08th week of 2011 patent applcation highlights part 52 |
Patent application number | Title | Published |
20110046338 | Copolyester polyols, prepolymers, and polyurethane elastomers formed therefrom and processes for making same - Polyurethane elastomers formed from prepolymers derived from copolyester polyols. The copolyester polyols have segments derived from one or more polyesters and caprolactone or polycaprolactone. The polyurethane elastomers have good hardness stability at temperatures ranging from 0° C. to 30° C. and preferably have good hydrolytic stability. | 2011-02-24 |
20110046339 | COPOLYMER CONTAINING 3-HYDROXYALKANOATE UNIT AND LACTATE UNIT, AND ITS MANUFACTURING METHOD - The present invention relates to a copolymer comprising 3-hydroxyalkanoate monomer unit and lactate monomer unit, or their preparing method. More specifically, the present invention relates to a method for preparing a copolymer comprising lactate monomer and 3-hydroxyalkanoate monomer, wherein the method comprises culturing a cell or plant comprising the gene of enzyme converting lactate and 3-hydroxyalkanoate into lactyl-CoA and 3-hydroxyalkanoyl-CoA, respectively, and polyhydroxyalkanoate synthase gene together, and the copolymer made by the method. The copolymer of the present invention is a biodegradable polymer being able to be usefully used instead of conventional synthetic plastic, and the copolymer can be used also for medical use. | 2011-02-24 |
20110046340 | LARGE SCALE PROCESS FOR POLYMERIZATION OF DAPBI-CONTAINING POLYARAMID - A method for obtaining an aromatic polyamide crumb from an aromatic diamine and an aromatic diacid chloride, which aromatic polyamide comprises 5(6)-amino-2-(p-aminophenyl)benzimidazole terephthalamide units and has a relative viscosity η | 2011-02-24 |
20110046341 | BRANCHED COMPOUNDS, ORGANIC THIN FILMS MADE BY USING THE SAME, AND ORGANIC FILM DEVICES - A branched compound including a core part, at least one side chain part bonded to the core part, and an end, wherein one repeating unit or two or more repeating units expressed by the following formula (1) repeat in the or each side chain part, with the proviso that in a repeating unit bonded to the core part, T is bonded to the core part, and in two or more contiguous repeating units, each L is bonded to the T, each L is formed of a plurality of conjugation-forming units linked together; each L includes at least one thienylene unit as the conjugation-forming unit; and at least two of the groups existing at the ends of Ls (the ends of the L in sides which are not bonded to T) are acceptor groups. | 2011-02-24 |
20110046342 | TUMOR SUPPRESSOR ACTIVATING POLYPEPTIDES AND USES THEREOF - Chimeric tumor suppressor activating peptides derived from matrix attachment region binding protein (MARBP) SMARI unique in their sequence comprising a arginine rich motif flanked by serine residues wherein from the stretch of four consecutive serine residues the first serine residue gets phosphorylated by the protein kinase C family of serine threonine kinases being indispensable for its functionality, the phosphorylation being directly correlated to the phosphorylation of p53 at serine 15 residue thereby stabilizing it, wherein the peptide activates p53 by modifying it post translationally which allow phosphorylation and translocation of p53 to the nucleus. | 2011-02-24 |
20110046343 | Primer Array Synthesis and Validation - Methods are presented for generating large sets for polymers. The methods employ high density oligonucleotide array. | 2011-02-24 |
20110046344 | PARALLEL PREPARATION OF HIGH FIDELITY PROBES IN AN ARRAY FORMAT - The present invention provides massively parallel oligonucleotide synthesis and purification for applications that utilize large collections of defined high-fidelity oligonucleotides (e.g., from about 10 | 2011-02-24 |
20110046345 | Methods for preparing linked peptide rings and peptide nanotubes obtained thereby - Peptide nanotube polymers and methods of making such are disclosed. The peptide nanotube polymers comprise of alternating monomers of the first peptide ring and monomers of the second peptide ring covalently bonded to one another via a linker, and can be functionalized. The described peptide nanotube polymers can enjoy the combined properties of healing and toughness, self-reporting, and tunability and actuation. | 2011-02-24 |
20110046346 | BIOMATERIAL WITH FUNCTIONALISED SURFACES - There is provided a biomaterial having a functionalised surface which comprises bi-functional semi-dendrimers. The biomaterial may be ceramic, metallic and/or polymeric. It will usually be in the form of a solid, but could be a semi-solid or hydrogel. There is also provided a method of making a biomaterial having a functionalised surface which comprises bi-functional semi-dendrimers, said method comprising adsorbing, grafting or synthesising in situ bi-functional semi-dendrimers onto the surface of a biomaterial. There is further provided a biomedical device which is coated with or formed from a biomaterial having a functionalised surface which comprises bi-functional semi-dendrimers. The biomedical device may be a medical implant, for example, such as a stent, artificial hip joint or replacement heart valve. FIG. | 2011-02-24 |
20110046347 | DENDRITIC OLIGOPEPTIDE-GRAFTEDED CYCLOTRIPHOSPHAZENE, A PROCESS FOR THE PREPARATION THEREOF AND A DRUG DELIVERY SYSTEM CONTAINING THE SAME - A cyclotriphosphazene represented by Formula 1 prepared by introducing a dendritic tetrapeptide and a hydrophilic polyethylene glycol into a cyclotriphosphazene ring, a method of preparing the same, and a drug carrier including the cyclotriphosphazene of Formula 1. | 2011-02-24 |
20110046348 | METHODS OF PREPARING PEPTIDE DERIVATIVES - The invention relates to methods of preparing peptide hydrazides useful in as intermediates in preparing derivatized peptides and amenable to conversion to reactive azide comprising species. The invention relates to chemical methods of preparing such species from protected peptide-resins containing the aspartyl or glutamyl residues with orthogonal side-chain carboxylic acid protecting groups ester of Asp and Glu. These esters can be selectively converted to the corresponding side-chain hydrazides useful in various synthetic applications | 2011-02-24 |
20110046349 | PROCESS FOR THE PRODUCTION OF EXENATIDE AND OF AN EXENATIDE ANALOGUE - Exenatide, a polypeptide having the 39 amino acid sequence | 2011-02-24 |
20110046350 | LENGTH-ADJUSTABLE NANOSCALE TETHER FOR BINDING TARGETS TO SUBSTRATES - Embodiments of the present invention are directed to reusable, length-adjustable nanoscale tethers that can be incorporated into a variety of different sensors and other electrical, electro-mechanical, electro-optical-mechanical, and optical-mechanical devices. An optionally reusable, length-adjustable nanoscale tether that represents one embodiment of the present invention comprises a binding-structure component, having a substrate-anchor subcomponent and a binding-adapter binding domain, and a binding adaptor that binds to the binding-adapter binding domain and that has a target-binding subcomponent that binds to a target molecule, target particle, or other target entity. The binding-adapter binding domain can be positioned at different distances from the substrate anchor within the binding-structure component so that the distance between a bound target and a sensor substrate can be precisely controlled. | 2011-02-24 |
20110046351 | MUTANT PROTEINS AND METHODS FOR SELECTING THEM - A method for selecting a membrane protein with increased stability, the method comprising: a) providing one or more mutants of a parent membrane protein in a membrane-containing composition, wherein the one or more mutants are exposed to an amount of a membrane destabilising agent which is effective to destabilise the parent membrane protein in-situ, b) determining whether the or each mutant membrane protein has increased stability with respect to its structure and/or a biological activity compared to the stability of the parent membrane protein with respect to its structure and/or the same biological activity, and c) selecting the one or more mutants which have increased stability compared to the stability of the parent membrane protein. | 2011-02-24 |
20110046352 | DISEASE-RESISTANT PLANTS AND METHOD OF CONSTRUCTING THE SAME - The present invention provides transgenic, disease-resistant plants which have been transformed with an expression cassette including a constitutive gene expression promoter; and a gene, under the control of the promoter, encoding a harpin. The transformed cells in the transgenic plant effect the constitutive expression of the harpin in an amount effective for inducing a defense reaction. The harpin is a protein consisting of an amino acid sequence that is at least 90% homologous to the amino acid sequence of SEQ ID NO: 2, and possesses a hypersensitive-response-inducing activity. The present invention also provides methods for producing the transgenic plants, expression cassettes, recombinant vectors and genes encoding harpins. | 2011-02-24 |
20110046353 | Purification Process for Anitbody Fragments Using Derivatized Triazines as Affinity Ligands - A process for the separation of a fragment antibody from a medium is provided. The process comprises contacting the medium comprising the fragment antibody with a synthetic affinity ligand attached to a support matrix under conditions whereby the fragment antibody binds to the synthetic affinity ligand. The synthetic affinity ligand has the formula (I): wherein Q represent an attachment to a solid support matrix, optionally via a spacer group; A and B are each independently —Y-phenyl or —Y-naphthyl groups substituted with one or more substituents capable of hydrogen bonding, preferably one or more of —OH, —SH or —CO | 2011-02-24 |
20110046354 | Humanized High Affinity Recombinant Antibody Against Hepatitis B Surface Antigen - This invention relates to a high affinity recombinant humanized antibody fragment (scFv) specific for hepatitis B surface antigen having unique inter/intra chain bonding interaction because of 28 altered amino acid residues from the original mouse (5S) antibody and its chimeric Fab form, wherein fine tuning of the vernier zone residue makes it closer to the human sequence without any structural constraints. | 2011-02-24 |
20110046355 | CYTOTOXIC IMMUNOGLOBULIN - The invention relates to a cytotoxic modular antibody with a molecular weight of up to 6 OkD, specifically binding to a cell surface target with a binding affinity of Kd<10 | 2011-02-24 |
20110046356 | POST-TRANSLATIONAL MODIFICATIONS AND CLOSTRIDIAL NEUROTOXINS - The present invention discloses modified neurotoxins with altered biological persistence. In one embodiment, the modified neurotoxins are derived from Clostridial botulinum toxins. Such modified neurotoxins may be employed in treating various conditions, including but not limited to muscular disorders, hyperhidrosis, and pain. | 2011-02-24 |
20110046357 | HIGH PRESSURE REFOLDING OF PROTEIN AGGREGATES AND INCLUSION BODIES - The present disclosure provides an effective method for the refolding of denatured proteins in solution so that properly folded, biologically active protein in solution is recovered in high yield. The refolding takes place at pressures between about 0.25 kbar to about 3.5 kbar, advantageously at about 1.5 kbar to about 3 kbar. Typically a chaotropic agent is present at a concentration which is not effective for denaturing protein at atmospheric pressure, and optionally, oxidation-reduction reagents can be incorporated in the refolding solution so that native intramolecular disulfide bonds can be formed where that is desired. The method is applicable to substantially all proteins, especially after solubilization and/or denaturation of insoluble protein aggregates, inclusion bodies, or abnormal oligomeric (soluble) aggregates. | 2011-02-24 |
20110046358 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND - Provided is an easy method for production of a high-performance polyfunctional compound which can be used as an optical recording material, an optical waveguide material, a photo-alignment film material, or the like, in a simple manner. The method for production of a polyfunctional compound includes conducting a Michael addition of a compound (A) having a hydrogen atom of pKa ≦15 to a (meth)acrylate or a (meth)acrylamide (B), in which at least one of the compounds (A) and (B) has a photoisomerization group and/or a liquid-crystalline group. | 2011-02-24 |
20110046359 | REVERSIBLE TERMINATOR NUCLEOTIDES AND METHODS OF USE - Disclosed herein a reversible terminator nucleotides and methods of use. | 2011-02-24 |
20110046360 | ENA NUCLEIC ACID DRUGS MODIFYING SPLICING IN mRNA PRECURSOR - Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides. | 2011-02-24 |
20110046361 | METHOD FOR SEPARATION OF DOUBLE-STRANDED AND SINGLE-STRANDED NUCLEIC ACIDS - The invention provides systems, methods and kits for the separation and/or purification of double-stranded and single-stranded nucleic acids. The method includes first mixing a sample containing the double-stranded nucleic acid and the single-stranded nucleic acid with a pH-neutral, buffered solution consisting essentially of a chaotropic salt and a pH buffer to generate a mixture; then applying the mixture to a first mineral support for the double-stranded nucleic acid to bind; and collecting the flow-through which contains unbound single-stranded nucleic acid. The method further includes adjusting the pH of the flow-through to an acidic pH, and applying the acidified flow-through to a second mineral support for the single-stranded nucleic acid to bind. Alternatively the flow-through can be mixed with a lower aliphatic alcohol prior to loading of the second column. The double-stranded and the single-stranded nucleic acids bound can be eluted from the mineral supports respectively. | 2011-02-24 |
20110046362 | METHODS OF MAKING NUCLEOSIDE TETRAPHOSPHATE - The invention provides compounds and methods for making adenosine-ribofuranoside tetraphosphate compounds. The compounds are contemplated to have activity at the P2Y receptor and may be used in the treatment of medical disorders such as cystic fibrosis and upper respiratory disorders. | 2011-02-24 |
20110046363 | Process for the Preparation of Cladribine - A process for the preparation of cladribine of API grade is provided by direct coupling of O-protected 2-deoxy-ribofuranose with silylated 2-chloroadenine followed by deprotection of the resultant protected nucleoside in a separate step and then a purification step. Following the coupling, the desired N-9-glycosylated β-anomer of the nucleoside is directly isolated as a solid from the coupling reaction mixture by filtration in relatively high purity and yield, and it does not require purification. | 2011-02-24 |
20110046364 | METHOD OF LABELING SUGAR CHAIN - The present invention relates to a method of labeling a sugar chain, used for labeling a sugar chain contained in a biological sample, aimed at simplifying a process of isolating a sugar chain from a biological sample and labeling it, which includes (a) trapping a sugar chain in a sugar-trapping substance, which is a substance for specifically trapping a sugar chain from a biological sample; (b) washing the sugar-trapping substance having the sugar chains trapped thereon; (c) releasing the sugar chain from the sugar-trapping substance; and (d) labeling the released sugar chain, | 2011-02-24 |
20110046365 | CELLULOSE DERIVATIVES, METHOD OF PRODUCING THE SAME AND USE THEREOF - A transglycosylation product, a method of producing the same and use of the product. The transglycosylation product comprises an alkyl or hydroxyalkyl glycoside of a cellulose ester or ether, wherein the alkyl or hydroxyalkyl groups of the glycoside residue comprise a carbon chain having 1 to 4 carbon atoms, and having 0 to 2 free hydroxyl groups and being attached to the 1-carbon of the anhydroglucose unit via an oxy group. The product can be produced by mixing the cellulose derivative with mono-, di- or triol to form a reaction mixture, after which the reaction mixture is heated and the reaction is continued until a clear mixture is obtained. After cooling the recoverable product is suitable for use for example as an adhesive or as a hydrophobic coating. | 2011-02-24 |
20110046366 | LIQUID PORPHYRIN DERIVATIVE, AND METHOD FOR PRODUCING THE SAME - The present invention is to provide a liquid porphyrin derivative at 25° C. and at temperatures from 26 to 40° C., and a method for producing the same. The liquid porphyrin derivative of the present invention is represented by the following formula (1): | 2011-02-24 |
20110046367 | 3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION - Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described. | 2011-02-24 |
20110046368 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF - The invention relates to novel ligands of 5-HT | 2011-02-24 |
20110046369 | METHOD FOR PREPARING ADENINE COMPOUND - A method for producing adenine compound (1): | 2011-02-24 |
20110046370 | 1,3,6-SUBSTITUTED INDOLE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE - Disclosed are a 1,3,6-substituted indole compound having inhibitory activity for protein kinases, a pharmaceutically acceptable thereof, and a pharmaceutical composition for prevention and treatment of diseases caused by abnormal cell growth including the compound as an active ingredient. | 2011-02-24 |
20110046371 | PROCESS FOR PREPARING 2-(AMINOMETHYLIDENE)-4,4-DIFLUORO-3-OXOBUTYRIC ESTERS - The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters, 2-(aminomethylidene)-4,4-difluoro-3-oxobutteric esters of the formula (I) | 2011-02-24 |
20110046372 | NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME - The present invention provides novel boron compounds which are useful, depending on their characteristics, as light-emitting materials, electron-transport materials, electron-injection materials, hole-blocking materials, or organic semiconductor materials, and which have new molecular structures quite different from those of the heretofore known boron compounds; their production processes; and functional electronic devices using the same. The novel boron compounds are, for example, those of the following formula (1): | 2011-02-24 |
20110046373 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION - The present invention provides with a process of preparing an optically active succinimide derivative, which is a key intermediate for production of ranirestat. A compound (3) is easily prepared by treating the derivative of succinic acid diester of the formula (2): | 2011-02-24 |
20110046374 | Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These - The present invention relates to pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, methods for their production and doped organic semiconductor material which use such quinazolines. | 2011-02-24 |
20110046375 | ((2S,4R)-4,6-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YL)METHYL CARBOXYLATE AND PROCESS FOR THE PRODUCTION THEREOF - The present invention relates to ((2S,4R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl)methyl carboxylates and a process for the production thereof. Furthermore, the present invention relates to a process for the production of statins and in particular of Rosuvastatin and derivates thereof, wherein the above mentioned compounds are used as intermediates. | 2011-02-24 |
20110046376 | METHODS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS. - A method for synthesizing a heterocyclic compound includes: reacting 1-methylpiperazine with 5-chloro-2-nitroaniline at an internal temperature sufficient to provide a compound of Formula VIH The 1-methylpiperazine and the 5-chloro-2-nitroaniline are reacted in a solvent that comprises water in an amount greater than 50 percent by volume based on the amount of the solvent and/or are reacted in a solvent that comprises an organic solvent component that has a boiling point of greater than 100° C. at atmospheric pressure. | 2011-02-24 |
20110046377 | TETRAHYDROPYRIDOETHERS FOR TREATMENT OF AMD - A medication comprising tetrahydropyridoethers for use in the treatment of AMD. | 2011-02-24 |
20110046378 | Novel Imaging Agents for Detecting Neurological Dysfunction - Disclosed here in are compounds and methods of diagnosing Alzheimer's Disease or a predisposition thereto in a mammal, the method comprising administering to the mammal a diagnostically effective amount of a radiolabeled compound, wherein the compound is selected from the group consisting of radiolabeled flavones, coumarins, carbazoles, quinolinones, chromenones, imidazoles and triazoles derivatives, allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing Alzheimer's Disease | 2011-02-24 |
20110046379 | Quinoline Compounds, Intermediates, Preparation Methods and Uses Thereof - A kind of quinoline compounds as formula A, pharmaceutical accepted solvates, optical isomers or polymorphisms thereof. The intermediates of formula D. in which, R | 2011-02-24 |
20110046380 | METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND - A method for producing an unsaturated organic compound represented by the formula (3): | 2011-02-24 |
20110046381 | NOVEL 4-{3-[4-(3-{4-[AMINO (BUTOXYCARBONYLIMINO) METHYL] PHENOXY} PROPYL)-1-PIPERIDINYL] PROPOXY]-N'-(BUTOXYCARBONYL) BENZAMIDINE CRYSTALS - Problems To provide novel crystals of 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}-N′-(butoxycarbonyl)benzamidine. | 2011-02-24 |
20110046382 | PROCESS FOR THE PREPARATION OF 4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]NITROBENZENE AND PIOGLITAZONE - A process for the preparation of 4-[2-(5-ethyl-2-pyridyl)ethoxy]nitrobenzene is described, which comprises the step of reacting 2-(5-ethyl-2-pyridyl)ethanol with 1-fluoro-4-nitrobenzene in acetone in the presence of an alkali metal hydroxide. The intermediate 4-[2-(5-ethyl-2-pyridyl)ethoxy]nitrobenzene is used for the preparation of pioglitazone. | 2011-02-24 |
20110046383 | CRYSTALLINE S-OMEPRAZOLE STRONTIUM HYDRATE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME - Disclosed are a crystalline S-omeprazole strontium hydrate for the prevention or treatment of gastric acid-related diseases, which has high optical purity, theremostability, solubility and nonhygroscopicity, a method for preparing same, and a pharmaceutical composition containing same. | 2011-02-24 |
20110046384 | PROCESS FOR PREPARATION OF E-ISOMER OF 1-(4-METHYLPHENYL) - 1-(2-PYRID YL)-3-PYRROLIDINO PROP-1-ENE AND ACID ADDITION SALTS THEREOF - A process for preparation of E-isomer of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene of Formula-I, and acid addition salts thereof, said process comprising; dehydrating 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinopropan-1-ol of Formula III followed by adding a base solution to obtain a mixture of E and Z isomers of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene, and washing said mixture of E and Z isomers of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene with water to dissolve Z isomer and to obtain E-isomer of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene of Formula I, which is substantially free from Z isomer. | 2011-02-24 |
20110046385 | Polymorphs Of Prostaglandin Agonists And Methods For Making The Same - The present invention relates to polymorphic crystalline forms or a non-crystalline form or amorphous of the compound (3-(((4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino)-methyl)-phenoxy)-acetic acid sodium salt or a hydrate thereof together with processes for preparing, methods for using, and pharmaceutical compositions containing the same. The invention also relates to substantially pure polymorphic crystalline forms or a non-crystalline form or amorphous form of (3-(((4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino)-methyl)-phenoxy)-acetic acid sodium salt or a hydrate thereof. | 2011-02-24 |
20110046386 | PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME - The present invention provides a novel dinuclear platinum(II) complex compound that can bind to DNA by a mode different from that of cisplatin-type drugs, a method of producing this compound and an anticancer agent comprising this compound as an effective component. This compound is a tetrazolato-bridged platinum complex compound represented by the following formula (I), wherein A is optionally substituted tetrazolato, B is an inorganic or organic anion, and m and n are integers determined in accordance with the charge number of the platinum complex ion and the charge number of the anion. | 2011-02-24 |
20110046387 | 5-ARYL-4-(5-SUBSTITUTED 2,4-DIHYDROXYPHENYL)-1,2,3-THIADIAZOLES AS INHIBITORS OF HSP90 CHAPERONE AND THE INTERMEDIATES FOR PRODUCTION THEREOF - Invention is related to novel compounds -5-aryl-4-(5-substituted 2,4-dihydroxyphenyl)-1,2,3-thiadiazoles with general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit Hsp90 chaperone which participate in cancer progression. This invention is also related to new intermediate compounds which are used for the synthesis of thiadiazoles of general formula (I). | 2011-02-24 |
20110046388 | Crystalline forms of thiazolidinedione compound and its manufacturing method - It is an object of the present invention to provide the crystalline form of a thiazolidinedione compound, which is effective as a pharmaceutical ingredient for manufacturing a peroxisome proliferator-activated receptor (PPAR) activator and an anticancer pharmaceutical composition. The present invention relates to a crystalline form of a hydrate of 5-(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1-H benzimidazol-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione dihydrochloride represented by the following formula (I). [Formula 1] | 2011-02-24 |
20110046389 | INTERMEDIATES FOR THE PREPARATION OF (3R, 4S)-1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL)]-4-(4-- HYDROXYPHENYL)-2-AZETIDINONE - A method for the preparation of (S)-alcohol oxazolidides of general formula II, in which PG represents hydrogen or a hydroxyl protecting group, such as trimethylsilyl, tert-butyldimethylsilyl, benzyloxycarbonyl, tert-butoxycarbonyl, benzyl, benzhydryl or trityl, in which a ketal oxazolidide of general formula III, where PG has the same meaning as above and R means an alkyl with 1-4 carbon atoms, linear or branched, such as methyl, ethyl, isopropyl or butyl, or R+R together represents a divalent alkyl, or substituted with 1 or 2 alkyl groups, e.g. 1,2-ethylene, 1,2-propylene, 1,2-butylene, 1,3-propylene or 2,2-dimethyl-1,3-propylene, is deprotected by the action of acidic reagents in a mixture of water and a water-miscible solvent in the temperature range of 0 to 100° C. (stage A), and the obtained ketone oxazolidide of general IV, in which PG has the same meaning as above, is reduced with asymmetrical reagents in an inert organic solvent in the temperature range of −30 to +40° C. (stage B). | 2011-02-24 |
20110046390 | Gas Generant Compositions - A novel compound, used for example, as a gas generating fuel, is defined as a compound having the structural formula of R | 2011-02-24 |
20110046391 | PROCESS FOR PREPARING EPROSARTAN MESYLATE - The present invention discloses a process for preparing eprosartan mesylate, in which eprosartan is dissolved or suspended in glacial acetic acid, then methanesulfonic acid is added and a solution of eprosartan mesylate in glacial acetic acid is obtained by stirring, a solid of eprosartan mesylate is precipitated by continuously stirring and then obtained by filtration, or a solid of eprosartan mesylate is obtained by concentrating the glacial acetic acid to dry, or a solid of eprosartan mesylate is obtained by adding dropwise an organic ester solvent into the glacial acetic acid under stirring to precipitate a crystal and separate the crystal. | 2011-02-24 |
20110046392 | Oxo-titanylphthalocyanine crystal, method for producing the same, and electrophotographic photoreceptor - The invention provides an oxo-titanylphthalocyanine crystal which is stable, is superior in dispersibility in a photoreceptive layer and efficiently contributes to improvements in sensitivity and charge retention rate of an electrophotographic photoreceptor when it is used as a charge generating agent, a method for producing the oxo-titanylphthalocyanine crystal, and an electrophotographic photoreceptor. The oxo-titanylphthalocyanine crystal has predetermined optical characteristics and thermal properties and is produced by a production method including the following steps (a) to (d): (a) a step of dissolving a crude oxo-titanylphthalocyanine crystal in an acid to obtain an oxo-titanylphthalocyanine solution; (b) a step of adding the oxo-titanylphthalocyanine solution dropwise in a poor solvent to obtain a wet cake; (c) a step of washing the wet cake with an alcohol having 1 to 4 carbon atoms; and (d) a step of stirring the washed wet cake under heating in a nonaqueous solvent to obtain an oxo-titanylphthalocyanine crystal. | 2011-02-24 |
20110046393 | PROCESS FOR PRODUCING TRANS-DIBENZOXENOPYRROLE COMPOUND AND INTERMEDIATE THEREFOR - The invention provides a process for production of trans-dibenzoxenopyrrole compounds, in which reduction, leaving group conversion, hydrogenation and methylation are carried out in that order. The process of the invention allows trans-dibenzoxenopyrrole compounds to be produced by a simpler procedure than conventional processes. The invention further provides novel compounds obtained as intermediates in the process, and a process for their production. | 2011-02-24 |
20110046394 | Pharmaceutical Process and Intermediates 714 - The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): | 2011-02-24 |
20110046395 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE - The present invention relates to a process for the manufacture of the compound 4-[(Z)-[[4-[(dimethylamino)methyl]phenyl]amino](6-fluoro-1,2-dihydro-2-oxo-3H-in-dol-3-ylidene)methyl]-benzenepropanoic acid and to a new intermediate for the synthesis. | 2011-02-24 |
20110046396 | POLYMORPHIC FORMS OF FLUVASTATIN SODIUM AND PROCESS FOR PREPARING THE SAME - Disclosed herein are novel polymorphic forms of Fluvastatin sodium, wherein said polymorphic forms are designated as J | 2011-02-24 |
20110046397 | NEW PROCESSES - The invention relates to a new process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according to the present invention, are ultimately related to the synthesis of intermediates to prepare the above NEP inhibitors, namely compounds according to formula (1), or salt thereof, | 2011-02-24 |
20110046398 | INTERMEDIATES IN THE SYNTHESIS ZEARALENONE MACROLIDE ANALOGS - Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV), wherein R | 2011-02-24 |
20110046399 | PROCESS FOR PREPARING A HYDROXYACID OR HYDROXYESTER - A process for preparing a hydroxyacid or hydroxyester from a reactant selected from
| 2011-02-24 |
20110046400 | PREPARATION METHOD OF (3S,4S)-3-HEXYL-4-((R)-2-HYDROXYTRIDECYL)-OXETAN-2-0NE AND THE PRODUCT OF THAT METHOD - The present invention relates to a method for the preparation of (3S,4S)-3-hexyl-4-((R)-2-hydroxytridecyl)-oxetan-2-one and a product of the method. The method includes the following steps: a) reducing a substance represented by formula (II) to obtain a substance represented by formula (III), and then oxidizing the substance represented by formula (III) to form a substance represented by formula (IV); b) acylating n-octanoic acid to obtain n-octanoyl chloride using thionyl dichloride, then condensing the obtained n-octanoyl chloride with 2-mercapto-pyridine under basic condition to form a substance represented by formula (V), and then converting the substance represented by formula (V) to a substance represented by formula (VI); c) reacting the substance obtained in the step a) with the substance obtained in the step b) under catalytic condition of Lewis acid to generate a substance represented by formula (VII), and then reacting with a Lewis acid. The meanings of the signs in these formulas are the same as those in the description. | 2011-02-24 |
20110046401 | PROCESS FOR PREPARING GLYCIDYL ESTERS - Process for preparing glycidyl esters, wherein carbonate esters of the formula I | 2011-02-24 |
20110046402 | NOVEL METHOD AND INTERMEDIATES FOR PREPARING 19-NORSTEROID COMPOUNDS - The subject of the invention is a method for preparing compounds of general formula (I): | 2011-02-24 |
20110046403 | PROCESS FOR SYNTHESIZING ORGANIC/INORGANIC COMPOSITE - The present invention is characterized in that it is a process for synthesizing an organic/inorganic composite that not only comprises an oxide of silicon and metal, oxide which includes a bond being expressed by “M-O-M” (where “M” independently represents silicon atom or metal atom), but also possesses an organic group which is bonded to a part of silicone atoms at least; and it includes: a preparation step of preparing a raw-material solution by dissolving an organo alkoxysilane, which possesses one or more alkoxy groups and has the silicon atom that is bonded with the organic group by covalent bond, and a metallic compound, which includes the metal atom, in a first solvent, which is a polar solvent; a reaction step of synthesizing the organic/inorganic composite by not only hydrolyzing the organo alkoxysilane and the metallic compound but also condensing them by means of dehydration; and a removal step of adding a second solvent, which does not dissolve compatibly with a solution that has undergone the reaction step, to the solution, thereby dissolving the organic/inorganic composite in the second solvent, and thereafter removing another solution, which does not dissolve compatibly with the second solvent. It is possible to recover the organic/inorganic composite readily by means of the present synthesizing process. | 2011-02-24 |
20110046404 | PROCESS FOR PRODUCING NANOPARTICLES - A process comprises (a) combining (1) at least one metal cation source, (2) at least one phosphate anion source, (3) at least one organic base comprising at least one organic moiety comprising at least about five carbon atoms, and (4) at least one organosilane comprising at least one organic moiety comprising at least about six carbon atoms; and (b) allowing the metal cation source and the phosphate anion source to react in the presence of the organic base and the organosilane (for example, to form surface-modified metal phosphate nanoparticles). | 2011-02-24 |
20110046405 | METHOD FOR THE AQUEOUS TREATMENT OF AN AMINO-FUNCTIONAL ORGANOSILANE CONTAINING AMMONIUM HALIDES AND/OR ORGANIC AMINE HYDROHALIDES - The invention relates to a method for the treatment of an amino functional organosilane containing ammonium halides and/or organic amine hydrohalides, wherein at least one non-polar organic solvent is optionally added to the amino functional organosilane containing the ammonium halides and/or organic amine hydrohalides, an aqueous lye is added. The mixture is reacted and subsequently the aqueous phase is separated from the organic phase, the solvent contained in the organic phase is removed from said phase and the residual organic phase is recovered. | 2011-02-24 |
20110046406 | PROCESS FOR THE PREPARATION OF (S)-2-AMINO-5-CYCLOPROPYL-4,4-DIFLUOROPENTANOIC ACID AND ALKYL ESTERS AND ACID SALTS THEREOF - The present invention relates to a process for the preparation of alkyl esters of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)-N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-difluoro-2-(S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanamide and related compounds, which are compounds that are cysteine protease inhibitors. | 2011-02-24 |
20110046407 | PROCESS FOR PREPARING ALKOXYAMINES RESULTING FROM BETA-PHOSPHORATED NITROXIDES - The invention relates to an improved process for preparing alkoxyamines resulting from β-phosphorated nitroxides corresponding to the formula (I): | 2011-02-24 |
20110046408 | GELLED HYDROCARBONS FOR OILFIELD PROCESSES, PHOSPHATE ESTER COMPOUNDS USEFUL IN GELLATION OF HYDROCARBONS AND METHODS FOR PRODUCTION AND USE THEREOF - Phosphate esters useful for gelling hydrocarbons in combination with a metal source are disclosed along with methods of preparation of the phosphate esters. Fouling in oil refinery towers has been attributed due to distillation of impurities present in phosphate esters used to gel hydrocarbons for oil well fracturing. The improved method of preparation of the phosphate ester results in a product that substantially reduces or eliminates volatile phosphorus, which is phosphorus impurities that distill up to 250° C., and increases the high temperature viscosity of the hydrocarbon gels formed using the phosphate esters. | 2011-02-24 |
20110046409 | PROCESS FOR CONTINUOUS PRODUCTION OF ORGANIC CARBONATES OR ORGANIC CARBAMATES AND SOLID CATALYSTS THEREFORE - Processes for the alcoholysis, inclusive of transesterification and/or disproportionation, of reactants are disclosed. The alcoholysis process may include feeding reactants and a trace amount of soluble organometallic compound to a reactor comprising a solid alcoholysis catalyst, wherein the soluble organometallic compound and the solid alcoholysis catalyst each independently comprise a Group II to Group VI element, which may be the same element in various embodiments. As an example, diphenyl carbonate may be continuously produced by performing transesterification over a solid catalyst followed by disproportionation, where a trace amount of soluble organometallic compound is fed to the transesterification reactor. Also disclosed is a process for reactivating a spent solid alcoholysis catalyst, such as a catalyst useful for transesterifications and/or disproportionations, the process including removing polymeric materials deposited on the catalyst and re-depositing catalytically active metals on the solid catalyst. | 2011-02-24 |
20110046410 | Method for Producing Caffeic Acid Phenyl Ester and Its Analogues - A method for producing caffeic acid phenyl ester and its analogues, which includes the steps of: (i) reacting, in a solvent, a salt of a compound of formula (II) | 2011-02-24 |
20110046411 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF STATIN DERIVATIVES - The invention relates to novel synthesis methods for the preparation of statin derivatives, which methods proceed by way of a key intermediate of formula I | 2011-02-24 |
20110046412 | Sulfonation of Polyhydroxyaromatics - The present invention provides improved process for the sulfonation of hydroxyaromatics amenable to direct isolation of the sulfonylated hydroxyaromatics in their free-acid forms. The process allows for the recyclization of sulfuric acid and minimizes waste. The starting materials are from a renewal resource, e.g., biomass, and contain detectable | 2011-02-24 |
20110046413 | PROCESS FOR PREPARING 4-PENTENOIC ACID - The present invention relates to a process for preparing 4-pentenoic acid, at least comprising the oxidation of a mixture (G) comprising 4-pentenal, 3-methyl-2-butanone and cyclopentene oxide, and to the use of a mixture (G) comprising 4-pentenal, 3-methyl-2-butanone and cyclopentene oxide for preparing 4-pentenoic acid. In the context of the present invention, the mixture (G) is preferably obtained as a by-product of the oxidation of cyclopentene to cyclopentanone by means of dinitrogen monoxide. | 2011-02-24 |
20110046414 | Photo-reaction of tyrosine with cetyltrimethylamonium chloride and nitrogen containing functional groups - A photo-reaction of tyrosine (and small tyrosyl peptides) with cetyltrimethylamonium chloride in aqueous buffer solution is described in this patent. The reactants were exposed to simulated sun irradiance of 760 W/m | 2011-02-24 |
20110046415 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOALKYLIDENEBISOXAZOLINE COMPOUND AND INTERMEDIATE THEREOF - It is provided to an optically active cycloalkylidenebisamidoalcohol compound represented by the formula (3): | 2011-02-24 |
20110046416 | PROCESS FOR PREPARATION OF BENZPHETAMINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS - The present invention provides a simple method for preparation of benzphetamine and its acid addition salt comprising reaction of methamphetamine hydrochloride of formula (III) with benzyl chloride and treating the isolated benzphetamine of formula (II) with an acid dissolved in an organic solvent to provide benzphetamine acid addition salt, more specifically, benzphetamine hydrochloride of formula (I). | 2011-02-24 |
20110046417 | PROCESS FOR PRODUCTION OF ALKOXYCARBONYL COMPOUND - A method for producing an alkoxycarbonyl compound wherein the method comprises reacting carbon monoxide and an alcohol compound with methylacetylene in the presence of a catalyst containing a Group 10 metal compound, a proton acid and a phosphine compound, the propadiene content of the methylacetylene is 50 ppm or less, the phosphine compound is used at greater than 0.000020 mol with respect to 1 mol of methylacetylene, and the carbon monoxide and the alcohol compound are reacted with 200000 mol or more of methylacetylene with respect to 1 mol of the Group 10 metal compound. | 2011-02-24 |
20110046418 | METHOD FOR PRODUCING HYDROGENOLYSIS PRODUCT OF POLYHYDRIC ALCOHOL - The present invention relates to a process for producing a hydrogenolysis product of a polyhydric alcohol in the presence of a catalyst in which a conversion rate of the polyhydric alcohol as well as a selectivity to the hydrogenolysis product, in particular, a selectivity of glycerol to propanediols, can be enhanced. The process for producing a hydrogenolysis product of a polyhydric alcohol according to the present invention includes the step of subjecting a polyhydric alcohol solution having a water content of less than 10% by mass to hydrogenolysis by a fixed-bed continuous liquid phase reaction method in the presence of a hydrogenolysis catalyst. | 2011-02-24 |
20110046419 | METHOD FOR PRODUCING ETHYLENE GLYCOL FROM POLYHYDROXY COMPOUND - A method for producing ethylene glycol, including (a) adding a polyhydroxy compound and water to a sealed high-pressure reactor, (b) removing air and introducing hydrogen, and (c) allowing the polyhydroxy compound to react in the presence of a catalyst while stiffing. The catalyst includes a first active ingredient and a second active ingredient. The first active ingredient includes a transition metal of Group 8, 9, or 10 selected from iron, cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum, and/or a mixture thereof. The second active ingredient includes a metallic state of molybdenum and/or tungsten, or a carbide, nitride, or phosphide thereof. The method is carried out at a hydrogen pressure of 1-12 MPa, at a temperature of 120-300° C. for not less than 5 min in a one-step catalytic reaction. The efficiency, selectivity, and the yield of ethylene glycol are high. The preparation process is simple and the materials used are renewable. | 2011-02-24 |
20110046420 | PROCESS FOR THE CO-PRODUCTION OF ALCOHOLS - The present invention relates to the co-production of unsaturated aldehydes via a crossed-aldol condensation reaction catalyzed by recyclable water-soluble phase-transfer catalysts or the hydroxides thereof. The aldehydes are then hydrogenated to the desired alcohol products or saturated aldehyde feed stocks. Specifically, methods in which 2,4-diethyloctanol is co-produced with 2-ethylhexanol in batch and continuous processes are described. Recovery of the phase-transfer catalyst through water washing followed by “salting out” from the washings is also demonstrated. | 2011-02-24 |
20110046421 | PROCESS FOR THE PRODUCTION OF ALCOHOL FROM A CARBONACEOUS FEEDSTOCK - The present invention relates to a process for the production of ethanol from a carbonaceous feedstock, wherein the carbonaceous feedstock is first converted to synthesis gas which is then converted to ethanoic acid, which is then subject to a two stage hydrogenation process by which at least a part of the ethanoic acid is converted by a primary hydrogenation process to ethyl ethanoate, which ethyl ethanoate is converted by a secondary hydrogenation process to produce ethanol. | 2011-02-24 |
20110046422 | FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES - The invention provides for methods, compositions and systems using bioisoprene derived from renewable carbon for production of a variety of hydrocarbon fuels and fuel additives. | 2011-02-24 |
20110046423 | HYDROTREATING CARBOHYDRATES - Conversion of renewable hydrocarbons to transportation fuels is required to reduce carbon emission, limit the use of fossil fuels, and develop renewable energy sources. Sorbitol, xylitol and trehelose are polyalcohols generated from the liquefaction of various sugars and carbohydrates in biomass from algae, corn, sugarcane, switchgrasses, and biological wastes. Mixtures of aqueous polyols and fuel feedstocks are catalyzed over metal catalysts to produce hexanes, pentanes, and lighter hydrocarbons. By managing the catalyst, reaction conditions and sulfur content, the octane value of the product fuel is dramatically increased. | 2011-02-24 |
20110046424 | PROCESS FOR THE PREPARATION OF HYDROGENATED HYDROCARBON COMPOUNDS - A process for the dehydrogenation of a paraffinic hydrocarbon compound, such as an alkane or alkylaromatic hydrocarbon compound to produce an unsaturated hydrocarbon compound, such as an olefin or vinyl aromatic compound or mixture thereof, in which a dehydrogenation catalyst contacts gaseous reactant hydrocarbons in a reactor at dehydrogenation conditions. | 2011-02-24 |
20110046425 | BATCH PROCESS AND SYSTEM FOR THE PRODUCTION OF OLEFINS - Disclosed herein is a process for producing an alpha olefin comprising obtaining a feed stream comprising an internal olefin having a first carbon number and an alpha olefin having a first carbon number, isomerizing the feed stream to increase the quantity of the alpha olefin, fractionating, subjecting the overhead material from fractionation to catalytic metathesis to produce a mixed olefin effluent comprising an internal olefin having a second carbon number and other hydrocarbons, fractionating, preparing the first isomerization reactor and fractionator to receive the olefin having a second carbon number, isomerizing the internal olefin intermediate in the prepared first isomerization reactor, and fractionating the second isomerization effluent in the prepared first fractionator to separate the alpha olefin having the second carbon number from the internal olefin having the second carbon number. A corresponding system also is disclosed, along with a heat pump that can be incorporated into the process. | 2011-02-24 |
20110046426 | METHOD FOR CONTINUOUS CONVERSION OF METHANOL TO HIGHER HYDROCARBONS AND CATALYST USED THEREIN - Methods and apparatuses for converting methanol to higher hydrocarbons in a continuous process. A distillation column may be packed with inert material and filled with an ionic liquid. The ionic liquid may function as both reaction medium and catalyst. Derivative of zinc iodide and indium iodide may serve as the possible catalytic species. Higher hydrocarbons may be isolated from reaction effluent by condensation in a cold-water condenser, a cold trap, or both. | 2011-02-24 |
20110046427 | XYLENE PRODUCTION PROCESSES WITH INTEGRATED FEEDSTOCK TREATMENT - A process for aromatic transalkylation and olefin reduction of a feed stream is disclosed. Transalkylation conditions provide a product having increased xylene concentration and reduced olefin concentration relative to the feed. The process may be used in a xylene production facility to minimize or avoid the necessity of feedstock pretreatment such as hydrotreating, hydrogenation, or treating with clay and/or molecular sieves. | 2011-02-24 |
20110046428 | Methods of Isomerizing Xylenes with a Catalyst Reduced in the Presence of Hydrogen and a Base - A xylene isomerization process includes introducing gas comprising hydrogen and a base to a reaction zone in which a catalyst comprising a Group VIII metal and a zeolite support resides. In one embodiment, the base may be formed in situ within the reaction zone from nitrogen and hydrogen that are introduced to the reaction zone. In another embodiment, the base is introduced directly to the reaction zone. The conditions in the reaction zone are effective to reduce the catalyst. A stream comprising C | 2011-02-24 |
20110046429 | Method for preparing linear alpha-olefins - The present invention relates to a method for preparing linear alpha-olefins (LAO) by oligomerization of ethylene in the presence of solvent and homogenous catalyst, comprising the steps of: (i) feeding ethylene, solvent and catalyst into an oligomerization reactor, (ii) oligomerizing the ethylene in the reactor, (iii) removing a reactor outlet stream comprising solvent, linear alpha-olefins, ethylene, and catalyst from the reactor via a reactor outlet piping system, (iv) transferring the reactor outlet stream to a catalyst deactivation and removal step, and (v) deactivating and removing the catalyst from the reactor outlet stream, characterized in that at least one organic amine is added into the oligomerization reactor and/or into the reactor outlet piping system. | 2011-02-24 |
20110046430 | METAL REMEDIATION USING A MESOPOROUS NANOCOMPOSITE - A novel method for remediating metals includes treating the metals with a mesoporous nanocomposite such as HMS, MCM-41 or MCM-48. The metal is preferably lead but can be at least one metal selected from Pb, Hg, Cd, Zn, Sn, As, Sb, In, Se, Ga, Te, Bi, Ni, Cu, Mo, Ni, Cu, Sr, Ba or Co. The treating is preferably performed at a pH of about 4 to about 12. In the invention, the treating can also include desorbing the metal from the mesoporous nanocomposite at a pH of about 2 or less. | 2011-02-24 |
20110046431 | APPARATUS, COMPOSITION, AND METHOD TO REMEDIATE AN ACID AND/OR LIQUID SPILL - A method and apparatus to remediate a release of caustic materials or acidic materials by supplying a poly(acrylic acid-co-acrylamide) and disposing that poly(acrylic acid-co-acrylamide) onto a liquid spill comprising caustic materials or acidic materials. | 2011-02-24 |
20110046432 | NON-INVASIVE TREATMENT OF BRONCHIAL CONSTRICTION - Devices, systems and methods are disclosed for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease. The treatment comprises transmitting impulses of energy non-invasively to selected nerve fibers that are responsible for smooth muscle dilation. The transmitted energy impulses, comprising magnetic and/or electrical, mechanical and/or acoustic, and optical and/or thermal energy, stimulate the selected nerve fibers. | 2011-02-24 |
20110046433 | METHOD AND APPARATUS FOR CONTROLLING TEMPERATURE IN A WARMING THERAPY DEVICE - An apparatus and method for performing warming therapy is described, In one exemplary embodiment, the apparatus includes a patient support assembly and a hood adapted to cover a portion of the patient support assembly, where the hood is comprised of at least one side wall which includes at least one thermoelectric element. The thermoelectric element may be controlled by a current source to effect heating and cooling of a patient disposed on the patient support assembly. | 2011-02-24 |
20110046434 | SYSTEM FOR INDUCING A SUBJECT TO FALL ASLEEP | 2011-02-24 |
20110046435 | SOUND ENRICHMENT FOR THE RELIEF OF TINNITUS IN DEPENDENCE OF SOUND ENVIRONMENT CLASSIFICATION - A sound enrichment system for provision of tinnitus relief, the sound enrichment system includes a noise generator, an environment classifier that is configured to determine a classification of an ambient sound environment of the sound enrichment system, a processing system for adjusting a noise signal based at least in part on the classification, wherein the noise signal is obtained using the noise generator, and an output transducer for conversion of the adjusted noise signal to an acoustic signal for presentation to a user. A method of providing a noise enriched sound signal for provision of relief of tinnitus includes obtaining a noise signal, adjusting the noise signal based at least in part on a sound environment classification, generating an acoustic noise signal from the adjusted noise signal, and presenting the acoustic noise signal to a tinnitus suffering person. | 2011-02-24 |
20110046436 | ANAL SLING SYSTEM AND METHOD TO TREAT FECAL INCONTINENCE - A method of implanting an anal sling in a patient having an anal sphincter with a defective portion, including: linking a first point on the anal sphincter and a second point on the anal sphincter, wherein the second point opposes the first point across the defective portion of the anal sphincter and tightening the anal sling across the defective portion of the anal sphincter. In a preferred embodiment, linking the first and second points on the anal sphincter includes passing a first end of the anal sling, coupled to a first-side needle tool, through the anal sphincter at the first point and passing a second end of the anal sling, coupled to a second-side needle, through the anal sphincter at the second point. | 2011-02-24 |
20110046437 | TISSUE RESTORATION DEVICES, SYSTEMS, AND METHODS - Tissue restoration devices, systems, and methods. In at least one embodiment, an implantable restraining device of the present disclosure comprises a first engaging component and a second engaging component, each component configured for laparoscopic insertion into a body cavity, a first swivel arm defining a first bend and a second swivel arm defining a second bend, the first swivel arm coupled to the first engaging component at a first pivot point and coupled to the second engaging component at a second pivot point, and the second swivel arm coupled to the first engaging component at a third pivot point and coupled to the second engaging component at a fourth pivot point, and a first interconnection arm and a second interconnection arm, the first interconnection arm connected to the first swivel arm relative to the first bend, and the second interconnection arm connected to the second swivel arm relative to the second bend. | 2011-02-24 |