15th week of 2014 patent applcation highlights part 30 |
Patent application number | Title | Published |
20140099201 | Energy Recovery of Accelerating Slipstream - One embodiment comprising a motoring propeller ( | 2014-04-10 |
20140099202 | TURBOMACHINE PROPELLER BLADE SETTING DEVICE - The main subject matter of the invention is a device ( | 2014-04-10 |
20140099203 | MECHANICAL AND OTHER IMPROVEMENTS OF A VERTICAL AXIS WIND TURBINE - In an embodiment, a vertical axis wind turbine may be constructed to better survive wear and tear while being more energy efficient. A turbine blade may capture air movement to generate power. A blade arm may hold the turbine blade parallel to a rotating shaft. The blade arm may transmit torque from the turbine blade to the rotating shaft to drive a rotor of an electrical power generator. A moment-free connector may connect the turbine blade to the blade arm to transmit a stress maxima to a structural strongpoint of the turbine blade away from the moment-free connector. | 2014-04-10 |
20140099204 | BRAKING DEVICES FOR VERTICAL AXIS WIND TURBINES - Braking devices for wind turbines having a vertical axis are disclosed. An example braking device includes a flap able to tip about a tipping axis. The example flap has a center of gravity positioned outside the tipping axis. In addition, the example braking device disclosed herein includes a torque limiter having a disengagement torque. In addition, the example flap is mounted on the torque limiter, and the torque limiter is to allow the flap to tip through a tipping angle about the tipping axis for a rotational speed of the flap about the vertical axis which induces a torque at the torque limiter greater than or equal to the disengagement torque. | 2014-04-10 |
20140099205 | CLEAT FOR OPEN-WORK BLADE FOOT - The principal aim of the invention is a cleat ( | 2014-04-10 |
20140099206 | PROPELLER COMPRISING A COUNTERWEIGHT SYSTEM PROVIDED WITH AN AIR DISCHARGE CHANNEL - The main aim of the invention is a propeller ( | 2014-04-10 |
20140099207 | FAN BLADE SYSTEM WITH MULTIPLE SPACED LAYERS OF BLADES AND CENTRIFUGAL FAN USING SAME - A fan blade system with multiple spaced layers of blades and a centrifugal fan using same are disclosed. The centrifugal fan includes a housing, in which the fan blade system is mounted. The fan blade system includes a hub, and a first and a second blade group outward extended from a circumferential wall of the hub to axially space from each other. The housing includes a main housing portion and a secondary housing portion integrally formed on one side of the main housing portion. When the fan blade system is mounted in the housing, the two blade groups are separately located in the main housing portion and the secondary housing portion to produce higher airflow pressure and more air volume. With these arrangements, the centrifugal fan can have upgraded performance and be manufactured with reduced labor, time and material costs. | 2014-04-10 |
20140099208 | VERTICAL AXIS WIND TURBINE WITH SELF-STARTING CAPABILITIES - A vertical axis wind turbine and vertical axis wind turbine assembly comprising a rotary body and a plurality of blades. A cross section through each blade of the plurality of blades transverse to the rotary axis comprises an inner camber line, an outer camber line, and a chord line. The outer camber line comprises a first portion, a transition portion and a second portion. The second portion is longer, in the lengthwise direction, than a combined length of the first portion and the transition portion. The average second portion thickness is less than half an average first portion thickness. A magnitude of an average rate of change in a transition portion thickness is at least twice a magnitude of an average rate of change in a first portion thickness, and a magnitude of an average rate of change in a second portion thickness. | 2014-04-10 |
20140099209 | GAS TURBINE COMPONENT, METHOD FOR ITS PRODUCTION AND CASTING MOLD FOR USE OF THIS METHOD - A method is provided for casting a gas turbine component having at least a first section and a second section. As per the method, a liquid metal is cast into a casting mold and solidification of the metal is induced by means of controlled cooling. The cooling of the liquid metal in the first section is controlled in such a way that the metal solidifies in a directionally solidified crystal structure or a single-crystal structure. In the second section the cooling is carried out in such a way that it solidifies in a multidirectional crystal structure. | 2014-04-10 |
20140099210 | SYSTEM FOR GAS TURBINE ROTOR AND SECTION COUPLING - A system, including a first turbomachine rotor disk, a first annular protrusion with a first spline coupled to the first turbomachine rotor disk, a second turbomachine rotor disk, and a second annular protrusion with a second spline coupled to the second turbomachine rotor disk, wherein the first and second splines are coupled to one another. | 2014-04-10 |
20140099211 | Detection of Well Fluid Contamination in Seabed Fluids of Well Pump Assemblies - A submersible well pump assembly include a rotary pump driven by an electrical motor. A seal section operably connects between the motor and the pump for reducing a pressure differential between motor oil in the motor and well fluid surrounding the pump assembly. The pump assembly contains a sealed fluid. A sensor mounted to the well pump assembly detects contamination of the sealed fluid by well fluid encroaching into contact with the sealed fluid. The sensor may be mounted in the motor or the seal section to detect well fluid contamination of motor oil. The sensor may be mounted in a secondary pump that has that has temporary barriers to block the entry of well fluid into a buffer fluid contained in the secondary pump while the secondary pump is in a storage condition within a well. | 2014-04-10 |
20140099212 | AUTOMATIC OIL SPLILL DETECTION SYSTEM - A method for detecting and isolation a leak in a hydraulic system having a supply pump serving at least one control valve is disclosed. In one embodiment, the control valve has multiple work sections. In step of the method, the hydraulic system is activated. In another step, an actuation command for at least one of the work sections is received, for example from a human-to-machine interface. Subsequently, the method may include generating a flow demand for the work sections for which an actuation command has been received. The method also includes the step of implementing at least one of a first, second, third, and fourth leak detection and isolation protocol to detect and isolate a leak between the pump and the control valve assembly, a leak between the reservoir and the control valve assembly and a leak between the at least one work circuit and the control valve assembly. | 2014-04-10 |
20140099213 | IRRIGATION PUMP CONTROLLER SYSTEM AND METHOD OF USE - Disclosed herein is an invention directed to a system and method of use directed to a pivot irrigation control system utilizing cellular short messaging service (SMS) to communicate between the various elements of the system to provide status updates and controls of the elements within the system. In one embodiment, the pivot irrigation control system is comprised of a well controller element, at least one pump controller element, and an input/output element. The well controller element is communicatively coupled with the pump controller element(s) and the input/output element. In another embodiment, the controller element, the pump controller element(s), and the input/output element are all communicatively coupled with each other for the purpose of relaying the status of each element. In one embodiment the communicatively coupling is achieved through SMS communications between the elements. | 2014-04-10 |
20140099214 | CAPACITY CONTROL VALVE - In a capacity control valve, a discharged-fluid-receiving part having a diameter that is larger than the diameter of a valve hole interconnecting a first valve chamber and a third valve chamber is provided to the outer periphery section of a third valve part. It is thereby possible to obtain a capacity control valve in which, when the first valve part opens, the discharged-fluid-receiving part receives the pressure of the discharged fluid, the actuation response of the valve body during an opening action is moderated, an excessive increase in the sensitivity to a rise in pressure in the crank chamber caused by a rapid increase in the amount of coolant flowing into the crank chamber is prevented, and the action of the valve body is stable. | 2014-04-10 |
20140099215 | HIGH PRESSURE FUEL SUPPLY PUMP WITH ELECTROMAGNETIC SUCTION VALVE - To reduce collision noise created by the operation of an electromagnetic suction valve provided on a high pressure fuel supply pump. In the present invention, in order to achieve the above object, the mass of a member which collides by magnetic attractive force is reduced to reduce the noise to be generated. The thus configured present invention provides the following advantageous effects. The noise generated when a core and an anchor collide with each other by magnetic attractive force depends on the magnitude of the kinetic energy of a moving element. The kinetic energy to be consumed in the collision is only the kinetic energy of the anchor. The kinetic energy of a rod, being absorbed by a spring, does not contribute to the noise; thus, the energy when the anchor and the core collide with each other can be reduced, whereby the noise to be created can be reduced. | 2014-04-10 |
20140099216 | FREE PISTON TYPE TORSION DRIVE COMPRESSOR - The invention relates to a free piston type compressor | 2014-04-10 |
20140099217 | FUEL PUMP ASSEMBLY AND METHOD OF MAKING SAME - A fuel pump assembly and method of making the same is disclosed. The fuel pump assembly includes a brushless direct current (BLDC) motor and a circuit board formed as a discrete component from the BLDC motor. The BLDC motor includes a stator with a plurality of windings. A screw, or some other fastener, extends through the circuit board and threadedly engages a portion of the BLDC motor. The screws serve the dual functions of attaching the circuit board to the BLDC motor and electrically connecting the BLDC motor to the circuit board to power the BLDC motor. | 2014-04-10 |
20140099218 | ROTARY COMPRESSOR - A rotary compressor | 2014-04-10 |
20140099219 | ELECTROMAGNETIC PUMP - An electromagnetic pump including a piston, an electromagnetic portion that moves the piston forward, and a spring that moves the piston backward. The piston including a discharge check valve built in the piston. The piston is formed with a hollow portion that opens in an inner peripheral portion of an end surface of the piston, and a spring receiving surface formed on an outer peripheral portion of the end surface to receive the spring. The discharge check valve is fixed through plastic deformation of the piston by inserting the discharge check valve into the hollow portion from an opening of the piston, and partially pressing a portion of the spring receiving surface of the piston on an inner peripheral side after the insertion to recess the spring receiving surface and elevate an inner peripheral surface of the piston surrounding the hollow portion. | 2014-04-10 |
20140099220 | ELECTROMAGNETIC PUMP - An electromagnetic pump configured with an electromagnetic portion that generates an electromagnetic force for pressing the piston, and an urging member that urges the piston in a direction opposite to the electromagnetic force. A strainer member including a disk-shaped portion which has a disk shape and in which a strainer surface is formed, and a side portion that extends from an outer peripheral edge of the disk-shaped portion. A suction check valve being capable of sucking the working fluid via the strainer surface. The piston, the urging member, the suction check valve, and the strainer member are sequentially inserted into the cylinder from a side opposite to the electromagnetic portion, and the cover member is attached so as to press the strainer surface. | 2014-04-10 |
20140099221 | FUEL PUMP - A fuel pump has a motor portion and a pump portion, wherein fuel is sucked from an inlet port into the pump portion when an impeller is rotated and the pressurized fuel is discharged out of the fuel pump from an outlet port. A stator has multiple stator cores on which respective stator coils are wound to form a star-connection winding. A terminal sub-assembly is provided hi an axial side portion of the stator. The terminal sub-assembly has multiple conductive members and each end portion of the stator coils is respectively connected to connecting portions of the conductive members, which are arranged at equal intervals in a circumferential direction of the terminal sub-assembly. | 2014-04-10 |
20140099222 | HIGHLY AIRTIGHT GAS PUMP - A gas pump is composed of a gas suction member and a gas exhaust member. The gas suction member includes a gasbag having a hollow retractable portion being drivable by a motor for oppression or expansion, an intake valve allowing the air to pass therethrough when the hollow retractable portion is oppressed, and a flexible tube having two crosscuts, by which the flexible tube is divided into two vent valvular pieces. Each of the vent valvular pieces has a reinforcing strip formed on an internal wall thereof for forcing each of the vent valvular pieces to seal the exhaust passage. The gas exhaust member is mounted to the gasbag and includes a venthole and a guide slot. The venthole can receive the flexible tube therein. The guide slot communicates the hollow retractable portion and the intake valve for guiding the air into the hollow retractable portion. | 2014-04-10 |
20140099223 | COLD START VALVE AND HYDRAULIC ARRANGEMENT HAVING A COLD START VALVE OF THIS TYPE - A cold start valve for a hydraulic circuit has a valve slide with two counteracting control faces. It is possible to load a first control face with a control pressure and to load a second control face with a feed pressure. In addition, the first control face is loaded with the spring force of a valve spring. A damping space is configured to damp a stroke movement of the valve slide. The damping space is delimited by a damping face formed on the valve slide and oriented in accordance with the first control face. The damping face is configured to be loaded via the damping space with a damping pressure to damp the stroke movement. The damping space is connected in a throttled manner to a pressure space. The second control face of the valve slide is configured to be loaded with the feed pressure via the pressure space. | 2014-04-10 |
20140099224 | VARIABLE VOLUME BORE PISTON PUMP - A piston pump which permits advantageous operation over both short stroke piston movement and long stroke piston movement. | 2014-04-10 |
20140099225 | PUMP - The invention provides a pump comprising a pump inlet, a pump outlet, at least two threaded rotors and a pressure controlled valve, the pressure controlled valve being capable of controlling re-circulation of fluid from the pump outlet to the pump inlet. The pressure controlled valve can be a control valve. The invention also provides a multiple stage pump assembly comprising at least two pumps arranged in series, wherein at least one of the pumps is the aforementioned pump. | 2014-04-10 |
20140099226 | SIMPLIFIED ROOTS-TYPE BLOWER - The present disclosure relates to a simplified roots-type blower having an improved sound signature. The roots-type blower includes a rotor bore housing having a molded, one-piece polymeric construction. The rotor bore housing defines a first rotor bore and a second rotor bore. The rotor bore housing also defines a first bearing pocket corresponding to the first rotor bore and a bearing pocket corresponding to the second rotor bore axis. The rotor bore housing further defining a timing gear chamber. | 2014-04-10 |
20140099227 | PUMP APPARATUS - A pump apparatus includes: a housing; a pump unit; a suction passage; a discharge passage member including a discharge hydraulic passage which is formed therein, and which is arranged to discharge the hydraulic fluid pressurized by the pump unit to an outside of the housing; a first discharge passage insertion hole which is formed in the pump unit, and into which the discharge passage member is inserted through an elastic member; a second discharge passage insertion hole which is formed in the housing, and into which the discharge passage member is inserted through an elastic member; and an axial position adjusting mechanism arranged to adjust an axial position of the discharge passage member within the first discharge passage insertion hole and the second discharge passage insertion hole. | 2014-04-10 |
20140099228 | STEEL WITH EXCELLENT ROLLING-CONTACT FATIGUE PROPERTIES - Disclosed is a steel having high manufacturability and better rolling-contact fatigue properties. The steel contains C of 0.65% to 1.30%, Si of 0.05% to 1.00%, Mn of 0.1% to 2.00%, P of greater than 0% to 0.050%, S of greater than 0% to 0.050%, Cr of 0.15% to 2.00%, Al of 0.010% to 0.100%, N of greater than 0% to 0.025%, Ti of greater than 0% to 0.015%, and O of greater than 0% to 0.0025% and further contains iron and unavoidable impurities. Al-containing nitrogen compound particles dispersed in the steel have an average equivalent circle diameter of 25 to 200 nm, and Al-containing nitrogen compound particles each having an equivalent circle diameter of 25 to 200 nm are present in a number density of 1.1 to 6.0 per square micrometer. | 2014-04-10 |
20140099229 | NEGATIVE ELECTRODE ACTIVE MATERIAL FOR ELECTRIC DEVICE - A negative electrode active material for an electric device includes an alloy containing Si in a range of greater than or equal to 27% by mass and less than 100% by mass, Sn in a range of greater than 0% by mass and less than or equal to 73% by mass, V in a range of greater than 0% by mass and less than or equal to 73% by mass, and inevitable impurities as a residue. The negative electrode active material can be obtained with, for example, a multi DC magnetron sputtering apparatus by use of Si, Sn, and V as targets. An electric device using the negative electrode active material can achieve long cycle life and ensure a high capacity and cycle durability. | 2014-04-10 |
20140099230 | ALUMINUM ALLOY THAT IS NOT SENSITIVE TO QUENCHING, AS WELL AS METHOD FOR THE PRODUCTION OF A SEMI-FINISHED PRODUCT - An aluminum alloy that is not sensitive to quenching, for the production of high-strength forged pieces that are low in inherent tension, and high-strength extruded and rolled products, consisting of: 7.0-10.5 wt. % zinc, 1.0-2.5 wt. % magnesium, 0.1-1.15 wt. % copper, 0.06-0.25 wt. % zirconium, 0.02- 0.15 wt. % titanium, at most 0.5 wt. % manganese, at most 0.6 wt. % silver, at most 0.10 wt. % silicon, at most 0.10 wt. % iron, at most 0.04 wt. % chrome, and at least one element selected from the group consisting of: hafnium, scandium, strontium and/or vanadium with a summary content of at most 1.0 wt. %. The alloy can also contain contaminants at proportions of at most 0.05 wt. % per element and a total proportion of at most 0.15 wt. %, wherein the remaining component includes aluminum. | 2014-04-10 |
20140099231 | ELECTRIC WIRE OR CABLE - There is provided an aluminum-alloy material having sufficient electric conductivity and tensile strength as a wiring material and excellent in wire-drawing property, and an electric wire or cable using the same. An electric wire or cable includes an aluminum-alloy strand formed of an aluminum-alloy including Fe: 0.1% by mass or more to less than 1.0% by mass, Zr: 0 to 0.08% by mass, Si: 0.02 to 2.8% by mass, at least one of Cu: 0.05 to 0.63% by mass and Mg: 0.04 to 0.45% by mass, and the remainder being aluminum and unavoidable impurities. | 2014-04-10 |
20140099232 | SHEET OF SEMICONDUCTING MATERIAL, SYSTEM FOR FORMING SAME, AND METHOD OF FORMING SAME - A method of forming a sheet of semiconductor material utilizes a system. The system comprises a first convex member extending along a first axis and capable of rotating about the first axis and a second convex member spaced from the first convex member and extending along a second axis and capable of rotating about the second axis. The first and second convex members define a nip gap therebetween. The method comprises applying a melt of the semiconductor material on an external surface of at least one of the first and second convex members to form a deposit on the external surface of at least one of the first and second convex members. The method further comprises rotating the first and second convex members in a direction opposite one another to allow for the deposit to pass through the nip gap, thereby forming the sheet of semiconductor material. | 2014-04-10 |
20140099233 | WASH MONITOR AND METHOD OF USE - The present disclosure provides a monitoring device comprising a test composition, a test element comprising a test portion to which the test composition is releasably adhered, a detection reagent, and a container comprising a first end with an opening and a second end opposite the first end. The test composition comprises a predetermined quantity of tracer analyte. The container is configured to receive the test portion and configured to be operationally coupled to an analytical instrument. The tracer analyte and the detection reagent each are capable of participating in one or more chemical reaction that results in the formation of a detectable product. A method of using the monitoring device to assess the efficacy of a washing process is also provided. | 2014-04-10 |
20140099234 | MEMS BASED FILTER AND CATALIZER - The present invention provides a filter for separating particles and/or catalyzer for particle reaction in a fluid. The device comprising array of passageways fabricated on a die wherein the passageway size is controlled by actuators. The passageway size is monitored and the actuators controlling the passageway size are activated conditionally upon the passageway size monitoring. Using movable actuators the passageway can achieve passageway size that is less then the fabrication minimal resolution. Proper locating, setting and/or activation of the actuators create passageways that can perform filtration of particles, trapping of particles and catalyzing particles reaction. | 2014-04-10 |
20140099235 | BLOOD PERFUSION SYSTEM - An extracorporeal blood perfusion system includes a disposable assembly and a control unit having a control interface region. The interface region includes pump assemblies for selective pumping of venous blood, arterial blood, cardioplegia solution, suctioned blood and blood removed from the left ventricle. Valve assemblies control the flow of fluids through the assembly and to/from the patient and sensors monitor various fluid parameters including temperature and pressure within the various fluid circuits. The user interface is a functional screen interface for effecting the operation of the control unit and valve assemblies. The screen interface may be a touch screen having objects that corresponds to the component interface region. The display may be selectively controlled to provide graphic depictions of disposable assembly components with corresponding narrative instructions. | 2014-04-10 |
20140099236 | MICROCHIP SOLUTION SENDING SYSTEM - A microchip solution sending system may include a flow passage assembly that is at least provided with a fine flow passage that is provided with a detection region including a formed reaction field to which an antibody that reacts with a specific antigen is fixed; and a micro pump that is connected to the flow passage assembly and that is configured to send a specimen material solution that includes the specific antigen in a reciprocating manner. The specimen material solution that has been sent may pass through the detection region in a repetitive manner in the case in which the micro pump sends the specimen material solution in a reciprocating manner, | 2014-04-10 |
20140099237 | BIOMEDICAL MONITORING SYSTEM COMBINING A MOBILE DEVICE - The present invention provides a biomedical monitoring system combining a mobile device. Signals can be transmitted between the sensing device and the mobile device via the audio interface by modulating and demodulating the audio signals or encoding and decoding the digital signals. Thereby, it can be applied extensively to mobile devices having audio jacks and thus bringing more convenience. In addition, because the mobile devices inherently have the functions of operational processes, transmission, storage, interface operations, result displaying, network connection, image extraction, and power supply, the required components in sensing devices can be simplified substantially and hence reducing the volume and the manufacturing cost. | 2014-04-10 |
20140099238 | Chiral Separation System - A system for separation of enantiomers includes a column packed with a stationary phase; a magnetic field generator generating a magnetic field, within which the column is placed, and the magnetic field interacts with the enantiomers as the enantiomers elute through the column with a mobile phase; and a control unit, in communication with the magnetic field generator and the column, to adjust the strength and direction of the magnetic field to separate the enantiomers. | 2014-04-10 |
20140099239 | Reduced sorbent utilization for circulating dry scrubbers - Circulating dry scrubbing (CDS) systems and methods utilizes a particle classification unit operation to separate unreacted sorbent (such as lime, limestone, or sodium-based sorbent) such that a reactive fraction of the cut stream may be selectively recovered to a flue gas scrubbing system. This reduces the amount of fresh sorbent that must be supplied for pollutant removal. | 2014-04-10 |
20140099240 | STIRRING DEVICES - An embodiment of the present disclosure provides a hand held pipette for aspirating and dispensing liquids including, a stirring device assembly, including a vibration inducing unit, a power source for the vibration inducing unit, and a control for the vibration inducing unit. | 2014-04-10 |
20140099241 | Novel Micropores and Methods of Making and Using Thereof - Disclosed herein are methods of making micropores of a desired height and/or width between two isotropic wet etched features in a substrate which comprises single-level isotropic wet etching the two features using an etchant and a mask distance that is less than 2× a set etch depth. Also disclosed herein are methods using the micropores and microfluidic devices comprising the micropores. | 2014-04-10 |
20140099242 | ALIQUOT CONTAINER - An aliquot container includes an opening and a main body section. The main body section communicates with an outside through the opening and includes a peripheral portion defining an inner space. The inner space is tapered in a direction opposite to the opening. | 2014-04-10 |
20140099243 | PHOTOSENSITIVE RESIN COMPOSITION FOR FORMING BIOCHIP, AND BIOCHIP - It is intended to obtain a photosensitive resin composition that is capable of forming a highly fine pattern with a high aspect ratio while attaining the high adhesion of the pattern to a substrate, having low autofluorescence, and being exceedingly suitable for producing a biochip that causes exceedingly low damage on cultured cells. The photosensitive resin composition for forming a biochip of the present invention contains: an epoxy compound (A1) of a particular structure having an oxycyclohexane skeleton having an epoxy group; an epoxy compound (A2) of a particular structure which is a polyvalent carboxylic acid derivative having an epoxidized cyclohexenyl group; a cationic photoinitiator (B); and a solvent (C). | 2014-04-10 |
20140099244 | SORBENTS FOR THE OXIDATION AND REMOVAL OF MERCURY - A promoted carbon and/or non-carbon base sorbent are described that are highly effective for the removal of mercury from flue gas streams. The promoted sorbent comprises a carbon and/or non-carbon base sorbent that has reacted with and contains forms of halogen and halides. Optional components may be added to increase and/or preserve reactivity and mercury capacity. These may be added directly with the base sorbent, or in-flight within a gas stream (air, flue gas, etc.), to enhance base sorbent performance and/or mercury capture. Mercury removal efficiencies obtained exceed conventional methods. The promoted sorbent can be regenerated and reused. Base sorbent treatment and preparation methods are also described. New methods for in-flight preparation, introduction, and control of the active base sorbent into the mercury contaminated gas stream are described. | 2014-04-10 |
20140099245 | PROCESS AND SYSTEM EMPLOYING PHASE-CHANGING ABSORBENTS AND MAGNETICALLY RESPONSIVE SORBENT PARTICLES FOR ON-BOARD RECOVERY OF CARBON DIOXIDE FROM MOBILE SOURCES - A method and system are described for the on-board treatment of a hydrocarbon-fueled internal combustion engine (ICE) exhaust gas stream to reduce CO | 2014-04-10 |
20140099246 | CATALYTIC CONVERTER APPARATUS - A catalytic converter apparatus for use in an exhaust system of an internal combustion engine includes a housing having a gas inlet and a gas outlet, and at least one catalytic substrate element disposed in the housing. The at least one substrate element is divided into a plurality of zones or sections, the zones at least partially separated from one another to inhibit heat flow. The zones can be at least partially separated with walls. The walls can include insulating material for reducing the mobility of heat radially outwardly. Each of the zones defines a generally separate flow passage connecting the inlet and outlet in fluid communication. The apparatus can heat more rapidly from a cold start compared with conventional catalytic converters. | 2014-04-10 |
20140099247 | METHOD FOR IN-DUCT UREA INJECTION FOR SELECTIVE CATALYTIC REDUCTION ON SMALL BOILERS AND COMBUSTION SOURCES - A method for reducing NOx emissions from a lean burn combustor equipped with a NOx reducing exhaust catalyst, includes at least the following steps: (i) generating a computer based model of the geometry of an exhaust system of the combustor; (ii) computing at least one of flue gas velocity profiles and mass flow stream lines for exhaust gas flow through the exhaust system; (iii) inputting injector data comprising at least droplet size and velocity; (iv) modeling droplet trajectories for a plurality of injector locations; (v) modeling at least one flow conditioning device in the exhaust system; and (vi) manipulating the computer based model until an injector location is identified that provides a predicted root mean square (RMS) of reagent at the face of the catalyst that is less than 15%. | 2014-04-10 |
20140099248 | Method for Urea Decomposition and Ammonia Feed to a Selective Catalytic Reduction System - A method of reducing NOx emissions from a lean burn combustion source employs an aqueous solution of reagent that is injected into a continuous decomposition duct at a rate of 0.2-10 gph with a flowing side stream of hot gas at a rate of 150-3000 scfm and a temperature of greater than 700° F. in the decomposition duct such that the aqueous reagent is converted to ammonia gas that is conveyed by the continuous decomposition duct to an ammonia injection grid that is placed in a primary exhaust stream from the combustion source upstream of a NOx reducing catalyst and NOx is reduced. | 2014-04-10 |
20140099249 | IONIC LIQUIDS BASED ON OXALIC ACID MONO ESTERS - Monosubstituted oxalic acid derivatives of the general formula (I) | 2014-04-10 |
20140099250 | DEVICE FOR RECOVERING SICL4 SLURRY AND METHOD FOR THE SAME - A device for recovering SiCl | 2014-04-10 |
20140099251 | Method for preparing of spinel lithium titanium oxide nanofiber for negative electrode of lithium secondary battery - Disclosed is a method of preparing spinel lithium titanium oxide nanofibers for a negative electrode of a lithium secondary battery, including (S1) mixing an organic material selected from the group consisting of polyvinylpyrrolidone, polymethylmethacrylate, polyethylene, polyethylene oxide and polyvinyl alcohol, a lithium precursor, and a titanium precursor with a solvent, thus preparing a mixture solution, (S2) electrospinning the mixture solution, thus preparing composite nanofibers, and (S3) heat-treating the composite nanofibers, thus removing the organic material. In the spinel lithium titanium oxide nanofibers for a negative electrode of a lithium secondary battery prepared using the method according to the present invention, the spinel lithium titanium oxide nanofibers can provide a large surface area per unit volume, thus increasing the contact area between the electrolyte and the conductor and decreasing the lithium ion diffusion distance, thereby greatly contributing to improving electronic conductivity and ionic conductivity. | 2014-04-10 |
20140099252 | System and method for supplying hydrogen and deuterium to lenr and e-cat based energy generating systems - An approach for supplying hydrogen and/or deuterium to LENR and E-Cat based energy generating systems includes receiving a source material that is rich in hydrogen and/or deuterium. A gaseous form of at least one of those elements is extracted from the source material via electrochemical dissociation, hydrocarbon recovery, or a suitable mechanical process. The gaseous form of the element is preferably filtered to remove water vapor and other impurities before being pressurized and supplied to the energy generating system. Advantages of the approach include enhanced safety and system portability due to elimination of a need for pressurized gas storage tanks. | 2014-04-10 |
20140099253 | METHOD AND APPARATUS FOR MAGNETIC TREAMENT OF FUEL AND FLUIDS FOR COMBUSTIION EFFICIENCY AND REDUCTION OF CARBON EMISSIONS - Magnetic treatment devices used in a system to enhance fuel combustion for the reduction of carbon emissions and to increase fuel efficiency. A series of uniquely constructed ferrous back plates with accompanying permanent homopolar magnetic assemblies are utilized to produce the aforementioned effect. The homopolar assemblies are field specific to the combustion fluid. | 2014-04-10 |
20140099254 | COMBINATION THERAPY FOR INDUCING IMMUNE RESPONSE TO DISEASE - The present invention concerns combinations of two or more agents for inducing an immune response to cancer or infectious disease. Agents may include leukocyte redirecting complexes, antibody-drug conjugates, interferons (preferably interferon-α), and/or checkpoint inhibitor antibodies. The leukocyte redirecting complexes have at least one binding site for a leukocyte antigen and at least one binding site for an antigen on a diseased cell or pathogen. Preferably, the complex is a DNL™ complex. More preferably, the complex comprises a bispecific antibody (bsAb). Most preferably, the bsAb is an anti-CD3×anti-CD19 bispecific antibody, although antibodies against other leukocyte antigens and/or disease-associated antigens may be used. The complex is capable of targeting effector T cells, NK cells, monocytes or neutrophils to induce leukocyte-mediated cytotoxicity of cells associated with cancer or infectious disease. The cytotoxic immune response is enhanced by co-administration of interferon, checkpoint inhibitor antibody and/or ADC. | 2014-04-10 |
20140099255 | POLYMER BASED RADIONUCLIDE CONTAINING PARTICULATE MATERIAL - The invention relates to a particulate material having a diameter in the range of from 5 to 200 microns comprising polymeric matrix and stably incorporated radionuclide, processes for its production and a method of radiation therapy utilising the particulate material. | 2014-04-10 |
20140099256 | RADIOACTIVE LUMINESCENT NANOPARTICLE COMPOSITIONS - An embodiment of the invention is directed to a composition comprising a luminescent noble metal nanoparticle, wherein the surface of the noble metal nanoparticle is coated with a ligand, and wherein the noble metal nanoparticle is about 2 nm to 5 nm in diameter and further wherein a portion of the noble metal is present as its radioactive isotope. In an embodiment of the invention, the radioactive isotope is present at a concentration of up to 2% w/w of the noble metal. | 2014-04-10 |
20140099257 | Androgen Suppression, Prostate-Specific Membrane Antigen and the Concept of Conditionally Enhanced Vulnerability - Anti-androgen therapies represent the cornerstone of prostate cancer (PC) treatment. Yet all PC patients ultimately fail efforts to rein in the androgen receptor (AR). This invention is based on the discovery that prostate-specific membrane antigen (PSMA), a highly PC-specific and clinically validated cell surface target, is AR-suppressed and up-regulated in PC as a result of hormonal manipulation. This up-regulation occurs in an unexpected timeframe and it occurs even in the castrate-resistant setting. As a result, hormonal therapy creates a state of conditionally enhanced vulnerability of PC to PSMA-targeted anti-cancer/cytotoxic agents that can be exploited by leveraging anti-AR therapy by the addition of PSMA-targeted agents. We demonstrate this conditionally enhanced vulnerability in a castrate-resistant animal model. The state of conditionally enhanced vulnerability may be relevant for other cancer targets and efforts to screen for them may improve other cancer therapies. | 2014-04-10 |
20140099258 | Camptothecin-Binding Moiety Conjugates - The invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a camptothecin as a therapeutic moiety, and further relates to processes for making and using the said conjugates. | 2014-04-10 |
20140099259 | TUMOR-SPECIFIC RECOGNITION MOLECULES - The invention relates to recognition molecules which are directed towards tumors and can be used in the diagnosis and therapy of tumor diseases. | 2014-04-10 |
20140099260 | Anti-CD79B Antibodies and Immunoconjugates and Methods of Use - The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same. | 2014-04-10 |
20140099261 | DISTINGUISHING BENIGN AND MALIGNANT INDETERMINATE THYROID LESIONS - The application describes methods for accurately evaluating whether thyroid test samples, especially indeterminate thyroid samples, are benign or malignant. | 2014-04-10 |
20140099262 | ISOTOPICALLY LABELED CDP-CHOLINE AND USES THEREOF - The present invention provides CDP-Choline (Citicoline) and any salt thereof comprising at least one isotopically labeled carbon atom directly bonded to at least one deuterium atom, a composition comprising said CDP-Choline, uses thereof, methods for diagnosing and evaluating a state, condition, or disease in a subject utilizing CDP-Choline of the invention and kits comprising CDP-Choline of the invention. | 2014-04-10 |
20140099263 | POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE - Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles. | 2014-04-10 |
20140099264 | MEANS AND METHODS FOR IN VIVO TESTING OF THERAPEUTIC ANTIBODIES - The present invention provides methods and means for identifying a cancer-patient disposed to respond favourably to a therapeutic antibody as well as methods for in vivo selecting a xenograft tumor model which is most qualified for preclinical testing of a therapeutic antibody. These methods apply near-infrared fluorescence imaging which is an excellent imaging technology because of its simplicity, fast scanning times and non-hazardous radiation. | 2014-04-10 |
20140099266 | MAGNETIC FLUID NANOSYSTEM - Targeting contrast agent for magnetic resonance imaging (MRI). In preferred embodiments, self-assembled polyelectrolytes coated superparamagnetic iron oxide contrast agent particles are provided, which are labeled with targeting moieties, afforded enhanced relaxivity, improved signal-to-noise and targeting ability. Accordingly, the invention relates to a stable targeting contrast nanosystem applicable for magnetic resonance imaging (MRI) having at least one nanoparticle polyelectrolyte polyanion; a targeting agent conjugated to the biopolymer; and a superparamagnetic ligand. In another embodiment the nanosystem according to the invention has at least two biocompatible and biodegradable nanoparticle polyelectrolyte biopolymer. Particularly, the superparamagnetic iron oxide particles are coated by a polyelectrolyte biopolymer and this system self-assembles with the other biopolymer to produce stable nanosystem for magnetic resonance imaging. Targeting moieties are conjugated to a biopolymer or to the self-assembled biopolymers to realize a targeted delivery of contrast agent. Methods for making these targeting MRI contrast agents are also provided. | 2014-04-10 |
20140099267 | NEAR INFRARED ABSORBERS - An ink formulation having a marking component and a reduced indium tin oxide (r-ITO) is disclosed. The r-ITO in powder form exhibits a lightness (L*), according to the 1976 CIE (L*, a*, b*) space, of not more than 50. | 2014-04-10 |
20140099268 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES - A method for treating hair loss in mammals uses compositions containing 2-decarboxy-2-phosphinico prostaglandin derivatives. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth. Compositions containing 2-decarboxy-2-phosphinico prostaglandin derivatives can also be used to lower intraocular pressure and treat bone disorders. | 2014-04-10 |
20140099269 | CHEWING GUM HAVING SUSTAINED RELEASE OF NICOTINE - The present invention relates to a chewing gum having a high Surface Area to Volume ratio (SAV ratio), wherein said chewing gum comprises a water insoluble gum base matrix, a water soluble bulk portion and nicotine, wherein the gum base matrix, nicotine and the bulk portion are mixed and extruded to form a final extruded chewing gum product having a SAV ratio above 0.7, and wherein sustained release of nicotine is facilitated by adding 0.1-10% of C8-C10 triglycerides by weight of the chewing gum. | 2014-04-10 |
20140099270 | Method of Use and Preparation of HSA Fusion Protein Composition for Skincare - The present invention provides a recombinant fusion protein which stimulates the rejuvenation and reactivation of skin and epidermal cells for improving skin appearance, smoothing wrinkles and freckles, and whitening skin. Particularly, the present invention provides various types of products for improving skin, which contain recombinant fusion protein of human serum albumin (HSA) with cytokine peptides (EGF, FGF, KGF, HGH, HGF, PDGF, GCSF, interferon, IL- | 2014-04-10 |
20140099271 | DENTAL COMPOSITIONS COMPRISING A FATTY MONO(METH)ACRYLATE - Presently described are dental compositions comprising one or more fatty mono(meth)acrylates, methods of use, dental articles, and methods of making dental compositions. It has been found that a relatively low concentration of a fatty mono(meth)acrylate can improve the handling characteristics of a dental composition by reducing the tendency of the composition to stick to a dental instrument and/or by reducing the tendency of a dental composition to string when being manipulated by a dental instrument. In one embodiment, a hardenable dental composition is described comprising a polymerizable resin composition comprising at least one multifunctional ethylenically unsaturated monomer; 0.2 to 10 wt-% of one or more fatty mono(meth)acrylate monomers; and at least 50 wt-% of inorganic oxide filler. | 2014-04-10 |
20140099272 | DENTAL CARE PRODUCTS COMPRISING CARBONATE-SUBSTITUTED FLUORO-HYDROXYAPATITE PARTICLES - A dental care product comprising carbonate-substituted fluoro-hydroxyapatite particles having the formula: Ca | 2014-04-10 |
20140099273 | TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS - Disclosed is a topical skin composition and corresponding methods for its use that includes an extract from | 2014-04-10 |
20140099274 | EXTRACTS OF DARLINGTONIA CALIFORNICA - The present invention relates to an extract from plant parts of | 2014-04-10 |
20140099275 | LIGHTWEIGHT STYLING AGENTS - A styling agent in a cosmetically acceptable carrier includes, based in each case on its weight: 0.01 to 3 wt % of at least one copolymer A as defined herein, and 0.05 to 10 wt %, by preference 0.1 to 7.5 wt %, more preferably 0.25 to 6 wt %, and in particular 0.5 to 5 wt % of at least one film-forming polymer, and 0.5 to 30 wt %, by preference 1 to 25 wt %, more preferably 2.5 to 20 wt %, and in particular 5 to 15 wt % of at least one wax having a melting point in a range from 40° C. to 90° C. The agent has a high degree of hold and a pleasant care-providing feel, and is not heavy. | 2014-04-10 |
20140099276 | Compositions Having Hase Rheology Modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 2014-04-10 |
20140099277 | BIODEGRADABLE POLYURETHANE/UREA COMPOSITIONS - The present invention relates to biocompatible, biodegradable polyurethane/urea polymeric compositions that are capable of in-vivo curing with low heat generation to form materials suitable for use in scaffolds in tissue engineering applications such as bone and cartilage repair. The polymers are desirably flowable and injectable and can support living biological components to aid in the healing process. They may be cured ex-vivo for invasive surgical repair methods, or alternatively utilized for relatively non-invasive surgical repair methods such as by arthroscope. The invention also relates to prepolymers useful in the preparation of the polymeric compositions, and to methods of treatment of damaged tissue using the polymers of the invention. | 2014-04-10 |
20140099278 | BIOCOMPATIBLE POLYCAPROLACTONE FUMARATE FORMULATIONS - A polycaprolactone fumarate polymer useful as a matrix material for a biocompatible scaffold for tissue engineering applications is disclosed. The polycaprolactone fumarate polymer can be prepared by reacting caprolactone with an alkane polyol to prepare a polycaprolactone precursor, and then reacting the polycaprolactone precursor with fumaric acid or a salt thereof to prepare the polycaprolactone fumarate polymer. The use of an alkane diol, such as 1,2-propanediol, provides a linear polycaprolactone diol precursor. The use of an alkane triol, such as glycerol, provides a branched polycaprolactone triol precursor. The biocompatible polycaprolactone fumarate formulation releases no diethylene glycol or other undesirable byproducts during degradation. | 2014-04-10 |
20140099279 | METAL ALLOYS FOR MEDICAL DEVICES - A medical device that is at least partially formed of a novel metal alloy, which novel metal alloy improves the physical properties of the medical device. | 2014-04-10 |
20140099280 | Novel Superactive IL-33 Fragments, and Uses Thereof - The present invention discloses novel active polypeptide fragments of human IL-33 corresponding to natural forms generated by the proteases of human neutrophils (cathepsin G, elastase 2, proteinase 3), as well as the use thereof as a drug, in particular for the treatment of infectious diseases, inflammatory diseases, atherosclerosis, cardiovascular diseases, obesity, or cancer. | 2014-04-10 |
20140099281 | METHODS OF TREATMENT USING AN AMINOSTEROL COMPOSITION - This invention relates to stable aminosterol phosphate compositions. The aminosterol phosphate compositions permit administration without associated tissue damage and achieve a sustained release effect. | 2014-04-10 |
20140099282 | MODULATING INNATE IMMUNE CELL ACTIVITY BY LUNASIN AND SELECTED CYTOKINES - This disclosure provides compositions and methods for enhancing innate immune system activities and responses by combining lunasin with at least one cytokine. The compositions synergistically enhance the effect of these selected cytokine(s), including but not limited to, activating NK cells, augmenting NK's cytotoxicity against vinises and tumors, regulating NK-mediated anti-allergic inflammation, producing potent NK cells for cellular therapy using adoptive transfer, and facilitating dendritic cells antigen presentation. | 2014-04-10 |
20140099283 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2′-chloro nucleosides according to Formula 2001: | 2014-04-10 |
20140099284 | MODULATION NEURAL PATHWAYS - Provided herein are compositions and methods for the design of synthetic regulatory sequences and for subsequent modulation of neural pathways. | 2014-04-10 |
20140099285 | COMPOSITION FOR PREVENTING OR TREATING AIDS CONTAINING PLANT STEM CELL LINE DERIVED FROM CAMBIUM OF PANAX GINSENG INCLUDING WILD GINSENG OR GINSENG AS ACTIVE INGREDIENT - The present invention relates to a composition for preventing or treating acquired immunodeficiency syndrome (AIDS), comprising one or more of the following: a homogenous cell line, and a lysate, an extract and a culture thereof as an active ingredient. The homogenous cell line, the lysate, the extract and the culture thereof, which are derived from a natural product, minimize adverse side effects of prior therapeutic agents and safe for the human body. Further, they effectively increase the count of T cells such as CD4+ T cells and decrease the number of HIVs, thereby preventing opportunistic infection, dysneuria, and neoplaia caused by immune incompetence, and ultimately the risk of death. Therefore, they are useful in preventing and treating AIDS, and relieving symptoms of AIDS. | 2014-04-10 |
20140099286 | CELL THERAPY FOR CHRONIC STROKE - A method of treating stroke in a patient who has undergone a stroke comprising administering at least 2 million suitable neuronal cells in at least one brain area involved in the stroke. The method comprises the step of using a twist drill or a burr to form a hole in the skull through which the cells could be administered. Exemplary cells are hNT neuronal cells, HCN-1 cells, fetal pig cells, neural crest cells, neural stem cells, or a combination thereof. Also disclosed herein is a pharmaceutical composition of 95% pure hNT neuronal cells, which composition further includes a vial containing PBS and human neuronal cells. This vial is provided in a container with liquid nitrogen, whereby the composition is frozen and maintained at −170° C. before use. Also disclosed are methods of improving speech, cognitive, sensory, and motor function in a person who has experienced brain damage which interferes with function by administering a sterile composition of a sufficient number of neuronal cells or neural stem cells to the damaged area. Also disclosed is a method of replacing central nervous cells lost to neurodegenerative disease, trauma, ischemia or poisoning. | 2014-04-10 |
20140099287 | PLASMA PROTEIN CONCENTRATE FOR CELL DELIVERY IN REGENERATIVE APPLICATIONS - The invention is directed to concentrating autologously-derived plasma, using the concentrated plasma fluid to dilute the patient's cells and applying the combination of concentrated fluid with cells at a site of pathology or mixing the combination of concentrated fluid with cells with a particulate material like a bone void filler prior to placing the mixture at a site of pathology. | 2014-04-10 |
20140099288 | METHODS AND DEVICES FOR OBTAINING AND PROVIDING COMBINATION CELL THERAPY - The invention is directed to a method for isolating stromal cells to form a therapeutic composition; and administering said therapeutic composition to the subject. A further embodiment of the invention is directed to therapeutic compositions comprising isolated stromal cells. | 2014-04-10 |
20140099289 | Tissue-Engineered Endothelial and Epithelial Implants Differentially and Synergistically Regulate Tissue Repair - Endothelial implants restore vascular homeostasis after injury without reconstituting vascular architecture. Endothelial cells line the vascular epithelium and underlying vasa vasorum precluding distinction between cellular controls. Unlike blood vessels, the airway epithelium is highly differentiated and distinct from endothelial cells that line the bronchial vasa allowing investigation of the differential control tissue engineered cells may provide in airways and blood vessels. Through airway injury and cell culture models, tissue engineered implants of the bronchial epithelium and endothelium were found to promote synergistic repair of the airway through biochemical regulation of the airway microenvironment. While epithelial cells modulate local tissue composition and reaction, endothelial cells preserve the epithelium; together their relative impact was enhanced suggesting both cell types act synergistically for airway repair. | 2014-04-10 |
20140099290 | ENDOTHELIAL SCAFFOLDS - Provided herein is an endothelial scaffold comprising, consisting of, or consisting essentially of decellularized corneal stroma. In some embodiments, the scaffold has cultured endothelial cells seeded thereon. Methods of treating a patient in need of corneal endothelial transplant are also provided, including implanting the scaffold as described herein onto a cornea of the patient (e.g., by deep keratectomy). | 2014-04-10 |
20140099291 | METHODS AND COMPOSITIONS FOR TREATMENT OF RETINAL DEGENERATION - Disclosed herein are methods and compositions for treating retinal degeneration, such as occurs in retinitis pigmentosa and age-related macular degeneration, using descendents of marrow adherent stem cells that have been engineered to express an exogenous Notch intracellular domain. | 2014-04-10 |
20140099292 | CD14+ Cell Compositions and Methods of Using Same - The present invention provides CD 14 | 2014-04-10 |
20140099293 | METHOD FOR EX-VIVO SEPARATION OF APOPTOTIC CHROMATIN FRAGMENTS FROM BLOOD OR PLASMA FOR PREVENTION AND TREATMENT OF DIVERSE HUMAN DISEASES - A method of prevention/treatment of pathological consequences of DNA damage triggered by incorporation of circulating apoptotic chromatin fragments into healthy cells of individuals/patients in need therefore, said method comprising ex vivo or extra corporeal treatment of blood/plasma for removal of circulating chromatin fragments released from apoptotic cells which apoptotic chromatin fragments are capable of triggering DNA damage leading to genomic instability, senescence, apoptosis and cancerous transformation of healthy cells on being integrated into their genomes | 2014-04-10 |
20140099294 | Biotherapy for Pain - The present invention is directed to analgesic Clostridial neurotoxin derivatives comprising polypeptides having a long-lasting SNARE protein-selective endopeptidase activity. These derivatives selectively bind to and are internalized by non-neuronal cells secreting cytokines or sensory neurons in preference to motor neurons or autonomic neurons. The invention is also directed to nucleic acid constructs encoding such polypeptides, and methods of making such derivatives and nucleic acid constructs, and methods of treating pain, such as chronic pain, by administering such derivatives to a patient suffering from, or at risk of suffering from such pain. | 2014-04-10 |
20140099295 | Methods of Treating Glucose Metabolism Disorders - Compositions and methods for modulating levels of PLA2G12A are provided. Methods for treating various conditions, such as conditions that are associated with or that result in reduced muscle function and/or muscle mass, are provided. Methods for modulating glucose and/or insulin levels in glucose metabolism disorders are provided. | 2014-04-10 |
20140099296 | TOPICALLY OR ORALLY APPLIED ALOE, DISTILLED WATER, SODIUM CHLORIDE, AND LYSOZYME MIXTURE AND METHOD OF PRODUCING THE MIXTURE - A skin and/or oral treatment mixture for treating tattooed or pierced skin such as that resulting from a body piercing, oral piercing, or tattoo procedure includes non-iodized sodium chloride, distilled water, | 2014-04-10 |
20140099297 | ACE2 POLYPEPTIDE - The present invention relates to recombinant ACE2 polypeptide, where the ACE2 polypeptide is present as a dimer. The dimer is formed specifically from glycosylated monomers and is used for producing pharmaceutical products with an extended half-life | 2014-04-10 |
20140099298 | Botulinum toxin treatments of Depression - Methods for preventing or treating depression including a depression mediated by the thalamus. Depression, including a thalamically mediated depression, can be treated by peripheral administration of a botulinum toxin to or to the vicinity of a trigeminal sensory nerve, thereby preventing or treating the depression. | 2014-04-10 |
20140099299 | Methods and Compositions for Cytomegalovirus IL-10 Protein - The present invention provides methods and compositions for treating and/or preventing a cytomegalovirus infection in a subject, comprising administering to the subject an effective amount of a cytomegalovirus IL-10 protein modified to have reduced functional activity while retaining immunogenicity. The present invention further provides nucleic acid molecules encoding a cytomegalovirus IL-10 protein or fragment thereof of this invention as well as vectors comprising such nucleic acids. Also provided herein are neutralizing antibodies that specifically bind cmvIL-10. | 2014-04-10 |
20140099300 | METHODS FOR PREDICTING AND IMPROVING THE SURVIVAL OF GASTRIC CANCER PATIENTS - The present invention provides assays and methods for predicting the post-operative survival of a subject having an early stage gastric cancer after tumor surgery. The present invention also provides methods for treating a subject having an early stage gastric cancer by administering a combination therapy tailored to the signal transduction biomarkers that are activated in the cancer. In particular embodiments, the methods of the invention rely on the detection of the activation state or level of a specific combination of signal transducer analytes in a cancer cell obtained from the subject. Thus, the methods of the invention are particularly useful for predicting the survival or prognosis of a subject having an early stage gastric cancer and for guiding both pre- and post-operative treatment decisions by identifying subjects who would benefit from combination therapy as opposed to monotherapy. | 2014-04-10 |
20140099301 | ANTIBODY FORMULATION - The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation. | 2014-04-10 |