMULATIONS, METHOD OF MAKING AND METHOD OF USE THEREOF - Disclosed is a liquid, oral dosage form comprising alendronic acid or pharmaceutically acceptable salts thereof, a process for the preparation of such liquid dosage forms, and use thereof. | 2009-08-06 |
20090197838 | ANTIMICROBIAL N-HALOGENATED AMINO ACID SALTS - The present invention relates to a formulation comprising a N-halogenated amino acid and a phase transfer agent. The present invention also describes a method for disinfecting and/or cleaning a contact lens comprising contacting a contact lens with a formulation comprising a N-halogenated amino acid salt for a time sufficient to disinfect and/or clean the lens. | 2009-08-06 |
20090197839 | Method of obtaining total fixed lipids from seeds of the sapodilla family, for the preparation of cosmetics and dermatological pharmaceutical compositions - Procedure for the obtaining a concentrate of the total fixed lipids of the kernels of the family Sapotaceae, genus | 2009-08-06 |
20090197840 | COMPOSITION AND METHOD FOR ENHANCING SKIN CELL GROWTH, PROLIFERATION AND REPAIR - A skin treatment composition is provided which contains calcium glycerophosphate and a fatty acid source derived from an animal or a vegetable. The composition enhances skin cell proliferation and growth and repair of damage to skin cells. Methods for enhancing skin cell repair, proliferation, and growth and for enhancing ceramide synthesis involve topically applying to the skin a composition containing calcium glycerophosphate and a fatty acid source derived from an animal or a vegetable. | 2009-08-06 |
20090197841 | Inhalant Propellant-Free Aerosol Formulation - The invention relates to inhalant propellant-free aerosol formulations containing at least one inert, non-volatile auxiliary substance for adjusting defined droplet sizes. | 2009-08-06 |
20090197842 | Therapeutic Agent for Neuropathic Pain - The present invention provides a therapeutic agent for neuropathic pain having an excellent treating effect on neuropathic pain, which is an intractable disorder. More specifically, the present invention provides a therapeutic agent for neuropathic pain and a pharmaceutical composition for treating neuropathic pain, comprising (1) a compound having an anti-progesterone activity (for example, fulvestrant (ICI | 2009-08-06 |
20090197843 | Treatment of Prevention of Unscheduled Bleeding in Women on Progestogen Containing Medication - The present invention relates to a method of treating or preventing unscheduled bleeding in women, the unscheduled bleeding being the result of repeated administration of a hormonal composition that contains a progestogen, wherein the method includes the administration of an effective amount of Renin Angiotensin System (RAS) suppressor selected from angiotensin converting enzyme inhibitors; angiotensin II receptor antagonists; renin inhibitors and combinations thereof. Other aspects of the invention relate to a pharmaceutical composition containing a RAS suppressor and a progestogen and to a pharmaceutical kit having a plurality of dosage units, wherein at least one dosage unit contains a progestogen; at least one dosage unit contains an estrogen; and at least one dosage unit contains a RAS suppressor. | 2009-08-06 |
20090197844 | Demethylpenclomedine Analogs and Their Use as Anti-Cancer Agents - This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders. In one embodiment the analogs are represented by the formula | 2009-08-06 |
20090197845 | Method for treating olfactory disorder - Disclosed is a method for treating olfactory disorders, which comprises administering to a patient a therapeutically effective amount of 3-β-hydroxymethylglutarate CoA (HMG-CoA) reductase, which has excellent effects of protecting and regenerating olfactory nerve. | 2009-08-06 |
20090197846 | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods - Pharmaceutical compositions suitable for administration into the interior of an eye of a person or animal are described. The present compositions include one or more components which are effective in providing a reduced toxicity relative to existing intraocular ophthalmic compositions. The present compositions include one or more therapeutic agents in amounts effective in providing a desired therapeutic effect when placed in an eye, and one or more retinal friendly excipients that have a reduced toxicity relative to benzyl alcohol or polysorbate 80. In certain compositions, the excipient component of the compositions comprises one or more cyclodextrins or cyclodextrin derivatives. Methods of using the compositions to treat ocular conditions are also described. | 2009-08-06 |
20090197847 | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods - Pharmaceutical compositions suitable for administration into the interior of an eye of a person or animal are described. The present compositions include one or more components which are effective in providing a reduced toxicity relative to existing intraocular ophthalmic compositions. The present compositions include one or more therapeutic agents in amounts effective in providing a desired therapeutic effect when placed in an eye, and one or more retinal friendly excipients that have a reduced toxicity relative to benzyl alcohol or polysorbate 80. In certain compositions, the excipient component of the compositions comprises one or more cyclodextrins or cyclodextrin derivatives. Methods of using the compositions to treat ocular conditions are also described. | 2009-08-06 |
20090197848 | Synthetic mimics of mammalian cell surface receptors: method and compositions - The present invention relates to new synthetic receptors. More particularly, the present invention relates to the use of the synthetic receptors for delivering a protein, peptide, drug, prodrug, lipid, nucleic acid, carbohydrate or small molecule into a target cell via receptor-mediated endocytosis. According to the invention, novel synthetic mimics of cell surface receptors have been designed and methods for use of the same are disclosed. | 2009-08-06 |
20090197849 | TRANSDERMAL AND TOPICAL ADMINISTRATION OF DRUGS USING BASIC PERMEATION ENHANCERS - Methods are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of pharmacologically or cosmeceutically active agents. The methods entail the use of a base in order to increase the flux of the active agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. The permeation enhancer can be an inorganic or organic base. Compositions and transdermal systems are also described. | 2009-08-06 |
20090197850 | Coatings Comprising Self-Assembled Molecular Structures - A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic substance from the implantable device. | 2009-08-06 |
20090197851 | THERAPY AND USE OF COMPOUNDS IN THERAPY - A method of treating, preventing or ameliorating chronic heart failure or acute heart failure in a patient the method comprising administering to the patient an effective amount of: a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule, for example LPS binding protein, BPI, lipoproteins, bile acids or an antibody capable of binding LPS, a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule or bacterium in the gut, for example charcoal, a bile acid or Fuller's earth, an antibacterial agent that is substantially active in the gut, an agent that is able to inhibit the response by a cell to endotoxin (lipopolysaccharide; LPS), an agent that may form a barrier or that otherwise impedes translocation of bacteria or endotoxin (LPS) from the gut into the patient's circulation. A method of treating, preventing or ameliorating endotoxin-mediated immune activation in acute or chronic heart failure in a patient the method comprising administering to the patient an effective amount of: a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule, for example LPS binding protein, BPI, lipoproteins, bile acids or an antibody capable of binding LPS, a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule or bacterium in the gut, for example charcoal, a bile acid or Fuller's earth, an antibacterial agent that is substantially active in the gut, an agent that is able to inhibit the response by a cell to endotoxin (lipopolysaccharide; LPS), an agent that may form a barrier or that otherwise impedes translocation of bacteria or endotoxin (LPS) from the gut into the patient's circulation. | 2009-08-06 |
20090197852 | Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor - A method for treating a breast cancer in a subject by administering 17-allylamino-17-demethoxy-geldanamycin (17-AAG) or 17-amino-17-demethoxygeldanamycin (17-AG), or a prodrug of either 17-AAG or 17-AG, in combination with a HER2 inhibitor. | 2009-08-06 |
20090197853 | METHODS AND COMPOSITIONS OF TREATING CANCER - The present disclosure involves the use of metal-containing texaphyrins and zinc (II) reagents for the treatment of tumors, atheromas and other neoplastic tissue. The present application demonstrates increased oxidative stress, alterations in zinc homeostasis, cell cycle arrest, and apoptosis of cancer cells in the presence of texaphyrins and/or zinc. One aspect is to monitor oxidative stress and/or alterations in zinc homeostasis in target cells prior to and/or after treatment with metal-containing texaphyrins and/or zinc (II) reagents as a predictor for treatment efficacy. The present disclosure provides molecular basis for the cell cycle arrest and apoptosis on cancer cells in the presence of texaphyrins and zinc. Another aspect is to monitor different genes involved in response to treatment with texaphyrins and zinc prior to and/or after treatment as predictors for treatment efficacy. | 2009-08-06 |
20090197854 | USE OF PICOPLATIN TO TREAT COLORECTAL CANCER - The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. Dosages, dosing schedules, and ancillary treatments are described. | 2009-08-06 |
20090197855 | PHARMACEUTICAL COMPOSITIONS OF CEFDINIR - A chewable tablet dosage form comprising Cefdinir or pharmaceutically acceptable salts thereof for the oral administration of Cefdinir in a manner that is more palatable and less objectionable to population group's especially young children and older patients. A method of preparing the chewable tablets comprising Cefdinir and method of treatment using the same. | 2009-08-06 |
20090197856 | ANTIVIRAL COMPOUNDS - Provided are compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds and compositions are useful for treating viral infections caused by the Flaviviridae family of viruses. | 2009-08-06 |
20090197857 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES - The present invention provides novel substituted amino-azetidines that are useful as cannabinoid receptor antagonists/inverse agonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, dyslipidemias, cardiovascular disorders, hepatic disorders, and a combination thereof. | 2009-08-06 |
20090197858 | HYPERCHOLESTROLEMIA AND TENDINOUS INJURIES - This invention provides compositions and methods of inhibiting, suppressing, or treating a tendinous or musculoskeletal soft tissue injury. The invention further provides a method of ameliorating symptoms associated with a tendinous or musculoskeletal soft tissue injury. Additionally, the invention provides methods for evaluating the risk of developing a tendinous or musculoskeletal soft tissue injury. | 2009-08-06 |
20090197859 | Pyridinyl Amides for the Treatment of CNS and Metabolic Disorders - The present invention relates to novel pyridinyl derivatives of Formula | 2009-08-06 |
20090197860 | BIARYL SUBSTITUTED DIAZABICYCLOALKANE DERIVATIVES - The invention relates biaryl substituted diazabicycloalkanes, and more particularly bicycloheteroaryl substituted fused diazabicycloalkane derivatives, compositions comprising such compounds, and methods of preventing or treating conditions and disorders using such compounds and compositions. | 2009-08-06 |
20090197861 | INHIBITORS OF INTEGRIN ALPHA2BETA1 WITH MODIFIED UREA MOIETY - Novel compounds inhibiting the integrin α2β1/GPIa-IIa receptor are disclosed. Also disclosed are pharmaceutical compositions containing the compounds, as well as methods of their therapeutic use. The compounds disclosed are useful, inter alia, as inhibitors of integrin α2β1/GPIa-IIa-mediated activity. | 2009-08-06 |