Class / Patent application number | Description | Number of patent applications / Date published |
604089000 | Closure or barrier between compartments moved to permit mixing | 66 |
20080300536 | Drug Mixing and Delivery Device - A medicine mixer for applying drug comprises a menstruum vial ( | 12-04-2008 |
20090018496 | DUAL CHAMBER MIXING SYRINGE AND METHOD FOR USE - A mixing syringe and method for using the mixing syringe are provided. The mixing syringe comprises a housing having a first compartment for containing a first component, an outer plunger having a second compartment for containing a second component, and an inner plunger. Prior to use, a seal separates the first and second components. To prepare the mixture, the seal is pierced and the two components are mixed. The mixing syringe and its method of use are particularly suited to applications in which at least one of the mixture components is a relatively highly viscous material. | 01-15-2009 |
20090105637 | AN AUTOMATIC SYRINGE - A liquid-powder drug prompt-mixing type automatic syringe includes an injecting assembly, a drug-mixing assembly and a shooting device. The injecting assembly includes an injecting outer sleeve, in which the mouth of a blocking ampoule is slidably socketed, a needle is coaxially connected to the blocking ampoule by a hub; the drug-mixing assembly includes a drug-mixing outer sleeve, in which a precharging pressure menstruum bottle by a drug-mixing needle bracket; the shooting device includes a shooting outer sleeve and a spring pushing rod mechanism slidably socketed in the shooting outer sleeve a movable joining mechanism allows the injecting assembly to alternatively connect the drug-mixing assembly and the shooting device respectively. A liquid drug automatic syringe includes said injecting assembly and the shooting device. | 04-23-2009 |
20100010436 | Double burette syringe - The present invention discloses a device, which comprises a double burette syringe, a stopper, a slidable plate for mixing, and a plurality of mixing bars easily detachable from the mixing plate. This invention relates to devices for storing, delivering, and mixing of a two component double burette syringe. | 01-14-2010 |
20100042044 | Systems and Methods for Mixing Fluids - Improvements are provided for a syringe-to-syringe mixing system to improve the mixing characteristics of the system. In one embodiment, a mixing apparatus includes opposite fittings for mounting to a pair of syringes. The mixing apparatus defines a fluid passageway therethrough and includes a flow modifying element disposed within the passageway. The flow modifying element is configured to increase the flow velocity, disrupt the fluid flow or introduce turbulence into the fluid flow between the two syringes. In another embodiment, a nozzle element is disposed within the tip of the syringe, the element configured to increase the fluid flow therethrough. The nozzle element can be a nozzle insert removably mounted within the tip, or an integrally formed nozzle within the tip. | 02-18-2010 |
20100168664 | FLUID CONTROL DEVICE WITH MANUALLY DEPRESSED ACTUATOR - Fluid control device ( | 07-01-2010 |
20100198148 | LIQUID DRUG DELIVERY DEVICES FOR USE WITH SYRINGES WITH WIDENED DISTAL TIPS - Liquid drug delivery device includes a housing with a syringe port for sealingly receiving a syringe having a syringe tip ending at a widened distal tip, a vial adapter port with a vial adapter for snap fit receiving a vial, and a drug administration port for administering a liquid drug. The vial adapter is intended to be rotationally detached after a mixing procedure for discarding together with a spent vial. The syringe port additionally includes a single use locking mechanism for securing the syringe to preclude inadvertent syringe detachment under normal use including agitation for reconstitution purposes. The drug administration port has a distal tip preferably similar to a syringe's widened distal tip for the same purpose of preventing conventional needles with a female Luer connector being slidingly mounted thereon. | 08-05-2010 |
20100228190 | SEAL STRUCTURES FOR WET/DRY AUTOMATIC INJECTORS - An automatic medicament injector has a first compartment for a first medicament component and a second compartment for a second medicament component. The two compartments are separated by a seal structure that converts from a sealing condition to a mixing condition when the device is activated. The seal structure has a plug that opens a flow path through the seal structure to allow the second medicament component to mix with the first medicament component in the first compartment when the seal structure is in the mixing condition. | 09-09-2010 |
20100262074 | DUAL-CHAMBER CARPULE - The invention relates to a dual-chamber carpule having ( | 10-14-2010 |
20100274185 | AUTOMATIC INJECTION SYRINGE ASSEMBLY - An apparatus for actuating a syringe. The syringe includes a barrel, a plunger and a needle. A needle shield is near the front of the barrel and is movable from a first position enclosing the needle and a retracted position wherein the needle is exposed. A spring abuts the plunger. A cap has an interior wall for engaging the spring and releasably engages the plunger. The spring is compressed between the plunger and the interior wall when the cap releasably engages the plunger. A resilient member releasably secures the cap in releasable engagement with the plunger and is movable from a first position to a compressed position when the needle shield is moved from its first position to its retracted position. The cap disengages the plunger when the resilient member is moved to the compressed position wherein the spring expands to provide a medicament delivery pressure to the plunger. | 10-28-2010 |
20100274186 | DUAL-CHAMBER CARPULE WITH ATTACHMENT - The invention relates to a dual-chamber carpule comprising a cylinder ( | 10-28-2010 |
20100286605 | VALVE FOR MIXING OF SUBSTANCES - A valve is provided herein for permitting mixing of at least two components, the valve including a body configured for slidable liquid tight engagement with an injector or drug cartridge barrel. The body includes a proximal end, a distal end, and a channel extending therebetween, the channel having a proximal portion and a distal portion. A poppet is sealingly and slidably disposed in the channel to selectively move between first and second positions. The poppet includes a proximal end, a distal end, and a fluid channel, the fluid channel being defined in the poppet and extending from an outlet opening located distally of the distal end of the body. With the poppet being in the first position, the poppet defines a liquid tight seal in the channel such that liquid flow through the channel is prevented. With the poppet being in the second position, the fluid channel is in communication with the proximal portion of the channel so as to define a liquid flow path from the proximal portion of the channel to the outlet opening. Advantageously, with the subject invention, a valve is provided which permits controlled separation and mixing of substances in a standard injector or drug cartridge barrel, without any modification required thereto. | 11-11-2010 |
20100324480 | AUTOMATIC INJECTION SYRINGE ASSEMBLY - An apparatus for applying medicament delivery pressure to a plunger pad of a plunger of a syringe includes a spring having a first end and a second end, wherein the spring first end is operable to abut the plunger pad. The assembly also includes a shell including an interior and a first step therein. A cap is disposed within the shell interior. The cap includes a surface for engaging the spring second end. The cap is movable from a first position, wherein the shell first step retains the cap in releasable engagement with the plunger such that the spring is compressed between the cap surface and plunger pad, and a second position, wherein the cap disengages the shell first step such that the cap disengages the plunger such that the spring expands to move the barrel and needle forward as well as deliver medicament delivery pressure to the plunger pad. | 12-23-2010 |
20110201999 | NEEDLE MOUNTING FEATURE FOR ENSURING PROPER RECONSTITUTION SEQUENCE - A medical injector is provided herein having a body and a needle mounting surface movable relative to the body, the needle mounting surface having features for mounting a needle thereto. In an initial state, the needle mounting surface is disposed within the body with no needle mounted thereto. With relative movement between the body and the needle mounting surface, the needle mounting surface is urged out of the body. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered. | 08-18-2011 |
20110251553 | Medicament Delivery Device with Mixing Mechanism - A medicament delivery device comprising a housing ( | 10-13-2011 |
20110270167 | Injector having a displaceable stopper part - A disposable injector ( | 11-03-2011 |
20120035538 | Medicament Delivery Device - The present invention relates to a medicament delivery device comprising a generally elongated housing comprising a proximal part ( | 02-09-2012 |
20120041366 | MEDICAL INJECTOR WITH DOSE KNOB ACTIVATION FOR AUTOMATED RECONSTITUTION - A medical injector is provided herein having a body and a reservoir disposed in the body, the reservoir including at least first and second mixable components. At least one stopper is associated with the reservoir where distal advancement of the stopper over a predetermined distance causes mixing of the mixable components. A plunger is disposed in the body, along with a knob stem and a knob fixed to the knob stem so as to be rotatable therewith. A sleeve is telescopingly disposed over the knob stem, wherein the knob stem and the sleeve have cooperating elements formed thereon which selectively permit rotation of the knob stem to be transmitted to the sleeve so that the knob stem and the sleeve may rotate together. A spring is also provided for urging the sleeve distally. A releasable retainer releasably retains the sleeve against force of the spring. Rotation of the knob releases the sleeve and allows the spring to displace the sleeve distally. Distal movement of the sleeve causes distal movement of the plunger which causes distal movement of the stopper thus causing mixing of the mixable components. Advantageously, with the subject invention, a medical injector may be provided where autoreconstitution can be achieved by the turning of a knob. | 02-16-2012 |
20120041367 | MEDICAL INJECTOR WITH POST-AUTORECONSTITUTION DOSE SETTING AND AUTOPLUNGER DRIVE - A medical injector is provided herein having a body; a reservoir containing first and second mixable components, a stopper associated with the reservoir, a predetermined extent of advancement of the stopper causing mixing of the first and second mixable components; a displaceable plunger disposed in the body; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance from the first state to the second state. The plunger engages the stopper during the advancement from the first state to the second state so that the stopper traverses at least the predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for autoreconstitution with subsequent dose setting and autoplunger activation, the autoreconstitution and the autoplunger activations being activated by separate triggers. | 02-16-2012 |
20120078171 | DUAL-CHAMBER CARPULE WITH ATTACHMENT - The invention relates to a dual-chamber carpule comprising a cylinder comprising a bypass, a central plug and an end plug, and an attachment; the invention further relates to a method for producing and filling said dual-chamber carpule. | 03-29-2012 |
20120095394 | DUAL CHAMBER COMBINED CONTAINER-SYRINGE - A dual chamber combined container-syringe includes: an outer casing having a bypass portion; a hub lure lock; a front stopper; a middle stopper that seals a pharmaceutical preparation together with the front stopper; an end stopper that seals a liquid medicine together with the middle stopper; a finger grip; and a plunger rod that is connected to the end stopper from the rear end side, wherein a female screw portion twisted around an axis is formed on an inner peripheral surface of the finger grip, and a first male screw portion, a tip of which comes into contact with a rear end of the female screw portion and can be screwed into the female portion, and a first guide plate are formed on an outer peripheral surface of the plunger rod when a part of the middle stopper enters the bypass portion. | 04-19-2012 |
20120136298 | MIXING DEVICE WITH PISTON COUPLING ARRANGEMENT | 05-31-2012 |
20120203167 | USE OF AUTOLOGOUS SEDIMENT FROM FLUID ASPIRATES AS VEHICLES FOR DRUG DELIVERY - A filtration syringe having at least a first and second chamber separated by a fluid permeable membrane, which may be selectively permeable to solids of a certain size, allows aspirated particle-filled fluid to be filtered within the syringe. A centrifuge tube apparatus is also provided for centrifuging a sample collected in a syringe, the apparatus comprising: a syringe comprising at one end a narrowed outlet and means for connection to a needle and at the opposing end a partially inserted syringe plunger; and a syringe holder having an interior for accepting the syringe, wherein the interior comprises at least one ledge for resting the syringe in an inverted position within the holder to prevent further insertion of the plunger during centrifugation, further wherein the syringe holder is sized for insertion in a centrifuge rotor. | 08-09-2012 |
20120220930 | Seal Structures For Wet/Dry Automatic Injectors - An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly. | 08-30-2012 |
20120245516 | ADMINISTERING APPARATUS WITH FUNCTIONAL DRIVE ELEMENT - An apparatus for administering a fluid product, including a housing, a product member for accomodating the fluid product and/or a reservoir for the fluid product, which product member can be moved relative to the housing from a start position to an inserted position along a longitudinal axis of the housing, a drive member in the housing and movable relative to the product member for emptying the fluid product from the product member and/or the reservoir, wherein the drive member has at least one holding element which holds the drive member in the start position of the product member and wherein, by the movement of the product member, the holding element is moved from the holding position to a released position in which the drive member is movable relative to the housing. | 09-27-2012 |
20120253274 | Medicament Delivery Device - The present invention relates to a medicament delivery device comprising a distal housing part ( | 10-04-2012 |
20120310156 | Medicament Delivery Device - Injection device for manual penetration and injection comprising a distal housing part ( | 12-06-2012 |
20120310157 | AUTOMATIC ADMINISTRATION INSTRUMENT FOR MEDICAL USE - After pressing a part of the exterior of a body of an administration instrument against a body region of a patient to which a drug solution is to be administered, an injection needle that is housed in the instrument body is automatically protruded from the body to insert the needle into the body region, and further, the injection needle being inserted into the body region is automatically housed in the instrument body to remove the needle from the body region. Thereby, the pain of the patient during needle insertion and needle removal is reduced, and administration at a constant speed is possible during injection of the drug solution. Furthermore, even when two kinds of drug solutions or a dissolving and mixing type drug solution are/is used, mixing can be easily and reliably carried out. | 12-06-2012 |
20120323173 | MEDICAL SYRINGE FILLING AND VALVING - Apparatus and methods for providing a field environment filled proximal chamber of a multi-chamber syringe and for filling a prime-free syringe are disclosed. In addition, methods for resetting valves of a multi-chamber syringe without special tools or insertion of foreign objects into the syringe are disclosed. A valve for interfacing with syringes telescopically inserted into a larger syringe and which are generally used as proximal chambers in multi-chamber syringes used in mixing and serial delivery applications is disclosed. Four embodiments of novel resettable valves are disclosed. Also, a syringe assembly for delivering a saline-dose-saline medication sequence is disclosed. | 12-20-2012 |
20130090596 | PRE-FILLED SYRINGE - In a pre-filled syringe having an intermediate gasket, a liquid drug is enclosed in the second chamber located on the base end side with respect to the intermediate gasket while a powdered drug is enclosed in the first chamber located on the front end side with respect to the intermediate gasket. The intermediate gasket has at least two layers including a front end layer corresponding to a wall of the first chamber and a base end layer corresponding to a wall of the second chamber, and also has a low water-absorptive layer in the layer on the base end side with respect to the front end layer. The base end layer is formed of a material having low water-absorptivity and not lowering a pH of the liquid drug. | 04-11-2013 |
20130096495 | Medicament Delivery Device - A medicament delivery device includes a housing with a circle-segment-shaped compartment for a drive unit that moves at least one stopper in a medicament container and that includes a support wheel and central hub on which first and second parallel disks are fixedly attached and interconnected by an abutment cross-wall; spherical members between the abutment wall and adjacent the stopper; a clock spring within the hub with an outer end connected to the hub and an inner end connected to a one-direction-rotatable tubular hub coaxially arranged around a shaft fixedly attached to a housing part; and an activation member connected to the first disk by a hold-and-release mechanism. When the activation member is not depressed, the wheel and spring are held in a tensioned static state, and when the activation member is depressed, the spring and wheel are released and the spherical members are forced against the stopper. | 04-18-2013 |
20130131590 | Injection Device - Injection device comprising a tubular elongated main body, a needle shield slidably arranged in said main body, a needle shield link slidably connected to said needle shield, a enclosure containing medicament arranged in said main body, a needle connected to said enclosure, a plunger operatively arranged to said enclosure for ejecting said medicament through said needle and arranged on its upper part with a number of outwardly extending stop members, spring means arranged to said plunger for operating said plunger, a dose activating means, a needle shield spring surrounding the needle shield link. The injection device is capable of setting and delivering a certain preset dose. | 05-23-2013 |
20130226080 | MEDICATED MODULE FOR A DRUG DELIVERY DEVICE - A method and system for dispensing a non-user settable dose of one medicament and a user-settable dose of a primary medicament. The system may include a medicated module attachable to a drug delivery device, the drug delivery device having a drug reservoir holding a first medicament. The medicated module includes a first needle, a second needle, a collapsible feature holding a second medicament, a biasing feature operably connected to the collapsible feature, and a valve system having a closed position and an open position. During dispense, the valve system transitions from the closed position to the open position, and the biasing feature compresses the collapsible feature to force the second medicament to flow from the collapsible feature to the second needle. | 08-29-2013 |
20130226081 | Medicated Module for Administering Fixed Dose - A medicated module attachable to a drug delivery device. The medicated module comprises a housing configured for attachment to a drug delivery device. The drug delivery device comprises a first medicament. A collapsible reservoir is contained within the housing. A pre-determined volume of a second medicament is contained within the reservoir. A needle arrangement is configured within the housing and the needle arrangement is arranged in fluid communication with the collapsible reservoir. A needle shroud may be configured, such that, during an injection step, the shroud acts on the reservoir to inject the second medicament. | 08-29-2013 |
20130237905 | Medicament Delivery Device - The invention relates to a medicament delivery device comprising a housing arranged to receive a medicament container ( | 09-12-2013 |
20130345626 | Mixing/Administration Syringe Devices, Protective Packaging and Methods of Protecting Syringe Handlers - Medicant mixing/administration systems are provided that can include: a medicant vial; a syringe assembly comprising a barrel and a piston; a protective material supporting the syringe assembly and medicant vial; and a member within the system, the member separating the piston of the syringe assembly from the medicant vial. Systems are provided that can include: a syringe assembly comprising a barrel and a piston; having a forward end and an opposing back end; a protective material supporting the syringe assembly; and a needle housing coupled to the protective material. Medicant mixing/administration methods are also provided that can include, within a package, sufficiently clearing a restraining member from between a medicant vial and syringe plunger to pierce the medicant vial with a piercing structure coupled to the syringe plunger, the piercing providing medicant from the vial to the syringe assembly. Additional methods can include, upon opening a package containing a syringe assembly, extending a needle housing from the package. | 12-26-2013 |
20140058320 | Piston Rod Drive System for a Drug Delivery Device - A piston rod drive system is provided comprising a main body adapted for coupling with a reservoir, a user operable activation element operatively coupled with the main body and configured to move axially and rotationally relative to the main body between a first position and a second position, and a piston rod element operatively coupled with the activation element and the main body and configured to move axially and non-rotationally relative to the main body in response to the activation element being moved between the first position and the second position. | 02-27-2014 |
20140066846 | BENEFICIAL AGENT DISPENSER - A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port. | 03-06-2014 |
20140155820 | Medicament Delivery Device - A medicament delivery device includes a housing having a proximal housing part and a distal housing part movable relative each other, a drive force mechanism accommodated in the distal housing part, a container filled with medicament arranged within the proximal housing part, a holding member for holding the drive force mechanism in a loaded state, and an actuation member arranged to interact with the holding member for releasing the drive force mechanism from its loaded state. The holding member is arranged to be moved from a disengaged position, in which the holding member is disengaged from the actuation member, to an engaged position, in which the holding member is engaged to the actuation member by moving the housing parts in relation to each other. | 06-05-2014 |
20140276385 | PORTABLE DRUG MIXING AND DELIVERY SYSTEM AND METHOD - A portable auto-injector is capable of moving from a compact state where the auto-injector is in a shape easier to transport than in an activation state wherein the auto-injector has been extended. A safety limits movement of the needle assembly and prevents premature needle sticks. The drug is stored in one or more dry and wet medicament states until need. | 09-18-2014 |
20140309586 | INJECTION DEVICE FOR SOFT-TISSUE AUGMENTATION FILLERS, BIOACTIVE AGENTS AND OTHER BIOCOMPATIBLE MATERIALS IN LIQUID OR GEL FORM - Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof. | 10-16-2014 |
20140316334 | Device for Medicament Delivery with Syringe-like Usability Having a Restraining Mechanism - Device for medicament delivery with syringe-like usability having a restraining mechanism A device for medicament delivery with syringe-like usability comprising at least one grip, at least one medicament container holder, and at least one plunger rod being substantially rotationally fixed relatively to the grip. The medicament container holder ( | 10-23-2014 |
20140350460 | Cartridge Hub with Active Valve - The invention is related to a dispense interface for a drug delivery device for delivering at least two drug agents, wherein the dispense interface is configured to be coupled to a cartridge holder of the drug delivery device, wherein the cartridge holder is configured to hold at least two cartridges, wherein the dispense interface comprises at least two inlet channels, each comprising a fluid inlet opening, wherein each fluid inlet opening is configured to receive fluid from a respective cartridge of the at least two cartridges when the dispense interface is axially coupled to the cartridge holder, an outlet channel comprising a fluid outlet opening, a valve structure configured to be selectively moved into any one of a plurality of positions, wherein in at least one position the valve structure selectively permits or prevents fluid flow from any of the at least two inlet channels to the outlet channel. The invention is further related to a drug delivery device for delivering at least two drug agents comprising a dispense interface of the aforementioned kind | 11-27-2014 |
20150018761 | Seal Structures for Wet/Dry Automatic Injectors - An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly. | 01-15-2015 |
20160106921 | WEARABLE AUTOMATIC INJECTION SYSTEM AND APPARATUS - A wearable automatic injection device is provided for administering a final medicament to a patient. The wearable automatic injection device comprises a housing, an injection assembly for injecting the patient with the final medicament, a container holding a bulk intermediate medicament and a diluent to be mixed to form the medicament, and a mixing mechanism for mixing the bulk intermediate medicament and the diluent in the container to form the final medicament prior. A system for administering a final medicament to a patient is also provided. The system comprises a container, a mixing mechanism for mixing a bulk intermediate medicament and a diluent in the container to form the final medicament, and a wearable automatic injection device configured to receive the container. | 04-21-2016 |
20160184519 | COVER BIASING MEANS FOR AN APPARATUS - The invention relates to an Apparatus, especially a delivery device, comprising a housing ( | 06-30-2016 |
604090000 | Closure moved, expanded, or flexed by force transmitted by liquid | 6 |
20090099512 | SYRINGES WITH A REDUCED SUSCEPTIBILITY TO FREEZE-THAW VOID FORMATION AND METHODS OF MANUFACTURING SUCH SYRINGES - Syringes for holding fluids susceptible to void formation when the syringe and fluid are frozen and thawed before use. The interior surface of the syringe barrel is modified by exposure to a plasma such that the incidence of void formation in the fluid is prevented or, at the least, significantly reduced in comparison with conventional syringes. | 04-16-2009 |
20110319814 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 12-29-2011 |
20140163465 | RECONSTITUTION DEVICES - A one-part reconstitution device is described, for temporarily separating two substances into two compartments within a cartridge or syringe and allowing for mixture of the two substances within the cartridge or syringe. In various embodiments, the one-part reconstitution device may include an outer, contact portion configured to contact an inner surface of the cartridge or syringe, and an inner, deflection portion positioned within the contact portion. The deflection portion may be movable from a locked position, in which the deflection portion causes the contact portion to exert a first radial force against the inner surface, to an unlocked position, in which the deflection portion causes the contact portion to exert a second radial force against the inner surface. The second radial force may be less than the first radial force, and the contact portion and the deflection portion may comprise one part. | 06-12-2014 |
20150094652 | NEEDLE MOUNTING FEATURE FOR ENSURING PROPER RECONSTITUTION SEQUENCE - In one aspect, a medical injector is provided herein having a body and an overcap releasably attached to the body configured to prevent mounting of a needle prior to mixing of components within the body. In a further aspect, a slidable collet may be provided useable to urge resilient members from an outward disrupted state inwardly to collectively define a needle mount. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered. | 04-02-2015 |
20150141913 | RECONSTITUTION DEVICE - An apparatus comprises a plunger able to fit in a cartridge or syringe. The plunger includes an outer portion and a deflection portion. The outer portion is able to engage the body of the cartridge or syringe. The outer portion is operable to apply a first radial force to the cartridge or syringe. The deflection portion is positioned within the outer portion and is movable between a locked position and an unlocked position. The deflection portion in the unlocked position causes the outer portion to apply a second radial force to the cartridge or syringe. | 05-21-2015 |
20150314080 | Needle Mounting Feature for Ensuring Proper Reconstitution Sequence - In one aspect, a medical injector is provided herein having a body and an overcap releasably attached to the body configured to prevent mounting of a needle prior to mixing of components within the body. In a further aspect, a slidable collet may be provided useable to urge resilient members from an outward disrupted state inwardly to collectively define a needle mount. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered. | 11-05-2015 |
604091000 | Closure moved by relative movement between closure and separate protruding member | 14 |
20090112157 | MIXING DEVICE INCLUDING A PLUNGING MIXING MEMBER FOR USE WITH A SYRINGE - Mixing devices used with a syringe or syringe system and related systems for mixing dissimilar components contained therein. The devices and systems include a hollow elongate handle having a proximal end, a distal delivery end, and a delivery passageway therethrough. A mixing member is disposed at or near the proximal end of the hollow elongate handle, which mixing member and a portion of the handle are axially slidable within a syringe barrel during use. The user may push and pull the distal end of the handle, causing corresponding axial movement of the mixing member within the syringe barrel. The devices and systems may be used to homogenously mix difficult to mix two part compositions, as well as single part compositions which include components that may tend to separate over time (e.g., a fluoride varnish composition). | 04-30-2009 |
20120184900 | INJECTION DEVICE - A pen injection device designed for use with dual or multi-chamber cartridges | 07-19-2012 |
20140371670 | Medicament Delivery Device - A medicament delivery device for a reconstituted medicament, comprising a proximal housing part ( | 12-18-2014 |
20150025454 | SYRINGES FOR PREFILLED AND FILL-AT-USE MIXING AND DRUG DELIVERY - Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject. | 01-22-2015 |
20150025455 | SYRINGES FOR REPETITIVE MIXING AND DELIVERY OF INJECTABLES - Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject. The repetitive mixing of substances contained in a distal and proximal chamber is also provided, where the plunger rod is configured to releasably engage a locking mechanism to actuate the valve, and can axially displace the distal seal assembly while the fluid passage is open. | 01-22-2015 |
20150025456 | SYRINGES FOR SEQUENTIAL DELIVERY OF INJECTABLES - Sequential delivery syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject. The sequential delivery of substances contained in a distal and proximal chamber is also provided, where a second substance from the distal chamber is delivered followed by the delivery of a first substance from the distal chamber after the first substance from the proximal chamber is transferred into the distal chamber involving the actuation of the valve mechanism. | 01-22-2015 |
20150057608 | Delivery Device and Components Thereof - Delivery devices and components thereof are disclosed. In an embodiment, a delivery device may include a barrel holding a liquid for delivery. The delivery device may also include a finger flange assembly coupled to the barrel. The finger flange assembly may include a first flange and a second flange each extending laterally from opposite sides of the finger flange assembly, wherein the first flange and the second flange each curve toward the barrel. The delivery device may also include a plunger coupled to the barrel and passing through the finger flange assembly. The plunger may also include a disc-shaped head. | 02-26-2015 |
20150297458 | RAPID RECONSTITUTION PACKAGES FOR MIXING AND DELIVERY OF DRUGS - Rapid reconstitution package. The package includes a substantially cylindrical structure including a diluent chamber and a drug chamber communicating through a valve. The cylindrical structure is configured to retract under an axial force causing the valve to open to allow the diluent to flow through the valve into the drug chamber for mixing and reconstitution of the drug. The drug chamber shape is tuned to enhance mixing. In another aspect, the invention is a method for designing a rapid reconstitution package using computational fluid dynamics techniques. | 10-22-2015 |
20150320935 | COMBINATION PLUNGER DEVICE FOR A DUAL CHAMBER MIXING SYRINGE - A combination plunger, a mixing device and a mixing syringe including the same are provided. The mixing syringe includes concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. The combination plunger includes a mixing plunger and a delivery plunger and a biasing means. The mixing plunger is slidably located in the outer chamber and translated by coordinated depression of the delivery plunger to transfer a first substance from the outer chamber to mix with a second substance in the inner chamber. After the mixing stage is complete, the delivery plunger is disengaged from the mixing plunger and permitted, such as by rotation, to be further depressed in the axial direction to deliver fluid contents of the mixing syringe to a recipient. The mixing syringe needle is then retracted as result of engagement by the delivery plunger and activation of the biasing means. | 11-12-2015 |
20150367073 | Portable Drug Mixing and Delivery Device and Associated Methods - A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a valve between a first and second chamber that are slidably movable relative to each other and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete. | 12-24-2015 |
20160058947 | SYRINGE FOR DISPENSING A MEDICAMENT - A syringe for dispensing a medicament comprises a cartridge, a plug and an activator member. The syringe comprises a main chamber containing a first liquid and an auxiliary chamber containing a second liquid. To activate the syringe and merging the first and second liquid to form the medicament the auxiliary chamber and the main chamber are connectable for fluid communication with each other. A movement of the activator member and/or the plug causes the second liquid to be transferred from the auxiliary chamber into the main chamber. The syringe helps facilitating the preparation of a medicament that has to be mixed from different liquids shortly prior to use. | 03-03-2016 |
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20170232187 | Unified Drug Mixer And Dispenser | 08-17-2017 |
20190143046 | TRIPLE CHAMBER WITH PREFILLED INJECTION DEVICE | 05-16-2019 |