26th week of 2022 patent applcation highlights part 8 |
Patent application number | Title | Published |
20220202619 | HEMOSTATIC PASTE AND METHODS OF MAKING THEREOF - The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol. | 2022-06-30 |
20220202620 | Manifold With Biological Actives For Negative-Pressure Therapy - A system for use in treating a tissue site with negative pressure, which may comprise a dressing or tissue interface and a plurality of standoffs for storing and releasing a biocompatible polymer to the tissue site. The standoff may be cells or closed-end cells. In some examples, the biocompatible polymer may comprise collagen, oxidized regenerated cellulose, or a combination thereof. Method for using and manufacturing the dressing or tissue interface may also be disclosed. | 2022-06-30 |
20220202621 | MEDICAL PAD - Implementations of a medical pad comprise a perimeter side, a first surface, a second surface, and a plurality of openings. In some implementations, a method of using the medical pad comprises positioning the medical pad on an area susceptible to the development of a bedsore or similar wound, such as a bony prominence or pressure point, to prevent the development of a bedsore or similar wound, and another method comprises positioning the medical pad on a bedsore or similar wound to help the treatment and healing of the bedsore or similar wound. | 2022-06-30 |
20220202622 | Hybrid Adhesive Tissue Cover With Application Stretch - A cover for protecting a tissue site may comprise a shell layer, an adhesive disposed on the shell layer, and a contact layer disposed adjacent to the adhesive. The contact layer may have a first pattern of apertures and bridges, and the shell layer may have a second pattern of apertures overlaying the bridges. In some examples, the adhesive may have a bond strength that is greater than the tensile modulus of the shell layer. The contact layer may have an open area of about 40 percent to about 50 percent of the total area of the contact layer. A release liner may be disposed adjacent to the contact layer. Perforations through the shell layer and the contact layer can define a sacrificial segment configured to be separated from the shell layer and the contact layer. A handling bar may be coupled to the sacrificial segment. | 2022-06-30 |
20220202623 | Dressing - Provided is a dressing, including: a skin-friendly layer, a fluid transport structure, and an upper cover. The skin-friendly layer has first extraction guide holes and first injection guide holes. The fluid transport structure, formed on the skin-friendly layer, has an extraction guide groove, second extraction guide holes, an injection guide groove and second injection guide holes, wherein the extraction guide groove separates from the injection guide groove, the second extraction guide holes are formed in the extraction guide groove and communicate with the first extraction guide holes, and the second injection guide holes are formed in the injection guide groove and communicate with the first injection guide holes. The upper cover, formed on the fluid transport structure, has an extraction hole communicating with the extraction guide groove and the second extraction guide holes, and an injection hole communicating with the injection guide groove and the second injection guide holes. | 2022-06-30 |
20220202624 | SELF-ADHESIVE SILICONE GEL LOADED WITH MICROPARTICLES, PARTICLES WITH IMPROVED ADHESION - The invention relates to the use of microparticles in a self-adhesive silicone gel to increase adhesion. The invention relates to a self-adhesive silicone gel that comprises microparticles and has improved adhesion properties, in particular when same also comprises additional chemical compounds/derivatives, more particularly compounds that are active, soluble or miscible in the silicone gel. | 2022-06-30 |
20220202625 | METHOD FOR MANUFACTURING WORN ARTICLE - A method including: a step of carrying first and second continuous webs in a predetermined carrying direction; a first slitting step of slitting the first continuous web along a virtual first cut-off line extending the carrying direction, thereby dividing the first continuous web into a wider first divided web and a narrower second divided web; a step of sandwiching an around-torso elastic member extending in a girth direction between the wider first divided web and the second continuous web; a welding step of welding together the first divided web, the second continuous web and the around-torso elastic member intermittently in the carrying direction, thereby producing a layered sheet; and a bonding step of sandwiching an around-leg elastic member meandering relative to the carrying direction between the layered sheet and the narrower second divided web, and attaching the around-leg elastic member thereto by an adhesive, thereby producing a stretchable continuous sheet. | 2022-06-30 |
20220202626 | SENSING PANEL FOR HYGIENE MONITORING DEVICE - A flexible sensing panel includes a flexible substrate having first and second major surfaces, first and second separated side edges, and first and second ends, the flexible substrate being at least partly disposed between a flexible protective layer and a flexible fastening layer, and at least one sensing element being disposed on the flexible substrate. The protective layer is secured to the first major surface of the flexible substrate and is folded over the first and second side edges onto the second major surface of the flexible substrate and secured thereto to position at least part of the first and second side edges within the so formed folds, and wherein the fastening layer is at least partly disposed on the second major surface of the flexible substrate and secured thereto. | 2022-06-30 |
20220202627 | SENSOR UNIT, ABSORBENT ARTICLE KIT, AND ABSORBENT ARTICLE PACKAGE - A sensor unit for an absorbent article includes: a urine change-detection unit that detects a change in color of a urine indicator that visually changes a color on contact with urine; and a feces change-detection unit that detects a change in color of a feces indicator that visually changes a color on contact with feces. | 2022-06-30 |
20220202628 | ABSORBENT PRODUCT - An absorbent article includes: a liquid absorbent body; a feces indicator that visually changes between two colors, the feces indicator changing, on contact with feces, from a pre-feces-contact color to a post-feces-contact color; and a urine indicator that visually changes between two colors, the urine indicator changing, on contact with urine, from a pre-urine-contact color to a post-urine-contact color, the feces indicator and the urine indicator being disposed on a non-skin side in a thickness direction with respect to the absorbent body, and one of the two colors of the feces indicator being visually similar to one of the two colors of the urine indicator, whereas the other of the two colors of the feces indicator being visually dissimilar to the other of the two colors of the urine indicator. | 2022-06-30 |
20220202629 | TECHNIQUES FOR URINE AND FECES CONTAINMENT BRIEF WITH SLING - Provided is a containment brief to be worn by a user for containing urine and feces. The containment brief includes a strip of stretchable resilient material having a first end and a second end, a first stretchable resilient side panel attached to the strip of stretchable resilient material along a first side of the strip of stretchable resilient material between the first end and the second end, a second stretchable resilient side panel attached to the strip of stretchable resilient material along a second side of the strip of stretchable resilient material between the first end and the second end, the first side of the strip of stretchable resilient material being opposite the second side of the strip of stretchable resilient material, a first side dam disposed along the first side of the strip of stretchable resilient material, a second side dam disposed along the second side of the strip of stretchable resilient material, an absorbent pad disposed on a first surface of the strip of stretchable resilient material, the absorbent pad including a rectangular cut-out therein, and a sling disposed on the absorbent pad at least partially around the rectangular cut-out, wherein each of the first stretchable resilient side panel and the second stretchable resilient side panel includes at least one adhesive tab. | 2022-06-30 |
20220202630 | MATERIAL INCLUDING CHANNEL FOR IMPROVED FLUID DISTRIBUTION - A material for distributing fluid can include a first side edge, a second side edge, a first end edge, and a second end edge. The material can include a first surface and a second surface opposite from the first surface. The material can be liquid impermeable and at least one of the first surface and the second surface include at least one channel. The channel can include a channel width, a channel length, and a channel depth. The channel width can be from 0.1 mm to 2.5 mm. The channel depth can be configured such that the channel does not extend completely through the material. | 2022-06-30 |
20220202631 | Pantiless Liner - The invention relates to panty liners, and more particularly to a Pantiless Liner that has adhesive on the upper side. This Pantiless Liner helps to keep women dry, gives protection while maintaining a sleek look in your clothing. (1) Designs will be made with silicone or self-adhesive strips that is sensitive to the skin and will stick to the women's inner thigh. (2) Aims to produce liners that will give women the protection and comfort needed when wearing skirts, skinny jeans, leggings, and other clothing that won't show an uneven panty line when wearing pants. (3) Without having a fear of vaginal discharge or secretion in your clothing. (4) Also caters for post-intercourse discharge and slight urinary leakage due to a weak bladder. (5) Due to the silicone or adhesive strips on the upside of the product and will securely stick to the inner thigh of the body, the Pantiless Liner is an innovative product not currently on the market, it's super beneficial when young girls and women who are athletic or just lounging who has no desire to wear panties but needs the comfort and protection of vaginal because of natural discharge, secretion or moisture of the vaginal. | 2022-06-30 |
20220202632 | Patient Transport Apparatus With Auxiliary Wheel System - A patient transport apparatus transports a patient over a floor surface. The patient transport apparatus comprises a support structure and support wheels coupled to the support structure. An auxiliary wheel is coupled to the support frame to influence motion of the patient transport apparatus over a floor surface. The auxiliary wheel is movable to a deployed position with the auxiliary wheel engaging the floor surface and a stowed position with the auxiliary wheel spaced a distance from the floor surface. An actuator assembly including a lift actuator a biasing device, and a biasing load adjustment assembly. The lift actuator is operable to move the auxiliary wheel to the deployed position and to the stowed position. The biasing device configured to bias the auxiliary wheel towards the deployed position. The biasing load adjustment assembly configured to adjust a biasing force being applied by the biasing device to the auxiliary wheel. | 2022-06-30 |
20220202633 | PORTABLE POWER ASSIST FOR MANUAL WHEELCHAIRS - Apparatus and associated methods relate to a wheelchair power assist device configured to switch a motorized friction roller between engaged and disengaged modes with a wheelchair wheel, based on an engagement actuator configured to move the friction roller relative to an attachment member removably secured to the wheelchair. The friction roller may be operably coupled with an engagement member configured to move relative to the attachment member. The engagement member may be moved by an extendable and retractable actuator shaft coupled with the attachment member. A manual wheelchair may be converted to a powered wheelchair using a motorized friction roller for each wheelchair wheel. A plurality of power assist devices may be configured to position a respective plurality of friction rollers to leave an open space behind the wheelchair seating area, advantageously permitting the power assist devices to remain attached to a foldable wheelchair in either folded or unfolded configurations. | 2022-06-30 |
20220202634 | Patient Support Apparatus With Adaptive User Interface - A patient support apparatus for patients. The patient support apparatus comprises a base and a litter supported by the base. The patient support apparatus also comprises powered devices that perform one or more predetermined functions on the patient support apparatus. A user interface is employed to control the powered devices. The user interface is designed to enable caregivers to cause operation of the powered devices with fewer buttons, while retaining functionality in using powered devices. | 2022-06-30 |
20220202635 | AUTOMATIC CLEANING METHOD AND CLEANING BED FOR PATIENT OF GATISM - An automatic cleaning method and a cleaning bed for a patient of gatism are provided. The cleaning bed includes a bed body, a bed plate is arranged on the bed body and is provided with a through groove therein, a bed bottom plate is arranged on a lower part of the bed body, a lifting mechanism is arranged on the bed bottom plate and is provided with a soft cushion thereon, a fabric bracket is arranged under the bed plate and is provided with a material roller thereon, a pressing roller bracket is arranged under the bed plate and at one side close to the fabric bracket and is provided with provided with a first pressing roller and a second pressing roller. | 2022-06-30 |
20220202636 | ISOLATION TENT - Apparatus for use in providing isolation, the apparatus including an isolation tent having a body including a roof member, at least one wall extending between a supporting surface and the roof member in use to thereby at least partially define an internal volume substantially isolated from a surrounding environment, a plurality of connectors coupled to the body, the plurality of connectors being adapted to physically attach the body to a frame and an electrical component electrically connected to at least one of the plurality of connectors to allow electrical signals to be transferred to or from the electrical component via the connector. | 2022-06-30 |
20220202637 | Assembling Negative Pressure Isolation Chamber - The invention discloses an assembly type negative pressure isolation chamber, in which the necessary configuration of the negative pressure isolation ward is contained in a hexahedral chamber. The chamber forms an independent building assembly unit, which can be integrated into or removed from the building system. The chamber can also be disassembled and transported, and the switching of use functions can be realized through the flexible combination and simple modification of components. The indoor wall of the chamber is light Clean and washable materials are integrated with furniture. The air conditioning system adopts internal circulation return air and independent temperature regulating device. The sewage pre disinfection link is added to the sewage system. The negative pressure isolation chamber can help the medical isolation building system expand rapidly in case of respiratory infectious disease outbreak and can carry out space mobility with the transfer of the epidemic situation. | 2022-06-30 |
20220202638 | INFANT CARE DEVICE INCLUDING PREDICTIVE FAILURE SIDE PANELS - An infant care device that can include a failure indicating feature in one or more of the side panels to discourage improper use of the side panels to move the infant care device. When a side panels is used to move the infant care device and a force greater than a pre-determined maximum is applied to the side panel, the failure indicting feature indicates such improper use. The failure indicating feature is designed to provide an indication at a level of force that is less than the level of force that would damage the hinge and latch assembly holding the side panel. The failure indicating feature can provide a physical indication or a visual indication when a force greater than a predetermined maximum is applied to the side panel. | 2022-06-30 |
20220202639 | RELOCATION MODULE AND METHODS FOR SURGICAL EQUIPMENT - An anesthetic equipment storage and waste air management module configured to housing electronic and electromechanical surgical equipment including a system to measure and record administration of one or more IV medications or fluids for IV administration. The module can include a housing having a lower section and a tower-like upper section, wherein the lower section is configured to house unrelated waste heat-producing electronic and electromechanical surgical equipment. The module can also include a cowling that substantially confines waste heat generated by the unrelated waste heat-producing electronic and electromechanical surgical equipment, and can include a system for measuring and recording the administration of the one or more IV medications and fluids. | 2022-06-30 |
20220202640 | Device and Method for Improved Muscle Contraction - A device and a method of applying vibration on a muscle for improving muscle contraction are disclosed. The device includes a motor. The device includes an adhesive strip. The adhesive strip is a reusable dual-sided adhesive strip. The adhesive strip removably mounts over a muscle or muscle group. The motor causes vibration and transmits the vibration to the muscle through the device and the adhesive strip, causing the user to concentrate on the muscle. The user detaches the device from one muscle or muscle group, and attaches to a different muscle or muscle group. The vibration caused by the motor helps the user to concentrate on the muscle during exercise, assisting with mind-muscle connection, which helps to improve muscle contraction. | 2022-06-30 |
20220202641 | PHYSICAL CONDITIONING AND THERAPEUTIC CONDITIONING PIVOTING SYSTEM - A physical conditioning and therapeutic conditioning system that, when configured and incorporated into the construction of a chair, has a seat, a base configured to rest on a surface, and a seat-support mechanism which is configured to couple the seat to the base and enables the seat, when unlocked in one embodiment, to be pivoted in any direction while rocking in the seat and using one's own body weight for resistance. Ideally the seat-support mechanism permits universal motion in all directions above a vertical axis, including front to back inflection and side-to-side inflection of at least 40° , including 360° of rotation on a universal type joint. The universal type joint is a ball joint consisting of a bearing stud and socket enclosed in a case, with all parts made of steel. In one embodiment, the bearing stud is tapered and fits into a hydraulic post. A ball joint is used to allow free rotation in two planes at the same time. | 2022-06-30 |
20220202642 | ASSISTED WALKING DEVICE - A stable walking apparatus can be used to allow the elderly, disabled, injured, or infirmed to move for day-to-day activities and exercise. The apparatus supports the individual at an upper body portion, such as under the arms of the user. This allows use of the arms and legs of the individual, such as better balance and move with the device, while also controlling aspects of the device. The support is height adjustable, and also includes a braking system to both slow down and stop the user-apparatus. The braking system can be used with limited extremity functionality for greater use of the apparatus by a wide range of individuals. Swiveling wheels provide for additional functionality to use the device for more purposes and in increased locations. | 2022-06-30 |
20220202643 | HANDS-FREE NECK AND SHOULDER MASSAGER - A massager with heating features includes at least one massage head, one heating lamp, an upper housing, a carriage, a motor, one set of gear assembly, and a lower housing. | 2022-06-30 |
20220202644 | Clogged Duct Massager - A clogged duct massager includes a handle, a pair of arms each affixed at. a lower end to an upper end of the handle, and a massage roller having opposing sides that rotatably connect to the upper end of each arm, such that the massage roller is freely rotatable between the pair of arms. A power supply disposed within the handle is operably connected to a heating element and a vibration motor disposed within the massage roller. Temperature and vibration controls disposed on the handle allow the user to selectively activate or deactivate the heating element and the vibration motor. The massage roller pressure, heat, and vibration can be applied to any desired area of the skin in order to prevent and alleviate clogging of ducts and pores, thereby helping to prevent mastitis and other negative conditions associated with dogged ducts and pores. | 2022-06-30 |
20220202645 | HEAD UNITS FOR A TREATMENT DEVICE - A myofascial massager for mechanical treatment of a treatment location in a human subject's body. The massager includes an actuator which operates in a cyclical linear amplitude field for a few millimeters and at a frequency range from some Hz to a few dozen Hz. A head unit connected to the actuator includes a first portion having a higher rigidity, and a membrane having a second lower rigidity, which membrane comes into contact with the treatment location. | 2022-06-30 |
20220202646 | FOOT SPA TUB PUMP AND METHOD - A foot spa tub includes a tub basin, a first magnetic drive member rotatably coupled to a drive motor, and a first casing supporting the magnetic drive member. The first casing is disposed against an exterior surface of a sidewall of the basin. A second magnetic drive member is rotatably coupled to a blade. The first and second magnetic drive members are magnetically coupled to each other so that the blade is drivingly coupled to the drive motor. A nozzle houses the second magnetic drive member and the blade. The nozzle is detachably securable to an interior surface of the sidewall by a magnetic attraction force between the first and second magnetic drive members. A method of circulating liquid in a foot tub spa is also provided. | 2022-06-30 |
20220202647 | MASSAGE CONTROL METHOD AND ELECTRONIC DEVICE IMPLEMENTING MASSAGE CONTROL METHOD - A massage control method includes obtaining three-dimensional parameter data of a user, determining acupuncture points, a position of a first part, and a position of a second part of the user according to the three-dimensional parameter data, adjusting a position of a massage device according to the three-dimensional parameter data so that the position of the massage device corresponds to the three-dimensional parameter data, and aligning at least one massage component of the massage device with the acupuncture points according to the positions of the first part and the second part of the user. | 2022-06-30 |
20220202648 | PHARMACEUTICAL COMPOUNDING SYSTEM AND METHOD - A pharmaceutical compounding system includes a plurality of vials and a receptacle. The system is arranged to remove substances stored within the vials and combine them within the receptacle to form a medication, and each vial is continuously maintained gripped within the system during preparation of the medication. | 2022-06-30 |
20220202649 | Method for Controlling the Volume Flow Rate From a Nozzle - Methods for controlling or regulating the volume flow rate of a substance to be sprayed and/or a gas from a nozzle suitable for spraying substances, particularly dispersions, emulsions or suspensions, wherein the nozzle has a nozzle body comprising a nozzle mouthpiece, wherein the nozzle body has an inner pipe, which is connected to a supply for the substance to be sprayed and has an inner wall and a discharge port, and an outer pipe, which is spaced from the inner pipe, is connected to a supply for a gas and has a discharge port, and the discharge port of the inner pipe and the discharge port of the outer pipe are arranged in the region of the nozzle mouthpiece. | 2022-06-30 |
20220202650 | MEDICINE-TAKING DETECTION SYSTEM AND INGESTION DEVICE - A medicine-taking detection system is provided that includes an ingestion device | 2022-06-30 |
20220202651 | Medicine Delivery Device - A medicine delivery device for delivering a predetermined daily dosage of prescription pills to a patient includes a container having a continuous outer wall and a closed bottom that, together, define an open interior area and an open top. Pills, tablets, capsules, and even liquid medicaments may be received in the interior area. A closure member may be releasably coupled to an upper edge of the outer wall for closing the open top of the container. The outer wall of the container consists of a hemp-fiber reinforced biopolymer. | 2022-06-30 |
20220202652 | SENSING RETRIEVAL OF PILLS - A system for dispensing pills may include a plurality of containers, a retrieval arm movable into the plurality of containers to retrieve contents from the plurality of containers, a carrier supporting the plurality of containers, the carrier movable to adjust positions of the plurality of containers relative to a predetermined position, and a weighing assembly. The weighing assembly may include an actuator and a weight sensor. The actuator may be actuatable to control mechanical communication between the weight sensor and one of the plurality of containers at the predetermined position, and the weight sensor may be operable to measure weight of the one of the plurality of containers in mechanical communication with the weight sensor at the predetermined position. | 2022-06-30 |
20220202653 | FEEDING TUBE WITH INTEGRATED STYLET - A feeding tube with an integrated stylet, for use in less invasive surfactant therapy (LIST) procedures with pre-term infants, has a flexible feeding tube with distal and proximal ends and an adapter at the proximal end. A stylet with distal and proximal ends is positioned within the feeding tube and has an anchor at the proximal end. The anchor is configured to seat within the adapter to prevent the anchor from entering the feeding tube and has one or more channels extending through the anchor to permit fluid to flow from the adapter through the channels and through the feeding tube with the anchor remaining seated within the adapter. | 2022-06-30 |
20220202654 | Enteral Feeding Tube with Polygonal Configuration - A tube received, at least in part, by a breastmilk warmer includes a first segment having a first thermal conductivity, a second segment having a second thermal conductivity different from the first thermal conductivity, and a third segment having a third thermal conductivity different from at least one of the first and second thermal conductivities. The first segment is configured to be coupled to a source of fluid. The second segment is fluidly coupled to the first segment and disposed in a labyrinthine manner within a breastmilk warmer. The third segment is fluidly coupled to the second segment and is configured to be coupled to a feeding apparatus. The tube also includes a fluid lumen extending from the first segment through the second segment and to the third segment. The fluid lumen has a uniform diameter from the first segment to the third segment. | 2022-06-30 |
20220202655 | REMINERALIZING DENTAL MATERIAL - A subject of the invention is a remineralizing dental material, having at least one cation and at least one anion, which are configured as partner ions for forming a remineralization substance. In accordance with the invention at least one of the partner ions is multivalent and is included as counterion in a coacervate. A further subject of the invention is a kit for producing such a dental material, and also the use thereof. | 2022-06-30 |
20220202656 | INDIUM-CONTAINING TRANSLUCENCY IMPROVING LIQUID FOR DENTAL ZIRCONIA CALCINED BODY - To provide a liquid for improving translucency for dental zirconia calcined body which may impart high translucency which is similar to an enamel of a natural tooth to a zirconia sintered body and a method for using thereof. | 2022-06-30 |
20220202657 | CALCIUM COACERVATES FOR REMINERALIZATION AND FOR DEMINERALIZATION INHIBITION - The invention relates to calcium coacervate for use in a method for caries prevention and/or caries treatment, comprising a step during which dental enamel is infiltrated with calcium coacervate; and to kits that comprise: a) a phosphate ion-containing solution; and b1) a calcium coacervate-containing emulsion and/or b2) a second solution comprising polyanions and/or their salts, and a calcium ion-containing third solution. | 2022-06-30 |
20220202658 | DENTAL COMPOSITION - Disclosed herein is a dental material containing a polymerizable hydrolysis stable polycyclic amide monomer. The present disclosure relates to methods of making and use of the polymerizable hydrolysis stable polycyclic amide monomer for the preparation of a dental polymerizable hydrolysis stable polycyclic amide monomer composition. The present disclosure further relates to a cured dental material obtained by polymerizing the dental material. | 2022-06-30 |
20220202659 | Medical and Dental Bioceramic Composition for Temporary Use - The present invention is related to a bioceramic composition for temporary intracanal medication ready for use which promotes the constant, controlled and balanced release of metal ions, hydroxyl (OH | 2022-06-30 |
20220202660 | Oolitic Aragonite Beads and Methods Therefor - Disclosed herein are compositions comprising oolitic aragonite particles, wherein the oolitic aragonite particles have an average particle size of between 100 nm to 1 mm, and a Hunter brightness level greater than 88. Further disclosed herein are personal care and/or cosmetic compositions, comprising a carrier and the aforementioned oolitic aragonite particles. Further disclosed herein are methods of making and using the oolitic aragonite particles. | 2022-06-30 |
20220202661 | (UADDP) Under Armor Deodorizer and Deodorant Pad - The (UADDP) Under Armor Deodorizer and Deodorant Pad, is a two-part system. It includes a disposable and /or a reusable deodorant pad which includes a deodorant gel insert. The deodorant pad comes in varying shapes and sizes to accommodate different armpits. The disposable pad will absorb the moisture, emit deodorant through the gel insert and is self-adhesive to the skin. It is easily removable. Both pads absorb the sweat, the deodorant provides the odor protection and the back of the pad surface traps the moisture and blocks it from staining the clothes. The reusable deodorant pad is used with a dry weave cotton material that is both breathable, and absorbs moisture. It includes a snap-able space where the deodorant insert can be placed, used, removed and then the deodorant pad can be washed. | 2022-06-30 |
20220202662 | PARTICLE-CONTAINING COMPOSITION - Disclosed are: a particle-containing composition that contains inorganic particles (A) and particles (B) other than the particles (A), wherein the inorganic particles (A) are at least one selected from the group consisting of easily disintegrable inorganic particles (A1) having an average particle diameter D | 2022-06-30 |
20220202663 | SUBSTANTIALLY SILICONE-FREE GELLED COMPOSITIONS - The present disclosure relates to substantially silicone-free gelled compositions. | 2022-06-30 |
20220202664 | BABY WASH/SHAMPOO - Materials and methods for formulating a baby wash/shampoo are provided herein. For example, this document provides materials and methods for formulating a foaming baby wash/shampoo compositions that contain natural ingredients and are not irritating to babies' skin and eyes. | 2022-06-30 |
20220202665 | CORE-SHELL ENCAPSULATE COMPOSITION COMPRISING A BENEFIT AGENT - Described is an encapsulated composition comprising at least one core-shell microcapsule. The at least one core-shell microcapsule comprises a core comprising at least one benefit agent and a shell surrounding the core. The shell comprises a polymeric stabilizer that is formed by combination of a polymeric surfactant with at least one aminosilane. Disclosed are also a method of preparing an encapsulated composition and a use of such an encapsulated composition to enhance the performance of perfume and/or cosmetic ingredients in consumer goods. | 2022-06-30 |
20220202666 | ORAL CARE COMPOSITION - Disclosed herein are an oral care composition comprising a magnesium aluminum phyllosilicate abrasive with a high pellicle cleaning ratio (PCR) and a low relative dentin abrasivity (RDA), a method of using said oral care composition, method of its preparation, and a kit encompassing it. | 2022-06-30 |
20220202667 | COSMETIC COMPRISING ULTRAVIOLET WAVELENGTH CONVERSION SUBSTANCE - There is provided a novel composition containing a UV wavelength conversion substance, a dispersant, a UV absorber and/or a UV scattering agent, and an oil content, wherein the blending amount of the dispersant is 1% by weight or more. | 2022-06-30 |
20220202668 | Dentifrice Composition Comprising Zinc Oxide and Zinc Citrate - Described herein are oral care compositions comprising a combination of zinc oxide and zinc citrate, and methods of preparing and using the same. | 2022-06-30 |
20220202669 | SKIN PERFECTING COSMETIC COMPOSITIONS AND METHODS OF USE - Skin tightening compositions for application to the skin for providing an instantaneous and dramatic improvement to the appearance of skin. The skin tightening compositions typically include an aqueous phase comprising about 5 to about 40 wt. % of water, one or more water dispersible pigments; and an oil phase comprising at least 5 wt. % of one or more hydrophobic film forming polymers, from about 1 to about 40 wt. % of one or more thickening agents, from about 30 to about 85 wt. % of one or more volatile hydrocarbon oils. | 2022-06-30 |
20220202670 | PERSONAL AND HOME CARE COMPOSITIONS COMPRISING FATTY ACIDS FROM TUNG SEED OIL AS ANTIMICROBIAL PRESERVATIVE - Disclosed herein are personal care and home care composition comprising the whole of fatty acids (unfractionated) of Tung seed oil ( | 2022-06-30 |
20220202671 | METAL SEQUESTERING COSMETIC COMPOSITION - A cosmetic composition including a metal chelation system includes a combination of ascorbic acid, ferulic acid and phytic acid in a carrier system that includes water, and further includes one or more other ingredients for providing one of a variety of forms of cosmetic products. The cosmetic composition demonstrates removal of free metal ions in material contacted with the cosmetic composition, the removal of free metal ions in a range from at least about 40% and up to about 99%. | 2022-06-30 |
20220202672 | BABY LOTION - Materials and methods for formulating skin care compositions suitable for use on babies and toddlers are provided herein. For example, this document provides materials and methods for formulating lotion compositions that contain natural ingredients, are not irritating to babies' skin, and can be used to moisturize and soothe dry skin. | 2022-06-30 |
20220202673 | Silicone-Free Personal Care Compositions and Methods for the Same - Silicone-free personal care compositions and methods for the same are disclosed. The personal care composition may include an emulsifying system having one or more surfactants, one or more emollients, and one or more conditioning agents. The personal care composition may include a natural origin index of greater than 95%. | 2022-06-30 |
20220202674 | COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS - The instant disclosure relates to cosmetic compositions that include an anionic surfactant having at least two carboxylate salt groups; a cationic surfactant, including a cationizable surfactant; a fatty alcohol; and a cosmetically acceptable solvent; wherein the molar ratio of the cationic surfactant to the anionic surfactant ranges from about 5:1 to about 1:5. Methods for using such cosmetic compositions are also provided. | 2022-06-30 |
20220202675 | COSMETIC COMPOSITION CAPABLE OF STRENGTHENING EPIDERMAL TIGHT JUNCTIONS FOR THE PREVENTION AND/OR TREATMENT OF ATOPIC DERMATITIS - The invention concerns a composition, advantageously cosmetic, comprising:
| 2022-06-30 |
20220202676 | COMPOSITIONS FOR ALTERING THE COLOR OF HAIR - The present disclosure relates to color-altering compositions. The compositions comprise a hair color-altering agent and at least one carboxylic acid. Certain compositions further comprise at least one amino acid or amino sulfonic acid, and/or a salt thereof selected from the group consisting of taurine, aspartic acid, cysteine, lysine, methionine, tyrosine, phenylalanine, carnitine, a salt thereof, and a mixture thereof. Also provided are kits and methods of using said color-altering compositions. | 2022-06-30 |
20220202677 | SHAVING AID COMPRISING A BENEFIT AGENT - A shaving aid including a lubricant and a benefit agent. The benefit agent is azoxystrobin. Also provided is hair removal device with a shaving aid and the shaving aid includes azoxystrobin. The shaving aid may be on-board the hair removal device or provided separately. The shaving aid may be a solid or a liquid. | 2022-06-30 |
20220202678 | PHOTOPROTECTIVE SYSTEM CONSISTING OF 4 SUNSCREENS - The present invention relates to a cosmetic or pharmaceutical composition comprising at least one cosmetically or pharmaceutically acceptable excipient and a photoprotective system consisting of:
| 2022-06-30 |
20220202679 | HAIR SHINE COMPOSITIONS - Hair shine compositions are disclosed. In embodiments, a hair shine composition may include greater than or equal to 50 wt/wt % and less than or equal to 95 wt/wt % water; greater than or equal to 0.5 wt/wt % and less than or equal to 3 wt/wt % propanediol; and greater than or equal to 0.25 wt/wt % and less than or equal to 2 wt/wt % dimethyl isosorbide. In embodiments, a wt/wt % ratio of propanediol to dimethyl isosorbide may be from 1.00:1 to 3.00:1. | 2022-06-30 |
20220202680 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL - The object of the present disclosure is a method for treating keratinous material, in particular human hair, involving applying the following to the keratinous material
| 2022-06-30 |
20220202681 | INCREASING THE STABILITY OF AGENTS FOR THE TREATMENT OF KERATINOUS MATERIAL - A method for treating keratinous material, in particular human hair, is disclosed. The method comprises applying to the keratinous material a first composition (A) and a second composition (B). The first composition (A) comprises (A1) less than about 10% by weight of water, and (A2) one or more organic C1-C6 alkoxy silanes and/or their condensation products. The second composition (B) comprises (B1) water, and (B2) one or more alkylene glycols of a particular formula (AG-I). A multi-component packaging unit (kit-of-parts) comprising the first composition (A) and the second composition (B) is also disclosed. | 2022-06-30 |
20220202682 | INCREASING THE STABILITY OF AGENTS FOR THE TREATMENT OF KERATINOUS MATERIAL - A method for treating keratinous material, in particular human hair, is disclosed. The method comprises applying to the keratinous material a first composition (A) and a second composition (B). The first composition (A) comprises (A1) less than about 10% by weight of water, relative to the total weight of the first composition (A), and (A2) one or more organic C1-C6 alkoxy silanes and/or condensation products thereof. The second composition (B) comprises (B1) water, and (B2) one or more fat components. A multi-component packaging unit (kit-of-parts) comprising the first composition (A) and the second composition (B) is also disclosed. | 2022-06-30 |
20220202683 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL - A method for treating keratinous material, in particular human hair, is disclosed. The method comprises applying to the keratinous material a first composition (A) and a second composition (B). The first composition (A) comprises (A1) less than about 10% by weight of water, and (A2) one or more organic C1-C6 alkoxy silanes and/or condensation products thereof. The second composition (B) comprises (B1) water, and (B2) one or more aromatic compounds of a particular formula (AR-I): Ra-OC(O)-Rb, where Ra, Rb each independently represent a C1-C30 alkyl group, a C2-C30 alkenyl group, a hydroxy C1-C30 alkyl group, or a polyhydroxy C2-C30 alkyl group. A multi-component packaging unit (kit-of-parts) comprising the first composition (A) and the second composition (B) is also disclosed. | 2022-06-30 |
20220202684 | ADENOSINE PHOSPHATE-CONTAINING O/W TYPE EMULSION COMPOSITION HAVING LOW VISCOSITY - The present disclosure provides an O/W emulsion composition,
| 2022-06-30 |
20220202685 | GEL-TYPE SKIN EXTERNAL COMPOSITION - The present invention addresses the problem of providing a gel-type skin external composition containing a L-ascorbic acid derivative, which has excellent shape retention, stability, and excellent feeling of use even when salts coexist in the composition. The above problem is solved by providing a gel-type skin external composition containing a L-ascorbic acid derivative, a nonionic synthetic water-soluble polymer, and a natural water-soluble polysaccharide. | 2022-06-30 |
20220202686 | COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS - The instant disclosure relates to cosmetic compositions that include a non-hydrophobically modified anionic polymer; a cationic surfactant, including a cationizable surfactant; a fatty alcohol; and a cosmetically acceptable solvent; wherein the pH of the composition is below 5. Methods for using such cosmetic compositions are also provided. | 2022-06-30 |
20220202687 | Use Of A Bio-Based Polymer In A Cosmetic, Dermatological Or Pharmaceutical Composition - The present invention relates to the use of a polymer in a cosmetic, dermatological or pharmaceutical composition, wherein the polymer is crosslinked or non-crosslinked, characterized in that the polymer comprises at least 9.49 mol-% of repeating units (a) according to Formula (1) wherein at least 10 wt.-%, preferably at least 20 wt.-% of the repeating units according to Formula (1) comprise from 28 wt.-% to 100 wt.-% bio-based carbon content, relative to the total mass of carbon in the repeating unit according to Formula (1), measured according to standard ASTM D6866-12, Method B | 2022-06-30 |
20220202688 | ADDITIVE FOR MEDICINAL AGENTS - Provided is an additive for a chemical agent, which is capable of improving the functions of various chemical agents. The additive for a chemical agent according to an embodiment of the present invention includes a polymer (I) containing 50 mol % to 100 mol % of a structural unit derived from an N-vinyl lactam-based monomer with respect to 100 mol % of structural units derived from all monomers, the additive for a chemical agent having an average particle diameter of 100 μm or less in a state of having been dried under a reduced pressure of 0.02 MPa or less at 100° C. for 1 hour. | 2022-06-30 |
20220202689 | OXIDATIVE HAIR CREAM COMPOSITION CONTAINING POLYMERIC COLORANT - This invention relates to an oxidative hair cream composition that contains at least one oxidative hair cream ingredient and at least one polymeric colorant. | 2022-06-30 |
20220202690 | Pearling Agent and Pearlescent Compositions - A pearling agent including a combination of low HLB surfactants and high HLB surfactants. | 2022-06-30 |
20220202691 | SKIN PERFECTING COSMETIC COMPOSITIONS AND METHODS OF USE - Skin tightening compositions for application to the skin for providing an instantaneous and dramatic improvement to the appearance of skin. The skin tightening compositions typically include an oil phase comprising at least 5 wt. % of one or more hydrophobic film forming polymers; about 1 to about 40 wt. % of one or more thickening agents; about 30 to about 85 wt. % of one or more volatile hydrocarbon oils; and an aqueous phase comprising about 5 to about 40 wt. % of water; and at least 2 wt. % of one or more hydrophilic film formers with Tg less than about 80° C. | 2022-06-30 |
20220202692 | NATURAL HYDRATING MOISTURIZER HAIR THERAPY OIL - A natural hydrating moisturizer hair therapy oil having as components coconut oil, tea tree, organic black castor oil, biotin, argon oil, and Jamaican mango and lime black castor oil extra dark. | 2022-06-30 |
20220202693 | COSMETIC COMPLEX AND USES THEREOF - The present invention describes a complex comprising a combination of raw | 2022-06-30 |
20220202694 | GENE EXPRESSION PROMOTER FOR SKIN BEAUTIFICATION - A gene expression promoter for skin beautification contains a fermented extract of aspergillus oryzae as an effective component. The gene expression promotor for skin beautification causes expression of at least one gene for skin beautification among BMP-2, TGFB1, CLDN7, HB-EGF, VEGF-A, LCE3D, and PPAR-D. The fermented extract of aspergillus oryzae is extracted using water after steamed rice as a raw material is fermented with aspergillus oryzae. | 2022-06-30 |
20220202695 | BIOTECHNOLOGICAL PRODUCTION OF FLAVORINGS FROM POMACES OF THE CURRANT, STRAWBERRY, RASPBERRY AND WINE INDUSTRY - The present invention relates to a biocatalytic process for producing an aroma substance or a mixture of aroma substances, comprising the steps of:
| 2022-06-30 |
20220202696 | AGENT FOR PROMOTING COLLAGEN PRODUCTION, MEDICAMENT, COSMETIC, AND METHOD FOR MANUFACTURING AGENT FOR PROMOTING COLLAGEN PRODUCTION - An agent for promoting collagen production, comprising a fermentation product of a Lamiaceae plant. | 2022-06-30 |
20220202697 | TRANSMUCOSAL DRUG DELIVERY DEVICES FOR USE IN CHRONIC PAIN RELIEF - Provided herein are methods for treating chronic pain by administering low doses of buprenorphine twice daily (or once daily) via a transmucosal drug delivery device. The methods and devices efficiently treat chronic pain without significant side effects. | 2022-06-30 |
20220202698 | EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS OF RIOCIGUAT - Provided herein are the extended release pharmaceutical composition suitable for once or twice daily dosing comprising riociguat and at least one or more pharmaceutically acceptable excipients. The present invention also relates to method for preparing extended release composition and method of using these dosage forms for the treatment of pulmonary hypertension and related diseases. The present invention provides extended release composition of riociguat which are expected to exhibit desired technical attributes such as assay, stability and release profile suitable for once or twice daily administration. | 2022-06-30 |
20220202699 | COMPOSITIONS FOR THE TREATMENT OF VIRAL PULMONARY INFECTIONS - The disclosure relates to a method for treating a viral pulmonary infection (e.g., COVID-19 infection), the method comprising the step of delivering a composition comprising at least one bronchodilator or a pharmaceutically acceptable salt thereof and at least one pulmonary surfactant or a pharmaceutically acceptable salt thereof to the airway of a subject in need of treatment for the pulmonary viral infection. | 2022-06-30 |
20220202700 | COMPOSITIONS FOR THE TREATMENT OF VIRAL PULMONARY INFECTIONS - The disclosure relates to a method for treating a viral pulmonary infection (e.g., COVID-19 infection), the method comprising the step of delivering a composition comprising at least one bronchodilator or a pharmaceutically acceptable salt thereof and at least one pulmonary surfactant or a pharmaceutically acceptable salt thereof to the airway of a subject in need of treatment for the pulmonary viral infection. | 2022-06-30 |
20220202701 | COMPOSITIONS AND METHODS TO PROMOTE WOUND HEALING - The present disclosure describes compositions and methods to promote wound healing. The compositions and methods include an interleukin-1 beta (IL-1β) receptor antagonist (IL-1Ra), such as anakinra. The IL-1Ra can be administered topically to a chronic wound including a diabetic ulcer. | 2022-06-30 |
20220202702 | GUIDING MUSCULOSKELETAL PROCEDURES - A method may include providing a syringe device having (a) a single needle, (b) a first syringe comprising saline with microbubbles, (c) a second syringe comprising a therapeutic compound, and (d) a connector coupling the single needle to the first syringe and to the second syringe. The method may further include guiding the single needle to an injection site of a patient; injecting, with the first syringe, a quantity of saline with microbubbles; confirming a desired position of the single needle, with ultrasound imaging, by identifying the microbubbles in the quantity of saline relative to a tip of the single needle and further relative to one or more anatomical landmarks visible with the ultrasound imaging; and injecting, with the second syringe, the therapeutic compound at the injection site. | 2022-06-30 |
20220202703 | IN SITU GEL-FORMING DELIVERY SYSTEMS, METHODS AND COMPOSITIONS - In situ gel-forming compositions are disclosed, which may comprise one or more absorbable polymers, solvents such as N-methyl-2-pyrrolidone, polyethylene glycol or DMSO, and one or more bioactive agents. The composition forms a hydrogel or semi-solid mass on contact with an aqueous environment. Methods of using in situ gel-forming composition for various applications are also disclosed | 2022-06-30 |
20220202704 | PHARMACEUTICAL PARENTERAL COMPOSITION OF DUAL GLP1/2 AGONIST - The present invention relates to pharmaceutical compositions suitable for parenteral administration in human subjects. In particular, the present invention relates to isotonic pharmaceutical compositions for parenteral administration. | 2022-06-30 |
20220202705 | THERMORESPONSIVE HYDROGEL CONTAINING POLYMER MICROPARTICLES FOR NONINVASIVE OCULAR BIOLOGIC DELIVERY - A method for sustained delivery of an agent to an ocular organ in a subject, comprising topically delivering to the ocular surface a liquid thermoresponsive hydrogel comprising agent-loaded polymer microparticles, wherein the agent is an antibody, a fusion protein, a chemokine, an interleukin, a growth factor, albumin, immunoglobulin, an interferon, a peptide, stem cell-conditioned media, plasma or serum. | 2022-06-30 |
20220202706 | SUSTAINED RELEASE BIODEGRADABLE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND CYCLOSPORINE - Provided herein are sustained release biodegradable intracanalicular insert comprising a hydrogel and cyclosporine, methods of treating or preventing an ocular disease in a subject in need thereof by administering such inserts as well as methods of manufacturing such inserts. | 2022-06-30 |
20220202707 | THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 2022-06-30 |
20220202708 | EXPANDABLE GASTRORETENTIVE DOSAGE FORM - An oral gastro-retentive delivery device is provided which unfolds rapidly upon contact with gastric juice. The device is configured in a collapsed configuration for oral intake and unfolding for gastric retention for a predetermined period of time and eventually reducing in size for passage through the rest of the GI track. | 2022-06-30 |
20220202709 | EXPANDABLE GASTRORETENTIVE DOSAGE FORM - An oral gastro-retentive delivery device is provided which unfolds rapidly upon contact with gastric juice. The device is configured in a collapsed configuration for oral intake and unfolding for gastric retention for a predetermined period of time and eventually reducing in size for passage through the rest of the GI track. | 2022-06-30 |
20220202710 | WATER-SOLUBLE FORMULATIONS, METHODS OF MAKING AND USE - Water-soluble formulations including cannabinoids or a cannabis-derived compound for use in beverages and foods, methods of preparing the formulations, and methods of preparing beverages and foods including the formulations are disclosed herein. In other embodiments are provided water-soluble formulations that are physically and chemically stable, transparent or translucent in colour, calorie-free, and have minimal flavour. | 2022-06-30 |
20220202711 | Treatment of Diabetes Mellitus by Long-Acting Formulations of Insulins - The application relates to an aqueous pharmaceutical formulation for use in the treatment of Type I or Type II Diabetes Mellitus, wherein the treatment reduces the risk of nocturnal hypoglycemia, said formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine, with the proviso that the concentration of said formulation is not 684 U/mL of insulin glargine. | 2022-06-30 |
20220202712 | SELF-EMULSIFYING DRUG DELIVERY SYSTEMS FOR DELIVERY OF LIPOPHILIC COMPOUNDS - The present disclosure provides self-emulsifying drug delivery systems for delivery of lipophilic compounds, compositions, kits and unit dosage forms thereof, as well as processes for their preparation. | 2022-06-30 |
20220202713 | Curcumin Solubilisate - A solubilize composed of curcumin in a quantity of less than or equal to 10% by weight, preferable less than or equal to 7.5% by weight, particularly preferable 6% by weight, and at least one emulsifier having an HLB value in the range between 13 and 18, in particular polysorbate 80 or polysorbate 20 or a mixture of polysorbate 20 and polysorbate 80, wherein the average diameter of the micelles loaded with curcumin in between 5 nm and 40 nm, preferable between 6 nm and 20 nm, particularly preferable between 7 nm and 10 nm. | 2022-06-30 |
20220202714 | CELL PENETRATING PEPTIDE (CPP)-MEDIATED EV LOADING - The present invention relates to methods for loading extracellular vesicles (EVs) with a pharmacological agent. The invention discloses the use of cell-penetrating peptides as carriers into EVs, using either a non-covalent or covalent loading approach. Furthermore, the present invention pertains to medical uses and compositions comprising such pharmacological agent-loaded EVs. | 2022-06-30 |
20220202715 | DYNAMIC CLUSTERS OF ATOM PARTICLES ACTIVATED IN EXTRACELLULAR FLUID - Provided herein are dynamic clusters of atom particles activated in extracellular fluid intended to reverse the accumulation of advanced glycation end products which are closely related to chronic diseases. The manufacturing process involves material preparation, particle fragmentation, pH adjustment, selection of atom particles and construction of dynamic clusters through electro-magnetic field and flow velocity adjustment, and separation of dynamic clusters from the liquid. The dynamic clusters of atom particles deal with advanced glycation end products, which are diverse in chemical nature, by responding to irregularities in the electromagnetic field disrupted by highly reactive free radicals advanced glycation end products emit. Such mechanism makes it possible to extend the applications to diseases related to irregular free radical activities other than chronic diseases like in HIV replication or neural signalling. | 2022-06-30 |
20220202716 | EMPTY POROUS PARTICLES FOR USE IN TREATMENT, PREVENTION AND/OR POSTPONEMENT OF DEGENERATION OF NEURODEGENERATIVE DISEASES, NEURONS AND GLIA - The present invention relates to empty porous particles having a diameter between 0.1 and 1000 μm, as measured by e.g. SEM, for use in diagnosis, prevention and/or postponement of neurodegenerative diseases, or for prevention and/or postponement of degeneration of neurons and glia. The invention also relates to a method of identifying biomarkers for use in diagnosis. | 2022-06-30 |
20220202717 | Novel Method for Obtaining Efficient Viral Vector-Based Compositions for Vaccination or Gene Therapy - The present invention relates to a method for preparing viral vector-based compositions wherein the viral vector-based particles present in the composition have a particle size distribution with a polydispersity index (PDI) of less than 0.5, the method comprising the steps: (a) providing replication-deficient viral vectors; (b) providing a solution comprising at least one sugar and at least three different excipients selected from hydrophilic and amphiphilic excipients, wherein the excipients are characterized by polar, aliphatic, aromatic, negatively charged, and/or positively charged functional groups, and wherein the solution is further characterized by an excipient-sugar ratio of at least 1:2 (w/w); and (c) mixing the replication deficient viral vectors of step (a) with the solution of step (b). The present invention further relates to a viral vector-based composition obtainable by the method of the invention as well as to the viral vector-based composition of the invention for use as a prime-boost vaccine. | 2022-06-30 |
20220202718 | Cleavable Lipids - Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent iransfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids. | 2022-06-30 |