09th week of 2015 patent applcation highlights part 41 |
Patent application number | Title | Published |
20150056656 | METHOD FOR REDUCTION OF 1->2 READING FRAME SHIFTS - Herein is reported a method for the recombinant production of a polypeptide, which comprises the dipeptide AR, characterized in that the method comprises the recovering of the polypeptide from the cells or the cultivation medium of a cultivation of a cell comprising a nucleic acid encoding the polypeptide and thereby producing the polypeptide, whereby the dipeptide AR comprised in the polypeptide is encoded by the oligonucleotide gca cgt, or the oligonucleotide gcg cgt, or the oligonucleotide gcc cgt. | 2015-02-26 |
20150056657 | METHOD OF PRODUCING RECOMBINANT HIGH MOLECULAR WEIGHT vWF IN CELL CULTURE - Among other aspects, the present invention relates to cell culture conditions for producing high molecular weight vWF, in particular, highly multimericWF with a high specific activity and ADAMTS13 with a high specific activity. The cell culture conditions of the present invention can include, for example, a cell culture medium with an increased copper concentration and/or cell culture supernatant with a low ammonium (NH | 2015-02-26 |
20150056658 | CELLS, NUCLEIC ACIDS, ENZYMES AND USE THEREOF, AND METHODS FOR THE PRODUCTION OF SOPHOROLIPIDS - The invention relates to cells, nucleic acids, and enzymes, the use thereof for producing sophorolipids, and methods for producing sophorolipids. | 2015-02-26 |
20150056659 | CELLS, NUCLEIC ACIDS, ENZYMES AND USE THEREOF, AND METHODS FOR THE PRODUCTION OF SOPHOROLIPIDS - The invention relates to cells, nucleic acids, and enzymes, the use thereof for producing sophorolipids, and methods for producing sophorolipids. | 2015-02-26 |
20150056660 | CELLS, NUCLEIC ACIDS, ENZYMES AND USE THEREOF, AND METHODS FOR THE PRODUCTION OF SOPHOROLIPIDS - The invention relates to cells, nucleic acids, and enzymes, the use thereof for producing sophorolipids, and methods for producing sophorolipids. | 2015-02-26 |
20150056661 | CELLS, NUCLEIC ACIDS, ENZYMES AND USE THEREOF, AND METHODS FOR THE PRODUCTION OF SOPHOROLIPIDS - The invention relates to cells, nucleic acids, and enzymes, the use thereof for producing sophorolipids, and methods for producing sophorolipids. | 2015-02-26 |
20150056662 | System and Method for Nucleic Acid Amplification - An embodiment of a method for generating a population of amplified concatamer products is described that comprises amplifying a template nucleic acid molecule using a first nucleic acid primer immobilized on a bead substrate and a second nucleic acid primer in solution to generate a population of substantially identical copies of the template nucleic acid molecule immobilized on the bead substrate; and amplifying the population of substantially identical copies of the template nucleic acid molecule using a concatamer primer that comprises a first region complementary to an end region of the population of substantially identical copies of the template nucleic acid molecule and a second region to generate a population of immobilized concatamer products of the substantially identical copies of the template nucleic acid molecule. | 2015-02-26 |
20150056663 | SYSTEM AND METHOD FOR AUTOMATED NUCLEIC ACID AMPLIFICATION - An embodiment of a device for automatically executing a process of generating an emulsion containing nucleic acids, amplifying the nucleic acids in the emulsion, breaking the emulsion, and separating and purifying said amplified nucleic acids, is described that comprises an emulsion generation unit for sealing beads to which nucleic acids are bound in a water-in-oil type emulsion; a nucleic acid amplification unit provided with a reaction vessel for amplifying said nucleic acids and a heating and cooling part for heating and cooling the reaction vessel; an emulsion breaking unit for breaking the emulsion after nucleic acid amplification; and a nucleic acid purification unit for recovering said amplified nucleic acids from said emulsion breaking unit. | 2015-02-26 |
20150056664 | Variants of Glycoside Hydrolases - The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences. | 2015-02-26 |
20150056665 | METHOD OF PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION AND CONTINUOUS FERMENTATION APPARATUS - A method of producing a chemical includes culturing cells in a culture solution in a fermentor to ferment a feedstock to produce a chemical; supplying the culture solution containing the chemical produced in the culturing to a plurality of separation membrane units arranged in parallel; filtering the culture solution supplied in the supplying to separate a permeate containing the chemical; refluxing a retentate that is not filtered in the filtering to the fermentor; and supplying a gas containing oxygen to the plurality of separation membrane units while a supply amount is changed to at least two different values to perform scrubbing, wherein the supply amount and supply time of the gas containing oxygen supplied in the culturing and the supplying the gas are set so that a kLa value is within a predetermined range from an optimal kLa value for the cells cultured in the culturing. | 2015-02-26 |
20150056666 | VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE - The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism. | 2015-02-26 |
20150056667 | MUTANTS OF HYDANTOINASE - The present invention relates to a hydantoinase having an amino acid sequence selected from (i) or (ii), with (i) amino acid sequence selected from SEQ ID NO: 6-20 and SEQ ID NO: 73-119 (ii) amino acid sequence wherein in the amino acid sequence of SEQ ID NO: 6-20 and SEQ ID NO: 73-119, 1 to 75 amino acid residues have been substituted, deleted, inserted and/or added, and wherein further the catalytic activity of the hydantoinase is higher by a factor of at least 1.2 than the catalytic activity of the hydantoinase having amino acid sequence SEQ ID NO: 1, The present invention further relates to a process for preparing amino acids, wherein said hydantoinase is used. | 2015-02-26 |
20150056668 | SYNTHESIS OF PRAZOLE COMPOUNDS - The present disclosure relates to non-naturally occurring monooxygenase polypeptides useful for preparing prazole compounds, polynucleotides encoding the polypeptides, and methods of using the polypeptides. | 2015-02-26 |
20150056669 | ACETYL-COA CARBOXYLASES - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 2015-02-26 |
20150056670 | MICROORGANISM PRODUCING 4-HYDROXYBUTYRATE AND A METHOD FOR PRODUCING 4-HYDROXYBUTYRATE IN ANAEROBIC CONDITION USING THE SAME - A genetically modified microorganism comprising a polynucleotide encoding α-ketoglutarate synthase or a mutant thereof, and a polynucleotide encoding pyruvate carboxylase or a mutant thereof; wherein the genetically modified microorganism has decreased malate quinone oxidoreductase activity and/or decreased phosphoenolpyruvate carboxykinase activity compared to an unmodified microorganism of the same type, and wherein the genetically modified microorganism produces 4-hydroxybutyrate. | 2015-02-26 |
20150056671 | METHOD FOR PRODUCING FATTY ACID ESTER - Provided is a method of producing a fatty acid ester in a high yield through a simple operation using | 2015-02-26 |
20150056672 | SYSTEMS AND METHODS FOR PRODUCING EICOSAPENTAENOIC ACID AND DOCOSAHEXAENOIC ACID FROM ALGAE - Provided herein are systems and methods for producing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and/or derivatives and/or mixtures thereof by growing algae that produce the oils containing EPA and/or DHA and/or derivatives and/or mixtures thereof, harvesting the algae with fish in one or more enclosed systems, and then processing fish to separate and purify the EPA and/or DHA. The multi-trophic systems provided herein comprise at least one enclosure that contains the algae and the fishes, and means for controllably feeding the algae to the fishes. Also provided herein are the lipid compositions extracted from the fishes. | 2015-02-26 |
20150056673 | RECOMBINANT MICROORGANISM - The invention concerns a microorganism which is genetically modified so as to i) synthesize a hydrocarbon monomer by fermentation of a carbon source, and ii) depolymerize a polymer constituted at least by hydrocarbon monomer which it is capable of synthesizing. The invention also concerns a method for producing a hydrocarbon monomer using a genetically modified microorganism of this type, as well as the coculture of this microorganism with another microorganism which is capable of synthesizing a polymer of interest. | 2015-02-26 |
20150056674 | FERMENTATION PROCESS FOR CONVERGING CELLULOSIC SUGARS TO ETHANOL - Methods using yeast, enzymes and bacteria to increase ethanol production rates from cellulosic sugars via multiple coupled fermentation processes. | 2015-02-26 |
20150056675 | HYDROCARBON SYNTHASE GENE AND USE THEREOF - A hydrocarbon synthase gene encoding protein having excellent capacity to synthesize a hydrocarbon such as alkane and novel functions is provided. The gene encodes a protein comprising an amino acid sequence comprising a motif sequence shown in SEQ ID NO: 1 and having activity of synthesizing a hydrocarbon with a carbon number one less than that of an aldehyde compound from the aldehyde compound. | 2015-02-26 |
20150056676 | Two-Stage Anaerobic Digestion Systems Wherein One of the Stages Comprises a Two-Phase System - Low cost, efficient two-stage anaerobic digestion systems for the production of biogas (e.g. methane) are provided. During the first stage, biogas is produced in a first reactor by anaerobic microbes cultured in two phases: a high solids phase and a low solids phase. During the second stage, biogas is produced in a second reactor by a methanogen-rich anaerobic culture cultured in low solids medium. Removal of effluent comprising pH lowering reaction products assists in maintaining a suitable pH in the high solids phase. The transfer of effluent from the second reactor to the first reactor assists in maintaining a suitable pH in the high solids phase, in mixing of the high solids phase, and in reseeding the high solids phase with methanogens. Methane is produced in and recovered from both reactors. | 2015-02-26 |
20150056677 | MICROBES AND METHODS FOR REDUCING COMPOUNDS - Provided herein are biologically pure cultures of microbes having the characteristic of reducing Sb(V) to Sb(III). In one embodiment, the microbes produce Sb | 2015-02-26 |
20150056678 | DISEASE THERAPY USING DYING OR DEAD CELLS - A method of treating a disease characterized by a pathological immune response in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically effective amount of a cell preparation which comprises dying or dead leukocytes, the dying or dead leukocytes being capable of suppressing the pathological immune response, thereby treating the disease in the subject. | 2015-02-26 |
20150056679 | METHOD OF ENZYME INACTIVATION - The present invention relates to a method for the inactivation of enzymes with a composition comprising a sulfonated peroxycarboxylic acid according to formula (I) wherein: R | 2015-02-26 |
20150056680 | Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses - The present invention concerns methods and compositions for stably tethered structures of defined compositions, which may have multiple functionalities and/or binding specificities. Particular embodiments concern homodimers comprising monomers that contain a dimerization and docking domain attached to a precursor. The precursors may be virtually any molecule or structure, such as antibodies, antibody fragments, antibody analogs or mimetics, aptamers, binding peptides, fragments of binding proteins, known ligands for proteins or other molecules, enzymes, detectable labels or tags, therapeutic agents, toxins, pharmaceuticals, cytokines, interleukins, interferons, radioisotopes, proteins, peptides, peptide mimetics, polynucleotides, RNAi, oligosaccharides, natural or synthetic polymeric substances, nanoparticles, quantum dots, organic or inorganic compounds, etc. Other embodiments concern tetramers comprising a first and second homodimer, which may be identical or different. The disclosed methods and compositions provide a facile and general way to obtain homodimers, homotetramers and heterotetramers of virtually any functionality and/or binding specificity. | 2015-02-26 |
20150056681 | Method for Improving Solubility of Alkaline Protease - Providing an alkaline protease exhibiting an improved solubility in a liquid detergent. A mutant alkaline protease consisting of the amino acid sequence represented by SEQ ID No: 2 or an amino acid sequence having 80% or more sequence identity therewith, in which at least one amino acid residue selected from the group consisting of the amino acid residues at predetermined positions of the amino acid sequence represented by SEQ ID No: 2 or corresponding positions thereto are substituted. | 2015-02-26 |
20150056682 | Compositions and Methods Comprising Variant Microbial Proteases - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications. | 2015-02-26 |
20150056683 | LACTOBACILLUS CULTURE AND METHOD FOR PRODUCING SAME - An object of the present invention is to provide a technique for improving a taste derived from | 2015-02-26 |
20150056684 | METHODS, SYSTEMS, AND COMPOSITIONS FOR INCREASED MICROORGANISM TOLERANCE TO AND PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP) - The present invention relates to methods, systems and compositions, including genetically modified microorganisms, adapted to exhibit increased tolerance to 3-hydroxypropionic acid (3-HP), particularly through alterations to interrelated metabolic pathways identified herein as the 3-HP toleragenic pathway complex (“3HPTGC”). In various embodiments these organisms are genetically modified so that an increased 3-HP tolerance is achieved. Also, genetic modifications may be made to provide at least one genetic modification to any of one or more 3-HP biosynthesis pathways in microorganisms comprising one or more genetic modifications of the 3HPTGC. | 2015-02-26 |
20150056685 | Method and Device for Feeding Gases or Gas Mixtures into a Liquid, Suspension or Emulsion in a Reactor in a Specific Manner - The invention relates to a method and to a device for feeding gases or gas mixtures into a liquid, suspension, or emulsion in a reactor in a specific manner. According to the invention, gases or gas mixtures are fed into a liquid, suspension, or emulsion in a reactor in a specific manner, wherein the gas or gas mixture is fed in a specific amount and/or at defined points in time in one pulse as a gas bubble into a flowing liquid in a tilted reactor system, whereby a pulsation effect is obtained, wherein a driving force is produced by means of an adiabatic relaxation of the fed-in gas or gas mixture, by means of which driving force wall adhesions on the reactor are prevented. | 2015-02-26 |
20150056686 | GAS-BORNE PATHOGEN SENSOR APPARATUSES AND METHODS THEREOF - A gas-borne pathogen sensor apparatus includes a chamber in a housing having a gas inlet, a gas outlet, and a collection area with a fluid exit port, a liquid misting device, and a sensor element. The liquid misting device is coupled to the chamber and is positioned to spray fluid into the chamber in the housing. The sensor element is positioned in the chamber in the housing and has one or more probes designed to mate with any of one or more targets in a gas supplied to the chamber in the housing through the gas inlet. | 2015-02-26 |
20150056687 | LATERAL FLOW DEVICES AND METHODS OF MANUFACTURE AND USE - A lateral flow assay test device providing a structure for the lateral flow assay reactions provides for a continuous flow path of bibulous material provided in separate but contiguous regions of the device in which the bibulous layers are in fluid contact with each other thereby providing flow control of the timing and speed of the assay reaction. Increased flow control results in increasing reliability of use, increasing sophistication of reactions and increases the range of molecules or diagnosis that can be identified. Such flow control can extend processing times and allow users or test givers to manually delay test processing providing enhanced test results. | 2015-02-26 |
20150056688 | Dual Path Immunoassay Device - Systems include test cells with sorbent material in a T-shape and defining a first flow path for a solution and a second flow path for a sample, and a test line or test site with immobilized antigens or antibodies or other ligand binding molecules located at the junction of the T. A housing houses the sorbent material and defines a first hole adjacent an end of the first flow path for receiving the solution and a second hole adjacent an end of the second flow path for receiving the sample. | 2015-02-26 |
20150056689 | SYSTEM LAYOUT FOR AN AUTOMATED SYSTEM FOR SAMPLE PREPARATION AND ANALYSIS - A sample preparation and analysis system. The system includes a housing with a sample preparation station and a sample analysis station positioned within the housing. The sample analysis station is spaced away from the sample preparation station. A transport assembly is configured to move at least one sample within the housing and between the sample preparation station and the sample analysis station. | 2015-02-26 |
20150056690 | SPECTRAL IMAGING OF BIOLOGICAL SAMPLES - The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components. | 2015-02-26 |
20150056691 | Apparatus and methods for cell isolation - A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form. | 2015-02-26 |
20150056692 | Spouted Bed Bio-Reactor System - The invention describes a novel spouted bed bioreactor system (SBBS) for the removal of Benzene, Toluene, Ethyl-benzene, o-,m-,p-Xylene (BTEX) from a contaminated air stream. Organic-degrading bacteria, | 2015-02-26 |
20150056693 | STERILE INDIVIDUAL SET FOR PRODUCING BIOPHARMACEUTICAL PRODUCTS - A sterile individual set for use in a process of manufacturing a biopharmaceutical product. To make it quicker and easier to grasp and use fluidic type functional members, the sterile individual set includes a sterile flexible bag having a peripheral wall defining a sterile internal space and a fluidic type functional member arranged at least partially inside the sterile internal space. The functional member includes one or more communication duct(s) arranged in the sterile internal space. The sterile individual set also includes structural association elements capable of holding together several portions of the communication duct or ducts that are to be bundled together into a bundle. The structural association elements have an external surface with lower static and dynamic friction coefficients so as to make the functional member easier to handle by slippage of the bundle of communication ducts with respect to the peripheral wall of the flexible bag. | 2015-02-26 |
20150056694 | BAG LOCKING MECHANISM - The invention relates to a bag locking mechanism comprising, a fixed locking means ( | 2015-02-26 |
20150056695 | APPARATUS FOR SPREADING A FLUID ACROSS A SUBSTRATE AND METHOD OF USING THE SAME - This disclosure is directed to an apparatus and method for spreading a fluid across a substrate. A spreader for spreading a fluid across a substrate includes a wiper and a frame. The wiper and the frame may mate to permit translation of the wiper across, and with respect to, the frame. The wiper spreads the fluid across the substrate and the frame supports the wiper and the substrate. The frame may also include a ramp to cause a portion of the wiper to lift away from the substrate. | 2015-02-26 |
20150056696 | RECOMBINANT LENTIVIRAL VECTOR PREPARATION - Herein is provided a recombinant lentiviral vector preparation, in which the preparation comprises: a) an effective dose of the recombinant lentiviral vector; b) a histidine hydrochloride buffer for keeping a pH value of the preparation in the range of 6.0-8.0; and c) a carbohydrate. | 2015-02-26 |
20150056697 | PLURIPOTENT STEM CELLS AND METHOD OF STIMULATING AND EXTRACTING NON-EMBRYONIC PLURIPOTENT STEM CELLS FROM MAMMAL BLOOD AND USING RECONSTITUTED PLURIPOTENT STEM CELLS TO TREAT DISEASES INCLUDING CHRONIC OBSTRUCTIVE PULMONARY DISEASE - Stimulating tissue resident pluripotent stem cells in a manner that the respective subject (e.g., human) acts as its own sterile bioreactor for in vivo stem cell proliferation thus eliminating the need to isolate, cultivate, maintain, proliferate and release stem cells ex vivo. The stimulation mobilizes excess pluripotent stem cells into the peripheral vasculature where the pluripotent stem cells can either migrate to damaged tissues and/or be harvested by simple venipuncture, thus eliminating potential morbidity and mortality elicited from harvesting tissue from solid tissue sites. The pluripotent stem cells are separated from the blood by gravity sedimentation, after which the pluripotent stem cells can easily be aspirated from the white blood cells and red blood cells. Billions of pluripotent stem cells can be generated in this fashion for infusion/injection into the body, via the vasculature, and into the organ(s) in need of tissue repair and regeneration. | 2015-02-26 |
20150056698 | PRIMATE EMBRYONIC STEM CELLS - A purified preparation of primate embryonic stem cells is disclosed. This preparation is characterized by the following cell surface markers: SSEA-1 (−); SSEA-4 (+); TRA-1-60 (+); TRA-1-81 (+); and alkaline phosphatase (+). In a particularly advantageous embodiment, the cells of the preparation are human embryonic stem cells, have normal karyotypes, and continue to proliferate in an undifferentiated state after continuous culture for eleven months. The embryonic stem cell lines also retain the ability, throughout the culture, to form trophoblast and to differentiate into all tissues derived from all three embryonic germ layers (endoderm, mesoderm and ectoderm). A method for isolating a primate embryonic stem cell line is also disclosed. | 2015-02-26 |
20150056699 | SMALL MOLECULE INDUCERS OF GDNF AS POTENTIAL NEW THERAPEUTICS FOR NEUROPSYCHIATRIC DISORDERS - This invention provides a compound having the structure | 2015-02-26 |
20150056700 | BONE MORPHOGENIC PROTEIN BINDING PEPTIDE - A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the overall osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis. | 2015-02-26 |
20150056701 | CELL SUSPENSION MEDIUM AND CELL SUSPENSION MEDIUM ADDITIVE FOR THE THREE DIMENSIONAL GROWTH OF CELLS - The present invention relates to a cell culture medium additive comprising a xanthan polysaccharide and a mannan polysaccharide, such as a glucomannan or a galactomannan, that supports the growth of cells in suspension, and to a cell culture medium containing the additive. More particularly, but not exclusively, the present invention relates to a cell culture medium additive that supports the formation of multicellular bodies such as spheroids, and prevents sedimentation of cells without adversely affecting the physical properties of the cell culture medium. | 2015-02-26 |
20150056702 | METHOD AND KIT FOR CULTURING STEM CELLS - A method is provided, including adding a phthalide to a stem cell medium to provide a phthalide-containing medium, and then culturing a stem cell using the phthalide-containing medium. The use of a phthalide in a medium for culturing stem cells optionally maintains the pluripotency of stem cells. The phthalide also enhances the generation efficiency of induced pluripotent stem cells to decrease the culture cost. | 2015-02-26 |
20150056703 | FIBER SCAFFOLDS FOR ENHANCING CELL PROLIFERATION IN CELL CULTURE - A substrate for culturing cells that includes at least one fiber scaffold adapted to be contained within a disposable or non-disposable bioreactor, wherein the fiber scaffold further includes polymer fibers that have been created by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both. | 2015-02-26 |
20150056704 | METHODS AND PRODUCTS FOR BIASING CELLULAR DEVELOPMENT - Methods are described that bias cells, such as potent and multipotent stem cells, by transfection with a nucleic acid sequence, to differentiate to a desired end-stage cell or a cell having characteristics of a desired end-stage cell. In particular embodiments, human neural stem cells are transfected with vectors comprising genes in the homeobox family of transcription factor developmental control genes, and this results in a greater percentage of resultant transformed cells, or their progeny, differentiating into a desired end-stage cell or a cell having characteristics of a desired end-stage cell. | 2015-02-26 |
20150056705 | METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION - Methods and compositions for genetic alteration of cells are provided. | 2015-02-26 |
20150056706 | VECTOR - The present invention now provides a conditional vector comprising DNA encoding for: (i) an inducible expression cassette comprising an inducible promoter operably linked to a plasmid replication region; and (ii) a selectable marker. | 2015-02-26 |
20150056707 | ENGINEERING SALT TOLERANCE IN PHOTOSYNTHETIC MICROORGANISMS - Provided herein are compositions and methods for engineering salt tolerance and producing products by photosynthetic organisms. The photosynthetic organisms can be genetically modified to be salt tolerant as compared to an unmodified organism and to produce useful products. The methods and compositions of the disclosure are useful in many therapeutic and industrial applications. | 2015-02-26 |
20150056708 | METHODS FOR DETECTING ESTRONE BY MASS SPECTROMETRY - Provided are methods for determining the amount of estrone in a sample using mass spectrometry. The methods generally involve ionizing estrone in a sample and detecting and quantifying the amount of the ion to determine the amount of estrone in the sample. | 2015-02-26 |
20150056709 | METHOD FOR CHARACTERIZATION OF THE RATE OF MOVEMENT OF AN OXIDATION FRONT IN CEMENTITIOUS MATERIALS - Disclosed are methods for determining the redox condition of cementitious materials. The methods are leaching methods that utilize a redox active transition metal indicator that is present in the cementitious material and exhibits variable solubility depending upon the oxidation state of the indicator. When the leaching process is carried out under anaerobic conditions, the presence or absence of the indicator in the leachate can be utilized to determine the redox condition of and location of the oxidation front in the material that has been subjected to the leaching process. | 2015-02-26 |
20150056710 | CHARACTERIZATION OF POLYMER AND COLLOID SOLUTIONS - Simultaneous Multiple Sample Light Scattering systems and methods can be used to for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces. among others, that create a polymer stress response used to characterize the polymer solution and stability. | 2015-02-26 |
20150056711 | Explosive Detection Polymer Comprising Functionalized Polyamine Polymers and Methods of Using the Same - Explosives detection polymers are provided that include a polyamine polymer, such as polyethylenimine, functionalized with a small molecule fluorophore. Methods for detecting an explosive material using polyamine polymers functionalized with a small molecule fluorophore are also provided. Sensors for explosive detection are provided that include a polyamine polymer functionalized with a small molecule fluorophore and a complementary analytical device. | 2015-02-26 |
20150056712 | Methods for Analyzing Cysteamine Compositions - Methods of analyzing purity of compositions comprising cysteamine and detecting impurities in cysteamine compositions are described. | 2015-02-26 |
20150056713 | Measurement of Biologically Labile Hydrogen Sulfide Pools - A method to measure all relevant biologic hydrogen sulfide pools, namely free hydrogen sulfide, acid-labile sulfide, and bound sulfane sulfur, has been developed. This new method involves selective liberation, trapping and derivatization of labile hydrogen sulfide. The total labile sulfide, including the contribution of the bound sulfane sulfur pool, the acid-labile pool, and free H2S, was measured by incubating the sample with a reducing agent, TCEP (Tris(2-carboxyethyl)phosphine hydrochloride), to reduce disulfide bonds in an acid solution. This method was used to measure the three sulfide pools in blood samples from mice and from humans. This method can be used for research, environmental, and clinical diagnostic purposes in determining hydrogen sulfide bioavailability in biological or other samples. | 2015-02-26 |
20150056714 | METHOD FOR CHARACTERIZATION OF THE REDOX CONDITION OF CEMENTITIOUS MATERIALS - Disclosed are methods for determining the redox condition of cementitious materials. The methods are leaching methods that utilize an in situ redox indicator that is present in the cementitious materials as formed. The in situ redox indicator leaches from cementitious material and, when the leaching process is carried out under anaerobic conditions can be utilized to determine the redox condition of the material. The in situ redox indicator can exhibit distinct characteristics in the leachate depending upon the redox condition of the indicator. | 2015-02-26 |
20150056715 | METHOD AND SYSTEM FOR ACOUSTICALLY TREATING MATERIAL - Methods and systems for acoustically treating material using an acoustic energy system having a movable outer surface that contacts a sample holder. The outer surface may be cylindrical and rotate about a central axis, e.g., so that a sample holder may be driven to move by the outer surface. Acoustic energy may be emitted from within the outer surface to a treatment area outside of, and near, the outer surface. Thus, a sample holder in contact with the outer surface may have a sample exposed to acoustic energy while rotation of the outer surface may move the sample holder relative to treatment area. One or more additional rollers or other components may bias the sample holder into contact with the outer surface, to e.g., so the sample holder is squeezed between the outer surface and a roller or other biasing component. | 2015-02-26 |
20150056716 | Sample collection device - A sample collection device having a sample tube, funnel, and cap having a capsule and a piercing insert, the capsule having a stabilization solution. After depositing the sample into the tube via the funnel, the cap is screwed onto the tube, piercing the capsule and releasing the stabilization fluid into the tube. The device can be used at home without clinicial supervision for collecting a saliva sample and transporting the sample to an analysis location for DNA analysis. | 2015-02-26 |
20150056717 | Microfluidic Metering of Fluids - This document provides methods and devices for metering fluids. In some cases, the methods and devices include intersecting channels that include capillary-stop geometries at each intersection point that guides the fluids on a desired path, which is controlled by the opening and closing of valves. For example, a metering channel can intersect a loading channel and intersect an outflow channel and a metering portion can be defined by the geometry of the metering channel between the intersection points. | 2015-02-26 |
20150056718 | DUAL SYRINGE - A dual syringe is provided. The dual syringe includes a first barrel and a second barrel. The first barrel may slidably engage within the second barrel. A first chamber and a second chamber may be formed in the first barrel. A first plunger may be slidably engaged within the first chamber and a second plunger may be slidably engaged within the second chamber. A first valve may be attached in between the first chamber and a mixing chamber of the second barrel | 2015-02-26 |
20150056719 | Universal Rapid Diagnostic Test Reader with Trans-Visual Sensitivity - A universal rapid diagnostics test reader is disclosed and described herein that includes a set of control electronics, a digital camera component, an illumination component, a housing component, and a rapid diagnostics test tray, wherein the tray can hold at least one rapid diagnostics test having a shape and a size in a fixed position relative to the digital camera component and the illumination component, and wherein the reader can accommodate more than one different rapid diagnostics test. Methods are also disclosed that include: providing at least one first rapid diagnostics test having a first physical size, first feature and first format; providing at least one second rapid diagnostics test having a second physical size, second feature and second format; inserting the first rapid diagnostics test in a universal rapid diagnostics test reader; analyzing the first rapid diagnostics test using the universal rapid diagnostics test reader; removing the first rapid diagnostics test from the reader; inserting the second rapid diagnostics test in a universal rapid diagnostics test reader without any mechanical adjustments of the reader or without the use of any additional parts or additional inserts; and analyzing the second rapid diagnostics test using the universal rapid diagnostics test reader. | 2015-02-26 |
20150056720 | DEVICE AND METHOD FOR ANALYZING TARGET - The present invention provides a novel sensor for detecting a target. The nucleic acid sensor of the present invention includes a nucleic acid element that includes a catalyst nucleic acid molecule (D) that exerts a catalytic function and a binding nucleic acid molecule (A) that binds to a target. The nucleic acid element is a double-stranded nucleic acid element including a first strand and a second strand. The first strand (ss1) includes the binding nucleic acid molecule (A), a loop-forming sequence (L1), and the catalyst nucleic acid molecule (D) linked in this order. The second strand (ss2) includes a stem-forming sequence (S | 2015-02-26 |
20150056721 | SNTF IS A BLOOD BIOMARKER FOR THE DIAGNOSIS AND PROGNOSIS OF SPORTS-RELATED CONCUSSION - The invention relates to methods for providing prognosis, diagnosis, monitoring and treatment of a mild traumatic brain injury (mTBI) in a subject, including a sports-related concussion. The invention further relates to assessing the severity of brain damage resulting from mTBI in a subject, including in a subject who has not undergone a CT scan following the injury. For example, the methods of the invention can be used to determine the suitability for someone who has suffered a sports-related injury to return to play that sport. This invention also relates to methods of predicting risk for developing brain damage and long-term dysfunction in a subject having suffered mTBI. | 2015-02-26 |
20150056722 | MTJ STRUCTURE AND INTEGRATION SCHEME - A memory device may comprise a magnetic tunnel junction (MTJ) stack, a bottom electrode (BE) layer, and a contact layer. The MTJ stack may include a free layer, a barrier, and a pinned layer. The BE layer may be coupled to the MTJ stack, and encapsulated in a planarized layer. The BE layer may also have a substantial common axis with the MTJ stack. The contact layer may be embedded in the BE layer, and form an interface between the BE layer and the MTJ stack. | 2015-02-26 |
20150056723 | Processing Substrates Using Site-Isolated Processing - Substrate processing systems and methods are described for processing substrates having two or more regions. The processing includes one or more of molecular self-assembly and combinatorial processing. At least one of materials, processes, processing conditions, material application sequences, and process sequences is different for the processing in at least one region of the substrate relative to at least one other region of the substrate. Processing systems are described that include numerous processing modules. The modules include a site-isolated reactor (SIR) configured for one or more of molecular self-assembly and combinatorial processing of a substrate. | 2015-02-26 |
20150056724 | INTEGRATED CIRCUIT LAYOUT AND METHOD WITH DOUBLE PATTERNING - The present disclosure provides one embodiment of a method for an integrated circuit (IC). The method includes forming a mandrel pattern on a substrate by a first lithography process; forming a first spacer pattern on sidewalls of the mandrel pattern; removing the mandrel pattern; forming a second spacer pattern on sidewalls of the first spacer pattern; removing the first spacer pattern; and etching the substrate using the second spacer pattern as an etch mask. | 2015-02-26 |
20150056725 | METHOD FOR PRODUCING A SENSOR - The present invention relates to a method for producing a sensor (SEN), comprising the steps of arranging a sensor element (SE) on a carrier (TR), arranging a cover (AF) on the sensor element (SE), wherein the sensor element (SE) is enclosed between the cover (AF) and the carrier (TR), adhesively bonding a carrier film (TF) onto the cover (AF), and producing an opening (SO) in the carrier film (TF) and the cover (AF), wherein the openings (SO) in the carrier film (TF) and the cover (AF) at least partly overlap. | 2015-02-26 |
20150056726 | CHIP POSITIONING IN MULTI-CHIP PACKAGE - Embodiments of the present invention include a method for multi-chip packaging. For example, the method includes positioning a first integrated circuit (IC) on a substrate package based on a first set of reference markers in physical contact with the substrate package and confirming an alignment of the first IC based on a second set of reference markers in physical contact with the substrate package. A second IC is stacked onto first IC based on the first set of reference markers. An alignment of the second IC is confirmed based on the second set of reference markers, where the second set of reference markers is disposed at a different location on the substrate package than the first set of reference markers. | 2015-02-26 |
20150056727 | METHOD OF INSPECTING SEMICONDUCTOR DEVICE, METHOD OF FABRICATING SEMICONDUCTOR DEVICE, AND INSPECTION TOOL - A method of inspecting a semiconductor device includes attaching an inspection tool on a back surface of a semiconductor substrate including the semiconductor device, the inspection tool including a sheet and a holding frame, the sheet being larger than the semiconductor substrate and being provided with an opening in a center portion of the sheet, the opening being smaller than the semiconductor substrate, the holding frame holding an outer periphery of the sheet, and a supporting substrate being attached on a front surface of the semiconductor substrate, removing the supporting substrate attached on the front surface of the semiconductor substrate, and measuring electrical characteristics of the semiconductor device. | 2015-02-26 |
20150056728 | METHOD REGARDING A LIGHT-EMITTING DIODE FOR WHICH THE ARRANGEMENT OF AN ELECTRODE ON AN EMITTING FACE IS DETERMINED AS A FUNCTION OF THE SPREADING LENGTH OF THE CURRENT IN SAID LIGHT-EMITTING DIODE - The light-emitting diode comprises a first electrode intended to inject carriers of a first type into a stack of the light-emitting diode and arranged on an emissive face of the stack, a second electrode intended to inject carriers of a second type into the stack, and an emissive surface delimited by areas of the emissive face of the stack not covered by the first electrode. The first electrode is configured in such a way that any point of the emissive surface is situated no more than a predetermined distance from the first electrode dependent on the spreading length of the light-emitting diode. The method comprises a step of determining the spreading length of the light-emitting diode intended to be equipped with the first electrode and a step determining a characteristic of the first electrode from the determined spreading length | 2015-02-26 |
20150056729 | METHOD FOR MANUFACTURING SEMICONDUCTOR LIGHT EMITTING APPARATUS AND SEMICONDUCTOR LIGHT EMITTING APPARATUS - A method for manufacturing a semiconductor light emitting apparatus having first semiconductor layer and second semiconductor layer sandwiching a light emitting layer, first and second electrodes provided on respective major surfaces of the first semiconductor and second semiconductor layers to connect thereto, stacked dielectric films having different refractive indexes provided on portions of the major surfaces not covered by the first and second electrodes, and a protruding portion erected on at least a portion of a rim of at least one of the first and second electrodes. The mounting member includes a connection member connected to at least one of the first and second electrodes. The method includes causing the semiconductor light emitting device and a mounting member to face each other, and causing the connection member to contact and join to the at least one of the first and second electrodes using the protruding portion as a guide. | 2015-02-26 |
20150056730 | SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING THE SAME - The present invention relates to a semiconductor device, a manufacturing method thereof. More specifically, this invention is related to a chemical etching method in semiconductor device separation process without using dicing or scribing. | 2015-02-26 |
20150056731 | LIGHT EMITTING REGIONS FOR USE WITH LIGHT EMITTING DEVICES - A light emitting device comprises a first layer having an n-type Group III-V semiconductor, a second layer adjacent to the first layer, the second layer comprising an active material that generates light upon the recombination of electrons and holes. The active material in some cases has one or more V-pits at a density between about 1 V-pit/μm | 2015-02-26 |
20150056732 | SOLID STATE NANOPORE DEVICES AND METHODS OF MANUFACTURE - Solid state nanopore devices for nanopore applications and methods of manufacture are disclosed herein. The method includes forming a membrane layer on an underlying substrate. The method further includes forming a hole in the membrane layer. The method further comprises plugging the hole with a sacrificial material. The method further includes forming a membrane over the sacrificial material. The method further includes removing the sacrificial material within the hole and portions of the underlying substrate. The method further includes drilling an opening in the membrane, aligned with the hole. | 2015-02-26 |
20150056733 | MANUFACTURING METHOD OF MIRCO-ELECTRO-MECHANICAL SYSTEM DEVICE AND MIRCO-ELECTRO-MECHANICAL SYSTEM DEVICE MADE THEREBY - The invention provides a manufacturing method of a MEMS device, which includes: providing an integrated circuit device including a substrate and an electrical structure on the substrate, the electrical structure includes at least one sensing region and at least one first connection section; providing a structure layer, and forming at least one second connection section on the structure layer; bonding the at least one first connection section and the at least one second connection section; etching the structure layer for forming at least one movable structure, the movable structure being located at a position corresponding to a position of the sensing region, and the movable structure being connected to the at least one first connection section via the at least one second connection section; and thereafter, providing a cap to cover the movable structure and the sensing region, wherein the movable structure is not directly connected to the cap. | 2015-02-26 |
20150056734 | METHOD FOR SEPARATION BETWEEN AN ACTIVE ZONE OF A SUBSTRATE AND ITS BACK FACE OR A PORTION OF ITS BACK FACE - A Method for making a separation between an active zone of a substrate located on its front face from a given portion of the substrate located on its back face, wherein trenches and cavities wider than the trenches are formed to extend said trenches, such that at least one given cavity formed to extend a given trench is adjacent to another cavity, and when the cavities have been filled with a given material, they form a separation zone between said active zone and a given portion of the substrate that will be removed later. | 2015-02-26 |
20150056735 | METHOD FOR MANUFACTURING MEMBRANE LAYERS OF ORGANIC SOLAR CELLS BY ROLL TO ROLL COATING - A method for manufacturing membrane layers of organic solar cells by roll to roll coating utilizes a roll to roll process for manufacturing an electron transferring layer and an active layer of the organic solar cells is disclosed. The roll to roll process adopted by the method cooperates with a particular solvent and accompanies a parameter control such as temperature and processing time during the sintering and baking steps. The method utilizes a slot-die coating technique in the interim, whereby a membrane layer of the solar cells can be manufactured with a large area for reducing the cost, and the formed membrane layers can have a good efficiency. | 2015-02-26 |
20150056736 | METHODS OF HERMETICALLY SEALING PHOTOVOLTAIC MODULES - In various embodiments, photovoltaic modules are hermetically sealed by providing a first glass sheet, a photovoltaic device disposed on the first glass sheet, and a second glass sheet, a gap being defined between the first and second glass sheets, disposing a glass powder within the gap, and heating the powder to seal the glass sheets. | 2015-02-26 |
20150056737 | Interconnect Structure for CIS Flip-Chip Bonding and Methods for Forming the Same - A device includes a metal pad at a surface of an image sensor chip, wherein the image sensor chip includes an image sensor. A stud bump is disposed over, and electrically connected to, the metal pad. The stud bump includes a bump region, and a tail region connected to the bump region. The tail region includes a metal wire portion substantially perpendicular to a top surface of the metal pad. The tail region is short enough to support itself against gravity. | 2015-02-26 |
20150056738 | METHOD FOR MANUFACTURING IMAGE SENSOR - A method of manufacturing an image sensor is provided. The method includes forming a photodiode in a pixel area in a first substrate and forming an insulating layer and a metal wire; forming a color filter layer and a microlens on the insulating layer; attaching a cover glass for the microlens to the insulating layer; back-grinding the first substrate to decrease its thickness; forming a via in the first substrate electrically coupled to the metal wire; forming a first microbump on the via; and forming a second microbump on a logic area of a second substrate; and coupling the first and the second microbumps to electrically couple the pixel area to the logic area. | 2015-02-26 |
20150056739 | IMAGE SENSOR TRENCH ISOLATION WITH CONFORMAL DOPING - Provided is a semiconductor image sensor device. The image sensor device includes a substrate. The image sensor device includes a first pixel and a second pixel disposed in the substrate. The first and second pixels are neighboring pixels. The image sensor device includes an isolation structure disposed in the substrate and between the first and second pixels. The image sensor device includes a doped isolation device disposed in the substrate and between the first and second pixels. The doped isolation device surrounds the isolation structure in a conformal manner. | 2015-02-26 |
20150056740 | Process for Fabricating a Ridge Pin Junction Comprising Spaced Apart Doped Regions, Application to the Fabrication of Electro-optical Modulators and Photodetectors - The invention relates to a process for fabricating a semiconductor ridge pin junction ( | 2015-02-26 |
20150056741 | METHOD OF MANUFACTURING SEMICONDUCTOR APPARATUS - A method of manufacturing a semiconductor apparatus comprising forming an electrode on a structure provided on a substrate, the structure including a wiring pattern and an interlayer insulation film, forming a first film covering the electrode and the structure, forming an opening in a portion of the first film inside an outer edge of a convex portion formed by steps between upper faces of the electrode and the structure so as to expose a first portion as a portion of the upper face of the electrode, forming a second film covering the first film and the first portion, forming a protective film covering the first portion, the convex portion, and a periphery of the convex portion by patterning the second film, and forming a third film on the first film and the protective film by spin coating. | 2015-02-26 |
20150056742 | ANNEALING FOR DAMAGE FREE LASER PROCESSING FOR HIGH EFFICIENCY SOLAR CELLS - Annealing solutions providing damage-free laser patterning utilizing auxiliary heating to anneal laser damaged ablation regions are provided herein. Ablation spots on an underlying semiconductor substrate are annealed during or after pulsed laser ablation patterning of overlying transparent passivation layers. | 2015-02-26 |
20150056743 | MANUFACTURING METHOD OF SOLAR CELL - A manufacturing method of a solar cell includes a protection-film forming step of forming a protection film on one surface side of a semiconductor substrate, a first processing step of forming a plurality of first openings having a shape close to a desired opening shape and a size smaller than a target opening size in the protection film by a method having relatively high processing efficiency, a second processing step of forming second openings in the protection film by expanding the first openings up to the target opening size by a method having relatively high processing accuracy, and an etching step of forming an asperity structure having the a concave portion in an inverted pyramid shape on the one surface side of the semiconductor substrate by performing anisotropic wet etching on the semiconductor substrate in a region under the second openings via the second openings. | 2015-02-26 |
20150056744 | THIN FILM STRUCTURES AND DEVICES WITH INTEGRATED LIGHT AND HEAT BLOCKING LAYERS FOR LASER PATTERNING - Selective removal of specified layers of thin film structures and devices, such as solar cells, electrochromics, and thin film batteries, by laser direct patterning is achieved by including heat and light blocking layers in the device/structure stack immediately adjacent to the specified layers which are to be removed by laser ablation. The light blocking layer is a layer of metal that absorbs or reflects a portion of the laser energy penetrating through the dielectric/semiconductor layers and the heat blocking layer is a conductive layer with thermal diffusivity low enough to reduce heat flow into underlying metal layer(s), such that the temperature of the underlying metal layer(s) does not reach the melting temperature, T | 2015-02-26 |
20150056745 | TITANIUM DIOXIDE NANO PARTICLE MODIFIED BY SURFACE STABILIZER, TITANIUM DIOXIDE NANO INK COMPRISING THE SAME, SOLAR CELL EMPLOYING THE SAME, AND PRODUCING METHOD OF THE SAME - Disclosed are a titanium dioxide nano ink having such a strong dispersibility as to be applicable by inkjet printing and having adequate viscosity without requiring printing several times, and a titanium dioxide nano particle modified by a surface stabilizer included therein. Inkjet printing of the titanium dioxide nano ink enables printing of a minute electrode. In addition, efficiency of a solar cell may be maximized since occurrence of pattern cracking is minimized. | 2015-02-26 |
20150056746 | DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC FIELD EFFECT TRANSISTORS - The present invention relates to polymers comprising a repeating unit of the formula I, or III and their use as organic semiconductor in organic devices, especially an organic field effect transistor (OFET), or a device containing a diode and/or an organic field effect transistor. The polymers according to the invention have excellent solubility in organic solvents and excellent film-forming properties. In addition, high efficiency of energy conversion, excellent field-effect mobility, good on/off current ratios and/or excellent stability can be observed, when the polymers according to the invention are used in organic field effect transistors. | 2015-02-26 |
20150056747 | METHOD OF FABRICATING A THIN-FILM DEVICE - A method of forming a thin-film device includes forming an oxide-semiconductor film formed on the first electrical insulator, and forming a second electrical insulator formed on the oxide-semiconductor film, the oxide-semiconductor film defining an active layer. The oxide-semiconductor film is comprised of a first interface layer located at an interface with the first electrical insulator, a second interface layer located at an interface with the second electrical insulator, and a bulk layer other than the first and second interface layers. The method further includes oxidizing the oxide-semiconductor film to render a density of oxygen holes in at least one of the first and second interlayer layers is smaller than a density of oxygen holes in the bulk layer. | 2015-02-26 |
20150056748 | Methods for Forming Resistive Switching Memory Elements by Heating Deposited Layers - Resistive switching nonvolatile memory elements are provided. A metal-containing layer and an oxide layer for a memory element can be heated using rapid thermal annealing techniques. During heating, the oxide layer may decompose and react with the metal-containing layer. Oxygen from the decomposing oxide layer may form a metal oxide with metal from the metal-containing layer. The resulting metal oxide may exhibit resistive switching for the resistive switching memory elements. | 2015-02-26 |
20150056749 | Atomic Layer Deposition of Metal Oxide Materials for Memory Applications - Embodiments of the invention generally relate to nonvolatile memory devices, such as a ReRAM cells, and methods for manufacturing such memory devices, which includes optimized, atomic layer deposition (ALD) processes for forming metal oxide film stacks. The metal oxide film stacks contain a metal oxide coupling layer disposed on a metal oxide host layer, each layer having different grain structures/sizes. The interface disposed between the metal oxide layers facilitates oxygen vacancy movement. In many examples, the interface is a misaligned grain interface containing numerous grain boundaries extending parallel to the electrode interfaces, in contrast to the grains in the bulk film extending perpendicular to the electrode interfaces. As a result, oxygen vacancies are trapped and released during switching without significant loss of vacancies. Therefore, the metal oxide film stacks have improved switching performance and reliability during memory cell applications compared to traditional hafnium oxide based stacks of previous memory cells. | 2015-02-26 |
20150056750 | MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE - A first insulating film in contact with an oxide semiconductor film and a second insulating film are stacked in this order over an electrode film of a transistor including the oxide semiconductor film, an etching mask is formed over the second insulating film, an opening portion exposing the electrode film is formed by etching a portion of the first insulating film and a portion of the second insulating film, the opening portion exposing the electrode film is exposed to argon plasma, the etching mask is removed, and a conductive film is formed in the opening portion exposing the electrode film. The first insulating film is an insulating film whose oxygen is partly released by heating. The second insulating film is less easily etched than the first insulating film and has a lower gas-permeability than the first insulating film. | 2015-02-26 |
20150056751 | DIE EDGE SEALING STRUCTURES AND RELATED FABRICATION METHODS - Die structures for electronic devices and related fabrication methods are provided. An exemplary die structure includes a diced portion of a semiconductor substrate that includes a device region having one or more semiconductor devices fabricated thereon and an edge sealing structure within the semiconductor substrate that circumscribes the device region. In one or more embodiments, the edge sealing structure includes a conductive material that contacts a handle layer of semiconductor material, a crackstop structure is formed overlying the sealing structure, wherein the crackstop structure and the edge sealing structure provide an electrical connection between the handle layer and an active layer of semiconductor material that overlies a buried layer of dielectric material on the handle layer. | 2015-02-26 |
20150056752 | SUBSTRATELESS POWER DEVICE PACKAGES - A substrate-less composite power semiconductor device may be fabricated from a vertical conductive power semiconductor device wafer that includes a top metal layer located on a top surface of the wafer by a) forming solder bumps on top of the top metal layer; b) forming wafer level molding around the solder bumps such that the solder bumps are exposed through a top of the wafer level molding; c) grinding a back side of the device wafer to reduce a total thickness of a semiconductor material portion of the device wafer to a final thickness; and d) forming a back metal on a back surface of the wafer. | 2015-02-26 |
20150056753 | Semiconductor Die Having Fine Pitch Electrical Interconnects - A die has interconnect pads on an interconnect side near an interconnect edge and has at least a portion of the interconnect side covered by a conformal dielectric coating, in which an interconnect trace over the dielectric coating forms a high interface angle with the surface of the dielectric coating. Because the traces have a high interface angle, a tendency for the interconnect materials to “bleed” laterally is mitigated and contact or overlap of adjacent traces is avoided. The interconnect trace includes a curable electrically conductive interconnect material; that is, it includes a material that can be applied in a flowable form, and thereafter cured or allowed to cure to form the conductive traces. Also, a method includes, prior to forming the traces, subjecting the surface of the conformal dielectric coating with a CF | 2015-02-26 |
20150056754 | VACUUM MOLDING APPARATUS, SUBSTRATE PROCESSING SYSTEM HAVING THE SAME AND SUBSTRATE PROCESSING METHOD USING THE SAME - Disclosed herein is a substrate processing system, including: a feeding apparatus which feeds a substrate including a plurality of unit substrates into the substrate processing system; a vacuum molding apparatus which molds the substrate fed by the feeding apparatus; a paste printing apparatus which prints a solder paste on the substrate molded by the vacuum molding apparatus; a mounting apparatus which mounts an electronic device on the substrate on which the solder paste is printed; and a reflow apparatus which performs a reflow on the substrate on which the electronic device is mounted, wherein the vacuum molding apparatus includes a substrate molding control unit which controls the molding of the substrate. Therefore, the warpage (CAW) of the substrate is limitedly formed to improve the warpage (CAW) dispersion of the substrate, thereby improving bonding reliability and a mounting yield between the chip die and the bump of the substrate. | 2015-02-26 |
20150056755 | ELECTRONIC DEVICE PACKAGES HAVING BUMPS AND METHODS OF MANUFACTURING THE SAME - An electronic device package includes a bump having a post disposed on a contact portion of a semiconductor chip and an enlarged portion laterally protruded from an upper portion of the post; an interconnection portion having a locking portion that substantially surrounds the enlarged portion and an upper sidewall of the post; and a dielectric layer substantially surrounding the bump and the locking portion to separate the interconnection portion from the semiconductor chip. | 2015-02-26 |