Entries |
Document | Title | Date |
20080200817 | Electronic Polarimetric Imaging System for a Colposcopy Device and an Adapter Housing - The invention relates to an electronic polarimetric imaging system use in a colposcopy device for in vivo monitoring a cervix, which is provided with a light source for illuminating the observable cervix and at least visual means for monitoring said cervix, wherein the illumination optical path directed to the cervix and the image optical path coming back from the cervix are separated from each other on at least a portion of the paths thereof. The inventive system comprises a polarimetric adapter housing which is removable in the separated portion of the illumination and image optical paths and comprises a polarization state generator (PSG) positioned on the illumination optical path and a polarization analyser (PSA) positioned on the image optical path, wherein said polarization state generator (PSG) and polarization analyser (PSA) are designed in such a way that they are controllable. Said invention makes it possible to obtain several polarimetric characterisation levels. The adapter housing is also disclosed. | 08-21-2008 |
20080200818 | Surface measurement apparatus and method using parallax views - The invention provides for surface mapping of in-vivo imaging subjects using a single camera having a lens which is not telecentric in object space, and a moveable stage on which a subject animal for in-vivo imaging is placed. Images are taken and the stage is moved by known amounts, and the height of individual features on the subject is determined through analysis of how much the feature shifts in the image, given the known stage displacement and lens placement. A mesh or other surface can be constructed from individual features, to provide a map of the subject. Alternatively, two cameras are used in a calibrated stereo viewing arrangement. Resolution of 0.5 mm or better can be attained for mice and similarly sized subjects. | 08-21-2008 |
20080221456 | Optical Sensor and a Method of Its Use - The invention provides a device | 09-11-2008 |
20080255457 | Method For Evaluating Relative Oxygen Saturation in Body Tissues - A new method was discovered to analyze continuous spectral curves to determine relative hemoglobin oxygen saturation, using spectral curves collected from a continuous range of wavelengths from about 530 nm to about 584 nm, including spectra from transmitted or reflected light. Using isosbestic points and curve areas, a relative saturation index was calculated. With this method, noninvasive, in vivo measurement of relative oxygen saturation was made using light reflected from blood vessels in the eye and to map and measure relative changes in hemoglobin oxygen saturation in primate retinal vessels and optic nerve head in response to controlled changes in inspired oxygen and intraocular pressure (IOP). This method could also measure oxygen saturation from other blood vessels that reflect light sufficient to give a clear spectra from the blood hemoglobin. Changes in blood oxygen saturation can be monitored with this method for early detection of disease. | 10-16-2008 |
20080255458 | SYSTEM AND METHOD USING FLUORESCENCE TO EXAMINE WITHIN A PATIENT'S ANATOMY - A system for examining an area of a patient's anatomy that comprises a probe capable of fluorescing, and a scanning beam assembly that scans the probe with a beam of excitation radiation and detects the probe's fluorescence. The scanning beam assembly including a radiation source capable of emitting one or more wavelengths of radiation that are capable of exciting the probe and causing the probe to fluoresce, a scanning device that directs the radiation onto a field-of-view to create a scan of the field-of-view, a detector to detect radiation returned from the field-of-view, and a controller to convert the detected radiation into a displayable fluorescence image. | 10-16-2008 |
20080255459 | SENTINEL NODE IDENTIFICATION USING FLUORESCENT NANOPARTICLES - Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect. | 10-16-2008 |
20080255460 | NANOPARTICLE TISSUE BASED IDENTIFICATION AND ILLUMINATION - Various compositions, methods, and devices are provided that use fluorescent nanoparticles to function as markers, indicators, and/or light sources. In an exemplary embodiment, the fluorescent nanoparticles are biocompatible, and more preferably they can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one aspect, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. | 10-16-2008 |
20080255461 | Real-time optical monitoring system and method for thermal therapy treatment - Multiple site information of light intensity is obtained by application of a multiple-fibre probe in a real-time optical monitoring system. The multiple-fibre probe includes a plurality of optical fibres distributed along the length of the probe. Each optical fibre may be is switchable between the mode for transmitting optical signal into the malignant tissue and the mode for collecting the optical signal from the same tissue. Thus the numbers of the probes can be minimized for collecting multiple site light information and the irritation to the tissue is reduced. A method of using such a probe to determine coagulated boundary in thermal or other treatment is also described. | 10-16-2008 |
20080255462 | LIGHT STICK - Described herein is a device used to perform medical examinations. The device includes at least one sidewall and at least one end, wherein the sidewall at least partially defines both a chemical housing and a handle portion. The chemical housing preferably includes a light source disposed therein. A reflective layer may be applied to at least a portion of the sidewall defining the chemical housing. | 10-16-2008 |
20080262359 | SYSTEM AND METHOD PROVIDING INTRACORONARY LASER SPECKLE IMAGING FOR THE DETECTION OF VULNERABLE PLAQUE - Apparatus and method according to an exemplary embodiment of the present invention can be provided for analyzing tissue. For example, the apparatus can include at least one first arrangement configured to illuminate at least one anatomical structure with at least one of at least one electro-magnetic radiation. The apparatus can also include at least one second arrangement that may include at least two wave-guiding arrangements associated with one another that are configured to receive a further electro-magnetic radiation reflected from the tissue and transmit at least one speckle pattern associated with the further electro-magnetic radiation. The wave-guiding arrangements may be structured so as to reduce crosstalk therebetween. | 10-23-2008 |
20080269617 | Absorption and Scattering Map Reconstruction For Optical Fluorescence Tomography - Optical fluorescence tomography is a highly sensitive method to image contrast agents in the body. However, current reconstruction methods suffer from a high complexity or even instability. According to an exemplary embodiment of the present invention, a method for absorption/scattering map reconstruction for optical fluorescence tomography may be provided, which uses a spectral model. This may provide for a subsequent fluorescence reconstruction with improved image quality. | 10-30-2008 |
20080281207 | Image acquisition through filtering in multiple endoscope systems - A method of one aspect may include illuminating a surface with a broad bandwidth light from a first endoscope. The broad bandwidth light typically has a bandwidth of at least 200 nanometers (nm). A beam that includes at least one narrow bandwidth light may be scanned over the surface with a second, scanning beam endoscope. The narrow bandwidth light typically has a bandwidth of less than 3 nm. During the scanning, light that has been backscattered from the surface may be collected with the scanning beam endoscope. The collected backscattered light may be filtered with at least one narrow bandwidth band-pass optical filter. A band-pass bandwidth of the filter may be no more than 15 nm and may at least partially overlap the bandwidth of the narrow bandwidth light. The filtered backscattered light may be detected with a photodetector. | 11-13-2008 |
20080287807 | GLOBAL MOTION INVARIANT SIGNATURES FOR FAST AND ACCURATE MOTION TRACKING IN A DIGITAL IMAGE-BASED ELASTO-TOMOGRAPHY SYSTEM - A method for converting digital images of an actuated breast into an accurate description of breast surface motion from a digital image-based elasto-tomography system comprises the steps of artificially placing a high density of fiducial markers on the breast surface, whereby the fiducial markers have different qualities and are placed in different proportions according to their quality; utilizing motion invariant properties of the fiducial markers to form a global motion invariant signature; tracking the markers on the actuated breast surface from image to image in each digital camera using the global motion invariant signature; and using the cameras calibration to measure the breast surface motion. | 11-20-2008 |
20080287808 | APPARATUS, PROBE AND METHOD FOR PROVIDING DEPTH ASSESSMENT IN AN ANATOMICAL STRUCTURE - Apparatus and method can be provided for obtaining information regarding at least one portion of an anatomical structure. For example, using at least one first arrangement, it is possible to forward at least one first electromagnetic radiation to the at least one portion. In addition, using at least one second arrangement, it is possible to detect at least one second electromagnetic radiation from the sample, the second electromagnetic radiation being related to the first electromagnetic radiation. The second arrangement can be used to obtain data associated with the second electromagnetic radiation at a plurality of integration times. Further, with at least one third arrangement, it is possible to determine at least one motion characteristic as a function of depth within the portion using the second electromagnetic radiation. The motion characteristic can be determined by obtaining data associated with the second electromagnetic radiation. The data can be speckle data detected by the second arrangement. In addition, using the third arrangement, it is possible to determine optical properties of the portion based on the data. Furthermore, with a fourth arrangement, it is possible to receive the first electromagnetic radiation and generate a plurality of third electromagnetic radiations to irradiate multiple points on the portion. The second arrangement can be used to detect the second electromagnetic radiation from the sample based on the third electromagnetic radiations, and the third arrangement can also be used to determine a plurality of motion characteristics as a function of depth for a plurality of location of the at least one portion as a function of the second electromagnetic radiation. | 11-20-2008 |
20080287809 | Biological information measuring apparatus and biological information measuring method - A biological information measuring apparatus measures information of a living body by irradiating the living body with light. The apparatus includes: a first light source irradiating the living body with light; a second light source irradiating the living body with light; and a light receiving section constituted by a plurality of light receiving elements that receives reflected light reflected by the living body or transmitting light transmitting through the living body, during light irradiation of the living body. In the biological information measuring apparatus, the first light source and the second light source are disposed so that a first distance between the light receiving section and the first light source is different from a second distance between the light receiving section and the second light source. | 11-20-2008 |
20080294056 | BISPECTRAL PEROPERATIVE OPTICAL PROBE - The general field of the invention is that of peroperative optical probes designed to assist surgeons in performing medical procedures. The optical probes of the fluorescence type according to the invention are designed to be used on living tissues where the diseased areas have been marked by a fluorescent marker. They have dual lighting. The first situated in the red or near-infrared spectrum is necessary for achieving the fluorescence of the marked areas and for obtaining an image exploitable by a camera. The second situated in the visible spectrum is necessary for illuminating the marked areas with visible light, thus making the surgeon's work easier. The visible lighting can be punctiform or can be provided by an image projector. In the latter case, the projected image illuminates only the diseased areas. | 11-27-2008 |
20080312539 | Methods of Using Optical Agents - In certain aspects, the invention relates to processes for using renally excretable optical agents to detect one or more tissues of the renal system of a surgical patient. In certain aspects, the invention relates to a kit including a biocompatible composition containing one or more optical agents and instructions for using the optical agent(s) in a process of the present invention. | 12-18-2008 |
20080319322 | Non-invasive in-vivo imaging of mechanoreceptors in skin using confocal microscopy - Meissner's Corpuscles (MCs) are touch-pressure sensation receptors in glabrous skin. They are imaged by reflectance confocal microscopy to provide a non-invasive, in vivo quantification of their density or size to allow screening for, diagnosis or monitoring of sensory neuropathy and other peripheral nervous system disorders related to diabetes, HIV, or other conditions. | 12-25-2008 |
20080319323 | Tear film measurement - The invention comprises a method for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking. Light is directed to the lipid layer of a patient's eye with an illuminator. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer. In order to facilitate ease of measurement, the patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the patient's eye. | 12-25-2008 |
20090005691 | METHODS AND SYSTEMS FOR BLOOD FLOW MEASUREMENT USING DOPPLER OPTICAL COHERENCE TOMOGRAPHY - This invention provides methods for non-invasive, real-time measuring and/or monitoring of local blood flow in a subject. Methods of the invention generally include the steps of obtaining Doppler shift images of at least two planes intersecting blood vessels at the scanned location; determining Doppler angles using the Doppler shift images; and then using the Doppler angles thus determined together with the Doppler shift signals to arrive at a measure of the volumetric blood flow. Also provided are systems and software for performing the methods. | 01-01-2009 |
20090012403 | METHOD FOR DETERMINATION OF BONE FRACTURE RISK USING RAMAN SPECTROSCOPY - A method is disclosed for analyzing keratinized tissue, particularly fingernails, of a subject to diagnose osteoporosis and bone fracture risk. A Raman spectrum of a sample of keratinized tissue is generated. Broad spectral background features of the spectrum are removed, preferably by using Fourier transform analysis. Peak heights of Raman features of interest, particularly the S—S bond of cystine, are measured. These peak height measurements are normalized using reference peak heights of Raman features that are invariant between normal and osteoporotic subjects, such as the CH | 01-08-2009 |
20090012404 | Electronically Scanned Optical Coherence Tomography With Frequency Modulated Signals - An improved Optical Coherence Domain Reflectometry (OCDR) system is provided. One embodiment of this OCDR system outputs a detector signal carrying image depth information on multiple modulation frequencies, where each modulation frequency corresponds to a different image depth. The image depth information from the detector signal may be resolved by tuning to the desired modulation frequency. Another system for imaging body tissue uses multiple frequency modulators such that the light beam does not travel from an optical fiber to free space. | 01-08-2009 |
20090018451 | Dynamic Sampling System and Method for In Vivo Fluorescent Molecular Imaging - A dynamic dada sampling system and method is disclosed for in vivo small animal fluorescence molecular imaging and dual-modality molecular imaging. The system comprises a computer, a rotation stage for animal suspension driven by a motor, and a fluorescence excitation-detection apparatus. The fluorescence excitation-detection apparatus comprises a fluorescence excitation module and a fluorescence detection module. The CCD device of the fluorescence detection module is connected to a computer through an interface controller. The motor is connected to a computer through RS232 interface. The process of dynamic data acquisition is as follows: a fluorescent probe is injected into a small animal in order to target specific cells or tissues; a small animal is vertically hung on a rotation stage after anesthesia; the fluorescence imaging detection module acquires the emitting light continuously. The present invention can provide 360 degree imaging quickly, efficiently, and non-invasively. | 01-15-2009 |
20090018452 | PROBE ADAPTED TO MEASURE BIOLOGICAL SIGNAL - A probe is adapted to emit light having at least one wavelength as irradiation light with respect to a measured portion on a biological body in order to measure a biological signal. A light emitting element is configured to emit the light having the at least one wavelength. A light guiding member is provided with: a first end face, being light-reflective and having a first part opposing the light emitting element and a second part surrounding the first part; a second end face, being light-reflective and intersecting the first end face; and a third end face, being light-permeable, opposing the first end face and intersecting the second end face. The light guiding member is configured such that at least part of the light emitted from the light emitting element is reflected by at least one of the first end face and the second end face, and emitted from the third end face as the irradiation light. A light receiving element is configured to receive light reflected by the measured portion. A section shape of the first end face in a direction along an optical axis of the light emitting element is such a shape that at least the second part is coincident with a circumference of an ellipse intersecting a minor axis of the ellipse, and the optical axis of the light emitting element is coincident with the minor axis of the ellipse. | 01-15-2009 |
20090024041 | Apparatus for measuring bio-information - Disclosed is an apparatus for measuring bio-information of a user. The apparatus includes an input device for receiving basic bio-information of the user, a first light source radiating a first light having a first wavelength on the surface of the skin, a second light source radiating a second light having a second wavelength on the surface of the skin, a third light source arranged so as to be placed in a more distant position from a photo detector than the first and the second light sources, said third light source radiating a third light having a third wavelength on the surface of the skin, the photo detector for detecting a first, second and third detection lights transmitted through the surface of the skin and converting said first, second and third detection light into electrical signals, said first, second and third detection light corresponding to said first, second and third wavelengths and a control unit for enabling the first, second and third light sources to be driven in a known order and for producing bio-information of the user on the basis of the inputted basic bio-information and intensities of the first, second and third detection lights. | 01-22-2009 |
20090036782 | SYSTEMS AND METHODS FOR PROVIDING BEAM SCAN PATTERNS FOR HIGH SPEED DOPPLER OPTICAL FREQUENCY DOMAIN IMAGING - An exemplary apparatus and/or an exemplary method can be provided using which, it is possible (e.g., with at least one first arrangement) to measure an amplitude and/or a phase of at least one electromagnetic radiation provided from a particular portion of a sample. Further, it is possible (e.g., using at least one second arrangement) to scan a location of the particular portion along a path from a first point of the sample to a second point of the sample. In addition, it is possible to control the scan (e.g., with the second arrangement) such that the scan may comprise at least one first segment having a positive velocity and at least one segment having a negative velocity. A first distance of the first segment and/or the second segment can be smaller than a second distance between the first and second points. | 02-05-2009 |
20090036783 | Biometric image pickup apparatus - A biometric image pickup apparatus includes: a light source section selectively switching between light of a first wavelength region with a high transmittance through a living organism and light of a second wavelength region with a lower transmittance through the living organism than light of the first wavelength region to apply the light of the first wavelength region and the light of the second wavelength region to the living organism; an image pickup lens section condensing light from the living organism; an image pickup device obtaining first image pickup data of the living organism on the basis of the light of the first wavelength region in light condensed by the image pickup lens, and obtaining second image pickup data on the basis of the light of the second wavelength region in the light condensed by the image pickup lens. | 02-05-2009 |
20090043210 | DATA DETECTION DEVICE AND DATA DETECTION METHOD - A data detection device ( | 02-12-2009 |
20090054786 | IMAGING SYSTEMS AND METHODS, PARTICULARLY FOR USE WITH MEDICAL INSTRUMENT USED IN OPEN SURGERY - An electronic assembly (and related methods of manufacture and use), comprising: a non-conducting substrate, which has front and back sides and comprises through-wires molded into the substrate so as to pass through the substrate from the front side to the back side; and an integrated circuit device, which is fixed to the front side of the substrate and electrically connected to the through wires at the front side of the substrate. In certain embodiments, the integrated circuit device may be an image sensor. In one possible embodiment, the assembly is used as a compact camera that is associated with a surgical instrument used in open surgery. | 02-26-2009 |
20090054787 | IMAGING SYSTEMS AND METHODS, PARTICULARLY FOR USE WITH MEDICAL INSTRUMENT USED IN OPEN SURGERY - Systems and methods for use in performing an open surgical procedure on a body of a patient using a working element of a surgical instrument that has a shaft connected proximally to the working element; and capturing an image of an area of the body using a camera that is connected to the shaft. | 02-26-2009 |
20090054788 | METHOD AND APPARATUS FOR DISPLAYING A FIELD OF A BRAIN OF A PATIENT AND NAVIGATION SYSTEM FOR BRAIN SURGERY - A method and an apparatus for displaying a part of a brain of a patient is described. Laser-Doppler-images are acquired before and after a stimulation. The laser-Doppler-images include information about a blood motion or about a perfusion at the acquired part. Then, the blood motion images acquired before and after the stimulation are compared to identify areas in the brain of the patient which are related to the stimulation. | 02-26-2009 |
20090054789 | Head-coupled holder for living body optical measurement - A head-coupled holder for living body optical measurement that securely brings a light irradiation module and a light detection module in close contact with a scalp, and gives the person to be examined no excessive pressure feeling. Each of the light irradiation module and the light detection module includes a contactor having a contact portion that comes in contact with a scalp of the person to be examined at a leading end thereof, and exposes a leading end of a light guide to the contact portion to form the light guide, and a package having a lower portion to which the contactor is attached. The contactor is fixed to the lower portion of the package through an elastic body, and the package is fixed to an inner upper wall of the insertion hole with a series structure of the elastic body and the viscoelastic body. | 02-26-2009 |
20090054790 | Method and Arrangement for Generating a Signal which Corresponds to the Degree of Opening of the Vocal Folds of the Larynx - The invention relates to a method for generating a signal which corresponds to the degree of opening of the vocal folds of the larynx, in which the vocal folds are illuminated by means of a light source and are optically observed by means of an endoscope and a signal which is modulated by the movement of the vocal folds, the vocal fold signal, is displayed and/or recorded, wherein the vocal folds are illuminated with light having a wavelength greater than 600 nm or with red light, and wherein the light which is modulated by the movement of the vocal folds, the vocal fold light, is received by a sensor and is detected in order to generate a vocal fold signal which can be visualised, and visible light which contains little infrared or red light is used at the same time to observe the vocal folds. | 02-26-2009 |
20090062658 | POSITION TRACKING AND CONTROL FOR A SCANNING ASSEMBLY - A scanned beam imaging system including a radiation source configured to provide a beam of radiation, a movable element configured to direct the beam of radiation onto a scanned area, and a collector configured to receive radiation returned from the scanned area. The imaging system further includes a housing that houses the movable element therein and a reference mark coupled to or received in the housing. The reference mark is positioned such that at least part of the radiation from the radiation source is directable at the reference mark. | 03-05-2009 |
20090062659 | MEDICAL DEVICE INCLUDING SCANNED BEAM UNIT WITH OPERATIONAL CONTROL FEATURES - A method of controlling a medical device is provided. The method includes generating a beam of radiation using a radiation source assembly. The beam of radiation is directed toward a distal end of the medical device using an optical fiber. The beam of radiation is directed onto an area of interest by scanning the reflector in a scanning pattern, the reflector receiving the beam of radiation from the optical fiber. Radiation is collected from the area of interest using a collector to generate a signal for use in producing a viewable image. A loss of scan condition of the reflector is detected automatically by a control system. | 03-05-2009 |
20090062660 | Examination and imaging of brain cognitive functions - A system and method for examining or imaging brain functions of a subject includes a light source and a light detector located on the exterior surface of the subject's head. The light source introduces transcranially optical radiation into the brain of a subject, and the light detector detects radiation that has migrated in a brain region from the light source to the detector. The system also provides brain stimulation and evaluates the detected radiation to determine a brain cognitive function of the subject. One embodiment of the system can detect a brain disorder. Another embodiment of the system can detect “deceit.” In addition to the optical module, the system may include other optional modules such as an EEG module, an MEG module, a thermography module, a respiratory module, a skin conductivity module, and a blood pressure module. | 03-05-2009 |
20090062661 | SENSOR FOR MEASURING LIVING BODY INFORMATION AND EARPHONE HAVING THE SAME - A sensor for measuring living body information includes a light guide member for guiding a first light; a light extracting member, disposed adjacent to the light guide member, for outputting the first light guided by the light guide member to an exterior of the light guide member through contact with the light guide member; and a light coupling member, disposed adjacent to the light guide member, for coupling a second light to the light guide member through contact with the light guide member. | 03-05-2009 |
20090069697 | ACTIVE MICRONEEDLES AND MICRONEEDLE ARRAYS - An active needle device for fluid injection or extraction includes at least one hollow elongated shaft defining at least one channel. The channel provides communication between at least one input port and at least one output port of the needle device. At least one active component such as a sensor or actuator is placed or integrated into the elongated shaft. The needle device can include a macroneedle, a microneedle, or an array of macroneedles or microneedles. The microneedles can be fabricated on a substrate which can remain attached to the microneedles or be subsequently removed. The active component can facilitate biochemical, optical, electrical, or physical measurements of a fluid injected or extracted by the needle device. | 03-12-2009 |
20090076396 | Optical wavelength range for high contrast imaging of cancer - An apparatus for imaging cancer in which cancer tissue is contrasted against adjacent healthy tissue. The apparatus includes illumination and, possibly polarization means configured to provide illumination light on a region of tissue. Detection means are optically coupled to the illumination means, the detection means being adapted to detect reflected light from the tissue (and its polarization state, if applicable) when the tissue is illuminated by the illumination means. Filtering means are optically coupled to the detection means. The filtering means are configured to filter the illumination light and/or reflected light to pass only light within a range, or any subrange between about 1050 to about 1400 nm. Methods for imaging cancer contrast cancer tissue against adjacent healthy tissue. | 03-19-2009 |
20090088649 | PROBE DEVICE - A probe device includes a sheet-like probe holder, a plurality of light-emitting probes and a plurality of detection probes mounted on the probe holder at a predetermined interval, a sheet holding unit holding the probe holder at a predetermined position on the biological surface, and a fixing band mounting the sheet holding unit on the living body. Each of the plurality of light-emitting probes and the detection probes includes a probe body including a light emitting unit or a detection unit, and a probe mounting part detachably mounting the probe body to the probe holder at a predetermined position. | 04-02-2009 |
20090093727 | BIOIMAGING APPARATUS - To improve image quality as well as considering miniaturization. In the top surface | 04-09-2009 |
20090093728 | Vasculature and lymphatic system imaging and ablation associated with a reservoir - Devices, methods, and systems related to imaging and ablation are disclosed. | 04-09-2009 |
20090099457 | Health Indicator - A health indicator device comprising a body scanner to obtain a three-dimensional model of a person, a body volume calculator for calculating the volume of at least a first part of the person's body and a second part of a person's body from the three-dimensional model and a health calculating device for calculating an indication of the person's health based on the output from at least the body volume calculator. | 04-16-2009 |
20090118623 | Instrument and Method for High-Speed Perfusion Imaging - A high-speed laser perfusion imaging instrument including a laser source, a detector, a signal-processing unit, data memory, and a screen to display results. A section of a sample surface is illuminated with laser light; reemitted light from the irradiated surface is collected by focusing optics on a 2D array of integrating photodetectors having elements that can be accessed individually or in a pre-defined selection of pixels at high speed. This 2D array measures intensity variations at each individual pixel. Average amplitude and mean frequency of the measured signal contain information about concentration and speed of moving blood cells. For real-time imaging, exposure time is used as a parameter to measure relative perfusion changes. These data are stored and processed with the signal-processing unit to deliver 2D flow maps of the illuminated sample section, and allow a simple overlay between a conventional image and processed flow maps. | 05-07-2009 |
20090118624 | DEVICE FOR ORAL CAVITY EXAMINATION - Described herein is a device used to perform examinations for detection of abnormal epithelial tissue, the device includes a handle portion, a housing and a mirror assembly secured to an end of the housing. The housing has first and second ends and is detachably connectable to the handle. The housing defines an interior and an opening that communicates the interior with an exterior of the housing when the handle and housing are connected. | 05-07-2009 |
20090124909 | Medical system and method for visualizing regions being monitored in a medical system - The invention relates to a medical diagnostic or therapy system comprising a system controller and at least one moving apparatus component, comprising a contour detecting unit which is constructed for detecting the position of components of the diagnostic or therapy system, and at least one projector that is decoupled from the contour detecting unit and is constructed for visualizing the region being monitored in which the component of the diagnostic and/or therapy system scanned by the contour detecting unit is arranged. The invention also relates to a method for visualizing regions being monitored in a medical diagnostic or therapy system of this kind. | 05-14-2009 |
20090131800 | MULTIMODAL IMAGING SYSTEM FOR TISSUE IMAGING - An apparatus for obtaining area images and optical coherence tomography (OCT) image of a tissue comprises an image sensor, a first illumination means providing broadband polarized polychromatic light, a second illumination means providing narrow-band ultraviolet light, a third illumination means providing Near-Infrared light, an optical coherence tomography (OCT) imaging apparatus, one or more polarization elements, and an optical filter. An image processor identifies a region of interest according to area image, which can be a polarized reflectance image, a fluorescence light image, or both for the OCT imaging apparatus to obtain an OCT image over the region of interest. | 05-21-2009 |
20090137908 | MULTI-SPECTRAL TISSUE IMAGING - Apparatus and methods are disclosed for multi-spectral imaging of tissue to obtain information about the distribution of fluorophores and chromophores in the tissue. Using specific spectral bands for illumination and specific spectral bands for detection, the signal-to-noise ratio and information related to the distribution of specific fluorophores is enhanced as compared to UV photography, which uses a single RGB image. Furthermore, the chromophore distribution information derived from the multi-spectral absorption images can be used to correct the fluorescence measurements. The combined fluorescence, absorption, and broadband reflectance data can be analyzed for disease diagnosis and skin feature detection. | 05-28-2009 |
20090137909 | METHOD FOR IMAGING AND TREATING ORGANS AND TISSUES - The present invention provides methods and compositions for detecting and treating malignant tissue, organs or cells in a mammal. The method comprises parenterally injecting a mammalian subject, at a locus or by a route providing access to the tissue or organ, with a composition comprising an antibody/fragment that is tagged with a fluorophore and a therapeutic isotope molecule, which specifically binds to the targeted organ, tissue or cell. | 05-28-2009 |
20090143685 | Method and Apparatus for Detecting Diseases Associated with the Eye - Disease may be detected, monitored, etc. by detecting metabolic dysfunction in a patient's eyes. In one embodiment of an apparatus, an excitation light is generated by an excitation light source to induce autofluorescence in an ocular tissue (e.g., retinal tissue), wherein the excitation light excites flavoprotein autofluorescence (FA) and minimizes the excitation of non-flavoprotein autofluorescence. At least a single image representing the induced ocular tissue autofluorescence is captured. The at least single image is intensified to increase the signal strength of the ocular tissue autofluorescence. The at least single image is analyzed to generate an indicator of whether a patient has one or more of eye damage, a disease that causes eye damage, or to generate an indicator of the progression of a disease, an indicator of the effectiveness of a treatment, a personalized treatment for a subject, etc. | 06-04-2009 |
20090149761 | PHOTOACOUSTIC IMAGING METHOD - This invention discloses a method to position, identify and characterize a photoacoustic source in a complex environment. This method isolates individual acoustic responses from interferences by spectral analysis and filtering and locates primary acoustic sources by applying beam-forming to decomposed acoustic responses. The photon-absorbing structure of a tissue can be constructed with primary source parameters. | 06-11-2009 |
20090177094 | SYSTEMS AND METHODS FOR TISSUE EXAMINATION, DIAGNOSTIC, TREATMENT, AND/OR MONITORING - Procedures, techniques, and systems for in vivo monitoring, diagnosis, and treatment of tissue during the same or concomitant medical procedure. In disclosed embodiments, during a same or concomitant procedure or examination, tissue can be scanned on a localized level using a real-time optical biopsy system. The real-time optical biopsy system may involve angle-resolved and/or Fourier domain low coherence interferometry (LCI). Because the scanning can be performed in real-time, diagnosis can also be performed in real-time and during the same or concomitant medical procedure. As a result, therapy, if needed, can also be administered to the tissue during the same or concomitant medical procedure. Monitoring of the tissue after therapy can be performed during the same or subsequent procedure. Thus, the procedures and techniques disclosed herein allow detection of tissue anomalies during a first procedure on the patient without waiting for untimely biopsy results, thus providing earlier anomaly detection and treatment and potentially better and timely results and at a lower cost. | 07-09-2009 |
20090187109 | METHOD AND APPARATUS FOR EXAMINING TISSUE FOR PREDEFINED TARGET CELLS, PARTICULARLY CANCEROUS CELLS, AND A PROBE USEFUL IN SUCH METHOD AND APPARATUS - A method, apparatus and probe for examining tissue for the presence of target cells, particularly cancerous cells, by subjecting the tissue to be examined to a contrast agent containing small particles of a physical element conjugated with a biological carrier selectively bindable to the target cells. Energy pulses are applied to the examined tissue. The changes in impedance and/or optical characteristics of the examined tissue produced by the applied energy pulses are detected and utilized for determining the presence of the target cells in the examined tissue. In a described preferred embodiment, the applied energy pulses include laser pulses, and the physical element conjugated with a biological carrier is a light-sensitive semiconductor having an impedance which substantially decreases in the presence of light. The same probe used for detecting the targeted cells may also be used for destroying the cells so targeted. | 07-23-2009 |
20090192390 | Common bile duct surgical imaging system - A method and apparatus for imaging features of a CBD in a patient introduces a fluorescent contrast agent into the CBD. A light source transmits both a visible light and a fluorescent light into a patient's abdominal cavity via the laparoscope. Cameras attached to or integrated into the laparoscope detect visible light images and fluorescent emission light images. The visible light image and fluorescent image signals are processed to combine the fluorescent emission light image signals and visible image signals into a single display signal. The system adjusts the display characteristics, such as color, of the fluorescent emission light image so it contrasts well with the visual light image so the surgeon can easily distinguish between the two images. The display signal is sent to a video monitor where the surgeon views the visible light image and the fluorescent image as a single overlaid image. | 07-30-2009 |
20090204009 | MEDICAL DEVICE SYSTEM AND RELATED METHODS FOR DIAGNOSING ABNORMAL MEDICAL CONDITIONS BASED ON IN-VIVO OPTICAL PROPERTIES OF TISSUE - A diagnostic system detects abnormal physical properties of tissue in a patient based upon optical properties of the tissue. A probe includes light delivery and capture fibers, and polarizers. Optical properties detected relate to polarized and unpolarized light into, and scattering from, the tissue. The optical properties detected are processed and analyzed to produce results indicative of the physical property(s) evaluated. System operation is controlled against pressure monitored via a pressure sensor coupled to the probe-tissue interface. The analysis corrects for patient physical characteristics as user inputs, such as menopausal or menstrual condition of women patients. Physical properties diagnosed include cervical dysplasia conditions in women patients, such as HSIL, cervical cancer, LSIL, or cervicitis. Analysis and diagnosis is based upon at least one of: ratios between scattered light signals captured from the tissue, slope of intensity over wavelength for scattered light signals captured, and hemoglobin-related parameters in the tissue. | 08-13-2009 |
20090204010 | Vein imaging apparatus - A vein imaging device that is capable of achieving space saving. The vein imaging device includes an imaging section and a guide member. The imaging section images a vein pattern of a palm. The guide member is erected on a periphery of an imaging surface of the imaging section. The guide member guides the position of the palm with respect to the imaging surface of the imaging section, by having a finger brought into contact therewith at a predetermined height position from the imaging surface of the imaging section. | 08-13-2009 |
20090209866 | APPARATUS AND METHOD FOR MEASURING ANATOMICAL OBJECTS USING COORDINATED FLUOROSCOPY - Two fluoroscopic images taken from two different angles of the same anatomical feature are registered to a common three-dimensional coordinate system. A dimension of the anatomical feature is determined by specifying with reference to the two registered fluoroscopic images two constrained points within the three-dimensional coordinate system that correspond to the boundaries of the anatomical feature, and calculating a straight-line distance between the two. Additionally, a three-dimensional virtual model of an implant is projected into each of two, registered fluoroscopic image, and a surgeon manipulates the projections to adjust the size and shape of the virtual model, and thereby determine parameters for the implant. | 08-20-2009 |
20090209867 | METHOD FOR RAPID SCREENING OF MAD COW DISEASE AND OTHER TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES - Methods for diagnosing altered neuropathology in an animal are disclosed, wherein said methods comprise imaging brain, spinal cord, or other neural tissue of the animal, analyzing the appearance of the tissue, and determining whether the appearance of the tissue is altered relative to corresponding unaltered tissue. Also disclosed are methods for diagnosing spongiform encephalopathies in an animal, wherein said methods comprise imaging brain, spinal cord, or other neural tissues of the animal, analyzing the appearance of vacuoles in the tissue, and determining whether the appearance of the vacuoles in the tissue is altered relative to corresponding spongiform encephalopathy-free tissue. Also disclosed are automated methods for diagnosing altered neuropathy and spongiform encephalopathies. | 08-20-2009 |
20090216131 | USE OF SURFACE MOTION TO IDENTIFY MECHANICAL PROPERTIES OF BIOLOGICAL TISSUE - A method and apparatus to obtain information about the mechanical properties of a biological tissue by inducing periodic motion in the tissue, imaging the surface motion of the tissue under induced motion, processing the imaged surface motion to obtain descriptive metrics about the surface motion and relating one or more of these descriptive metrics to obtain information about the mechanical properties of the tissue. | 08-27-2009 |
20090221920 | LOW-COHERENCE INTERFEROMETRY AND OPTICAL COHERENCE TOMOGRAPHY FOR IMAGE-GUIDED SURGICAL TREATMENT OF SOLID TUMORS - A method of forming an image of tissue. The method includes beginning an invasive procedure on a patient exposing tissue. The method then includes acquiring OCT data from the exposed tissue and converting the OCT data into at least one image. The method also includes ending the invasive procedure after the converting of the data. | 09-03-2009 |
20090247881 | IMAGE CAPTURING APPARATUS, IMAGE CAPTURING METHOD, AND COMPUTER READABLE MEDIUM - Provided is an image capturing apparatus comprising a light emitting section that emits light to a subject; a light receiving section that receives light in a first wavelength region and light in a second wavelength region from the subject, the second wavelength region being different from the first wavelength region; a reflectance calculating section that calculates a first reflectance of light in the first wavelength region from the subject and a second reflectance of light in the second wavelength region from the subject, based on the light emitted by the light emitting section and the light received by the light receiving section; and a depth identifying section that calculates a depth, from a surface of the subject, of an object inside the subject that is included in an image resulting from the light received by the light receiving section, based on the first reflectance and the second reflectance. | 10-01-2009 |
20090247882 | LIVING BODY HOLDING DEVICE - A concave accommodating section is formed inside a base body. The accommodating section has a shape substantially the same as the left half of a mouse. The mouse is put in the accommodating section in a lying posture with its left side down such that a surface wall of the accommodating section directly contacts with a body surface of the left half of the mouse. Thus, the mouse and its tumor are held in predetermined positions. The right half of the mouse including a body part of interest is exposed from the accommodating section. | 10-01-2009 |
20090253990 | OPTICAL DIAGNOSIS OF HEMOPHILIC JOINT EFFUSION - Non-invasive systems and methods to distinguish between blood and synovial fluid in patients are described. In one embodiment, the system comprises a patient interface system that can be placed over a swollen joint. A region of the swollen joint is illuminated with radiation. The scattered or transmitted radiation from the region of effusion is collected by a collection system and detected by a radiation detector. The information from the detector is analyzed by an analytic processing system to diagnose the cause of the joint effusion. | 10-08-2009 |
20090259130 | OPTICAL TOMOGRAPHY MEASUREMENT USING AN ADAPTED BRIM FOR THE RECEIVING VOLUME - The invention relates to a device for imaging an interior of a turbid medium comprising: a) a receiving volume for receiving at least a part of the turbid medium, with the receiving volume being bound by a boundary having an opening bound by a brim, b) a light source for irradiating the turbid medium, and c) a photodetector unit for detecting light emanating from the volume as a result of irradiating the turbid medium. The device is adapted such that the brim is arranged for optically coupling the light source to the turbid medium and the turbid medium to the photodetector unit. One embodiment of the invention relates to a device for imaging an interior of a female breast comprising a cup-like receptacle ( | 10-15-2009 |
20090264772 | FASH FLUORESCENCE IMAGING DEVICE FOR DIFFUSE OPTICAL TOMOGRAPHY - A device for imaging an interior of a turbid medium arranged to couple excitation light from a light source ( | 10-22-2009 |
20090270738 | Methods for single-pass volumetric bidirectional blood flow imaging Spectral Domain Optical Coherence Tomography using a modified hilbert transform - The present subject matter relates to in vivo volumetric bidirectional blood flow imaging using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image halfplanes, enabling volumetric bidirectional flow mapping without manual segmentation. | 10-29-2009 |
20090275841 | MULTI-WAVELENGTH DIAGNOSTIC IMAGER - The present invention is a multi-wavelength diagnostic imager. In one embodiment, the present invention includes an apparatus and method for noninvasive evaluation of a target versus a non-target, comprising: one or more light sources having at least one emission spectra directed at the target wherein the position, orientation and intensity of light sources is varied to control near-surface reflectance and are directed at less than the entire target; and one or more detectors positioned to capture light reflected from the target into two or more spatial images of the target at two or more times, wherein the spatial images are used to distinguish between the target and the non-target. | 11-05-2009 |
20090281432 | BIOLOGICAL PATTERN IMAGING DEVICE, BIOLOGICAL PATTERN IMAGING METHOD, AND BIOLOGICAL PATTERN IMAGING PROGRAM - To lighten influences of external light when picking up images of biological patterns. The biological pattern imaging device includes a casing having an opening part on one of surfaces. The opening part is in a size that is about to be covered in a closed state when a biological part is placed thereon. The casing contains a light source for irradiating the biological part placed on the opening part, and an imaging part for picking up an image of the irradiated biological part. | 11-12-2009 |
20090292210 | TASK-LESS OPTICAL MAPPING OF BRAIN FUNCTION USING RESTING STATE FUNCTIONAL CONNECTIVITY - A method for utilizing an optical system for mapping brain function includes determining a time series of light intensity measurements for spatially distributed source and detector pairs, receiving light measurements over a period of time, and producing at least one map of a respective strength of each of a plurality of temporal correlations, wherein the temporal correlations are based on the time series of the spatially distributed source and detector pairs and the light measurements. | 11-26-2009 |
20090292211 | Methods and Apparatus for Optical Spectroscopic Detection of Cell and Tissue Death - A method for detecting death process of a cell or tissue of a living subject. In one embodiment, the method includes the steps of illuminating the cell or tissue of the living subject with a coherent light, collecting fluorescent light returned from the illuminated cell or tissue of the living subject, identifying a NAD(P)H peak of a spectrum of the collected fluorescent light with a wavelength, λ | 11-26-2009 |
20090306519 | MEASUREMENT WITH MULTIPLEXED DETECTION - The invention relates to a device ( | 12-10-2009 |
20090306520 | Quantitative methods for obtaining tissue characteristics from optical coherence tomography images - A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values. | 12-10-2009 |
20090312645 | Methods and Devices for Accessing Anatomic Structures - Described herein are methods and devices for performing endoscopic retrograde cholangiopancreatography (ERCP). A system comprising an elongate body housing a front-viewing endoscope and a tissue grasping instrument can be used to facilitate the insertion of a catheter into the ampulla of Vater. The distal end of the elongate body can be positioned such that the operator of the system can view the ampulla while manipulating the surrounding tissue to ease cannulation of the opening with the catheter. As a result, the procedure can be performed faster and more reliably than in the past. | 12-17-2009 |
20090326382 | OPTICAL IMAGING SYSTEM AND METHOD - A device for determining a concentration-related quantity of a fluorescent contrast agent applied to an object ( | 12-31-2009 |
20090326383 | SYSTEMS AND METHODS FOR HYPERSPECTRAL IMAGING - An apparatus for analyzing a subject including a hyperspectral image module is provided. It is used to identify a suspect region of a subject by using a hyperspectral sensor (for obtaining a hyperspectral image of the subject), a control computer including a processor unit (PU) and a computer readable memory (CRM) (for controlling and is in electronic communication with the sensor), a control software module including instructions stored in the CRM and executed by the PU (for controlling said at least one operating parameter of the sensor), a spectral calibrator module including instructions stored in the CRM and executed by the PU (for applying a wavelength dependent spectral calibration standard constructed for the sensor to a hyperspectral image), and a light source for illuminating the subject. An optional contact probe module is used to collect a signal of the suspect region for medical diagnosis. | 12-31-2009 |
20090326384 | Device With Integrated Multi-Fiber Optical Probe and Methods of Use - Biopsy instruments are integrated with a multi-fiber optical probe adapted to perform diagnostic measurements. In addition to being able to analyze, treat or remove tissue, such integrated devices characterize tissue by measuring the amount of scattering and absorption of light transmitted into the tissue. Each fiberoptic probe has an illuminating fiber that provides a broadband light source for transmission into tissue, and a collecting fiber that collects the light scattered by the tissue and transmits the collected light to a spectrometer. One embodiment is an endoscope-mediated tool with a jaw-type biopsy forceps and a multi-fiber optical probe which is conveyed through a hollow central channel. Another embodiment is an endoscope-mediated tool with a jaw-type biopsy forceps and a plurality of multi-fiber optical probes. Yet another embodiment is an endoscopic polypectomy-type snare catheter with a multi-fiber optical probe located at the tip. | 12-31-2009 |
20100004544 | OPTICAL TOMOGRAPHIC IMAGING PROBE, AND OPTICAL TOMOGRAPHIC IMAGING APPARATUS USING THE SAME - To enable OCT imaging inside a blood vessel without having to block blood flow, through the use of an optical tomographic imaging probe including: a tubular probe outer casing; an optical fiber disposed inside the probe outer casing in an axial direction of the probe outer casing; a plurality of transparent inflatable/deflatable split balloons provided circumferentially across an outer circumferential surface of a transparent portion of the probe outer casing, through which a light beam is to be emitted from the optical fiber towards an measurement object, so as to equally divide the circumferential direction; and a balloon inflating/deflating device that respectively and individually inflates/deflates each split balloon, images are captured by removing only blood from imaging areas without having to block blood flow, and a tomographic image of the entire circumference of the inner wall of the blood vessel is obtained by compositing the images. | 01-07-2010 |
20100016730 | EXAMINATION SYSTEM, REHABILITATION SYSTEM, AND VISUAL INFORMATION DISPLAY SYSTEM - In an examination system including a head mounted display having image pickup devices such as CCDs provided therein and a computer, coordinates of an image to be displayed in the head mounted display can be set object- or body-centered. An image captured by the image pickup device is supplied to the computer where it will be processed in a predetermined manner for display in the head mounted display. | 01-21-2010 |
20100016731 | Hemodynamic Detection of Circulatory Anomalies - The preferred indicator is an injection of indocyanine green dye which is detected and quantified by causing it to fluoresce at a sensor location, for example, at the human ear. Quantification is carried out by using cardiac output procedures and where called for, the Valsalva Maneuver is monitored at a monitor/controller giving visual cues to the patient and operator as to the quality of the necessary exhalation pressure maintenance. | 01-21-2010 |
20100016732 | APPARATUS AND METHOD FOR NEURAL-SIGNAL CAPTURE TO DRIVE NEUROPROSTHESES OR CONTROL BODILY FUNCTION - Method and apparatus for detecting nerve activity of an animal. Some embodiments include outputting a light pulse having a wavelength onto a volume of animal tissue such that the light pulse interacts with active nerves of the tissue; measuring a light signal resulting from the interaction of the light pulse with the tissue; transmitting an electrical signal based on the measured light signal; signal-processing the electrical signal; and outputting a response signal, which can optionally be used to control a prosthetic device, stimulate another nerve, or display/ diagnose a condition. Some embodiments output a plurality of light wavelengths and/or pulses, which are optionally high-frequency intensity modulated. Some embodiments analyze DC, AC, and phase components of signals to spatially resolve locations of neural activity. Some embodiments output light pulse(s) and detect the resultant light from outside a human skull to detect neural activity of human brain tissue inside the skull. | 01-21-2010 |
20100022892 | METHOD AND DEVICE FOR NEURAL USER INTERFACE AND BRAIN ACTIVITY MEASURING DEVICE FOR THE SAME - Disclosed are a brain activity measuring device for determining the user's intention by analyzing brain activities, and a neural user interface (NUI) device including an interface section for executing the user-intended function understood in the brain activity measuring device and outputting the result, wherein the brain activity measuring device includes; a light irradiating section for irradiating photons to the cerebral cortex; a light detecting section for detecting the photons emitted out of the human body after the interaction with the cerebral cortex and detecting a change in physical properties of the photons; and an analyzing section for analyzing the change in physical properties of the photons detected in the light detecting section and generating brain activity data to determine the user's intention. | 01-28-2010 |
20100022893 | SELF-INFLATING BLADDER - The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth. | 01-28-2010 |
20100030084 | DIFFUSE OPTICAL TOMOGRAPHY WITH MARKERS CONTAINING FLUORESCENT MATERIAL - The invention relates to a system, a medical image acquisition system, and a method for imaging an interior of a turbid medium ( | 02-04-2010 |
20100036260 | Oral cancer screening device - An oral cancer screening device | 02-11-2010 |
20100036261 | METHOD AND DEVICE FOR IMAGE GUIDED SURGERY - A fluorometer includes a light source to generate excitatory light toward a tissue, the tissue generating fluorescent light in response to the excitatory light. The fluorometer also includes a light sensor to receive the fluorescent light and generate a digital signal. A processor is connected to the light sensor to receive the digital signal and generate a digital image, and a display displays the digital image. The tissue generates fluorescent light as a result of excitation of at least one intrinsic tissue metabolic product. A method for distinguishing between viable and non-viable tissue using the fluorometer also is described. | 02-11-2010 |
20100041999 | Process for quantitative display of blood flow - A method for the quantitative representation of the blood flow in a tissue or vascular region based on the signal of a contrast agent injected into the blood. In the process, several individual images of the signal emitted by the tissue or vascular region are recorded at successive points in time and are stored. For image areas of stored individual images the respective point in time is determined at which the signal has exceeded a certain threshold value and this point in time is represented for each of the image areas. | 02-18-2010 |
20100042000 | Method for correcting the image data that represent the blood flow - A method for correcting the image data representing the blood flow for the evaluation and quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. Several individual images of the signal emitted by the tissue or vascular region are recorded and stored at successive points in time. At least two individual images are correlated and a shift vector is generated based on the correlation. Thereafter, the image data of the individual images are shifted in relation to each other according to the shift vector. | 02-18-2010 |
20100042001 | Raman Instrument for Measuring Weak Signals in the Presence of Strong Background Fluorescence - A method for measuring a chemical concentration in tissue has two measurement steps. A portion of tissue is illuminated with a first generated light and a second generated light. A first Raman scattered light, corresponding to the first generated light, and a second Raman scattered light, corresponding to the second generated light, are directed to a plurality of light sensors, each light sensor measuring light at a different wavelength, that wavelength being proximate to a wavelength of an expected Raman shift wavelength for the chemical in the tissue. A measurement is obtained from each light sensor, each measurement being specific to the first scattered light and/or the second reflected light to that light sensor. The measurements of the first scattered light and the measurements of the second scattered light are used to calculate a concentration of the chemical in the tissue. | 02-18-2010 |
20100042002 | THREE-DIMENSIONAL IMAGING USING AN INFLATABLE MEMBRANE - The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth. | 02-18-2010 |
20100042003 | SMALL-SCALE DIAGNOSTIC SYSTEM AND DISPLAY CONTROL METHOD - A small-scale diagnostic system and a display control method are provided. In the diagnostic system while image data on a patient is displayed on a screen of a medical image control device, when image data on another patient is received from an image generating device, and the medical doctor wants to display the received image data on the another patient on the screen for examining the image and diagnosing the another patient, the displayed image on the screen can be switched to that of the image data on the another patient by a simple operation of depressing a patient selection button. This enables the medical doctor to perform image diagnosis efficiently in a small-scale facility such as a clinic. | 02-18-2010 |
20100042004 | Method and Apparatus for Multi-spectral Imaging and Analysis of Skin Lesions and Biological Tissues - A multispectral nevoscope that uses specific wavelengths in the visible and infrared spectrum of electromagnetic radiation to transilluminate a skin-lesion or a biological tissue or specimen for imaging and maps multispectral 2-dimensional images into 3-dimensional virtual space for providing 3-D distributions of pre-defined parameters representing the characteristic properties (such as melanin, hemoglobin and deoxyhemoglobin, etc.) of a skin lesion. Methods are disclosed for analyzing and using the characteristic distributions of specific parameters for detection and management of skin-cancers, or characterization of a biological tissue or specimen. | 02-18-2010 |
20100042005 | DETECTING OPTICAL PROPERTIES OF A TURBID MEDIUM - A device for measuring light scattering and absorption properties of a tissue, the device comprising: a probe comprising first and second optical fibers for irradiation and detection. The optical fibers are substantially parallel to each other at the distal end, and are separated by a distance of less than 2 mm, wherein said first and second optical fibers are arranged in said probe at an angle, 6=10 deg. to 45 deg., to the plane perpendicular to the distal end of said probe and wherein the tips of the optical fibers at the distal end are polished parallel to the plane perpendicular to the distal end of said probe. | 02-18-2010 |
20100049056 | METHOD, DEVICE, MEDICAL IMAGE ACQUISITION DEVICE FOR IMAGING AN INTERIOR OF A TURBID MEDIUM WITH DARKNESS LEVEL MEASUREMENT - The invention relates to a method, device, and medical image acquisition device for imaging an interior of a turbid medium. The method comprises the following steps: accommodation of the turbid medium inside a receiving volume ( | 02-25-2010 |
20100056927 | SYSTEM, COMPUTER-READABLE MEDIUM, METHOD, AND USE FOR COMBINED EIPTHELIAL EARLY CANCER DIAGNOSIS AND STAGING | 03-04-2010 |
20100056928 | DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS - A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target. | 03-04-2010 |
20100063402 | IMAGING SPECTROMETER FOR EARLY DETECTION OF SKIN CANCER - An imaging spectrometer provides substantially simultaneous areal spectroscopy and image generation to provide improved analysis of possible skin cancer. | 03-11-2010 |
20100063403 | Therapeutic focused energy delivery - A method and an apparatus adapted to perform three dimensional (3D) position-tracking of a transducer unit comprising a three dimensional (3) target, the 3D target adapted to show a position of the transducer unit, and further adapted to facilitate tracking a tilt angle of the transducer unit; and an optical imager adapted to acquire a two dimensional (2D) target image of the target. | 03-11-2010 |
20100069759 | Method for the quantitative display of blood flow - A method for the quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. Several individual images of the signal emitted by the tissue or vascular region are recorded and stored at successive points in time. For image areas of the individual images, the respective intensities of different points in time are compared and the maximum intensities of the signals are determined for these image areas. The maximum intensities are represented for these image areas. | 03-18-2010 |
20100076319 | Pathlength-Corrected Medical Spectroscopy - Systems and methods for reducing scattering effects and correcting for patient to patient anatomical variability are provided. The scattering coefficient of an individual patient's tissue may be corrected for by examining the DC light levels of light passing through the tissue. By comparing the intensity of the light leaving the emitter with the light that reaches the detector to generate a DC component of the signal, which is representative of the anatomical structures of a patient, the AC component of the light may be corrected for the scattering coefficient of the tissue. By correcting the AC signal to account for the scattering coefficient of an individual patient's tissue, a medical sensor may be calibrated in situ for every patient. | 03-25-2010 |
20100081939 | Technique of mapping sentinel lymph nodes using organic blue dyes combined with fluorescence imaging - This invention pertains to a combined technique using an organic blue dye and fluorescence imaging to map sentinel lymph nodes. The near-infrared fluorescence emitted by the blue dye is displayed by a fluorescent imaging system after being irradiated by an excitation light whose wavelength is no less than 570 nm. The blue dye is one of methylene blue, Evans blue, isosulfan blue, patent blue, or a combination of them. The invention solves the problem that a comparatively large incision on skin is inevitable when traditional method is used to detect tumors for sentinel lymph node mapping. The technique of this invention for mapping the sentinel lymph nodes eliminates the need for surgical management, since the sentinel lymph nodes in deep tissue are observed directly through the near-infrared fluorescence of the blue dye reducing pain of the patient. It is a non-radiation, convenient, fast, and accurate method with high clinical values. | 04-01-2010 |
20100087739 | APPARATUS FOR OPTICAL BODY ANALYSIS - An apparatus for optical body analysis is built with an illumination and detection head, and an optical coupler. The illumination and detection head comprises a light source for illuminating a body portion to analyze through the optical coupler and a detector for receiving light diffusely reflected by the body portion. The optical coupler is mechanically decoupled from the illumination and detection head and is adapted to be in contact with an outer surface of the body portion while the contact between the optical coupler and the body portion minimally affects physical properties of the body portion. The apparatus may further comprise a position unit adapted to adjust the position of the illumination and detection head relative to the optical coupler so that the detector receives through the optical coupler light generated by the light source and diffusely reflected by the body portion. | 04-08-2010 |
20100087740 | COLON POLYP STAGING METHODS - Systems and methods are provided for examination and removal of polyps. Using methods and systems of the present disclosure, one can determine whether a polyp is benign or cancerous in situ. | 04-08-2010 |
20100087741 | METHOD FOR IDENTIFYING MALIGNANCIES IN BARRETT'S ESOPHAGUS USING WHITE LIGHT ENDOSCOPY - A method is described for computing a statistically significant difference between dysplasia and Barrett's esophagus (both with and without inflammatory component) using a discriminate function with diffuse reflectance measurements performed at a minimum of four different wavelengths of 485, 513, 598, and 629 nm. The discriminate function found depends both on local blood fraction volume T | 04-08-2010 |
20100094135 | SYSTEMS AND METHODS FOR PHASE MEASUREMENTS - Preferred embodiments of the present invention are directed to systems for phase measurement which address the problem of phase noise using combinations of a number of strategies including, but not limited to, common-path interferometry, phase referencing, active stabilization and differential measurement. Embodiment are directed to optical devices for imaging small biological objects with light. These embodiments can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. The structure and dynamics of sub-cellular constituents cannot be currently studied in their native state using the existing methods and technologies including, for example, x-ray and neutron scattering. In contrast, light based techniques with nanometer resolution enable the cellular machinery to be studied in its native state. Thus, preferred embodiments of the present invention include systems based on principles of interferometry and/or phase measurements and are used to study cellular physiology. These systems include principles of low coherence interferometry (LCI) using optical interferometers to measure phase, or light scattering spectroscopy (LSS) wherein interference within the cellular components themselves is used, or in the alternative the principles of LCI and LSS can be combined to result in systems of the present invention. | 04-15-2010 |
20100106024 | Method for diagnosing vulvovaginal disorders - A method for diagnosing the presence of a vulvovaginal disorder is provided. The method uses a source of cross-polarized light to detect subsurface irritation in the vulvovaginal area. The presence of subsurface irritation is then used to diagnose the presence of a vulvovaginal disorder. | 04-29-2010 |
20100106025 | METHODS FOR OPTICAL IDENTIFICATION AND CHARACTERIZATION OF ABNORMAL TISSUE AND CELLS - An optical system and apparatus for the diagnosis of a biological sample is disclosed. An embodiment of the apparatus includes an optical probe, a probe head distally connectable to the optical probe, the optical probe further comprising at least one optical element for applying an electromagnetic radiation of a first wavelength to the biological sample, and one or more collection elements positioned proximate the at least one optical element; and an analyzer for analyzing a signal received from the biological sample by the one or more collection elements. | 04-29-2010 |
20100106026 | OPTICAL IMAGING OF INDUCED SIGNALS IN VIVO UNDER AMBIENT LIGHT CONDITIONS - A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals form the detector, and passes these signals to memory for accumulation and storage, and then to image processing engine for determination of the localization and distribution of the contrast agent. The computer also provides an output signal based upon the localization and distribution of the contrast agent, allowing trace amounts of the target tissue to be detected, located, or images. A system for carrying out the method is also described. | 04-29-2010 |
20100113940 | WOUND GOGGLES - Appropriate assessment of wound oxygenation is critical to establish a diagnosis, to monitor the effect of the treatment, to guide the therapeutic process, to identify the presence of infection, and to predict the treatment outcome. Embodied systems and methods represent an enabling technology for noninvasive and objective assessment of wound tissue oxygenation. In addition to wound healing, disclosed embodiments offer low cost and portable avenues for noninvasive assessment of multiple clinical parameters for the detection and intervention of various malignancies in multiple soft tissue systems. | 05-06-2010 |
20100121198 | Multi-Purpose Illumination System And Method For Tissue Examination - The present invention is a multi-purpose light source of a unique design and specialized attachments. The invention encompasses a system for the illumination and visual detection of normal and abnormal biologic tissue comprising a light source, a light transmitting device and a light viewing device wherein said device allows for the simultaneous illumination and viewing of target tissue. | 05-13-2010 |
20100121199 | Method and apparatus for non-invasive cancerous tissue diagnosis and tomography using terahertz image - The primary objective of the present method and apparatus is to provide a portable and new diagnosis system for quickly and reliably examining tissue conditions. The method uses the most advance miniaturized micro-opto-electro-mechanical systems (MOEMS) system for generating a rapid variable optical delay line to be able of generating wideband terahertz pulses. The method detects and analyzes cancerous tissues by comparing a plurality of spectrum resolved images of suspected tissue without applying harmful agents into the tissue to facilitate interaction with illumination sources. The method employs non-evasive, real time terahertz imaging systems and techniques to diagnose tissue for detecting the presence of cancer. A map showing, which tissue is healthy and which is cancerous can aid in the accurate removal of cancerous tissue. | 05-13-2010 |
20100121200 | DIAGNOSTIC AND PROGNOSTIC ASSISTANCE DEVICE FOR PHYSIOPATHOLOGICAL TISSUE CHANGES - Said device applies in particular to in vivo diagnostic and prognostic assistance for physiopathological changes to biological tissues. It comprises a coherent light source ( | 05-13-2010 |
20100130869 | METHOD AND APPARATUS FOR DISPLAYING A FIELD OF A BRAIN OF A PATIENT AND NAVIGATION SYSTEM FOR BRAIN SURGERY - A method and an apparatus for displaying a part of a brain of a patient is provided. Laser Doppler images are acquired before and after a stimulation. The laser Doppler images comprise information about a blood motion or about a perfusion at the acquired part. Then, the blood motion images acquired before and after the stimulation are compared to identify areas in the brain of the patient which are related to the stimulation. The identified areas are displayed in dependence of topography data representing a topography of the brain. | 05-27-2010 |
20100130870 | METHOD FOR REAL TIME TUMOUR VISUALISATION AND DEMARCATION BY MEANS OF PHOTODYNAMIC DIAGNOSIS - Proposed invention is related to the field of photodynamic therapy and photodiagnosis. Specifically, a new algorithm is presented for visualisation and spatial demarcation of various types of tumours and unhealthy tissue through unsupervised segmentation of the fluorescent multispectral image. Image is acquired through recording of the emission of the tissue illuminated by the light that induces fluorescence in the tumour. For this purpose tissue is treated by photo sensitizer. Algorithm for real time visualisation and spatial demarcation of the tumour by means of the analysis of fluorescent image consists of the recording of the fluorescent image ( | 05-27-2010 |
20100145199 | Cancer Detection System - A cancer detection system ( | 06-10-2010 |
20100145200 | SPATIALLY OFFSET RAMAN SPECTROSCOPY OF LAYERED SOFT TISSUES AND APPLICATIONS OF SAME - The present invention in one aspect relates to a method for surgical margin evaluation of tissues during breast conserving therapy at a surgical site of interest. In one embodiment, the method comprises the steps of acquiring a plurality of spatially offset Raman spectra from the surgical site of interest, identifying tissue signatures from the plurality of spatially offset Raman spectra, and determining surgical margins of the surgical site from the identified tissue signatures. | 06-10-2010 |
20100160789 | System and Method for Determining Volume-Related Parameters of Ocular and Other Biological Tissues - A system and method for determining volume-related parameters of a biological tissue, such as ocular tissue, include a light source for projecting light towards the biological tissue, a receiver for receiving light reflected from the biological tissue at two spectral wavelengths, and an image acquisition system in communication with the receiver for forming an image from the reflected light at each wavelength. A processor applies a mathematical model to the image which compares the absorption of light by the biological tissue at a selected image point at each of the two spectral wavelengths to determine the volume-related parameters, such as the relative thickness and material properties, of the biological tissue at that location. | 06-24-2010 |
20100160790 | WEARABLE PHOTOACOUSTIC VASCULAR IMAGING SYSTEM - A non-invasive wearable imaging apparatus for vascular detection employing photo-acoustic principle is disclosed. Additionally, a wearable micro-display component is also described. The method includes pulsed laser as an energy source at a wavelength range at which both the blood and the adjoining tissue absorb the light and convert the energy into kinetic energy which heats the tissue. The temperature of the tissue rises and falls in sympathy with the frequency of the impinging light. The alternative heating and cooling of the illuminated region causes alternating sympathetic expansion and contraction of the region with corresponding rising and falling of the tissue surface and of the air in contact with the surface, thereby generating sound waves. A sensor enables the differentiation between the venous and surrounding tissues from which imaging of the venous tissue is extracted. In addition to the acoustic sensors, the sympathetic rising and falling of the tissue surface are converted into color characteristic signals representative of the relative displacement of the tissue surface. Additionally, the differential heating of the tissues enables the visual detection of the venous tissues by appropriate filter lenses. These embodiments also present miniaturization of the generation, imaging and display components, enabling the detection of the blood vessels in a wearable form factor. | 06-24-2010 |
20100160791 | PORCINE BILIARY TRACT IMAGING - The present invention includes apparatus and method to prevent surgical injury. The invention incorporates near infrared (NIR) spectroscopy, which capitalizes on near infrared light's ability to penetrate deeply into tissues and spectroscopic capability to discern tissue's chemical properties. The present invention further characterized the NIR optical properties of bile containing structures as a clinically useful probe. | 06-24-2010 |
20100168585 | PERSONAL AUTHENTICATION METHOD AND PERSONAL AUTHENTICATION DEVICE UTILIZING FINGER-TIP BLOOD FLOW MEASUREMENT BY LASER LIGHT - A personal authentication method is provided that includes imaging, on an image sensor as a laser speckle using an optical system, light reflected from a blood vessel layer in subcutaneous and internal tissues when a laser beam is expanded and made to irradiate a finger pad, calculating a quantity that represents the rate of change with respect to time of the amount of light received for each pixel of the laser speckle, obtaining a finger pad blood flow map as a two-dimensional map of the numerical values, and comparison-checking the blood flow map against pre-registered data of individuals, wherein using a near-infrared laser beam or using this in combination with a visible laser beam, comparison-checking against pre-registered data of individuals is carried out using a pattern reflecting a fingerprint occurring within the finger pad blood flow map obtained from reflected light and, observed superimposed thereon, an internal tissue blood flow distribution pattern, and there is also provided a device used for the method. | 07-01-2010 |
20100168586 | Optical imaging or spectroscopy systems and methods - Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM). | 07-01-2010 |
20100179435 | NONINVASIVE MEASUREMENT OF FLAVONOID COMPOUNDS IN BIOLOGICAL TISSUE - Methods and apparatus are disclosed which facilitate the rapid, noninvasive and quantitative measurement of the concentration of flavonoid compounds, as well as their isomers and metabolites, in biological tissue such as human skin. Low-intensity, visible-light illumination of intact tissue provides for high spatial resolution, and allows for precise quantification of the flavonoid levels in the tissue. The preferred embodiments malce use of a previously unknown, low-oscillator strength, optical absorption transition of flavonoids. This malces it possible to optically excite flavonoids in living human tissue outside the absorption range of other, potentially confounding skin chromophores. A system constructed in accordance with the invention includes a source of light for illuminating a localized region of tissue with light that overlaps the absorption bands of a flavonoid compound; a device for detecting the fluorescence emitted by the flavonoid compound resulting from the illumination; and a processor for determining the concentration level of the flavonoid compound based upon the detected fluorescence. | 07-15-2010 |
20100179436 | OPTICAL SYSTEM FOR DETECTION AND CHARACTERIZATION OF ABNORMAL TISSUE AND CELLS - An optical system and apparatus for the diagnosis of a biological sample is disclosed. An embodiment of the apparatus includes an optical probe, a probe head distally connectable to the optical probe, the optical probe further comprising at least one optical clement for applying an electromagnetic radiation of a first wavelength to the biological sample, and one or more collection elements positioned proximate the at least one optical element; and an analyzer for analyzing a signal received from the biological sample by the one or more collection elements. | 07-15-2010 |
20100191125 | APPARATUS AND METHOD FOR OBTAINING GEOMETRICAL DATA RELATING TO A CAVITY - Disclosed is an apparatus for obtaining geometrical data relating to an internal surface of a cavity. The apparatus comprises a probe having an end portion insertable into the cavity in a direction of insertion, radiation directing means for directing electromagnetic radiation from the end portion to at least one location on the internal surface to cause the radiation to be reflected from said location, detection means for detecting the reflected radiation from the at least one location, and means for determining from the detected radiation a distance between the probe and the internal surface in a direction having at least a transverse component relative to the direction of insertion. The radiation directing means is adapted to direct the radiation at an acute angle relative to the direction of insertion. | 07-29-2010 |
20100198079 | METHOD AND DEVICE FOR EASY ACCESS TO VASCULAR GRAFT CANNULATION SITES - The present invention relates to a polymeric venous implant wherein at least a portion of the graft is made from a UV fluorescing polymer which allows the user to see the graft during access use. This allows the graft to be injected much easier by the ability of the technician to find the graft or a stick site on the graft. | 08-05-2010 |
20100204584 | METHOD AND APPARATUS FOR OCULAR SURFACE IMAGING - The invention provides apparatuses and methods for detecting corneal surface defects. The methods and/or an apparatus of the invention can be used to detect corneal surface diseases, such as dry eye. | 08-12-2010 |
20100210951 | Optical System for Imaging of Tissue Lesions - The present disclosure, according to one embodiment, relates to an optical device for direct visualization, imaging, and spectroscopic measurements of tissue abnormalities at various anatomical sites. Such sites include, but are not limited to, the oral cavity, the cervix, and the skin. In one embodiment, the device comprises: a frame; at least one light-emitting diode light source mounted on the frame for illuminating a tissue, wherein the at least one light-emitting diode light source is chosen from a fluorescent light source, a polarized white light source, and an unpolarized white light source; at least one loupe mounted on the frame for visually observing the tissue; at least one filter disposed between the tissue and the loupe for filtering light reflected from the tissue; and an energy source operably connected to the at least one light-emitting diode light source. | 08-19-2010 |
20100210952 | OPTICAL INSPECTION DEVICE, ELECTROMAGNETIC WAVE DETECTION METHOD, ELECTROMAGNETIC WAVE DETECTION DEVICE, ORGANISM OBSERVATION METHOD, MICROSCOPE, ENDOSCOPE, AND OPTICAL TOMOGRAPHIC IMAGE GENERATION DEVICE - An optical inspection device | 08-19-2010 |
20100217129 | ANGIOGENESIS MONITORING USING IN VIVO HYPERSPECTRAL RADIOMETRIC IMAGING - This invention relates to the use of in-vivo hyperspectral imaging to monitor angiogenesis. Specifically, the invention provides systems and methods of obtaining hyperspectral images of a field of view comprising an area sought to be monitored. | 08-26-2010 |
20100217130 | DEVICE FOR THE PRODUCTION OF PHOTOGRAPHIC IMAGES IN THE MOUTH REGION - The invention relates to a device for the standardized and reproducible measurement and/or photography of the head, or of head regions, particularly of the intraoral region, characterized in that said device comprises—a cranial support ( | 08-26-2010 |
20100222684 | Estimating Physical Parameters Using Three Dimensional Representations - Methods, systems, and apparatus for estimating physical parameters using three dimensional representations. In one aspect, predetermined light patterns are projected onto an object and light patterns resulting from an interaction of the projected light patterns and portions of the object are detected. Three dimensional locations of multiple light elements in the detected light pattern are determined, and physical parameters of the object, for example, weight, are estimated based on the locations. | 09-02-2010 |
20100234738 | DIAGNOSTIC SYSTEMS AND METHODS UTILIZING PROBE-IONS EXHIBITING PHOTON AVALANCHE EFFECT - The present disclosure provides advantageous systems and methods for significantly increasing the sensitivity and selectivity for diagnostic procedures, e.g., optical biopsy. The disclosed systems and methods use a highly non-linear effect, the so-called photon avalanche. In the regime close to the avalanche threshold, small differences in density of the probe-ion under investigation or the excitation power can result in very large changes in up-conversion emission intensity. Through this effect, it becomes possible to accurately measure the signal of an optical biopsy probe-ion only in the location(s) where its concentration is highest, while at the same time significantly reducing or eliminating measurement of background signal from probe-ions distributed with a somewhat lower concentration throughout the measurement volume. Also background auto-fluorescence of the surrounding healthy tissue is essentially absent with this technique. | 09-16-2010 |
20100234739 | SPECTROSCOPIC OBSERVATION DEVICE, ENDOSCOPE SYSTEM, AND CAPSULE ENDOSCOPE SYSTEM - A spectroscopic observation device enables proper observation by respectively meeting the observation condition where easy-to-observe image with high S/N ratio is preferable and the observation condition where it is preferable to restrain interfusion of any other fluorescent components, even when fluorescence of the same wavelength is to be observed. The spectroscopic observation device comprises: an excitation light source ( | 09-16-2010 |
20100234740 | Method and Apparatus for Evaluating Ocular Tissue Conditions - Methods and apparatus are provided for evaluating an ocular tissue condition of a patient (e.g., a disease, a risk of developing a disease, etc.). For example, an indicator associated with the ocular tissue condition may be generated. A portion of ocular tissue of the patient is irradiated using a light source. Light from the portion of the ocular tissue is received. Raman spectra information associated with the received light is determined. An indicator of an ocular tissue condition is generated based at least on the Raman spectra information. The indicator may, for example, assist a physician in diagnosing or ruling out the ocular tissue condition. | 09-16-2010 |
20100241006 | APPARATUS FOR DETECTING BRAIN CONDITIONS - Disclosed embodiments relate to an apparatus for detecting brain conditions. The apparatus for detecting brain conditions may include: a layer which is located adjacent to the brain of a living body; a light source which is formed on the layer and irradiates light to the brain; and an optical sensor which is formed on the layer adjacent to the light source and detects the light scattered from the brain. Since detection is possible at a location relatively adjacent to the brain, the apparatus for detecting brain conditions may improve accuracy and reliability of detection. The apparatus for detecting brain conditions may be used to detect brain conditions such as cerebral oxygenation, cerebral blood volume, cerebral blood flow, etc. or to monitor brain activities, or to diagnose and/or localize the disease foci in case of neurovascular disease such as stroke including hemorrhage or bleeding, into or around the brain or brain tumors or epilepsy, etc. Since the apparatus for detecting brain conditions has a relatively flexible structure, damage to the brain tissue may be minimized. | 09-23-2010 |
20100241007 | Precision measuring system - A non-invasive imaging and analysis method and system/apparatus suitable for non-invasive imaging and analysis of a target is disclosed. Targets include biological tissue structures or components; optical structures or components; electronic structures or components; or structures in general. A preferred embodiment of the invention provides a precision optical measuring module that modifies the spatial separation of multiple reference interference signals by adjusting the separation between a partial reflective element and a full mirror mounted on a piezo device and determining the distance between surfaces or structures within the target by simultaneously monitoring the magnitude of the separation between the partial reflective element and the full mirror and processing generated interference signals. Techniques for simultaneously monitoring the magnitude of the separation between the partial reflective element and the full mirror include conventional measurement techniques, such as, capacitive, optical, or strain techniques or alternatively the use of one or more etalons. Another embodiment of the invention provides a system and method of precisely measuring the position of a surface of interest. | 09-23-2010 |
20100249607 | QUANTITATIVE SPECTROSCOPIC IMAGING - The present invention relates to a fully quantitative spectroscopy imaging instrument for wide area detection of early cancer (dysplasia). This instrument provides quantitative maps of tissue biochemistry and morphology, making it a powerful surveillance tool for objective early cancer detection. The design, construction, calibration, and diagnostics applications of this system is described with the use of physical tissue models. Measurements were conducted on a resected colon adenoma, and the system can be used for vivo imaging in the oral cavity. | 09-30-2010 |
20100249608 | Optical examination device, system and method - As part of an examination device, an input or output optical coupler device for transmitting photons between an optical source or detector and an examined body part includes an array of optical fibers with end portions freely protruding as cantilevers from a support. The optical fibers have the end portions fabricated, sized and distributed to penetrate freely extending hair when the support is placed on the head or other surface of a subject to make optical contact directly over an array of points with the surface of the scalp or skin below the free hair. | 09-30-2010 |
20100249609 | MEASUREMENT OF NEURAL FUNCTIONALITY USING PHASE SENSITIVE OPTICAL COHERENCE REFLECTOMETRY - Optical methods, devices, and systems for noninvasively detecting transient surface displacements in a neuron are disclosed. Methods, devices, and systems provided may employ a phase-sensitive optical low coherence reflectometer. In addition, surface displacements due to action potential propagation in neural tissues may be detected in some embodiments using back-reflected light. According to some embodiments, exogenous chemicals or reflect ion coatings are not required. Transient neural surface displacement of less then 1 nm in amplitude and 1 ms in duration may be detected and may be generally coincident with action potential arrival to the optical measurement site. The systems and methods may be used for noninvasive detection of various neuropathies such as retinal neuropathies. They may also be useful in detecting the effects of various pharmacological agents. | 09-30-2010 |
20100249610 | Modular headrest and multi-light apparatus - A multi-light apparatus ( | 09-30-2010 |
20100262017 | MULTI-CHANNEL MEDICAL IMAGING SYSTEM - A medical imaging system provides simultaneous rendering of visible light and fluorescent images. The system may employ dyes in a small-molecule form that remain in a subject's blood stream for several minutes, allowing real-time imaging of the subject's circulatory system superimposed upon a conventional, visible light image of the subject. The system may provide an excitation light source to excite the fluorescent substance and a visible light source for general illumination within the same optical guide used to capture images. The system may be configured for use in open surgical procedures by providing an operating area that is closed to ambient light. The systems described herein provide two or more diagnostic imaging channels for capture of multiple, concurrent diagnostic images and may be used where a visible light image may be usefully supplemented by two or more images that are independently marked for functional interest. | 10-14-2010 |
20100262018 | METHOD OF CONTROLLING A DEVICE FOR IMAGING THE INTERIOR OF TURBID MEDIA, DEVICE FOR IMAGING THE INTERIOR OF TURBID MEDIA AND COMPUTER PROGRAM PRODUCT - A method of controlling a device for imaging the interior of turbid media is provided. The device comprises: a receiving portion ( | 10-14-2010 |
20100262019 | METHOD AND APPARATUS FOR DETERMINING TARGET DEPTH, BRIGHTNESS AND SIZE WITHIN A BODY REGION - A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originate from the light-emitting source, (ii) travel through turbid biological tissue of the subject, and (iii) are emitted from a first surface region of interest of the subject. The light-intensity profile is matched against with a parameter-based biophotonic function, to estimate function parameters such as depth and size. The parameters so determined are refined using data other than the first measured light intensity profile, to obtain an approximate depth and size of the source in the subject. Also disclosed is an apparatus for carrying out the method. | 10-14-2010 |
20100268090 | MEASUREMENT OF HEMATOCRIT AND CARDIAC OUTPUT FROM OPTICAL TRANSMISSION AND REFLECTION CHANGES - A system and method of non-invasive determination of hematocrit change from optical reflected light in combination with transmitted light or from reflected light measured from one or more locations on a blood carrying medium. Determining the cardiac output of a patient based on the amount of plasma or saline injected and the determined hematocrit change. The cardiac output may be determined on a patient undergoing hemodialysis. The hematocrit changes can be detected transcutaneously, transarterially, intraarterially, or across an extracorporeal arterial circulatory path. | 10-21-2010 |
20100286529 | NEAR INFRA RED FLUORESCENCE IMAGING FOR VISUALIZATION OF BLOOD VESSELS DURING ENDOSCOPIC HARVEST - Endoscopic identification and dissection of a blood vessel in tissue during endoscopic harvest can be enhanced by injecting a bolus of ICG into the bloodstream, illuminating the target vessels with excitation light capable of exciting fluorescence in the ICG, and locating the vessel to be harvested by observing the ICG fluorescence. Moreover, collapsed blood vessel may be harvested by inserting an endoscope into the collapsed blood vessel, injecting into the collapsed blood vessel a bolus containing ICG to re-inflate the blood vessel, illuminating the target vessels with excitation light capable of exciting fluorescence in the ICG; and locating the re-inflated blood vessel by observing the ICG fluorescence. | 11-11-2010 |
20100292580 | SEPTIC BARRIERS AND OTHER AIDS FOR AUTOFLUORESCENCE VISUALIZATION AND OTHER OPTICAL INTERROGATION - Septic barriers interposed between a target tissue such as an oral or vaginal cavity, exposed epidermis, or wound or surgical site, and a user and his/her optical interrogation instruments to reduce cross-infection and/or contamination. In certain embodiments, the septic barrier is substantially transparent for viewing purposes and is typically effectively non-fluorescent, particularly when used for investigating autofluorescence or other fluorescence emanating from a target, so as to have little or no effect on the measurements and observations being made. The sepsis barrier can comprises a window through which the user sees the tissue, a frame holding the window, and an attachment structure, such as threads or bayonet attachment, configured to connect the barrier to the instrument. If desired, the system can also have an optional attachment mechanism for permanent or temporary connection of a further instrument to the frame, such as a tissue retractor configured to aid manipulation of the target tissue. | 11-18-2010 |
20100292581 | Dynamic Calibration of an Optical Spectrometer - A dynamically calibrating optical spectrometer and method for dynamically calibrating the optical spectrometer are provided. The optical spectrometer may include a band-pass device and a device that scans, such that a scan window can be widened, and the edges of the band-pass device can be used to calibrate out drifts in the system. The optical spectrometer may be for acquiring and analyzing a spectroscopic sample of an analyte from a sampling region of the tissue of a person. The optical spectrometer includes a tunable source of electromagnetic radiation, a probe for delivering the electromagnetic radiation to the tissue at the sampling region and obtaining a diffuse reflectance signal from the tissue at the sampling region, a spectroscopic detector for analyzing the diffuse reflectance signal for presence of the analyte, and a wavelength calibration detector for calibrating the tunable source of electromagnetic radiation to a desired wavelength. | 11-18-2010 |
20100298715 | METHOD AND MEASURING INSTRUMENT FOR COLLECTING SPECTROMETRIC TEST SIGNALS FROM LIVING TISSUE - The invention relates to a method and a measuring instrument for collecting spectrometric test signals from living tissue. The aim of the invention is to create solutions which make it possible to generate, in the course of a spectrometric measurement, test results that supply more comprehensive data than previously known recording attempts. Said aim is achieved by a method for generating spectrometric test signals, in which light (L) is injected into a living tissue area (G) to be examined, reflected light (R) emerging from the tissue area to be examined is fed to a spectrometer device, and test signals representing the intensity of the reflected light by associating the same with the wavelength are generated by means of the spectrometer device. The measurement is taken such that the measurement process lasts a certain period of time (T) during which data is generated that represents the time course of the intensity of the resolved wavelengths, thus advantageously making it possible to generate, during the spectrometric measurement, signals which allow specific substances, e.g. the blood components cholesterol and sugar, to be associated with specific zones of the examined tissue area. | 11-25-2010 |
20100298716 | METHODS AND COMPOSITIONS TO REDUCE SCATTERING OF LIGHT DURING THERAPEUTIC AND DIAGNOSTIC IMAGING PROCEDURES - Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention has particular advantages in imaging within the cardiovascular system and highly vascularized or oxygen-dependent tissues. | 11-25-2010 |
20100305452 | OPTICAL COHERENCE TOMOGRAPHY FOR BIOLOGICAL IMAGING - Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle. | 12-02-2010 |
20100305453 | IMAGING OF LIGHT SCATTERING TISSUES WITH FLUORESCENT CONTRAST AGENTS - A system and method for non-invasive biomedical optical imaging and spectroscopy with low-level light is described. The technique includes a modulated light source coupled to tissue to introduce excitation light. Fluorescent light emitted in response to the excitation light is detected with a sensor. The AC intensity and phase of the excitation and detected fluorescent light is provided to a processor operatively coupled to the sensor. A processor employs the measured emission kinetics of excitation and fluorescent light to “map” the spatial variation of one or more fluorescence characteristics of the tissue and generate a corresponding image of the tissue via an output device. The fluorescence characteristic may be provided by exogenous contrast agents, endogenous fluorophores, or both. A technique to select or design an exogenous fluorescent contrast agent to improve image contrast is also disclosed. | 12-02-2010 |
20100305454 | METHOD FOR EVALUATING BLUSH IN MYOCARDIAL TISSUE - Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure. | 12-02-2010 |
20100305455 | DEVICE FOR WAVELENGTH-SELECTIVE IMAGING - An imaging device captures both a visible light image and a diagnostic image, the diagnostic image corresponding to emissions from an imaging medium within the object. The visible light image (which may be color or grayscale) and the diagnostic image may be superimposed to display regions of diagnostic significance within a visible light image. A number of imaging media may be used according to an intended application for the imaging device, and an imaging medium may have wavelengths above, below, or within the visible light spectrum. The devices described herein may be advantageously packaged within a single integrated device or other solid state device, and/or employed in an integrated, single-camera medical imaging system, as well as many non-medical imaging systems that would benefit from simultaneous capture of visible-light wavelength images along with images at other wavelengths. | 12-02-2010 |
20100312122 | SYSTEMS FOR INTRAOPERATIVE NERVE IMAGING - Disclosed are systems for intraoperative nerve imaging using compact high collection power imaging devices for fluorescence and white light imaging of myelin basic protein (MBP) nerve imaging agents during open and minimally invasive surgery. | 12-09-2010 |
20100317974 | DETECTION OF VULNERABLE PLAQUES BY RAMAN SPECTROSCOPY - An apparatus and method of use for detecting vulnerable plaque (VP) in arterial walls is provided. The method includes measuring whether the Raman spectrum of adipose (lipid) tissue signal is present in a Raman signal from aortic intimal wall tissue. The Raman vibration modes for VP are strong bands at about 1435 cm | 12-16-2010 |
20100317975 | METHOD AND SYSTEM OF SPECTRALLY ENCODED IMAGING - A spectrally encoded imaging device having a light transmission path arrangement which propagates light to illuminate a target object, a light collection path arrangement having a light collection waveguide which propagates a spectrally encoded portion of the light from the target object to a detector which forms an image of the target object accordingly, and a diffractive element which spectrally disperses at least one of the light and the spectrally encoded portion. The light transmission path arrangement and the light collection path arrangement are optically isolated from one another. | 12-16-2010 |
20100324426 | Full-Body Laser Scanner and Method of Mapping and Contouring the Body - A full-body non-invasive laser scanner for mapping or measuring a patient's body and for treating a patient's body with laser energy comprises a patient support, one or more laser devices, a laser guidance system, a control center, and optionally feedback sensors. The patient support aids in maintaining body alignment during treatment, and the laser devices are moveably positioned on a laser guidance system such that they can be driven about a stationary patient. To map and contour a patient's body, the patient aligns himself on the patient support. With the control center, an operator chooses whether to map, contour, or map and contour the patient's body either manually or according to preprogrammed treatment protocols. The carriage assembly translates and the laser devices apply laser energy to the surfaces of the patient's body according to the chosen protocol. Feedback sensors provide data for mapping the contours of the patient's body. | 12-23-2010 |
20100331705 | METHOD FOR DETECTING THE PRESENCE OF INHOMOGENEITIES IN AN INTERIOR OF A TURBID MEDIUM AND DEVICE FOR IMAGING THE INTERIOR OF TURBID MEDIA - A method for detecting the presence of inhomogeneities in an interior of a turbid medium ( | 12-30-2010 |
20100331706 | OPTICAL ANALYZER - An optical analyzer performing analysis excellent in spatial resolution and in invasion depth is provided. The analyzer includes a diagnostic light source section including a seed light source which outputs seed light, and a silica optical fiber to which seed light is input and which generates diagnostic light having a HE11 mode field pattern utilizing a nonlinear optical phenomenon, an irradiation optical system converging the diagnostic light and irradiating a measurement subject with the diagnostic light, an acquisition optical system acquiring object light generated at the measurement subject, a spectrum measurement section receiving the object light and measuring a frequency spectrum of the object light, a storage section storing information of a frequency spectrum of a known substance, and an arithmetic section calculating a correspondence between the frequency spectrum of the object light and the frequency spectrum of the known substance, and analyzing the measurement subject based on the calculation result. | 12-30-2010 |
20100331707 | BIOLOGICAL INFORMATION IMAGING APPARATUS, BIOLOGICAL INFORMATION ANALYZING METHOD, AND BIOLOGICAL INFORMATION IMAGING METHOD - A biological information imaging apparatus includes: a light source; an acoustic wave detector that detects an acoustic wave generated from a light absorption material in a living body that has absorbed a part of energy of light irradiated from the light source to the living body, and converts it into a first electric signal; a photodetector that detects optical intensity of a portion of the light irradiated from the light source to the living body and propagating in the living body, and converts it into a second electric signal; and a calculation unit that calculates optical property distribution information on the living body by making use of an analytical result of one of the first electric signal and the second electric signal for analysis of the other electric signal. | 12-30-2010 |
20110004106 | OPTICAL BIOLOGICAL INFORMATION DETECTING APPARATUS AND OPTICAL BIOLOGICAL INFORMATION DETECTING METHOD - An optical biological information detecting apparatus includes a light emitting unit which emits observation light of a specific wavelength band to optically observe a desired portion of a tissue of a skin of a human body, and an annular light guide unit which guides the observation light to a desired area of a surface of the skin corresponding to the desired portion of the tissue of the skin, and which annularly irradiates the observation light onto the desired area of the surface of the skin. The apparatus further includes a light receiving unit which is disposed at a position surrounded by the annular light guide unit, and which receives scattered light scattered by the desired portion of the tissue of the skin after the observation light is annularly irradiated onto the desired area of the surface of the skin by the annular light guide unit. | 01-06-2011 |
20110021925 | Mounted vein contrast enchancer - A vein-image-enhancing system transmits two different wavelengths of laser light, being directed by a steering means, to form a raster pattern on a target. Reflected light comprises a contrasted image formed by a portion of the first wavelength being absorbed by veins, and a portion of that first wavelength being reflected from the target. A photodectector sensitive to the first wavelength captures reflected light. The contrasted image is projected onto the target to illuminate vein locations using the second wavelength, which comprises visible light. Projection may operate according to one of three modes: the alternating frame mode, a dual buffer mode, and real time mode. The AFM and DBM modes incorporate analog to digital converters and digital memory for timed projection onto the target. The vein enhancer may be specially attached to different platforms—hospital bed, IV stand, wheelchair, etc., to enable convenient use of the enhancer on a patient. | 01-27-2011 |
20110028850 | Process for quantitative display of blood flow - A method for the quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. In the method, several individual images of the signal emitted by the tissue or vascular region are recorded at successive points in time and are stored. Based on the respective signal, a quantity characteristic for the blood flow and a quantity characteristic for the position of the blood vessels are determined for image areas of individual images. These quantities are represented superimposed for the respective image areas such that both the blood flow quantity and the position of the fine blood vessels become clearly visible in the representation and can be differentiated from the tissue. | 02-03-2011 |
20110034810 | MULTIPLE IMAGES, MULTIPLE EXPOSURE TIMES, OPTICAL IMAGING OF BLOOD CIRCULATION VELOCITIES - A method of measuring blood velocity includes obtaining a first velocity image by illuminating a tissue surface with a light source for a first exposure time, obtaining a second velocity image by illuminating the tissue surface with the light source for a second exposure time, computing a first average intensity of a first pixel block at a first predetermined location of the first velocity image and a second average intensity of a second pixel block at a second predetermined location of the second velocity image, identifying mid-range velocities of the first and second pixel blocks, computing an optimal optical coherence parameter based on the mid-range velocity of the first pixel block and the mid-range velocity of the second pixel block, and iteratively re-computing the first velocity image and the second velocity image using the optimal optical coherence parameter. | 02-10-2011 |
20110040192 | METHOD AND A SYSTEM FOR IMAGING AND ANALYSIS FOR MOLE EVOLUTION TRACKING - A mole monitoring system including: (a) a calibration fixture including an illuminator that is operational to illuminate a skin area that includes a mole; (b) a digital camera operational to acquire at least one image of a body area that is included in the illuminated skin area and which includes the mole and its environment; and (c) a processor operational to analyze the at least one image of the mole and to determine values for parameters of the mole. | 02-17-2011 |
20110060227 | TISSUE VISUALIZATION AND MANIPULATION SYSTEM - Tissue visualization and manipulation systems are described herein. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue region of interest. | 03-10-2011 |
20110071402 | APPARATUS AND METHOD FOR IRRADIATING A MEDIUM - A method for irradiating a medium includes irradiating the medium with an electromagnetic wave which is scattered in the medium and modulated in frequency at a position in the medium; obtaining information corresponding to an interference pattern generated by interference between the modulated electromagnetic wave and a reference wave; and generating a phase conjugate wave, based on the obtained information, which irradiates the medium. | 03-24-2011 |
20110071403 | FUNCTIONAL NEAR-INFRARED FLUORESCENCE LYMPHATIC MAPPING FOR DIAGNOSING, ACCESSING, MONITORING AND DIRECTING THERAPY OF LYMPHATIC DISORDERS - Methods and imaging agents are used to functionally image lymph structures and to identify, diagnose, assess, monitor and direct therapies for lymphatic disorders. Embodiments of the methods utilize highly sensitive optical imaging and fluorescent spectroscopy techniques capable of rapid temporal resolution to non-invasively track or monitor packets of imaging agents flowing in one or more lymphatic structures in human patients to provide quantitative information regarding lymph propulsion and functionality of the lymphatic structures. An imaging agent comprises a fluorophore labeled peptide capable of binding integrin α | 03-24-2011 |
20110077528 | METHOD AND APPARATUS FOR SIMULTANEOUS HEMOGLOBIN REFLECTIVITY MEASUREMENT AND OCT MEASUREMENT, THROMBUS DETECTION AND TREATMENT, AND OCT FLUSHING - A method and apparatus for simultaneous hemoglobin reflectivity measurement and OCT measurement, thrombus detection and treatment, and OCT flushing. A first optical energy for OCT and a second optical energy for hemoglobin may be used. | 03-31-2011 |
20110077529 | Imaging apparatus - An imaging apparatus includes an illumination light output system that outputs light including wavelength components that are different from each other to living body tissue, an image formation optical system that forms an image of the living body tissue illuminated with the light output from the illumination light output system, and an imaging means that images the living body tissue. The image formation optical system has axial chromatic aberration in which focal length for C line that has a wavelength of 643.8 nm is greater than or equal to 102 when focal length for F line that has a wavelength of 486.1 nm is regarded as 100. | 03-31-2011 |
20110087109 | METHODS AND APPARATUS FOR DETERMINING FALLOPIAN TUBE OCCLUSION - Devices and methods for determining fallopian tube occlusion. The methods may include determining fallopian tube occlusions through a pressurization or volumetric determination. | 04-14-2011 |
20110087110 | MEDICAL IMAGING PROCESSES FOR FACILITATING CATHETER-BASED DELIVERY OF THERAPY TO AFFECTED ORGAN TISSUE - Medical imaging processes are disclosed for facilitating the catheter-based delivery of stem cells or other therapy to affected organ tissue, including myocardial infarct and peri-infarct tissue. The disclosed processes include the integration of static image data showing the affected tissue with a live/moving image (e.g., a fluoroscopy image) to generate a hybrid view showing the real time location of an injection catheter relative to the affected tissue. The static image data may include or be derived from one or more noninvasive nuclear medicine imaging scans (e.g., PET or SPECT) generated prior to the catheterization procedure. The live image may also be augmented with visual markers showing target and/or actual injection locations. Also disclosed are methods for calculating amounts of therapy to deliver to the affected tissue. | 04-14-2011 |
20110087111 | System and Method for Normalized Diffuse Emission Epi-illumination Imaging and Normalized Diffuse Emission Transillumination Imaging - A system and method provide normalized fluorescence epi-illumination images and normalized fluorescence transillumination images. The normalization can be used to improve two-dimensional (planar) fluorescence epi-illumination images and two-dimensional (planar) fluorescence transillumination images. The system and method can also provide normalized bioluminescence epi-illumination images and normalized bioluminescence transillumination images. In some arrangements, the system and method can provide imaging of small animals, intro-operative imaging, endoscopic imaging, and/or imaging of hollow organs. | 04-14-2011 |
20110092823 | System and Method for Identifying Tissue Using Low-Coherence Interferometry - An apparatus for needle biopsy with real time tissue differentiation using one dimensional interferometric ranging imaging, comprising a biopsy device having a barrel and a needle, an optical fiber inserted in the needle, and a fiber optic imaging system connected to the optical fiber. The imaging system obtains images and compares the optical properties and patterns to a database of normalized tissue sample images to determine different tissue types. The physician performing the biopsy obtains feedback via a feedback unit associated with the biopsy device and which is connected to the imaging system. The feedback unit can provide visual, audible or vibratory feedback as to tissue type encountered when the needle is inserted toward the target tissue. The feedback unit can be programmed for different biopsy procedures so that the user can actuate a button to select a display or other feedback mechanism for the desired procedure and anticipated tissue to be encountered. | 04-21-2011 |
20110098575 | METHOD AND AN ARRANGEMENT FOR THE DETERMINATION OF THE OPTICAL PROPERTIES OF A MULTI-LAYERED TISSUE - The present invention relates to a method and an arrangement for the determination of the optical properties of a multi-layered tissue. More specifically, the invention relates to a method for the detection and characterization of tumors in a tissue. | 04-28-2011 |
20110098576 | NON-INVASIVE IMPLANT RUPTURE DETECTION SYSTEM - Devices and methods for non-invasive implant rupture detection are described herein. Some variations of a non-invasive implant rupture detection device comprise a single optical waveguide, such as a silicone fiber, embedded in the shell of the implantable device where one end of the optical waveguide is connected to a photo emitter and the other end of the waveguide is connected to photo detector. An optical signal successfully transmitted from the photo emitter through an intact optical waveguide to the photo detector indicates that the implant shell is intact, while an optical signal that is transmitted by the photo emitter, but not detected by the photo detector, indicates that there is a discontinuity or rupture in the shell. The status of the implant shell is wirelessly communicated to an external reader and provided to a patient and/or a practitioner. | 04-28-2011 |
20110098577 | REGISTRATION POINTER AND METHOD FOR REGISTERING A BONE OF A PATIENT TO A COMPUTER ASSISTED ORTHOPAEDIC SURGERY SYSTEM - A registration pointer includes a camera located in an elongated shaft having a distal end configured to be contacted to a bone of a patient to register the bone to a computer assisted orthopaedic surgery system. The camera may be a hemispherical camera and may include a panoramic camera and a wide-angle camera equipped with a fish-eye lens. The registration pointer is configured to transmit images received by the cameras to the computer assisted orthopaedic surgery system for display thereon. The computer assisted orthopaedic surgery system may be configured to generate an image, such as a hemispherical image, based on the images received from the registration pointer. | 04-28-2011 |
20110098578 | OPTICAL IMAGING OF RHEUMATOID ARTHRITIS - The present invention concerns the use of indocarbocyanine dyes, in particular indotricarbocyanine dyes for the diagnosis of inflammatory diseases, in particular rheumatoid arthritis, methods of diagnosing inflammatory diseases and an apparatus useful to carry out the method of diagnosing. | 04-28-2011 |
20110112407 | Multispectral detection and presentation of an object's characteristics - An apparatus for capturing a multispectral image of an object is described. The apparatus includes one or more means for transmitting a beam of laser light at a first wavelength and a beam of laser light at one or more additional wavelengths different from the first wavelength. There is a means for causing the beams of laser light to travel in a coaxial path and a moving mirror. The beams of light bounce off the mirror thereby producing a two dimensional projection pattern. This pattern travels from the mirror along a first path to an object and wherein some of the laser light penetrates the object and travels to an internal structure of the object. The reflection of the laser light returns to a photo detector along a path different from said first path. | 05-12-2011 |
20110112408 | Optical Speculum - A system for direct imaging and diagnosing of abnormal cells in a target tissue includes a disposable optical speculum and an image acquisition system having the speculum assembled on and mechanically secured thereto. The image acquisition system is arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets. An image analysis and control unit in communication with the image acquisition system analyzes the data sets and applies algorithms to the data sets for diagnosing abnormal cells. | 05-12-2011 |
20110118609 | Imaging Surgical Target Tissue by Nonlinear Scanning - Systems and techniques for laser surgery based on imaging a target tissue by nonlinear scanning are presented. In one implementation, a method for guiding an eye surgery can include the steps of: positioning an eye in relation to an imaging system; creating first scan data by determining a depth of an eye target region at a first set of points along a first arc; creating second scan data by determining a depth of the eye target region at a second set of points along a second arc; determining target region parameters based on the first and second scan data; and adjusting one or more surgical position parameters according to the determined target region parameters. | 05-19-2011 |
20110118610 | AN OPTICAL IMAGE PROBE - The invention relates to an optical image probe( | 05-19-2011 |
20110125028 | Vein scanner - A portable vein viewer apparatus may be battery powered and hand-held to reveal patient vasculature information to aid in venipuncture processes. The apparatus comprises a first laser diode emitting infrared light, and a second laser diode emitting only visible wavelengths, wherein vasculature absorbs a portion of the infrared light causing reflection of a contrasted infrared image. A pair of silicon PIN photodiodes, responsive to the contrasted infrared image, causes transmission of a corresponding signal. The signal is processed through circuitry to amplify, sum, and filter the outputted signals, and with the use of an image processing algorithm, the contrasted image is projected onto the patient's skin surface using the second laser diode. Revealed information may comprise vein location, depth, diameter, and degree of certainty of vein locations. Projection of vein images may be a positive or a negative image. Venipuncture needles may be coated to provide visibility in projected images. | 05-26-2011 |
20110125029 | Targeted Dual-Axes Confocal Imaging Apparatus with Vertical Scanning Capabilities - An optical device is described that may be used as a microscope system for real-time, three-dimensional optical imaging. The device includes a miniature, fiber optic, intra-vital probe microscope that uses a dual-axes confocal architecture to allow for vertical scanning perpendicular to a surface of the sample (e.g., a tissue surface). The optical device can use off-axis illumination and collection of light to achieve sub-cellular resolution with deep tissue penetration. The optical device may be used as part of an integrated molecular imaging strategy using fluorescence-labeled peptides to detect cell surface targets that are up-regulated by the epithelium and/or endothelium of colon and breast tumors in small animal models of cancer. | 05-26-2011 |
20110125030 | MEDICAL DIAGNOSTIC DEVICE AND METHOD OF IMPROVING IMAGE QUALITY OF MEDICAL DIAGNOSTIC DEVICE - A medical diagnostic device is characterized in that an image processing means ( | 05-26-2011 |
20110125031 | DEVICE AND METHOD FOR IN VIVO IMAGING - Devices and methods for optically scanning an in-vivo lumen, and for determining contact between an in-vivo device and an in-vivo lumen wall. The device may include an elongated housing having a cylindrical portion. At least one illuminating body may provide illumination at the circumference of the cylindrical portion, and at least one light sensor may sense light that penetrated and was scattered from the tissue of the in vivo lumen. The device may include means for preventing direct illumination from the illuminating body from reaching the light sensor and for decreasing the amount of direct light reflection from the outer surface of the in vivo lumen onto the light sensor. | 05-26-2011 |
20110125032 | Devices and Methods for the Treatment of Endometriosis - A tissue treatment device comprises an insertion section sized and shaped for insertion into the body via a trocar and a diagnostic element coupled to the insertion section, the diagnostic element illuminating tissue with light of a wavelength selected to facilitate identification of target tissue in combination with an ultrasound element coupled to the insertion section for delivering to a portion of tissue illuminated by the diagnostic element ultrasound energy. | 05-26-2011 |
20110137178 | Devices and methods for imaging particular cells including eosinophils - An exemplary embodiment of apparatus and method according to the present disclosure can be provided. For example, using at least one first arrangement, it is possible to direct at least one first electro-magnetic radiation to at least one portion of tissue within a body. Using at least one second arrangement, it is possible to receive at least one second electro-magnetic radiation provided from the portion, which is based on the first electro-magnetic radiation. Further, using at least one third arrangement, it is possible to differentiate at least one particular cell which is eosinophil, mast cell, basophil, monocyte and/or nutrophil from other cells in the portion based on the second electro-magnetic radiation. | 06-09-2011 |
20110137179 | DIFFERENTIAL LASER-INDUCED PERTURBATION (DLIP) FOR BIOIMAGING AND CHEMICAL SENSING - Methods for imaging or optical sensing of a material are provided. A first fluorescent image or optical signal of a material can be recorded, the material can be perturbed, and then a second fluorescent image or optical signal of the material can be recorded. The two fluorescent images or signals can be subtracted to give a differential image or optical signal. | 06-09-2011 |
20110144503 | Optical methods for monitoring of birefringent tissues - The present invention comprises methods and systems/devices for non-invasively measuring birefringent tissues (e.g. collagen) and changes during treatment of tissue, e.g., denaturation by the application of RF energy, through linear dichroism, circular dichroism, or birefringence. The invention optionally uses polarization sensitive optical measurements to discriminate between denaturation of unidirectionally oriented strands of collagen, such as a ligament or tendon, and denaturation of planar collagen surfaces, such as the dermal layer of the skin or collagen in joint capsules. | 06-16-2011 |
20110144504 | METHOD AND APPARATUS FOR OPTICAL IMAGING VIA SPECTRAL ENCODING - Method, apparatus and arrangement according an exemplary embodiment of the present invention can be provided for generating an image of at least one portion of an anatomical structure. For example, the portion can have an area greater than about 1 mm2, and the image can have a resolution a transverse resolution that is below about 10 μm. For example, light can be scanned over such portion so as to generate first information which is related to the portion, where the light may be provided through a diffraction arrangement to generate a spectrally dispersed line. Method, apparatus and arrangement according to a further exemplary embodiment of the present invention can be provided for positioning a radiation or optical beam within an anatomical structure based on signals generated by scanning a portion of the structure using the same or a different beam. | 06-16-2011 |
20110144505 | OPTICAL DEVICE AND METHOD FOR SHAPE AND GRADIENT DETECTION AND/OR MEASUREMENT AND ASSOCIATED DEVICE - Provided are: an optical device for shape and gradient detection and/or measurement which has a simple structure, is robust to external disturbance, and enables accurate measurement of the gradient angle of an object surface, including a human body; a method for optical shape and gradient detection and/or measurement; and a circularly polarized light illumination device. The optical device for shape and gradient detection and/or measurement uses the optical reflection characteristics of the surface of an object to detect and/or measure the surface shape or gradient of an observed object, and is provided with an illumination device and a polarized light image detection device. The illumination device makes the incident light, which surrounds the periphery of the object and is essentially a known perfect polarized light, fall uniformly. The polarized light image detection device detects a polarized light ellipse of the perfectly polarized light component of a light beam group, which is specularly reflected by the object surface and radiated at a particular azimuth angle. The optical device measures the gradient angle with respect to the radiated light beam of the reflection surface in a step 1 in which the orientation of the incident plane is detected from the observed azimuth angle value of the polarized light ellipse for the reflecting surface of the object which forms an incident point for each reflected and radiated light beam, and a step 2 in which the incident angle is detected from the ellipticity logic value of the polarized light ellipse. The method for optical shape and gradient detection and/or measurement is carried out using the same operation. | 06-16-2011 |
20110152693 | METHOD FOR PRECISELY DETERMINING THE FLUORESCENCE IN A LAYER SYSTEM, SUCH AS THE EYE - The invention relates to a method for precisely determining the fluorescence in a layer system, such as the eye. The object of the invention is to provide a method that is as simple and requires as little effort as possible for evaluating the fluorescence in a layer system, by means of which the summary decay behavior of the fluorescence can be evaluated very precisely, and by means of which the points of origin of the individual fluorescences of the layer system can be determined at the same time. According to the invention, the time of origin (tci) of each fluorescence in the individual layers of the layer system are determined in that layer-specific, time-dependent parameters are determined for the relevant fluorescences, said parameters each indicating the time of origin of the fluorescence in the relevant layer, and said parameters being considered in the model function for calculating the summary decay behavior of the fluorescence. Areas of application are found in the analysis of objects having layer structures, such as in biology, in medicine, and in production engineering. | 06-23-2011 |
20110178409 | Optical Element - A microscope, endoscope or optical coherence tomograph, comprising a light source, a flexible light transmitter ( | 07-21-2011 |
20110178410 | Method of Quantitative Analysis Utilizing Multiphoton Microscopy - The present invention utilizes multiphoton microscopy for a quantitative analysis of a bio tissue or a skin. Multiphoton microscopy is characterized in low invasion, low photo damage and high penetration. Hence, scanning through multiphoton microscopy does not hurt the bio tissue. It is thus fit for scanning live bio tissues to know its aging status. In addition, the quantitative analysis provides a precise index for diagnosing a damage severity of the tissue, like cancer. | 07-21-2011 |
20110178411 | METHOD FOR DETERMINING SKIN GLYCATION - A method for the measurement and analysis of skin fluorescence across multiple subjects. The method includes illuminating each subject with an excitation wavelength, detecting a peak fluorescence level within a corresponding emission wavelength range, determining relative levels of skin glycation for each subject, and evaluating the efficacy of a skin treatment based on the relative levels of skin glycation. The method can include ranking and normalizing the peak fluorescence levels for each subject, and the method is suitable for use in placebo-controlled studies of anti-glycation skin therapies. | 07-21-2011 |
20110184293 | DEVICE, METHOD AND KIT FOR IN VIVO DETECTION OF A BIOMARKER - The invention relates to a device and a system for in-vivo detection of a biomarker in the gastrointestinal tract. The invention further relates to a method for the in-vivo detection of a biomarker in the gastrointestinal tract such as e.g., the α1-antitrypsin precursor (A1AT biomarker), by using the recognition factor, e.g., trypsin immobilized to a solid surface. The invention further relates to a kit for the in-vivo detection of a biomarker in the gastrointestinal system. | 07-28-2011 |
20110190637 | MEDICAL MEASURING SYSTEM, METHOD FOR SURGICAL INTERVENTION AS WELL AS USE OF A MEDICAL MEASURING SYSTEM - The invention relates to a medical measuring system, surgical intervention methods, and the use of a medical measuring system. The measuring system comprises two two-dimensional imaging sensors, a light source that is rigidly connected to the camera system in order to project structured light onto objects, and a structure that has a two-dimensional pattern and is mounted on an object. | 08-04-2011 |
20110190638 | Illumination Apparatus for Use in Examining a Body of Living Tissues - An illumination apparatus for use in examining a body of living tissues, the apparatus comprising a head for contacting the body of living tissues, a light source mounted in the head for illuminating the tissues, and an annular switch disposed around the light source, the annular switch being adapted automatically to permit illumination of the light source at an examination intensity when the head contacts the body at least around an annular contact area on the head corresponding to the annular switch. | 08-04-2011 |
20110190639 | Bi-Spectral Peroperative Optical Probe - Optical probes for medical applications are provided. The probe is devised so as to be able to be held in one hand. A basic version of the probe includes: a first excitation lighting source suitable for causing a fluorescence radiation of predetermined substances; a second visible lighting source, the first and the second source being devised so as to illuminate a common zone termed the intervention zone; a first photosensitive matrix sensor; and a second photosensitive matrix sensor. The first and second photosensitive matrix sensors are devised in such a way that, when the optical probe is arranged a predetermined distance from the intervention zone, the image in the visible spectrum of the said zone is formed on the photosensitive surface of the first matrix sensor and the image in the fluorescence spectrum of the said zone is formed on the photosensitive surface of the second sensor. A first variant of the probe includes only a single optical objective, a second variant only a single photosensitive matrix sensor, and a third variant makes it possible to work under polarized light. | 08-04-2011 |
20110196239 | Systems, devices, and methods for detection of malaria - Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection. | 08-11-2011 |
20110196240 | IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, IMAGE PROCESSING PROGRAM AND ELECTRONIC APPARATUS - Disclosed herein is an image processing apparatus for extracting a characteristic point from an image, the image processing apparatus including: a first light radiation section; a second light radiation section; an image taking section; a skin-area detection section; and a characteristic-point extraction section. | 08-11-2011 |
20110196241 | DEVICE FOR DIAGNOSIS AND/OR THERAPY OF PHYSIOLOGICAL CHARACTERISTICS OF A SELECTED PORTION OF A BODY BY OPTICAL REFLECTANCE OR OPTICAL TRANSMISSION - The invention relates to a device for diagnosis and/or therapy of a selected portion of a body by optical reflectance or optical transmission. The device according to the invention has a laminar body ( | 08-11-2011 |
20110201939 | METHODS AND SYSTEMS FOR GUIDING AN EMISSION TO A TARGET - Disclosed are methods and systems for guiding emissions to a target. The methods and systems utilize, in part, Markerless Tracking software to detect a beam of energy, such as a laser, toward a target such as a tissue that is the subject of a medical procedure. | 08-18-2011 |
20110201940 | Renal Function Analysis Method and Apparatus - A method for measuring a glomerular filtration rate of a mammalian subject comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the vascular system of the mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the glomerular filtration rate. | 08-18-2011 |
20110201941 | OPTICAL SCANNING PROBE ASSEMBLY - The present invention relates to an optical scanning probe assembly for microscopic guide optic scanning and inspection of tissues suitable for application in, e.g. in vivo medical inspection and biopsy. The assembly comprises an outer housing ( | 08-18-2011 |
20110201942 | DEVICE AND METHOD FOR OPTICALLY EXAMINING THE INTERIOR OF A BODY PART - A device for optically examining the interior of a body part by transillumination is provided. The device comprises: an illumination unit ( | 08-18-2011 |
20110208064 | Curcumin Derivatives for Amyloid-Beta Plaque Imaging - The present invention provides curcumin-derived near infrared (NIR) imaging probes. Upon interacting with amyloid β aggregates, these probes undergo a range of changes, qualifying them as “smart” probes. The inventors have demonstrated that probes of the invention have the capacity to monitor the progression of Alzheimer's disease in an in vivo animal model. In addition, the present invention encompasses probes useful as PET imaging agents, MRI imaging agents and multimodal imaging agents, as well as related methods of detecting and imaging amyloid β aggregates and plaques. | 08-25-2011 |
20110213252 | AUTOFLUORESCENCE IMAGING SYSTEM FOR ENDOSCOPY - A system and method for imaging tissue autofluorescence through a video endoscope is described, comprising a light source capable of providing both ultraviolet light capable of inducing tissue autofluorescence and visible light which induces little or no autofluorescence, an optical system to deliver both wavelength bands to the tissue with the same apparent spatial and angular intensity distribution, a means for digitally acquiring the resulting, visible fluorescence and visible reflectance images using a single imaging detector at the distal tip of the endoscope and a means for digitally processing said images to generate a final, false-color image for display which indicates regions of tissue dysplasia. This system can either be added on to an existing video endoscope or integrated into its structure. The combined system can be electronically switched between normal white light imaging and fluorescence imaging. | 09-01-2011 |
20110237958 | OPTICAL COHERENT CROSS-SECTIONAL IMAGE FORMING APPARATUS AND CONTROL METHOD FOR CONTROLLING SUCH APPARATUS - An optical coherent cross-sectional image forming apparatus in which light outputted from a light source is divided into a measurement light and a reference light inside the apparatus and in which a cross-sectional image is formed based on a coherent light, produced from a reflected light obtained by emitting the measurement light to a biological tissue through a probe inserted into a body lumen, and the reference light, wherein the apparatus includes a detector for detecting that a transmitting and receiving unit entered inside a guiding catheter for guiding the probe by using data during the axial-direction movement and a controller for stopping at least a portion of a process associated with from generation to holding of the cross-sectional image based on the optical coherence in a case in which it is detected by the detector that the transmitting and receiving unit entered inside the guiding catheter. | 09-29-2011 |
20110245683 | OPTICAL IMAGING DIAGNOSTIC APPARATUS AND THE DISPLAY CONTROL METHOD THEREOF - An optical imaging diagnostic apparatus includes a calculation unit for respectively calculating signal-intensity change in the circumferential direction of the circumference of the transmitting and receiving unit and signal-intensity change in the radial direction of a body lumen respectively with respect to a plurality of line data used for generation of a cross-sectional image displayed; a specifying unit for judging, based on the calculated result in the calculation unit, whether or not there exists scatter which scatters the light transmitted from the transmitting and receiving unit in an blood flow area of the body lumen and for specifying the position on the displayed cross-sectional image of the scatter in case of being judged that there exists the scatter; and a display unit for displaying a marker indicating that the scatter exists at the specified position on the displayed cross-sectional image. | 10-06-2011 |
20110245684 | OPTICAL IMAGING DIAGNOSTIC APPARATUS AND THE DISPLAY CONTROL METHOD THEREOF - An optical imaging diagnostic apparatus including: a designating unit for designating a predetermined circumferential-direction position at the circumference of the transmitting and receiving unit on the cross-sectional image displayed; an extraction unit for extracting, within the plurality of line data used for the generation of the cross-sectional image, line data corresponding to circumferential-direction position designated in the designating unit from the storage unit; a calculation unit for calculating attenuation rate in a predetermined region in a radial direction of a body lumen with respect to the extracted line data; and a display unit for displaying the calculated attenuation rate. | 10-06-2011 |
20110245685 | BLOOD VESSEL DISPLAY DEVICE - A blood vessel display device includes: a detection unit that scans body tissue with laser light for detection and detects reflected light from an irradiated part of the body tissue to which the laser light for detection has been irradiated; an image data generating unit that detects a surface shape of the irradiated part and the arrangement of blood vessels, which are present in a superficial layer of the irradiated part, on the basis of a detection result of the detection unit and generates image data of an image for visualizing the blood vessels displayed on the irradiated part; and a display unit that displays an image for visualizing the blood vessels on the irradiated part by scanning the irradiated part with laser light for display on the basis of the image data generated by the image data generating unit. | 10-06-2011 |
20110245686 | OPTICALLY CHARACTERIZING TURBID MEDIA AND SUBSTANCES IN TURBID MEDIA - For optically interrogating substances overlaid by turbid media a method of wavefront manipulation by means of binary phase masking is disclosed. Through altering the degree of mode conformity between the fields reaching the collection optics and the field distributions of the propagation modes of optical waveguides the disclosed method can be used to suppress the collection of short-range light originated near the collection optics while permitting unimpeded collection of light originated from sites substantially behind turbid media. | 10-06-2011 |
20110257533 | BIOLOGICAL INFORMATION MEASUREMENT DEVICE, ILLUMINATION METHOD IN A BIOLOGICAL INFORMATION MEASUREMENT DEVICE, AND BIOLOGICAL INFORMATION MEASUREMENT METHOD - A biological information measurement device that measures biological information of a user includes: a device main body; a fitting-removal section which is provided in the device main body, and to/from which a sensor that measures the biological information is fitted/removed; a light source section that is provided within the device main body at a position spaced apart from the fitting-removal section and that functions as a light source for components of the biological information measurement device other than the fitting-removal section; and a light guide member that guides light emitted by the light source section to a predetermined position in the vicinity of the fitting-removal section to/from which the sensor is fitted/removed. | 10-20-2011 |
20110270092 | COMBINED APPARATUS FOR DETECTION OF MULTISPECTRAL OPTICAL IMAGE EMITTED FROM LIVING BODY AND FOR LIGHT THERAPY - The present invention provides a fluorescence detection and photodynamic therapy apparatus including: a combined light source unit | 11-03-2011 |
20110270093 | OPTICAL EXAMINATION DEVICE ADAPTED TO BE AT LEAST PARTIALLY INSERTED INTO A TURBID MEDIUM - An optical examination device ( | 11-03-2011 |
20110282213 | BIOLOGICAL OBSERVATION APPARATUS - Tumor tissue or the like that exists at a deep portion of a living organism far from an internal wall of a body cavity is observed. A biological observation apparatus ( | 11-17-2011 |
20110282214 | Method for Determining the Condition of a Biological Object and Device for Making Same - The invention relates to the field of instrumentation and can be used for diagnosing the condition of a biological object. The technical result consists in an increased measurement precision. In order to achieve this result, the invention comprises determining the condition of a biological object on the basis of fixation and comparison of the structures of gas-discharge light emission around the reference object and the biological object under study in an electromagnetic field. The light emissions around the reference object and the biological object under study are converted into digital code. The invention comprises determining the quantitative parameters of the light emission and the characteristics thereof. The invention also comprises determining corresponding spatial points of specified parameters for the reference object and the biological object under study. The invention further comprises determining the deviation of quantitative parameters that characterize the condition of the biological object under study by means of the distance between said points. The reference object is implemented as a non-biological material. The invention also comprises carrying out the fixation of the structure of gas-discharge light emission around the reference object and determining the relative deviation thereof from an average value. | 11-17-2011 |
20110295125 | Apparatus and method for radio frequency ablation of a liver tumor in liver tissues - A method for detecting death process of a cell or tissue of a living subject. In one embodiment, the method includes the steps of illuminating the cell or tissue of the living subject with a coherent light, collecting fluorescent light returned from the illuminated cell or tissue of the living subject, identifying a NAD(P)H peak of a spectrum of the collected fluorescent light with a wavelength, λ | 12-01-2011 |
20110306887 | SYSTEM AND METHOD FOR DETERMINING TISSUE CHARACTERISTICS - A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements. The apparatus and system include a base unit having illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. The system and apparatus may also include a tissue interface unit configured to perform spectroscopic measurements on a target tissue, a docking unit configured to support the tissue interface when not in use, the docking unit including an illumination source and a processor that processes spectrographic measurements results received from the tissue interface unit, and a pathway coupling the docking unit and the tissue interface unit. | 12-15-2011 |
20110313295 | Fluorescence Method and System - A method for detecting changes in a human or animal eye is provided. The method includes illuminating the eye or at least a part thereof, in particular the lens and/or cornea, using light at a red edge excitation wavelength; detecting fluorescence caused by the red edge excitation and using the detected fluorescence to detect or identify structural defects or changes in the eye. | 12-22-2011 |
20120004557 | METHOD AND SYSTEM FOR FLUORESCENT IMAGING WITH BACKGROUND SURGICAL IMAGE COMPOSED OF SELECTIVE ILLUMINATION SPECTRA - A surgical site is simultaneously illuminated by less than all the visible color components that make up visible white light, and a fluorescence excitation illumination component by an illuminator in a minimally invasive surgical system. An image capture system acquires an image for each of the visible color components illuminating the surgical site and a fluorescence image, which is excited by the fluorescence excitation component from the illuminator. The minimally invasive surgical system uses the acquired images to generate a background black and white image of the surgical site. The acquired fluorescence image is superimposed on the background black and white image, and is highlighted in a selected color, e.g., green. The background black and white image with the superimposed highlighted fluorescence image is displayed for a user of the system. The highlighted fluorescence image identifies tissue of clinical interest. | 01-05-2012 |
20120010513 | Chemically-selective, label free, microendoscopic system based on coherent anti-stokes raman scattering and microelectromechanical fiber optic probe - An endoscopic microscopic system for collecting and processing a sequence of images. | 01-12-2012 |
20120016245 | PLETHYSMOGRAM SENSOR - The plethysmogram sensor disclosed in this specification includes a light emitting portion whose output is variable, a light receiving portion to detect a light emitted from the light emitting portion and penetrates a living body of a measured person, and a processing unit to acquire information about the plethysmogram of the measured person based on a measured value provided from the light receiving portion. | 01-19-2012 |
20120022380 | METHODS AND APPARATUS FOR ASSESMENT AND TREATMENT OF BODY CAVITIES - Methods and apparatus for detection, assessment and optionally treatment of the cancerous tissue in the natural and manmade body cavities. An expandable cavity assessment device that is coupled with cancer detecting elements is placed in a cavity in close proximity to the site of cancerous tissue. The cavity assessment device may receive an optical fiber, or other type of energy conduit and potentially a radioactive source for interstitial radiation therapy. The cavity assessment device may be equipped with a balloon member coupled with electro conductive elements. Further, a system facilitating substance communication with the internal surface of the cavity is provided. | 01-26-2012 |
20120041315 | Fluorescence Lifetime Spectrometer (FLS) and Methods of Detecting Diseased Tissue - This invention relates to method and apparatus for collection of the complete fluorescence emission spectrum and the transient decay of a selected spectral band simultaneously with data acquisition times of less that one second. This invention is useful for studying human tissues and cells in vivo. | 02-16-2012 |
20120046554 | Fluorescent Fiberoptic Probe for Tissue Health Discrimination and Method of Use Thereof - A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, one of which corresponds to an isosbestic point. In one example, the isosbestic point occurs at about 431 nm. The intensities of the observed signals are normalized using the 431 nm intensity. A score is determined using the ratios in a discriminant analysis. The tissue under examination is resected or not, based on the diagnosis of disease or health, according to the outcome of the discriminant analysis. | 02-23-2012 |
20120046555 | BODY TISSUE IMAGING USING RAMAN SCATTERING LIGHT - An object of the present invention is to provide a method for the noninvasive imaging of a tissue (in particular, a cardiac tissue) in real time, and a device therefor. The present invention provides a method for imaging a sample that contains myocardial tissue and one or more blood vessels and/or one or more collagen-rich regions, the method comprising the steps of: (1) irradiating the sample that contains myocardial tissue and one or more blood vessels and/or one or more collagen-rich regions with an excitation light; (2) detecting Raman scattering light from the sample; and (3) analyzing the thus obtained Raman scattering light by using Raman scattering spectra that are characteristic of myocardial cells and red blood cells and/or collagen as indexes and thus imaging the sample. | 02-23-2012 |
20120059266 | IMAGING METHOD - A docking station for use in combined imaging of a tissue wound and a test substrate comprising a sample from a tissue wound, the docking station comprises means for connecting the station to a processor which processes and stores the images. The docking station also incorporates means for receiving a test substrate comprising a sample from a tissue wound. The docking station also includes means for docking a sensor in the station, which sensor detects the light reflected from an illuminated tissue wound, such that an image of the tissue wound can be communicated from the station to the processor. The means for docking is arranged such that when the sensor is docked in the station and the test substrate is received by the docking station, the sensor is positioned to detect the intensity of reflected light from the test substrate and communicates the detected intensity of reflected light to the processor to thus permit combined imaging of the tissue wound and test substrate. An apparatus for use in combined imaging of a tissue wound and a test substrate comprising a sample from a tissue wound, comprises such a docking station together with a sensor which detects the light reflected from a tissue wound and test substrate when illuminated and a test substrate for receiving a sample from a tissue wound. A method of imaging a wound comprises directing light over a wavelength range of less than 50 nm onto the wound ( | 03-08-2012 |
20120065519 | METHOD AND SYSTEM FOR COLLECTING OPTICAL DATA FOR USE IN TIME RESOLVED OPTICAL IMAGING OF A TURBID MEDIA - There is provided a method and a system for collecting optical data for use in time resolved optical imaging wherein excitation light of a tunable wavelength is directionally propagated to impinge on a plurality of illumination points at the surface of a region of interest in a turbid media, comprising for example a biological tissue such as that comprised in small animals or in human organs. Light re-emitted with a different wavelength from a fluorescent marker present in the tissue is collected and directionally propagated towards a detector. A filter located in a path of the light rejects photons outside a fluorescence emission spectrum of the fluorescent marker while maintaining selectivity of the re-emitted light. The detector produces time resolved optical signals useful for optical image reconstructions. | 03-15-2012 |
20120065520 | OPTICAL MEASUREMENT APPARATUS - An optical measurement apparatus has a light source section, a light receiving section, and a light guiding section. The light source section has a light emitting surface that emits light. The light receiving section has a light receiving surface that receives the light emitted by the emitting surface of the light source to be incident into a body through a surface of the body and which is emitted out of the body after propagating inside the body, the receiving surface facing a direction orthogonal to the emitting surface of the light source, and the receiving section outputting a signal indicative of an amount of the light received by the receiving surface. The light guiding section is provided on a path of the light emitted from the emitting surface and received by the receiving surface to change a traveling direction of the light. | 03-15-2012 |
20120065521 | NEEDLE BIOBSY IMAGING METHOD - Imaging techniques. Radiation is directed from a source onto a sample using an endoscope having cellular or subcellular resolution. The endoscope includes one or more fibers. The fibers have a proximate end and a distal end, and the distal end is lensless. A focal plane of the endoscope is substantially at a tip of the distal end. Radiation from the sample is directed onto a detector to diagnose or monitor the sample. | 03-15-2012 |
20120065522 | Patient Monitoring Apparatus - A patient monitoring system including a sensing-recording device that attaches to a patient and a probe utilized by attending personnel at a trauma site. After an initial interaction between the probe and the sensing-recording device, the sensing-recording device samples one or more physiological parameters and stores time stamped readings in a first memory. The probe is adapted to take other measurements, download the data from the first memory of the sensing-recording device, manipulate the collective data and return data to a second memory in the sensing-recording device. The sensing-recording device continues to accumulate data in the first memory during transport of the patient from a trauma, site to a medical facility. | 03-15-2012 |
20120071764 | DEVICE AND METHOD FOR WIDE-FIELD AND HIGH RESOLUTION IMAGING OF TISSUE - A device for wide-field and high resolution imaging of an object surface includes first and second imaging modalities, a lens associated with the second imaging modality. The first imaging modality is high resolution with a first observation line. The second imaging modality is arranged in an image plane at a first angle with respect to an object plane and has a second observation line and a wider imaging field than the first imaging modality. The lens associated with the second imaging modality is arranged in a lens plane at a second angle with respect to the object plane, where the second angle being equal to about one-half of the first angle. The first and second imaging modalities are mutually arranged such that the first and second optical axes intersect at a point on the object plane. | 03-22-2012 |
20120071765 | Digital Mapping System and Method - Embodiments of the innovation relate to method for generating an image of a tissue element. The method includes generating, by a visualization system controller, a highlighting image representation of the tissue element within a tissue region based upon a first image of the tissue element captured when a first light source illuminates the tissue region, receiving, by the visualization system controller, a second image of the tissue element within the tissue region when a second light source illuminates the tissue region, combining, by the visualization system controller, the highlighting image representation of the tissue element to the second image of the tissue element to generate a composite tissue image, and delivering, by the visualization system controller, the composite tissue image to an output device. | 03-22-2012 |
20120078115 | METHODS TO MEASURE, MAP AND CORRELATE OCULAR MICRO-MOVEMENT AND OCULAR MICRO-TREMOR SIGNALS WITH COGNITIVE PROCESSING CAPABILITIES - An apparatus and method of collecting elements of and assembling various portions of ocular micro motions such as ocular micro-tremor (OMT) movements of the eye, and correlating them directly with OMT waveforms acquired from both known and unknown states of cognition and cognitive function. Comparing newly acquired waveforms from patients with undiagnosed cognitive dysfunctions, permits an individual or caregiver the ability to identify those unknown issues or cognitive states based on matching or relating statistically elements of their waveform with categories of other known cognitive processing normals and abnormals, functional and dysfunctional individuals. It also allows for measuring the effects of therapeutic agents (psychological or pharmacological) by relating them to measurable changes in cognitive function as a result of correlated changes in waveforms. | 03-29-2012 |
20120078116 | BIOLOGICAL INFORMATION DETECTOR AND BIOLOGICAL INFORMATION MEASURING DEVICE - A biological information detector includes a light-emitting part for emitting light in an emission wavelength band that includes a wavelength of interest, a light-receiving part for receiving light R | 03-29-2012 |
20120078117 | BLOOD VESSEL INNER WALL ANALYZING DEVICE AND BLOOD VESSEL INNER WALL ANALYZING METHOD - The present invention relates to a blood vessel inner wall analyzing apparatus provided with a structure for more accurately analyzing components of substances adhered to the inner walls of blood vessels. A blood vessel inner wall analyzing apparatus ( | 03-29-2012 |
20120089030 | SYSTEM AND METHOD FOR CHARACTERIZATION OF ORAL, SYSTEMIC AND MUCOSAL TISSUE UTILIZING RAMAN SPECTROSCOPY - A method and system for characterizing tissue includes a probe connected to a red LASER source and a Raman spectroscope. The probe includes at least excitation fiber and one or more emission fibers that connect the probe with the LASER source and the Raman spectroscope. The excitation fiber is connected to the red LASER source and terminates in the first end of the probe adjacent the tip of the probe. The emission fibers are connected to the Raman spectroscope and terminate in the first end of the probe adjacent the tip of the probe. In one embodiment, the excitation fiber extends through the central portion of the probe and one or more emission fibers are arranged around the excitation fiber. The tip of the probe is intended to come in contact with the tissue to be examined. The tip includes a central opening to allow red LASER radiation to project out of the end of the red excitation fiber on to the tissue and to permit Raman spectra to enter the emission fiber(s) and travel to the Raman spectroscope. The tip is constructed to have a predefined focal length to position the first end of the probe a predefined distance from the surface of the tissue being examined. The tip can be removable and tips having different focal lengths can be used to accommodate different types of tissues and examinations. A detector can convert the Raman spectra into signals and data for analysis by a computer system. The Raman spectra for tissue in a predefined location can be profiled such that the system can distinguish between healthy and diseased tissue. | 04-12-2012 |
20120089031 | SYSTEMS AND METHODS FOR SIDESSTREAM DARK FIELD IMAGING - The present application discloses systems and methods for the comprehensive monitoring of the microcirculation in order to assess the ultimate efficacy of the cardiovascular system in delivering adequate amounts of oxygen to the organ cells. In some cases, system embodiments may utilize reflectance avoidance by reflectance filtering, such as OPS imaging or Mainstream Dark Field imaging, or by Sidestream Dark Field imaging, which utilizes external direct light on the tip of the light guide to achieve reflectance avoidance whereby incident and reflected light do not travel down the same pathway. | 04-12-2012 |
20120101390 | Multi-Modal Imaging for Diagnosis of Early Stage Epithelial Cancers - Epithelial cancer screening can include a staining tissue with a cancer targeting agent, identifying a potentially cancerous lesion using fluorescence imaging, and imaging the potentially cancerous lesion for a cancer diagnosis using optical coherence tomography. | 04-26-2012 |
20120101391 | BLOOD VESSEL WALL ANALYZING DEVICE AND BLOOD VESSEL WALL ANALYZING METHOD - The present invention relates to a blood vessel wall analyzing apparatus provided with a structure enabling accurate measurement of plaque components in a blood vessel wall in a state that reduces the burden on a patient. In the blood vessel wall analyzing apparatus ( | 04-26-2012 |
20120108981 | APPARATUS AND METHOD FOR SPECTROPHOTOMETRIC MEASUREMENTS OF BLOOD PARAMETERS - An apparatus for measuring the blood parameters in an extracorporeal circuit comprises: a seat ( | 05-03-2012 |
20120108982 | SYSTEMS AND METHODS FOR IN-VIVO OPTICAL IMAGING AND MEASUREMENT - Disclosed are methods and systems for: (i) sequentially illuminating a specimen with different spatial distributions of light, wherein each illumination causes an object embedded in the specimen to emit radiation in response to the light; (ii) for each different spatial distribution of illumination light, imaging the radiation emitted from the specimen from each of multiple sides of the specimen; and (iii) determining information about the object in the specimen based on the imaged radiation from each of the multiple sides for each of the different spatial distributions of illumination light. | 05-03-2012 |
20120116232 | METHOD FOR DETERMINATION OF UNKNOWN MUTATIONS - The present invention relates to a method of using Raman spectra to identify unknown mutations in a gene, more specifically the filaggrin gene. Specifically, the present invention relates to a method to determine if a person has a homozygous or compound heterozygous mutation in the filaggrin-gene comprising measurement of the presence of tyrosine in the skin. Preferably said measurements are performed by Rama spectrography and on the tsiie of the skin, most preferably on the palm of the hand. Further, when these measurements are taken together with measurements of the NMF content of the skin it, the present invention relates to a method of classifying atopic dermatitis. | 05-10-2012 |
20120116233 | SENSOR SYSTEM - A sensor system adapted for characterizing a region of interest within a subject while minimizing bleeding is provided. The sensor system comprises a hollow tool configured to be inserted into the subject, the hollow tool comprising an orifice positioned at an angle with respect to its horizontal axis, a probe disposed within the hollow tool and configured to transmit data from the region of interest; wherein the probe protrudes from the orifice of the hollow tool to be in contact with the region of interest and processing circuitry coupled to the probe and configured to process the sensed data to characterize the region of interest. | 05-10-2012 |
20120123276 | CATHETER WITH OPTICAL CONTACT SENSING - A medical probe, including a biocompatible sheath having proximal and distal ends, and having at least one transparent strip between the proximal end and the distal end. The probe also has one or more functional elements positioned within the biocompatible sheath. | 05-17-2012 |
20120123277 | METHOD FOR DETECTING AN EXTRAORDINARY SITUATION - A method for detecting an abnormal situation of a person, a contact measuring device which the person wears directly or indirectly on the body and which is a contact sensor and/or a pressure sensor and/or a photosensor and/or a distance measuring device being used to determine a contact state and/or the pressure exerted by a body part, such as a foot of a person, onto a reference surface, such as a floor, so that an abnormal situation can be detected among a plurality of situations. | 05-17-2012 |
20120123278 | LOW-NOISE OPTICAL PROBES FOR REDUCING AMBIENT NOISE - An optical probe, which is particularly suited to reduce noise in measurements taken on an easily compressible material, such as a finger, a toe, a forehead, an earlobe, or a lip, measures characteristics of the material. A neonatal and adult disposable embodiment of the probe include adhesive coated surfaces to securely affix the probe onto the patient. In addition, the surface of the probe is specially constructed to reduce the effect of ambient noise. | 05-17-2012 |
20120130252 | PRODUCING AN IMAGE - An optical component is connectable to a camera unit and comprises a data structure including data associated with the optical component. When the optical component is connected to the camera unit, data associated with the optical component is transferred to the camera unit. Image production of an organ by the camera unit is controlled based on the data associated with the optical component. | 05-24-2012 |
20120130253 | NON-CONTACT OPTICAL SYSTEM, COMPUTER-ACCESSIBLE MEDIUM AND METHOD FOR MEASUREMENT AT LEAST ONE MECHANICAL PROPERTY OF TISSUE USING COHERENT SPECKLE TECHNIQUE(S) - Exemplary embodiments of apparatus and method for determining at least one material property of an anatomical structure can be provided. According to one exemplary embodiment, it is possible to apply at least one first coherent radiation to at least one portion of the anatomical structure, and receive at least one second coherent radiation from such portion(s). The first and second coherent radiations can be associated with one another. In addition, it is possible to determine the material property based on the second coherent radiation(s). Such determination can be performed without (i) any portion of an apparatus performing the procedure causing an induction of at least one mechanical deformation on or in the anatomical structure, and/or (ii) any mechanical deformation on or in the anatomical structure. | 05-24-2012 |
20120130254 | Dental Device for Trans-illumination of Teeth - In a dental system for the transillumination of teeth having an elongate handpiece with a light source for producing examination radiation, irradiation means for directing the examination radiation at a tooth to be examined, and means for acquiring an optical image of the tooth illuminated by the examination radiation, there is arranged at the front end of the handpiece a removable attachment which contains at least part of the irradiation means, the handpiece having means for detecting the attachment arranged on the handpiece. | 05-24-2012 |
20120130255 | MEDICAL DEVICE FOR DIAGNOSING PRESSURE ULCERS - Medical device or instrument for diagnosing pressure ulcers using optical reflectance spectroscopy. The device may comprise a tip and a controller. The tip is pressed against the skin of the patient and collects the optical reflectance data. The controller processes the data to determine whether there exists a pressure ulcer and, if there is one, its depth. The tip may also include a pressure sensor for sensing the pressure at which the tip is applied to the patient's skin. | 05-24-2012 |
20120130256 | Method and System for Controlling Output of RF Medical Generator - A control system for controlling the output of an electrosurgical generator is disclosed. The control system includes a control module configured to receive an optical signal from a surgical site, the optical signal being related to an optical tissue characteristic, the control module configured to process the optical signal using a closed loop control loop and provide continual control of the output of the electrosurgical generator in response to the optical tissue characteristic. | 05-24-2012 |
20120130257 | METHOD AND APPARATUS FOR TISSUE MEASUREMENT POSITION TRACKING AND DEPTH ADJUSTMENT - The present invention pertains to a method and apparatus for pressure sore detection. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is derived from the modulated optical signal. Tissue characteristics is determined based on the temporal transfer characteristic. | 05-24-2012 |
20120130258 | PROGRAMMABLE MULTIPSPECTRAL ILLIUMINATION SYSTEM FOR SURGERY AND VISUALIZATION OF LIGHT-SENSITIVE TISSUES - An observation system for viewing light-sensitive tissue includes an illumination system configured to illuminate the light-sensitive tissue, an imaging system configured to image at least a portion of the light-sensitive tissue upon being illuminated by the illumination system, and an image display system in communication with the imaging system to display an image of the portion of the light-sensitive tissue. The illumination system is configured to illuminate the light-sensitive tissue with a reduced amount of light within a preselected wavelength range compared to multispectral illumination light, and the image of the portion of the light-sensitive tissue is compensated for the reduced amount of light within the preselected frequency range to approximate an image of the light-sensitive tissue under the multispectral illumination | 05-24-2012 |
20120136257 | SNR Through Ambient Light Cancellation - Systems, methods, and devices for improved patient monitor signal processing with higher signal-to-noise ratio (SNR) are provided. In accordance with an embodiment, an electronic patient monitor may include drive circuitry, a current-to-voltage converter, and feedback circuitry. The drive circuitry may drive an emitter of a medical sensor with dark periods during which the emitter does not emit light, and the current-to-voltage converter may receive and amplify a photocurrent signal from a detector of the sensor. The feedback circuitry may provide a feedback signal to the current-to-voltage converter. The feedback signal, based at least in part on the output of the current-to-voltage converter during the dark periods, may cause the current-to-voltage converter to substantially exclude an ambient light component of the photocurrent. As a result, the current-to-voltage converter may employ a higher transimpedance without distorting the output voltage signal due to oversaturation, and thus may achieve a higher SNR. | 05-31-2012 |
20120136258 | Retinal Flow Cytometry - The present invention provides methods and devices for performing flow cytometry. In one embodiment, blood circulating through one or more retinal blood vessels of a subject is illuminated in-vivo so as to excite a plurality of fluorescent-labeled cells contained in the blood. The fluorescence radiation emitted by the excited cells is then detected and analyzed to count the cells from which fluorescence is detected. | 05-31-2012 |
20120143064 | MUSCLE FUNCTION EVALUATING SYSTEM - A muscular function monitoring and evaluating system includes a processor, a wireless interface, a display, a storage device storing a program and sets of test procedures, a signal collection device wirelessly coupled to the processor and a sensor connected to the signal collection device. The program, when executed by the processor, causes the system to display a patient information screen on the display for an operator to input patient's data of a patient to be tested, and receive the patient's data input through the screen. The processor displays, in accordance with one of the sets of test procedures, a muscle map indicating a place on the patient's body to which the sensor is to be attached. The processor instructs the patient through displayed instruction language, an animation or video image, or audible instructions. | 06-07-2012 |
20120150042 | VACUUM-PUMP SUCKER - This invention relates to a vacuum-pump sucker for high-resolution microscopy comprising a sucker body and a transparent plate. The vacuum-pump sucker is designed as a stabilizer for sample stabilization in a clinical optical virtual biopsy system with sub-micron resolution. The sucker is connected with a vacuum pump. As the vacuum pump pumps out air or gas, tissues around the imaged area will be sucked by the sucker and the distance between objective lens and the imaged tissue can be stabilized. In this way, the stability and resolution of the clinical biopsy system can be greatly improved. | 06-14-2012 |
20120150043 | SYSTEMS AND METHODS FOR GENERATING FLUORESCENT LIGHT IMAGES - An imaging system divides image pixels intensities by exposure time to generate image data in units of intensity per time. The imaging system divides a fluorescent light image in intensity per time units by an excitation light image in intensity per time units to provide a quantitative corrected fluorescent light image that is generally invariant to position of an imaging instrument relative to a biological tissue being imaged. | 06-14-2012 |
20120150044 | PHOTOTHERAPY DEVICE AND METHOD - Disclosed is a phototherapy device including: a pixel unit to irradiate light having a predetermined wavelength to a skin, detect a skin reflection light of the light irradiated to the skin, and convert the detected skin reflection light into an electrical signal; an image processor to use the electrical signals to generate skin image information; and a control unit to control light intensity irradiated to the skin for a skin diagnosis or a skin disease therapy based on the skin image information, or to determine a two-dimensional distribution of the light. The phototherapy device of the present disclosure simultaneously provides the diagnosis and therapy of the skin disease. | 06-14-2012 |
20120150045 | ENDOSCOPE SYSTEM FOR FLUORESCENT OBSERVATION - An endoscope system is disclosed for detecting fluorescent light emitted in the near-infrared region by a plurality of fluorescent labeling materials introduced into a living tissue. An illumination system generates illumination light in the wavelength range 600 nm-2000 nm which serves as excitation light for the plurality of fluorescent labeling materials, and a detection system that can separately detect different ones of the plurality of fluorescent light emissions that are emitted at different wavelengths from among the plurality of fluorescent labeling materials is provided. The endoscope system may include a conventional-type endoscope having an insertion section, or a capsule endoscope that wirelessly transmits image data. By superimposing the image data obtained using reflected light in the visible region and fluorescent light emitted by the fluorescent labeling materials, improved diagnostic capabilities are provided. | 06-14-2012 |
20120165681 | Delineating Skin or Surface Lesions - A diagnostic apparatus for examining a region of skin includes a light source for emitting light toward an illumination region of the skin surface. A detector is provided for receiving light from an examination region of the skin surface. A light barrier substantially impervious to the light emitted from the light source intimately engages the skin surface to define a boundary between the illumination region and the examination region. | 06-28-2012 |
20120165682 | SKIN COLOR AND CAPACITIVE SENSOR SYSTEMS - A hair removal device utilizes a system for sensing the presence and color of skin. The system includes a skin color sensor assembly and a capacitive sensor assembly disposed in a housing. The skin color sensor assembly includes a light pipe communicating with a color sensor aperture of the housing and having one or more notches defining receiving and emitting light propagation regions, a color sensor and one or more light emitting diodes, and a holder having at least one standoff mated to the notches thereby directing light emitted by the light emitting diodes through the light pipe for reflection of an external surface and receipt by the sensor for detection of surface color. The capacitive sensor assembly includes a plurality of copper elements in proximity to a device aperture and contacting an interior surface of the housing and for detection of an object in contact with the copper elements. | 06-28-2012 |
20120165683 | PERSONAL IDENTIFICATION SYSTEM - A personal identification system, which uses a vein pattern of a finger, optimizes the amount of light of a light source based on a captured finger image and emphasizes the vein pattern during image processing for identification. | 06-28-2012 |
20120179050 | ENDOSCOPE DIAGNOSIS SYSTEM - An endoscopic diagnosis system includes a white light source, a narrowband light source for emitting narrowband light having a given wavelength range of blue light, an image sensor receiving reflected light of white light and the narrowband light emitted with a given emission ratio to illuminate a subject from the subject to acquire a narrowband light image, and an image processor for calculating an enhanced luminance signal where a blue image signal of the narrowband light image is enhanced, calculating a hemoglobin index representing blood level in a medium to deep layer of a mucous membrane from a green image signal and a red image signal of the narrowband light image, calculating an enhanced color difference signal enhancing red according to a value of the hemoglobin index, and producing an image signal of an endoscopic image for display. | 07-12-2012 |
20120184857 | OPHTHALMIC LASER TREATMENT APPARATUS - An ophthalmic laser treatment apparatus comprises: a main unit; a laser source; a hand-held cabinet; a laser delivery optical system for irradiating the laser beam in a predetermined irradiation pattern onto tissues of the patient's eye, the laser delivery optical system including: a fiber unit connecting the hand-held cabinet to the main unit; a scanner for deflecting an optical axis of the laser beam; and an image forming optical system for forming an image of the laser beam in the form of a spot on the tissues of the patient's eye; an irradiation pattern setting unit for setting an irradiation pattern of the treatment laser beam; a control unit for controlling drive of the scanner; and a beam combiner provided in the hand-held cabinet to make an observation optical path and an optical path of the laser delivery optical system coincident with each other. | 07-19-2012 |
20120190989 | DISTRIBUTED EXTERNAL AND INTERNAL WIRELESS SENSOR SYSTEMS FOR CHARACTERIZATION OF SURFACE AND SUBSURFACE BIOMEDICAL STRUCTURE AND CONDITION - Systems and methods are disclosed that use wireless coupling of energy for operation of both external and internal devices, including external sensor arrays and implantable devices. The signals conveyed may be electronic, optical, acoustic, biomechanical, and others to provide in situ sensing and monitoring of internal anatomies and implants using a wireless, biocompatible electromagnetic powered sensor systems. | 07-26-2012 |
20120197133 | Advanced Ultrasound Modulated Optical Spectroscopy And Its Application To Patient Monitoring - The present disclosure describes systems and methods that use spatial modulation to focus light into a localized region of interest such as an individual blood vessel. In certain embodiments, acoustic modulation techniques, such as ultrasound pulse modulation, are used in conjunction with spatial modulation to achieve more precise measurements through otherwise scattering medium. The focused beam of light is capable of penetrating several centimeters of tissue to deliver measurements and images associated with individual blood vessels and other discrete vascular components. | 08-02-2012 |
20120197134 | Lesion Extracting Device and Lesion Extracting Method - A lesion extracting device includes a light source for emitting an excitation light toward a subject body, a control unit for changing an amount of the excitation light, a light irradiating and receiving portion for irradiating the excitation light to the subject body and receiving fluorescence generated from the subject body, a distance holding member for holding a distance between the subject body and the light irradiating and receiving portion at a predetermined value, a measuring unit for measuring the intensity of the fluorescence received by the light irradiating and receiving portion, and an extracting unit for extracting a lesion part of the subject body based on relationships between measured values of changes in the fluorescence intensity with respect to changes in the amount of the excitation light and information regarding the changes in the amount of the excitation light, the information being obtained from the control unit. | 08-02-2012 |
20120197135 | DEVICE FOR INTERMITTENTLY PERFORMING CARE SESSIONS TO FORM A LARGE SKIN AREA CARE - A device of guiding a multiple area dermatologic care process. The device comprises a carrier which supports a drive of a dermatologic care tool over a skin area while the dermatologic care tool intermittently performs a plurality of dermatologic care sessions each in one of a plurality of skin subareas of the skin area and a brake unit which regulates a movement of the carrier from a first skin subarea to a second skin subarea during the drive of the dermatologic care tool. | 08-02-2012 |
20120203114 | INTRINSIC AND SWEPT-SOURCE RAMAN SPECTROSCOPY - The present invention pertains to a method and an apparatus for Raman spectroscopy of human tissue. Human tissue is illuminated with a laser emitting a first wavelength of light. A Raman signal is measured and optical properties are determined at this wavelength such that the measured Raman signal can be corrected based on determined optical properties. Determined optical properties may be the scattering coefficient and absorption coefficient of the tissue. A system for Raman spectroscopy of human tissue includes a frequency sweeping laser light source for illumination, and a filtered detector for collecting the Raman signal. | 08-09-2012 |
20120203115 | SYSTEM AND METHOD FOR NONINVASIVE TISSUE EXAMINATION - A processing utility analyzes first measured data including at least two measured data pieces from at least two first spaced-apart measurement locations respectively within a first sub-region of the region of interest, and determines for each of the first locations a deviation parameter corresponding to deviation of the measured data piece from the reference response. The processing utility determines, for each of said at least two of the measured data pieces of the first measured data, a relation between the deviation parameter and a predetermined threshold value corresponding to a condition of said predetermined abnormality, and generate a corresponding control signal and communicate it to the measurement unit. The control signal is indicative of a first scan direction towards at least one second location to be measured in the region of interest where a degree of said predetermined abnormality is higher than in said at least two first locations. | 08-09-2012 |
20120209123 | Surgeon's Aid for Medical Display - A system for identifying an area of interest on a surgical image, including a source of surgical image data, which may be a camera, an image processing unit, which may be a camera control unit, and a destination, which may be a display. The image processing unit is configured to receive the surgical image data and combine it with an overlay pattern for identifying an area of interest, which is then displayed on the display. The overlay may include a key with coordinates or labels. Properties of the overlay and the key may be customized and adjusted. | 08-16-2012 |
20120209124 | BREAST HEALTH CARE DEVICE - The present invention relates to a breast health care device, which comprises: a main body, which comprises at least one cover portion; and at least one node module, which is disposed on the cover portion. The node module comprises a light-emitting unit, a photo detector, or the combination thereof, wherein the light-emitting unit provides a light of predetermined wavelength to a breast tissue, and the photo detector detects a first signal generated from the breast tissue. Thus, users can directly achieve detection for the health condition of breasts by wearing the bra of the disclosed breast health care device of the present invention, and the disclosed health care device can transmit the detection results to an external health-care platform such as hospitals or medical centers immediately. | 08-16-2012 |
20120209125 | Singlet Oxygen Production and Dosimetry for Photodynamic Therapy - An apparatus for photodynamic therapy (PDT) includes a light source configured to provide excitation light for a photosensitizer, an optical system configured to direct the excitation light to a target region and receive light emitted by the photosensitizer and/or singlet oxygen generated in the target region, and a detection system configured to receive the light emitted by the photosensitizer and/or the singlet oxygen. The apparatus also includes a filter system configured to spectrally discriminate between emission from the photosensitizer and the singlet oxygen and a processor configured to determine concentrations of the singlet oxygen and/or the photosensitizer based on an emission signal measured by the detection system. | 08-16-2012 |
20120220878 | Blanching Device for Use in Evaluating Skin Condition - A blanching device is described for use in evaluating skin condition. The blanching device has a window which is pressed against the skin, and retracts when a pre-determined pressure is reached to allow blood to re-enter the blanched region of skin. There is further described systems to evaluate skin condition using a blanching device, based on light scattered from the blanched region. | 08-30-2012 |
20120226166 | DELIVERY OF BIOLOGICAL COMPOUNDS TO ISCHEMIC AND/OR INFARCTED TISSUE - The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue. | 09-06-2012 |
20120232404 | Method And Apparatus For Rapid Detection And Diagnosis Of Tissue Abnormalities - A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics and correlate same to photographic images. Further, the system and method accomplish this measurement rapidly by increasing the light throughput by integrating optics into a hand held unit and avoiding the need for a coherent fiber optic bundle being used. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements. | 09-13-2012 |
20120232405 | COMPACT PROBE FOR TRACER-ASSISTED DIAGNOSTIC AND SURGERY - A simple and potentially disposable compact probe of FIG. | 09-13-2012 |
20120232406 | Oral screening device - An oral cancer screening device | 09-13-2012 |
20120238881 | ORAL OPTICAL DIAGNOSING APPARATUS AND OPERATING METHOD THEREOF - An oral optical diagnosing apparatus and operating method are disclosed. The oral optical diagnosing apparatus includes a positioning module, an optical sensing module, a processing module, and a display module. After the positioning module selects a region to be diagnosed in a mouth, the optical sensing module will perform optical sensing on the region to be diagnosed to obtain optical information related to the region to be diagnosed. The processing module is used to analyze the optical information to generate an optical diagnosed result. The display module is used to display the optical diagnosed result. | 09-20-2012 |
20120238882 | SKIN OPTICAL DIAGNOSING APPARATUS AND OPERATING METHOD THEREOF - A skin optical diagnosing apparatus and operating method thereof are disclosed. The skin optical diagnosing apparatus includes a positioning module, an optical sensing module, a processing module, and a display module. The skin optical diagnosing apparatus uses the positioning module to select a target region on a sample, and then the optical sensing module performs an optical sensing on the target region to obtain an optical information data related to the target region. The processing module is used for processing the optical information data to generate an optical diagnosed result. The display module is used for displaying the optical diagnosed result. | 09-20-2012 |
20120238883 | OPTICAL MEASUREMENT SYSTEM, PORTABLE OPTICAL MEASUREMENT DEVICE USED THEREIN, AND REHABILITATION PLANNING METHOD USING SAME - An optical measurement system having a main and a portable optical measurement devices. The portable optical measurement device is provided with a second case portable by the subject, C second light sending means for illuminating the subject, D second light receiving means receiving light emitted from the subject, a second holder worn on the head of the subject and having at least (C+D) through holes therein, a control unit acquiring measurement data relating to a brain activity while controlling the second light sending and receiving means, and a communication unit communicating with the main optical measurement device, that (C+D)>(A+B) is satisfied, and that the communication unit of the portable optical measurement device transmits the measurement data acquired by the control unit of the portable optical measurement device to the main optical measurement device. | 09-20-2012 |
20120253202 | Optoelectronic Device for The Detection of Uterine Cervical Cancer, Comprising A Self-Positioning Attachment - The disclosure is directed to a minimally-invasive diagnostic device for Papanicolaou testing and for an alternative examination method for taking a cell sample. The portable device analyzes cervical tissue using simultaneous electrical and optical measurements. The device examines different areas of cervical tissue, taking electrical measurements in different frequency ranges and optical measurements in three different wavelengths. Once obtained, the measurements are processed in accordance with mathematical formulae obtained from multiple measurements of healthy and cancerous tissues. Three possible responses can be obtained: healthy tissue, cancerous tissue, or the presence of human papilloma virus. A device attachment permits use of the device for self-detection after determining proximity to the cervix, and also includes an accessory for performing the alternative method of taking a cell sample for laboratory analysis to obtain an immediate response for use by the user or another person. | 10-04-2012 |
20120253203 | METHOD OF VIEWING A SURFACE - A method of viewing a surface comprising taking at least a first image from a first position and a second image from a second position to allow for comparative analysis and diagnosis of the surface. | 10-04-2012 |
20120253204 | SYSTEMS AND METHODS FOR PHOTOTHERAPEUTIC TREATMENT OF RECTAL DISEASES - A phototherapeutic system for providing phototherapy to a patient's lower parts of a gastrointestinal (GI) tract, the phototherapeutic system including a capsule sized and shaped for insertion into the rectum, the capsule including one or more phototherapeutic light sources. A method for intra-luminal phototherapy of the lower parts of the gastrointestinal (GI) tract including inserting a phototherapeutic device including one or more phototherapeutic light sources into the rectum, activating the light sources, and providing light at a dose suitable for providing a phototherapeutic effect. Related apparatus and methods are also described. | 10-04-2012 |
20120259228 | TRI MODAL SPECTROSCOPIC IMAGING - The present invention relates to a spectroscopic imaging system using autofluorescence and reflectance images to diagnose tissue. A preferred embodiment of the invention uses a plurality of light sources to illuminate a tissue region to provide the fluorescence and reflectance images, respectively. | 10-11-2012 |
20120259229 | APPARATUS AND METHODS FOR IN VIVO TISSUE CHARACTERIZATION BY RAMAN SPECTROSCOPY - A micro-Raman spectrometer system for use in differentiating tumor lesions from normal skin detects specific characteristics of Raman spectra indicative of cancer. A peak at 899 cm | 10-11-2012 |
20120271176 | METHOD AND SYSTEM FOR OPTICALLY EVALUATING PROXIMITY TO THE INFERIOR ALVEOLAR NERVE IN SITU - A low coherence interferometry probe system for evaluating proximity to a tissue layer, comprising a low coherence light source, an excitation optical fiber to bring the low coherence excitation light near the tissue layer and a collection optical fiber for capturing back-scattered light from the tissue layer. The probe system comprises an interferometry sub-system and a processor for evaluating a distance to the tissue layer. There is also provided a spectral absorption probe system for evaluating proximity to an artery, comprising a light source excitation light having a wavelength adapted for absorption by blood chromophores, an excitation optical fiber and a collection optical fiber. The probe system comprises a light detector and a processor for determining a distance to the artery using the Beer-Lambert law of light absorption with a value for surrounding tissue attenuation coefficient (μeff). A probe system combining low coherence interferometry and spectral absorption is also provided. | 10-25-2012 |
20120277593 | IMAGING BASED INTERFEROMETRIC PRESSURE SENSOR - An imaging based interferometric pressure sensor apparatus compromise a fluid pressure sensor unit ( | 11-01-2012 |
20120277594 | MENTAL HEALTH AND WELL-BEING - Mental illness is a huge burden on those afflicted with it, as well as their caregivers and represents a major cost to society as a whole. The invention herein is concerned with methods and apparatus to improve the well-being of persons afflicted with mental illness, as well as to provide early and better diagnosis. It is felt that in some cases such diagnosis can lead to a potential for eliminating the worst effects of the illness altogether, by allowing intervention before a first psychotic episode occurs. The invention uses sensors, primarily 2D or 3D cameras and voice recognition to observe persons in many instances during ordinary activity such as playing video games, chatting on the internet or other such computer based activity. | 11-01-2012 |
20120283573 | DETECTION DEVICE FOR CHINESE MEDICAL INSPECTION DIAGNOSIS - The present invention is to provide a monitoring device for inspection diagnosis in traditional Chinese medicine, comprising: a housing, a light source and a shooting structure, the said light source and shooting structure are positioned in the housing, a photoconductive component is positioned in the said housing, the said photoconductive component comprising at least one photoconductive layer, the said light source is positioned inside the photoconductive layer or on the side cross section of the photoconductive layer, with the diffuse reflection of the photoconductive component the said light source forms a area light source. In the present invention, as the photoconductive component is adopted in light transmission, the point light is converted to area light so that a soft, stable and uniform illumination environment similar to the natural light comes into being in the monitoring device. | 11-08-2012 |
20120283574 | Diagnosis Support System Providing Guidance to a User by Automated Retrieval of Similar Cancer Images with User Feedback - The present invention is a diagnosis support system providing automated guidance to a user by automated retrieval of similar disease images and user feedback. High resolution standardized labeled and unlabeled, annotated and non-annotated images of diseased tissue in a database are clustered, preferably with expert feedback. An image retrieval application automatically computes image signatures for a query image and a representative image from each cluster, by segmenting the images into regions and extracting image features in the regions to produce feature vectors, and then comparing the feature vectors using a similarity measure. Preferably the features of the image signatures are extended beyond shape, color and texture of regions, by features specific to the disease. Optionally, the most discriminative features are used in creating the image signatures. A list of the most similar images is returned in response to a query. Keyword query is also supported. | 11-08-2012 |
20120283575 | REMOTE NON-INVASIVE PARAMETER SENSING SYSTEM AND METHOD - A remote parameter sensing system is provide that includes a gel sensor, a light source, a detector and a controller | 11-08-2012 |
20120296217 | METHOD AND APPARATUS FOR DELIVERING AN ENDOSCOPE VIA MICROSURGICAL INSTRUMENTS WHILE PERFORMING MICROSCOPIC SURGERY - The present invention relates to a surgical apparatus that includes a surgical instrument including an elongated shaft extending along a longitudinal axis from a proximal end to a distal end, a working element coupled to the distal end of the elongated shaft for manipulating tissue; an endoscope having a tubular body including an image fiber, an endoscopic lens coupled to a distal end of the tubular body and operably coupled to the image fiber, the endoscopic lens defining a viewing field about a central axis; and the endoscope mounted to the elongated shaft of the surgical instrument, the endoscopic lens protruding from an outer longitudinal surface of the elongated shaft, the central axis of the viewing field being oblique to the longitudinal axis of the elongated shaft and intersecting the outer longitudinal surface, the working element located within the viewing field and separated from the central axis by a distance. | 11-22-2012 |
20120302892 | PORTABLE OPTICAL FIBER PROBE-BASED SPECTROSCOPIC SCANNER FOR RAPID CANCER DIAGNOSIS - A multimodal probe system for spectroscopic scanning of tissue for disease diagnosis. The system can use diffuse reflectance spectroscopy, fluorescence spectroscopy and Raman spectroscopy for the detection of cancerous tissue, such as tissue margin assessment. | 11-29-2012 |
20120310097 | SURGICAL IMAGING DEVICE - A surgical imaging device includes at least one light source for illuminating an object, at least two image sensors configured to generate image data corresponding to the object in the form of an image frame, and a video processor configured to receive from each image sensor the image data corresponding to the image frames and to process the image data so as to generate a composite image. The video processor may be configured to normalize, stabilize, orient and/or stitch the image data received from each image sensor so as to generate the composite image. Preferably, the video processor stitches the image data received from each image sensor by processing a portion of image data received from one image sensor that overlaps with a portion of image data received from another image sensor. | 12-06-2012 |
20120310098 | LASER ENHANCED RECONSTRUCTION OF 3D SURFACE - A method for reconstructing a surface of a three-dimensional object ( | 12-06-2012 |
20120316446 | RAMAN SPECTRAL ANALYSIS FOR DISEASE DETECTION AND MONITORING - A system and method for Raman spectral analysis for diagnostic purposes to identify the disease state of biological tissue. The sampled tissue can be any human or animal tissue, including but not limited to prostate, breast, cervical tissue, etc. Raman spectroscopy is used to provide Raman bands which are decomposed and their chemical fingerprints identified after mathematical modeling. The method enables identification of chemical compounds in the tissue being diagnosed. Comparison with reference samples permits inferences concerning the presence or absence of disease, the stage of disease, and/or the response of disease to treatment. The method provides sufficient information about the chemical composition of the tissue to differentiate between normal and abnormal states, and may also reveal the locations of abnormalities. The method may also be used to monitor the treatment of a subject and/or the response of disease to drugs or other treatments. | 12-13-2012 |
20120330161 | CO2 SENSOR AND CO2 MEASURING APPARATUS | 12-27-2012 |
20120330162 | MODULATED APERTURE IMAGING FOR AUTOMATIC MOVING TARGET DETECTION - Traditional methods of detecting a moving target involve acquisition of video rate imagery in which data is acquired, stored, transmitted and then processed. Processing requires software for high precision frame-to-frame registration, detection and tracking. Example embodiments of the present invention include a method and an apparatus for generating instantaneous velocity maps that do not require acquisition, transmission, storing or processing of video-rate data. Incident radiation is directed onto one or more detectors, the detectors operating at a frame rate. The detectors acquire the first and second complementary sub-images of a single frame. The first and second complementary sub-images are combined to yield the change detection map. Example embodiments of the methods and devices described herein can be used in automatic detection of motion without tracking, optimization of image deblurring and optimization of detection of high speed and high frequency events, among others. | 12-27-2012 |
20120330163 | MEASURING APPARATUS - The present invention provides a measuring apparatus including: a supporting member which supports a subject person and has an opening for inserting an object that is a part of the subject person; and a first holding member and a second holding member for interposing and compressing the object when the object is inserted through the opening, wherein at least two of the supporting member, the first holding member and the second holding member can move independently from one another in a direction of compressing the object. | 12-27-2012 |
20120330164 | NONINVASIVE MEASUREMENT OF CAROTENOIDS IN BIOLOGICAL TISSUE - A method and apparatus are provided for the determination of carotenoid antioxidants and similar chemical compounds in biological tissue such as living skin. The method and apparatus provide a noninvasive, rapid, accurate, and safe determination of carotenoid levels which in turn can provide diagnostic information of the antioxidant status of tissue. Reflection spectroscopy is used to measure the concentrations of carotenoids and similar substances in tissue. White light is directed upon the area of tissue that is of interest. A small fraction of diffusively scattered light is collected and measured. The tissue is pressured to temporarily squeeze blood out of the measured tissue volume while the reflection spectrum is continuously monitored, displayed, and analyzed in near real time. After an optimal time period of typically 15 seconds, the influence of the dominating hemoglobin and oxyhemoglobin tissue absorptions on the reflection spectra are minimized. | 12-27-2012 |
20120330165 | FLUOROSCOPY APPARATUS - A fluoroscopy apparatus is adopted which includes a fluorescence-image generating section that generates a fluorescence image of a subject, a white-light-image generating section that generates a white-light image of the subject, a fluorescence-image correcting section that generates a corrected fluorescence image in which luminance values of pixels are normalized by dividing the luminance values of the pixels of the fluorescence image by the luminance values of the pixels of the white-light image, an error-image identifying section that standardizes white-light-image acquisition conditions and identifies an error region, which is a region in which the luminance values of the corrected fluorescence image exceed a preset allowable error range, on the basis of a gray level of the normalized white-light image, and a monitor that displays the error region. | 12-27-2012 |
20130006116 | SYSTEM AND METHOD FOR SUB-SURFACE FLUORESCENCE IMAGING - Methods for quantifying fluorescence and optical properties in a turbid medium such as tissue. Devices and systems suitable for the methods are also disclosed. | 01-03-2013 |
20130006117 | FLUORESCENCE ENDOSCOPE APPARATUS - A fluorescence-spectrum-recording unit, a fluorescence-image-acquiring unit, and a fluorescent-dye-density-calculating unit are comprised, the calculating unit calculates the densities D1 to Dm of fluorescent dyes 1 to m in each of all the pixels and in all of the pixels with the following equation, and, when there exists a pixel in which one of the calculation values of these densities is smaller than 0, a set value larger than the calculation value smaller than 0 is substituted for the density the calculation value of which is smaller than 0 in the equation, and the densities of the other fluorescent dyes are recalculated, relative to the pixel: | 01-03-2013 |
20130006118 | RADIATIVE FIBERS - The present invention relates inter alia to light emitting fibers for the application in general lighting, display backlit, information display, and for treatment and/or prophylaxis and/or diagnosis of diseases and/or cosmetic conditions. The fibers can be used for the preparation of any kind of canvas and light emitting devices. | 01-03-2013 |
20130006119 | FIBERS IN THERAPY AND COSMETICS - The present invention relates inter alia to functional materials for the treatment and/or prophylaxis and/or diagnosis of diseases and/or cosmetic conditions. The functional materials can be used for the preparation of light emitting devices comprising fibers as light emitting elements. | 01-03-2013 |
20130006120 | MARKER FOR A MEDICAL NAVIGATION SYSTEM WITH A LASER TRACKER - A medical navigation system, comprising at least one laser scanner, at least one marker and a processing unit, wherein a laser scanner comprises a laser for generating a laser beam and a laser positioning unit for varying the direction of the laser beam in at least one dimension, wherein a marker comprises a detector for the laser beam and is configured to send an information signal to the processing unit when the laser beam hits the detector, and wherein the processing unit is configured to calculate the location of a marker from the information signal sent by the marker. | 01-03-2013 |
20130012822 | APPARATUS FOR MEASURING THE LUMINANCE AND TEMPERATURE OF A LIGHT SOURCE OF A SPECTROPHOTOMETRIC DEVICE - A system for measuring the luminance and temperature of a light source element of a spectrophotometric device is provided. The system includes a photodiode, a luminance measuring device, a temperature measuring device, a first switch, and a controller. The photodiode is operable to receive light signals emitted by the light source element and passing through a subject's body tissue. The luminance measuring device is operable to measure luminance of the light signals received by the photodiode. The temperature measuring device is operable to measure the temperature of the photodiode. The first switch is operable to connect the photodiode to the luminance measuring device or the temperature measuring device. The controller is operable to control the connection of the first switch. | 01-10-2013 |
20130018270 | OPTICAL OBSERVATION SYSTEM AND METHOD OF OBSERVING EXAMINATION SUBJECTAANM MIZUNAKA; MasaruAACI TokyoAACO JPAAGP MIZUNAKA; Masaru Tokyo JPAANM MURAYAMA; MasanoriAACI Wako-shiAACO JPAAGP MURAYAMA; Masanori Wako-shi JPAANM MIYAWAKI; AtsushiAACI Wako-shiAACO JPAAGP MIYAWAKI; Atsushi Wako-shi JP - Provided is an optical observation system that is provided with a portable device, which is secured to an examination subject A and is moved together with the movement of the examination subject, and an external device disposed away from the examination subject, wherein the portable device is provided with a light source; an illumination optical system radiates light coming from the light source onto an observation target site in the examination subject; a detection optical system optically guides light coming from the observation target site; a photodetector detects the light optically guided thereto by the detection optical system and converts the light to an electrical signal; and a transmitter wirelessly transmits the electrical signal output from the photodetector; and the external device is provided with a receiver receives the electrical signal transmitted from the portable device and a signal processor processes the electrical signal received by the receiver. | 01-17-2013 |
20130018271 | METHODOLOGY AND APPARATUS FOR OBJECTIVE ASSESSMENT AND RATING OF PSORIASIS LESION THICKNESS USING DIGITAL IMAGINGAANM Mohamad Hani; Ahmad FadzilAACI TronohAACO MYAAGP Mohamad Hani; Ahmad Fadzil Tronoh MYAANM Fitriyah; HurriyatulAACI TronohAACO MYAAGP Fitriyah; Hurriyatul Tronoh MY - The present invention relates generally to a method and apparatus for assessing data from digital images of psoriasis lesion for said psoriasis lesion thickness by utilizing a developed computer vision system to obtain Psoriasis Area and Severity Index (PASI) parameters in particular. | 01-17-2013 |
20130023774 | MINIATURE SPECTROMETER - A miniaturized spectrometer is adapted for placement within a body near tissue to be characterized. The spectrometer includes a light source and a plurality of light detectors. The light source generates light to illuminate the tissue. The detectors detect optical signals from the illuminated tissue and convert these optical signals to electrical signals. The miniaturized spectrometer can be disposed at the distal end of an interventional device. Optical conduits, such as fiber optic cables or strands, extending the length of the interventional device are not required when the miniature spectrometer is employed. | 01-24-2013 |
20130030305 | METHOD AND SYSTEM FOR DETERMINING A STAGE OF FIBROSIS IN A LIVER - A method for determining a stage of fibrosis in a liver is disclosed. The method comprises the steps of: (1a) obtaining input data relating to the liver, the input data being generated using a second harmonic generation based imaging system; (1b) identifying a plurality of morphological features of the liver from the input data relating to the liver; (1c) generating a plurality of measurements based on the identified plurality of morphological features; and (1d) determining the stage of fibrosis in the liver based, on the generated plurality of measurements. | 01-31-2013 |
20130035598 | IMAGING DEVICE FOR USE WITH A SURGICAL DEVICE - a surgical imaging device is provided, including a housing configured to couple to an outer surface of a surgical device and an image capture arrangement configured to generate image data; the surgical imaging device may also include a circuit arrangement disposed within the housing and electrically coupled to the camera arrangement, in which the circuit arrangement is configured to communicate the image data to at least one remote device. | 02-07-2013 |
20130035599 | RESPIRATORY MOTION DETECTION APPARATUS - The invention relates to a respiratory motion detection apparatus ( | 02-07-2013 |
20130041267 | METHOD AND DEVICE FOR MULTI-SPECTRAL PHOTONIC IMAGING - An imaging device for medical imaging includes a light source device arranged to illuminate a sample under investigation with illumination light, a detector device arranged to collect a plurality of images including at least two sample light images backscattered by the sample in different spectral ranges, and at least one marker light image originating from at least one marker substance in the sample, and a processor device adapted to process the at least two sample light images and create at least one correction component, the processor device further adapted to correct the marker light image using the at least one correction component. | 02-14-2013 |
20130046183 | WEARABLE VISION DEVICE - The present invention aims to provide alternative means for the diagnosis of the risk of developing mouth mucosa cancers by means of fluorescence, easy to use, simple, light and space-saving and diagnostic kits comprising the above-mentioned device. | 02-21-2013 |
20130046184 | METHOD OF ANALYZING AND PROCESSING SIGNALS - A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component. | 02-21-2013 |
20130046185 | METHOD OF ANALYZING AND PROCESSING SIGNALS - A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component. | 02-21-2013 |
20130046186 | METHOD OF ANALYZING AND PROCESSING SIGNALS - A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component. | 02-21-2013 |
20130053699 | APPARATUS AND METHOD FOR PERFORMING PHOTODYNAMIC DIAGNOSIS AND PHOTODYNAMIC THERAPY - An apparatus for performing photodynamic diagnosis and photodynamic therapy on a target region that is pre-given with a photosensitizer precursor includes a display unit, an excitation light source operable to irradiate the target region with exciting light so as to excite emission of fluorescence from the target region as a result of fluorescence response of the photosensitizer precursor, an image capturing unit operable to capture a white light image and a fluorescent image of the target region, an image processing unit operable to superimpose the white light image and the fluorescent image into a synthesized image and to provide at least one of the white light image, the fluorescent image and the synthesized image thereto for display on the display unit, and a curing light source operable to irradiate a specified portion of the target region with curing light for treating the specified portion. | 02-28-2013 |
20130053700 | ALGORITHM FOR DETECTION OF DIABETES - Methods for spectroscopic analysis of biological tissues to classify an individual as diabetic or non-diabetic, or to determine the probability, progression or level of a disease or medical condition in an individual. | 02-28-2013 |
20130053701 | DERMATOSCOPE AND ELEVATION MEASURING TOOL - A dermatoscope is in the form of a handheld device is provided. The dermatoscope comprising a display which is arranged in or on a housing, for an image of the skin surface and/or of a structure of the skin surface which is recorded by a surface sensor of the dermatoscope, and a storing means for storing the images recorded by the dermatoscope. | 02-28-2013 |
20130053702 | CALIBRATION-FREE AND PRECISE OPTICAL DETECTION OF A THREE-DIMENSIONAL SHAPE - A support plate with a horizontal flat standing surface carries two posts, and is rotated about a vertical axis. A stationary triangulation measuring head having a camera and a light line projector, projects light lines, which are perpendicular to the plane of the support plate, onto a person who stands upright on the standing surface of the plate. Encoded, photogrammetrically evaluatable marks are arranged on the plate around the standing surface and on the post. Images taken by the camera during rotation of the plate are transferred to a computer to determine a three-dimensional shape of the person or of part of the person. Marking-free fields are arranged on the support plate and on the post. The computer determines the parameters of the triangulation measuring head to performs a self-calibration of the detection process based on positions of the photogrammetric marks and shapes of light traces on the marking-free fields. | 02-28-2013 |
20130053703 | ENDOSCOPIC DIAGNOSIS SYSTEM - An endoscopic diagnosis system includes a light source unit for emitting green and red light, blue and green light, or white light and excitation light having different central wavelengths for causing an autofluorescent substance to emit autofluorescence, an imaging unit for receiving reflected light from the observation region to acquire a reflected light image when the observation region is illuminated with the illumination light emitted, and receiving autofluorescence that is emitted from the autofluorescent substance, absorbed by blood, and decreases according to the amount of the blood to acquire an autofluorescence image when the observation region is irradiated with the excitation light emitted, and an image correction unit for correcting the autofluorescence image based on the reflected light image. | 02-28-2013 |
20130060146 | SYSTEM AND METHODS FOR INTRAOPERATIVE GUIDANCE FEEDBACK - Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture. | 03-07-2013 |
20130066214 | HOLDER AND LIGHT MEASURING DEVICE USING SAME - Provided is a holder which comprises at least two probe mount portions and is to be put on the head of a subject by inserting a light-transmitting probe for emitting light from the tip thereof or a light-receiving probe for receiving light through the tip thereof in the probe mount portion, the holder characterized by being provided with a linear backbone portion extending in a first direction, at least two linear branch portions extending in a second direction different from the first direction, and a disposition reference point disposed so as to match a first specific point, the first specific point being set in the head of the subject. | 03-14-2013 |
20130072803 | SKIN OPTICAL CHARACTERIZATION DEVICE - The present invention is generally directed to dermatological devices and methods in which one or more skin characteristics, such as the melanin index, are determined by analyzing radiation backscattered from a skin region illuminated by at least one, and preferably, two or more wavelengths, e.g., in a range of about 600 nm to about 900 nm. In many embodiments, the radiation is coupled to the skin via a waveguide, and an optical sensor is employed to ascertain contact between the waveguide (e.g., a waveguide surface adapted for contact with the skin) and the skin. | 03-21-2013 |
20130072804 | LIGHT TRANSMITTING PROBE, LIGHT RECEIVING PROBE, LIGHT TRANSMITTING AND RECEIVING PROBE, AND LIGHT MEASUREMENT DEVICE USING SAME - A light transmitting probe comprising: a housing for fixing the probe to a mounting portion of a holder to be mounted on a subject; a light emitter for emitting light, the light emitter being placed in an end portion of the housing; and a transmission channel, one end of which is connected to the light emitter, and the other end of each is connected to a controller; the light transmitting probe irradiating the subject with light when fixed to the holder, and being characterized in that the end portion of the housing has a number of rod-shaped protrusions, the light emitter is a number of light emitting elements, the light emitting elements are respectively placed in an end portion of each protrusion, the transmission channel is a number of transmission channels, and the transmission channels are respectively placed inside each protrusion. | 03-21-2013 |
20130079644 | Optical Probe with Electric Motor - Optical probes may be used to capture images of a subject. An optical probe may include an optical reflector, an optical waveguide, and an electric motor. A rotor of the electric motor is mechanically coupled with the optical reflector to rotate the optical reflector in response to an input electric current. The optical waveguide is optically coupled with the optical reflector. The optical waveguide may output light to the optical reflector which directs the light to the subject. Light may then reflect back from the subject to the optical reflector which directs the reflected light from the subject to the optical waveguide. | 03-28-2013 |
20130085397 | OPTICAL FIBER INSTRUMENT SYSTEM AND METHOD WITH MOTION-BASED ADJUSTMENT - An instrument system that includes an optical fiber and a controller is provided. The optical fiber is coupled to an external structure of a patient and has a strain sensor provided thereon. The controller is operatively coupled to the optical fiber and adapted to receive a signal from the strain sensor and to determine a property of respiration of the patient based on the signal. | 04-04-2013 |
20130102906 | ILLUMINATOR FOR PHOTODYNAMIC THERAPY - An apparatus and method for photodynamic therapy or photodynamic diagnosis using an illuminator comprising a plurality of light sources generally conforming to a contoured surface and irradiating the contoured surface with substantially uniform intensity visible light. The light sources may comprise generally U-shaped fluorescent tubes that are driven by electronic ballasts. The spacing of the U-shaped tubes is varied to increase the output at the edges of the illuminator to make the output more uniform. Also, different portions of the tubes are cooled at different amounts, to improve uniformity. A light sensor monitors output from the U-shaped tubes to provide a signal for adjusting the output from the tubes. | 04-25-2013 |
20130102907 | BIOLOGICAL PHOTOMETRIC DEVICE AND BIOLOGICAL PHOTOMETRY METHOD USING SAME - The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components. | 04-25-2013 |
20130109977 | UV IMAGING FOR INTRAOPERATIVE TUMOR DELINEATION | 05-02-2013 |
20130116574 | METHOD FOR ASCERTAINING SPATIAL COORDINATES - The invention relates to a method for ascertaining spatial coordinates in which at least two markers are put on a living being and at least two cameras in a stereo arrangement are used to ascertain the spatial coordinates of the markers, wherein the spatial coordinates of the markers are compared with a reference and the difference is calculated and output. The invention also relates to quantitative length and angle measurements using optical, stereometric measurement systems for medical applications. | 05-09-2013 |
20130123641 | METHOD AND APPARATUS FOR ANALYZING SUBSURFACES OF A TARGET MATERIAL - A system that incorporates teachings of the present disclosure may include, for example, a method for aligning first and second light signals on an optical path directed to a target, where the first light signal provides a visualization of the target, and a portion of the second light signal reflects from at least one subsurface of the target. The method also includes aligning a first focal point of the first light signal and a second focal point of the second light signal, where the first focal point is at least in a first proximate location of the second focal point, and adjusting a first position of the first and second focal points to be in at least a second proximate location of the target without adjusting the at least first proximate location of the first focal point relative to the second focal point. Other embodiments are disclosed. | 05-16-2013 |
20130123642 | ESTIMATING APPARATUS AND ESTIMATING METHOD - A photodynamic therapy apparatus as an estimating apparatus is an apparatus for irradiating a tissue having absorbed photo-sensitive pharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser the catheter, including a connector, a light source, and a light detection unit. The laser the catheter is capable of being attached/detached to/from the connector. The light source outputs the excitation light to the laser the catheter via the connector. The light detection unit detects intensity or a spectrum of the fluorescence, the fluorescence being entered from the laser the catheter via the connector, to estimate whether the tissue has changed because of reaction between the excitation light emitted from the tip portion of the laser the catheter and the photo-sensitive pharmaceutical absorbed in the tissue. | 05-16-2013 |
20130123643 | MEASURING ARRANGEMENT FOR RECORDING A SPECTRUM, IN PARTICULAR FROM VITAL TISSUE - The invention relates to a measuring arrangement having a mobile spectrometer device which comprises a measuring head structure, wherein the measuring head structure is designed in such a way that, to carry out the spectrometric measurement, it can be placed on a portion of tissue, and a socket element which forms an inner receiving space into which the measuring head structure can be inserted, wherein a calibrating medium, produced from an opaque material, is arranged in a bottom region bounding the inner receiving space, and the socket element and the measuring head structure are designed such that, after the measuring head structure has been introduced into the socket element, the calibrating medium is sealed off in a light-tight manner from the surroundings. | 05-16-2013 |
20130123644 | OPTICAL MEASUREMENT APPARATUS, ENDOSCOPE SYSTEM, AND COMPUTER READABLE STORAGE MEDIUM - An optical measurement apparatus of the present invention includes a light source unit; an operation unit that performs an operation process on the basis of a result of the measurement performed by a measurement unit to obtain a characteristic value of a living tissue; a validity evaluator that evaluates, on the basis of an operation result of the operation process performed by the operation unit, whether the result of the measurement is valid; an output unit that outputs a result of the evaluation performed by the validity evaluator; an input unit that inputs an instruction to adopt the result of the measurement performed by the measurement unit; and a determination unit that determines, on the basis of the result of the evaluation performed by the validity evaluator and the instruction information from the input unit, whether to adopt the result of the measurement performed by the measurement unit. | 05-16-2013 |
20130123645 | Kinematic System - A kinematic system is described. The kinematic system includes a kinematic device for attachment to a subject's body part. The kinematic device projects a light line, and a movement of the light line is used to evaluate a movement, posture, or balance of the subject. | 05-16-2013 |
20130123646 | METHOD AND ELECTRONIC DEVICE FOR REMOTE DIAGNOSIS - The present invention relates to a remote treatment method and an electronic device. More specifically, the present invention provides a remote treatment method and an electronic device that guide a manipulation of a checkup tool. | 05-16-2013 |
20130131519 | LIGHT-GUIDING DEVICES AND MONITORING DEVICES INCORPORATING SAME - A monitoring device configured to be attached to the ear of a person includes a base, an earbud housing extending outwardly from the base that is configured to be positioned within an ear of a subject, and a cover surrounding the earbud housing. The base includes a speaker, an optical emitter, and an optical detector. The cover includes light transmissive material that is in optical communication with the optical emitter and the optical detector and serves as a light guide to deliver light from the optical emitter into the ear canal of the subject wearing the device at one or more predetermined locations and to collect light external to the earbud housing and deliver the collected light to the optical detector. | 05-23-2013 |
20130137991 | HANDHELD SKIN MEASURING OR MONITORING DEVICE - A handheld skin monitoring or measuring device includes a camera having a camera optical axis; and a structured light arrangement configured to project three or more laser fan beams such that the laser fan beams cross at a crossing point in front of the camera. | 05-30-2013 |
20130137992 | PAIN-RELIEF DEVICE - Existing pain-relief devices have the problem that the use thereof requires specialized knowledge of Eastern acupuncture, e.g. meridians and acupuncture points, making it difficult for ordinary people to use said devices to relieve pain in painful areas. The disclosed pain-relief device is provided with: a small camera that, in step ST | 05-30-2013 |
20130137993 | OPTICAL CAPSULE AND SPECTROSCOPIC METHOD FOR TREATING AND DIAGNOSING THE INTESTINAL TRACT - A device and method for mapping, diagnosing and treating disorders or other diseases, disorders or conditions (e.g., bleeding, ischemic or necrotic tissue, and presence of certain chemicals or substances) of the intestinal tract is provided using a capsule passing through the intestinal tract and sensing optical characteristics as the capsule passes through. Further, a capsule tracking system is provided for tracking a capsule's location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule. A map of optical characteristics may be derived from the pass of a capsule to diagnose the disorder or disease. The capsule or subsequently passed capsules may treat, further diagnose or mark the intestinal tract at a determined location along its length. | 05-30-2013 |
20130150728 | MEDICAL APPARATUS - A medical apparatus has a light source section capable of irradiating an excitation light and a reference light alternately, an image pickup section that picks up images of fluorescence by the excitation light, and reflected light of the reference light, a pixel addition processing section that performs pixel addition processing of making a plurality of pixels in a first image as a fluorescence image one pixel, and generates a second image, an adjusting section that makes adjustment so that a brightness ratio of the second image and a reference light image obtained by picking up of the image of the reflected light has a constant value, and thereby generates a third image signal and a fourth image, an interpolation processing section that applies interpolation processing to the third image, and generates a fifth image, and an image processing section that performs image synthesis of the fifth image and the fourth image. | 06-13-2013 |
20130150729 | Sanitary cover sleeve for medical device with electrical contact - A disposable cover sleeve serves is used to cover an electronic or optical medical device used for patient examination and/or treatment. The cover sleeve provides an environmental barrier for the medical device during patient examination to prevent environmental cross-contamination of different patients examined with the same medical device. The cover sleeve has an integrated device activation means such as a flexible contact bridge. The device activation means has an open and closed position. The open position is not in physical, electronic or magnetic contact with the control electronics of the medical device; whereas, the closed position closes a field or circuit between a first and second contact to selectively actuate or provide input to the control electronics that communicate with the radiation source. | 06-13-2013 |
20130150730 | COOLING SYSTEM FOR A PHOTOCOSMETIC DEVICE - Photocosmetic device for use in medical or non-medical environments (e.g., a home, barbershop, or spa), which can be used for a variety of tissue treatments. Radiation is delivered to the tissue via optical systems designed to pattern the radiation and project the radiation to a particular depth. The device has a variety of cooling systems including phase change cooling solids and liquids to cool treated skin and the radiation sources. Contact sensors and motion sensor may be used to enhance treatment. The device may be modular to facilitate manufacture and replacement of parts. | 06-13-2013 |
20130158412 | TISSUE INTERFACE SYSTEMS FOR OPTICAL MEASUREMENT OF PHYSIOLOGICAL BLOOD PARAMETERS - Systems and methods for measuring a physiological parameter of tissue in a patient are provided herein. In a first example, tissue interface pad for applying optical signals to tissue of a patient is provided. The tissue interface pad includes a first surface configured to interface with the tissue of the patient and further includes a first guide channel disposed generally parallel to a second guide channel. The first guide channel is configured to route an input optical fiber to a first location and optically couple an end of the input optical fiber to the tissue at the first location. The second guide channel is configured to route an output optical fiber to a second location and optically couple an end of the output optical fiber to the tissue at the second location. | 06-20-2013 |
20130158413 | OPTICAL MEASUREMENT OF PHYSIOLOGICAL BLOOD PARAMETERS - Systems and methods for measuring a physiological parameter of tissue in a patient are provided herein, such as a system to optically analyze tissue of a patient. An example system includes a tissue interface assembly configured to emit an input optical signal into the tissue, receive a reference optical signal and a measurement optical signal from the tissue, and transfer the reference optical signal and the measurement optical signal to the optical link. The optical link is configured to transfer the reference optical signal and the measurement optical signal. The transceiver is configured to receive and convert the optical signals into digital signals. | 06-20-2013 |
20130165798 | DETECTING OPTICAL PROPERTIES OF A TURBID MEDIUM - Disclosed herein are methods and devices for evaluating the optical properties of a turbid medium, wherein the medium is one which both absorbs and scatters light. Turbid media of particular interest include fluids such as coolants, paints, etc., and biologically or medically relevant fluids, such as blood, culture media, etc. The methods and devices disclosed herein can also be used to measure changes in optical properties of a tissue (e.g., an epithelial layer) that are associated with a variety of disease states. Changes or differences in the optical properties of tissue can provide indicia of a pathological state or the efficacy of a therapeutic regimen. In general, the change or difference can be a change or difference relative to a standard that is either internal or external. Also disclosed herein are methods for obtaining absolute values for optical properties that are generally obtained as relative values. This absolute value can be compared effectively with an absolute value from another sample with meaningful results. | 06-27-2013 |
20130178748 | METHOD FOR IDENTIFYING MALIGNANCIES IN BARRETT'S ESOPHAGUS USING WHITE LIGHT ENDOSCOPY - A method is described for computing a statistically significant difference between dysplasia and Barrett's esophagus (both with and without inflammatory component) using a discriminate function with diffuse reflectance measurements performed at a minimum of four different wavelengths of 485, 513, 598, and 629 nm. The discriminate function found depends both on local blood fraction volume T | 07-11-2013 |
20130184592 | SYSTEM AND METHOD FOR HOME HEALTH CARE MONITORING - A home health care monitoring method and system are disclosed. In one embodiment, a method includes: capturing a plurality of video sequences from a plurality of respective cameras disposed in different locations within a patient's home, including capturing two-dimensional image data and depth data for each video sequence; defining a plurality of events to monitor associated with the patient, the events including, during a predetermined time period, at least (1) the patient's body being in a particular position for at least a predetermined amount of time; performing depth-enhanced video content analysis on the plurality of video sequences to determine whether the event (1) has occurred. The video content analysis may include: for each of at least two cameras: automatically detecting a human object based on the two-dimensional image data; using the depth data to confirm whether the human object is in the particular position; and based on the confirmation, tracking an amount of time that the human object is in the particular position; and then determining that the event (1) has occurred based on the collective tracked amount of time. | 07-18-2013 |
20130190628 | WIRE-TYPE WAVEGUIDE FOR TERAHERTZ RADIATION - In order to guide electromagnetic waves in the terahertz range over long distances of several meters with low bending losses and large bandwidth, a device, a system and a method are provided such that electromagnetic waves in the terahertz range can be coupled into a wire having a core structure and at least one confinement structure, wherein the confinement structure extends continuously along a length of the wire. | 07-25-2013 |
20130197370 | Automated Pneumothorax Detection - A method of determining the presence of a pneumothorax includes obtaining a series of frames of image data relating to a region of interest including a pleural interface of a lung. The image data includes at least a first frame and a second frame. The method further includes identifying, via processing circuitry, the pleural interface in at least the first frame and the second frame, determining, based on computing optical flow between the first and second frames, a pleural sliding classification of the image data at the pleural interface, and determining whether a pneumothorax is present in the pleural interface based on the pleural sliding classification. | 08-01-2013 |
20130197371 | DIAGNOSTIC SYSTEM - A diagnostic system comprises a spectral image shooting means that shoots a spectral image within a predetermined wavelength range in a body cavity and obtains spectral image data, an image processing means that obtains the spectral image data and calculates an indicator indicating an area having a high possibility of a diseased portion from the spectral image data, and a monitor on which the indicator is displayed, and wherein the image processing means calculates, as the indicator, a ratio between an accumulated value of intensity values of all spectral images in the predetermined wavelength range and an intensity value of spectral images in a particular wavelength band, for each coordinate in the spectral image. | 08-01-2013 |
20130197372 | DETECTION DEVICE, DETECTING METHOD, CONTROL PROGRAM AND RECORDING MEDIUM - A detection device ( | 08-01-2013 |
20130204141 | PHYSIOLOGICAL SENSOR - A sensor used to measure physiological characteristics of body tissues is provided. The physiological sensor includes a first light source assembly having a first light source in parallel with a second light source. Each of the first light source and the second light source have an anode and a cathode. A second light source assembly includes a third light source in parallel with a fourth light source. Each of the third light source and the fourth light source have an anode and a cathode. The anode of the first light source is electrically connected to the cathode of the second light source, the anode of said third light source, and the cathode of said fourth light source. The anode of the third light source is electrically connected to the cathode of the fourth light source. | 08-08-2013 |
20130211261 | MOTION COMPENSATION AND PATIENT FEEDBACK IN MEDICAL IMAGING SYSTEMS - An optical motion sensing system ( | 08-15-2013 |
20130218023 | METHODS FOR DIAGNOSIS OF COLORECTAL CANCER - Methods and systems for use of phenotypic markers, principally oral mucosal vascular density alone or in combination with detection of other markers, to identify individuals afflicted with or having an increased risk of hereditary colorectal cancer, especially familial adenomatous polyposis, are disclosed. | 08-22-2013 |
20130218024 | Interventional In-Situ Image-Guidance by Fusing Ultrasound and Video - An augmentation device for an imaging system has a bracket structured to be attachable to an imaging component, and a projector attached to the bracket. The projector is arranged and configured to project an image onto a surface in conjunction with imaging by the imaging system. A system for image-guided surgery has an imaging system, and a projector configured to project an image or pattern onto a region of interest during imaging by the imaging system. A capsule imaging device has an imaging system, and a local sensor system. The local sensor system provides information to reconstruct positions of the capsule endoscope free from external monitoring equipment. | 08-22-2013 |
20130218025 | CLIP SENSOR DEVICE FOR MEASUREMENT OF VITAL SIGNS - A clip sensor device for optical measuring vital signs of a subject is provided. The clip sensor device includes a internal supporting frame formed from an elongated plate configured to be folded into a desired orientation. A measuring probe is mounted on an upper surface of the frame. The measuring probe comprises a transmitter and receiver and configured for generating a time response of the blood perfused body tissue to the applied optical signal that is indicative of the vital signs of the subject. The clip sensor device also includes a pressing member mounted on the upper surface of the internal supporting frame. The pressing member includes one or more spring elements configured to provide a predetermined pressure on the blood perfused body tissue due to the deformation of the spring elements when said portion of blood perfused body tissue is applied against the pressing member. | 08-22-2013 |
20130226008 | Calculating Conjunctival Redness - The present application includes methods, systems and computer readable storage devices for determining a color score for at least a portion of a biological tissue. The subject matter of the application is embodied in a method that includes obtaining a digital image of the biological tissue, and receiving a selection of a portion of the image as an evaluation area. The method also includes determining for each of a plurality of pixels within the evaluation area, a plurality of color components that are based on a Cartesian color space, and determining, from the color components, a hue value in a polar coordinate based color space. The method further includes determining a color value based on the hue value for each of the plurality of pixels, and assigning a color score to the evaluation area based on an average of the color values of the plurality of pixels. | 08-29-2013 |
20130231573 | APPARATUS AND METHODS FOR CHARACTERIZATION OF LUNG TISSUE BY RAMAN SPECTROSCOPY - Near-infrared Raman spectroscopy can be applied to identify preneoplastic lesions of the bronchial tree. Real-time in vivo Raman spectra of lung tissues may be obtained with a fiber optic catheter passed down the instrument channel of a bronchoscope. Using prototype apparatus, preneoplastic lesions were detected with sensitivity and specificity of 96 and 91% respectively. The use of Raman spectroscopy apparatus and methods in conjunction with other bronchoscopy imaging modalities can substantially reduce the number of false positive results. | 09-05-2013 |
20130237842 | DETERMINING CONDITION OF TISSUE USING SPECTRAL ANALYSIS - A system for determining a condition of a tissue of a patient body is described. The tissue is illuminated with an illumination wavelength by a light source. In response to the illumination, the tissue emits light. This emitted light is received at a detector that includes multiple diode sensors. The diode sensors detect intensities of associated wavelengths of the emitted light. A spectral analysis is performed with the detected intensities. The spectral analysis includes initial coefficients. A composite function associated with the initial coefficients is minimized so as to determine wavelength coefficients. The wavelength coefficients are used to compute a score. Based on the score, the condition of the tissue is determined. Related methods, techniques, apparatus, and articles are also described. | 09-12-2013 |
20130237843 | TISSUE AND BONE GRAFT REMOVAL DEVICE - The present invention discloses a rongeur type bone and cartilage removal device incorporating a pistol shaped body exhibiting a forward extending barrel terminating in a powered saw drive including a plurality of blades. A passageway extends through an interior of the barrel and communicates the forward chain drive with a rearward positioned debris collection chamber. A power supply is incorporated into the body and, upon actuating a trigger, closes a circuit with the saw drive and a separate vacuum inducing drive in order to successively excise increments of bone for evacuation through the passageway and into the collection chamber. Another variant of the rongeur type bone removal device includes first and second pivotally secured handles, the first handle terminating at a forward end in a first jaw exhibiting a plurality of extending teeth, with second handle terminating in a second jaw opposing the first jaw and exhibiting a continuous blade edge against which the teeth seats during pivotal motion of the jaws. | 09-12-2013 |
20130237844 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237845 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237846 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237847 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237848 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237849 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237850 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a detector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The detector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237851 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237852 | Geometry of a Transcutaneous Sensor - A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237853 | Geometry of a Transcutaneous Sensor - A housing for a transcutaneous electromagnetic signal sensor including an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue. | 09-12-2013 |
20130237854 | Apparatus and Method for Mitigating Noise Affecting a Transcutaneous Signal - A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage. | 09-12-2013 |
20130237855 | Apparatus and Method for Mitigating Noise Affecting a Transcutaneous Signal - A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage. | 09-12-2013 |
20130237856 | Apparatus and Method for Mitigating Noise Affecting a Transcutaneous Signal - A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage. | 09-12-2013 |
20130237857 | Apparatus and Method for Mitigating Noise Affecting a Transcutaneous Signal - A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage. | 09-12-2013 |
20130237858 | Apparatus and Method for Mitigating Noise Affecting a Transcutaneous Signal - A system and method include a sensor overlying a target area of skin to aid in diagnosing subcutaneous fluid leakage. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of subcutaneous fluid leakage. | 09-12-2013 |
20130237859 | APPARATUS - Provided is an apparatus that can stably compress an inspection region and hence reduce a burden on a subject and a burden on an operator. | 09-12-2013 |
20130245458 | SYSTEM AND METHOD FOR DIAGNOSING AND TREATING DISEASE - A method and system for diagnosing and treating infection or disease, in which an individual takes a photograph of an infected or diseased area of a body using a camera connected to a microprocessor. The photograph is sent to a diagnosing center having a server with a second microprocessor and a database of photographs correlated with different diseases and infections. The second microprocessor scans the image received from the camera and compares it to the photographs in the database. If a match is found, the second microprocessor then notes the disease or bacteria corresponding to the matching photograph. The second microprocessor then searches an additional database correslated to the match, to further refine the diagnosis. The second microprocessor then searches the second database for a treatment corresponding to the identified disease or bacteria. Once a treatment is identified, information regarding this treatment is automatically sent to the individual's microprocessor. | 09-19-2013 |
20130245459 | Quantification of Under-Eye Skin Color - Methods for quantitative measurement of under eye dark circles and other color related phenomena in eye area skin are described. The methods can be used to quantify the clinical efficacy of skin care products. | 09-19-2013 |
20130245460 | Adjustable Overlay Patterns for Medical Display - A system for identifying an area of interest on a surgical image, including a source of surgical image data, which may be a camera, an image processing unit, which may be a camera control unit, and a destination, which may be a display. The image processing unit is configured to receive the surgical image data and combine it with an overlay pattern for identifying an area of interest, which is then displayed on the display. The overlay pattern may include centric lines, concentric ovals, concentric circles, or other concentric shapes. The overlay may include a key with coordinates or labels. Properties of the overlay and the key may be customized and adjusted. | 09-19-2013 |
20130245461 | Visualization of Anatomical Data by Augmented Reality - A sensor means is employed to sense a distance to the surface of a subject to be examined, so that a range image may be acquired. Intensity information may be acquired alongside the distance information. The distance information and intensity information may be evaluated to track the pose of the sensor means relative to the surface of the subject to be examined, so that anatomical data related to said subject may be displayed as seen from the position and/or orientation of the sensor means or display means. By moving the sensor means or display means along the surface of the subject to be examined, such as a patient in a hospital environment, the user hence gets the impression of being able to look directly into the human body. | 09-19-2013 |
20130253332 | TISSUE INTERFACE SYSTEMS FOR APPLICATION OF OPTICAL SIGNALS INTO TISSUE OF A PATIENT - Systems and methods for applying optical signals into tissue of a patient are provided herein. In one example, a tissue interface system for applying optical signals to tissue of a patient is provided. The tissue interface system includes a tissue interface pad configured to apply the optical signals carried by at least one optical source into the tissue, and a pressurized volume configured to apply pressure to the tissue interface pad to couple a portion of the tissue interface pad to the tissue. | 09-26-2013 |
20130253333 | TISSUE INTERFACE ELEMENTS FOR APPLICATION OF OPTICAL SIGNALS INTO TISSUE OF A PATIENT - Systems and methods for applying optical signals into tissue of a patient are provided herein. In one example, a tissue interface pad for applying an optical signal to tissue of a patient is provided. The tissue interface pad includes a first surface configured to interface with the tissue of the patient, at least one guide channel disposed within the tissue interface pad and configured to route an input optical fiber carrying the optical signal to a first location in the tissue interface pad, and a second surface at the first location configured to direct the optical signal from the input optical fiber into the tissue through the first surface. | 09-26-2013 |
20130253334 | WIRELESS PATIENT MONITORING DEVICE - A device for obtaining physiological information of a medical patient and wirelessly transmitting the obtained physiological information to a wireless receiver. | 09-26-2013 |
20130253335 | OPTICAL PROCESS AND APPARATUS FOR NON-INVASIVE DETECTION OF MELANOMA - A non-invasive, optical method and device for the detection of melanoma in skin lesions. The detection of the presence of melanoma is accomplished optically by looking for specific changes (signatures) in the spectrum of optical light elastically scattered off melanoma molecules. Elastic scattering spectroscopy (ESS) converts subcellular morphological changes into scattering spectrum signatures. A melanoma discrimination analysis is performed by illuminating the lesion with a handheld device that also collects a portion of the scattered light, converts it into digital signals, analyzes the requisite spectral signatures, and provides a logical output showing the user the presence (or absence) of melanoma in the subject lesion. | 09-26-2013 |
20130253336 | SENSOR, GAS ANALYZER AND METHOD FOR MEASURING CONCENTRATION OF AT LEAST ONE RESPIRATORY GAS COMPONENT - A sensor for measuring a concentration of a respiratory gas component is disclosed herein. The sensor comprises at least one radiation source configured to emit radiation and at least one radiation sensing detector configured to receive radiation and provide a signal indicative of the concentration of the gas component. The sensor further comprises an electronics board configured to receive and process the signal to determine the concentration, and an energy storage device configured to supply energy to the radiation source. The electronics board is configured to choose from among at least two different modes, one being an operation mode allowing sufficient energy supply to the radiation source, and another being a rest mode allowing reduced energy supply compared to the operation mode to limit radiation for saving energy within the breathing cycle. A gas analyzer and method for measuring a concentration of a respiratory gas component are also provided. | 09-26-2013 |
20130253337 | AUTOMATED ASSESSMENT OF SKIN LESIONS USING IMAGE LIBRARY - An automated skin lesion assessment system may automatically assess a suspect skin lesion. An electronic image library may contain diagnosed skin lesion image data representative of images of a plurality of diagnosed skin lesions and, for each, a diagnosis of the skin lesion. An image capture system may capture an image of the suspect skin lesion. A computer processing system may compare the image of the suspect skin lesion with the diagnosed skin lesion image data and, based on this comparison, identify one or more diagnosed skin lesions which match the suspect skin lesion. A user interface may report the diagnoses of the diagnosed skin lesions that match the image of the suspect skin lesion. | 09-26-2013 |
20130261469 | INTEGRATED SELF-FIXATING VISUALIZATION DEVICES, SYSTEMS AND METHODS - Surgical visualization devices are provided which include a substrate having at least one imaging device and a plurality of fasteners coupled thereto for attaching the substrate to patient tissue. Systems and methods utilizing the surgical visualization devices are also provided. | 10-03-2013 |
20130261470 | SYSTEMS AND METHODS FOR ESTIMATING BODY COMPOSITION - In one embodiment, a system and method for estimating body composition relate to constructing a three-dimensional model of a subject based upon captured images of the subject, estimating the body volume of the subject using the three-dimensional model, and estimating the body composition of the subject based in part upon the estimated volume. | 10-03-2013 |
20130267856 | OBJECT INFORMATION ACQUIRING APPARATUS - Provided is an object information acquiring apparatus including: an irradiating unit that irradiates an object with light; a probe that receives an acoustic wave generated from the object irradiated with the light; a generating unit that generates an image of the object interior on the basis of the acoustic wave; an imaging region input unit that receives an input of a designation of an imaging region, which is a region of the object in which the acoustic wave is received by the probe; a display region input unit that receives an input of a designation of a display region, which is a region of the object in which the image generated by the generating unit is displayed; and a display unit that displays the generated image in the display region. | 10-10-2013 |
20130274611 | OPTICAL INTERFACE SYSTEMS FOR APPLICATION OF OPTICAL SIGNALS INTO TISSUE OF A PATIENT - Systems and methods for applying optical signals onto tissue of a patient are provided herein. In one example, a system to optically analyze tissue of a patient is provided. The system includes a measurement system configured to transfer source optical signals over an optical link, receive measurement optical signals over the optical link, and identify a value of a physiological parameter of the patient. The optical link comprises a first source portion with a first link property configured to carry the source optical signals and a second source portion with a second link property coupled to the first source portion and configured to carry the source optical signals. The system includes a tissue interface assembly configured to receive the source optical signals transferred over the optical link, emit the source optical signals into the tissue, and receive the measurement optical signals from the tissue for transfer over the optical link. | 10-17-2013 |
20130274612 | METHOD AND APPARATUS FOR ANALYSIS OF TURBID MEDIA VIA SINGLE-ELEMENT DETECTION USING STRUCTURED ILLUMINATION - Method and apparatus for obtaining qualitative and quantitative analysis of the optical properties or structures of tissue or turbid medium at one or more wavelengths via 1) detection at a single spatial location on the surface of a turbid medium (such as tissue) under two or more structured light conditions or 2) detection at two or more spatial locations on the surface under a single structured light condition. | 10-17-2013 |
20130281865 | TRANSMITTED LIGHT DETECTION TYPE MEASUREMENT APPARATUS FOR SKIN AUTOFLUORESCENCE - The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator. | 10-24-2013 |
20130289413 | SYSTEMS AND METHODS FOR IDENTIFYING PORTIONS OF A PHYSIOLOGICAL SIGNAL USABLE FOR DETERMINING PHYSIOLOGICAL INFORMATION - A patient monitoring system may determine portions of a PPG signal that correspond to artifacts, to a baseline shift that exceeds a threshold, or to a pulse-to-pulse variability that exceeds a threshold. The patient monitoring system may identify a contiguous portion of the PPG signal that does not include the determined portions. The contiguous portion of the PPG signal may be used to determine physiological information. | 10-31-2013 |
20130289414 | COMBINED ABSORPTION-REFLECTION BASED INSTRUMENT AND TECHNIQUE TO MEASURE ANTIOXIDANTS (INCLUDING CAROTENOIDS) IN HUMAN TISSUE - A combined absorption-reflection based instrument and methods are introduced here to measure antioxidant carotenoids and similar compounds such as: beta-carotene, lycopene and lutein, along with others in living human tissue (e.g. skin). The device and methods provide a non-invasive, rapid, accurate, repeatable, safe and reliable method for measuring antioxidant levels in human tissue, providing information that can be used for many diagnostic and/or health purposes. | 10-31-2013 |
20130289415 | In Vivo Examination Apparatus and Capsule Endoscope - Provided is an in vivo examination apparatus including an illumination unit emitting two types of illumination light in different wavelength bands; and an image acquisition unit having sensitivity to the wavelength bands of the two types of illumination light. Blood and background tissue have higher reflectances than a predetermined threshold to illumination light in a first wavelength band, blood has a lower reflectance than the threshold to illumination light in a second wavelength band, and a condition (R1b/R1a)>(R2b/R2a) is satisfied, where R1a is the reflectance of the background tissue to the illumination light in the first wavelength band, R1b is the reflectance of the blood to the illumination light in the first wavelength band, R2a is the reflectance of the background tissue to the illumination light in the second wavelength band, and R2b is the reflectance of the blood to the illumination light in the second wavelength band. | 10-31-2013 |
20130289416 | SKIN ULCER TREATMENT - A system and method for facilitating the healing of a skin ulcer, such as a diabetic ulcer, on a treatment region of a body. Ultrasound waves are transmitted to the treatment region. Interferential electrical stimulation is applied to the treatment region, simultaneously with the ultrasound transmission. The treatment region may be massaged with a massaging device during the treatment session. A gel may be applied onto the treatment region to facilitate the ultrasound transmission and electrical stimulation. A measurement system may be used to obtain accurate measurements of the skin ulcer, to provide a quantitative determination of the healing progression. | 10-31-2013 |
20130296708 | DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS - A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target. | 11-07-2013 |
20130296709 | DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS - A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target. | 11-07-2013 |
20130296710 | DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS - A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target. | 11-07-2013 |
20130296711 | SYSTEM AND APPARATUS FOR AUTOMATED TOTAL BODY IMAGING - An imaging station/booth for automated total body imaging having a small footprint and capable of quickly, efficiently, effectively, and consistently capturing multiple body images of a user or patient over time with minimal assistance from medical staff. | 11-07-2013 |
20130310696 | PRESSURE ULCER DETECTION SYSTEMS AND METHODS - Pressure ulcer detection systems and related methods are disclosed. Images of a patient supported by a person support apparatus are captured and analyzed to identify areas of the patient's skin which have a color different from surrounding areas of the patient's skin by a predetermined amount. A dielectric material attached with a positively charged electrode and a negatively charged electrode is configured to be in contact with the patient's skin. Differences in electric potential between areas of skin relative to surrounding areas of skin are identified. | 11-21-2013 |
20130310697 | DEVICE AND METHOD FOR DETERMINING A DISEASE ACTIVITY - A system and method to determine a disease activity as a single value by way of optical measurements in order to facilitate an analysis of a current disease status and a future course of disease, thus assisting a doctor's diagnosis or decision on a therapy. A blood perfusion is varied in an area of interest, the area of interest is irradiated with light of at least two wavelengths, an intensity of light reflected and/or transmitted by the area of interest is detected, features are derived from detected intensity curves of at least two predetermined wavelengths under at least two different perfusion conditions, and the disease activity is determined using these features. | 11-21-2013 |
20130317369 | DEVICES, SYSTEMS, AND METHODS FOR VIRTUAL STAINING - The disclosure herein provides methods, systems, and devices for virtually staining biological tissue for enhanced visualization without use of an actual dye or tag by detecting how each pixel of an unstained tissue image changes in waveform after staining with a certain dye(s) and/or tag(s) or other transformation under a certain electromagnetic radiation source, developing a virtual staining transform based on such detection, and applying such virtual staining transform to an unstained biological tissue to virtually stain the tissue. | 11-28-2013 |
20130317370 | CONTOURED PROTRUSION FOR IMPROVING SPECTROSCOPIC MEASUREMENT OF BLOOD CONSTITUENTS - A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector. | 11-28-2013 |
20130317371 | ENDOSCOPE APPARATUS - An endoscope apparatus for generating an image of a target site containing a fluorescent substance, including an image pickup section provided with pixels for generating image pickup signals corresponding to a red color region and a band closer to a long wavelength side than the red color region and pixels for generating an image pickup signal corresponding to a band closer to a short wavelength side than the red color region, a light source section emitting to the target site, excitation light for exciting the fluorescent substance and generating fluorescence and reference light for generating reflected light from the target site, and an image processing unit that acquires an image obtained by separating a signal component generated upon receiving the fluorescence from the image pickup signal generated by the image pickup section and an image obtained by separating a signal component generated upon receiving the reflected light. | 11-28-2013 |
20130324855 | METHODS AND SYSTEMS FOR POWER OPTIMIZATION IN A MEDICAL DEVICE - A physiological monitoring system may use photonic signals to determine physiological parameters. The system may vary parameters of a light drive signal used to generate the photonic signal from a light source such that power consumption is reduced or optimized. Parameters may include light intensity, firing rate, duty cycle, other suitable parameters, or any combination thereof. In some embodiments, the system may use information from a first light source to generate a light drive signal for a second light source. In some embodiments, the system may vary parameters in a way substantially synchronous with physiological pulses, for example, cardiac pulses. In some embodiments, the system may vary parameters in response to an external trigger. | 12-05-2013 |
20130324856 | METHODS AND SYSTEMS FOR POWER OPTIMIZATION IN A MEDICAL DEVICE - A physiological monitoring system may use photonic signals to determine physiological parameters. The system may vary parameters of a light drive signal used to generate the photonic signal from a light source such that power consumption is reduced or optimized. Parameters may include light intensity, firing rate, duty cycle, other suitable parameters, or any combination thereof. In some embodiments, the system may use information from a first light source to generate a light drive signal for a second light source. In some embodiments, the system may vary parameters in a way substantially synchronous with physiological pulses, for example, cardiac pulses. In some embodiments, the system may vary parameters in response to an external trigger. | 12-05-2013 |
20130324857 | AUTOMATED SYSTEM FOR WORKSPACE, RANGE OF MOTION AND FUNCTIONAL ANALYSIS - A portable and automated system and method for measuring physical function utilizing a contactless and vision-based sensor system for acquiring human movements and methods for the analysis of reachable or functional workspace and range of motion that can be used in tele-medicine applications, such as remote functional assessment and diagnosis. An interactive, shared virtual 3D environment is provided where the patient can follow the movement directions provided by a remote physician while body kinematics are extracted from depth sensing cameras and wireless sensors. | 12-05-2013 |
20140005555 | OPTICAL ASSEMBLY PROVIDING A SURGICAL MICROSCOPE VIEW FOR A SURGICAL VISUALIZATION SYSTEM | 01-02-2014 |
20140005556 | PHOTOACOUSTIC MEASURING APPARATUS | 01-02-2014 |
20140012137 | Hand-Held Dual-Magnification Dermatoscope - A one-piece hand-held dermatoscope have two magnifier lenses, a larger rectangular-shaped lens between two and three times magnification power, and a smaller circular lens between eight and 15 times magnification power. A polarizer is position between the lens and a patient's skin. In one embodiment, the polarizer is radial, such that cross-polarization is achieved when the light reflect off the skin and passes through it a second time. In another embodiment, the portion of the polarizer through which the light passes to the skin is linear in a first direction, and the portion through which the light passes back from the skin is linear in a second direction that is perpendicular to the first direction, enabling cross-polarization. | 01-09-2014 |
20140012138 | APPARATUS, SYSTEM AND METHOD FOR PROVIDING AN IMAGING DEVICE FOR MEDICAL APPLICATIONS - An apparatus, system and methods for providing and reclaiming a single use imaging device for sterile environments is disclosed and described. The system may include a single use high definition camera used for general purpose surgical procedures including, but not limited to: arthroscopic, laparoscopic, gynecologic, and urologic procedures, may comprise an imaging device that is a sterile and designed to ensure single use. The imaging device may have a single imaging sensor, either CCD or CMOS, encased in a housing. | 01-09-2014 |
20140012139 | SURGICAL CAMERA ASSEMBLIES AND SYSTEMS - A surgical camera assembly includes a camera member and a receptacle member. The camera member includes a camera head and a shaft. The shaft includes at least one electrical contact positioned towards a free end thereof. The at least one electrical contact is electrically coupled to the camera head. The receptacle member is configured to releasably receive the free end of the shaft and includes at least one electrical contact that is configured to electrically couple to the at least one electrical contact of the shaft to establish electrical communication between the camera head and the receptacle member when the free end of the shaft is received within the receptacle member. | 01-09-2014 |
20140012140 | Systems and Methods for Projecting Hyperspectral Images - The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease and cancer, that incorporate hyperspectral or multispectral imaging. | 01-09-2014 |
20140012141 | OPTICAL TOMOGRAPHIC IMAGING OTOSCOPE WITH INTEGRATED DISPLAY AND DIAGNOSIS - A diagnosis-and-display integrated optical tomographic imaging otoscope for examining otitis media. A hollow casing includes an ear specular disposed on a front surface, a display including an LCD disposed on a rear surface, and a manipulating handle on a lower part. An image-photographing part includes a CCD camera inside the casing, and photographs an ear drum image of a patient through the ear specular. A section-photographing part includes a collimator and a galvanometer mirror inside the casing, and photographs section images of the ear drum and a middle ear of the patient. The ear drum image obtained by the image-photographing part and the section images of the ear drum and the middle ear are obtained in a non-incision method by the section-photographing part, and are displayed in real time on the LCD such that desirable images can be stored. | 01-09-2014 |
20140018684 | LAPAROSCOPIC SURGICAL SCAFFOLD - A collapsible scaffolding can collapse for deployment to a laparoscopic surgical site through a trocar or the like, and can expand to provide a surface for organ retraction within a body cavity. In the expanded state, the scaffolding may assist a surgical procedure in a variety of ways, such as by providing a rigid structure upon which to secure retracted organs or surgical tools such as lights, cameras, and so forth. | 01-16-2014 |
20140018685 | OPTICAL INSPECTION DEVICE, ELECTROMAGNETIC WAVE DETECTION METHOD, ELECTROMAGNETIC WAVE DETECTION DEVICE, ORGANISM OBSERVATION METHOD, MICROSCOPE, ENDOSCOPE, AND OPTICAL TOMOGRAPHIC IMAGE GENERATION DEVICE - An optical inspection device | 01-16-2014 |
20140024946 | Apparatus, System and Method For Objectifying and Accessing Skin Conditions - A new method of rapidly objectifying and accessing an acne situation using numerical data and a scale measuring the severity of a particular skin condition and charted over time to allow easy identification of progress of the treatment therefor. The apparatus or software program which is also copyright protected, can be used to both numerically diagnose severity of a skin condition and to chart progress. The software apparatus can also be embeddable to other health related sites as an application to use on their site and a marketing tool. The application can be applied to anything visible on the skin such as bumps, dry patches, dark marks, cuts, scabs, scars or anything visible and useful for counting and objectifying the number or severity of the affliction. | 01-23-2014 |
20140024947 | ELECTRONICALLY SCANNED OPTICAL COHERENCE TOMOGRAPHY WITH FREQUENCY MODULATED SIGNALS - An improved Optical Coherence Domain Reflectometry (OCDR) system is provided. One embodiment of this OCDR system outputs a detector signal carrying image depth information on multiple modulation frequencies, where each modulation frequency corresponds to a different image depth. The image depth information from the detector signal may be resolved by tuning to the desired modulation frequency. Another system for imaging body tissue uses multiple frequency modulators such that the light beam does not travel from an optical fiber to free space. | 01-23-2014 |
20140024948 | FLUOROSCOPY APPARATUS - Provided is a fluoroscopy apparatus including a fluorescence imaging portion that acquires a fluorescence image of biological tissue; a return-light imaging portion that acquires a return-light image of the biological tissue; a fluorescence-region identifying portion that identifies a fluorescence region in the fluorescence image by using a processing condition specified from among a plurality of processing conditions; a superimposed-image generating portion that generates a superimposed image by superimposing the identified fluorescence region on a corresponding position in the return-light image; a treatment-information acquisition portion that acquires treatment-details information indicating the specifics of treatment to be applied to the biological tissue; and an image switching portion that specifies the processing condition to be used by the fluorescence-region identifying portion in accordance with the treatment-details information acquired by the treatment-information acquisition portion. | 01-23-2014 |
20140024949 | SURGICAL MICROSCOPY SYSTEM INCLUDING AN OCT SYSTEM - Receiver adapted for determining an estimation of interferences when receiving an OFDM signal made of packets, each packet comprising a first training field, a second training field, at least two header fields and data field, comprising:
| 01-23-2014 |
20140031697 | DIAGNOSTIC AND TREATMENT METHODS USING COHERENT ANTI-STOKES RAMAN SCATTERING (CARS)-BASED MICROENDOSCOPIC SYSTEM - An endoscopic microscopic system for collecting and processing a sequence of images in order to provide diagnosis and treatment is disclosed. Also disclosed are methods for making and using the system in a variety of diagnostic and therapeutic applications. | 01-30-2014 |
20140031698 | APPARATUS AND METHOD FOR SENSING BONE POSITION AND MOTION - This invention describes a novel photoplethysmographic system captures a joint shape change representing different positions of bones and tendons near the joint. At least one light source illuminates a joint interface and the light reflected from the joint location is captured by a photodiode sensor. Motions and positions of the bones surrounding the joint can be determined. One joint includes the knuckle. Finger lift-up motions, finger put-down motions, and finger bending events can be determined by monitoring a sensing area at the knuckle joint. | 01-30-2014 |
20140031699 | PHOTODYNAMIC DIAGNOSIS APPARATUS, PHOTODYNAMIC DIAGNOSIS METHOD AND DEVICE - There is provided a photodynamic diagnosis apparatus including a light source for generating a light pulse having a time width shorter than a fluorescence lifetime of a photosensitizer, and a detector for measuring a time change waveform of the fluorescence to the light pulse. | 01-30-2014 |
20140031700 | METHOD AND SYSTEM FOR MEASURING ANATOMICAL DIMENSIONS FROM A DIGITAL PHOTOGRAPH ON A MOBILE DEVICE - A mobile, hand-held communication device with a digital touch screen display and a camera for acquiring an image of the human body is programmed to function as a digital anthropometer. The user digitizes anatomical landmarks on the displayed image to quickly obtain linear measurements which are used with a known morphological relationship to make an anatomical prediction for clothing measurement, body composition and postural displacement with accuracy and without external equipment. | 01-30-2014 |
20140031701 | Otoscanner With 3D Imaging And Structure-From-Motion - Determination of structure-from-motion that includes a scanner body having mounted upon it a tracking illumination emitter and one or more tracking illumination sensors, the tracking illumination sensors disposed upon the scanner body so as to sense reflections of tracking illumination, the scanned object characterized by an object space defined by fixed positions of tracking targets; the scanner body having mounted within it an image sensor, the scanner body characterized by a scanner space, the image sensor coupled for data communications to a data processor and a computer memory, the image sensor and the processor capturing one or more images of the scanned object; and the data processor configured so that it determines by structure-from-motion, based upon the one or more captured images and tracked positions of the probe inferred from reflections of tracking illumination, the location in object space of a feature of the scanned object. | 01-30-2014 |
20140039322 | Diagnostic Device, Therapeutic Device, and Uses Thereof - Apparatus, method, computing devices, and computer programs related to photodiagnosis and photodynamic therapy, methods of use thereof, and a method for detecting abnormal tissue, are provided. | 02-06-2014 |
20140039323 | SYSTEM AND METHOD FOR DIAGNOSING AND TREATING DISEASE - A method and system for diagnosing and treating infection or disease, in which an individual takes a photograph of an infected or diseased area of a body using a camera connected to a microprocessor. The photograph is sent to a diagnosing center having a server with a second microprocessor and a database of photographs correlated with different diseases and infections. The second microprocessor scans the image received from the camera and compares it to the photographs in the database. If a match is found, the second microprocessor then notes the disease or bacteria corresponding to the matching photograph. The second microprocessor then searches an additional database correslated to the match, to further refine the diagnosis. The second microprocessor then searches the second database for a treatment corresponding to the identified disease or bacteria. Once a treatment is identified, information regarding this treatment is automatically sent to the individual's microprocessor. | 02-06-2014 |
20140046193 | Desktop-based opto-cognitive device and system for cognitive assessment - A highly portable desktop arrangement for cognitive testing which eliminates environmental effects is provided by a clam shell enclosure having a face mask on one face and housing a computer screen at an opposing wall, with accurate gaze direction measurement made by determining the position of the pupil if an individual whose face is pressed to the mask for eliminating head movement relative to the computer screen. | 02-13-2014 |
20140046194 | Coupler assembly for catheters - Coupler assemblies and methods are disclosed as the coupler assemblies may be used with a catheter. An exemplary coupler assembly includes a spherical linkage coupler for a catheter. The coupler comprises a first cylinder portion for connecting to a structure, and a second cylinder portion for connecting to a distal end of a body of the catheter. The coupler also comprises a spherical linkage including at least two link arms. Each of the two link arms are connected on one end to the first cylinder portion and on the other end to the second cylinder portion. The two link arms connect a portion of the structure to the distal end of the catheter and enable the structure to move relative to the distal end of the catheter in response to an external force exerted on the structure. | 02-13-2014 |
20140046195 | IN VIVO BIOLUMINESCENCE MONITORING APPARATUS - Apparatus for real-time in vivo bioluminescence monitoring in a conscious small animal, comprising a light-tight enclosure ( | 02-13-2014 |
20140052004 | ENDOSCOPIC CAMERA ILLUMINATION SYSTEM AND METHOD - An endoscopic camera system having an imaging device for taking images during an exposure period at a predetermined number of frames per second; an illumination system for providing light for the imaging device; and an illumination controller that supplies a drive current to the illumination system, the illumination controller altering the drive current to the illumination system so light is only provided for a portion of each image frame corresponding to the exposure period and for a second portion of each frame outside of the exposure period. | 02-20-2014 |
20140066782 | SYSTEM AND METHOD FOR DETERMINING A RESTING HEART RATE OF AN INDIVIDUAL - A system to determine a resting heart rate (HR) of an individual. The system may include a monitor that is configured to be operatively connected to a sensor that obtains physiological signals from an individual. The monitor is configured to receive the physiological signals from the sensor. The monitor may include a validation module that is configured to analyze the physiological signals to identify valid heart beats from the physiological signals. The monitor may also include a rate-determining module that is configured to determine an HR signal that is based on the valid heart beats. The HR signal includes a series of data points. The monitor may also include an analysis module that is configured to analyze the HR signal and identify baseline data points from the series of data points. The analysis module is configured to calculate the resting HR based on the baseline data points. | 03-06-2014 |
20140066783 | NOISE SHIELDING FOR A NONINVAISE DEVICE - A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector. | 03-06-2014 |
20140066784 | ENDOSCOPE AND IMAGE ACQUISITION METHOD - An endoscope configured to measure a specimen using a pattern projection image of the specimen on which a light and shade pattern of light is projected, the endoscope may include: an insertion unit; an image capturing unit installed at a tip section of the insertion unit and configured to acquire an image of the specimen; an illumination unit having a first light source configured to emit illumination light to illuminate an observation field of vision of the image capturing unit; a pattern projection unit having a second light source configured to emit projection light to project the light and shade pattern on the specimen; and a control unit configured to control an operation of acquiring the image by the image capturing unit, an operation of emitting the illumination light from the illumination unit, and an operation of emitting the projection light from the pattern projection unit. | 03-06-2014 |
20140073932 | METHODS AND SYSTEMS FOR DETERMINING SIGNAL-TO-NOISE INFORMATION FROM A PHYSIOLOGICAL SIGNAL - A physiological monitoring system may determine physiological information, such as physiological rate information, and other information, such as signal-to-noise information, from a physiological signal. The system may generate at least one difference signal based on the physiological signal and sort the at least one difference signal to generate at least one sorted difference signal. The system may analyze the at least one sorted difference signal to determine at least two values indicative of noise. The system may determine a value indicative of a signal-to-noise ratio based on the two or more values indicative of noise. | 03-13-2014 |
20140073933 | METHODS AND SYSTEMS FOR CONDITIONING PHYSIOLOGICAL INFORMATION BASED ON CALCULATED DIFFERENCES - A physiological monitoring system may determine physiological information, such as physiological rate information, from physiological data. The system may condition the physiological data to assist in the determination of the physiological information. The system may calculate differences based on the physiological data and identify differences that exceed a threshold. The calculated differences may, for example, be a derivative signal. The system may modify the physiological data based on the identified differences. The modification may include reducing, or otherwise limiting, some differences between adjacent values in the physiological data. | 03-13-2014 |
20140073934 | METHODS AND SYSTEMS FOR CONDITIONING PHYSIOLOGICAL INFORMATION BASED ON A SORTED DIFFERENCE SIGNAL - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may condition the physiological signal to assist in the determination of the physiological information. The system may generate a difference signal based on the physiological signal and sort the difference signal. The system may identify values in the sorted difference signal that exceed a threshold, and modify the physiological signal based on the identified values. The modification may include reducing, or otherwise limiting, some differences between adjacent values in the physiological signal. | 03-13-2014 |
20140073935 | METHODS AND SYSTEMS FOR CONDITIONING PHYSIOLOGICAL INFORMATION USING A NORMALIZATION TECHNIQUE - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may condition the physiological signal to assist in the determination of the physiological information. The system may generate a positive signal and a negative signal based on respective positive and negative values of the physiological signal. The system may filter the positive and negative signals, combine the filtered signals, and modify the physiological signal based on the combined signal. The physiological signal may be modified, for example, by subtracting the combined signal from the physiological signal. | 03-13-2014 |
20140073936 | METHODS AND SYSTEMS FOR CONDITIONING PHYSIOLOGICAL INFORMATION BASED ON A STABILITY FUNCTION - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may condition the physiological signal to assist in the determination of the physiological information. The system may generate a signal based on a stability function applied to the physiological signal. The stability function may include a Lyapunov function. The system may generate a difference signal based on the stability function, and modify the physiological signal based on the difference signal. The modification may include reducing, or otherwise limiting, some differences between adjacent values in the physiological signal, removing portions of the physiological signal, or other modifications. | 03-13-2014 |
20140073937 | METHODS AND SYSTEMS FOR CONDITIONING PHYSIOLOGICAL INFORMATION USING A NORMALIZATION TECHNIQUE - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may condition the physiological signal to assist in the determination of the physiological information. The system may generate absolute values of the physiological signal, filter the absolute values, and modify the physiological signal based on the filtered signal. The filtered signal may be shifted in amplitude prior to modifying the physiological signal. The modification may include dividing the physiological signal by the filtered signal to normalize the physiological signal. | 03-13-2014 |
20140073938 | METHODS AND SYSTEMS FOR DETERMINING PHYSIOLOGICAL INFORMATION BASED ON A CORRELATION SEQUENCE - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may generate a correlation sequence between two segments of the physiological signal at multiple correlation lag values. The system may compare the correlation sequence to a predetermined threshold, which may vary as a function of lag. Based on the comparison, the system may determine whether the correlation sequence value exceeds the threshold, and whether the correlation sequence value corresponds to a peak. The system may identify a lag value when the correlation sequence corresponding to the lag value exceeds the threshold and corresponds to a peak. The system may determine physiological rate information based on the identified lag value. | 03-13-2014 |
20140073939 | METHODS AND SYSTEMS FOR DETERMINING PHYSIOLOGICAL INFORMATION BASED ON A CORRELATION MATRIX - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may generate a lag matrix, which includes multiple segments of the physiological signal each having the same number of values. The system may generate a correlation matrix, which includes multiple correlation values, based on the lag matrix. The system may identify a peak in the correlation lag matrix, or a processed matrix derived thereof, and the corresponding lag value. The correlation matrix, or processed matrix thereof, may be rotated, averaged, or otherwise transformed by the system to identify the lag value. The system may determine physiological rate information based on the identified lag value. | 03-13-2014 |
20140073940 | METHODS AND SYSTEMS FOR DETERMINING PHYSIOLOGICAL INFORMATION BASED ON STATISTICAL REGRESSION ANALYSIS - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may select two segments of the physiological signal, shifted in time relative to one another by a lag value, and determine a correlation value between the two segments. The system may determine a metric based on the segments, and determine correlation information based on the correlation value and the metric. The metric may be indicative of how well the segments are correlated, providing additional information relative to the correlation value. Based on the metric, the system may modify the correlation value, determine a confidence value, or determine other information. The system may determine physiological rate information based on the correlation information. | 03-13-2014 |
20140073941 | METHODS AND SYSTEMS FOR QUALIFYING CALCULATED VALUES BASED ON STATE TRANSITIONS - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may receive a calculated value indicative of a physiological rate. Based on the value, the system may select pairs of values of the physiological signal that are particularly spaced. The system may determine a state for each pair of values. The state may correspond to a set of criteria such as, for example, equalities, inequalities, logical operators, or other criteria. The system may determine a number of state transitions based on the determined states, and qualify or disqualify the calculated value based on the number of state transitions. | 03-13-2014 |
20140073942 | METHODS AND SYSTEMS FOR QUALIFYING A CORRELATION LAG VALUE BASED ON SKEWNESS - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may determine a skew metric based on the physiological signal. The system may also determine a correlation lag value corresponding to a peak in a correlation sequence derived from the physiological signal. The system may qualify or disqualify the correlation lag value based on the skew metric. The system may, for example, compare the skew metric and the correlation lag value to a reference set of skew metric values and correlation lag values to determine whether to qualify or disqualify the correlation lag value. | 03-13-2014 |
20140073943 | METHODS AND SYSTEMS FOR QUALIFYING CALCULATED VALUES BASED ON MULTIPLE DIFFERENCE SIGNALS - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may receive a calculated value indicative of a physiological rate. The system may generate and sort multiple difference signals based on the physiological signal. The system may analyze a first sorted difference signal and a second sorted difference signal to determine at least one first metric, and analyze a third sorted difference signal and a fourth sorted difference signal to determine at least one second metric. The system may qualify or disqualify the calculated value based on the at least one first and second metrics. The segments used to generate the third and fourth sorted difference signals may, for example, be subsets of the segments used to generate the first and second sorted difference signals. | 03-13-2014 |
20140073944 | METHODS AND SYSTEMS FOR QUALIFYING A CORRELATION LAG VALUE BASED ON A CORRELATION VALUE AT A DIFFERENT LAG - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may generate a correlation sequence using two segments of the physiological signal. The system may determine a first correlation lag value that corresponds to a peak in the correlation sequence, and also determine a second correlation lag value equal to a fraction of the first correlation lag value. The fraction may be, for example, one half. The system may qualify or disqualify the correlation lag value based on the correlation value at the second lag value. The system may compare the correlation value at the second lag value to a threshold, to the correlation sequence at the first lag value, or both. | 03-13-2014 |
20140073945 | METHODS AND SYSTEMS FOR QUALIFYING A CALCULATED VALUE BASED ON DIFFERENTLY SIZED SORTED DIFFERENCE SIGNALS - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may receive a calculated value indicative of a period associated with a physiological rate. The system may generated a first sorted difference signal based on a segment of the physiological signal having a size corresponding to the period. The system may generate second and third sorted difference signals based on segments of the physiological signal having sizes corresponding to a fraction of the period and a multiple of the period. The system may analyze the first, second, and third sorted difference signals, and qualify or disqualify the calculated value based on the analysis. | 03-13-2014 |
20140073946 | METHODS AND SYSTEMS FOR DETERMINING AN ALGORITHM SETTING BASED ON A DIFFERENCE SIGNAL - A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may generate a first difference signal based on the physiological signal. The system may sort the first difference signal to generate a sorted difference signal. The system may generate a second difference signal based on the sorted difference signal. The system may determine an algorithm setting based on the second difference signal. The algorithm setting may, for example, affect the amount of filtering applied to the physiological signal. | 03-13-2014 |
20140073947 | METHODS AND SYSTEMS FOR DETERMINING NOISE INFORMATION FROM A PHYSIOLOGICAL SIGNAL - A physiological monitoring system may determine physiological information, such as physiological rate information, and other information, such as noise information, from a physiological signal. The system may generate a difference signal based on the physiological signal and sort the difference signal to generate a sorted difference signal. The system may identify one or more data points of the sorted difference signal as being associated with noise. For example, one or more end data points may be identified as being associated with noise based on a threshold. The system may determine a value indicative of noise based on the identified data points. | 03-13-2014 |
20140073948 | METHODS AND SYSTEMS FOR DETERMINING PHYSIOLOGICAL INFORMATION BASED ON FAILURE INFORMATION - A physiological monitoring system may process a physiological signal such a photoplethysmograph signal from a subject. The system may determine physiological information, such as a physiological rate, from the physiological signal. The system may use search techniques and qualification techniques to determine one or more initialization parameters. The initialization parameters may be used to calculate and qualify a physiological rate. The system may use signal conditioning to reduce noise in the physiological signal and to improve the determination of physiological information. The system may use qualification techniques to confirm determined physiological parameters. The system may also use autocorrelation techniques, cross-correlation techniques, fast start techniques, and/or reference waveforms when processing the physiological signal. | 03-13-2014 |
20140073949 | METHODS AND SYSTEMS FOR DETERMINING PHYSIOLOGICAL INFORMATION BASED ON FAILURE INFORMATION - A physiological monitoring system may process a physiological signal such a photoplethysmograph signal from a subject. The system may determine physiological information, such as a physiological rate, from the physiological signal. The system may use search techniques and qualification techniques to determine one or more initialization parameters. The initialization parameters may be used to calculate and qualify a physiological rate. The system may use signal conditioning to reduce noise in the physiological signal and to improve the determination of physiological information. The system may use qualification techniques to confirm determined physiological parameters. The system may also use autocorrelation techniques, cross-correlation techniques, fast start techniques, and/or reference waveforms when processing the physiological signal. | 03-13-2014 |
20140081146 | BONE MINERAL DENSITY MEASUREMENT APPARATUS AND METHOD - A support mechanism may maintain a middle phalanx in a fixed position relative to an imaging sensor/receptor during a bone mineral density (BMD) test. The mechanism may comprise a flat hand plate and a cover. The cover may be shaped so that it guides the finger towards the target area of the receptor. The cover may be raised slightly above the hand plate. A hand may be placed in the mechanism with the palm facing downwards, resting on the hand plate, and the middle finger raised and resting flat on an imaging receptor. A musculoskeletal response may ensure that the middle phalanx remains proximate the imaging receptor for the duration of the BMD Test. | 03-20-2014 |
20140081147 | ENDOSCOPE LIGHT SOURCE APPARATUS AND ENDOSCOPE SYSTEM - An endoscope light source apparatus includes a turret provided with a first optical filter and a second optical filter for transmitting an illuminating light, an instruction section in which an operation instruction of the turret is inputted, a drive section that drives the turret, a first detector that detects a position of the turret, a first detected portion for identifying a position of the first optical filter, a second detected portion for identifying a position of the second optical filter, a second detector that optically detects a position of the first or the second detected portion, and a turret control section that outputs a drive signal to the drive section to move the turret until the first or the second detected portion is detected by the second detector and stop the turret in response to the first or the second detected portion being detected. | 03-20-2014 |
20140081148 | HAIR TREATMENT DEVICE HAVING A LIGHT-BASED HAIR DETECTOR - A hair treatment device is provided comprising a light-based detector ( | 03-20-2014 |
20140088437 | SCREEN-BASED METHOD AND SYSTEM FOR SIZING AN ORAL APPLIANCE - An oral appliance is sized by obtaining a scaled image of a patient's dental arch. Dimensions of the arch are marked on a screen image, and the processor chooses an oral appliance having a best fit for a particular patient. | 03-27-2014 |
20140088438 | APPARATUS AND METHOD FOR FLUORESCENCE IMAGING AND TOMOGRAPHY USING SPATIALLY STRUCTURED ILLUMINATION - An imaging system for imaging an object. More specifically, an imaging system enabling depth sectioned fluorescence imaging in a turbid medium, such as human or animal tissue, to substantially minimize the excitation radiation from reaching the detection beam path. The imaging system includes an arrangement of the excitation radiation source wherein the optical axis of the source is inclined relative to the optical axis of the camera, the optical plane of the source and the optical plane of the object are subject to a Scheimpflug condition, and the angle of inclination of the source is selected such that the excitation radiation incident upon the object is reflected to minimize excitation radiation from reaching the detection beam path. | 03-27-2014 |
20140088439 | APPARATUSES FOR TREATING AND/OR DIAGNOSING MOTOR-RELATED NEUROLOGICAL CONDITIONS - Light therapy apparatuses are configured to expose a subject to light that is tailored to address and/or diagnose at least one motor-related neurological condition. Blue-green light and green light are useful for treating motor-related neurological conditions or their symptoms. Deep red light and near infrared radiation may facilitate the repair of retinal cells and/or neurons that may be responsible for motor-related neurological conditions. Amber, orange and red light enable the early diagnosis of motor-related neurological conditions. | 03-27-2014 |
20140088440 | Stereoscopic Plug-And-Play Dermatoscope And Web Interface - A system includes a device ( | 03-27-2014 |
20140107495 | Wearable Apparatus and Associated Methods - A wearable apparatus including a plurality of waveguides each configured to act as a conduit for light emitted from an illumination source to a photodetector via an interaction portion of the respective waveguide, the interaction portion of each waveguide configured to channel the light out of the respective waveguide to enable interaction of the light with the wearer's body and back into the respective waveguide to enable detection of the interacted light by the photodetector. | 04-17-2014 |
20140121529 | FINGER CLIP FOR PROSTATE GLOVE - Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a membrane can be sealed over a digit extension to form a closed volume. The closed volume can be inflated via an inflation tube, and a reference pattern can be disposed within the closed volume along with a measurement assembly. In use, a user can put on the glove, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the rectal wall, optical fibers in the measurement assembly can move relative to a reference pattern, and a controller can sense light reflected through the fibers from the reference pattern. The controller can calculate or estimate various attributes of the prostate based on the reflected light, such as the palpable surface width or volume. | 05-01-2014 |
20140121530 | APPARATUS AND METHOD FOR MEASURING GANGLION CELLS - An apparatus for measuring ganglion cells may include: a light generation unit configured to irradiate a first light signal polarized in a first direction and a second light signal polarized in a second direction perpendicular to the first direction to a subject; a reflected light processing unit configured to generate an amplification signal corresponding to an image of the subject using a first reflection signal, which is the first light signal reflected from the subject, and a second reflection signal, which is the second light signal reflected from the subject; and an image processing unit configured to measure ganglion cells in the subject using the amplification signal. The apparatus may be used to count the number of normal ganglion cells in the retina by measuring a phase difference of two lights polarized in different directions. The apparatus may also be used to monitor the progress of glaucoma. | 05-01-2014 |
20140121531 | DIAGNOSIS APPARATUS AND METHOD FOR ALZHEIMER'S DISEASE - Provided are apparatus and method for diagnosing Alzheimer's disease. The diagnosis apparatus may include a rod type image probe obtaining signals on a state of an olfactory epithelium tissue region, the rod type image probe including an end portion configured to be inserted into a nose and be in contact with the olfactory epithelium tissue region, a delivering element, by which the signals may be transmitted from the olfactory epithelium tissue region, the delivering element being connected to other end portion of the rod type image probe, and a signal processing unit converting the signals transmitted from the delivering element into digital signals. | 05-01-2014 |
20140121532 | SYSTEM AND METHOD FOR PREVENTION OF DIABETIC FOOT ULCERS - The present invention pertains to a device and method for monitoring of human feet including a transmissive sheet configured to bear at least 90 kg supported at a height of no more than 23 cm and having a foot image capture system below the sheet wherein an optical image sensor can capture a field of view including at least 250 cm | 05-01-2014 |
20140128742 | CANCER TISSUE DETECTION AND DIAGNOSIS USING LASER FLUORESCENCE - A laser diagnostic system includes multiple lasers providing incident light on a sample, the light modulated and cooperatively phased to stimulate red emissions from the sample; and a detector coupled to a spectrum analyzer, to detect both the incident light and the red emissions from the sample, and to provide a signal indicating detection of a pathology in the sample. | 05-08-2014 |
20140128743 | HIGH SENSITIVITY TEMPORAL FOCUSING WIDEFIELD MULTIPHOTON ENDOSCOPE CAPABLE OF DEEP IMAGING - An imaging system is provided that includes a pulsed light source providing pulsed light and is applicable to both microscopes and endoscopes. One or more optical elements with certain dispersive properties are positioned to receive the pulsed light and apply selective dispersive properties to shift the focal plane according to the user and to produce two photon (2p) wide field uniform illumination and 2p wide field structured illumination for the purpose of improving the optical axial resolution and rejection of background signal. An imaging element receives the signal arising from the 2p wide field uniform illumination and 2p wide field structured illumination and produces a respective 3D resolved image of a sample. | 05-08-2014 |
20140128744 | EFFICIENT MODULATED IMAGING - An apparatus for turbid sample measurement comprising a plurality of light sources for illuminating a turbid sample target area with non-spatial structured light, a projection system for illuminating the turbid sample target area with spatial structured light, a sensor for collecting light from the turbid sample target area, and a processor to analyze the data captured by the sensor to yield scattering and absorption coefficients of the turbid sample. A method comprises illuminating the sample with spatial structured light, collecting light reflected from the sample at a number of wavelengths, illuminating the sample with non-spatial structured light, collecting light reflected from the sample at a number of wavelengths, and combining the measurements of the collected light to obtain the optical properties of the sample and/or the concentration of absorbing or fluorescent molecules. The wavelengths of the spatial and non-spatial light sources are preferably different. | 05-08-2014 |
20140128745 | METHODS FOR PREVENTING AND TREATING MOTOR RELATED NEUROLOGICAL CONDITIONS - Methods for preventing or treating motor-related neurological conditions include using ocular light therapy in connection with a conventional therapy for a motor-related neurological condition, such as a drug regimen, to adjust levels of melatonin and/or dopamine in the body of a subject. The ocular light therapy may include elevated levels of blue-green light or green light (e.g., light within a wavelength range of 460 nm to 570 nm, 490 nm to 570 nm, about 520 nm to 570 nm, etc.). The ocular light therapy may also include reduced levels of amber, orange and/or red light. Methods for diagnosing motor-related neurological conditions include use of ocular light therapy to cause a subject to temporarily exhibit one or more symptoms of any motor-related neurological condition to which the subject is predisposed, or which the subject may already be experiencing. A temporary increase in such symptoms may be effected by ocular administration of light including increased amounts of amber, orange and/or red light. | 05-08-2014 |
20140128746 | INTERFEROMETRIC BIOMETRIC SENSING APPARATUS INCLUDING ADJUSTABLE COUPLING AND ASSOCIATED METHODS - A biological sensing apparatus comprises an excitation source configured to induce waves in a biological target, and an optical waveguide interferometer configured to sense the induced waves in the biological target. The optical waveguide interferometer comprises a probe segment having a probe segment end, and an adjustable coupler configured to permit setting a gap between the probe segment end and the biological target. A controller is coupled to the adjustable coupler and configured to set the gap between the probe segment end and the biological target. | 05-08-2014 |
20140142435 | RESPIRATORY FUNCTION ESTIMATION FROM A 2D MONOCULAR VIDEO - What is disclosed is a system and method for processing a video acquired using a 2D monocular video camera system to assess respiratory function of a subject of interest. In various embodiments hereof, respiration-related video signals are obtained from a temporal sequence of 3D surface maps that have been reconstructed based on an amount of distortion detected in a pattern placed over the subject's thoracic region (chest area) during video acquisition relative to known spatial characteristics of an undistorted reference pattern. Volume data and frequency information are obtained from the processed video signals to estimate chest volume and respiration rate. Other respiratory function estimations of the subject in the video can also be derived. The obtained estimations are communicated to a medical professional for assessment. The teachings hereof find their uses in settings where it is desirable to assess patient respiratory function in a non-contact, remote sensing environment. | 05-22-2014 |
20140148707 | METHOD FOR ESTIMATING A REFERENCE POSTURE - The invention relates to a method for estimating a reference posture of a subject with a view to taking measurements in order to determine the parameters for manufacturing a vision correction device, including, for a plurality of instances in which the head reaches a target reference posture from at least one deviated posture, the steps of: measuring the actual reference posture to thus obtain a plurality of sets of actual reference posture data, and storing said sets of data in a memory; and processing said sets of actual reference posture data using a digital processing unit in order to obtain an optimal reference posture. | 05-29-2014 |
20140148708 | SYSTEM AND METHOD FOR WOUND MANAGEMENT - A wound management reference object comprising a sheet of material of a known size including at least one colored segment, wherein the wound management reference object is configured to be positioned in close proximity to a wound, wherein an image can be captured of the wound management reference object and the wound, and wherein the image is used to evaluate the wound. | 05-29-2014 |
20140155756 | SYSTEM AND METHODS FOR HEALTH MONITORING OF ANONYMOUS ANIMALS IN LIVESTOCK GROUPS - Computerized system and method for livestock groups health monitoring comprising: a storage and computing unit storing at least one database; a plurality of data collecting units of different types, each type comprising at least one sensor, the data collecting unit types selected from the group consisting of acoustic sensors, vitality meters, ammonia sensors, visual sensors and scent sensors; first communication means for communicating operating commands from the storage and computing unit to each of the data collecting units and for communicating data from the data collecting units to the storage and computing unit ; and second communication means for communicating between the storage and computing unit and a user device. | 06-05-2014 |
20140155757 | PORTABLE EXOSCOPE IMAGING DEVICE FOR THE HUMAN BODY - The present invention relates to a portable CCD camera imaging device for the human body, comprising: a handle-shaped main body ( | 06-05-2014 |
20140163386 | Circuit for Heartbeat Detection and Beat Timing Extraction - A circuit and method for long term electrocardiogram (ECG) monitoring is implemented with the goal of reducing power consumption, battery size, and consequently device size. In one embodiment, the integrated circuit includes an amplifier cell having a plurality of input terminals and an output terminal; a QRS amplifier cell in communication with the output of the amplifier cell; a baseline amplifier cell in communication with the output of the amplifier cell; a comparator cell having a first input terminal in communication with the output terminal of the QRS amplifier cell; and a V | 06-12-2014 |
20140163387 | TRANSMITTED LIGHT DETECTION TYPE MEASUREMENT APPARATUS FOR SKIN AUTOFLUORESCENCE - The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator. | 06-12-2014 |
20140163388 | OPTICAL IMAGING APPARATUS - Measuring light emitted from a laser light source and split into four light rays through optical fibers is emitted into a space from emission units, and bent upward at a mirror. The measuring light passes through a window in the center of the sample stage and strikes a lower surface of the biological sample placed on the sample stage. A portion of fluorescence emitted through excitation by the measuring light passes through the window, is bent in an opposite direction from the measuring light by the mirror, and guided to a fluorescence camera. An objective lens, and a spectroscopic unit for separating visible wavelength components are horizontally arranged between the camera and the mirror. Although the projection of the measuring light and the detection of the fluorescence are performed perpendicularly to the biological sample, the optical components and elements are horizontally arranged. | 06-12-2014 |
20140163389 | IN VIVO DETECTION OF EOSINOPHILS - Snapshot spectral images viewing down the axis of the esophagus are processed to identify eosinophils. The snapshot images are based on fluorescence emitted in response to excitation optical radiation at two or more wavelengths. Ratio of spectral powers between snapshot images can be used in identification. In some examples, a relative abundance or density eosinophils is obtained, and processed to perform an in vivo assessment of tissue, such as esophageal tissue. | 06-12-2014 |
20140163390 | Implantable Biomedical Devices on Bioresorbable Substrates - Provided herein are implantable biomedical devices and methods of administering implantable biomedical devices, making implantable biomedical devices, and using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. | 06-12-2014 |
20140163391 | TUMOR SITE OR PARATHYROID GLAND IDENTIFICATION DEVICE AND METHOD - The present invention provides a device for identifying a tumor site in a subject, the device spectroscopically detecting fluorescence of protoporphyrins present in the tumor site,
| 06-12-2014 |
20140171806 | OPTICAL LESION ASSESSMENT - Medical apparatus includes a probe, having a distal segment configured for insertion into a body of a patient. The probe includes at least one optical sensing unit, which is disposed along the distal segment and includes first and second radiation sources, configured to emit optical radiation in different, respective, first and second wavelength bands toward tissue in the body in proximity to the distal segment. An optical sensor is configured to receive the optical radiation in the first and second wavelength bands that is scattered from the tissue and to output first and second electrical signals responsively to an intensity of the received optical radiation. | 06-19-2014 |
20140171807 | MEASUREMENT OF NEURAL FUNCTIONALITY USING PHASE SENSITIVE OPTICAL COHERENCE REFLECTOMETRY - Optical methods, devices, and systems for noninvasively detecting transient surface displacements in a neuron are disclosed. Methods, devices, and systems provided may employ a phase-sensitive optical low coherence reflectometer. In addition, surface displacements due to action potential propagation in neural tissues may be detected in some embodiments using back-reflected light. According to some embodiments, exogenous chemicals or reflect ion coatings are not required. Transient neural surface displacement of less then 1 nm in amplitude and 1 ms in duration may be detected and may be generally coincident with action potential arrival to the optical measurement site. The systems and methods may be used for noninvasive detection of various neuropathies such as retinal neuropathies. They may also be useful in detecting the effects of various pharmacological agents. | 06-19-2014 |
20140171808 | Optical Speculum - A system for direct imaging and diagnosing of abnormal cells in a target tissue includes a disposable optical speculum and an image acquisition system having the speculum assembled on and mechanically secured thereto. The image acquisition system is arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets. An image analysis and control unit in communication with the image acquisition system analyzes the data sets and applies algorithms to the data sets for diagnosing abnormal cells. | 06-19-2014 |
20140180129 | METHODS AND DEVICES SUITABLE FOR IMAGING BLOOD-CONTAINING TISSUE - Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm. | 06-26-2014 |
20140180130 | ANIMAL HANDLING ARRANGEMENT AND METHOD - A method and arrangement for determining a gut fill level of the rumen of an animal uses a three-dimensional camera and an image processing system. The three-dimensional camera is located in a station, wherein the animal is forced to stand essentially still during recording of the three-dimensional image. The three-dimensional camera is located on the left side of the animal at a height above the rumen triangle of the animal, longitudinally in essence in level with the rumen triangle, and is directed downwards towards the rumen triangle during the image recording. The image processing system automatically determines a depth and/or volume of a convexity or concavity of the rumen triangle, and determines the gut fill level of the rumen of the animal based on the determined depth and/or volume. | 06-26-2014 |
20140180131 | OPTICAL MEASUREMENT APPARATUS AND ENDOSCOPE SYSTEM - An endoscope system includes: an endoscope with a unit to be inserted into a subject and captures an inside image of the subject by an imaging unit provided in the unit to generate an image signal; an optical apparatus including a measurement probe to be inserted into the subject through the unit; an endoscope unit that switches between observation light of a plurality of wavelengths and outputs the observation light to observe a target object from the unit; a probe unit that outputs measurement light to measure characteristics of the target object via the measurement probe; a light unit that receives return light via the measurement probe, the return light caused by reflection and/or scattering of the measurement light on the target object; and a switching unit that switches a wavelength band of the measurement light to a different wavelength band from the observation light outputted by the endoscope unit. | 06-26-2014 |
20140180132 | SYSTEM AND METHOD FOR EXTRACTING PHYSIOLOGICAL INFORMATION FROM REMOTELY DETECTED ELECTROMAGNETIC RADIATION - The present invention relates to a system and a related method for extracting physiological information from remotely detected electromagnetic radiation. The system comprises an interface configured for receiving a data stream comprising image data representing an observed overall region comprising at least one subject of interest; a partitioning unit configured for defining a plurality of sub regions in the overall region; and a classifier configured for classifying the plurality of sub regions into at least one indicative type of region and at least one auxiliary type of region, wherein the at least one indicative type of region comprises at least one indicative region of interest at least partially representing the subject of interest. Preferably, the at least one auxiliary type of region comprises at least one reference region. More preferably, the system further comprises a data processor configured for processing at least one sub region classified as region of interest, thereby obtaining vital information. | 06-26-2014 |
20140187968 | SPECTRAL IMAGING WITH A COLOR WHEEL - A spectral imaging apparatus includes an image sensor positioned to capture images of a target, a rotating color wheel aligned with the image sensor, and a projector positioned to project overlay images onto the target. The color wheel can include one or more filter segments, each allowing light of a different range of wavelengths to pass. The color wheel can further include a blocking or opaque segment. A set of captured images of the different wavelengths can be processed to generate a false-color overlay image for projection onto the target. Processing of overlay images can be performed when the blocking or opaque segment is in front of the image sensor. The spectral imaging apparatus may be a multi-spectral imaging apparatus and made be used in the medical fields, such as for determining and indicating tissue oxygenation. Video rates can be achieved. | 07-03-2014 |
20140187969 | DROP GENERATING DEVICE - A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use. | 07-03-2014 |
20140194750 | OPTICAL ZOOM PROBE - Exemplary embodiments disclose an optical zoom probe including an aperture adjuster configured to adjust an aperture in which light transmitted by a light transmitter passes, a focus adjuster configured to focus the light passed through the aperture and adjust a focal length to an ultra-close location and a close location, and a filter which includes a center region in which incident light passes without change, and a filter region which surrounds the center region and increases a depth of focus (DOF) of light that is focused on the ultra-close location. | 07-10-2014 |
20140194751 | Scanned Laser Vein Contrast Enhancer Using One Laser for a Detection Mode and a Display Mode - The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head, The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like. | 07-10-2014 |
20140194752 | BIO-OPTICAL MEASUREMENT APPARATUS AND MEASUREMENT PROBE - A measurement probe is detachably connected to a bio-optical measurement apparatus which performs optical measurement on body tissue. The measurement probe includes two illumination fibers configured to irradiate the body tissue with low coherent light having a short spatial coherence length, and three or more light-receiving fibers configured to receive scattered light at multiple angles. The three or more light-receiving fibers are arranged on a perpendicular bisector of a line segment connecting centers of the two illumination fibers at a distal end surface of the measurement probe. | 07-10-2014 |
20140207003 | SYSTEMS AND METHODS FOR DETECTION OF DISEASE INCLUDING ORAL SCOPES AND AMBIENT LIGHT MANAGEMENT SYSTEMS (ALMS) - Methods and systems related to detecting disease, such as oral cancer, in a patient, using a viewing scope to investigate a patient's tissues. The systems and methods excite and detect fluorescence from the tissue. The fluorescence can then be evaluated, and the possibility of certain diseases such as cancer can be determined. The devices include an ambient light management system (ALMS, often referred to as a “vestibular device”) that manages background light in the health practitioner's office. This device can be used with scope systems for fluorescence based detection of abnormal tissue. | 07-24-2014 |
20140213909 | CONTROL-BASED INVERSION FOR ESTIMATING A BIOLOGICAL PARAMETER VECTOR FOR A BIOPHYSICS MODEL FROM DIFFUSED REFLECTANCE DATA - What is disclosed is a system and method for estimating a biological parameter vector for a biophysics model using reflectance measurements obtained from a reflectance-based spectral measurement system. The present method uses a semi-empirical biophysics model to describe skin properties and estimate reflectance spectra and reduces the dimensionality of the estimated and measured reflectance spectra using basis vectors for computational efficiency. A mixture of algorithms are employed to generate an initial set of parameters which, in turn, are further refined using an iterative control based technique in which the error between the parameters derived from the measured spectra are compared to the parameters calculated from the estimated spectra. These errors are then processed to generate a small delta to the initial set of parameters. The process is repeated until an error between the estimated virtual biological parameters and the measured virtual biological parameters falls to zero or is otherwise below a pre-defined threshold level. | 07-31-2014 |
20140236022 | SCANNING OPTICAL SYSTEMS - Scanning mechanisms that have application in confocal imaging use electromagnetic actuation to move elements in an optical system. An objective lens mounted to a flexure comprising a magnetic material is actuated in the axial direction by an electromagnet coil. An optical path may pass through the coil. Scanning in transverse directions may be provided using magnetically actuated flexible beams which move the tip of an optical fiber or other pinhole in one or more transverse directions. Actuators may be actuated using driving currents that include an AC component and a DC bias component. The scanning mechanisms may be miniaturized and may be constructed to provide real-time imaging. | 08-21-2014 |
20140236023 | Probe - A probe, such as a spectroscopic probe, for enabling a fluid or tissue sample to be tested in situ. The probe includes a conduit, such as a hypodermic needle, that can be inserted into a test subject and a wave coupling arranged to direct electromagnetic radiation, such as light, from an energy source to the sample and/or from the sample to a receiver for analysis. The receiver may comprise a Raman spectroscope. The probe may include a carriage that can be used to move at least some of the optical coupling towards and away from the insertion tip of the conduit. The probe may include a pressure modifier that can be used to draw fluid into or expel fluid from the conduit. | 08-21-2014 |
20140243684 | SYSTEM AND METHOD FOR CREATING, PROCESSING, AND DISPLAYING TOTAL BODY IMAGE - A system and method for creating and processing a total body image of a user from a plurality of user images. The system and method also includes enabling a medical professional/provider to access the user images and manage medical care for the user. | 08-28-2014 |
20140243685 | DERMATOSCOPE DEVICES - A dermatoscope has a generally circular viewing opening, a plurality of light sources including first and second groups of light sources arranged about the viewing opening, a first polarizer for polarizing light passing through the viewing opening, and a second polarizer for polarizing light emitted from the first group of light sources, wherein the first and second groups of light sources are arranged at different distances from a center of the viewing opening so that light from the second group of light sources is not polarized by the second polarizer. A further dermatoscope has a head portion including a generally circular viewing opening, and at least one light source arranged proximate to the viewing opening; and a body portion including an image capture device, wherein the head portion is pivotally attached to the body portion selectively allowing alignment of the center of the viewing opening with the center of the field of view of the image capture device. Yet a further dermatoscope has a generally circular viewing opening, a selectively extendable element that can be selectively extended coaxially with the viewing opening, and a contact element for contacting a surface to be viewed, the contact element being removably attachable to a distal end of the selectively extendable element. | 08-28-2014 |
20140243686 | METHOD AND APPARATUS FOR DETECTING DETERIORATION OF HEALTH STATUS - A system for early warning of health status decline includes at least one energy emitter configured to emit energy onto a field-of-view that contains an individual, and at least one energy sensor configured to capture reflected energy from within the field-of-view. A spatial measurement module calculates spatial measurements of a surface portion of the body of the individual when the individual is either stationary or moving about in real-time, based on data from the energy sensor. A comparator module detects deviations in measurements from baseline values indicative of a deterioration in health status of the individual. | 08-28-2014 |
20140257113 | OXYVU-1 HYPERSPECTRAL TISSUE OXYGENATION (HTO) MEASUREMENT SYSTEM - The invention is directed to a hyperspectral/multispectral system referred to as the OxyVu-1 system. The hyperspectral imaging technology performs spectral analysis at each point in a two-dimensional scanned area producing an image displaying information derived from the analysis. For the OxyVu-1 system, the spectral analytical methods determined in superficial tissues approximate values of oxygen saturation (HT-Sat), oxyhemoglobin levels (HT-Oxy), and deoxyhemoglobin levels (HT-Deoxy). The OxyVu-1 system displays the tissue oxygenation in a two-dimensional, color-coded image. | 09-11-2014 |
20140257114 | IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, AND COMPUTER-READABLE RECORDING DEVICE - An image processing apparatus includes an abnormal candidate region detection unit configured to detect an abnormal candidate region, as a candidate for an abnormal portion, from an intraluminal image obtained by capturing an image of an inside of a lumen of a subject, a tubular region detection unit configured to detect a tubular region from the intraluminal image, a connectivity determination unit configured to determine whether the abnormal candidate region and the tubular region are connected in a region of a color similar to that of the tubular region, and an abnormality determination unit configured to determine whether the abnormal candidate region is the abnormal portion, based on results of determination by the connectivity determination unit. | 09-11-2014 |
20140276092 | Method and Apparatus for Determining a Change in Tension of a Body Surface - A method of detecting a change in tension of a body surface during a medical procedure is provided. In some embodiments the method may be carried out without additional invasive devices or procedures being required. In one example the methodology is applied when using any type of body surface tensioning device. The tensioning device comprises fiducials that are visible to an image acquisition device. In another example of an embodiment of the current application, the methodology may be applied by attaching fiducials directly to the body surface. The relative motion of the fiducials relative to one another may be utilized to determine a change in body surface tension. | 09-18-2014 |
20140276093 | FULL-FIELD THREE-DIMENSIONAL SURFACE MEASUREMENT - Embodiments of the present invention may be used to perform measurement of surfaces, such as external and internal surfaces of the human body, in full-field and in 3-D. Embodiments of the present invention may include an electromagnetic radiation source, which may be configured to project electromagnetic radiation onto a surface. The electromagnetic radiation source may be configured to project the electromagnetic radiation in a pattern corresponding to a spatial signal modulation algorithm. The electromagnetic radiation source may also be configured to project the electromagnetic radiation at a frequency suitable for transmission through the media in which the radiation is projected. An image sensor may be configured to capture image data representing the projected pattern. An image-processing module may be configured to receive the captured image data from the image sensor and to calculate a full-field, 3-D representation of the surface using the captured image data and the spatial signal modulation algorithm. A display device may be configured to display the full-field, 3-D representation of the surface. | 09-18-2014 |
20140276094 | APPARATUS FOR OPTICAL SCANNING OF THE FOOT FOR ORTHOSIS - An apparatus is provided which provides proper compression of the soft tissue to simulate the joint positions, force applications and proprioceptive feedback of the natural foot in mid-stance gait and captures the topographical surface of the foot for orthosis production. The apparatus provides proper soft tissue compression while allowing an optical scanner to visualize the modified topographical skin surface. The apparatus includes an optically-transparent membrane to deform the soft tissue of the foot and an optical scanner configured to scan the foot through the membrane. | 09-18-2014 |
20140276095 | SYSTEM AND METHOD FOR ENHANCED GONIOMETRY - The invention comprises a computer-based system and method for enhanced goniometry using consumer grade data capture components coupled with software to monitor, track, and diagnose joint pain, injuries, and disorders. A video capture device is used to capture and display the movements of a patient in real time and stored in a database for review on a time-delayed basis. The patient movements are digitized by the video capture components and analyzed by the computer software program. By observing variations in joint movements and tracking the variations over time, a medical professional can monitor, evaluate, and diagnose a wide variety of joint diseases, injuries, and disorders. The medical professional can also prepare individualized treatment plans and monitor the results as the patient progresses in treatment and therapy. Additionally, the medical professional may use aggregated anonymous joint movement data to determine “best practices” for future patients, based on past results. | 09-18-2014 |
20140276096 | SYSTEMS AND METHODS FOR USE IN DIAGNOSING A MEDICAL CONDITION OF A PATIENT - Systems and method for use in diagnosing a medical condition of a patient are provided. The method includes providing medical condition information, receiving patient data relating to the medical condition information, comparing the received data to a baseline, and determining, by a computing device including a processor, a class of patient based on the received patient data. | 09-18-2014 |
20140276097 | SYSTEMS AND METHODS FOR OPTICAL MEASUREMENT FOR IN-SITU SURGICAL APPLICATIONS - A system and method is presented for performing optical measurements, including a light source configured to emit a light beam, a first pattern generator defining a first longitudinal axis and configured to project a first generated pattern, and a second pattern generator defining a second longitudinal axis and configured to project a second generated pattern. The first and second generated patterns have different angular divergency. The first pattern generator is a diffractive circle pattern generator, whereas the second pattern generator is a diffractive cross pattern generator. Adjustment of the first and second generated patterns with respect to each other cause the system to serve as an optical ruler for performing the optical measurements when the first and second generate patterns overlap or coincide with each other at certain points. | 09-18-2014 |
20140276098 | APPARATUS AND METHOD FOR DETERMINING VITAL SIGNS FROM A SUBJECT - An apparatus and a method for determining vital sign information from a subject are disclosed. The proposed apparatus comprises a detection unit for detecting radiation received from the subject in a field of view, a first determining unit for determining a first time dependent signal from the radiation received from the subject, an evaluation unit for deriving at least one parameter from the first time dependent signal, a selection unit for selecting an area in the field of view on the basis of the detected radiation and the at least one parameter, a second determining unit for determining a second time dependent signal from the radiation received from the selected area, and an analysis unit for analyzing the second time dependent signal and for determining the vital sign information on the basis of the analysis of the second time dependent signal. | 09-18-2014 |
20140276099 | DEVICE AND METHOD FOR DETERMINING VITAL SIGNS OF A SUBJECT - A device for determining a vital sign of a subject comprises an interface that receives a data stream derived from detected electromagnetic radiation reflected from a region of interest including a skin area of the subject, said data stream comprising a data signal per skin pixel area of one or more skin pixels for a plurality of skin pixel areas of said region of interest, a data signal representing the detected electromagnetic radiation reflected from the respective skin pixel area over time. An analyzer analyzes spatial and/or temporal properties of the skin area. A processor determines a vital sign information signal of the subject based on the data signals of skin pixel areas within the skin area, and a post-processor determines the desired vital sign from said vital sign information signal, wherein said determined spatial and/or temporal properties are used by the processor for determining the vital sign information signal and/or by the post-processor for determining the desired vital sign. | 09-18-2014 |
20140276100 | SYSTEM FOR MEASURING BREATH ANALYTES - A system is provided for sensing an analyte in a breath sample. The system includes a breath bag, a cartridge and a base. The breath bag contains the breath sample. The bag includes a mouthpiece fixedly disposed on the breath bag. The cartridge includes an interactant that reacts with the analyte and generates a change in an optical characteristic relative to a reference. The base includes a flow path, a breath bag receiver for detachably receiving and retaining the mouthpiece of the breath bag in fluid communication with the flow path, and a cartridge receiver that detachably receives and retains the cartridge in the base, such that the base engages the cartridge so that the interactant is in fluid communication with the flow path. The base further includes a flow handling system in fluid communication with the flow path, an optical subsystem for sensing the change in the optical characteristic, a processor operatively coupled to the flow handling system and the optical subsystem, and a user interface operatively coupled to the processor and comprising a start command. Upon user selection of the start command, the processor is configured to automatically regulate the flow handling system to move the breath sample in the flow path and to contact the breath sample and the interactant. Upon the occurrence of a predetermined process parameter, the processor is configured to automatically regulate the optical subsystem to sense the change in the optical characteristic, to correlate the sensing of the optical system with information about the analyte in the breath sample, and to output the information about the analyte in the breath sample to the user interface. Related methods also are provided. | 09-18-2014 |
20140276101 | MEDICAL DEVICE FOR DETECTING A TARGET AND RELATED METHODS OF USE - A medical device may include an elongate member having a proximal end, a distal end, and a lumen extending therebetween, wherein the elongate member may be configured for insertion into a patient. The medical device may also include a detection member configured to detect at least one of a location, geometry, or distance of a target relative to the distal end of the elongate member, the target being at least one of a stone, a foreign object, or a tissue within a body cavity. The detection member may include a transmitting element and a receiving element. | 09-18-2014 |
20140276102 | MEDICAL IMAGING DEVICE AND METHODS OF USE - Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed. | 09-18-2014 |
20140276103 | MEDICAL IMAGING DEVICE AND METHODS OF USE - Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed. | 09-18-2014 |
20140276104 | SYSTEM AND METHOD FOR NON-CONTACT MONITORING OF PHYSIOLOGICAL PARAMETERS - A system and method for monitoring one or more physiological parameters of a subject under free-living conditions is provided. The system includes a camera configured to capture and record a video sequence including at least one image frame of at least one region of interest (ROI) of the subject's body. A computer in signal communication with the camera to receive signals transmitted by the camera representative of the video sequence includes a processor configured to process the signals associated with the video sequence recorded by the camera and a display configured to display data associated with the signals. | 09-18-2014 |
20140276105 | SCANNING TECHNIQUES FOR PROBING AND MEASURING ANATOMICAL CAVITIES - Methods and apparatus, including computer program products, are provided for scanning an anatomical cavity. The method may include: selecting a scan path for obtaining data from sample areas inside the anatomical cavity, exciting a fluorescent material in an inflatable membrane that conforms to the anatomical cavity, measuring emitted light from the fluorescent material for each sample area, and characterizing the anatomical cavity. Characterizing may be based on at least one of a location or an intensity measurement for each sample area. The method may be executed using a scanning system that includes the inflatable membrane. | 09-18-2014 |
20140276106 | INTERACTIVE VIRTUAL CARE - An interactive virtual care system may include a user sensory module to acquire multi-modal user data related to user movement. A data analysis module may compare the multi-modal user data to predetermined historical user data and/or statistical norm data for users to identify an anomaly in the user movement. | 09-18-2014 |
20140276107 | PHOTODYNAMIC DIAGNOSIS - This invention relates to the diagnosis of abnormalities of the epithelial-lined surface of the esophagus and, in particular, to the use of esters of 5-aminolevulinic acid (5-ALA) in methods of photodynamic diagnosis (PDD) of Barrett's esophagus and in diagnostic methods which monitor the progression of the disease with high specificity. | 09-18-2014 |
20140288432 | INTRA-EXTRA ORAL SHOCK-SENSING AND INDICATING SYSTEMS AND OTHER SHOCK-SENSING AND INDICATING SYSTEMS - A mouth guard comprises a base member configured to fit inside the mouth of a user, and at least one shock-sensing and indicating device coupled to the base member. In one exemplary embodiment, the shock-sensing and indicating device is a passive shock-sensing and indicating device that detects a shock substantially along a selected axis with respect to the base member. In another exemplary embodiment, the at least one shock-sensing and indicating device detects a shock substantially along a plurality of selected axes with respect to the base member, each selected axis being substantially orthogonal from another selected axis. The shock-sensing and indicating devices can be configured to detect different levels of shock. In one exemplary embodiment, the shock-sensing and indicating device comprises a multi-component chemical-reaction system, such as a chemi-luminescent reaction system. | 09-25-2014 |
20140288433 | UV IMAGING FOR INTRAOPERATIVE TUMOR DELINEATION - A medical imaging system and method. A UV/visible camera uses a back illuminated silicon imaging detector to observe a surface of a brain of a subject in vivo during brain surgery for excision of a cancerous tumor. The detector can be a CCD detector or a CMOS detector. Under UV illumination, the camera can record images that can be processed to detect the location and extent of a cancerous tumor because the presence of auto-fluorescent NADH variations can be detected between normal and cancerous cells. The image data is processed in a general purpose programmable computer. In some instances, an image is also taken using visible light, and the identified cancerous region is displayed as an overlay on the visible image. | 09-25-2014 |
20140288434 | Optical Speculum - A system for direct imaging and diagnosing of abnormal cells in a target tissue includes a disposable optical speculum and an image acquisition system having the speculum assembled on and mechanically secured thereto. The image acquisition system is arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets. An image analysis and control unit in communication with the image acquisition system analyzes the data sets and applies algorithms to the data sets for diagnosing abnormal cells. | 09-25-2014 |
20140296718 | IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, INFORMATION PROCESSING PROGRAM, FLUORESCENCE OBSERVATION SYSTEM, AND FLUORESCENCE NAVIGATION SURGERY SYSTEM - An information processing apparatus includes a storage unit, a cutting-out unit, and a display controller. The storage unit is configured to store an image of fluorescence emitted from an observation target area of a living body in a recording medium as a fluorescence image of the observation target area, the image of fluorescence being captured with a first definition, the image of fluorescence being obtained by applying excitation light to the observation target area to which a fluorescent reagent is added in advance. The cutting-out unit is configured to cause a user to select at least a partial area of the fluorescence image and to cut out the selected area as a fluorescence image of a ROI area. The display controller is configured to cause a display unit to display the fluorescence image of a ROI area with a second definition that is lower than the first definition. | 10-02-2014 |
20140296719 | BIOMETRIC DEVICE, BIOMETRIC METHOD, PROGRAM, AND RECORDING MEDIUM - Provided is a biometric device including a light source unit configured to irradiate an organism with inspection light, a light-collection unit arranged facing a region on a surface of the organism and configured to spatially-integrally collect output light emitted from the region in accordance with the inspection light, and a light-reception unit configured to receive the collected output light. | 10-02-2014 |
20140303503 | APPARATUS AND METHOD FOR DETERMINING RESPIRATION SIGNALS FROM A SUBJECT - An apparatus and a method for determining respiration signals from a subject are disclosed. The apparatus comprises a receiving unit for receiving image data determined from the subject in a field of view, a processing unit for evaluating the image data, wherein the processing unit is adapted to determine a plurality of different alternating signals corresponding to vital sign information of the subject from a plurality of different areas of the field of view on the basis of movement pattern, and an evaluation unit for evaluating the different alternating signals and for determining a plurality of different respiration signals from the subject on the basis of the different alternating signals determined from the different areas of the field of view. | 10-09-2014 |
20140303504 | TISSUE AND CELLULAR IMAGING - Systems and methods for imaging ear tissue include: directing illumination radiation to pass through an intact biological structure and be incident on ear tissue that does not include an exogenous fluorophore, at a plurality of locations, the illumination radiation including a plurality of light pulses each having a temporal duration of 500 femtoseconds or less; for each one of the plurality of locations, using a detector to detect radiation emitted from the location that passes through the intact biological structure; and forming an image of the tissue based on the detected radiation at each of the plurality of locations, where the emitted radiation corresponds to endogenous two-photon fluorescence of the tissue. | 10-09-2014 |
20140309534 | PRESSURE PLATE DEVICE FOR ORTHOTIC SELECTION - A foot pressure measurement and foot length measurement device employs a plurality of pressure sensors and an optical foot length measurement system. The device also includes a computer that can perform an analysis of the foot pressure and length data to select an appropriate orthotic device. The foot measurement device may be integrated into a kiosk. Orthotic devices that have myriad configurations are also disclosed. | 10-16-2014 |
20140309535 | Apparatus for Mitigating Noise Affecting a Signal - A sensor overlies a body to aid in detecting unintended fluid accumulation. The sensor includes an absorbent that minimizes noise in detected electromagnetic radiation to make it easier to analyze a signal that is indicative of fluid accumulation in the body. | 10-16-2014 |
20140316278 | SYSTEM AND METHOD FOR SCALING A FLUID RESPONSIVENESS METRIC - The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient may include an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP metric. The monitor also may include a memory storing a relationship between the FRP metric and a pulse pressure variation (PPV) metric. The FRP metric is calculated based on a respiratory variation of the PPG signal and based on the relationship. | 10-23-2014 |
20140316279 | BIOLOGICAL OBSERVATION APPARATUS - Provided is a biological observation apparatus including irradiating portions that radiate illumination light onto biological tissue, an imaging portion that, of reflected light reflected at the biological tissue due to the illumination light radiated by the irradiating portions, captures reflected light in a wavelength band in which an absorption characteristic of β-carotene is greater than an absorption characteristic of hemoglobin, thus acquiring a reflected-light image, and a display portion that displays the reflected-light image acquired by the imaging portion. | 10-23-2014 |
20140316280 | DETECTION APPARATUS FOR DETERMINING A STATE OF TISSUE - The invention relates to a detection apparatus ( | 10-23-2014 |
20140323876 | SYSTEMS AND METHODS FOR DETERMINING FLUID RESPONSIVENESS IN THE PRESENCE OF GAIN CHANGES AND BASELINE CHANGES - Methods and systems are provided for determining fluid responsiveness based on physiological signals. The system may detect gain changes or excessive baseline modulations. In some embodiments, based on the detected gain changes or excessive baseline modulations, the system may ignore portions of physiological signals and determine a parameter indicative of fluid responsiveness based on a plurality of amplitudes determined from other portions of the physiological signals. In some embodiments, based on the detected gain changes or excessive baseline modulations, the system may determine fluid responsiveness, or refrain from determining fluid responsiveness. | 10-30-2014 |
20140330130 | Methods and systems for facilitating medical care - Mobile and/or computer based functionality to: (i) provide a secure method of communication between patients and physicians; (ii) provide reminders and/or alerts to patients in the form of mobile phone alerts, mobile phone alarms, email, text messages, etc.; (iii) offer calibrated photo taking using, e.g., shadow-overlay; (iv) utilize historical image data to identify complications or diagnose conditions; and (v) aggregate and present a composite of multiple photos (e.g., a time-lapse profile or gallery). | 11-06-2014 |
20140336516 | Localized Physiologic Status From Luminosity Around Fingertip Or Toe - Systems and methods are directed to generating and analyzing light. Spatial light response around a human fingertip in response to electrical stimulation is associated with the status of various body organs. A system that provides a particularized response indication based on spatial light response includes a camera, an electrical signal generator, a light source, a circuit, and a computer. The signal generator stimulates emission of light from the finger when the finger is at a position relative to the camera. The light source illuminates the finger at the position. The circuit activates the light source and the camera to obtain a first image of the finger at the position, activates the signal generator and the camera to obtain a second image of the emission of light from the finger at the position, determines a direction from the first image, determines a centroid from the second image, and determines a description of the second image in accordance with the direction and the centroid. The computer receives indicia of the description and provides the particularized response indication in accordance with the description, wherein the particularized response indication describes a status of various body organs. | 11-13-2014 |
20140343435 | METHODS AND DEVICES SUITABLE FOR IMAGING BLOOD-CONTAINING TISSUE - Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm. | 11-20-2014 |
20140350410 | METHOD AND APPARATUS FOR DETECTING LAMENESS IN LIVESTOCK - A device and method for detecting lameness in a standing animal uses at least one optical imaging device coupled to processing arrangement. The optical imaging device is arranged in a position to capture at least one image showing the lower portions of at least one leg of an animal and to forward the image to the processing arrangement, which, in turn, analyses the image to determine a condition of lameness when said at least one leg is held in a raised position on or above ground level. The system is particularly suited to detecting lameness in dairy animals and can be integrated in a milking or feeding stall or with an automatic or semi-automatic milking system. | 11-27-2014 |
20140358009 | System and Method for Collecting Eye-Movement Data - A system for creating an eye-movement record that is useful for diagnosing balance disorders of a patient includes a head-mounted unit having an indicator which generates head position signals. Also included is a computer/controller for progressing the patient through a sequence of predetermined head orientations. An imaging unit in the head-mounted unit is used to create an eye-movement record for each head orientation, and the records are then archived in a recorder. With instructions from the patient, a de-identified eye-movement record can be sent to selected regional specialists for further evaluation and possible treatment. | 12-04-2014 |
20140358010 | CLINICAL FITTING ASSISTANCE USING SOFTWARE ANALYSIS OF STIMULI - Embodiments of the present disclosure identify and alert a clinician to physiological cues thereby aiding the clinician in providing a better fitting of a medical prosthesis. Physiological data of a recipient of a medical prosthesis is analyzed to identify triggers during fitting or other types of adjustments to the prosthesis. A determination is then made as to whether the identified triggers correspond to a feedback event. If the triggers correspond to a feedback event, an alert containing information about the feedback event is generated and displayed or otherwise made available to the clinician. | 12-04-2014 |
20140358011 | SINGLE SHOT HIGH RESOLUTION CONJUNCTIVAL SMALL VESSEL PERFUSION METHOD FOR EVALUATING MICROVASCULATURE IN SYSTEMIC AND OCULAR VASCULAR DISEASES - A system and method for generating high-resolution, small vessel perfusion maps (nCPMs) of the ocular conjunctival microvasculature. Unlike current systems and methods, the present invention allows for the generation of nCPMs using only a single raw image obtained in a single image acquisition step. The method includes obtaining a single raw image of at least a portion of the microvasculature of the ocular conjunctiva. The raw image may be obtained using a digital camera and slit lamp. The red and blue color channels are removed from the raw image to create a color-adjusted image in which contrast between the microvasculature and the sclera is enhanced. The color-adjusted image is then inverted and saved as a grayscale inverted image. The grayscale inverted image may be skeletonized. The grayscale image and/or the skeletonized image may be quantitatively analyzed. | 12-04-2014 |
20140364744 | APPARATUS, INTERFACE UNIT, SUCTION RING AND METHOD TO MONITOR CORNEAL TISSUE - An apparatus and a method for cutting or ablating corneal tissue of an eye provide for detection of electromagnetic radiation exiting the eye. A detector is provided and coupled to a computer controlling the cutting or ablating laser radiation so that a two- or three-dimensional image of radiation exiting the eye can be generated. | 12-11-2014 |
20140364745 | MULTI-SPECTRAL TISSUE IMAGING - Apparatus and methods are disclosed for multi-spectral imaging of tissue to obtain information about the distribution of fluorophores and chromophores in the tissue. Using specific spectral bands for illumination and specific spectral bands for detection, the signal-to-noise ratio and information related to the distribution of specific fluorophores is enhanced as compared to UV photography, which uses a single RGB image. Furthermore, the chromophore distribution information derived from the multi-spectral absorption images can be used to correct the fluorescence measurements. The combined fluorescence, absorption, and broadband reflectance data can be analyzed for disease diagnosis and skin feature detection. | 12-11-2014 |
20140371599 | MOTION ANALYSIS FOR BEHAVIOR IDENTIFICATION - Devices, systems, and techniques for analyzing video information to objectively identify patient behavior are disclosed. A system may analyze obtained video information of patient motion during a period of time to track one or more anatomical regions through a plurality of frames of the video information and calculate one or more movement parameters of the one or more anatomical regions. The system may also compare the one or more movement parameters to respective criteria for each of a plurality of predetermined patient behaviors and identify the patient behaviors that occurred during the period of time. In some examples, a device may control therapy delivery according to the identified patient behaviors and/or sensed parameters previously calibrated based on the identified patient behaviors. | 12-18-2014 |
20140371600 | Apparatus For Meausring In-Vivo Mechanical Properties of Biological Tissues - An apparatus and method for measuring mechanical properties of tissue has a stereo optical surgical microscope with at least one objective lens and at least two digital cameras such that paired images obtained from the digital cameras form stereo pairs, and a digital image processing system adapted to determine surface topography of tissue from the stereo pairs of images and a resulting surface displacement map as a result from indentation. The apparatus has an one indenter; and mechanical modeling routines stored in memory of the image processing system, the mechanical modeling routines capable of constructing computer models of mechanical properties of tissue, and fitting parameters of the computer model to observed surface displacement maps generated by coregistering surface topography of tissue with and without the indenter positioned on the tissue. In an embodiment, fitted parameters of the computer model are displayed and used to adjust a surgical plan. An apparatus and method for measuring mechanical properties of tissue has a stereo optical surgical microscope with at least one objective lens and at least two digital cameras such that paired images obtained from the digital cameras form stereo pairs, and a digital image processing system adapted to determine surface topography of tissue from the stereo pairs of images and a resulting surface displacement map as a result from indentation. The apparatus has an one indenter; and mechanical modeling routines stored in memory of the image processing system, the mechanical modeling routines capable of constructing computer models of mechanical properties of tissue, and fitting parameters of the computer model to observed surface displacement maps generated by coregistering surface topography of tissue with and without the indenter positioned on the tissue. In an embodiment, fitted parameters of the computer model are displayed and used to adjust a surgical plan. | 12-18-2014 |
20140371601 | Systems and Methods for Detecting Physiological Information of a User - Described herein are systems and methods for improving the reliability and accuracy of wearable physiological monitoring devices. A wearable monitoring device may comprise an inner surface configured for at least partial contact with a targeted tissue region of a person. The inner surface may comprise one or more outwardly projecting raised regions. The monitoring device may further comprise a physiological sensor, one or more components of which may be located at or near a raised region of the inner surface. In this manner, sufficient contact between the targeted tissue region and the inner surface, as well as proper placement of the one or more components of the sensor relative to the targeted tissue region, may be achieved. The accuracy and reliability of the monitoring device may also be less susceptible to the effects of ambient light and/or the movements of the user. | 12-18-2014 |
20140378843 | Method And Apparatus For Quantitative Hyperspectral Fluorescence And Reflectance Imaging For Surgical Guidance - An imaging system includes an illumination device for illuminating a target. A surgical microscope receives light from the target, the surgical microscope comprising at least one optical output port at which at least a portion of the received light is provided as an output from the surgical microscope. A tunable filter receives the portion of the received light provided as the output from the surgical microscope, the tunable filter being tunable to pass a filtered portion of the received light, the filtered portion of the received light having a plurality of wavelengths selected by the tunable filter and provided as output from the tunable filter. A high-resolution, broad-bandwidth electronic camera receives the light of a plurality of wavelengths selected by the tunable filter, the electronic camera converting the light of a plurality of wavelengths selected by the tunable filter to a plurality of electrical signals. A processor processes the plurality of electrical signals to form an image of the target. | 12-25-2014 |
20140378844 | Systems and Methods for Optical Sensor Arrangements - Described herein are systems and methods for mounting optical sensors in a physiological monitoring device worn by a user to sense, measure, communicate, and/or display physiological information. The monitoring devices may be embodied as, for example, a fitness band, a bracelet, a watch, or some other wearable device such as an activity tracker, a health, wellness, or sleep monitor, or an athletic training device. The device may comprise one or more light sources and optical detectors. Optical lenses may be mounted in a face of the device for partially receiving or containing the light sources and optical detectors. The devices and methods described herein may optically isolate the light source(s) from the optical detector(s) to ensure the accurate and reliable detection and measurement of physiological information. | 12-25-2014 |
20150011893 | EVALUATION OF SKIN LESIONS BY RAMAN SPECTROSCOPY - A Raman spectrometer system provides a tool for discriminating between different tissue pathologies. The tool may provide discrimination indicators for a plurality of different pairs of tissue pathologies. Improved sensitivity and specificity are achieved by basing discriminations on appropriate ranges within a Raman spectrum. | 01-08-2015 |
20150011894 | SYSTEM FOR AND METHOD OF QUANTIFYING ON-BODY PALPITATION FOR IMPROVED MEDICAL DIAGNOSIS - A haptic sensor for performing palpation includes a deformable membrane having a reflective surface, a light source, a camera, and a processor. When the sensor is pressed against an object on a body, the deformable membrane deforms to contour to the shape of the object, light is reflected off the reflective surface, and captured by a camera. The reflected light is processed to reconstruct a 3-D image of the object. The rendered image can show abnormalities such as cysts, tumors, or other abnormalities, as well as arterial pressure pulses. In different embodiments, the sensor illuminates the deformed membrane from multiple directions, using shape-from-shading or grayscale mapping, or using video streams to provide more accurate images. The sensor is able to be included as part of a mobile device, such as a mobile phone, thereby making it compact and portable. | 01-08-2015 |
20150011895 | Methods and Systems for Determining Mechanical Properties of a Tissue - Systems and methods for determining mechanical properties of a biological tissue in a subject are provided. A low coherence optical interferometer detects waves generated from a surface of a tissue in a subject. The waves are generated from elastographic deformation of the tissue induced by an impulse stimulation. Phase velocities can then be determined from the waves, and elastographic properties from the phase velocities, including an elasticity value for a portion of the surface of the tissue. | 01-08-2015 |
20150011896 | VESSEL IMAGING SYSTEM AND METHOD - A method for locating a vessel, the method comprising illuminating at least a portion of the vessel with a background light having a substantially high susceptibility to absorption by particles in said portion of the vessel; detecting backscattered light from said illuminated portion of the vessel; reproducing an image from said backscattered light; and identifying dark regions within said reproduced image. | 01-08-2015 |
20150011897 | ILLUMINATION DEVICE FOR TUMOR DETECTION AND ILLUMINATION DEVICE FOR EXAMINATIONS - The present invention is an illumination device for tumor detection, which improves the visibility of a tumor in which a fluorescent substance is accumulated, and emits excitation light for the fluorescent substance accumulated in the tumor, and the illumination device for tumor detection is provided with: a light emitting diode that emits light of which a wavelength range substantially coincides with an excitation wavelength range for the fluorescent substance; and a blocking part that is provided on a light emission side of the light emitting diode, and blocks the same wavelength as at least a part of the excitation wavelength range for the fluorescent substance. | 01-08-2015 |
20150018692 | BI-PHASIC PAIRED PULSE TRANSCRANIAL MAGNETIC STIMULATION - It is an aspect of the present invention to provide a method for recording a response to Transcranial Magnetic Stimulation (TMS) utilizing a bi-phasic double pulse pair from a TMS coil device to stimulate a subject wherein the second pulse has a lower amplitude compared to the first pulse in the bi-phasic double pulse pair. Significant advantages are achieved using bi-phasic double pulse pairs, particularly where the second pulse in a pair has an intensity lower than the first. Obtaining measurements is simpler and more accurate as the number and intensity of stimulation can be reduced compared to standard single pulse stimulation. | 01-15-2015 |
20150025391 | Tissue Fluorescence Monitor With Ambient Light Rejection - Fluorescent markers used to identify a tissue may be imaged in a bright environment by synchronizing the imaging process with rapidly switched ambient lighting so that imaging occurs in phase with a switching off of the ambient lighting. In this way, valuable fluorescent imaging may be performed in an environment that appears to be brightly illuminated, for example in the area of a surgical suite. | 01-22-2015 |
20150025392 | EFFICIENT 3-D TELESTRATION FOR LOCAL AND REMOTE ROBOTIC PROCTORING - An apparatus is configured to show telestration in 3-D to a surgeon in real time. A proctor is shown one side of a stereo image pair, such that the proctor can draw a telestration line on the one side with an input device. Points of interest are identified for matching to the other side of the stereo image pair. In response to the identified points of interest, regions and features are identified and used to match the points of interest to the other side. Regions can be used to match the points of interest. Features of the first image can be matched to the second image and used to match the points of interest to the second image, for example when the confidence scores for the regions are below a threshold value. Constraints can be used to evaluate the matched points of interest, for example by excluding bad points. | 01-22-2015 |
20150032008 | METHOD AND APPARATUS FOR TISSUE DISEASE DIAGNOSIS - A tissue diagnosis apparatus constituted of: a broad band light source arranged to irradiate a target area with broad band light; a narrow band light source arranged to irradiate the target area with narrow band light; at least one light sensor arranged to: sense the broad and narrow band light after interaction with the target area; a color sensor arranged to sense the broad band light after interaction with the target area; and a housing, the broad band light source, narrow band light source, light sensor and color sensor situated within the housing, wherein a control circuitry is arranged to: determine the image abnormality of the sensed broad band light, the spatial scattering of the sensed narrow band light and the chromatic impact of the interaction of the broad band light with the target area; and output a signal responsive to the identified image abnormality, spatial scattering and chromatic impact. | 01-29-2015 |
20150032009 | Wearable Light-Guiding Devices For Physiological Monitoring - A monitoring device configured to be attached to the body of a subject includes an outer layer and an inner layer secured together. The inner layer includes light transmissive material and has inner and outer surfaces. A base is secured to at least one of the outer and inner layers and includes an optical emitter and optical detector. A layer of cladding material is positioned near the outer surface of the inner layer, and at least one window is formed in the layer of cladding material that serves as a light-guiding interface to the body of the subject. The light transmissive material delivers light from the optical emitter to the body of the subject along a first direction and collects light from the body of the subject and delivers the collected light in a second direction to the optical detector. The first and second directions are substantially parallel. | 01-29-2015 |
20150038849 | Methods for Reducing One or More Symptoms of Temporomandibular Joint Disorder - An in-ear device configured to help a subject manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device. Also disclosed is a method of helping manage at least one symptom associated with TMD by providing an in-ear device for wear while the subject is awake and providing a bite guard for wear at night while the subject is sleeping. | 02-05-2015 |
20150038850 | In-Ear Device With at Least One Sensor - An in-ear device with at least one sensor configured to generate a signal to help a subject manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device. | 02-05-2015 |
20150038851 | MEIBOMIAN GLAND DYSFUNCTION - Provided herein are methods of diagnosing meibomian gland dysfunction (MGD), determining the severity of meibomian gland dysfunction in a subject, evaluating efficacy of treatment of MGD in a subject, selecting a subject for treatment of MGD, and selecting a subject for participation in a clinical study. | 02-05-2015 |
20150045676 | Head Positioning Device - A head positioning device for use in radio therapy is described for positioning a patient's head. The head positioning device comprises a head plate for supporting a patient's head; a base plate for connection to a mechanical couch; and a head plate adjustment assembly connecting the head plate to the base plate wherein the head plate adjustment assembly is arranged to vary the relative pitch, yaw and roll of the head plate relative to the base plate. The head positioning device is arranged to be attached to a mechanical couch with the head plate and the head plate adjustment assembly cantilevered off the end of the couch and the head plate adjustment assembly suspended beneath the head plate and the base plate. | 02-12-2015 |
20150051497 | SYSTEM FOR MULTISPECTRAL IMAGING OF FLUORESCENCE - The present invention is a confocal scanning system for the multispectral imaging of fluorescence from a tissue sample based on the mapping of the spectral components of the fluorescence into the time domain using coated fiber tips disposed on multimode optical fibers. A fiber grating spectrometer based on two serial arrays of coated fiber tips disposed on multi-mode fiber, and delay lines between them provide spectral slices of the florescence. The coated fiber tips are arranged such that the shortest wavelength spectral components are reflected first and the longest wavelength components last. Fiber-based delay lines delay the reflections from each successive fiber tip such that they are uniformly separated in time, and in the order of its spectral wavelength number. The spectral bins are used to colorize the images to show the presence of abnormal tissue at cellular spatial resolution. A second scan with increased laser flux can destroy the diseased tissue revealed by the first scan. | 02-19-2015 |
20150057549 | LIVE BEING OPTICAL ANALYSIS SYSTEM AND APPROACH - Analysis of live beings is facilitated. According to an example embodiment of the present invention, a light-directing arrangement such as an endoscope is mounted to a live being. Optics in the light-directing arrangement are implemented to pass source light (e.g., laser excitation light) into the live being, and to pass light from the live being for detection thereof. The light from the live being may include, for example, photons emitted in response to the laser excitation light (i.e., fluoresced). The detected light is then used to detect a characteristic of the live being. | 02-26-2015 |
20150057550 | ROBOTIC IMAGING SYSTEM - A robotic imaging system has at least one robotic imaging arm that includes a free-space optics subsystem. The free-space optics is capable of conveying an excitation light signal through the robotic imaging arm to an optical end effector at the distal end thereof while maintaining coaxial alignment between the optical axis and the robotic skeleton. The free-space optics is also capable of maintaining linear polarization of the light signal. | 02-26-2015 |
20150073283 | METHOD AND APPARATUS FOR MONITORING MOVEMENT AND BREATHING OF MULTIPLE SUBJECTS IN A COMMON BED - The invention relates to methods and apparatus for monitoring movement and breathing of two or more subjects occupying common bedding. Particularly, the invention relates to a method for monitoring movement of subjects located in a common bedding, the method comprising the steps of:—imaging the bedding by an optical sensor;—performing a motion estimation by producing motion vectors indicating the local displacement of corresponding image blocks between consecutive images, or images that are several frames apart, received from said optical sensor;—calculating motion clusters by measuring spatial and temporal correlations of the motion vectors;—segmenting the calculated motion clusters by assignment of each motion cluster to a corresponding subject, wherein the assignment of the motion clusters to the corresponding subject is based on the spatial and/or temporal similarity of the motion clusters among each other and on previous segmentation results. | 03-12-2015 |
20150080738 | APPARATUS, METHOD, AND COMPUTER-ACCESSIBLE MEDIUM FOR DETERMINING ANTIGEN IMMUNOREACTIVITY IN TISSUE - Exemplary configurations can be provided which can be structured to be included and/or inserted in an internal anatomical structure. For example, the configuration(s) can have at least one first arrangement which can include at least one substance that, when applied to at least one section of the internal anatomical structure, has a potential to induce an inflammatory response in the section(s). The configuration(s) can also have at least one second (e.g., microscopy) arrangement which can be configured to receive information from the section(s), and determine whether the inflammatory response has occurred therein. | 03-19-2015 |
20150080739 | OPTICAL MEASURING SYSTEM - An optical measuring system comprises a control device and an optical meter. The optical meter comprises a first case, a first controller for controlling light emitters for irradiating a patient with light and light receivers for receiving light from the patient to obtain measurement data regarding a cerebral activity, and a first transmitter and receiver for transmitting the measurement data to the control device. The control device comprises a second case removably attached to the first case, a display and input device on a surface of the second case, a second transmitter and receiver for receiving the measurement data from the optical meter, and a second controller for controlling the display and input device to display the measurement data from the optical meter. The second case can be attached on a top face of the first case when the first case is placed on a table. | 03-19-2015 |
20150080740 | OPTICAL TARGETING AND VISUALIZATION OF TRAJECTORIES - Enhanced targeting systems and methods may be used to visualize trajectories for surgical instruments. Such a targeting system may have a fixture that can be secured at a predetermined location relative to a patient, a first light source attached to the fixture, and a second light source attached to the fixture. The first light source may project first light along a first plane, and the second light source may project second light along a second plane nonparallel to the first plane. At an intersection of the first and second planes, the first light and the second light may cooperate to produce a targeting line that indicates the desired trajectory. A controller may be connected to first and second sets of motors to orient the first and second light sources, respectively. The targeting line may be projected on a visualization aid that guides the surgical instrument along the trajectory. | 03-19-2015 |
20150080741 | LIGHT-GUIDING DEVICES AND MONITORING DEVICES INCORPORATING SAME - A monitoring device configured to be attached to the ear of a person includes a base, an earbud housing extending outwardly from the base that is configured to be positioned within an ear of a subject, and a cover surrounding the earbud housing. The base includes a speaker, an optical emitter, and an optical detector. The cover includes light transmissive material that is in optical communication with the optical emitter and the optical detector and serves as a light guide to deliver light from the optical emitter into the ear canal of the subject wearing the device at one or more predetermined locations and to collect light external to the earbud housing and deliver the collected light to the optical detector. | 03-19-2015 |
20150087998 | Cooling Of A Medical Instrument - A medical instrument includes a hermetically tight sheath, a heat source, a surface area thermally coupled to the heat source, a rotor arranged outside the hermetically tight sheath and serving to generate a flow of fluid at the surface, a magnet at the rotor, and means for generating a variable magnetic field in order to move the rotor. The means for generating a variable magnetic field is arranged inside the hermetically tight sheath. | 03-26-2015 |
20150087999 | SINGLE SCAN MULTI-PROCEDURE IMAGING - A method includes receiving a signal indicative of a single user selected imaging protocol for scanning a patient. The imaging protocol includes parameters for two or more of a bone mineral density, a fat composition, or an aortic calcium imaging procedures. The method further includes performing a single scan of the patient using the single user selected protocol. The method further includes generating a single set of image data for the two or more of a bone mineral density, a fat composition, or an aortic calcium imaging procedures. | 03-26-2015 |
20150088000 | METHOD FOR MANUFACTURING OPTICAL DEVICE, OPTICAL DEVICE, AND BIOLOGICAL INFORMATION DETECTOR - A biological information detector includes a substrate, a light-emitting element, a light-receiving element, and a bonding pad. The light-emitting element has a thickness of 20 μm to 1000 μm. The light-receiving element has a thickness of 20 μm to 1000 μm. The bonding pad is disposed at a position that overlaps the light-emitting element and that is displaced relative to a center of the light-emitting element in a plan view as viewed in a perpendicular direction perpendicular to an emitting surface of the light-emitting element. A wavelength of light emitted by the light-emitting element is within a range of 470 nm to 600 nm. | 03-26-2015 |
20150094598 | DEVICE FOR MONITORING BLOOD LEAKAGE FROM WOUNDS - A device for monitoring a skin surface for leakage of blood at, for example, a wound or a vascular access. The device comprises a patient unit, a connection unit and a monitor unit. The patient unit comprises a patch, including an adhesive layer to be attached to the skin surface of the patient. The adhesive layer is arranged to attach the patch to the skin so that a predetermined removal force, such as 30N, is required for removing the patch from the skin surface. A patient optical fiber is arranged at the patch and has a proximal end for connection to the connection unit. A patient connector is arranged at the distal end of a connection optical fiber. The connector has an opening passing through the connector, whereby the connection optical fiber is arranged in one end of the opening. The patient optical fiber may be inserted in the other end of the opening so that the proximal end of the patient optical fiber is arranged in register with the distal end of the connection optical fiber in order to transmit light between the optical fibers. A spring is arranged in the connector for exerting a force at the patient optical fiber at a side surface thereof for preventing unintentional withdrawal of the patient optical fiber. However, when the withdrawal force is larger than the removal force of the patch, the patient optical fiber is withdrawn from the connector. Thus, the patch is not removed from the skin even when a large force is exerted on the optical fibers. | 04-02-2015 |
20150094599 | VARIFOCAL LENS, OPTICAL SCANNING PROBE INCLUDING THE VARIFOCAL LENS, AND MEDICAL APPARATUS INCLUDING THE OPTICAL SCANNING PROBE - A varifocal-type optical scanning probe including an optical fiber scanner and a varifocal lens is provided. The varifocal lens includes: a first membrane lens comprising a first lens surface with a variable curvature and a first pressure surface configured to induce a curvature variation of the first lens surface; a second membrane lens including a second lens surface with a variable curvature and a second pressure surface configured to induce a curvature variation of the second lens surface; a first pressure member disposed to apply a pressure to the first pressure surface; a second pressure member disposed to apply a pressure to the second pressure surface; and a motor configured to transmit a driving force to at least one of the first pressure member and the second pressure member. | 04-02-2015 |
20150094600 | System And Method For Imaging Myelin - The present invention provides a system and method for detecting myelin and myelin-related disease. For example, the invention is based upon the finding that the combined reflectance of an administered multi-wavelength laser light specifically detects myelinated fibers. It is demonstrated herein that the present system and method effectively detects myelin, myelin defects, and myelin pathology. | 04-02-2015 |
20150099981 | Tubular Light Guide - Disclosed are various embodiments for scanning a cavity surface using a tubular element comprising an inner wall and an outer wall. The tubular element may be designed to guide and approximately collimate light received from a light source from the first end of the tubular element to the second end of the tubular element. The light may be guided between the inner wall and the outer wall of the tubular element. The light may be projected from the tubular element onto a cone mirror fixed at the second end of the tubular element. The cone mirror may be designed to radially reflect the light guided to the second end of the tubular element when the light is within a predefined wavelength range. | 04-09-2015 |
20150099982 | SENSOR AND FASTENER - A sensor which is adapted to attach to a head of a subject includes a first fastener that includes a first end portion and a second end portion and extends into an arc-shape, a first coupling portion that is disposed on an inner circumference side of the first fastener, a second fastener that has a first through hole and a second through hole, a second coupling portion that is disposed on a first side of the second fastener, and attachable to and detachable from the first coupling portion, a light emitter that is disposed on the first side of the second fastener, and opposed to the first through hole, and a light detector that is disposed on the first side of the second fastener, and opposed to the second through hole. | 04-09-2015 |
20150105667 | ILLUMINATOR FOR PHOTODYNAMIC THERAPY - An apparatus and method for photodynamic therapy or photodynamic diagnosis using an illuminator comprising a plurality of light sources generally conforming to a contoured surface and irradiating the contoured surface with substantially uniform intensity visible light. The light sources may comprise generally U-shaped fluorescent tubes that are driven by electronic ballasts. The spacing of the U-shaped tubes is varied to increase the output at the edges of the illuminator to make the output more uniform. Also, different portions of the tubes are cooled at different amounts, to improve uniformity. A light sensor monitors output from the U-shaped tubes to provide a signal for adjusting the output from the tubes. | 04-16-2015 |
20150105668 | Endoscopic, Exoscopic Or Microscopic Apparatus For Fluorescence Diagnosis - An endoscopic, exoscopic or microscopic apparatus for fluorescence diagnosis comprises a light source designed to emit light in a first spectral range and light in a second spectral range in a fluorescence mode The second spectral range is at least partly separate from the first spectral range. The light source has at least one first semiconductor illuminant which emits the light in the first spectral range in the fluorescence mode. The light source has at least one second semiconductor illuminant which emits the light in the second spectral range in the fluorescence mode. The apparatus comprises an open-loop or closed-loop control device, which keeps constant a preset ratio of a first intensity of the light in the first spectral range and a second intensity of the light in the second spectral range. | 04-16-2015 |
20150112204 | Systems and Methods for Selecting a Desired Quantity of Follicular Units - Systems and methods for selecting follicular units in a distribution of follicular units are provided. A selection parameter, such as a distance-related parameter separating the follicular units to be selected, may be used to determine a desired quantity of follicular units to be selected, such as a desired percentage of follicular units to be selected, and to help provide a substantially uniform distribution of selected follicular units. In addition, a characteristic parameter, such as a characteristic distance or characteristic density, may be determined. The characteristic parameter may be used in determining the desired quantity of follicular units to be selected and or may be used for treatment purposes. | 04-23-2015 |
20150112205 | Optical Speculum - A system for direct imaging and diagnosing of abnormal cells in a target tissue includes a disposable optical speculum and an image acquisition system having the speculum assembled on and mechanically secured thereto. The image acquisition system is arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets. An image analysis and control unit in communication with the image acquisition system analyzes the data sets and applies algorithms to the data sets for diagnosing abnormal cells. | 04-23-2015 |
20150119719 | APPARATUS AND METHOD FOR MEASUREMENT OF FLOW RATE OF CEREBROSPINAL FLUID IN A CONDUIT - Apparatuses and methods for measurement of flow rate of cerebrospinal fluid in a conduit are provided. The apparatus comprises a heating element mounted on the conduit, the heating element arranged for heating the CSF flowing through the conduit for generating bubbles. The apparatus further comprises two optical sensing devices mounted sequentially on the conduit and downstream from the heating element. The first optical sensing device and the second optical sensing device are separated by a predetermined device interval. Both the first and the second optical sensing devices comprise an optical emitter and an optical detector. The apparatus further comprises a processing device coupled to the optical sensing devices, wherein the signals from the optical sensing devices are transmitted to the processing device for detection of bubbles, resulting in the detection of the flow velocity. The bubble size can be optimized by applying ultrasonic waves or thermal energy. | 04-30-2015 |
20150119720 | SYSTEMS AND METHODS FOR DETECTING HELD BREATH EVENTS - Systems and methods are provided for detecting held breath events. A physiological signal, such as a photoplethysmograph (PPG) signal, is processed to extract respiration-related morphology metric signals. The morphology signals are analyzed to determine when a patient's breath is being held. | 04-30-2015 |
20150119721 | SYSTEM AND METHOD FOR ASSESSING WOUND - The wound assessing method and system of the present teachings provide a convenient, quantitative mechanism for diabetic foot ulcer assessment. | 04-30-2015 |
20150119722 | IMAGE PROCESSING APPARATUS, MICROSCOPE SYSTEM, ENDOSCOPE SYSTEM, AND IMAGE PROCESSING METHOD - An image processing apparatus includes: an image acquiring unit configured to acquire image information representing an image acquired by irradiating a gland duct with excitation light and observing fluorescence generated in the gland duct; a fluorescence intensity computation unit configured to compute a value corresponding to intensity of the fluorescence as fluorescence intensity based on the image information; and an image determination unit configured to determine whether or not an endocrine cell exists in the gland duct based on the fluorescence intensity computed by the fluorescence intensity computation unit, and to determine abnormality of the gland duct based on a determination result of the endocrine cell. | 04-30-2015 |
20150133793 | SUBJECT INFORMATION ACQUISITION APPARATUS - A subject information acquisition apparatus comprises a casing in which a transmissive member capable of transmitting acoustic waves and laser beams therethrough is provided; a light irradiating unit disposed inside the casing so as to irradiate a subject with laser beams with the transmissive member interposed; an acoustic wave probe disposed inside the casing so as to receive acoustic waves with the transmissive member interposed; and a scanning mechanism disposed inside the casing so as to move the light irradiating unit and the acoustic wave probe in relation to the casing, wherein the casing is configured to be movable on the subject. | 05-14-2015 |
20150141839 | EFFICIENT MODULATED IMAGING - An apparatus for turbid sample measurement comprising a plurality of light sources for illuminating a turbid sample target area with non-spatial structured light, a projection system for illuminating the turbid sample target area with spatial structured light, a sensor for collecting light from the turbid sample target area, and a processor to analyze the data captured by the sensor to yield scattering and absorption coefficients of the turbid sample. A method comprises illuminating the sample with spatial structured light, collecting light reflected from the sample at a number of wavelengths, illuminating the sample with non-spatial structured light, collecting light reflected from the sample at a number of wavelengths, and combining the measurements of the collected light to obtain the optical properties of the sample and/or the concentration of absorbing or fluorescent molecules. The wavelengths of the spatial and non-spatial light sources are preferably different. | 05-21-2015 |
20150141840 | BIOLOGICAL SENSOR - A biological sensor capable of improving the signal-to-noise ratio of a detection signal obtained by a light-receiving element and amplified by an amplifier is provided. | 05-21-2015 |
20150141841 | Wound Measurement on Smart Phones - A smart phone is used to accomplish measurement of a wound surface area, when at least one flat marker device, which is a predefined reference, is placed near the wound and photographed by a smart phone. | 05-21-2015 |
20150148684 | DEVICES AND METHODS FOR PROFILING MICROBIOTA OF SKIN - Devices and methods for profiling microbiota of skin are described which include a microbe profiling device including a device head and a hand-held housing, the device head including an epidermis-engaging component and an access window and configured to dislodge microbes from a skin surface, and the hand-held housing defining an opening aligned with the access window, the hand-held housing including a motor operably coupled to a motivatable component, a substrate disposed in relation to the motivatable component and including a microbe-capture region, a location-capture component to detect a location of one or more regions of the skin surface as the epidermis-engaging component contacts said one or more regions, at least one sensor component to detect one or more signals emitted or reflected from the microbe-capture region, and a computing component including circuitry to associate the location of said one or more regions of the skin surface and the detected one or more signals. | 05-28-2015 |
20150148685 | DEVICES AND METHODS FOR PROFILING MICROBIOTA OF SKIN - Devices and methods for profiling microbiota of skin are described which include a microbe profiling device including a device head and a hand-held housing, the device head including an epidermis-engaging component and an access window and configured to dislodge microbes from a skin surface, and the hand-held housing defining an opening aligned with the access window, the hand-held housing including a motor operably coupled to a motivatable component, a substrate disposed in relation to the motivatable component and including signal-generating complexes, a location-capture component to detect a location of one or more regions of the skin surface as the epidermis-engaging component contacts said one or more regions, at least one sensor component to detect one or more signals emitted from the signal-generating complexes, and a computing component including circuitry to associate the location of said one or more regions of the skin surface and the detected one or more signals. | 05-28-2015 |
20150148686 | DEVICES AND METHODS FOR SAMPLING AND PROFILING MICROBIOTA OF SKIN - Devices and methods for profiling microbiota of skin are described which include a hand-held microbe profiling device including a housing defining an opening, the housing including at least one rotatable component at least partially disposed in the opening defined by the housing, an elongated flexible strip disposed on an outer surface of the at least one rotatable component, the outer surface of the elongated flexible strip positioned to contact one or more regions of a skin surface of an individual through the opening defined by the housing, a location-capture component to detect a location of one or more regions of the skin surface as the elongated flexible strip contacts said one or more regions, at least one sensor component to detect one or more signals emitted or reflected from the elongated flexible strip, and a computing component to associate the location of said one or more regions of the skin surface and the detected one or more signals. | 05-28-2015 |
20150289764 | SUBJECT OBSERVATION SYSTEM AND METHOD, AND CAPSULE-TYPE ENDOSCOPE SYSTEM - A subject observation system includes a light source and an image obtaining unit. The light source emits observation light including a spectral component of a wavelength and applies the light to a subject. The image obtaining unit images reflected light from an irradiation region of the subject to which the light has been applied and obtains at least two observation images in different wavelength regions based on image signals corresponding to a blue region, a green region and a red region. The light includes components of light emission spectra in the regions. The light emission spectrum in the blue region is smaller in a wavelength region in which absorption intensity for a specific observation target in the subject is relatively low than in other regions. | 10-15-2015 |
20150289765 | APPARATUS FOR FINDING A FUNCTIONAL TISSUE AREA IN A TISSUE REGION - The invention is directed to an apparatus for finding a functional tissue area in a tissue region. The apparatus has a measurement illuminating device suitable for emitting measurement illumination to the tissue region and a camera which can capture light reflected by the tissue region. The camera has a green channel and/or a blue channel wherein there is a change in an optical property of the light reflected by the tissue region during the stimulation thereof which is undertaken at least intermittently. An evaluation unit captures the change in the optical property only by a signal of the green channel and/or of the blue channel of the camera. A display unit can display an output signal of the evaluation unit for the functional tissue area in the tissue region. | 10-15-2015 |
20150305623 | METHODS FOR LOCALIZING AND TREATING A PARATHYROID ADENOMA - Parathyroid adenomas may be identified using optical probes which distinguish the diseased tissue from adjacent healthy tissue. Spectroscopic properties of the tissue may be used to distinguish healthy from diseased tissue. Traditional surgery to remove the parathyroid adenoma may be avoided by using techniques to occlude the blood supply to the diseased tissue. Occlusion may be accomplished by applying energy to the blood vessel such as with radiofrequency energy, ultrasound energy or laser energy. Cryogenic probes may also be used to occlude the blood flow. Clips, sutures or other mechanical mechanisms may also be used to occlude the flow, thereby destroying the diseased tissue. | 10-29-2015 |
20150305657 | Analysis of Breathing Data - A method of analysing breathing data representing a shape of the trunk of a subject | 10-29-2015 |
20150305662 | REMOTE ASSESSMENT OF EMOTIONAL STATUS - A software product encoding steps for execution by a computer to provide an interactive computer-to-computer link for remote communication between a patient's computer and a therapist's computer, comprising instructions for establishing two-way audio/visual communication between said patient's computer and said therapist's computer, and an emotional recognition algorithm in said patient's computer for recognizing said patient's emotional state. | 10-29-2015 |
20150309295 | MINIATURIZED IMAGING DEVICES, SYSTEMS AND METHODS - The invention provides miniaturized devices, systems and methods for imaging of biological specimens. The devices and system provide accurate alignment and modular mounting of imaging components internally and in relation to the target subject. In some embodiments, the invention provides devices, systems and methods for in vivo fluorescent brain imaging in freely-behaving rodents. | 10-29-2015 |
20150313533 | FIBER OPTIC BASED DEVICES AND METHODS FOR MONITORING SOFT TISSUE - Fiber optic based systems and related components and methods for monitoring soft tissue volume (pressure) and temperature change. | 11-05-2015 |
20150313545 | SYSTEM AND METHOD FOR MAPPING THE LOCATIONS OF CAPTURED CONFOCAL IMAGES OF A LESION IN SKIN TISSUE - A system is provided having a guide member with features, such as grid and axes, which spatially correlate to tissue with a lesion adjacent the guide member, and a template device upon the tissue aligned with the features having a first aperture over the guide member, and a second aperture over the tissue with the lesion. A microscope captures one or more images of the tissue via the second aperture at one or more locations each spatially correlated with a location selected or being mapped along the guide member in the first aperture. Prior to imaging and template device placement, marks are recorded along the guide member when part of a tracing sheet is positioned in a folded state over the lesion to establish spatial correlation of the features of the guide member to the lesion when in an unfolded state and positioned for use with the template device and microscope. | 11-05-2015 |
20150327755 | LIGHT SOURCE DEVICE AND SUBJECT OBSERVATION APPARATUS AS WELL AS LIGHT SOURCE CONTROL METHOD - A light source device includes: excitation light sources configured to emit a plurality of excitation light including mutually different spectra; wavelength converting members configured to wavelength-convert the excitation light emitted from the excitation light sources into light having mutually different spectra and configured to be disposed in a common application region of the excitation light; and a light source control unit configured to switch a combination of the excitation light sources that are lighted among the excitation light sources based on the observation mode including a normal light observation mode and a special light observation mode to highlight a particular observation target input to an input unit, wherein light emitted from the wavelength converting members is used as illumination light, and the illumination light corresponding to the observation modes is emitted from a same emitting portion. | 11-19-2015 |
20150333712 | FOUR-STAGE CIRCUIT ARCHITECTURE FOR DETECTING PULSED SIGNALS - An electrical circuit includes a sensor configured to generate a current signal comprising a first portion comprising a contribution from a target source and/or a second portion comprising a contribution from sources other than the target source, a trans-impedance amplifier that amplifies the current signal and generate a low noise signal, and a high pass filter that converts the low noise signal into an AC signal having a positive amplitude, a negative amplitude, and a zero cross-over point between the positive and negative amplitudes. The circuit also includes a positive integrating amplifier that receives the positive amplitude of the AC signal and generates a positive integrated value over an integration period, and a negative integrating amplifier that receives the negative amplitude of the AC signal and generates a negative integrated value over the integration period. The circuit further includes at least one analog-to-digital converter that receives the integrated values. | 11-19-2015 |
20150335233 | Optical Medical Instrument - An optical medical instrument, in particular an endoscope or exoscope, has an elongate tubular shaft, a heat source generating lost heat, and a heat pipe which extends inside the shaft, in the longitudinal direction of the shaft, and has a distal heat pipe end and a proximal heat pipe end, wherein the heat pipe is thermally coupled to the heat source in order to collect heat from the latter and remove the heat from the heat source. Between the distal heat pipe end and the proximal heat pipe end, the heat pipe is coupled thermally conductively and two-dimensionally to the shaft over at least a partial length of the heat pipe and over at least a partial circumference of the heat pipe, in order to remove heat from the heat pipe, over at least a partial length and over at least a partial circumference of the shaft, to the environment. | 11-26-2015 |
20150335247 | OPTICAL IMAGING SYSTEM - Provided is an optical imaging system which visualizes a deep portion of a scattering body. The optical imaging system generates an image of an object to be inspected by removing a signal resulting from light reflected and scattered once by a surface of the object to be inspected from the signal obtained by means of an optical system analogous to Optical Coherence Tomography, thereby extracting a signal resulting from multiply scattered light. | 11-26-2015 |
20150335248 | METHODS RELATED TO REAL-TIME CANCER DIAGNOSTICS AT ENDOSCOPY UTILIZING FIBER-OPTIC RAMAN SPECTROSCOPY - A method of achieving instrument independent measurements for quantitative analysis of fiber-optic Raman spectroscope system, the system comprising a laser source, a spectroscope and a fiber optic probe to transmit light from the laser source to a target and return scattered light to the spectroscope, the method comprising transmitting light from the laser source to a standard target having a known spectrum, recording a calibration spectrum of the scattered light from the standard target, comparing the known spectrum and the calibration system and generating a probe and/or probe-system transfer function, and storing the transfer function. Further provided is a method of performing real-time diagnostic Raman spectroscopy optionally in combination with the other disclosed methods. | 11-26-2015 |
20150335249 | CONTACT-TYPE ENDOSCOPE SERS PROBE, AND RELATED METHODS - A contact-type endoscope surface enhanced Raman scattering (SERS) probe includes a gradient-index (GRIN) lens, a transparent substrate adhered to the GRIN lens, and a rough metallic layer adhered to an opposite side of the transparent substrate from the GRIN lens. The GRIN lens focuses light from a Raman spectrometer onto the rough metallic layer, and the rough metallic layer is positioned at the distal end of the contact-type endoscope SERS probe. | 11-26-2015 |
20150335271 | A SYSTEM AND METHOD FOR EVALUATING RANGE OF MOTION OF A SUBJECT - The present invention provides a system and method for evaluating Range of Motion of a subject. An aspect of the present invention proposes a system for evaluating Range of Motion of a subject, comprising markers attached to at least two joints of a body part of the subject respectively; an image capturing device for capturing images of the markers when the subject is doing an exercise with the body part attached with the at least two markers; and an evaluating device communicated with the image capturing device, wherein the evaluating device includes a determining unit configured to determine whether the exercise done by the subject is valid for the evaluation of Range of Motion of the body part of the subject, and a calculating unit configured to, if the exercise is valid, calculate the parameters related to Range of Motion of the body part of the subject according to the images related to the valid exercise. Thus, the work load of clinicians can be greatly reduced during the process of evaluating Range of Motion, and the accuracy of the evaluation of Range of Motion can be improved as well. | 11-26-2015 |
20150342457 | DEVICE AND METHOD FOR DETECTION AND QUANTIFICATION OF THE VARIATION OF EYE DAMAGE CAUSED BY THE BLUE AND VIOLET LIGHT OF THE VISIBLE SPECTRUM - Method, device ( | 12-03-2015 |
20150342467 | Physiological Monitoring Methods - A monitoring apparatus includes a housing that is configured to be attached to a body of a subject. The housing includes a sensor region that is configured to contact a selected area of the body of the subject when the housing is attached to the body of the subject. The sensor region is contoured to matingly engage the selected body area. The apparatus includes at least one physiological sensor that is associated with the sensor region and that detects and/or measures physiological information from the subject and/or at least one environmental sensor associated with the sensor region that is configured to detect and/or measure environmental information. The sensor region contour stabilizes the physiological and/or environmental sensor(s) relative to the selected body area such that subject motion does not impact detection and/or measurement efforts of the sensor(s). | 12-03-2015 |
20150342535 | METHOD AND ASSOCIATED CONTROLLER FOR LIFE SIGN MONITORING - A method for life sign monitoring and associated controller is provided. The method includes: obtaining a video signal, performing an activity modeling on the video signal to provide an activity signal, performing a vital sign extraction on the video signal to provide a vital sign, performing a filtering on the vital sign in view of the activity signal to suppress a correlation between the activity signal and the vital sign, and accordingly providing a filtered vital sign; and, according to the filtered vital sign and whether the activity signal exceeds an activity threshold range, providing a joint decision for categorizing result of life sign monitoring to one of a plurality of predetermined episodes. | 12-03-2015 |
20150351633 | CONFOCAL SCANNING MICROSCOPE HAVING OPTICAL AND SCANNING SYSTEMS WHICH PROVIDE A HANDHELD IMAGING HEAD - A confocal microscope having a scanning head in the form of a hand piece ( | 12-10-2015 |
20150351636 | Three Dimensional Imaging of Veins - An apparatus and method for creating a three dimensional imaging system is disclosed. There is a first source of laser light and a second source of laser light having a wavelength different from the wavelength of the laser light of the first source. The laser light from the first and second sources are combined, and the combined laser light is transmitted to a scanner. The scanner further transmits the combined light to a surface to be imaged. | 12-10-2015 |
20150351682 | WRINKLE DETECTION APPARATUS AND WRINKLE DETECTION METHOD - A wrinkle detection apparatus is an apparatus for detecting a wrinkle area of skin included in an image. The wrinkle detection apparatus includes a first threshold processing unit that detects a first edge area included in the image by performing first threshold processing for comparing a gradient value that indicates a degree of change in pixel values in the image with a first threshold, a second threshold processing unit that detects a second edge area included in the image by performing second threshold processing for comparing the gradient value with a second threshold, and an edge selection processing unit that determines a wrinkle area based on an overlapping area in which the first edge area and the second edge area are overlapped. | 12-10-2015 |
20150359429 | WIRELESS PATIENT MONITORING DEVICE - A device for obtaining physiological information of a medical patient and wirelessly transmitting the obtained physiological information to a wireless receiver. | 12-17-2015 |
20150359461 | MEASURING METHOD, PEDESTAL AND MEASURING SYSTEM FOR DETERMINING BIOMETRIC DATA OF HUMAN FEET - The invention relates to a measuring method for determining biometric data of human feet, comprising the following steps providing a reference object, which has at least one reference pattern, providing a freely moveable image recording device, automatically detecting the relative position and the alignment of the image recording device relative to the reference object using the at least one reference pattern, automatically recording of several images by the image recording device, wherein each individual image is only recorded, when the relative position and the alignment of the image recording device relative to the reference object corresponds to a triggering position predetermined for the respective image, determining biometric data of the at least one foot by means of the recorded images. | 12-17-2015 |
20150359464 | APPARATUS AND METHOD FOR MOTION TRACKING IN BRAIN IMAGING - Disclosed is apparatus and method for motion tracking of a subject in medical brain imaging. The method comprises providing a light projector and a first camera; projecting a first pattern sequence (S | 12-17-2015 |
20150366453 | OPTICAL MEASUREMENT APPARATUS - A measurement probe is configured to be detachably attached to an optical measurement apparatus. The measurement probe has at an end surface thereof exit ends of a plurality of optical fibers. The optical measurement apparatus includes: an imaging unit that receives rays of light transmitted from the exit ends of the plurality of optical fibers and performs photoelectric conversion in order to generate and output an electric signal; and a partition unit that optically isolates paths for the rays of light transmitted from the exit ends of the plurality of optical fibers, from one another in a space from the end surface to a light reception surface of the imaging unit. The partition unit comes into contact with the end surface at one end of the partition unit, and comes into contact with the light reception surface of the imaging unit at another end of the partition unit. | 12-24-2015 |
20150366455 | SYSTEM AND METHOD FOR DETERMINING VITAL SIGN INFORMATION OF A SUBJECT - The present invention relates to remote photoplethysmography and in particular to a system ( | 12-24-2015 |
20150366475 | Physiological Monitoring Devices Having Sensing Elements Decoupled from Body Motion - A monitoring device includes a sensor band configured to be secured around an appendage of a subject, and a sensing element movably secured to the sensor band via a biasing element. The sensor band has a first mass, and the sensing element has a second mass that is less than the first mass. The biasing element is configured to urge the sensing element into contact with a portion of the appendage, and the biasing element decouples motion of the band from the sensing element. A monitoring device includes a band that is configured to be secured around an appendage of a subject. One or more biasing elements extend outwardly from the band inner surface and are configured to contact the appendage. A sensing element is secured to the band inner surface. The one or more biasing elements decouples motion of the band from the sensing element. | 12-24-2015 |
20150374303 | SYSTEMS, METHODS, AND COMPUTER-READABLE MEDIA FOR TIME LAPSE IMAGE COMPARISON IN GENETIC DISORDER ANALYSIS - Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information. | 12-31-2015 |
20150374304 | SYSTEMS, METHODS, AND COMPUTER READABLE MEDIA FOR USING DESCRIPTORS TO IDENTIFY WHEN A SUBJECT IS LIKELY TO HAVE A DYSMORPHIC FEATURE - Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information. | 12-31-2015 |
20150374305 | SYSTEMS, METHODS, AND COMPUTER-READABLE MEDIA FOR DETERMINING WHEN A SUBJECT IS LIKELY TO BE AFFECTED BY A GENETIC DISORDER - Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information. | 12-31-2015 |
20150374306 | SYSTEMS, METHODS, AND COMPUTER-READABLE MEDIA FOR DETERMINING A LIKELY PRESENCE OF A GENETIC DISORDER - Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information. | 12-31-2015 |
20160000330 | Diagnostic Instrument and Method - A diagnostic instrument comprises a monochromatic light source, transmission means to transmit light from the light source to a test site, collection means to transmit scattered light from the test site, and spectral analysis apparatus to receive light from the collection means, the spectral analysis apparatus comprising a diffraction grating having a first grating element and a second grating element, wherein the first grating element diffracts light within a first wavelength range and the second grating element diffracts light within a second wavelength range, the spectral analysis apparatus further comprising a light-sensing apparatus, the first grating element arranged to diffract light onto a first area of the light-sensing apparatus and the second grating element arranged to diffract light onto a second area of the light-sensing apparatus. | 01-07-2016 |
20160000370 | 2D SCANNING VIDEOKYMOGRAPHY SYSTEM FOR ANALYZING VIBRATION OF VOCAL-FOLD MUCOSA, AND METHOD OF ANALYZING VIBRATION OF VOCAL-FOLD MUCOSA USING THE SAME - Disclosed is a 2D scanning videokymography system for analyzing a vibration of vocal-fold mucosa, including: a laryngoscope for observing vocal folds; a light source for illuminating the vocal folds; a video camera for recording and storing images observed through the laryngoscope; a computer incorporating an image capture unit for converting a video signal transmitted from the video camera into a digital image signal, a storage unit for storing the digital image signal, a control unit for analyzing the image signal of the storage unit and displaying the analysis results on a monitor, and analysis software for analyzing the image signal of the storage unit; and a monitor for displaying a captured image and analysis results. | 01-07-2016 |
20160000377 | APPARATUS OF NON-TOUCH OPTICAL DETECTION OF VITAL SIGNS ON SKIN FROM MULTIPLE FILTERS - A microprocessor is operably coupled to a camera from which patient vital signs of skin are determined. A temporal variation of images of skin from the camera is generated from multiple filters and then amplified from which the patient vital sign, such as heart rate or respiratory rate, can be determined and then displayed or stored. | 01-07-2016 |
20160007829 | IMAGE PROCESSING DEVICE AND METHOD FOR OPERATING ENDOSCOPE SYSTEM | 01-14-2016 |
20160007830 | IMAGE PROCESSING DEVICE AND METHOD FOR OPERATING ENDOSCOPE SYSTEM | 01-14-2016 |
20160007856 | FLUORESCENCE OBSERVATION APPARATUS | 01-14-2016 |
20160007904 | THE COLLECTION OF MEDICAL DATA | 01-14-2016 |
20160015298 | FOOT MEASURING DEVICE - An apparatus for measuring the dimensions of human feet is comprised of a base and a cover, which fits over it to define the borders of two essentially rectangular wells into which the feet to be measured are placed. A pressure pad assembly comprising a matrix of sensors is placed at the bottom of base. The walls of the wells are defined by PCBS comprising arrays comprised of a multitude of emitter/detector pairs, which are used to make length and width measurements of said feet. MCUs on the pressure pad assembly and computation means comprise software algorithms that automatically make length, width, and pressure measurements and correct errors in the length and width measurements caused by misalignment of the feet in the wells. Methods of using the apparatus are also presented. | 01-21-2016 |
20160029893 | MICROSCOPY IMAGING DEVICE WITH ADVANCED IMAGING PROPERTIES - Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm | 02-04-2016 |
20160029964 | Physiological Monitoring Devices with Adjustable Signal Analysis and Interrogation Power and Monitoring Methods Using Same - A monitoring device configured to be attached to a body of a subject includes a sensor configured to detect and/or measure physiological information from the subject, and a processor coupled to the sensor that is configured to receive and analyze signals produced by the sensor. The processor is configured to change signal analysis frequency and/or sensor interrogation power in response to detecting a change in subject activity, a change in subject stress level, a change in environmental conditions, a change in time, and/or a change in location of the subject. | 02-04-2016 |
20160038032 | Pre-Intubation Examination Apparatus and Probe - Pre-intubation examination apparatus and method for generating digital pre-intubation examination files for assisting successful intubations. The digital pre-intubation examination files include personal patient details, facial photographic data, one or more standard exterior patient anatomical measurements determined from the facial photographic data, and a clinician's subjective rating of a patient on one or more of the standard intubation classifications. The pre-intubation examination apparatus can be implemented either as a standalone pre-intubation examination probe or a pre-intubation examination accessory for use with a commercially available handheld digital device, for example, a computer tablet. | 02-11-2016 |
20160045114 | Method and System for Imaging and Collection of Data for Diagnostic Purposes - A system for acquiring data regarding a wound in tissue comprises at least one light source configured to directly illuminate a target surface with a homogeneous field of excitation light. An optical sensor is configured to detect signals responsive to illumination of an illuminated portion of a wound and the area around the wound. A thermal sensor is configured to detect thermal information regarding the illuminated portion of the wound and the area around the wound. A processor receives the detected signals and the detected thermal information and outputs data regarding the illuminated portion of the wound and the area around the wound. The output data may include wound size of the illuminated portion of the wound, bacterial load of the illuminated portion of the wound, or at least one temperature associated with the illuminated portion of the wound and the area around the wound. The data output by the processor may be displayed on a display of the system. | 02-18-2016 |
20160045115 | System for Reconstructing Surface Motion in an Optical Elastography System - A method for an optical elastography system converts digital images of an actuated breast into a description of surface motion. The surface motion can subsequently be used to ascertain whether the breast has regions of abnormal stiffness, e.g., indicating a significant likelihood of breast cancer. The steps of the method use a model based segmentation to identify profile of the breast in each image, and for each pair of images computing skin surface motion using an optical flow algorithm. This method eliminates a preliminary step of placing fiducial markers on the subject. | 02-18-2016 |
20160045163 | PATIENT INTERFACE FOR REUSABLE OPTICAL SENSOR - A disposable patient interface includes a reusable sensor that removably mounts within a shoe of the disposable patient interface when at least one protrusion on opposite ends of the sensor removably lock with corresponding at least one aperture on opposite portions of the shoe. The patient interface includes a compliant structure which conforms to a patient's body upon placement thereon without causing wrinkles in the compliant structure so as to maximize adhesion of the compliant structure against skin on the patient's body when the compliant structure is conformed to muscle underlying skin on the patient's body. | 02-18-2016 |
20160058310 | BIOLOGICAL INFORMATION DETECTION DEVICE - A biological information detection device includes: a light emitting unit which irradiates a subject with light; a first light receiving unit which receives light from the subject; a second light receiving unit which receives light from the subject; and a beam which is provided between the first light receiving unit and the second light receiving unit, in a plan view in a vertical direction of a light receiving surface of the first light receiving unit. | 03-03-2016 |
20160058362 | ACQUIRING CERVICAL IMAGES - The invention provides a system ( | 03-03-2016 |
20160061726 | Reflective Surface Treatments for Optical Sensors - An electronic device includes one or more light emitters for emitting light toward an object and one or more light detectors for collecting light exiting the object. A reflective coating, surface, or surface finish can be applied adjacent to the area to which light is emitted and/or through which light exits in order to increase the light collected by the light detector. The reflective coating can be oriented so as to reflect light back into the object. | 03-03-2016 |
20160061808 | MOLECULAR CELL IMAGING USING OPTICAL SPECTROSCOPY - The present invention provides a method and system for identification and isolation of cells from tissues using optical spectroscopy. The method includes accessing the cells using an access corridor, measuring the cells using optical spectroscopy, comparing the spectra of the cells to signature spectra, using the comparison to identify the cells and removing the cells into a container. The system includes an access corridor, a probe for measuring the cells, a resection tool, a collection tube and a collection container. | 03-03-2016 |
20160066781 | HEAD AND EYE TRACKING - Embodiments of the invention relate to a method of extracting eye velocity information from a video footage having a plurality of frames, comprising detecting at least part of an eye in at least two frames of the video footage, applying an optical flow algorithm to the at least two frames of the video footage to extract pixel velocity information, and determining a statistical measure from the pixel velocity information within the detected at least part of the eye. Other embodiments of the invention relate to a method of extracting head image trajectory information from a video footage having a plurality of frames, comprising detecting at least part of a facial region of the head image in at least two frames of the video footage, determining a measure of the movement of the at least part of a facial region between the at least two frames, and determining a transformation map from the measure of the movement. | 03-10-2016 |
20160066791 | Scanned Laser Vein Contrast Enhancer Using One Laser - The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like. | 03-10-2016 |
20160081602 | METHODS AND SYSTEMS FOR PROVIDING POWER TO LIGHT SOURCES OF A PHYSIOLOGICAL MONITOR - Systems and methods for providing power to a light source of a physiological system and for generating a desired signal. The physiological system may comprise a light drive circuit that may provide a digital signal to the light source of the physiological system. The digital signal may comprise a plurality of pulses. The plurality of pulses may include one or more features that may be adjustable to vary the power provided to the light source. For example, the pulses may have a varying width. The light drive circuit may be configured to provide power to the light source during each pulse of the plurality of pulses. The system may further comprise a front end circuit configured to receive the light generated by the light source in response to the plurality of pulses, where the light is attenuated by a body tissue of a patient. The front end circuit may comprise a response time. The at least one period of the plurality of pulses may be substantially shorter than the response time of the front end channel circuit. | 03-24-2016 |
20160089013 | METHOD AND SYSTEM FOR FLUORESCENT IMAGING WITH BACKGROUND SURGICAL IMAGE COMPOSED OF SELECTIVE ILLUMINATION SPECTRA - A surgical site is simultaneously illuminated by less than all the visible color components that make up visible white light, and a fluorescence excitation illumination component by an illuminator in a minimally invasive surgical system. An image capture system acquires an image for each of the visible color components illuminating the surgical site and a fluorescence image, which is excited by the fluorescence excitation component from the illuminator. The minimally invasive surgical system uses the acquired images to generate a background black and white image of the surgical site. The acquired fluorescence image is superimposed on the background black and white image, and is highlighted in a selected color, e.g., green. The background black and white image with the superimposed highlighted fluorescence image is displayed for a user of the system. The highlighted fluorescence image identifies tissue of clinical interest. | 03-31-2016 |
20160089073 | AUTOMATIC VISUAL REMOTE ASSESSMENT OF MOVEMENT SYMPTOMS IN PEOPLE WITH PARKINSON'S DISEASE FOR MDS-UPDRS FINGER TAPPING TASK - A system and method for assessing patient movement for Parkinson's disease includes capturing a video of a subject performing a finger tapping sequence comprising a predetermined number of open and close periods. According to an exemplary embodiment, a system and method includes extracting a region of interest for each frame of the video and generating a projection of the region of interest for each frame of the video using perpendicular vector projections in a direction or plurality of directions. | 03-31-2016 |
20160106340 | SYSTEM AND METHOD FOR DETERMINING RESPIRATION RATE FROM A VIDEO - What is disclosed is a system and method for determining respiration rate from a video of a subject. In one embodiment, a video is received comprising plurality of time-sequential image frames of a region of a subject's body. Features of pixels are extracted from that region from each image frame and vectors formed from these features. Each image frame has an associated feature vector. A N×M video matrix of the vectors of length N is constructed such that a total number of columns M in the video matrix correspond to a time duration over which the subject's respiration rate is to be determined. The video matrix is processed to obtain a matrix of eigenvectors where principal axes of variations due to motion associated with respiration are contained in a first few eigenvectors. One eigenvector is selected from the first few eigenvectors. A respiration rate is obtained from the selected eigenvector. | 04-21-2016 |
20160113503 | RAPID RATE-ESTIMATION FOR CELL PHONES, SMART WATCHES, OCCUPANCY, AND WEARABLES - Techniques for respiratory and metabolic monitoring in mobile devices, wearable computing, security, illumination, photography, and other applications may use a phosphor-coated broadband white LED to produce broadband light, which may be transmitted along with ambient light to a target (e.g., ear, face, wrist, or the like). Some scattered light returning from a target may be passed through a spectral filter to produce multiple detector regions sensitive to a different waveband and/or wavelength range, and the detected light may be analyzed to determine a measure of a respiratory rate or effort. In the absence of LED light, ambient light may be sufficient illumination for analysis. The disclosed techniques may provide identifying features of type or status of a tissue target (e.g., respiratory rate, heart rate, heart rate variability, heart function, lung function, fat content, hydration status, confirmation of living tissue, and the like). | 04-28-2016 |
20160120408 | NON-CYLINDRICAL HYPOTUBES - A non-cylindrical hypotube is disclosed, such as for use in OCT and endoscopy. The hypotube is defined by a non-cylindrical, rotationally symmetric tube and has an interior, a proximal-end section with an outer diameter D | 05-05-2016 |
20160120421 | OPTICAL DETECTION UNIT AND BIOLOGICAL INFORMATION DETECTION DEVICE - An optical detection unit includes a light emitting portion | 05-05-2016 |
20160120444 | OPTICAL SENSING APPARATUS AND MEASURING METHOD THEREOF - An optical sensing apparatus including a light sensor, a plurality of light-emitting devices, and a controller is provided. The light sensor is disposed on a substrate. The light sensor senses a light reflection signal in a sensing area of the optical sensing apparatus. The light-emitting devices are disposed on the substrate and around the light sensor. The light-emitting devices provide an optical signal to be transmitted into the human tissue. Then, the optical signal is reflected by the human tissue to generate the light reflection signal. The controller determines whether the position of the human tissue has been changed in the sensing area. The controller drives at least one light-emitting device of the light-emitting devices and adjusts the light intensity thereof to provide the appropriate optical signal. Besides, a measuring method of the optical sensing apparatus is proposed. | 05-05-2016 |
20160120459 | Wound Acknowledgement Interface - Systems, tools, and methods for providing wound data and/or information to a remote location for clinical assessment and acknowledgement are disclosed. | 05-05-2016 |
20160120604 | MEASUREMENT DEVICE FOR SKIN PROPERTIES AND NON-INVASIVE TREATMENT DEVICE - The application provides a non-invasive measurement device ( | 05-05-2016 |
20160143538 | CAMERA BASED PHOTOPLETHYSMOGRAM ESTIMATION - A system for estimating a photoplethysmogram waveform of a target includes an image processor configured to obtain images of the target and a waveform analyzer. The waveform analyzer is configured to determine a weight of a portion of the target. The weight is based on a time variation of a light reflectivity of the portion of the target. The time variation of the light reflectivity of the target is based on the images. The waveform analyzer is further configured to estimate a PPG waveform of the target based on the weight of the portion and the time variation of the light reflectivity of the portion. | 05-26-2016 |
20160143589 | BIOLOGICAL MEASUREMENT DEVICE AND BIOLOGICAL MEASUREMENT METHOD - A biological measurement device includes a phase modulation type interferometer, a first stage, a light transmitting plate, and a second stage. The first stage is able to retain a target which is a biological body. The light transmitting plate is disposed between the first stage and the interferometer in a direction of an optical axis of measurement light of the interferometer. The second stage supports the light transmitting plate. The first stage is configured to expand by a pressure of a gaseous body in the direction of the optical axis of the measurement light of the interferometer and to press the target against the light transmitting plate. | 05-26-2016 |
20160150949 | Air Removal and Fluid Transfer From a Closed System | 06-02-2016 |
20160150960 | OPTICAL DETECTING MODULE WITH WATERPROOFING FUNCTION | 06-02-2016 |
20160150963 | ONE-PHOTON INTEGRATED NEUROPHOTONIC SYSTEMS | 06-02-2016 |
20160150966 | AUTOMATIC CONTINUOUS PATIENT MOVEMENT MONITORING | 06-02-2016 |
20160150987 | BIOSIGNAL PROCESSING APPARATUS AND METHOD | 06-02-2016 |
20160151007 | BIOLOGICAL INFORMATION MEASURING DEVICE AND BIOLOGICAL INFORMATION MEASURING METHOD | 06-02-2016 |
20160151008 | BIOLOGICAL INFORMATION MEASURING DEVICE | 06-02-2016 |
20160157700 | UNIVERSAL HANDLE - The claimed subject matter provides systems and/or methods that facilitate employing a universal handle that provides various functionality and communicates with various network(s), device(s), and the like. The universal handle can be a handheld device that is auto-configured to implement rich functionality. Further, the universal handle can support remote diagnostic, prognostic, and control capabilities. Moreover, the universal handle can mate with disparate device(s), network(s), instrument(s), node(s), universal handle(s), and so forth to communicate data there between. Applications of the universal handle can be medically related, industry related, military related, etc. The universal handle can collect data directly and/or by controlling managed external device(s); the collected data can thereafter be analyzed, aggregated, stored, transmitted, outputted, and so forth by the universal handle. | 06-09-2016 |
20160157722 | FLUORESCENCE OBSERVATION APPARATUS - A fluorescence observation apparatus including a light source that radiates illumination light and excitation light; a return-light-image generating portion and a fluorescence-image generating portion that generate a return-light image and a fluorescence image, respectively; a fluorescence detecting portion that detects a fluorescence region in the fluorescence image; a return-light-image adjusting portion that adjusts gradation values of the return-light image; a superimposed-image generating portion that generates a superimposed image by using the return-light image, in which the gradation values have been adjusted, and the fluorescence image; and a coefficient setting portion that sets, in the case in which the fluorescence region is detected, a degree-of-reduction of the gradation values, so that the gradation values of the return-light image are decreased as compared with the case in which the fluorescence region is not detected. | 06-09-2016 |
20160157726 | PROJECTION IMAGE GENERATING DEVICE, METHOD AND PROGRAM - A view point is set inside a hollow organ, a clip plane crossing an internal cavity of the hollow organ is set in a position spaced apart in a visual line direction from the view point, a field of view from the view point is divided into a first field-of-view range in which the inside of the hollow organ is viewed and a second field-of-view range other than the first field-of-view range, a projection image is acquired using a template which is defined so that an inner wall surface of a large intestine is able to be drawn in the first field-of-view range, a projection image is acquired using a template which is defined so that a contact surface with the inner wall surface of the air region of the large intestine is able to be drawn in the second field-of-view range, and the projection images are connected. | 06-09-2016 |
20160157770 | METHOD AND DEVICE FOR COLLECTING DATA FOR POSTUROGRAPHY - A method and a device for collecting data for posturography comprising a magnetizable body and an acceleration sensor are located on the platform, which magnetizable body and acceleration sensor are connected to a computer by means of an A/D converter. An electromagnet is located under the platform and is attached so as to be displaceable in two axes parallel to the plane of the platform, wherein the electromagnet is connected to an A/D converter and a power supply by means of a circuit, and a time-variable display, which is connected to the A/D converter, and a digital camera which are connected to the computer. By means of the method and the device it is now possible to standardize posturographic measurements, simultaneously detect the acceleration and the position of the platform, and more variably carry out provocations. | 06-09-2016 |
20160157947 | Robotic Devices and Systems for Performing Single Incision Procedures and Natural Orifice Translumenal Endoscopic Surgical Procedures, and Methods of Configuring Robotic Devices and Systems - Example embodiments relate to surgical devices, systems, and methods. The system may include a port assembly and instrument arm assembly. The port assembly may have first and second end sections. The first end section may include a first end channel and first gate assembly. The second end section may include a second end channel, second gate assembly, and anchor port. The first and second gate assemblies may be configurable to transition between an open position to allow access through the first and second end channels, respectively, and a closed position to prevent access to same. The instrument arm assembly may include a shoulder section securable to the anchor port, first arm section secured to the shoulder section, elbow section secured to the first arm section, second arm section secured to the elbow section, wrist section secured to the second arm section, and end effector section secured to the wrist section. | 06-09-2016 |
20160166161 | Novel Design Considerations in the Development of a Photoplethysmography Ring | 06-16-2016 |
20160166205 | MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY | 06-16-2016 |
20160166333 | OPTICAL TARGETING AND VISUALIZATION OF TRAJECTORIES | 06-16-2016 |
20160174841 | SYSTEM FOR REMOTE CHILD MONITORING | 06-23-2016 |
20160174845 | APPARATUS FOR THE NON-INVASIVE MEASUREMENT OF TISSUE FUNCTION AND METABOLISM BY DETERMINATION OF STEADY-STATE FLUORESCENCE ANISOTROPY | 06-23-2016 |
20160174846 | METHOD AND SYSTEM FOR MEASURING ANATOMICAL DIMENSIONS FROM A DIGITAL PHOTOGRAPH ON A MOBILE DEVICE | 06-23-2016 |
20160174847 | IMAGE ACQUISITION APPARATUS, BIOLOGICAL BODY INFORMATION ACQUISITION APPARATUS, AND ELECTRONIC APPARATUS | 06-23-2016 |
20160174878 | System and Method for Measuring Skin Firmness | 06-23-2016 |
20160174897 | Sensor Embedded Wearable Technology Glove | 06-23-2016 |
20160175652 | METHOD AND APPARATUS FOR EXERCISE MONITORING COMBINING EXERCISE MONITORING AND VISUAL DATA WITH WIRELESS WEARABLE DEVICES | 06-23-2016 |
20160183802 | FLUORESCENT IMAGE ACQUISITION AND PROJECTION APPARATUS FOR REAL-TIME VISUALIZATION OF INVISIBLE FLUORESCENT SIGNAL - A fluorescent image acquisition and projection method includes the steps of generating, by a plurality of light sources, invisible fluorescence under control of a control device and obtaining, by a detection unit, a signal of an invisible fluorescent image from a target object. The method further includes the steps of receiving from the detection unit and processing the invisible fluorescent image signal of the target object into a visible fluorescent signal, transmitting the visible fluorescent signal to a projector unit, and projecting, by the projector unit, the visible fluorescent signal onto the target object. | 06-30-2016 |
20160183865 | METHOD FOR DIAGNOSING CRANIAL BONE DISPLACEMENT - A method for diagnosing cranial one displacement by determining the location of characteristic points on the skull such as an occipital point situated on the protuberance of the occipital bone at the centre of the occiput, a frontal point situated at the intersection of the external base of the skull and the sagittal suture of the frontal bone, a right-hand temporal point situated at the intersection of the external base of the skull and a vertical line from the right-hand mandibular notch, a left-hand temporal point situated at the intersection of the external base of the skull and a vertical line from the left-hand mandibular notch, and a diagnostic point situated at the intersection of a line passing through the occipital and frontal points and a line passing through the right-hand temporal point and the left-hand temporal point; the distance between the occipital and frontal points is measured along the right-hand outer part of the head and, separately, along the left-hand outer part of the head, the distance between the right-hand and left-hand temporal points is measured across the frontal bone, and the distance between said points is measured across the occipital bone, the distances between the occipital point and the diagnostic point and between the frontal point and the diagnostic point are measured across the upper part of the skull, and the distances between the left-hand temporal point and the diagnostic point and between the right-hand temporal point and the diagnostic point are measured, the values of the corresponding results obtained are compared and cranial bone displacement is determined according to the deviation of said values from zero. | 06-30-2016 |
20160192841 | BIOLOGICAL INFORMATION MEASURING MODULE AND BIOLOGICAL INFORMATION MEASURING APPARATUS | 07-07-2016 |
20160192842 | BIOLOGICAL INFORMATION MEASURING MODULE AND BIOLOGICAL INFORMATION MEASURING APPARATUS | 07-07-2016 |
20160192847 | BIOLOGICAL INFORMATION MEASURING MODULE AND BIOLOGICAL INFORMATION MEASURING APPARATUS | 07-07-2016 |
20160192885 | APPARATUS AND METHOD FOR MEASURING BIOLOGICAL SIGNAL | 07-07-2016 |
20160198961 | Applications of hyperspectral laser speckle imaging | 07-14-2016 |
20160198982 | ENDOSCOPE MEASUREMENT TECHNIQUES | 07-14-2016 |
20160249978 | PERICARDIAL ACCESS CATHETERS AND METHODS FOR USE | 09-01-2016 |
20160374621 | Wearable Monitoring Device - A wearable device includes a housing, at least one optical emitter supported by the housing, wherein the at least one optical emitter is configured to generate modulated light, at least one optical detector supported by the housing, and a tip removably secured to the housing. The tip includes first and second portions, wherein the first portion directs light along a first path from the at least one optical emitter to a body of a subject wearing the device, and wherein the second portion directs light from the body of the subject to the optical detector along a second path that is different from the first path. The device may also include an analog-to-digital converter, a motion sensor, and a processor. The processor executes a first filter that attenuates sunlight noise and a second filter that attenuates motion artifacts. | 12-29-2016 |
20160377413 | Methods and devices for detection of movements and deformations of bodies or parts thereof - A device for detecting body deformations or movements of a solid body (e.g. human body) includes a light source, a light receiver receiving a light signal and detecting its variations, an elastic lightguide, including optical imperfections, optically connected to the light source and light receiver, and attached to the body. The body's deformations effect the lightguide's deformations, producing the variations. The lightguide can be made as a single-piece or multiple-piece, wherein gaps between the pieces function as optical imperfections. The light variations are converted into electrical signals for further processing by a control system that can be respectively programmed. Particularly, the device can be implemented for monitoring/training human spine movements for treatment. Other implementations are measuring a position, displacement, speed and acceleration of the body or its parts relative to each other. The device can also measure stretching, shifting, shearing, twisting and other deformations of the body. | 12-29-2016 |
20170231480 | OBSERVATION SYSTEM | 08-17-2017 |
20170231502 | OBSERVATION DEVICE | 08-17-2017 |
20170231530 | INTRAFRACTIONAL MOTION REDUCTION SYSTEM USING AUDIOVISUAL-AIDED INTERACTIVE GUIDANCE AND RELATED METHODS THEREOF | 08-17-2017 |
20170231531 | PATIENT MONITORING SYSTEM AND METHOD | 08-17-2017 |
20170231569 | FOOTWEAR FOR MONITORING HEALTH CONDITION OF FOOT OF A USER AND A METHOD THEREOF | 08-17-2017 |
20170231706 | ILLUMINATED SURGICAL BARRIER | 08-17-2017 |
20170235118 | ILLUMINATION FILTER SYSTEM AND OBSERVATION SYSTEM FOR A MULTISPECTRAL FLUORESCENCE MICROSCOPE, MULTISPECTRAL FLUORESCENCE MICROSCOPE, AND MICROSCOPYING METHOD | 08-17-2017 |
20180020954 | METHOD AND SYSTEM FOR AUTOMATED BIOMECHANICAL ANALYSIS OF BODILY STRENGTH AND FLEXIBILITY | 01-25-2018 |
20180020985 | OPTICAL IMAGING SYSTEM AND METHOD OF MAKING AND USING THE SAME | 01-25-2018 |
20180024031 | Control of Industrial Water Treatment Via Digital Imaging | 01-25-2018 |
20190142327 | METHOD AND APPARATUS FOR MEASURING SACCADIC LATENCY | 05-16-2019 |
20220133233 | OPTICAL SHUNT REDUCTION USING OPTICALLY ABSORPTIVE MATERIALS IN A MEDICAL SENSOR - A patient monitoring sensor having a communication interface, through which the patient monitoring sensor can communicate with a monitor is provided. The patient monitoring sensor includes a light-emitting diode (LED) communicatively coupled to the communication interface and a detector, communicatively coupled to the communication interface, capable of detecting light. The patient monitoring sensor includes an optically absorptive material at least partially between the LED and the detector to reduce or prevent shunting of light to the detector. | 05-05-2022 |