12th week of 2014 patent applcation highlights part 45 |
Patent application number | Title | Published |
20140080044 | Imaging Particulates, Paper and Process, and Imaging of Paper Using Dual Wavelength Light - The present invention provides dual wavelength imaging compositions, processes for forming dual wavelength imaging compositions, methods for forming images using dual wavelength imaging compositions and substrate (e.g., paper web) treated (e.g., coated) on one or both sides with dual wavelength imaging compositions. Also provided is a dual wavelength imaging particulate comprising a matrix of polymer material and containing: one or more image-forming agents; a photo-oxidizing agent which is activated at a first wavelength of light to cause the one or more image-forming agents to form one or more images; and a reducing agent which is activated at a second wavelength of light to cause termination of the formation of the one or more images. | 2014-03-20 |
20140080045 | METHOD OF PREPARING DEVELOPER, DEVELOPER FOR ELECTROPHOTOGRAPHY, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS - A method of preparing a developer includes mixing a carrier and a powder with each other while falling with gravity. | 2014-03-20 |
20140080046 | TONER FOR FORMING ELECTROSTATIC IMAGE, DEVELOPER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS - To provide a toner, which contains a colorant, a binder resin, and a releasing agent, wherein the toner satisfies the following (a) to (c); (a) the toner contains at least a polyester resin as the binder resin; (b) the toner has Tg1st of 25° C. to 50° C.; and (c) the toner has a TMA compressive deformation rate (TMA %) of 10% or lower at 50° C. under a condition having relative humidity of 70%, wherein the Tg1st is glass transition temperature of the toner for first heating, as the toner is measured by a DSC system (a differential scanning calorimeter). | 2014-03-20 |
20140080047 | ELECTROPHOTOGRAPHIC TONER, TWO-COMPONENT DEVELOPER CONTAINING TONER, AND IMAGE FORMING APPARATUS - To provide an electrophotographic toner, which contains a crystalline resin, a non-crystalline resin, a colorant, and a releasing agent, wherein the toner has a storage elastic modulus of 5.0×10 | 2014-03-20 |
20140080048 | TONER AND METHOD FOR PRODUCING TONER - A toner is provided that can maintain high transferability even in long-term image output, can maintain high chargeability even in a high temperature and high humidity environment, and rarely causes fogging due to charging failure. The toner contains toner particles produced by a suspension polymerization method or a dissolution suspension method. The volume-average particle diameter (Dv) of silica particles is 50 nm or more and 800 nm or less. The mass loss rate due to heating of the silica particles from 105° C. to 200° C. is 0.60% or less. The hydrophobicity of the silica particles is 5% or more and less than 40%. | 2014-03-20 |
20140080049 | YELLOW TONER - To provide a yellow toner having a colorant in a good dispersed state, obtained through excellent granulation performance and having stable developing performance, the yellow toner contains a binder resin, a wax and a colorant, and is characterized by containing as the colorant a compound represented by the following general formula (1) and a compound represented by the following general formula (2). | 2014-03-20 |
20140080050 | TONER, DEVELOPMENT AGENT, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD - Toner contains a binder resin, wherein the binder resin contains a block copolymer A containing a crystalline segment X and a non-crystalline segment Y, wherein the toner has a thermo-mechanical analysis (TMA) compressive deformation amount (TMA %) of 10% or less at 50° C. and a relative humidity of 90%, wherein the toner has a spin-spin relaxation time (t130) of 10 ms or greater at 130° C. as measured by pulse nuclear magnetic resonance (NMR), wherein the toner has a spin-spin relaxation time (t′70) of 1 ms or less at 70° C. as measured by pulse NMR when descending from 130° C. to 70° C. | 2014-03-20 |
20140080051 | TONER AND METHOD FOR PRODUCING TONER - To provide a toner (X), which contains toner particles, each toner particle contains: a core phase (Q) containing a crystalline resin (A); and a shell phase (S) provided on a surface of the core phase (Q), where the shell phase (S) contains a crystalline polyurethane resin (B), wherein maximum peak temperature (Ta) of heat of melting of the crystalline resin (A) is 40° C. to 70° C., and maximum peak temperature (Tu) of heat of melting of the crystalline polyurethane resin (B) is 50° C. to 90° C. | 2014-03-20 |
20140080052 | CARRIER FOR TWO-COMPONENT DEVELOPER, ELECTROSTATIC LATENT IMAGE DEVELOPER, AND IMAGE FORMING METHOD - A carrier for developing electrostatic latent images produced in an image developer includes a magnetic particulate core material and a covering layer covering the surface of the core material. The image developer includes an image bearer, a developer bearer including comprising a magnetic field generator inside and a developer regulation member facing the surface of the image developer with a predetermined gap. The carrier has a bulk density of from 1.6 to 2.25 g/cm | 2014-03-20 |
20140080053 | ELECTROSTATIC-IMAGE DEVELOPING TONER, ELECTROSTATIC IMAGE DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE-FORMING APPARATUS, AND METHOD FOR FORMING IMAGE - An electrostatic-image developing toner contains a polyester resin prepared by addition reaction of a polycondensate of a carboxylic acid component and an alcohol component with an isocyanate-containing compound. The polycondensate has an active hydrogen group. The alcohol component includes a rosin diol represented by general formula (1): | 2014-03-20 |
20140080054 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF - A lithographic printing plate precursor which is excellent in both the on-press development property and the printing durability and which is excellent particularly in the on-press development property after preservation for a long period of time, wherein the lithographic printing plate precursor includes an intermediate layer containing a polymer compound including a repeating unit (a1) having a support-adsorbing group and a repeating unit (a2) having a polyoxyalkylene group having a repeating number of oxyalkylene units from 8 to 120 between a support and a polymerizable image-recording layer, and contains a compound having a molecular weight of 1,500 or less and having an oxyalkylene group in at least any of the intermediate layer and the polymerizable image-recording layer. | 2014-03-20 |
20140080055 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS - A chemically amplified resist composition comprising a base polymer and an amine quencher in the form of a β-alanine, γ-aminobutyric acid, 5-aminovaleric acid, 6-aminocaproic acid, 7-aminoheptanoic acid. 8-aminooctanoic acid or 9-aminononanoic acid derivative having an unsubstituted carboxyl group has a high contrast of alkaline dissolution in rate before and after exposure and forms a pattern of good profile at a high resolution, minimal roughness and wide DOF. | 2014-03-20 |
20140080056 | ONIUM COMPOUNDS AND METHODS OF SYNTHESIS THEREOF - New onium salt compounds and methods for synthesis of such compounds are provided. Preferred methods of the invention include (a) providing an onium salt compound comprising a sulfonate component having an electron withdrawing group; and (b) treating the onium salt compound with a halide salt to form a distinct salt of the onium compound. The present onium compounds are useful as an acid generator component of a photoresist composition. | 2014-03-20 |
20140080057 | Composition, process of preparation and method of application and exposure for light imaging paper - The present invention provides dual energy imaging compositions, processes for forming dual energy imaging compositions, methods for forming images using dual energy imaging compositions and substrate (e.g., paper web) treated (e.g., coated) on one or both sides with a dual energy imaging composition. Also provided is a particulate comprising a matrix of polymer material and containing one or more image-forming agents and a photo-oxidizing agent useful in making dual energy imaging compositions. | 2014-03-20 |
20140080058 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME - Acid generator compounds are provided that are particularly useful as photoresist composition components. Preferred acid generators include cyclic sulfonium compounds that comprise a covalently linked acid-labile group. | 2014-03-20 |
20140080059 | ACID GENERATOR COMPOUNDS AND PHOTORESISTS COMPRISING SAME - Acid generator compounds are provided that are particularly useful as a photoresist composition component. Acid generator compounds of the invention comprise 1) a cyclic sulfonium salt and 2) a covalently linked photoacid-labile group. In one aspect, thioxanthone acid generator compounds are particularly preferred, including acid generator compounds that comprise (i) a thioxanthone moiety; and (ii) one or more covalently linked acid labile-groups. | 2014-03-20 |
20140080060 | ACID GENERATOR COMPOUNDS AND PHOTORESISTS COMPRISING SAME - Acid generator compounds are provided that are particularly useful as a photoresist composition component. In one preferred aspect, cyclic sulfonium salt and photoresist compositions that comprise such compounds are provided. In another preferred aspect, acid generator compounds are provided that comprise one or more covalently linked acid-labile moieties, particularly ester-containing acid-labile moieties. | 2014-03-20 |
20140080061 | PHOTORESISTS CONTAINING POLYMER-TETHERED NANOPARTICLES - Compositions such as photoresists and microfabrication processes are provided that can produce high-fidelity microfabricated structures. The provided photoresists can have reduced swelling during the development phase and can give tight tolerances for products, such as microneedles, that can be used, for example, in the medical field. The provided compositions include a photoresist, a photoinitiator system dispersed in the photoresist, and a polymer-tethered nanoparticle dispersed in the photoresist. The photoresist can be a negative photoresist and the photoinitiator system can include a two-photoinitiator system. The polymer-tethered nanoparticle can include an acrylic polymer and, in some embodiments, can include poly(methyl methacrylate). The nanoparticles can include silica. | 2014-03-20 |
20140080062 | PHOTORESISTS COMPRISING MULTIPLE ACID GENERATOR COMPOUNDS - The present invention relates to new photoresist compositions that comprise (a) a polymer comprising an acid generator bonded thereto; and (b) an acid generator compound that is not bonded to the polymer and that comprises one or more acid-labile groups. | 2014-03-20 |
20140080063 | PIGMENT DISPERSION, INK COMPOSITION INCLUDING PIGMENT DISPERSION, AND COLOR FILTER YELLOW RESIST COMPOSITION INCLUDING PIGMENT DISPERSION - The present invention provides a pigment dispersion excellent in dispersibility. Furthermore, the present invention provides a color filter yellow resist composition and an ink composition, which include the pigment dispersion. A pigment dispersion containing at least a compound represented by General formula (1) and a yellow pigment represented by General formula (2) in a dispersion medium and a method for manufacturing the same are provided. Furthermore, a color filter yellow resist composition and an ink composition are provided, wherein images can be displayed with high spectral characteristics and high display contrast because the brightness is high and the hue of yellow is excellent. | 2014-03-20 |
20140080064 | RESIST PROTECTIVE FILM-FORMING COMPOSITION AND PATTERNING PROCESS - A pattern is printed by forming a photoresist layer on a wafer, forming a protective film thereon, exposure, and development. The protective film is formed from a composition comprising a copolymer comprising recurring units derived from a styrene, indene, benzofuran or benzothiophene monomer having 1,1,1,3,3,3-hexafluoro-2-propanol, and recurring units derived from a styrene, vinylnaphthalene, indene, benzofuran, benzothiophene, stilbene, styrylnaphthalene or dinaphthylethylene monomer and an ether solvent. | 2014-03-20 |
20140080065 | METHOD OF LITHOGRAPHY - A lithography method of manufacturing integrated circuits is disclosed. A combination photoalignment-photoresist layer is formed on a substrate. A treatment is performed on the combination photoalignment-photoresist layer. The combination photoalignment-photoresist layer is exposed to a predetermined pattern. The combination photoalignment-photoresist layer is developed to form a pattern and expose a portion of the substrate. | 2014-03-20 |
20140080066 | DOUBLE PATTERNING METHOD - A double patterning method includes providing a first resist film on a substrate using a first photoresist composition. The first resist film is exposed. The exposed first resist film is developed using a first developer to form a first resist pattern. A second resist film is provided in at least space areas of the first resist pattern using a second photoresist composition. The second resist film is exposed. The exposed second resist film is developed using a second developer that includes an organic solvent to form a second resist pattern. The first resist pattern is insoluble or scarcely soluble in the second developer. | 2014-03-20 |
20140080067 | METHOD OF SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION - A method of fabricating a semiconductor integrated circuit (IC) is disclosed. The method includes providing a substrate having two different topography areas adjacent to each other. A step-forming material (SFM) is deposited over the substrate. A patterned SFM is formed in the low topography area of the two areas. The formation of the patterned SFM provides a fairly planar surface across over the substrate. | 2014-03-20 |
20140080068 | METHOD OF FORMING PATTERNS - A method of forming patterns includes (a) coating a substrate with a resist composition for negative development to form a resist film, wherein the resist composition contains a resin capable of increasing the polarity by the action of the acid and becomes more soluble in a positive developer and less soluble in a negative developer upon irradiation with an actinic ray or radiation, (b) forming a protective film on the resist film with a protective film composition after forming the resist film and before exposing the resist film, (c) exposing the resist film via an immersion medium, and (d) performing development with a negative developer. | 2014-03-20 |
20140080069 | DOUBLE PATTERNING BY PTD AND NTD PROCESS - A method of manufacturing using a double patterning method is provided. The double patterning method uses a first developer and a second developer that are different. For example, the first developer may be a positive tone developer for a positive photoresist while the second developer may be a negative tone developer for the positive photoresist. Photoresists having a photoactive compound are also provided that may be useful in double patterning methods. | 2014-03-20 |
20140080070 | CLOSE-COUPLED STEP-UP VOLTAGE CONVERTER AND ELECTRODE FOR A COMBUSTION SYSTEM - A high voltage signal is output to an electrode, which applies electrical energy to a combustion reaction. The high voltage signal can be output by a step-up voltage converter to the electrode via a close electrical coupling. The close electrical coupling is configured to electrically isolate the high voltage signal from a human-accessible volume. | 2014-03-20 |
20140080071 | METHOD AND DEVICE FOR CLEANING AN INDUSTRIAL WASTE GAS COMPRISING CO2 - A gas treatment plant ( | 2014-03-20 |
20140080072 | METHOD AND APPARATUS FOR A DUAL MODE BURNER YIELDING LOW NOX EMISSION - A method of operating a burner includes providing supplying a combustible mixture containing a ratio of fuel and air that is incapable of maintaining a stable flame to a combustion chamber. The combustible mixture is ignited by an igniter, and presence of a flame is sensed. The igniter is maintained active to sustain combustion of the combustible mixture within the combustion chamber so that a space exterior to the combustion chamber is heated to a temperature at or above an auto-ignition temperature of the combustible mixture. The temperature of the space exterior is monitored and the combustible mixture is provided at a second flow rate, which is higher than the first flow rate, to extinguish the flame in the combustion chamber such that combustion occurs in the space exterior to the combustion chamber. When combustion occurs in the space exterior to the combustion chamber, the igniter is deactivated. | 2014-03-20 |
20140080073 | HIGH PRESSURE FOSSIL FUEL OXY-COMBUSTION SYSTEM WITH CARBON DIOXIDE CAPTURE FOR INTERFACE WITH AN ENERGY CONVERSION SYSTEM - A combustion system for operational connection to an energy conversion system and a method of providing thermal energy to the energy conversion system. The system comprises a combustor to be oxy-fired at above atmospheric pressure, using solid, liquid or gaseous fuels, with a supply of oxygen and supercritical carbon dioxide. The combustion gases from the combustor are delivered to a heat exchanger which interfaces with the energy conversion system. Temperatures in the combustor, and the delivery temperature to the heat exchanger, are controlled by selective recirculation of at least part of the combustion gases to the combustor, and by modulating the supply of oxygen and fuel to the combustor. Any combustion gases which are not recirculated are processed to separate carbon dioxide for use or sequestration. The system and method substantially eliminate emissions of carbon dioxide, while providing a highly efficient supply of thermal energy to the energy conversion system. | 2014-03-20 |
20140080074 | PREMIX GAS BURNER WITH TEMPERATURE MEASUREMENT - A premix gas burner comprises a burner deck which comprises a fiber based substrate and a perforated plate or a screen supporting the fiber based burner substrate. The premix gas burner further comprises at least two contact wires that are forming a thermocouple. The contact wires are directly or indirectly fixed to the burner deck to measure a temperature of the burner deck when the premix gas burner is in operation. The fiber based substrate is locally at least partly connected directly or indirectly to the perforated plate or the screen in the region where the contact wires of the thermocouple are directly or indirectly fixed to the burner deck. | 2014-03-20 |
20140080075 | BURNER CONTROL SYSTEM - A burner control system for improving burner performance and efficiency. The system may determine fuel and air channel or manifold parameters. Determination of parameters may be performed with a sensor connected across the air and fuel channels. A signal from the sensor may control the parameters which in turn affect the amounts of fuel and air to the burner via a controller. Parameter control of the fuel and air in their respective channels may result in more accurate fuel and air ratio control. One or more flow restrictors in fuel and/or air bypass channels may further improve accuracy of the fuel and air ratio. The channels may be interconnected with a pressure or flow divider. Byproducts of combustion in the exhaust, temperatures of gas and air, flame quality and/or other items may be monitored and adjusted with control of the fuel and air ratio for optimum combustion in the burner. | 2014-03-20 |
20140080076 | RELIABLE CARBON-NEUTRAL POWER GENERATION SYSTEM - Systems for providing reliable, controllable power without releasing the greenhouse gas carbon dioxide (CO | 2014-03-20 |
20140080077 | AUTOMOTIVE IGNITION COIL HAVING A CORE WITH AT LEAST ONE EMBEDDED PERMANENT MAGNET - In a spark plug ignition assembly for a spark plug, an ignition coil assembly has a steel laminated core, said core having a first core portion and a second core portion, and a primary winding around the first core portion and a secondary winding around the primary winding. A spark plug connecting member is provided for connecting the coil assembly to the spark plug. At least one of the first and second core portions has a slot therein with a magnet located in the slot. | 2014-03-20 |
20140080078 | Multi-Gas Appliance - Cooking appliance having an external control panel equipped with one or more regulating valves, where the rotary regulator organ is equipped with various peripheral openings for supplying a flow Q. For the supply of one or another type of gas, NG or LPG, either the control knob or a bezel disk in the external panel are interchangeable on the appliance, being chosen between two different available units, one and the other permitting two different angular position limits A2, A3 of the regulator organ or the supply of a constant flow Qmin through one or another opening with calibrated sections, respectively for NG or LP gas. An appendix in the control knob guided in a slide groove on the control panel of the appliance, or a tongue on the bezel disk stopping the rotation of the control knob, determines the travel limit A2 for the supply of Qmin of NG. | 2014-03-20 |
20140080079 | DEVICE FOR USE IN BURNER AND METHOD FOR MANUFACTURING THE SAME - A device for use in a burner, including a honeycomb body formed from a metal band. The metal band is laminated or coiled to yield a plurality of holes or apertures. The honeycomb body has first and second surfaces which are opposite to each other. The holes or apertures penetrate through the first surface and the second surface, and an outer boundary of the first surface and an outer boundary of the second surface are connected whereby yielding a lateral surface. A through hole is disposed on the lateral surface of the honeycomb body and penetrates inward through multiple layers of adjacent laminated or coiled metal bands, and a metal wire is disposed in the through hole; and/or, a part of the laminated or coiled metal bands on the first surface and/or the second surface are embedded, overlapped and engaged with adjacent metal bands to form an embedded member. | 2014-03-20 |
20140080080 | Annealed WVT Membranes to Impart Durability and Performance - A method for improving the chemical stability of a vapor transfer membrane includes providing a vapor transfer membrane including an ionomer layer having protogenic groups and then annealing the vapor transfer membrane at a temperature greater than about 100° C. Advantageously, the performance and durability of WVT membranes are markedly improved by thermally annealing the membranes. | 2014-03-20 |
20140080081 | HEAT EXCHANGERS IN SAPPHIRE PROCESSING - Systems and methods are presented for efficient heating during production of corundum. One embodiment takes the form of a system for processing corundum including a first furnace and a second furnace. The first and second furnaces are sequentially arranged and heat from the first furnace is subsequently used to heat the second furnace. | 2014-03-20 |
20140080082 | LIGHT CURE BITE PLATE FOR ORTHODONTIC REMODELING DEVICES - Improved customizable bite plates using curable resins, especially light curable resins, for use with orthodontic vibratory devices. | 2014-03-20 |
20140080083 | FUNCTIONAL DENTOFACIAL ORTHOPEDIC APPARATUS - The invention relates to a functional dentofacial orthopedic apparatus ( | 2014-03-20 |
20140080084 | CYCLIC INTERRUPTIVE FORCE ORTHODONTIC DEVICE AND SYSTEM - Provided herein is a cyclic interruptive force orthodontic device and a system comprising the same. Methods of making and using the same are also provided. | 2014-03-20 |
20140080085 | ARRANGEMENT INTRODUCED IN BRACKET WITH CURVILINEAR RIDGES - Arrangement introduced in bracket with curvilinear ridges comprises one bracket for fixed braces that belongs to the orthodontics and, unlike conventional brackets, has unique geometry with specific functionalities, such as a clip that detaches close to the basis and rounded edges. The bracket with curvilinear ridges comprises two pieces, the clip/lock, which encapsulates the traction wire, and main structure, which is monoblock and has rounded corners. The main structure has a squared basis topped by an upper-basis covering all the width and a central third of the depth, being its height proportional to width and depth. Above the upper-basis, a “U” structure is developed with a quadratic profile that has four hooks in its upper vertexes, with concave upper portion and convex bottom portion, being one of these hooks equipped, at the head and in material continuity, by a spherical hook preceded by a connection segment with rectangular flat profile. | 2014-03-20 |
20140080086 | Image Navigation Integrated Dental Implant System - An image navigation integrated dental implant system includes a control unit for storing and transmitting data streams, a scan module electrically connected to the control unit for scanning and taking the pictures of the soft tissue and hard tissue of the parenchyma of the oral cavity of a patient and the related external skin color and transmitting the obtained data to the control unit, a design module electrically connected to the control unit for receiving the oral cavity data from the control unit and using the data to design a oral cavity simulation diagram, and a navigator module electrically connected to the control unit for receiving the oral cavity data and photographing the oral cavity and then providing a picture to guide the dentist to perform the dental implant surgery. | 2014-03-20 |
20140080087 | LASER BASED COMPUTER CONTROLLED DENTAL PREPARATION SYSTEM - A dental tissue treatment apparatus and associated methods includes a feedback-controlled beam guidance system for directing treatment to a defined area of dental tissue. | 2014-03-20 |
20140080088 | DENTAL ARTICULATOR - Provided is a dental articulator, and more particularly, a dental articulator, in which a tray keeping a shape and dimensions of a dental model is fitted into an upper portion of a base member to which the dental model is coupled. Particularly, the tray coupled to a top surface of the base member is geometrically similar to the base member, and includes a boundary wall formed along an edge thereof at a predetermined thickness and height, a through-hole formed inside the boundary wall, and a pin cap structure that has a plurality of fitting holes into which pins of a pin structure of the base member are fitted and which are continuously formed along an inner central axis of the through-hole and that is connected to opposite inner ends of the boundary wall. Further, each of the arcuate and linear boundary walls of the tray has a plaster anti-overflow flange formed at an upper end thereof and bent in an outward direction to prevent plaster from overflowing down. The front arcuate boundary wall includes tool insertion cages in lower ends of both lateral surfaces thereof which are recessed inwards so that the dental model is easily separated from the base member after being hardened. | 2014-03-20 |
20140080089 | DEVICE AND METHOD OF MANUFACTURE THEREOF FOR CREATING A POSITIVE PRESSURE ENVIRONMENT FOR TREATMENT OF ORAL BIOFILMS ASSOCIATED WITH PERIODONTAL DISEASE - A medicament delivery tray and method for treating periodontal disease include fitting of a tray about the teeth and gums wherein the tray includes a seal that creates a substantially airtight seal against the gum line and a substantially airtight treatment chamber about the enclosed teeth and gums, the tray further having a reinforcing skirt providing a biasing force to the seal wherein a positive pressure can be created in the treatment chamber for forcing a medicament into the gums about the enclosed teeth. | 2014-03-20 |
20140080090 | DENTAL MICRO-TORNADO TISSUE CUTTING AND REMOVAL METHOD AND APPARATUS - A method and apparatus is disclosed for treating teeth associated with tooth structure removal and disinfection, in particular for endodontic procedures such as root canal tissue removal and decay treatment. Traditional methods involve the use of files, reamers, chemicals, drills, and burs, which have many disadvantages. The disclosed method and apparatus are based on the use of micro-tornado forces generated in a small working head attached to a dental hand piece and discharged from an extended cannula into a root canal orifice or a cavity to abrade, cut, and remove the content. | 2014-03-20 |
20140080091 | ALVEOLAR BONE AUGMENTATION KIT - An alveolar bone augmentation kit includes lateral and vertical augmentation sets. The lateral augmentation set is made of a bone graft material. The lateral augmentation set can be implanted in an alveolar bone. The vertical augmentation set includes two attachment units and an adjustment and lift unit. The first attachment unit includes a post and a first fastener. The post secured to the alveolar bone by the first fastener. The adjustment and lift unit includes a beam, an elevating rod movably connected to the beam, and a joint for rotationally connecting the beam to the post. The second attachment unit includes a plate and a second fastener. A first portion of the plate is placed against the elevating rod. The second fastener is driven in the alveolar bone via an opening in a second portion of the plate and an aperture in the lateral augmentation set. | 2014-03-20 |
20140080092 | TEMPORARY DENTAL PROSTHESIS FOR USE IN DEVELOPING FINAL DENTAL PROSTHESIS - A method of manufacturing a permanent prosthesis for attachment to a dental implant installed in a mouth of a patient includes scanning a patient specific temporary prosthesis (PSTP) to obtain scan data. The PSTP is attached to the dental implant in the mouth of the patient. Gingival tissue surrounding the PSTP is permitted to heal in the mouth of the patient. In response to aesthetics of the healed gingival tissue surrounding the PSTP in the mouth of the patient not being acceptable, the PSTP is physically modified by (i) removing material from the PSTP, (ii) adding material to the PSTP, or (iii) both. The modified PSTP is scanned and a permanent prosthesis is fabricated as a replica of the modified PSTP using scan data generated from the scan of the modified PSTP. | 2014-03-20 |
20140080093 | Customized Dental Prosthesis For Periodontal or Osseointegration, and Related System and Methods - Dental prosthesis, systems, and methods of forming and using a dental prosthesis, are provided. An example of a dental prosthesis includes a first manufactured portion shaped to substantially conform to the three-dimensional surface of a root of a tooth to be replaced and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of the tooth. Furthermore, a CAD/CAM based methods of and systems for manufacturing a customized dental prosthesis are provided. | 2014-03-20 |
20140080094 | DENTURE AND METHOD AND APPARATUS OF MAKING SAME - A method for making a denture comprising a base and a plurality of teeth joined thereto. The method comprises forming a first cavity in a block of a denture base material, the first cavity being formed to match the contour of natural teeth as arranged on maxillae or on a mandible; filling the first cavity with a first fluid synthetic tooth material and solidifying the first fluid synthetic tooth material into a first solid synthetic tooth material; removing a portion of the first solid synthetic tooth material to form the plurality of teeth; and removing a portion of the block of denture base material to form the denture base. The steps of the method may be implemented by a computer. An apparatus for making the denture according to certain embodiments of the method, and a denture comprised of a base and artificial teeth are also disclosed. | 2014-03-20 |
20140080095 | TEMPORARY DENTAL PROSTHESIS FOR USE IN DEVELOPING FINAL DENTAL PROSTHESIS - A method of manufacturing a permanent prosthesis for attachment to a dental implant installed in a mouth of a patient includes scanning a patient specific temporary prosthesis (PSTP) to obtain scan data. The PSTP is attached to the dental implant in the mouth of the patient. Gingival tissue surrounding the PSTP is permitted to heal in the mouth of the patient. In response to aesthetics of the healed gingival tissue surrounding the PSTP in the mouth of the patient not being acceptable, the PSTP is physically modified by (i) removing material from the PSTP, (ii) adding material to the PSTP, or (iii) both. The modified PSTP is scanned and a permanent prosthesis is fabricated as a replica of the modified PSTP using scan data generated from the scan of the modified PSTP. | 2014-03-20 |
20140080096 | Guided Tissue Regeneration Membrane - A guided tissue regeneration membrane has a top surface, a bottom surface and the two surfaces are characterized by the plurality of through conical holes. Each of the plurality of through holes has a base opening on the top surface and a tip opening on the bottom surface. The diameter of the base opening is larger than that of the tip opening The guided tissue regeneration membrane is placed between a hard tissue and a soft tissue of gums with the top surface thereof facing the hard tissue so as to hinder the soft tissue from rapidly growing. The tip openings are available for the soft tissue to supply nutrient to the hard tissue therethrough. The hard tissue can grow from the base openings, through the corresponding through holes and to the soft tissue to repair periodontal tissue. In order to achieve a better affinity for cell growth, the guided tissue membrane surface facing the bony surface is coated with a hydrophilic, bioactive and biocompatible nano scaled oxidation layer. | 2014-03-20 |
20140080097 | REMOVABLE ADHESION MATERIAL - The present invention relates in a first aspect to an adhesion material for use in an individual containing encapsulated phase-change material. In particular, the adhesion material is for cosmetical or medicinal use in the body of an individual. The adhesion material contains encapsulated phase-change material having preferably a phase transition temperature above 40° C., like above 55° C. The adhesion material is particularly useful for adhering elements, like dental restorations, e.g. crowns or bridge, or brackets on elements in the body of an individual, like teeth or implants. That is, the adhesion material is particularly useful for adhering material in dental applications. In another aspect, a method is provided allowing removing a bracket, a crown or bridge, from implants, abutments or teeth. Furthermore, dental implant restoration systems and kits for permanent fixation of implants allowing improved removal thereof are provided. | 2014-03-20 |
20140080098 | SYSTEM AND METHOD OF EVALUATING AND REPORTING THE DRIVING ACUITY AND PERFORMANCE OF A TEST SUBJECT - Systems and methods for dynamically evaluating a test subject during operation/driving of a vehicle via an onboard evaluator are provided for herein. In particular, an onboard evaluator in the vehicle may be activated either automatically or manually by a user to dynamically evaluate the test subject of the vehicle and grade the test subject on his or her driving ability. Once the onboard evaluator has been activated, the location of the vehicle is preferably identified via a global positioning system (GPS) and local driving laws and rules are downloaded based on the identified location of the vehicle. The onboard evaluator then dynamically evaluates a test subject's driving skill set based on a test subject's driving acuity and performance. As the driving skill set is being evaluated, a processor continually calculates a driving grade/score for that particular test subject in relation to the test subject's evaluated driving skill set. | 2014-03-20 |
20140080099 | Performance-Based Simulation System for an Aircraft - A method and apparatus for training in an aircraft. An apparatus comprises an aircraft, a display system associated with the aircraft, a sensor system associated with the aircraft, and a training processor configured to be connected to the aircraft. The training processor is further configured to receive information about an operator, generate constructive data for simulated objects, generate simulation sensor data using the constructive data, and present the simulation sensor data with live sensor data generated by the sensor system on the display system. The training processor is further configured to identify a performance of the operator based on a policy and modify a simulation based on the performance of the operator. | 2014-03-20 |
20140080100 | MOTOR VEHICLE OPERATING DATA COLLECTION ANALYSIS - A method and apparatus for collecting and evaluating powered vehicle operation utilizing on-board diagnostic components and location determining components or systems. The invention creates one or more databases whereby identifiable behavior or evaluative characteristics can be analyzed or categorized. The evaluation can include predicting likely future events. The database can be correlated or evaluated with other databases for a wide variety of uses. | 2014-03-20 |
20140080101 | KIT FOR FORMING PRINTED MESSAGE CARD WITH DISPLAYED ORIGAMI STRUCTURE AND PRINTED MESSAGE CARD FORMED USING SAME - A kit comprises a plurality of printed message cards, a plurality of envelopes, a plurality of sheets of material each from which an instance of an origami structure can be formed, and an article having instructions thereon for creating the instance of the origami structure using one of the sheets of material. Each one of the envelopes has a space for receiving one of the printed message cards. | 2014-03-20 |
20140080102 | SYSTEM AND METHOD FOR A PERSONAL DIET MANAGEMENT - A system and method for enabling a personal diet management service is disclosed. The system enables users to communicate with the system and receive recommendations throughout the day. The system recommends recipes and restaurants serving the recipes based on a plurality of factors comprising of the calorie and nutrient intake of the person for each meal, identified deficiencies based on the recommended daily intake among others. The system also allows user to communicate with restaurants for reserving tables and specifying any further requests. | 2014-03-20 |
20140080103 | Method for teaching a second language using an infant situational approach - Learning a language and speaking a language are two completely different processes which are in no way related. Learning a language is cognitive, linking it to cause and effect, reasoning, and intelligence. Speaking a language is not cognitive and therefore is in no way related to cause and effect, reasoning, and intelligence. | 2014-03-20 |
20140080104 | KANJI STROKE ORDER LEARNING DEVICE, KANJI STROKE ORDER LEARNING SUPPORT METHOD, KANJI STROKE ORDER LEARNING SYSTEM AND RECORDING MEDIUM IN WHICH KANJI STROKE ORDER LEARNING PROGRAM IS RECORDED - Disclosed is a kanji stroke order learning device including a kanji part stroke order storage unit which stores a plurality of stroke order data of kanji parts, a kanji part combination storage unit which stores kanji and kanji parts included in the kanji in association to each other, a kanji specifying unit which specifies any kanji as a specified kanji, a stroke order input unit which inputs stroke order of the specified kanji, a kanji part stroke order determination unit which determines whether the stroke order of the specified kanji input by the stroke order input unit is correct or incorrect for each kanji part included in the specified kanji, and a kanji part stroke order correct/incorrect display control unit which displays a determination result obtained by the kanji part stroke order determination unit for each kanji part included in the specified kanji. | 2014-03-20 |
20140080105 | LEARNING SUPPORT DEVICE, LEARNING SUPPORT METHOD AND STORAGE MEDIUM CONTAINING LEARNING SUPPORT PROGRAM - A learning support device includes a storage unit, first display control unit, detecting unit and second display control unit. The storage unit stores identifying items to identify the type of a word problem which are detectable in the text of the word problem, and stores at least one relation between variables in the identified-type word problem, for each type of the word problem. The first display control unit displays the word problem requiring calculation of an unknown variable from known variables in the text. The detecting unit detects each identifying item in the text of the displayed word problem. The second display control unit reads out a relation about the unknown variable among the relation(s) for the identified-type word problem, and displays the read-out relation as a corresponding relation. | 2014-03-20 |
20140080106 | Method and System for Improving Personal Productivity in Home Environments - Method and system for improving personal productivity in home environments may store state information associated with an environment and one or more users in a knowledge base, detected activity of a user, infer location of the user based on the detected activity, and suggest one or more tasks to be performed based on the inferred user location. | 2014-03-20 |
20140080107 | ROSARY - The invention provides an abbreviated rosary associated with a handheld item. The rosary includes end-indexers, a triad of indexers, a hexad of indexers, and an intermediate indexer interposed the triad and hexad. A religious icon can be further included. The rosary can be attached to, engaged with or integral with the handheld item. | 2014-03-20 |
20140080108 | SYSTEM AND METHOD FOR PRESENTING CUSTOMIZABLE SPORTS WORKOUTS - Disclosed is a web based portal system and method to construct one or more customizable workouts, each including at least one fitness exercises, sports specific skill drills, and a combination of correlated fitness exercise, and a sport specific skill drill, to enhance the performance level of a registered user in a chosen sport, while also increasing a physical body fitness. The system presented on a web based portal system is designed to present textual and visual content in preformatted modules like a fitness exercise library module, sports specific skill drills library module, a user profile management module, a sports training module, an exercise and drill selection module, a nutritional module, and a community module, each including one or more submodules associated thereof. | 2014-03-20 |
20140080109 | IMMERSIVE STORYTELLING ENVIRONMENT - Techniques for providing an immersive storytelling experience using a plurality of storytelling devices. Each of the storytelling devices may be configured to perform one or more actions based on a current context of a story and in response to a stimulus event. The actions include at least one of an auditory and a visual effect. Embodiments also provide a controller device configured to manage a playback of the story, by adjusting the stimulus event and the effect of each of the plurality of storytelling devices, based on the current context of the story, thereby creating an interactive and immersive storytelling experience. | 2014-03-20 |
20140080110 | Automatically Generating Quiz Questions Based on Displayed Media Content - In accordance with some implementations, a method for automatically generating quiz questions is disclosed. The method is performed on a server system having one or more processors and memory storing one or more programs for execution by the one or more processors. The server system receives, from a client system, media information associated with media content displayed on a display associated with the client system. The server system then analyzes the received media information to determine one or more keywords associated with the media information. The server system retrieves one or more facts based on the one or more determined keywords. The server system then automatically generates a quiz question based on the one or more retrieved facts. The server system then transmits the generated quiz question to the client system for display. | 2014-03-20 |
20140080111 | GRAFT OR TISSUE RINSING SOLUTION AND METHOD FOR RINSING SAID GRAFT OR TISSUE BEFORE REVASCULARIZATION - Extracellular organ or tissue rinsing solution, comprising calcium, PEG with a molecular weight of 35 000 at a concentration of at least 4 g/l, and potassium at a concentration of greater than or equal to 1, but less than 10 mmol/l. | 2014-03-20 |
20140080112 | BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION - Methods and devices for stabilizing a biological sample for analysis, comprising the steps of obtaining in a sample collection device a biological sample from a subject, the biological sample including at least one circulating cell-free first nucleic acid from the subject. The methods may include a step of contacting the biological sample while within the sample collection device with a protective agent composition that includes a preservative agent, an optional anticoagulant, and a quenching agent to form a mixture that includes the protective agent composition and the sample. | 2014-03-20 |
20140080113 | BLOOD COMPONENT SAMPLING SYSTEM AND BLOOD PROCESSING SYSTEMS AND METHODS EMPLOYING SAME - A blood component sampling system and method are disclosed. The system is pre-connected and includes a collected blood component container and a reservoir having substantially fixed volume and at least one volumetric indicator indicating a selected volume and a sample container docking station configured to cooperate with a sample collection container. The system and method provide ease of sampling with reduced risk of contamination. | 2014-03-20 |
20140080114 | METHODS, KITS AND COMPOSITIONS FOR INACTIVATION OF VIRAL AGENTS IN WHOLE BLOOD AND RED BLOOD CELL CONCENTRATES - The present invention is directed to methods, kits and compositions for inactivating viral agents in or on articles including blood based products and feature a light sensitive compound selected from the group consisting of hypericin, pseudohypericin and hypocrellin, and a group of light producing compounds comprising luciferase, luciferin and ATP. | 2014-03-20 |
20140080115 | DEVICE AND METHOD FOR MONITORING THE PRESENCE, ONSET AND EVOLUTION OF PARTICULATES IN CHEMICALLY OR PHYSICALLY REACTING SYSTEMS - A device for monitoring particulates includes a means for correlating measurements of pressure across at least one filter, flow rate of a sample through the filter, or a combination thereof to the properties of particulates in a solution. More particularly, the device can be used for monitoring particulates in a reacting system to provide signals to the user or control input to the reacting system to alter the course of the reaction according to a desired path. | 2014-03-20 |
20140080116 | PROCESS TO CONTROL CO CONCENTRATIONS IN FERMENTATIONS - A process for controlling concentration of CO in a bioreactor provides a direct and real time measurement of dissolved CO in a fermentation medium. The process for controlling concentrations of CO in a bioreactor includes contacting an aliquot of fermentation medium with at least one CO binding ligand and at least one microbial inactivator. | 2014-03-20 |
20140080117 | PROCESS TO AVOID INHIBITION OF ACETOGENS BY CO - A process is provided for fermenting CO-containing gaseous substrates. The process is effective for decreasing lag times and maintaining a culture in steady state by controlling CO concentration and minimizing effects of high or low CO concentrations during fermentation. The process includes providing syngas to a first fermentation zone, fermenting the syngas, and determining a CO concentration in a fermentation medium in the first fermentation zone. If the CO concentration in fermentation medium in the first fermentation zone has a value of about 0.12 μM or greater, then at least a portion of the syngas being provided to the first fermentation zone is provided to one or more subsequent fermentation zones in an amount effective for providing a CO concentration in any subsequent fermentation zone of about 0.12 μM or less. | 2014-03-20 |
20140080118 | SAMPLE ASSEMBLY WITH AN ELECTROMAGNETIC FIELD TO ACCELERATE THE BONDING OF TARGET ANTIGENS AND NANOPARTICLES - Described are embodiments of an invention for a sample assembly with an electrical conductor for generating an electromagnetic field to speed up the tagging of target antigens with antiparticles for detection of the antigens by electromagnetic read heads. A sample assembly includes a surface with a first set of antibodies bonded thereon. Target antigens are bonded with the first set of antibodies. A second set of antibodies bonded to nanoparticles are exposed to the sample surface to bond with the target antigens. The electrical conductor generates an electromagnetic field that moves the nanoparticle-labeled antibodies toward the antigens to shorten the time to complete their bonding process. | 2014-03-20 |
20140080119 | MOLECULAR NETS - A molecular net formed as a branched pseudorandom copolymer including two broad classes of subunits: capture agents and linking agents. The subunits self-assemble to form a structure capable of binding to predetermined targets. The binding can then be detected. | 2014-03-20 |
20140080120 | DETECTION OF ANTIBODIES USING AN IMPROVED IMMUNE COMPLEX (IC) ELISA - The present invention relates to the field of diagnostic or analytic methods. In particular, the inventors teach that FcγR such as CD16, CD32 or CD64 may be used for in vitro quantification of antibodies in the form of immune complexes, i.e., complexes formed by antigen and specific antibody. A method for detection and quantification of antibodies in the form of immune complexes is also provided. | 2014-03-20 |
20140080121 | PRIMATE T-LYMPHOTROPIC VIRUSES - Disclosed are compositions and methods related to the isolation and identification of the primate T-lymphotropic viruses, HTLV-3 and HTLV-4. The diversity of HTLVs was investigated among central Africans reporting contact with NHP blood and body fluids through hunting, butchering, and keeping primate pets. Herein it is shown that this population is infected with a variety of HTLVs, including two retroviruses; HTLV-4 is the first member of a novel phylogenetic lineage that is distinct from all known HTLVs and STLVs; HTLV-3 falls within the genetic diversity of STLV-3, a group that has not previously been seen in humans. The present disclosure also relates to vectors and vaccines for use in humans against infection and disease. The disclosure further relates to a variety of bioassays and kits for the detection and diagnosis of infection with and diseases caused by HTLV-3 and HTLV-4 and related viruses. | 2014-03-20 |
20140080122 | Optical Nanosensors Comprising Photoluminescent Nanostructures - Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. Generally, the nanosensors comprise a photoluminescent nanostructure and a polymer that interacts with the photoluminescent nanostructure. In some cases, the interaction between the polymer and the nanostructure can be non-covalent (e.g., via van der Waals interactions). The nanosensors comprising a polymer and a photoluminescent nanostructure may be particularly useful in determining the presence and/or concentration of relatively small molecules, in some embodiments. In addition, in some instances the nanosensors may be capable of determining relatively low concentrations of analytes, in some cases determining as little as a single molecule. In some embodiments, the interaction between the analyte and the nanosensor (e.g., between the analyte and the photoluminescent nanostructure) can be reversible, which may allow, for example, for the reuse of a nanosensor after it has been exposed to an analyte. | 2014-03-20 |
20140080123 | METHODS OF USING A SERUM RESPONSE FACTOR ISOFORM - The present invention encompasses methods of administering SRFΔ3. Administering SRFΔ3 may reduce proliferation of cancer cells, and modulate activity of promoters regulated by serum response factor. | 2014-03-20 |
20140080124 | SYSTEMS AND METHODS FOR DIAGNOSING A PREDISPOSITION TO DEVELOP COLON CANCER - Systems and methods for diagnosing or characterizing a predisposition to colon cancer are provided. Cell nuclei may be evaluated for the presence or quantity of gamma-H2AX foci. Nucleic acids may be evaluated for the presence, type, or quantity of genomic instability or surrogates of dsDNA breaks such as ataxia telangiectasia mutated (ATM), Rad3-related protein (ATR), and Tumor suppressor p53-binding protein 1 (53BP1) in gamma-H2AX foci. Nucleic acids comprising a germline nucleic acid sequence of the ERCC6, WRN, TERT, and FAAP100 genes may be sequenced or probed to determine if the nucleic acid sequence includes one or more alterations that cause genomic instability, dsDNA breaks, or gamma-H2AX foci or otherwise predispose a subject to develop colon cancer. | 2014-03-20 |
20140080125 | Polymorphisms in the FCGR2B Promoter and Uses Thereof - The invention relates to the FCGR2B gene and its promoter. In particular, the invention relates to FCGR2B promoters with specific nucleotides at polymorphic sites. Characterization of the nucleotides at polymorphic sites is useful for characterizing the gene and the protein and is useful for determining predisposition or susceptibility to certain diseases and infections in a subject or a population of subjects. Such characterization of the gene or protein is also useful for determining immunoresponsiveness or responsiveness to therapeutic agents in a subject or population of subjects. Thus, disclosed herein are a variety of related nucleic acids, methods and tools. | 2014-03-20 |
20140080126 | QUANTIFICATION OF NUCLEIC ACIDS AND PROTEINS USING OLIGONUCLEOTIDE MASS TAGS - The invention provides a method for detecting and quantifying the amount of target molecules, such as nucleic acids or proteins in a sample. The target molecules are first recognized and bounded by target-specific probes, generally nucleic acids or proteins that bind specifically to the targets, each of which is labeled with a short single-stranded nucleic acid probe, either DNA or RNA, with distinct molecular weight. This label is called an oligonucleotide mass tag. One or several standard oligonucleotide sequences can be designed with similar sequence but distinct molecular weight to those oligonucleotide mass tags. Then the oligonucleotide mass tags associated with bounded probes and the standard sequences are co-amplified using a pair of common primers. The presence and/or amount of each oligonucleotide mass tag, which corresponds to the amount of corresponding target molecule, is determined by a primer extension reaction and quantification of the primer extension product. | 2014-03-20 |
20140080127 | HETEROARYLCYANINE DYES - The present invention provides heteroaryl functionalized cyanine dyes including a reactive functional moiety, or which are conjugated to a carrier molecule. | 2014-03-20 |
20140080128 | METHOD FOR DETERMINING WHETHER A SUBJECT IS AT RISK OF HAVING OR DEVELOPING A CHRONIC KIDNEY DISEASE - The invention relates to a method for determining whether a subject is at risk of having or developing a chronic kidney disease (CKD) comprising determining the expression level of the periostin gene in a biological sample obtained from said subject. The invention also relates to a method for staging a CKD in a patient comprising determining the expression level of the periostin gene in a biological sample obtained from said patient. The invention further relates to a method for determining the responsiveness of a patient suffering from a CKD to a treatment comprising determining the expression level of the periostin gene in a biological sample obtained from said patient. | 2014-03-20 |
20140080129 | MOBILE APP FOR CHEMICAL DETECTION - The present invention incorporates the camera from a mobile device (phone, iPad, etc.) to capture an image from a chemical test kit and process the image to provide chemical information. A simple user interface enables the automatic evaluation of the image, data entry, gps info, and maintain records from previous analyses. | 2014-03-20 |
20140080130 | COMPOSITIONS AND METHODS FOR DETECTION OF SALMONELLA SPECIES - Described are compositions, methods and kits for detection and/or differential detection of serovars of | 2014-03-20 |
20140080131 | COMPOSITION AND KIT FOR ISOLATING VESICLES AND METHOD OF ISOLATING THE VESICLES USING THE SAME - The invention provides compositions, kits, and methods for analyzing vesicles or vesicle proteins, glycoproteins, lipids or nucleic acids, and may be used for screening ligands that have a binding affinity to vesicles. | 2014-03-20 |
20140080132 | METHOD AND KIT FOR PREDICTING CYTOTOXICITY - A method for predicting ADCC activity in a subject, the method comprising the steps of: (a) preparing a biological sample from the subject, said sample including a leukocyte, (b) bringing a portion of the biological sample and an antibody into contact with each other, (c) detecting expression of at least one marker of ADCC activity selected from the group consisting of tumor necrosis factor super family 15, chemokine CXCL3, and interleukin 6 in the leukocyte in (i) the portion of the sample brought into contact with the antibody and in (ii) another portion of the sample not brought into contact with the antibody, (d) comparing an expression level in portion (i) with the expression level in portion (ii); and (e) predicting presence of the cytotoxic activity when the expression level in portion (i) is higher than the expression level in portion (ii) | 2014-03-20 |
20140080133 | THERMALLY CONTROLLED CHAMBER WITH OPTICAL ACCESS FOR HIGH-PERFORMANCE PCR - Novel methods and systems for polymerase chain reaction (PCR) are disclosed. A PCR device has a bottom heater layer, a central reacting layer, and a top heater layer. The central reacting layer has a PCR reacting chamber connected with fluidics channels. Photoluminescence of a DNA solution in the PCR reactive chamber is carried out through the transparent top layers. | 2014-03-20 |
20140080134 | LIPOCALIN 2 AS A BIOMARKER FOR IL-17 INHIBITOR THERAPY EFFICACY - The present invention provides the use of lipocalin 2 (LCN2) as a biomarker for IL-17 mediated diseases and for monitoring the response of a patient to anti-IL-17 therapy. | 2014-03-20 |
20140080135 | ILCS BASED PATTERN RECOGNITION OF SEPSIS - The present invention refers to a method for recognizing and/or characterizing cellular activity patterns, in particular for diagnostic purposes and/or for tracking the therapy of diseases. Blood cells are stimulated in a culture medium at least with toll-like receptor ligands (TLR ligands) and the stimulated blood cells and/or the culture medium are examined. | 2014-03-20 |
20140080136 | COMPOSITIONS, KITS, AND METHODS FOR DETECTING AND ANALYZING VESICLES - Provided are compositions, kits, and methods for detecting a vesicle comprising a membrane permeable marker that is converted into a detectable marker inside the vesicle. | 2014-03-20 |
20140080137 | MODIFIABLE CHEMICAL INDUCERS OF PROXIMITY AND METHODS OF USING THE SAME - Methods of reversibly inducing proximity of first and second target molecules in a sample are provided. Aspects of the methods include contacting the sample with a modifiable chemical inducer of proximity (MCIP) that reversibly induces proximity of the first and second target molecules, upon application of a stimulus that modifies the MCIP. Aspects of the invention further include methods for regulating a biological process in a cell. Aspects of the invention further include compositions, e.g., compounds and kits, etc., that find use in methods of the invention. | 2014-03-20 |
20140080138 | Biomarkers for Head-and-Neck Cancers and Precancers - The invention provides markers and methods for detecting head-and-neck precancers, (including OPLs), cancers and related disease conditions in a subject. The invention also provides localization and imaging methods for head-and-neck precancers (including OPLs) and cancers, along with kits for carrying out methods of the invention. The invention further provides therapeutic applications for head-and-neck precancers (including OPLs) and cancers which employ head-and-neck precancer and cancer markers, and binding agents for the markers. Methods of identifying a subject having oral dysplasia that is at high risk of malignant transformation are provided. | 2014-03-20 |
20140080139 | HIGH-SENSITIVITY NANOSCALE WIRE SENSORS - One aspect of the invention provides a nanoscale wire that has improved sensitivity, for example, as the carrier concentration in the wire is controlled by an external gate voltage. In one set of embodiments, the nanoscale wire has a Debye screening length that is greater than the average cross-sectional dimension of the nanoscale wire when the nanoscale wire is exposed to a solution suspected of containing an analyte. In certain instances, the Debye screening length associated with the carriers inside nanoscale wire may be adjusted by adjusting the voltage, for example, a gate voltage applied to an FET structure. In some cases, the nanoscale wire can be operated under conditions where the carriers in the nanoscale wire are depleted and the nanoscale wire has a conductance that is not linearly proportional to the voltage applied to the nanoscale wire sensor device, for example, via a gate electrode. | 2014-03-20 |
20140080140 | SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS - Methods for screening for neurological disorders are disclosed. Specifically, methods are disclosed for screening for neurological disorders in a subject by analyzing a tissue sample obtained from the subject for the presence of elevated levels of neurotoxic amino acids or neurotoxic derivatives thereof associated with neurological disorders. In particular, methods are disclosed for diagnosing a neurological disorder in a subject, or predicting the likelihood of developing a neurological disorder in a subject, by determining the levels of β-N-methylamino-L-alanine (BMAA) in a tissue sample obtained from the subject. Methods for screening for environmental factors associated with neurological disorders are disclosed. Methods for inhibiting, treating or preventing neurological disorders are disclosed. | 2014-03-20 |
20140080141 | CLEAR MARGIN DETERMINATION DURING CANCER SURGERY - One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue. | 2014-03-20 |
20140080142 | Compositions and Methods of Using Differentiated Cells Sensitized to Botulinum Neurotoxin - Differentiated cholinergic cells having motor neuron-like morphology and increased sensitivity to botulinum neurotoxin are provided herein. Methods of using such differentiated cells for detecting neurotoxin are also provided. | 2014-03-20 |
20140080143 | PSA ASSAY AND REAGENT THEREFOR - Provided is a method for the simple and highly accurate assay of PSA by a one-step reaction that does not use carriers having different average grain sizes. Also provided is a reagent therefor. The PSA assay method comprises sensitizing insoluble carriers having the same average grain size within a range of greater than 0.20 μm but 0.40 μm or less using two types of anti-PSA monoclonal antibodies having different epitopes that are anti-PSA monoclonal antibodies that will react with both free PSA and PSA-ACT, which is a complex of free PSA and α1-antichymotrypsin, and bringing the carriers into contact with a sample in the presence of an aggregation promoter. | 2014-03-20 |