Entries |
Document | Title | Date |
20080200779 | Implant Sensor and Control - An implant includes a humidity sensor for generating a signal indicative of humidity within the implant. A controller within the implant receives the signal indicative of humidity, and controls the implant based on the signal indicative of humidity. | 08-21-2008 |
20080214909 | Catheter With Microchannels For Monitoring The Concentration Of An Analyte In A Bodily Fluid - Catheter for monitoring the concentration of an analyte in a body fluid having an implantable distal area ( | 09-04-2008 |
20080221407 | Method for evaluating skin hydration and fluid compartmentalization - There is provided a system and method for evaluating skin hydration and fluid compartmentalization. The system includes a microneedle array configured to extract fluid from an interstitial space and a pressure sensor configured to measure a pressure differential between the interstitial space and ambient pressure during extraction of the fluid. A processor coupled to the pressure sensor is configured to compute a hydration index based on the pressure differential. A display coupled to the processor is configured to display the hydration index. | 09-11-2008 |
20080228048 | Physiological Sensors with Telemonitor and Notification Systems - Systems and methods are provided which enable communications to be initiated locally relative to an individual's developing physiological condition and remotely as the condition requires. Physiological sensors and associated medical delivery systems can be coupled to a unit wearable by an individual which can provide various audible or visual outputs and one or more manual inputs indicative of the individual's condition. A global positioning unit can be incorporated so that condition information as well as location information can automatically be provided, wirelessly, to a remote monitoring system for follow up as needed. | 09-18-2008 |
20080234559 | Analyte Meter Protectors and Methods - Analyte meter protectors, meters that include the same, and methods. | 09-25-2008 |
20080255434 | METHOD AND APPARATUS FOR PROVIDING DATA PROCESSING AND CONTROL IN MEDICAL COMMUNICATION SYSTEM - Methods and apparatus for providing data processing and control for use in a medical communication system are provided. | 10-16-2008 |
20080269574 | Diagnosing Peripheral Vascular Disease by Monitoring Oxygen Saturation Changes During a Hyperemia Phase - Peripheral vascular disease is diagnosed through measurements of oxygen saturation. In a specific implementation, peripheral vascular disease is diagnosed based on changes in oxygen saturation in tissue. Ischemia is induced, and then measurements of changes in oxygen saturation in tissue are made. Based on changes in oxygen saturation during a hyperemia phase, a diagnosis is provided of whether a patient has or does not have peripheral vascular disease. | 10-30-2008 |
20080287755 | METHOD AND APPARATUS FOR TREND ALERT CALCULATION AND DISPLAY - Embodiments of the present invention provide methods, apparatuses, and systems associated with detecting, monitoring, analyzing, and/or displaying analyte level trends in a body. In an embodiment, there is provided a method comprising obtaining a plurality of analyte measurements from a body using an analyte sensing device, and selecting two or more measurements of the plurality of measurements to calculate and display on a device associated with the analyte sensing device a rate of change of the analyte over a period of time spanning the two or more measurements. | 11-20-2008 |
20080294023 | Device, System, and Method for In-Vivo Analysis - A device, system and method for in-vivo analysis. An autonomous in-vivo device may include a magnet to detain at least a portion of a sample collected from a body lumen; a sensor to sense a property of the detained sample portion; and a transmitter to transmit data of the sensed property. | 11-27-2008 |
20080294024 | Glucose meter system and monitor - A handheld portable glucose meter includes a glucose sensor having a sensor output related to glucose in a blood sample. A display is configured to display information to a user. A manual input is configured to receive user input data from the user. Communication circuitry is configured to send and/or receive data to and/or from a remote location. A controller controls operation of the handheld portable glucose meter. | 11-27-2008 |
20080294025 | Anti-Inflammatory Signal Molecules and Exercise - The present invention provides methods for assessing the effect of exercise on an individual by measuring changes in the concentration of a compound in the individual's blood. Specifically, the invention measures changes in the concentration of an anti-inflammatory signal molecule or endogenous morphine. Anti-inflammatory signal molecules include, for example, adrenocorticotropin (ACTH), cortisol, and interleukin-10 (IL-10). | 11-27-2008 |
20080319284 | METHOD FOR TRAINING A USER IN RECOGNITION OF THE USER'S BODILY FLUID ANALYTE CONCENTRATION AND CONCENTRATION TRENDS VIA USER-PERCEIVED SENSATIONS - A method for training a user in recognition of the user's bodily fluid analyte concentration and concentration trends includes monitoring a user's bodily fluid analyte concentration (for example, a user's whole blood glucose concentration) with an analyte monitoring module of a device for training a user in recognition of the user's bodily fluid analyte concentration. The method also includes generating, at a predetermined time interval, using a generation module of the device, a user-perceived sensation (e.g., a user-perceived vibratory sensation) that is proportional the user's bodily fluid analyte concentration in a predetermined manner. | 12-25-2008 |
20080319285 | Apparatus and Method for Measuring Constituent Concentrations within a Biological Tissue Structure - Apparatus for minimally invasively measuring concentrations of constituents contained within a biological tissue structure includes a microwave energy source arranged generate a range of microwave frequencies, a first antenna coupled to the microwave energy source and arranged to transmit at least a portion of the microwave energy into the tissue structure, a second antenna arranged to receive at least a portion of the microwave energy transmitted through the tissue structure, a signal processor arranged to determine the resonant frequency of the received microwave energy, and a data processor arranged to provide an output of the concentration of constituents within the biological tissue structure according to the determined resonant frequency. | 12-25-2008 |
20090012376 | Continuous Analyte Monitor and Method of Using Same - The use of an analyte-monitoring device for continuously monitoring analytes within a bodily fluid bypass flow path. A method of monitoring analytes in a patient by continuously monitoring analytes present in a bodily fluid of that patient within the bodily fluid bypass flow path is provided. | 01-08-2009 |
20090012377 | METHOD AND STRUCTURE FOR SECURING A MONITORING DEVICE ELEMENT - Structures and methods for attaching a device to a user's skin are provided. Embodiments include refreshing an adhesive attaching an element of an analyte monitoring device so that a first adhesive attaches the element of the analyte monitoring device during a first time period and a second adhesive attaches the element of the analyte monitoring device to the user's skin during a second time period. A sensor remains at least partially inserted into the user's while the refreshing of the adhesive from the first to the second adhesive occurs. | 01-08-2009 |
20090018411 | Analyte Test Device - An analyte test device is constructed as an integrated, single-use, disposable cartridge which can be releasably installed into a compatible analyte test monitor. In use, the device can be used in conjunction with the monitor to lance the skin of a patient to create a blood sample and, in turn, calculate the concentration of a particular analyte in the expressed blood sample. In one embodiment, the device includes a base and a cover which are affixed together to create a test cartridge which has a substantially flat and low profile design. A lancet carrier is disposed between the base and the cover and includes a anchor fixedly mounted on the base and a lancet support member which is slidably mounted on the base, the anchor and the lancet support member being connected by a spring. A lancet is removably mounted on the lancet support member is disposed directly beneath an analyte test strip which secured to the underside of the cover. In another embodiment, the device includes a cylindrical housing with an open top end and an open bottom end. A spring biased lancet is slidably mounted within the cylindrical housing. An analyte test strip is fixedly mounted within the cylindrical housing and is disposed at an acute angle relative to the lancet. | 01-15-2009 |
20090018412 | Medical unit with an apparatus for an examination of a patient and an associated method - The invention relates to a medical unit with an apparatus designed for the examination or treatment of a patient. The medical unit comprises at least one means designed for the collection or analysis of at least one substance exuded from the body of the patient during the course of a bodily process concomitantly to the examination or treatment of the patient with the apparatus. | 01-15-2009 |
20090018413 | IMPLANTABLE MEDICAL DEVICE FOR DIAGNOSTIC SENSING - An implantable medical device is provided for use with an external detector to detect an analyte in vivo. In one embodiment, the device consisting essentially of a substrate; a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening; a reacting component contained in each reservoir; and at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an analyte to be detected, wherein the reacting component remains inside the reservoirs and can react with the analyte to be detected, and wherein the device is adapted for implantation into the body of a patient. | 01-15-2009 |
20090024009 | Body fluid sampling device with a capacitive sensor - A body fluid sensing device with a body fluid capture structure and a body fluid measurement sensor positioned in the body fluid capture structure. A capacitance sensor is coupled to the body fluid measurement sensor. The capacitance sensor is used to assist in the positioning of a body part relative to the body fluid capture structure. | 01-22-2009 |
20090024010 | Hand-held analysis device having different setting modes - A handheld analysis device for examining a sample of body fluid, such as blood to analyze blood glucose, has a setting mode for changing various device settings to improve the changing of device settings. The handheld analysis device comprises a measurement unit, a microprocessor, a segment display, and an operating element. When the operating element is actuated, the device is placed in a selection mode and further actuation of the operating element, then in one of several setting modes, the user can efficiently change device settings by inputting data and/or control commands. | 01-22-2009 |
20090036758 | SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk. | 02-05-2009 |
20090043177 | METHOD FOR INTEGRATING FACILITATED BLOOD FLOW AND BLOOD ANALYTE MONITORING - A method for the integrated facilitization of blood flow and monitoring of blood analyte concentration (for example, blood glucose concentration) includes implanting a stent configured to facilitate blood flow into a cardiovascular system of a user's body with the stent having attached thereto a continuous blood analyte determination module of a blood analyte monitoring system. The method also includes disposing a reader module of the blood analyte monitoring system external to the user's body and in proximity to a portion of the user's skin layer and monitoring blood analyte concentration via (i) emitting an RF carrier signal from the reader module toward the stent; (ii) receiving the RF carrier signal at a reflection antenna of the continuous blood analyte determination module; (iii) reflecting a modulated signal by the reflection antenna with the modulated signal being encoded with a blood analyte concentration determined by a sensor of the continuous blood analyte determination module; (iv) receiving the modulated signal by the reader module; and (v) decoding the analyte concentration from the modulated signal by the reader module. | 02-12-2009 |
20090048499 | Sensor film for transcutaneous insertion and a method for making the sensor film - There is provided a thin film ( | 02-19-2009 |
20090062630 | Sensor permitting detection of a substance in the body of a living being - A sensor is disclosed for permitting detection of a substance in the body of a living being. In at least one embodiment, the sensor includes probe molecules, for binding the substance that is to be detected, and marking elements designed in such a way that the binding of the probe molecules to the substance to be detected is detectable by way of an imaging modality. For example, antigens or pathogens that are present only in a low concentration can be detected. | 03-05-2009 |
20090069649 | Method and System for Providing Analyte Monitoring - Methods and apparatuses for determining an analyte value are disclosed. | 03-12-2009 |
20090069650 | Integrated Analyte Sensor And Infusion Device And Methods Therefor - Method and system for providing an integrated analyte monitoring system and on-body patch pump with multiple cannulas and a sensor combination is provided. | 03-12-2009 |
20090082646 | ACCESS DISCONNECT DETECTION SYSTEM - An access site disconnection system and method are disclosed. Radio frequency transmitters and receivers are placed near an access site. When a patient receives dialysis treatment, wetness may arise from blood if the access needle becomes disconnected from the access site. Radio-frequency transmitters are mounted on or near gauze or other absorbent material placed adjacent the access site, as are radio-frequency receivers. After the sensors are placed, the dialysis machine and radio-frequency control circuit may be initialized or baselined, and dialysis treatment, such as hemodialysis, begun. If blood leaks from the access site, such as if the access needle is dislodged, the blood attenuates the radio frequency transmissions, which are detected by the receivers. A signal is sent to a controller or to an output device to raise an alert or sound an alarm. | 03-26-2009 |
20090082647 | DETECTING ACCESS DISCONNECT USING NEEDLE SLEEVE - An access needle for extracorporeal therapy is equipped with a mount and a sleeve having a metal or magnetic component at its distal end. The mount includes a sensor for detecting when the distal end is pressed against the mount. The sensor is a hall-effect sensor or a proximity sensor. When therapy is begun, the sleeve is rolled up and urged against the mount, exposing the needle for use with the patient. While the sleeve, and the piece of metal or magnet, remains in contact with the sensor, the needle has not been dislodged and therapy may continue. If the needle is dislodged, the sleeve pushes away from mount, moving the metal or magnet away from the sensor. The sensor notes the dislodgement and sends a signal to alert the patient or a caregiver. | 03-26-2009 |
20090082648 | METHOD AND APPARATUS FOR TREATING SKIN PRIOR TO BIOSENSOR INSERTION - Embodiments of the present invention provide a device and method for treating animal skin to produce tautness in the skin during the insertion of an analyte sensor. A device in accordance with embodiments of the present invention includes a housing that partially encloses a cavity and is adapted for mounting onto animal skin and a sensor insertion module adapted to insert an analyte sensor through animal skin. | 03-26-2009 |
20090088612 | ACCESS DISCONNECT DETECTION - Techniques are disclosed for monitoring the flow of blood returning to a patient from an extracorporeal therapy machine, such as a hemodialysis machine or an apheresis machine. Blood returning from such a machine is pumped, typically by a peristaltic pump, which returns the blood in pulsed flow or pulses. This flow can be sensed by Doppler flow sensors or accelerometers as it returns to the patient. If the flow is interrupted by dislodgement of the venous access needle, or by leaking of blood from the needle, these sensors will detect significantly different flow or vibrations. A controller can then cease therapy, alert a caregiver, or sound an alarm. | 04-02-2009 |
20090088613 | CONTINUITY CIRCUITS FOR DETECTING ACCESS DISCONNECTION - A monitor for an extracorporeal therapy access site is disclosed. The monitor includes a bandage atop or adjacent the access site and a sensor for monitoring the bandage. The bandage includes a layer of polymer that expands when wetted with blood. The expansion causes a break in continuity of the sensor, or in an alternate embodiment, causes a sensor to cease detecting a target. When the break occurs, the control circuit monitoring the bandage sends a signal that a break has occurred, and a remote monitor then takes appropriate action, such as ceasing therapy, sending an alert, or sounding an alarm. In another embodiment, connecting wires in a continuity circuit are held apart by a polymer that dissolves when contacted by blood. If a leak occurs and a small portion of the polymer dissolves, the wires make contact, thus detecting a blood leak. | 04-02-2009 |
20090099427 | MICRONEEDLE ARRAY WITH DIVERSE NEEDLE CONFIGURATIONS - The invention relates to a surface penetration device, a method to use the device, and an analyte monitor. Embodiments of the surface penetration device include a substrate with first and second surfaces, and first and second tissue piercing elements, the elements differing in configuration, but each associated with the first surface of the substrate. At least some of the tissue piercing elements have a distal and a proximal opening and a lumen extending between the openings. The proximal openings are in fluid communication with an opening in the second surface of the substrate. Embodiments of the analyte monitor include the features of the penetration device plus an analyte sensor that detects an analyte in a fluid. Embodiments of the method of penetrating tissue include providing a surface penetration device and urging the surface penetration device against a tissue surface until some of the first and second tissue piercing elements penetrate the tissue surface. | 04-16-2009 |
20090105562 | SYSTEM AND METHODS FOR SCREENING OR ANALYZING TARGETS - The present invention relates to the system and methods for screening or analyzing targets. | 04-23-2009 |
20090105563 | BIOSENSOR AND COMPONENT CONCENTRATION MEASURING APPARATUS - An object of the invention is to provide a component concentration measuring apparatus by blood sampling by laser perforating, capable of preventing leak of an abnormal odor generated during laser perforating, and improving user's convenience. In a component concentration measuring apparatus of the invention, a slide sheet | 04-23-2009 |
20090131768 | ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system. | 05-21-2009 |
20090131769 | ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system. | 05-21-2009 |
20090137884 | METHODS AND APPARATUS FOR REPEATED ISCHEMIC CONDITIONING TREATMENT OF HYPERTENSION AND OTHER MEDICAL CONDITIONS - Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning. | 05-28-2009 |
20090143654 | BIOLOGICAL MEASUREMENT SYSTEM - This invention measures cerebral blood volume changes to evaluate, from properties of low-frequency components of such changes and heart rate changes calculated by analysis, a distribution of cerebral blood vessel hardness and its with-time change to thereby estimate and display diseased and dangerous portions based on the evaluation. Briefly, the above-noted object is attainable by a biological measurement system having a cerebral blood volume measurement unit which measures a regional cerebral blood volume of a body under test, an analyzer unit that analyzes a signal measured by the cerebral blood volume measurement unit, an extraction unit for extracting, based on an output of the analysis unit, information concerning a regional cerebral blood vessel state of the test body, and a display unit which displays a measurement result of the cerebral blood volume measurement unit, an analysis result of the analyzer unit or an extraction result of the extraction unit. | 06-04-2009 |
20090149725 | Integrated fluid analyte meter system - An integrated meter system for determining information related to an analyte of a fluid sample includes a meter including a housing and a plurality of test sensors. Each of the plurality of test sensors includes a penetrating member, a testing portion, and a channel. The channel is adapted to receive the fluid sample. The test sensors are removably located within the housing. At least one of the test sensors is removably connected to an adjacent test sensor. The integrated meter system also includes a test-sensor advancement mechanism that is configured to advance the test sensors. | 06-11-2009 |
20090156911 | LOW DRAW VOLUME ANALYTE DETECTION SYSTEMS - Systems and methods for determining the concentration of an analyte in a sample such as bodily fluid are disclosed. Systems and methods disclosed herein comprise reducing the volume of sample withdrawn from the source of biological fluid. Low draw volume systems can be implemented using small inner diameter tube, valves and one or more sensors, for example. A method for calibrating a measurement of an analyte in a fluid sample for dilution of the fluid sample is also disclosed. | 06-18-2009 |
20090187083 | CATHETER - A catheter and associated method for taking a plurality of samples from within a length of a blood vessel. The catheter includes an elongate central body arranged to be inserted into and positioned along a central region of a blood vessel. A plurality of collection areas are defined along the elongate central body for collecting samples at the central region of the blood vessel. A plurality of mixers are provided radially outwardly of the elongate central body and arranged to create a flow of blood from a boundary layer at a wall of the blood vessel to the elongate central body. This enables the collection areas to collect samples from the boundary layer. | 07-23-2009 |
20090216094 | Method of deriving a quantitative measure of a degree of calcification of an aorta - A method of deriving a quantitative measure of a degree of calcification of a blood vessel such as an aorta by processing an image such as an X-ray image of at least a part of the blood vessel containing said calcification comprises: taking a starting set of digital data representative of an image of at least part of a blood vessel containing a calcification set against a background; estimating the boundary of the calcification; using inpainting to replace digital data in said starting set representing the calcification with data extrapolating the boundary of the background to extend over the area of calcification, and so generating an inpainted set of digital data; and computing the difference between the starting set of digital data and the inpainted set of digital data to obtain a quantitative measure of the degree of calcification of the blood vessel. | 08-27-2009 |
20090221885 | Optical Window Assembly for Implantable Medical Device - Embodiments of the invention are related to optical window assemblies for implantable medical devices, amongst other things. In an embodiment, the invention includes an optical window assembly for a medical device. The assembly can include a ferrule defining an aperture and a spacer ring disposed within the aperture. The assembly can also include an optical window coupled to the metal ferrule and the spacer ring. In an embodiment, the invention includes an implantable medical device including a housing and an optical window assembly coupled to the housing. In an embodiment, the invention can include a method of manufacturing a medical device. The method can include brazing a spacer ring to a metal ferrule, coupling an optical window to the spacer ring and the metal ferrule with a bonding glass material, depositing a chemical sensing element over the optical window, and coupling a porous cover layer to the spacer ring and the ferrule with an adhesive. Other embodiments are also included herein. | 09-03-2009 |
20090240121 | Intravascular sensor and insertion set combination - An intravascular sensor assembly insertable into an intravenous catheter, the sensor assembly includes a sheath having a sheath proximal end and a sheath distal end wherein an outer diameter of the sheath is sized to be substantially equal to the outer diameter of an insertion needle of the intravenous catheter, a hub sealingly connected to the sheath proximal end, the hub adapted for removably coupling to the intravenous catheter, a sensor disposed within the sheath, the sensor having a sensor shank with a shank distal end and a shank proximal end, a plurality of sensor elements including a working electrode with a reagent matrix disposed thereon, the reagent matrix comprising an enzyme capable of catalyzing a reaction involving a substrate for the enzyme and a reference electrode, the plurality of sensor elements disposed adjacent the shank distal end, a plurality of connector pads disposed at the shank proximal end where the plurality of connector pads are contained within the hub and the plurality of sensor elements are exposed adjacent the sheath distal end, and a plurality of elongated conductive elements where each of the plurality of conductive elements electrically couples one of the plurality of sensor elements to one of the plurality of connector pads, and a cable electrically coupled to the plurality of connector pads. | 09-24-2009 |
20090240122 | INTRAJUGULAR CATHETER - A catheter for insertion into a vascular system of a patient and for directing fluid flow includes a catheter body having a longitudinal axis and longitudinally spaced proximal and distal catheter ends with an intermediate catheter portion defined therebetween. An intermediate catheter outlet in the catheter body is located in the intermediate catheter portion and is spaced longitudinally from the proximal and distal catheter ends. A first lumen is defined within the catheter body and has longitudinally spaced proximal and distal first lumen ends with a reversing bend located therebetween, the first lumen providing fluid communication between the proximal catheter end and the intermediate catheter outlet. The reversing bend is located longitudinally between the intermediate catheter outlet and the distal catheter end. The reversing bend directs fluid flow to turn approximately 180° as the fluid flows through the first lumen. A method of using the catheter is also described. | 09-24-2009 |
20090247838 | ANALYTE TESTING DEVICE - The present invention is a testing device for testing analyte levels in bodily fluids. The testing device comprises memory ( | 10-01-2009 |
20090264717 | ANALYTE METER PROTECTORS AND METHODS - Analyte meter protectors, meters that include the same, and methods. | 10-22-2009 |
20090270696 | ANALYTE METER PROTECTORS AND METHODS - Analyte meter protectors, meters that include the same, and methods. | 10-29-2009 |
20090270697 | ANALYTE METER PROTECTORS AND METHODS - Analyte meter protectors, meters that include the same, and methods. | 10-29-2009 |
20090287069 | METHODS AND APPARATUS FOR REPEATED ISCHEMIC CONDITIONING TREATMENT OF HYPERTENSION AND OTHER MEDICAL CONDITIONS - Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning. | 11-19-2009 |
20090292183 | BIOLOGICAL INFORMATION, ACQUISITION METHOD AND INSTRUMENT, AND PHYSIOLOGICALLY-ACTIVE SUBSTANCE MEASUREMENT METHOD AND INSTRUMENT - A biological information acquisition method for acquiring information on a living body on a basis of a quantified value of a physiologically active substance originated from the living body, includes a step of collecting the physiologically active substance from a body surface of the living body. | 11-26-2009 |
20090292184 | Sensor Inserter Assembly - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion. | 11-26-2009 |
20090292185 | Sensor Inserter Assembly - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion. | 11-26-2009 |
20090312614 | Transdermal Analyte Sensor Assembly and Methods of Using the Same - A transdermal test sensor assembly adapted to determine an analyte concentration of a fluid sample is disclosed. The assembly comprises a sensor support including at least one reservoir adapted to hold a liquid. The assembly further comprises a test sensor being coupled to the sensor support. The test sensor forms at least one aperture therein. At least a portion of the at least one aperture is adjacent to the at least one reservoir. The assembly further comprises a hydrogel composition positioned on the test sensor. The hydrogel composition is linked to the at least one reservoir via the at least one aperture. | 12-17-2009 |
20090318784 | Devices and Methods for Detecting B-Haematin and Haemozoin - In the application, the change in the magnetic state of the haemoglobin caused by the malarial infection is exploited by detecting suitable properties of haemozoin which are dependent on the application of a magnetic field. FIG. | 12-24-2009 |
20100010323 | Temperature-compensated in-vivo sensor - A reagent matrix composition disposed on an electrically conductive electrode to form an in-vivo sensor for a predefined analyte includes a first hydrogel layer containing an enzyme that is a substrate for the analyte adjacent the electrically conductive electrode and a composite membrane layer disposed onto the first hydrogel layer where the composite layer includes a membrane hydrogel containing a plurality of microspheres. The plurality of microspheres is made of a material having no or little permeability to the analyte and a substantially high permeability to oxygen. | 01-14-2010 |
20100010324 | SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk. | 01-14-2010 |
20100016687 | SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk. | 01-21-2010 |
20100022854 | Implantable Chip Medical Diagnostic Device for Bodily Fluids - An implantable microchip that is attached to a source of bodily fluids such as a vein, capillary, small artery or other fluid source such as lymph fluid or urine where the fluid flows through the microchip. The microchip can contain a micro-laboratory with reagent sources and micro-canal test chambers. The microchip can contain a readout mechanism where test data is command and/or readout to an external unit. Test results can be detected with an on-chip fluorescence or light detector or an external detector. | 01-28-2010 |
20100022855 | SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk. | 01-28-2010 |
20100030037 | BLOOD INSPECTION DEVICE - A blood inspection device capable of separately discharging a sensor and a filter by using single discharge means. The blood inspection device has a housing ( | 02-04-2010 |
20100030038 | SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk. | 02-04-2010 |
20100049013 | ANALYTE-TESTING DEVICE - A device adapted to determine an analyte concentration of a fluid sample using a test sensor. The device comprises a display adapted to display information to a user. The device further comprises at least one user-interface mechanism adapted to allow the user to interact with the device. The device further comprises a body portion including at least one opening formed therein, the at least one opening being of sufficient size to receive the test sensor. The device further comprises a memory adapted to store a plurality of stored analyte concentrations. The device further comprises a processing feature adapted to inhibit the stored analyte concentrations from being displayed on the display. | 02-25-2010 |
20100049014 | Sensor Inserter Assembly - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion. | 02-25-2010 |
20100056885 | IMPLANTABLE BIOSENSOR DEVICES FOR MONITORING CARDIAC MARKER MOLECULES - An implantable biosensor system is disclosed for determining levels of cardiac markers in a patient to aid in the diagnosis, determination of the severity and management of cardiovascular diseases. The sensor includes nanowire sensor elements having a biological recognition element attached to a nanowire transducer that specifically binds to the cardiac marker being measured. Each of the sensor elements is associated with a protective member that prevents the sensor element from interacting with the surrounding environment. At a selected time, the protective member may be disabled, thereby allowing the sensor element to begin sensing signals within a living body. | 03-04-2010 |
20100069726 | COMPOSITIONS AND METHODS FOR RAPID ONE-STEP DIAGNOSIS - Devices for fast easy monitoring of analyte levels, disease, or other physiological changes are provided. In some cases, the devices may include particles or the like that can be placed and read at the site of detection, typically on or in the skin or mucosa. In one embodiment, the particles may include anisotropic particles. Typically the devices will typically provide a visual colorimetic signal, but other signals are possible, such as smell, taste (e.g., release of food acceptable flavor), or tactile (e.g., shape change). The devices are preferably single use, disposable devices, although some may be able to provide multiple readings over a period of time. These devices may be used with any patient and are particularly useful for pediatric and elderly patients, as well as for the military, and people without health insurance. The devices can be used to assess when intervention may be required without expensive testing at a physician's office, or simply for routine maintenance of those who are concerned about their health. | 03-18-2010 |
20100076280 | Health Monitor - Methods and devices to detect analyte in body fluid are provided. Embodiments include enhanced analyte monitoring devices and systems. | 03-25-2010 |
20100081895 | WIRELESS MEDICAL TELEMETRY SYSTEM AND METHODS USING RADIO FREQUENCY ENERGIZED BIOSENSORS - A system is provided that furnishes physiological or biomechanical parameters from sensors placed upon or within a subject. The system comprises radio frequency energized biosensor (RFEB) devices that are powered by and communicate with an external receiver and monitoring apparatus. One embodiment of the system provides for infant monitoring in a crib utilizing RFEB devices incorporated into a dermal patch. Said patch communicates with a receiver suspended above the crib and alerts of early warning signs of sudden infant death syndrome (SIDS) or other physiologic abnormalities. Another embodiment comprises implantable RFEB devices that relay information related to the condition of an internal tissue, organ, or cavity to an external receiver, monitor, and recorder. Other embodiments include wearable sensors for detecting a subject attempting to get out of bed, dislodge medical equipment, or stray from a given location. | 04-01-2010 |
20100081896 | GASTRIC INSERTION CONFIRMATION DEVICE AND METHOD OF USE - A confirmation device. The device includes a housing having a central passageway and a secondary passageway extending from the central passageway. The device also has a negative pressure member in communication with the secondary passageway and an indicator mechanism in fluid communication with the secondary passageway for visually indicating the presence of one or more components within the secondary passageway. The negative pressure member is operable to draw fluid across the indicator mechanism. | 04-01-2010 |
20100087716 | Portable microchip module for instantaneous analysis of bodily fluids - A portable microchip substrate supported in a receptacle having one end connected to a catheter inserted in the body of a patient. The other end of the receptacle is connected to a needleless syringe for drawing a bodily fluid sample (e.g. blood) through the receptacle and into contact with the substrate. The substrate is adapted to instantaneously perform diagnostic tests on the fluid sample in contact therewith within the receptacle. A communication device on the receptacle transmits signals to an analyzer which includes a display for indicating various diagnostic characteristics of the bodily fluid sample in real time. The receptacle and the substrate may be cleaned (sterilized) for re-use or may be disposed of after a one-time use. In an alternatively preferred embodiment, the substrate and/or communication device are directly carried on and supported by the insertable catheter. | 04-08-2010 |
20100094105 | PIEZOELECTRIC TRANSDUCER - A miniature piezoelectric transducer element is provided, comprising; (a) a cell element having a cavity; (b) a flexible piezoelectric layer attached to the cell member, the piezoelectric layer having an external surface and an internal surface, the piezoelectric layer featuring such dimensions so as to enable fluctuations thereof at its resonance frequency upon impinging of an external acoustic wave; and (c) a first electrode attached to the external surface and a second electrode attached to the internal surface of the piezoelectric layer. At least one of the electrodes may be specifically shaped so as to provide a maximal electrical output, wherein the electrical output may be current, voltage or power. A preferred shape of the electrodes includes two cores interconnected by a connecting member. The transducer element may function as a transmitter. | 04-15-2010 |
20100113896 | DIAGNOSTIC DEVICE WITH DISPLAY MODULE AND LEVERAGED COMPONENT CONNECTIONS - The present invention provides an innovative means for efficient and secure component assembly and for ensuring secure electrical connections in a small diagnostics device where available space for fasteners is limited. In one embodiment, principles of leverage are employed to produce a force at a location where space is available. The force is transferred to a different location of the assembly where it is used to maintain secure connections between components. | 05-06-2010 |
20100121162 | CHILD-FRIENDLY ANALYTE MEASUREMENT INSTRUMENT - Embodiments of a child-friendly analyte measurement system are provided for detecting at least one analyte in a bodily fluid. A measurement system comprises at least one measurement instrument for detecting the analyte in the bodily fluid, such as a commercially available measurement instrument. The measurement instrument is configured as a portable hand-held instrument and has a housing with at least one display element. Furthermore, the measurement system comprises a toy, in particular a figurine or a toy animal. The toy has at least one receptacle for reversibly holding the measurement instrument, which receptacle is configured such that if the measurement instrument is held by the receptacle, the display element is accessible, at least in part. The measurement instrument is configured such that it can be used both in the measurement system and also, optionally, independently of the toy. Further aspects include a kit, a method, and the toy for the provided measurement system. | 05-13-2010 |
20100152554 | MONITORING DEVICE - Provided is a small sized, portable monitoring device capable of determining an analyte under investigation and having a system and method for providing compliance information to a user of his management of a disease, and for easily navigating a menu structure by means of manual control(s). Further provided is the provision of feedback to the user in form of a disease management information to be easily understood by a user such as the further described COMPLIANCE WINDOW or the INDICATOR CATEGORIES. The user interface can be used in connection with a glucose diagnostic device, a coagulation diagnostic device, immunoassay diagnostic device, and other monitoring devices such as an blood pressure monitor or a pedometer. | 06-17-2010 |
20100152555 | METHOD AND DEVICE FOR MICRODIALYSIS SAMPLING - The microdialysis technique and device of the present invention can be used to study metabolic aspects of human and animal organs. When a microdialysis catheter is for example placed into the substance of a beating heart, there is always concern for problems with the catheter position. Further, there is always a risk for damage to heart tissue as well as to the catheter. The present invention is designed to avoid such damages, and a study has confirmed that data obtained from the epicardial probe of the present invention reflects the state of the myocardial metabolism. In anesthetized normoventilated pigs (n=20), a sternotomy was performed and a Gore-tex suture snare was placed around a branch of the left anterior descending (LAD) artery. One microdialysis probe was inserted in the myocardial tissue supplied by the snared LAD branch. Another microdialysis probe was placed on the epicardial surface above the myocardial probe. The protocol included four, ten minute ischemic periods (intervention group) followed by a forty minute ischemic period. The control group was only exposed to a forty minute ischemic period. It was possible to place the microdialysis probes of the present invention on the epicardial surface, and to recover samples reflecting the myocardial metabolic state of the heart. It was also possible to measure rapid changes in concentrations especially for lactate, where ischemia periods as short as ten minutes resulted in detectable increases. A similar pattern was found when analysing glucose and glycerol concentrations in paired samples. Data obtained from the device and method of the present invention, placed on the epicardial surface showed a similar pattern compared to data from a standard probe placed in the myocardium. Thus, the epicedial application of the present invention is useful for perioperative monitoring during cardiac surgery. | 06-17-2010 |
20100152556 | APPARATUS FOR MEASURING BIOLOGICAL INFORMATION AND EARPHONE HAVING THE SAME - Disclosed is an apparatus for measuring biological information and an earphone having the same for contacting with a uniform pressure a user body part using an elastic member. The apparatus includes a first housing; a second housing foldably connected with the first housing; a third housing foldably connected with the second housing and provided with a sensor for measuring the biological information; a plurality of joint parts for connecting the housings to be folded or unfolded to each other; one or more locking parts for restraining or releasing the housings to be folded or unfolded to each other; and the elastic member for applying the same pressure to make the sensor contact with the user's body by enabling the respective housings to be folded or unfolded using a stress-strain. | 06-17-2010 |
20100152557 | APPARATUS FOR MEASURING BIOLOGICAL INFORMATION AND EARPHONE HAVING THE SAME - Disclosed is an apparatus for measuring biological information and an earphone having the same for contacting with a uniform pressure a user body part using an elastic member. The apparatus includes a first housing; a second housing foldably connected with the first housing; a third housing foldably connected with the second housing and provided with a sensor for measuring the biological information; a plurality of joint parts for connecting the housings to be folded or unfolded to each other; one or more locking parts for restraining or releasing the housings to be folded or unfolded to each other; and the elastic member for applying the same pressure to make the sensor contact with the user's body by enabling the respective housings to be folded or unfolded using a stress-strain. | 06-17-2010 |
20100160748 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 06-24-2010 |
20100168534 | BLOOD INSPECTION DEVICE - A blood inspection device using laser as puncture means. The blood inspection device has an electric power source control circuit for controlling electric power supply of an electric power source section including an electric power source for driving an electric circuit for measurement and also including an electric power source for driving a laser emission device. When a battery is used as the electric power source, the circuit measures the remaining level and voltage of the battery to control the power source so that electric power shortage does not disenable measurement. | 07-01-2010 |
20100168535 | METHODS AND APPARATUSES RELATED TO BLOOD ANALYTE MEASUREMENT SYSTEM - The present invention relates to a blood analyte measurement system for the procurement of blood samples for measurement of blood properties such as analyte concentration or analyte presence. A blood access system can be coupled with a measurement system such as an electrochemical sensor, and can also be used with other measurement modalities. Embodiments of the present invention can facilitate accurate measurement of blood glucose by the clinician in a sterile manner. Embodiments of the present invention can also enable the calibration of the sensor at one or more calibration points. One desired analyte of measurement is glucose for the effective implementation of glycemic control protocols. Embodiments of the present invention can also be used for the measurement of other analytes such as arterial blood gases, lactate, hemoglobin, potassium and urea. Additionally, embodiments of the present invention can function effectively on a variety of blood access points and specifically enables glucose monitoring in an existing arterial line that is already in place for hemodynamic monitoring. The present invention does not consume a significant amount of blood. Some embodiments of the present invention can re-infuse the blood into the patient, which can facilitate operation of the system in a sterile manner. | 07-01-2010 |
20100174156 | Method of Detecting and Measuring Hydration Imbalance - Hydration imbalance can adversely affect individuals who work in adverse environments or suffer from hydration related conditions. Rapid and continuous monitoring of at least one saliva component allows monitoring of an individual's hydration level. Interceptive preventive measures based on the detection and measurement of saliva osmolality/osmolarity at the early stages of hydration imbalance negates potential health hazards and death. | 07-08-2010 |
20100174157 | TRANSCUTANEOUS ANALYTE SENSOR - The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. | 07-08-2010 |
20100174158 | TRANSCUTANEOUS ANALYTE SENSOR - The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. | 07-08-2010 |
20100179397 | Device And Method For Continuous Monitoring Of A Chemical Parameter Of An Individual - A device according to an embodiment of the invention includes a microdialysis catheter having an inlet and an outlet, a pump, and a flow-through monitor. The monitor is configured to analyze dialysate present in perfusion fluid exiting the microdialysis catheter. A chemical parameter may thereby be continuously monitored. | 07-15-2010 |
20100179398 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 07-15-2010 |
20100179399 | SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA - Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor. | 07-15-2010 |
20100179400 | SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk. | 07-15-2010 |
20100179401 | INTEGRATED RECEIVER FOR CONTINUOUS ANALYTE SENSOR - A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface. | 07-15-2010 |
20100179402 | SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA FOR SENSOR CALIBRATION - Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor. | 07-15-2010 |
20100185065 | SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA - Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor. | 07-22-2010 |
20100191078 | ENERGY SUPPLY FOR FLUID DISPENSING DEVICE - Disclosed is a portable fluid dispensing device for infusing a fluid into the body of a user and/or for sensing an analyte within the body. The device includes at least one housing to retain a source of energy to energize the device, the source of energy comprising at least one electrochemical cell to produce electrical energy upon exposure of the cell to air, and a seal to prevent exposure of the at least one cell to air when the source of energy is not in use and to enable exposure of the at least one cell to air prior to energizing the device with the source of energy. The at least one housing includes an opening to provide access to the seal to enable actuation of the seal to control exposure of the at least one cell to air. | 07-29-2010 |
20100234702 | DEVICE FOR ACCURATELY MEASURING CONCENTRATION OF COMPONENT IN BLOOD AND CONTROL METHOD OF THE DEVICE - A measurement device includes an electronic component device, a perspiration acceleration device, and a perspiration collection device. The perspiration acceleration device or the perspiration collection device is removably coupled to the electronic component device. The electronic component device is attached to a measurement site with a belt. A perspiration accelerating performance is made with respect to the measurement site with the perspiration acceleration device coupled to the electronic component device, and thereafter, the perspiration acceleration device is replaced with the perspiration collection device with the electronic component device attached to the measurement site, and the perspiration collection and measurement computation performance are made. | 09-16-2010 |
20100240969 | Systems and Methods for Transdermal Secretion Detection - Various embodiments of the present invention provide systems and methods for detecting chemicals. As an example, a system is disclosed that includes a chemical sensor, a processor, and a computer readable medium. The computer readable medium includes instructions executable by the processor to: receive a plurality of outputs from the chemical sensor; calculate a baseline value using the plurality of outputs from the chemical sensor; and report an event when the baseline value is exceeded. | 09-23-2010 |
20100240970 | METHOD FOR AN IN VIVO MEASUREMENT USING A DEVICE IMPLANTED IN A PATIENT, AND CORRESPONDING DEVICE - An embodiment of the present invention relates to a device, which can be implanted into a patient, for an in vivo measurement. In an embodiment, the device includes a catheter for guiding a sample of the patient town analysis unit in the device. A measurement result is determined in the analysis unit by analyzing the sample with the aid of a reagent. In an embodiment, the device furthermore includes an interchange chamber, with the aid of which the reagent can be removed from the device or can be inserted into the device. The interchange chamber has a connector allowing removal or insertion of the reagent while the device is implanted. | 09-23-2010 |
20100274107 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS - Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species. | 10-28-2010 |
20100274108 | Method and Apparatus for Providing Rechargeable Power in Data Monitoring and Management Systems - Method and apparatus for providing a disposable power supply source integrated into the housing of the transmitter unit mount that is placed on the skin of the patient, and configured to receive the transmitter unit is disclosed. The transmitter unit mount is configured to be disposable with the analyte sensor so that power supply providing power to the transmitter unit is also replaced. The transmitter unit may include a rechargeable battery that is recharged by the power supply unit of the transmitter unit mount when the transmitter is mounted to the transmitter unit mount. Other energy store configurations including single large capacitor (supercap) or a capacitor and DC/DC converter configurations are disclosed. | 10-28-2010 |
20100280341 | POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS - Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species. | 11-04-2010 |
20100298670 | ELECTROLYTE MONITORING USING IMPLANTED CARDIAC RHYTHM MANAGEMENT DEVICE - A method for diagnosing an electrolyte level with a cardiac rhythm management device includes recording intra-cardiac electrograms from multiple sites. The method determines the electrolyte level based upon a comparative analysis of intra-cardiac electrograms recorded from at least two of the sites. The electrolyte level can be quantified based upon a general model, or a patient specific model. | 11-25-2010 |
20100298671 | METHOD FOR ANALYZING ANALYTE IN TISSUE FLUID, ANALYZER FOR ANALYZING ANALYTE IN TISSUE FLUID, CARTRIDGE FOR ANALYZING ANALYTE IN TISSUE FLUID, AND KIT FOR ANALYZING ANALYTE IN TISSUE FLUID - A method for analyzing an analyte in tissue fluid is disclosed. The method comprises: placing a collecting member in contact with the skin of a subject, wherein the collecting member is configured to collect and retain tissue fluid containing the analyte from the subject; collecting tissue fluid from the subject into the collecting member; detaching the collecting member from the skin of the subject; causing the analyte in the tissue fluid collected by the collecting member to diffuse in a liquid by supplying the collecting member with the liquid; and detecting the analyte diffused in the liquid. | 11-25-2010 |
20100305416 | NON-INVASIVE PRESSURED PROBING DEVICE - A non-invasive probing device wearable over a skin of a patient for monitoring the patient is provided. The probing device includes a physiological probe having a sensing interface, and a housing for housing the probe. The housing includes a body having a skin-side surface for lying next to the skin of the patient and a fixed or resilient protruding member fixedly or resiliently protruding from the skin-side surface. The protruding member houses the sensing interface. The device also includes attachment means for attaching the device to the skin of the patient. In the case of a resilient protruding member, the device may include a resilient mechanism for biasing the resilient protruding member against the body. Also in the case of a resilient protruding member, the device may include a protective cover for protecting the device against unwanted external influences. | 12-02-2010 |
20100317935 | TEST MEDIA CASSETTE FOR BODILY FLUID TESTING DEVICE - A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media. | 12-16-2010 |
20100331634 | HYDROGEL IMPLANT FOR SENSING METABOLITES IN BODY TISSUE - An implant ( | 12-30-2010 |
20100331635 | Finger-Clipped Oximeter with Finger Pressed Plate - The present invention discloses a finger-clipped oximeter comprising: an upper case ( | 12-30-2010 |
20110004077 | CONTAINER CONTAINING REFERENCE SOLUTION - The present disclosure provides a container containing reference solution for clinical chemistry, whereby the container includes a closure part-covered outlet at which reference solution can be removed by puncturing with a puncturing element. The disclosure further provides a wick that is soaked with the reference solution and arranged in the container to extend from the outlet and such that a majority of its length extends into an interior space of the container. | 01-06-2011 |
20110004078 | BLOOD TESTING DEVICE - A blood testing device in which a blood sensor does not contaminate a piercing section when discarded. The blood testing device ( | 01-06-2011 |
20110009717 | BLOOD SAMPLING DEVICE - A blood sampling device useful for collecting a blood sample from a separate vascular access device is described herein. The blood sampling device includes a body shaped and sized for partial insertion into a separate vascular access device. The body includes a reservoir defined within the body, which has an internal volume sufficient to contain enough blood for use in a diagnostic blood test. The body also includes a gas permeable vent disposed on the body, in which the gas permeable vent is in gaseous communication with the reservoir. When connected to a separate vascular access device the blood sampling device collects a blood sample as blood flows into the reservoir from the separate vascular access device and as gases pass out the reservoir via the gas permeable vent. | 01-13-2011 |
20110034785 | Biopolymer resistant devices using coatings with surface energy gradient - A medical device or analytical device comprising a fluid-impervious surface comprising a base surface, at least one distinct region of the base surface covered by a mixed monolayer film, the mixed monolayer film comprising a species having a functional group M1 and a species having a functional group M2 where M1 and M2 have different surface energies, the mixed monolayer forming a surface energy gradient wherein at least one of the species used to form the monolayer on the surface comprises a biopolymer-resistant domain. | 02-10-2011 |
20110040160 | ANALYSIS DEVICE HAVING A DISCARDING MECHANISM - An analyzing device which fits an analyzing instrument | 02-17-2011 |
20110046453 | TEST STRIP WITH A SHAPED TIP FOR SKIN STRAIGHTENING - The test strip stabilizes skin prior to incision by a lancet tip. The innovative test strip includes a pair of skin contacting tabs that apply pressure linearly to the skin to stretch the skin taut. Beneficially an incision by a lancet tip to an accurate depth can be formed on the taut skin. Moreover, pressure from the tabs is applied linearly to the skin which results in a higher ratio of pressure to surface that can be reached as compared to applying pressure laminarily to skin. Some manufacturing techniques of the skin contacting tabs include cutting or stamping through all of the layers and test area of the test strip to form these tabs. These techniques increase the manufacturing efficiency and cost savings associated with test strips and integrated lancet testing devices. Contamination from other sampling events is eliminated since the test strips are disposed of after each use. | 02-24-2011 |
20110046454 | INJECTION APPARATUS - An injection apparatus ( | 02-24-2011 |
20110046455 | METHODS AND DEVICES FOR EXAMINING A PARTICULAR TISSUE VOLUME IN A BODY, AND A METHOD AND A DEVICE FOR SEGMENTING THE PARTICULAR TISSUE VOLUME - A tip of an elongate device is navigated into a particular tissue volume in order to examine the particular tissue volume in a body and part of the tissue volume is analyzed in real-time by way of a biosensor. In at least one embodiment, in the process, either the biosensor can be arranged on the tip of the device or the device includes a catheter, by which a substance to be analyzed is transported out of the tissue volume from the tip to the biosensor arranged at the proximal end of the catheter. | 02-24-2011 |
20110046456 | Assembly Comprising Inserter, Cannula Part and Base Part - The invention relates to an assembly comprising—an inserter ( | 02-24-2011 |
20110046457 | MULTILUMEN CATHETER - A multilumen catheter having tubings extending into lumens within the catheter. The lumens may be used for blood, drugs or other medicants. The lumens may also be used for sensors. The junction element, external to the patient, connects the tubings to the lumens. The tubings, also external to the patient, connect to infusion members, to which one or more infusion systems may be connected to deliver blood, drugs and other medicants to the patient. A sensor having a sensing element may extend through the sensor lumen and be positioned internal to the patient for physiological parameter sensing. An external portion of the sensor may be connected to associated electronics to provide automatic monitoring of the physiological parameters and automatic delivery and control of the infusants. Also, a central line catheter for delivering fluids directly into a main artery or vein near the heart, which contains a first lumen to deliver a fluid through the central line catheter and a second lumen containing a sensor capable indicating a characteristic level in blood. The first lumen delivers the fluid downstream of the sensor to prevent any interference between the fluid delivery and the sensor readings. In other versions, the central line catheter can have additional lumens for additional purposes. In addition, the central line catheter can further include a flush sleeve to remove debris around the sensor. | 02-24-2011 |
20110046458 | DEVICE FOR DETECTING A MEDICAL CONDITION OR DISEASE - The invention relates to a capsule or chip or sensor comprising a marker/detector and signalling device/method associated with the development of a medical condition/disease and to its use. This In Situ Lab On a Chip Signalling device (ISLOGS device) is used for detecting a medical condition/disease in situ or in vivo (inside the body), for example by swallowing it for testing in the digestive tract or by putting it into the vagina, mouth or nose. All reactions takes place in the body and when the test result is positive the device will notify the subject by colorizing the tested body fluid or biomaterial (for example faeces, urine or saliva) or the device itself. The detection is made outside of the body when the biomaterial or ISLOCS device has left the body. | 02-24-2011 |
20110054273 | HEALTH CARE DEVICE - Embodiments described herein relate to health monitoring apparatuses, systems and methods that allow a user to passively monitor her/his health. Embodiments include acquiring chemical substances from a subject's skin (e.g., in sweat and/or sweat vapor or oil excretions) using a sample capture system located on a mounting portion in a fixed location. Embodiments also include analyzing chemical substance(s) acquiring from the subject's skin to generate raw data. Embodiments further include analyzing the raw data to generate health status data for a particular subject. | 03-03-2011 |
20110054274 | DEVICE AND METHOD FOR WITHDRAWING BODY FLUID - The invention relates to a device for removing body fluid with a puncture element that can puncture the skin of a body part. The device includes a housing structure for body fluids obtained from the skin puncture and a puncture drive for a back and forth movement of the puncture element. The duration of withdrawal movement is longer than the duration of the forward movement. The puncture drive is designed to withdraw the puncture element in a first withdrawal phase of the withdrawal movement with a maximum withdrawal speed of more than 0.02 m/s. A second retraction phase follows the first retraction phase. Body fluid is collected during the second retraction phase, which has a duration of between 0.3 and 0.8 seconds and/or a retraction speed of between 0.6 and 2 mm/s. | 03-03-2011 |
20110054275 | Mounting Unit Having a Sensor and Associated Circuitry - Disclosed herein is a mounting unit assembly that includes a mounting unit and a sensor integrally formed with the mounting unit such that the mounting unit and sensor form a single unit. | 03-03-2011 |
20110060196 | Flexible Mounting Unit and Cover for a Medical Device - Generally, embodiments of the present disclosure are directed to an adhesive mounting unit that is formed from a nonwoven polymeric material that is breathable, flexible, waterproof and durable. Additionally, the adhesive mounting unit of the present disclosure includes a retention mechanism that is insert molded directly into or on the mounting unit such that the mounting unit and retention mechanism form a single unitary structure. | 03-10-2011 |
20110066012 | NEEDLE INSERTION SYSTEMS AND METHODS - A housing may have a needle, plunger, and bias mechanism supported within the housing by a tab configured to retain the plunger in position and to allow the plunger to move under bias force imparted by the bias mechanism to move the needle to an insert position when the tab is removed. A base and a structure may be configured for relative movement there between and may be adapted to be secured to a user with a cannula extending through a body of the structure into the user during use of a medical device. A housing may be adapted to be secured to a user to support a medical device operable with an insertion needle, the housing having a magnifying material for increasing visibility of an injection site. | 03-17-2011 |
20110077477 | SENSORS WITH THROMBORESISTANT COATING - Embodiments of the present invention relate to analyte sensors comprising a heparin benzalkonium antithrombogenic coating, and methods of coating analyte sensors. | 03-31-2011 |
20110077478 | Body fluid sampling module with a continuous compression tissue interface surface - A body fluid sampling device includes a housing, a penetrating member positioned in the housing and a test strip. A compliant front end is coupled to the housing. The compliant front-end includes a rigid member with an interior aperture to receive the body fluid from a wound site. | 03-31-2011 |
20110077479 | Method and System for Providing Basal Profile Modification in Analyte Monitoring and Management Systems - Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed. | 03-31-2011 |
20110092783 | IN VIVO MICRO-INVASIVE INVESTIGATION DEVICE INCLUDING A METAL GUIDE - The invention relates to an analysis device, wherein said system includes at least one metal guide at one end of which is provided at least one series of pits to which are directly coupled reagents specific to a substrate, said end being a perforating one, while the other end is intended for controlling said guide and is optionally associated with a suction system. The guide may be inserted into a protection system that is removable at the level of the functionalised end, up to the micro-analysis and/or micro-sampling site, and/or into a medical instrument having an inner channel in which said guide may slide. The present invention also relates to the use of such a device for making a tool for diagnosing cancer, an inflammation, an infection, a neurodegenerative disease or a graft rejection in a patient, preferably by transparietal delivery. The invention further relates to a method for the ex vivo analysis of a substrate using such a device. | 04-21-2011 |
20110098541 | Method and apparatus for penetrating tissue - These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting. | 04-28-2011 |
20110112384 | Medical system having consumables monitoring - The invention proposes a medical system which comprises a central control unit which is set up to display at least one diagnostic measured value using a display element. The medical system also comprises at least one invasive unit, wherein the invasive unit has at least one invasive consumable. The invasive consumable is set up to invasively intervene in a tissue of a patient. The invasive unit has at least one contactlessly readable electronic identifier for storing at least one piece of information. The central control unit is set up to electronically read the at least one piece of information in the electronic identifier. The central control unit and the invasive unit are functionally independent of one another such that the respective function of the central control unit and of the invasive unit can be performed independently of the presence of the respective other unit. | 05-12-2011 |
20110118568 | ASSISTANCE DEVICE - Disclosed is an assistance device which can be used for the puncture into the skin with a puncture tool having a puncture needle and the measurement of a desired component in the blood with a blood glucose monitoring system equipped with a measurement tool. The assistance device comprises a main body which contacts with the skin and a lid which is connected to the main body in a freely openable and closable manner, wherein one of the main body and the lid has a puncture guide for positioning the puncture needle toward a position on the skin to be punctured with the puncture needle, and the other has a blood collection guide for positioning the measurement tool toward the position on the skin punctured with the puncture needle. | 05-19-2011 |
20110118569 | Advanced Detection of Sepsis - The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or respiration rate) and/or at least one biomarker for the early detection of sepsis in a subject. | 05-19-2011 |
20110124984 | Device for Aliquoting and Filtering Blood - Device for aliquoting and filtering blood, comprising: an element ( | 05-26-2011 |
20110124985 | VISCOSIMETRIC BIOSENSOR FOR MONITORING ANALYTE LEVELS - The invention relates to a viscosimetric sensor for monitoring an analyte level in a patient or in body fluids ex vivo. In particular, the invention relates to a sensor for monitoring analytes, such as glucose levels in a patient. The sensor comprises at least two hermetically closed chambers ( | 05-26-2011 |
20110124986 | Microchip, Blood Analysis System and Blood Analysis Method - A microchip to be installed in a blood analysis system for measuring properties of blood, provided with a plurality of channels through which blood passes, wherein only each of first subset channels among the plurality of channels is provided with a first plurality of barriers for locally changing a direction of blood flow, in a blood flow direction on a wall face demarcating the channels, and among the first plurality of barriers, barriers which are adjacent to each other in the blood flow direction differ in shape from each other. | 05-26-2011 |
20110130637 | PROTEIN PRODUCT FOR MODIFYING CARDIOVASCULAR HEALTH - A composition for use in the treatment or prophylaxis of conditions mediated by endothelial function in mammals is provided. The composition includes a milk protein hydrolysate generated by treating milk or milk whey protein with a proteolytic enzyme having subtilisin or subtilisin-like activity and/or glutamyl endopeptidase or glutamyl endopeptidase-like activity. The composition is useful in the management of vascular conditions. | 06-02-2011 |
20110137139 | POST-OPERATIVE BACTERIA TEST STRIP SPOOL AND METHOD - A method for testing body fluids is disclosed. The method includes providing a media-dispensing apparatus, placing at least the distal opening of the elongated tubular member adjacent body fluid (e.g., near a patient's abdomen) or adjacent a medical device such that a portion of the media strip contacts body fluid or the medical device, and advancing the media strip such that the portion of the media strip that contacted the body fluid or the medical device advances at least through the second lumen. Additionally, the step of cutting the media strip with a cutting instrument is also disclosed. | 06-09-2011 |
20110152641 | DISPOSABLE COVER FOR USE IN AN INCUBATOR FOR PREMATURE INFANTS - The invention refers to a disposable cover for use in an incubator for premature infants comprising a moisture-pervious surface layer and a preferably moisture-impervious back sheet, wherein the total weight of the cover before use is communicated to the caregiver by indication on said cover, a label accompanying said cover or on the package for said cover. The cover may further be provided with a wetness indicator. | 06-23-2011 |
20110152642 | DETECTION OF BUBBLES DURING HEMODYNAMIC MONITORING WHEN PERFORMING AUTOMATED MEASUREMENT OF BLOOD CONSTITUENTS - Example embodiments of the present invention provide methods and apparatuses that enable the detection of bubbles so that hemodynamic performance can be assured following an automated blood analyte measurement. An example apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the blood back into the body. The infusion of at least a portion of the blood back in to the body can be done in a manner to assure that no bubbles of clinical significance are injected into the patient. Additionally an example embodiment can assess for the presence of bubbles in the fluid column that can affect hemodynamic monitoring performance. If a condition exists where hemodynamic monitoring performance cannot be assured, an example embodiment can provide appropriate warning or corrective actions. | 06-23-2011 |
20110152643 | "Band-aid"-type potassium ion (K+) biosensor - Potassium ion (K+) is important in regulating normal cell function in the human body, specifically the heartbeat and the muscle function. It is important to be able to monitor potassium ion concentrations in human fluids. This invention describes a novel concept for a potassium ion biosensor that accurately, rapidly, and efficiently monitors the presence and records the concentration of potassium ions with high specificity, not only in serum and urine, but also in the sweat or even eye fluid. This specific biosensor design utilizes a nanomanufacturing technique, i.e. electrospinning, to produce advanced nano-bio-composites that specifically trace even minute quantities of potassium ions through the use of selective bio-receptors (ionophores) attached to high surface area nanofibers. Electroactive polymers are then employed as transducers to produce an electronic (rather than ionic) output that changes instantly with the change in K+ concentration. Such biosensors may be manufactured in a skin patch configuration. | 06-23-2011 |
20110152644 | PROTECTIVE CONTAINER FOR HOLDING REUSABLE DIAGNOSTIC COMPONENTS - A protective container for holding a reusable control part of a transcutaneous sensor system for detecting at least one analyte in a bodily fluid is disclosed. The control part includes at least one coupling, which has at least one sensor coupling for connection to at least one transcutaneous sensor. The protective container has at least one container housing. The control part can be held in the container housing. The container housing is adapted to shield the control part from environmental influences. The container housing also has at least one connector which can be connected to the coupling and seals the latter in a media-tight fashion. | 06-23-2011 |
20110166431 | TAPE CASSETTE FOR A MEDICAL HANDHELD DEVICE - A tape cassette for a medical handheld device is disclosed as comprising a carrier tape, which carries test fields for assaying a sample of a human or animal bodily fluid and/or lancets as functional elements, a supply chamber, in which a supply section of the carrier tape comprising unused functional elements is positioned, a winding unit, in order to wind up the carrier tape and draw it through a tape exit opening of the chamber, so that the functional elements may be brought sequentially into a usage position. The carrier tape in the tape exit opening is oriented transversely to the supply section positioned in the supply chamber. | 07-07-2011 |
20110172508 | SAMPLING DEVICE INTERFACES - The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device. For example, the device may be mounted or engaged on an external holder, the device may include a port for transporting fluid out of the device, the device may include a window for interrogating a fluid contained within the device, or the like. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like. | 07-14-2011 |
20110178378 | TRANSCUTANEOUS ANALYTE SENSOR - The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. | 07-21-2011 |
20110184258 | Balloon Catheter Analyte Measurement Sensors and Methods for Using the Same - Balloon catheters, assemblies and systems and methods for using them for the continuous in vivo monitoring of one or more selected analytes or other physiological chemistries within a patient using an implantable analyte sensor associated with a balloon catheter are provided. | 07-28-2011 |
20110190603 | Sensor Inserter Having Introducer - A sensor inserter assembly having an introducer configured with one or more holding members to releasably retain a sensor and/or a compressible member. | 08-04-2011 |
20110190604 | Nitric oxide sensors and systems - The present disclosure relates to nitric oxide sensors and systems. | 08-04-2011 |
20110196214 | Fetal Scalp Blood Analyzer - A hand-held analyzer for collecting a sample of blood from the scalp of a fetus and measuring the pH or other blood characteristic of the blood sample. The analyzer includes a probe with a proximal end and a gasket that facilitate a firm and positive placement of the probe against the scalp. The probe includes a capillary tube for collecting blood and an extensible lancet which at rest is positioned within the capillary tube. During operation, the lancet is extended to make an incision in the scalp. The lancet then retreats, and blood flows into the capillary tube. Sensors for measuring pH are in liquid communication with the capillary tube. A display on or near the hand-held analyzer shows a readout of the fetal scalp blood pH or other blood characteristic. Measuring the pH of the fetal scalp blood in utero can provide early detection of acidosis and likely hypoxia. | 08-11-2011 |
20110208020 | System with a reservoir for perfusion management - A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies. | 08-25-2011 |
20110208021 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 08-25-2011 |
20110208022 | DEVICE AND METHODS FOR SAMPLING PROSTATE FLUID - Disclosed are devices and methods to improve sampling of prostate secretions for purposes of diagnoses, staging, assessment of malignant potential, prognosis. | 08-25-2011 |
20110213225 | Medical devices and methods - Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. | 09-01-2011 |
20110230735 | ANALYTE SENSOR APPARATUSES HAVING IMPROVED ELECTRODE CONFIGURATIONS AND METHODS FOR MAKING AND USING THEM - Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes. | 09-22-2011 |
20110230736 | DEVICE AND METHOD FOR DRUG EVALUATION AND LOCAL TREATMENT - Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers ( | 09-22-2011 |
20110230737 | DEVICE AND METHOD FOR EARLY DIAGNOSIS AND PROGNOSIS OF HEALING PROGRESSIONS, IN PARTICULAR FOR BONE INJURIES - The invention relates to a device comprising: i) a sample-receiving unit ( | 09-22-2011 |
20110245634 | Methods, Systems, and Devices for Analyzing Patient Data - Described herein is a method of analyzing an analyte distribution from discrete, quasi-continuous or continuous measurements to determine a glycemic state of a patient in order to understand how often, and for how long, a patient's post-prandial glucose is out of control without requiring laboratory blood test and especially post-prandial levels laboratory analysis. The systems, devices, and methods assist in predicting risk levels of developing diabetes-associated complications. Therefore applicants have recognized also a need for a tool which facilitates stratification of patients for risk of and/or onset of one or more complications having the same HbA1c level. | 10-06-2011 |
20110245635 | PRESSURE REDUCTION MECHANISM, PUNCTURE DEVICE, BLOOD ANALYSIS DEVICE, AND SENSOR MOUNTING MECHANISM - Provided are a decompression mechanism capable of performing a desired pressure reduction by simple operation and having improved operability, a puncture device, a blood analysis device, and a sensor mounting mechanism. A needle puncturing device ( | 10-06-2011 |
20110257493 | BODY FLUID SAMPLING DEVICE - Body fluid sampling device comprising a sampling element having a fluid pathway ( | 10-20-2011 |
20110263952 | INCONTINENCE MANAGEMENT SYSTEM AND DIAPER - An incontinence management system for monitoring wetness in one or more absorbent articles, includes input for receiving one or more sensor signals indicative of a presence of wetness in an absorbent article, processor for processing the one or more sensor signals and for performing an analysis of the signals to characterise wetness events occurring in an absorbent article and user interface for communicating with a user of the system. A mathematical model is used to characterise wetness events, receiving as inputs variables derived from sensor signals and optionally, patient and demographic data. The mathematical model can be configured and/or re-configured utilising observation data obtained while monitoring a patient for wetness. A diaper for use with such as system is also disclosed. | 10-27-2011 |
20110270053 | Intra-Oral Detector and System for Modification of Undesired Behaviors and Methods Thereof - Methods, devices and systems are disclosed for use in detecting a number of substances that may be present, whether constantly or intermittently, in the oral cavity and indicative of specific undesirable and/or unhealthy behaviors. Disclosed devices including detectors that indicate the presence of targeted substances qualitatively or quantitatively, may be secured temporarily, semi-permanently or permanently in the oral cavity employing known dental materials and techniques. The disclosed methods and devices enable constant passive monitoring and therefore may aid in the cessation via a number of positive and negative feedback mechanisms, as well as providing additional diagnostic information to healthcare providers. | 11-03-2011 |
20110270054 | ASSAY FOR POSITIONING A FEEDING TUBE AND METHOD THEREOF - The present invention discloses a bedside or point of care assay for properly positioning a feeding tube in the stomach of a patient based on detecting the presence of a hydrolytic enzyme found in the stomach by an ester substrate which can be impregnated on a pH strip. The application of this test reduces the risk of tube misplacement and the resulting harm to the patient that occurs in the event of tube misplacement. | 11-03-2011 |
20110270055 | MEASUREMENT SYSTEM FOR AN ANALYTE DETERMINATION AND A METHOD - A measurement system and method for operating a measurement system is disclosed for an analyte determination. The system includes an analysis unit, which is configured to determine a measured analyte value for a body fluid specimen that is applied, a fingerprint sensor, which is configured to detect fingerprint sensor signals for one or various users, and a control unit, which is connected to the analysis unit and the fingerprint sensor unit for data transmission. The control unit is configured to perform a user identification using the detected fingerprint sensor signals and after successful user identification to enable a determination of a measured analyte value with the analysis unit for an identified user. The control unit is additionally configured to analyze the detected fingerprint sensor signals and optionally additional detected fingerprint sensor signals in addition to the user identification in order to provide control signals for performing additional measurement system functions. | 11-03-2011 |
20110275912 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 11-10-2011 |
20110288386 | On-Body Medical Device Securement - Devices and methods for maintaining a medical device on-body are provided. Embodiments include medical device securement systems having first and second on-body securement elements. Also provided are systems and kits for use maintaining a medical device on-body. | 11-24-2011 |
20110295088 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 12-01-2011 |
20110295089 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 12-01-2011 |
20110295090 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 12-01-2011 |
20110295091 | METHOD AND SYSTEM FOR MANAGING PATIENT DATA - The present invention relates to a method and apparatus for managing patient data. In one aspect, the invention relates to a system for managing patient data having many instruments. The instruments have a sampling member for sampling a body fluid from a patient and are in direct communication with at least one other instrument. | 12-01-2011 |
20110301442 | DIAGNOSTIC ANALYTE COLLECTION DEVICE BASED ON FLEXIBLE POLYMERS WITH BIOLOGICAL SURFACE MODIFICATION AND MICROFLUIDIC FUNCTIONALITY - The invention relates to a device for detecting analytes. In order to supply a need in alternative prenatal diagnostic methods which do not include the risks known in the state of art, the present invention provides a device for detecting analytes, including a polymer fiber and capturing molecules, wherein the capturing molecules bind to an analyte and/or a linker molecule. | 12-08-2011 |
20110306852 | Pharmaceutical Dosages Delivery System - Pharmaceutical delivery systems for delivering dosages according to the present invention include a carrier component and a cap configured to seal an internal volume of the carrier component, wherein the cap includes a device that produces a unique current signature. Dosages prepared to be delivered according to embodiments of the invention find use in a variety of different applications, including clinical trials. | 12-15-2011 |
20110306853 | Body fluid sampling/fluid delivery device - A body fluid sampling or fluid delivery system includes a polymeric support and an array of polymeric microneedles coupled to the support, each of a microneedle having a height of 500 to 2000 μm and a tapering angle of 60 to 90°. A plurality of polymeric microchannels are provided with being associated with a microneedle. The plurality of polymeric microchannels are integrally formed with the array of polymeric microneedles without bonding. At least one polymeric reservoir is coupled to the plurality of microchannels. | 12-15-2011 |
20110319728 | BLOOD PARAMETER SENSOR AND FLOW CONTROL SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - A system is provided for sensing a blood parameter, such as an analyte, in a patient's vasculature. The system includes a vascular access device, a parameter sensor, a pressure sensor and a flow control device. The vascular access device supports the parameter sensor within the vasculature of the patient and includes an internal passageway for drawing samples onto and calibrating the parameter sensor. The pressure sensor is within the internal passageway. The flow control device modulates sample draw, calibration and flushing fluid flows to prevent or remove clots based on communication with the pressure sensor. Advantageously, the dynamic, adaptive modulation of flow reduces flushing and other cycle times while at the same time improving clot flushing. As another advantage, this enables reduction or elimination of the use of heparin and other anticoagulant components in the solution supplied for flushing and/or calibration. | 12-29-2011 |
20110319729 | MEDICAL DEVICE INSERTERS AND PROCESSES OF INSERTING AND USING MEDICAL DEVICES - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. | 12-29-2011 |
20120004521 | INTEGRATED LANCING TEST STRIP WITH RETRACTABLE LANCET - An integrated lancing test strip device includes a lancet configured to form an incision in tissue and a test strip coupled to the lancet for analyzing body fluid. A retention mechanism acts as a detent to hold the lancet in a static position relative to the test strip before forming the incision. The retention mechanism is configured to release the lancet for retracting the lancet relative to the test strip to reduce smearing of body fluid by the lancet during collection of the fluid with the test strip. In one form, the retention mechanism includes breakable tabs that are broken to release the lancet, and the lancet is retracted via translational movement. The retention mechanism in another form includes one or more dimples that release the lancet when the lancet is retracted via rotational motion. In a further form, the entire integrated device is rotated to collect fluid. | 01-05-2012 |
20120010481 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 01-12-2012 |
20120010482 | INSERTION SYSTEM - An insertion system for inserting a sensor into fatty tissue, comprising an insertion device and an insertion needle containing a sensor, wherein the insertion device comprises a holder for the insertion needle, and a piercing mechanism so as to move the holder, with the needle held by the same, in a feed direction for a puncture. The piercing mechanism changes the feed direction during the puncture so that, at the end of the puncture, an insertion needle held by the holder is oriented obliquely or perpendicular to the initial feed direction. Also provided are methods for controlling a needle moved by an insertion device. | 01-12-2012 |
20120016212 | Implantable Sensor Device - An implantable sensor device for capturing at least one physical, chemical, biological or physiological parameter in the body of a living being wearing the sensor device upon contact with the body fluid or tissue of the same, including a sensor housing, a sensor element that is accommodated in the sensor housing and has a capturing section, which has direct contact with the body fluid or the body tissue, or which internally adjoins a surface or opening section of the sensor housing that has contact with the body fluid or the body tissue, and a mechanically acting sensor cleaning device for cleaning the capturing section of the sensor element and/or the surface or opening section of the sensor housing adjoining the same. | 01-19-2012 |
20120016213 | BLOOD TEST STRIP AND AN INTRAVENOUS CATHETER SYSTEM - A blood test strip useful for venting a closed intravenous system and collecting a blood sample is described herein. The blood test strip includes a blood test strip, one or more vents, and a gripping member coupled to the proximal end of the blood test strip. The one or more vents are disposed between the distal and the proximal portions of the blood test strip. | 01-19-2012 |
20120022344 | INSERTION SYSTEM AND INSERTION DEVICE - An insertion system having a base unit for placing on the body of a patient and an insertion device that can be coupled to the base unit, wherein the insertion device comprises an insertion needle holder for holding an insertion needle and a drive mechanism for displacing the insertion needle holder in a pricking direction. According to the invention, the insertion device comprises a locking mechanism causing locking of the drive mechanism in an active state and being set to an inactive state in which the locking is released by coupling the insertion device to the base unit. | 01-26-2012 |
20120022345 | LANCET HAVING CAPILLARY CHANNEL AND STERILE PROTECTION ELEMENT AND METHOD FOR PRODUCING SUCH A LANCET - Lancets comprising a piercing element for puncturing the skin of a patient, a test region containing detection reagents for determining an analyte concentration of a body fluid sample, a capillary structure arranged in the piercing element for transporting a body fluid sample to the test region, and a sterile protection element, which encloses the tip of the piercing element. The capillary structure is blocked in a section surrounded by the sterile protection element. Also provided are methods for producing a lancet, comprising: producing a piercing element, which on the upper side has an upwardly open capillary structure; covering a section of the upper side of the piercing element and blocking the capillary channel in this section using a first material; covering a section of the underside using a second material; sterilizing the piercing element; and attaching a test region containing detection reagents to the piercing element. | 01-26-2012 |
20120022346 | Analyte Sensor Transmitter Unit Configuration for a Data Monitoring and Management System - Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided. | 01-26-2012 |
20120029324 | THERAPY PREDICTION AND OPTIMIZATION FOR RENAL FAILURE BLOOD THERAPY, ESPECIALLY HOME HEMODIALYSIS - A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient. | 02-02-2012 |
20120029325 | Device for determining the characteristics of peritoneal membrane - Device for determining the characteristics of peritoneal membrane comprising means for measuring glucose in the fluid drainage and a processing unit comprising means for determining the characteristics of the membrane as a function of that rate of glucose measured at different times. The invention also relates to a method for determining the characteristics of peritoneal membrane including the consideration of glucose measured at different moments in the liquid drainage. | 02-02-2012 |
20120035441 | MOUNT UNIT, SENSOR UNIT, MEASUREMENT APPARATUS AND SENSOR FIXATION METHOD - A mount unit | 02-09-2012 |
20120041285 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 02-16-2012 |
20120041286 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 02-16-2012 |
20120041287 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 02-16-2012 |
20120046529 | PHYSIOLOGICALLY ACTIVE SUBSTANCE COLLECTING DEVICE - A physiologically active substance collecting device, includes: a collecting section brought into contact with a body surface of a living organism to acquire a physiologically active substance from the body surface; and a liquid sending means for sending a solvent to the collecting section, the collecting section having an aperture at which the solvent flown by being sent from the liquid sending means contacts the body surface. | 02-23-2012 |
20120059231 | DEVICE FOR PERFORMING AT LEAST ONE MEDICAL FUNCTION - A device for performing at least one medical function on a user is proposed. The device has at least one medical functional element that is designed to perform the medical function. The medical function is selected from a diagnostic, a therapeutic and a surgical function. The device has at least one evaluation and control part that comprises at least one actuation component for controlling the medical function. The evaluation and control part has at least one casing and at least one battery receptacle. The battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery. The battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir. | 03-08-2012 |
20120065482 | DETERMINATION OF BLOOD PUMP SYSTEM PERFORMANCE AND SAMPLE DILUTION USING A PROPERTY OF FLUID BEING TRANSPORTED - The present invention provides methods and apparatuses related to measurement of analytes, including measurements of analytes in samples withdrawn from a patient. | 03-15-2012 |
20120071736 | Medical Device With a Fitting Having A Gas Venting Position - A blood parameter measurement cassette or other device is configured to control incidental liquid discharged during the device's calibration process. The cassette includes optical sensors which are chemically responsive to blood constituents and require calibration with a blood parameter monitoring device prior to use in a medical procedure. During the calibration process, an incidental amount of a liquid may be expelled from the cassette. The present invention is directed towards controlling the expelled liquid by absorbing it using an absorbent material disposed on the exterior of the cassette's main body. The absorbent material thereby prevents the liquid from causing detrimental effects to the monitoring and calibration equipment used in conjunction with the cassette. The scope includes additional embodiments wherein the inventive concept is applied to other fluid-handling medical devices that require venting of gases. | 03-22-2012 |
20120071737 | Breath Delivery System and Method - Some embodiments of the invention provide a mouthpiece for use with an electronic analyzer for breath analyte detection in an individual. The mouthpiece includes a biosensor and a hydration system. The biosensor includes a chemically active area where a chemical reaction takes place and the hydration system delivers a liquid to the chemically active area of the biosensor to at least one of enhance, enable, and facilitate the chemical reaction. The mouthpiece further includes hardware to transmit breath analyte data. | 03-22-2012 |
20120083677 | BLOOD ANALYZER - A blood analyzer capable of obtaining a blood analysis result instantaneously without sampling blood but rather applying a DC current to blood flowing through an artery and irradiating it with an ultrasonic wave is provided. It is equipped with a main measurement unit | 04-05-2012 |
20120088989 | Management Method And System For Implementation, Execution, Data Collection, and Data Analysis of A Structured Collection Procedure Which Runs On A Collection Device - In one embodiment, a method of performing a structured collection protocol by utilizing a collection device comprising a processor may include collecting at least one sample using the collection device. The at least one sample can be associated with biomarker data. A classification can be associated with the at least one sample via the processor. The classification can be based upon an intended use of the at least one sample. Compliance with an adherence criteria for the at least one sample can be determined via the processor. When the at least one sample is not compliant with the adherence criteria, an adherence event can be associated with the at least one sample, and the processor can perform at least one additional task that is based upon the classification associated with the at least one sample. | 04-12-2012 |
20120088990 | MEDICAL SENSOR SYSTEM - A medical sensor system ( | 04-12-2012 |
20120108921 | GASTRIC BANDING SYSTEM ADJUSTMENT BASED ON A SATIETY AGENT CONCENTRATION LEVEL - Methods and devices are provided for adjusting a gastric band to obtain a predetermined optimal expression of hormones. These hormones may be used to control appetite, metabolism and other weight control mechanisms. Ultimately, weight-loss efficacy is desired by tightening or loosening the gastric band based on hormone response. | 05-03-2012 |
20120108922 | Implantable Medical Sensor and Fixation System - An implantable medical device, such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation member that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation member may be configured to lie in a single plane when deployed or may be tubular in shape. The attachment of the housing and fixation member includes providing the fixation member with a linear attachment strut that is non-circular in cross section and providing the housing with external members that define an elongate channel, non-circular in cross section and receptive to the attachment strut. The attachment strut can be inserted transversely into the channel and the external member can be crimped over the strut to secure the housing and fixation member together. | 05-03-2012 |
20120116189 | BATTERY - A battery comprises a carrier foil, with solid state battery elements spaced along the foil and mounted on opposite sides of the foil in pairs, with the battery elements of a pair mounted at the same position along the foil. The carrier foil is folded to define a meander pattern with battery element pairs that are adjacent each other along the foil arranged back to back. | 05-10-2012 |
20120116190 | Continuous Analysis Device And Sample Component Control System - A continuous analysis apparatus capable of transmitting information about components in body fluid to another apparatus such as medicine dosing apparatus more correctly without giving a user displeasure. The continuous analysis apparatus according to the present invention includes a sensing unit | 05-10-2012 |
20120123227 | Apparatus, Systems, and Methods Adapted to Transmit Analyte Data Having Common Electronic Architecture - Embodiments provide apparatus, systems, and methods adapted to communicate analyte data and/or related information. In a first aspect, the apparatus includes a transmitter/receiver unit which is configurable as either a transmitter or a receiver. The transmitter/receiver unit may be coupled to an on-body sensor and may be configured as a transmitter, or may be coupled to a management unit and may be configured as a receiver as part of a continuous analyte monitoring system. Analyte data communication systems and methods are provided, as are other aspects. | 05-17-2012 |
20120123228 | METHODS AND APPARATUS FOR TESTING DISRUPTION OF A VAGAL NERVE - Method and apparatus for disrupting a gastric vagal nerve in the gastroesophageal region and testing the function and disruption of the vagal nerve. In one example embodiment, a treatment device applies ultrasound at a high energy level, such as high intensity focused ultrasound, to a vagal nerve to disrupt it and then ultrasound at a lower energy level to another portion of the vagal nerve, preferably further from the stomach, so as to stimulate the vagal nerve. Alternative ways to test the function or disruption of the vagal nerve involve using PCP-GABA, a pancreatic polypeptide, pressure changes inside the stomach, the gastric mucusol pH, a dye agent in the stomach, and other tests. | 05-17-2012 |
20120123229 | MODEL-BASED INFUSION SITE MONITOR - A medication delivery monitoring device is disclosed. The device includes a user interface configured to receive input information, and a sensor configured to measure a plurality of fluid state parameters of a fluid delivery channel through which the medication is delivered by a vascular access device (VAD) to an infusion site region of the patient. The device also includes a processor configured to determine a state of the infusion site region based on the plurality of measured fluid state parameters and the input information, and an output device configured to provide a communication regarding the state of the infusion site region. Methods and computer-readable mediums for monitoring medication delivery are also disclosed. | 05-17-2012 |
20120130207 | MICRO-NEEDLE DEVICE AND APPARATUS AND A METHOD FOR APPLYING A MICRO-NEEDLE ELEMENT TO A SITE ON THE SKIN OF A SUBJECT - A micro-needle device ( | 05-24-2012 |
20120143023 | SYSTEM AND METHOD FOR FACIAL NERVE MONITORING DURING FACIAL SURGERY - An apparatus for monitoring the activity of a surgeon. At least one wireless sensing unit is provided for monitoring potential damage to a nerve and is located at a first location of a body being operated on by a surgeon. The wireless sensing unit senses a change in the body at the first location resulting from potential damage to the nerve occurring at a second location of the body remote from the first location. The wireless sensing unit produces a wireless sensed change output signal indicative of the change in the body which is received by a receiver and generates a corresponding received output signal. An analyzer unit receives and analyzes the received output signal to determine the change in the body. An indicator responsive to the output of said analyzer unit indicates the change in the body to indicate the potential damage to the nerve the surgeon. | 06-07-2012 |
20120149999 | Tissue penetration device - A sampling module includes a module body portion with a lancet channel, a lancet slidably disposed within the lancet channel. A cover sheet is disposed over the lancet and a lancet channel that captures the lancet shaft in the lancet channel, and a sample reservoir for collection of a sample obtained by lancing a patient with the lancet. | 06-14-2012 |
20120150000 | Non-Invasive Monitoring Device - The invention concerns a device for non invasive monitoring of the concentration of a constituent of a human or animal bloodstream. In the preferred example the device comprises drive circuitry ( | 06-14-2012 |
20120157801 | Adaptor for On-Body Analyte Monitoring System - An analyte monitoring system comprising: an on-body housing; an analyte sensor coupled to the housing; an electrical output interface disposed on an outer surface of the housing; and a removable adaptor coupled to the housing. In one embodiment, a portion of the analyte sensor extends from the housing for implantation into a patient's body. The electrical output interface is electrically coupled to the analyte sensor. The removable adaptor is mechanically coupled to the housing and electrically coupled to the electrical output interface. The removable adaptor serves as a data conduit between the analyte sensor and a remote device. | 06-21-2012 |
20120190941 | Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. | 07-26-2012 |
20120190942 | Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. | 07-26-2012 |
20120190943 | Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. | 07-26-2012 |
20120203083 | Biologocal Test Kit - The biological test kit is a device for drawing and, optionally, testing biological samples. The biological test kit is an array of Lancets set in wells in a rigid base. Each lancet well is covered by a protective cover which when deformed permits the lancet to puncture a user or other patient. In one embodiment the biological test kit employs distinct covers for each lancet and in another the covers are formed from sheet material formed into blisters which cover the lancet. | 08-09-2012 |
20120203084 | POSITIONING SYSTEM, APPARATUS, AND METHOD FOR WIRELESS MONITORING OF ESOPHAGEAL pH VALUE - A positioning system, an apparatus, and a method for wireless monitoring of esophageal pH value. The positioning system includes an internal transmitting apparatus and an external recording apparatus. The external recording apparatus includes a second element, and the second element of the external recording apparatus cooperates with a first element of the internal transmitting apparatus. If the external recording apparatus detects that the internal transmitting apparatus is not located in the preset region, alerting action is conducted under the control of a micro-processor. The external recording apparatus periodically detects the intensity of a signal received by a second wireless transceiver module, under the control of the micro-processor, and if the signal intensity is not within the preset range, the alerting action is conducted under the control of the micro-processor. | 08-09-2012 |
20120209090 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 08-16-2012 |
20120209091 | Apparatus and Method for Processing a Set of Data Values - An apparatus for processing a set of data values, a data value representing a physiological measure of a body fluid at a time instant, comprising: an estimated probability function calculator for calculating an estimated probability function associated with the set of data values; a transform calculator for calculating a non-linear transform rule using a predetermined target probability function being different from the estimated probability function, so that the probability function of a set of transform data values is closer to the target probability function than the estimated probability function; and a transformer for applying the transform rule to the set of data values or to at least one further data value not included in the set of data values and sampled at the different time instant from the time instants for the set of data values to obtain at least one transformed value representing the physiological measure. | 08-16-2012 |
20120226115 | STACK MAGAZINE SYSTEM - A meter system for analyzing body fluids includes a supply magazine for storing a stack of test elements, a meter for analyzing fluid samples, and a transport system for transporting test elements from the supply magazine to the meter. The test element in one embodiment includes a lancet integrated test element that has a lancet coupled to a test strip. The transport system is configured to minimize damage to the test element. In one form, the transport system includes a shuttle that slides the top-most test element from the stack onto a connection portion of the meter. In another form, the transport system includes a drum that rotates to transport test elements from the supply magazine to a testing position and, once used, to a waste magazine for disposal. In a further form, the transport system includes a disc that rotates to transport the test elements. | 09-06-2012 |
20120238836 | System, devices, and methods for real-time monitoring of cerebrospinal fluid for markers of progressive conditions - Systems, devices, methods, and compositions are described for providing real-time monitoring of cerebrospinal fluid for markers of progressive conditions. | 09-20-2012 |
20120245438 | MEDICAL SYSTEM HAVING PLUG AND PLAY FUNCTION - A medical system is disclosed, which can be useable in particular for monitoring and/or controlling at least one bodily function of a user. The medical system comprises a control device and at least one medical user element embodied separately from the control device. The medical user element and the control device are designed to exchange data wirelessly. The medical system is designed to enable an automatic assignment step, wherein an exchange of personal data between the medical user element and the control device is enabled by the automatic assignment step. The medical system is furthermore designed to automatically initiate the automatic assignment step by means of an assignment coupling between the medical user element and the control device. The medical system is furthermore designed to enable a separation of the assignment coupling for medical operation of the medical system after the assignment step. | 09-27-2012 |
20120253144 | SENSOR - An embeddable sensor includes a sensor body, a detector housed in the sensor body, and a retaining mechanism mounted on a side surface of the sensor body. The retaining mechanism includes at least one projection on the side surface of the sensor body. The projection is of a V shape which is progressively wider and higher from a distal end toward a proximal end of the sensor body. The projection is made of a material whose hardness is lowered upon elapse of a certain period of time within a living body. When the embeddable sensor is inserted in the living body, the projection retains the embeddable sensor within the living body. Upon elapse of the certain period of time within the living body, the projection loses its capability to retain the embeddable sensor within the living body. | 10-04-2012 |
20120253145 | Systems and Methods for Transcutaneously Implanting Medical Devices - Systems and methods for transcutaneously implanting medical devices, such as in vivo analyte sensors, are provided. The systems and methods involve the use of introducers or inserters made of shape memory alloy (SMA) materials which are transitionable from one operative state or configuration to another operative state or configuration, wherein the transition from state to state enables the transcutaneous implantation and/or transcutaneous explantation of the medical device. | 10-04-2012 |
20120259185 | Systems, Methods and Devices for Adjusting the Insertion Depth of a Cannula Associated with a Portable Therapeutic Device - Systems, methods and devices are described herein for adjusting the insertion depth of a cannula associated with a portable therapeutic device within the body of a patient. The systems may include a mounting unit securable to the skin of the patient and having a mounting base and a well defining a passageway through the mounting base and a cannula unit including a cannula subcutaneously insertable through the well of the mounting unit. The well may have an adjustable height and/or adjustable anchoring mechanisms that allow for varying and customized insertion depths of the cannula within the body of the patient. | 10-11-2012 |
20120259186 | Method and apparatus for an improved sample capture device - A body fluid sampling device is provided. A mesh ( | 10-11-2012 |
20120265033 | EVALUATING DOSING FROM AN IMPLANTABLE INFUSION DEVICE - A method for evaluating dosing from an implanted infusion system that includes receiving input regarding the identity of a therapeutic agent into an external device. The method further includes displaying on the external device a predetermined set of symptoms associated with the therapeutic agent; receiving input into the external device regarding with which of the symptoms the patient presents; and determining whether the therapeutic agent is being delivered, or has been delivered, at an appropriate dose based on the input identity of the therapeutic agent and the input symptoms. | 10-18-2012 |
20120265034 | TISSUE-INTEGRATING SENSORS - Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided. | 10-18-2012 |
20120265035 | ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors. | 10-18-2012 |
20120265036 | ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors. | 10-18-2012 |
20120265037 | ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors. | 10-18-2012 |
20120271123 | Integrated lancing device - A lancing device is provided that has a housing with a length greater than a width. Electronics are positioned in an interior of the housing. A test strip aperture is in the housing and is adapted to receive a body fluid test strip. A lancet aperture is positioned in line with the test strip aperture. | 10-25-2012 |
20120271124 | Thrombospondin Fragments and Uses Thereof In Clinical Assays for Cancer and Generation of Antibodies and Other Binding Agents - The invention relates to thrombospondin fragments found in plasma, their use or use of portions thereof in diagnostic methods, as method calibrators, method indicators, and as immunogens, and as analytes for methods with substantial clinical utility; and their detection in plasma or other bodily fluids for purpose of diagnostic methods, especially for cancer. | 10-25-2012 |
20120271125 | DEVICES AND METHODS FOR DELIVERY AND/OR WITHDRAWAL OF FLUIDS AND PRESERVATION OF WITHDRAWN FLUIDS - The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. | 10-25-2012 |
20120271126 | Apparatus for obtaining and analyzing a blood sample with a lancet coupling mechanism - An apparatus for obtaining and analyzing a blood sample is presented. The apparatus comprises an integrated drive unit having a common drive source and a drive force transmission gearing that couples a lancet drive, a device for advancing a magazine, and a sample transfer device to the drive source. A tensioning rotor and a drive rotor are mounted so that they are rotatable coaxially to one another. A first cam control converts the rotation of the drive rotor into a radial forward and reverse movement of a drive rod. A second cam control converts the rotational movement of the tensioning rotor into a linear movement of a link slide. A switching link moved by the link slide rotates the magazine an additional step. A third cam control converts the rotational movement of the tensioning rotor into a linear movement of a pressure tappet perpendicular to the piercing axis. | 10-25-2012 |
20120271127 | SANITARY SWAB COLLECTION SYSTEM, MICROFLUIDIC ASSAY DEVICE, AND METHODS FOR DIAGNOSTIC ASSAYS - Biohazard specimen collection containers are provided with an external disposable skin, that is stripped away and discarded after the biohazardous specimen is collected, thus reducing or eliminating objectionable or dangerous residues on the outside surfaces of the container. Further, we teach that the sample collection container with external disposable skin may also serve as an integrated microfluidic biosample processing and analytical device, thereby providing a single entry, disposable assay unit, kit and system for “world-to-result” clinical diagnostic testing. These integrated assay devices are provided with synergic, multiple safe-handling features for protecting healthcare workers who handle them. The modified collection containers and analytical devices find application, for example, in PCR detection of infectious organisms or pathogenic markers collected on a swab. | 10-25-2012 |
20120277551 | INTERSESSION MONITORING FOR BLOOD FLUID REMOVAL THERAPY - Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patent parameters. By comparing the patient's current parameters to past parameters in response to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session. | 11-01-2012 |
20120277552 | CHRONIC pH OR ELECTROLYTE MONITORING - Methods include monitoring blood pH or electrolyte levels and setting initial fluid parameters, such as dialysate fluid parameters or replacement fluid parameters, for a blood fluid removal session based the monitored data. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session. | 11-01-2012 |
20120283528 | TAPE MAGAZINE WITH REWIND LOCK AND INTEGRATED TAPE RELEASE - A replaceable magazine for use in an analytic test instrument a plurality of analytic aids on a carrier tape. The analytic aids can be made available in an application position of the magazine by means of the carrier tape. The magazine has a supply reel for holding regions of the carrier tape with unused analytic aids and a take-up reel for holding regions of the carrier tape with used-up analytic aids. The carrier tape can be moved in a spooling direction from the supply reel to the take-up reel. The magazine has a rewind lock of the take-up reel. The magazine has a tape release device, which is configured to make available a take-up reel tape reserve of the carrier tape on the side of the application position facing the take-up reel. The take-up reel tape reserve enables a lifting movement of an analytic aid situated in the application position. | 11-08-2012 |
20120289795 | Self-Flowing Measuring System - The invention relates to a method and arrangement for continuously measuring substances in a pressurised body fluid. A probe ( | 11-15-2012 |
20120302844 | SKIN MOUNTED MEDICAL PATCH DEVICE - Medical patch device mountable on skin for drug delivery or analyte sensing, including a mounting base ( | 11-29-2012 |
20120316408 | INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BY-PRODUCTS FROM MICROORGANISMS - pH indicator compositions, solutions and suspensions and pH indicating food storage devices, medical devices and components thereof are provided for visually monitoring, detecting, and/or determining the presence of metabolic by-products from harmful or potentially harmful microorganisms. Also provided are methods of use and preparation of the pH indicator compositions, solutions and suspensions. | 12-13-2012 |
20120316409 | Hygiene Materials and Absorbents - A topical product including but not limited to a feminine hygiene product or incontinence shield which contains at least two kinds of particulate metals distributed throughout which, when in contact with moisture, form a galvanic current (virtually if not completely imperceptible to the user) that has antimicrobial effect on all pathogens. Galvanic current virtually or completely imperceptible to the user facilitates antimicrobial effect. | 12-13-2012 |
20120323091 | METHODS AND APPARATUS FOR GUIDING MEDICAL CARE BASED ON DETECTED GASTRIC FUNCTION - Embodiments relate to guiding medical care based on detected gastric function. For example, gastric acid stimulant or suppressant is administered, and then a change in the gastric juice H+ concentration is measured. This change is compared to a guidance H+ concentration differential indicative of relatively healthy gastric function. Medical care is guided based on a relatively healthy gastric function if the measured H+ concentration differential is equal to or exceeds the guidance H+ concentration differential, while medical care is guided based on a relatively unhealthy gastric function if the measured H+ concentration differential is less than the guidance H+ concentration differential. Disclosed embodiments implementing this procedure include, but are not limited to, methods, apparatus, processors, computer programs, and computer-readable mediums. | 12-20-2012 |
20120330115 | ANALYTE MONITORING SYSTEMS AND METHODS - A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band. | 12-27-2012 |
20130006066 | Systems and Methods for Alcohol Consumption Monitoring - Various embodiments of the present inventions are related to monitoring physical characteristics of a monitored individual including, but not limited to, alcohol consumption by the monitored individual. | 01-03-2013 |
20130006067 | METHOD AND DEVICE FOR DETERMINING A RISK OF GRAFT REJECTION - The invention relates to a method for determining a risk of permanent rejection of a graft after being transplanted to a recipient, said method being characterized in that it includes the following steps: (a) entering physiological/clinical characteristics of the recipient and the donor into a computation unit by means of an input interface, said characteristics including the gender of the recipient, the creatinine level of the graft donor when sampled, the age of the recipient at the time of the transplant,—the number of renal transplants previously received by the recipient,—a creatinine level of the recipient measured twice at at least one predetermined point in time after the transplant, a proteinuria level of the recipient measured at a predetermined point in time after the transplant, and the existence of an episode of permanent rejection of the transplant during the first year of the transplant; (b) determining the parameters on the basis of said characteristics; (c) combining said parameters so as to obtain a risk score of permanent rejection of the gait; and (d) analyzing said risk score so as to determine a risk of permanent rejection of a graft. | 01-03-2013 |
20130030263 | Device for Taking a Sample of a Body Fluid and Method for Implementing Same - The invention relates to a device ( | 01-31-2013 |
20130035564 | REAL TIME INTRAVASCULAR MONITORING DEVICE - A real time tissue sampling and analysis system includes a catheter including an elongated body defining at least one internal lumen, a sampling device positionable within the at least one internal lumen of the catheter for collecting a tissue sample, and a biochip disposed within the at least one internal lumen. The biochip includes a substrate for receiving the tissue sample, a marker for interacting with the tissue sample, and a sensor for identifying a characteristic of the tissue sample and transmitting data about the tissue sample to a processing unit for analysis. | 02-07-2013 |
20130035565 | Method and System for the Reactivation of an Implantable Chemical Sensor - A method for the operation and, in particular, for the reactivation of an implantable chemical sensor that measures values in bodily fluid, including the steps of wetting the sensor surface with a reactivation substance that carries out a chemical reaction on the sensor surface that removes molecules originating in the bodily fluid, or the reaction or degradation products thereof, which have collected on the sensor; and dewetting the sensor surface of the reactivation substance, wherein the sensor surface is wetted and dewetted with the reactivation substance in situ. | 02-07-2013 |
20130035566 | Method and Apparatus for Enhancement of Transdermal Transport - According to the present invention, a method for enhancing transdermal transport is disclosed. The method includes the steps of increasing a permeability an area of a membrane with a permeabilizing device. The membrane may be, inter alia, biologic skin or synthetic skin. The permeabilizing device may be an ultrasound-producing device. A substance is transported into and through the area the membrane. The substance may be a drug, a vaccine, or a component of interstitial fluid. | 02-07-2013 |
20130041236 | SAMPLE ANALYSIS SYSTEM AND METHOD OF USE - A sample collection device having a sample container and microfluidic device having one or more microfluidic circuits, the system for analyzing biological samples. The microfluidic device has a sample inlet port, a microconduit in communication with the inlet port and with reaction chamber. The reaction chamber is connected to an air vent via another microconduit. Air may be vented from the microfluidic circuit via the air vent of the microfluidic circuit via an air vent in the sample container. | 02-14-2013 |
20130053658 | MR SPECTROSCOPY SYSTEM AND METHOD FOR DIAGNOSING PAINFUL AND NON-PAINFUL INTERVERTEBRAL DISCS - An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine. | 02-28-2013 |
20130053659 | Electric Functional Adhesive Bandage - An electronic functional adhesive bandage includes an adhesive layer and a cover layer, between which an electric energy source, an electric connection element, and an electronic control device are arranged. The electronic functional adhesive bandage also includes a switching element configured to control the power consumption of the electronic control device and to establish an electric connection between the electronic control device, the electric connection element, and the electric energy source. | 02-28-2013 |
20130053660 | Blood Component Detection Device - The present invention relates to a blood component detection unit, which comprises: a capsule body having a first surface; a needle array including a plurality of needles, each of the needles have an opening and an inner hollow space, and each of the needles protrudes out of the first surface; a detection chamber disposed inside the capsule body and connected with the inner hollow space; a sensing chip disposed inside the capsule body; and a plurality of sensing elements disposed on the sensing chip. | 02-28-2013 |
20130066171 | Lancet Magazine and Method for the Production Thereof - A lancet magazine is disclosed which includes a housing and a plurality of lancets each of which is enclosed in a sterile chamber of the housing, wherein the chambers each have a puncturing opening which is closed with a foil, wherein the lancets include a sample receiving device for receiving body fluid and the chambers each include a further opening which is closed with a membrane that is permeable to gas and fluid and includes a lower side that faces the lancet and serves to receive body fluid from the sample receiving device and an upper side that serves to transfer body fluid to a test field arranged on the membrane. | 03-14-2013 |
20130079603 | INTRAGASTRIC IMPLANT DEVICES - An intragastric anchor implant device with an elongate member having proximal and distal ends with atraumatic features disposed thereon is described herein. The atraumatic features inhibit damage to the tissues of the stomach and the gastrointestinal tract and help anchor the device. The elongate member may be substantially rigid to resist bending and engage a tissue of the stomach or gastrointestinal tract to prevent passage therethrough and may include one or more bends to conform to the shape of the tract. The anchor implant device may be coupled with a therapeutic device, such as an intestinal bypass sleeve with a sliding seal, such as an expandable structure, that secures the sleeve to direct a flow of food particles from the stomach therethrough, for use in treating various disorders, including obesity and diabetes. Methods of deploying the anchor implant devices are also disclosed. | 03-28-2013 |
20130079604 | SYSTEMS AND METHODS FOR PARENTERALLY PROCURING BODILY-FLUID SAMPLES WITH REDUCED CONTAMINATION - The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media. | 03-28-2013 |
20130090535 | SYSTEMS, DEVICES, AND METHODS INCLUDING PARAMAGNETIC OSCILLATION, ROTATION, AND TRANSLATION OF HEMOZOIN ASYMMETRIC NANOPARTICLES IN RESPONSE TO DARK-FIELD OR RHEINBERG DETECTION OF THE PRESENCE OF HEMOZOIN - Systems, devices, and methods are described for providing a monitor/treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection. | 04-11-2013 |
20130096399 | METHODS AND DEVICES FOR DETECTING BOWEL PERFORATION - The present disclosure relates to methods and devices to detect perforation of the bowel, for example, resulting from surgical procedures, such as laparoscopy, diagnostic procedures, such as colonoscopy, medical conditions, such as diverticulitis, and trauma. The present disclosure also relates to filtration systems and electrical connector assemblies for use in the methods and devices. | 04-18-2013 |
20130102860 | Drains for Use in Medical Applications and Methods of Using the Same - A drain for use in medical applications may include an elongated conduit configured to be implanted in a body cavity, wherein the conduit has a proximal end and a distal end. The conduit may include at least one channel configured to drain fluid from the body cavity and at least one lumen extending from the proximal end to the distal end of the conduit. The lumen may be at least partially surrounded by the at least one channel and may be separated from the at least one channel by a wall. At least one hole in the wall may be configured to provide fluid communication between the lumen and the at least one channel. | 04-25-2013 |
20130116516 | PATCH FOR TREATING AND ALLEVIATING SYMPTOMS OF SKIN DISEASES ACCOMPANIED BY EFFUSION OF BLOOD PROTEINS - Provided is a patch for treating skin diseases or alleviating symptoms of the skin diseases involving an exudation of blood proteins, or for absorbing blood proteins exuded to the skin. | 05-09-2013 |
20130123589 | WEARABLE DEVICE, BIOLOGICAL GAS MEASUREMENT DEVICE AND METHOD - One aspect of the present invention relates to a wearable device worn in contact with a user's skin including a gas reservoir structure configured to, when the user wears the wearable device, form a space for accumulating a biological gas component released from a skin surface or expiration of the user and a gas sensor device configured to measure the biological gas component accumulated in the formed space. | 05-16-2013 |
20130131467 | METHOD AND DEVICE FOR PUNCTURE OF INSERTION NEEDLE INTO SUBCUTANEOUS FATTY TISSUE - An insertion device with an underside for placing on the skin of a patient, which has a recess for an insertion needle. The insertion device has means for forming a skin surface rising like a step or slope and facing towards the recess, preferably bearing on the recess. The means for forming the step or slope may include first and second pressure areas for pressing the skin with the recess for the needle located between the first and second pressure areas. The device may be configured whereby a downwardly extending cutting plane, in which the insertion needle lies, intersects the first pressure area in a first line and the second pressure area in a second line, and wherein the first line in the vicinity of the recess extends at a greater height than the second line. At least one of the two pressure areas may be a strip. | 05-23-2013 |
20130131468 | MEDICAL DEVICE COMPRISING A MULTIPART HOUSING - A medical device for carrying out at least one medical function, comprising at least one element that can be at least partially inserted into a body tissue of a user and further comprising at least one housing that can be placed on a skin surface of the user. The housing has a multipart design and comprises at least one functional component. The functional component can be connected to the insertable element. The housing further comprises at least one protective component. The protective component is designed to at least partially enclose the functional component. The protective component can be connected to the functional component, particularly after insertion of the insertable element. | 05-23-2013 |
20130144133 | DEVICES WITH SELECTIVELY PERMEABLE BARRIERS - Devices having selectively permeable barriers are provided with a substrate, a first layer overlaying at least a portion of the substrate, and a second layer overlaying at least a portion of the first layer. The first layer has at least one first pore and the second layer has at least one second pore. At least a portion of the first and/or second layers are movable with respect to each other between an open condition and a closed condition in response to a change in an environmental factor. In the open condition, the first and second pores are substantially aligned to allow fluid communication between the substrate and the outside environment. In the closed condition, the first and second pores are substantially misaligned to prevent fluid communication between the substrate and the outside environment. | 06-06-2013 |
20130144134 | NMR SYSTEMS FOR IN VIVO DETECTION OF ANALYTES - This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response. | 06-06-2013 |
20130144135 | METHOD AND APPARATUS FOR THREE DIMENSIONAL RECONSTRUCTION OF A JOINT USING ULTRASOUND - A method of generating a 3-D patient-specific musculoskeletal model. The method includes acquiring a plurality of raw radiofrequency (“RF”) signals from an A-mode ultrasound scan of the bone while tracking the acquiring in 3D space. The bone contours are isolated in each of the plurality of RF signals and transformed into a point cloud. A 3-D model of the bone is then optimized with respect to the point cloud. The 3-D patient-specific musculoskeletal model may include a model of a bone, a model of a joint, a model of cartilage, or a combination thereof. | 06-06-2013 |
20130172695 | Medical Skin Mountable Device and System - A medical device is provided comprising a transcutaneous device unit and a process unit. The transcutaneous device unit may comprise a transcutaneous device for transporting a fluid through a skin portion of a subject, and a mounting surface adapted for application to the skin of the subject. The process unit may comprise a reservoir adapted to contain a fluid drug, the reservoir comprising an outlet means allowing the transcutaneous device to be arranged in fluid communication with an interior of the reservoir, and an expelling assembly for expelling a fluid drug out of the reservoir and through the skin of the subject via the transcutaneous device. The transcutaneous device unit and the process unit further comprise coupling means allowing the reservoir unit to be secured to the transcutaneous device unit in the situation of use. By this arrangement a two-unit system is provided which can be used in a convenient and cost-effective manner. | 07-04-2013 |
20130172696 | MEDICAL HAND-HELD MEASURING DEVICE WITH EXCHANGEABLE PROBE - The invention relates to a medical hand-held measuring device for measuring the pH value and/or the temperature of wounds, including a housing ( | 07-04-2013 |
20130178722 | Sharp Tip Carbon Nanotube Microneedle Devices and Their Fabrication - Carbon nanotube needles and needle arrays are described in which the precursor pillars are etched by oxygen plasma treatment to provide tapered and/or sharp-tip needles. Processes, products by process, and devices incorporating the sharp-tip needles are further described. | 07-11-2013 |
20130184541 | INFUSION SET COMPONENT WITH MODULAR FLUID CHANNEL ELEMENT - An infusion set component of a fluid infusion device and/or a fluid infusion port component for delivery of fluid to a patient is compatible with a cooperating fluid channel module. The fluid channel module includes a body section having coupling features to mate with a base of the component. The fluid channel module also includes an interior fluid flow channel formed within the body section to receive fluid from the fluid infusion device and/or from a syringe or pen delivery device. The fluid channel module also includes a conduit having a first end in fluid communication with the interior fluid flow channel, and having a second end to deliver the fluid to the patient. | 07-18-2013 |
20130184542 | Method and System for Providing an Integrated Analyte Sensor Insertion Device and Data Processing Unit - Method and apparatus for providing an integrated analyte sensor and data processing unit assembly is provided. | 07-18-2013 |
20130184543 | Systems and Methods for Obtaining Analytes From a Body - A method may include collecting at least one analyte from within a body, ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and receiving the ejected at least one analyte outside the body. A system may include a means for collecting at least one analyte from within a body, a means for ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and a means for receiving the ejected at least one analyte outside the body. | 07-18-2013 |
20130190578 | Low pain penetrating member - Reducing the volume or drag on skin or sharpness of the penetrating member entering the wound during the cutting process will reduce the pain associated with lancing, and result in less power desired for retraction of the penetrating member from the skin. A variety of other penetrating member configuration as shown in the application. | 07-25-2013 |
20130197325 | ANTI-COAGULANT INFUSION FLUID SOURCE - Methods and systems for preventing or eliminating blood coagulation or thrombus during use of an intravenous anti-thrombotic sensor are disclosed. The method further comprises for providing antimicrobial into the infusion fluid source. An anti-thrombotic sensor is also disclosed that comprises a coating of a complex of a non-heparin anti-thrombotic agent and an alkylbenzyldimethyl ammonium cationic salt. | 08-01-2013 |
20130211211 | SAMPLING APPARATUS - There is provided a chip-type sampling apparatus to be attached so that a sampling side of the sampling apparatus faces the skin, the apparatus including a porous adsorption layer that faces the sampling side and has a pore diameter in a range of 0.1 to 1000 nm. One example of the adsorption layer includes at least three porous layers with different central pore diameters that are laminated from the sampling side in descending order of the central pore diameters. The sampling apparatus should preferably also include a layer that sucks air through the adsorption layer. | 08-15-2013 |
20130225949 | METHOD FOR DETECTING BODY PARAMETERS - A biometric sensor includes a prosthesis for at least one joint having one or more biometric transceivers. The one or more biometric transceivers are capable of transmitting at least one energy wave into a procedure area, quantitatively assessing a behavior of the at least one energy wave, and assessing particulate matter using the at least one energy wave. | 08-29-2013 |
20130225950 | ANXIETY MONITORING - A patient monitoring system comprises a probe module ( | 08-29-2013 |
20130237780 | Biomarker Sampling in the Context of Neuromodulation Devices, Systems, and Methods - Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices, systems, and methods. Some embodiments, for example, are directed to catheters, catheter systems, and methods for sampling biomarkers that change in response to neuromodulation. A system can include, for example, an elongated shaft and a neuromodulation and sampling assembly having a neuromodulation and a sampling element. | 09-12-2013 |
20130237781 | Transcutaneous Device - The present application relates to a transcutaneous device for use in delivery and/or sensor devices or the like. The transcutaneous device is of a type which can be used as a component in different types of delivery and/or sensor devices and which is applied after a base part has been applied to the patient's skin. The application relates to a transcutaneous device to be secured to a base part which base part during use is secured to a patient's skin, the transcutaneous device comprises a housing and a subcutaneous part secured unreleasably to the housing, said transcutaneous device is provided with attachment means attaching the transcutaneous device to the base part. The attachment means comprises more than one inwardly or outwardly protruding parts sequentially arranged in direction of insertion along an outer surface of the body of the transcutaneous device. The direction of insertion is coinciding with the direction in which the insertion needle points during insertion. | 09-12-2013 |
20130245401 | SYSTEMS AND METHODS FOR PROCESSING ANALYTE SENSOR DATA - Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously. | 09-19-2013 |
20130245402 | SENSOR HAVING FERROGEL WITH MAGNETIC PARTICLES - A sensor for detecting a condition includes a hydrogel configured to change thickness or volume in response to the condition. Magnetic particles are arranged in the hydrogel so that a magnetic property of the hydrogel changes with changes of thickness or volume of the hydrogel. Some such sensors include a magnetic-field detector that measures the magnetic field of the hydrogel. Other such sensors include a device coil is arranged with respect to the hydrogel so that changes in the magnetic property modulate an electrical property of the sensor. A sensing system using such a sensor includes a reader spaced apart from the sensor and including a reader coil and a resonance detector coupled to the reader coil to detect a the resonant frequency of the sensor. Changes in the magnetic property detectably modulate the resonant frequency. | 09-19-2013 |
20130245403 | WIRELESS FLOW SENSOR - Devices and methods useful for non-invasively measuring and indicating a rate of fluid flow are disclosed. In one embodiment, a sensor housing adapted to received fluid flow therethrough is provided. A radio frequency tag and a masking element can be disposed in the sensor housing. The masking element and the radio frequency tag can be configured to move relative to one another. The relative positions or movement can alter the response of the radio frequency tag to a wireless signal (which can be emitted from an external reading device, for example) and thereby indicate a rate of fluid flowing through the housing. For example, in some embodiments, the masking element can selectively cover at least part of the radio frequency tag in correspondence to the flow rate, which can change a characteristic of the radio frequency tag's response to the wireless signal. | 09-19-2013 |
20130245404 | WIRELESS FLOW SENSOR METHODS - Devices and methods useful for non-invasively measuring and indicating a rate of fluid flow are disclosed. In one embodiment, a sensor housing adapted to received fluid flow therethrough is provided. A radio frequency tag and a masking element can be disposed in the sensor housing. The masking element and the radio frequency tag can be configured to move relative to one another. The relative positions or movement can alter the response of the radio frequency tag to a wireless signal (which can be emitted from an external reading device, for example) and thereby indicate a rate of fluid flowing through the housing. For example, in some embodiments, the masking element can selectively cover at least part of the radio frequency tag in correspondence to the flow rate, which can change a characteristic of the radio frequency tag's response to the wireless signal. | 09-19-2013 |
20130253287 | BIOSENSOR WITH FINGER-POSITIONING FUNCTION - The present invention provides a biosensor with finger-positioning function, comprising: a bottom plate, a cover, and a test-strip socket; wherein the cover mounted on the bottom plate has a front end provided with a guiding plate for positioning a finger, and the guiding plate has a center line and a guiding surface, in which the center line passes through a center of the guiding surface; and the test-strip socket is formed at the front end of the cover. When using the biosensor, the user can rest his/her wrist and palm on the cover of the biosensor and rest the punctured finger on the guiding surface provided at the front end of the cover to align the test strip with the blood drop on the finger so as to simplify the measurement. | 09-26-2013 |
20130253288 | GUIDE FOR PLACEMENT OF CATHETER INTO BRAIN AND A METHOD OF UTILIZING THE SAME - The subject matter discloses an apparatus for detecting an environment within a body comprising: an apparatus comprising a stylet and a catheter capable of being inserted into the body; a bio-sensing module for detecting a predefined material within the body, upon insertion of the stylet and catheter with close proximity to the predefined material | 09-26-2013 |
20130253289 | DIAGNOSTIC DEVICE - An improved diagnostic analyte monitoring device has partially retractable hollow guide needles for the intradermal placement of diagnostic elements fixedly connected to measuring means within this device obviating the need to remove the guide needle and to connect the diagnostic elements to measuring means after placement into the skin. A flexible surface adhering to the skin serves for the subcutaneous implantation of the diagnostic elements within the guide needles and partial retraction of the guide needles exposes the active surface to body fluid, actuated by means designed for easy handling and safe operation. Concentration-time profiles of endogenous and exogenous analytes measured with the device are used to improve drug treatment modalities on an individualized basis. | 09-26-2013 |
20130253290 | PARAMAGNETIC MATERIAL PATCH - A microneedle patch for assessing oxygenation at a localized region of interest includes microneedle projections which extend into a region of interest, a layer of material bonded to the microneedles which allows the patch to releasably engage the localized region of interest, and a paramagenetic material dispersed within the patch. An oxygen impermeable layer of material may be disposed over the oxygen permeable layer of material such that environmental oxygen is inhibited from interacting with the paramagnetic material. | 09-26-2013 |
20130261412 | SYSTEM AND METHOD FOR MANAGING FLUID LEVELS IN PATIENTS BASED UPON CREATININE CLEARANCE - A creatinine clearance monitoring and fluid level management system for use in the treatment of patients. The system establishes and adjusts the dosing of intravenous fluids based upon periodic creatinine clearance calculations based upon a system specified frequency. Warning or alert messages or signals are produced if creatinine clearance levels indicate the need for the administration of additional fluids based upon a creatinine clearance result below an established normal threshold. Furthermore, the system generates a warning to trigger a more serious intervention in the event a patient's creatinine clearance rate falls below a lower established threshold or the system determines that an inordinate amount of fluids have been administered without the anticipated response. The creatinine clearance monitoring and fluid level management system is particularly useful for patients in a hospital or in-patient environment, and particularly those post-operative patients or those in intensive care. | 10-03-2013 |
20130267797 | METHOD FOR ENHANCING THE PERFORMANCE AND GENERAL CONDITION OF A SUBJECT - The invention concerns the therapy with a cardiac resynchronization device (CRT) and/or therapy with an automated internal cardiac defibrillator (ICD) for treating patients with any cancer or patients with cachexia due to acute or chronic illness other than cardiac illness, including malignant tumor disease, COPD, chronic renal failure, liver cirrhosis, chronic infections, and/or AIDS. Areas of application are the life sciences, in particular medicine and medical technology. | 10-10-2013 |
20130274568 | FULLY INTEGRATED WEARABLE OR HANDHELD MONITOR - An arrangement comprises a housing containing one or more components configured for at least one of body fluid sampling and analysis. The arrangement includes a housing containing one or more components configured for at least one of body fluid sampling and analysis, and a body attachment element. The housing and the body attachment element are connected by a quick-release mechanism configured to facilitate removal of the housing from the body attachment element. | 10-17-2013 |
20130281802 | SENSOR SYSTEM, AND METHOD OF USING SENSOR SYSTEM - A sensor system and a sensor system using method improve operability of a placing operation of placing a sensor in a living body and improve user-friendliness of users. The sensor system has: a sensor member which has the sensor which detects analyte components of the living body and transmits a signal, and a retaining portion which retains the sensor; a needle assembly detachably attached to the sensor member and having a guide needle which guides insertion of the sensor to the living body; a signal processing circuit member detachably attached to the sensor member, and having an electronic circuit which processes the signal from the sensor; and a fixing member which fixes the sensor member to skin of the living body, and the sensor is placed in the living body in a state in which the signal processing circuit member is attached to the sensor member. | 10-24-2013 |
20130289369 | Methods and Apparatus for Renal Neuromodulation - A thermal neuromodulation apparatus, system, and methods for the ablative and non-ablative application of thermal energy to the renal nerves of a patient are disclosed. The thermal neuromodulation apparatus includes an elongated, hollow body configured to traverse the tortuous intravascular pathways of the renal vasculature and includes an expandable structure bearing electrodes and configured to selectively apply thermal energy via electric fields to the renal nerves through a vessel wall. The thermal neuromodulation apparatus may also include sensors and an imaging apparatus to obtain data from the treatment area before, during, and after neuromodulation to monitor and/or control the neuromodulation process. | 10-31-2013 |
20130296664 | Biosensor and Method for Providing a Biosensor - A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate ( | 11-07-2013 |
20130310665 | METHOD - The present invention relates to a method for fabricating a microneedle which comprises the steps of spraying a composition into a mould, drying the composition and removal of the dried composition from the mould, thereby forming a microneedle that, when applied to the skin of a subject, pierces the stratum corneum to access the underlying tissue of the subject. The present invention also relates to a method for coating a microneedle which comprises the steps of spraying a composition onto a microneedle and drying the composition at an ambient temperature, thereby forming a coated microneedle that, when applied to the skin of a subject, pierces the stratum corneum to deliver the sprayed material to the underlying tissue of the subject. | 11-21-2013 |
20130317322 | METHOD FOR EVALUATING AND MODIFYING THE STATE OF HYDRATION OF A SUBJECT - This invention provides methods and devices for individual evaluating and modifying the state of interstitial hydration of an individual. | 11-28-2013 |
20130317323 | DECOMPRESSION MECHANISM, PUNCTURING APPARATUS, AND BLOOD ANALYSIS APPARATUS - Provided are a decompression mechanism capable of performing a desired pressure reduction by simple operation and having improved operability, a puncture device, a blood analysis device, and a sensor mounting mechanism. A needle puncturing device includes: a piston having at one end thereof an end part for forming a part of a sensor mounting mechanism and at the other end an end part for slidably supporting a rod of a lancet section; a cylinder for slidably containing therein the end section of the piston; and packing mounted to the inner periphery of the end part of the piston and maintaining the air-tightness of the outer periphery of the rod. When the piston is moved in the direction toward the cylinder with a skin contact part in contact with the skin, the volumes of an internal space and a pressure reduction chamber are increased to produce a reduced pressure. | 11-28-2013 |
20130317324 | DEVICES AND METHODS FOR POWERING A MEDICAL DEVICE - Devices and methods for powering a medical device for sustained delivery of fluids or continuous monitoring of body analyte. The devices may comprise a pumping mechanism, a driving mechanism for activating the pumping mechanism to dispense fluid, and a power source coupled to the driving mechanism and having an energy storage cell for providing a pulsed power to the driving mechanism. The methods may be implemented by activating the driving mechanism using pulsed energy in the form of at least one pulse train pattern accumulated in and discharged from an energy storage component. | 11-28-2013 |
20130324807 | SPACE-SAVING MAGAZINING OF ANALYTICAL AIDS - An analytical magazine is proposed, which comprises a plurality of analytical aids accommodated in chambers. The analytical magazine is arranged to be accommodated in at least two orientations in an analytical system. The analytical magazine is furthermore arranged to provide the analytical system, in the orientations, in each case with a plurality of analytical aids. At least one sampling movement can be executed by means of the analytical aids. The analytical magazine is arranged to make a remagazining of the analytical aids possible. | 12-05-2013 |
20130331666 | MENSTRUAL FLUID ANALYSIS - A disposable menstrual fluid fractionation apparatus for use in situ during menstruation is disclosed. The apparatus may include a filter configured to remove a particulate component of menstrual fluid from a liquid component of the menstrual fluid. A receptacle may be coupled to the filter. The filter, receptacle, and an analyte sensor may be integrated into a disposable feminine hygiene product. The integrated analyte sensor may be configured to detect a target analyte in the liquid component and indicate the presence/concentration of the target analyte. | 12-12-2013 |
20130338453 | AUTOMATIC RECOGNITION OF KNOWN PATTERNS IN PHYSIOLOGICAL MEASUREMENT DATA - A method for analysing physiological measurement values of a user is proposed. The method comprises at least one data acquisition step, wherein, during the data acquisition step, physiological measurement values of the user are acquired at different measurement times and stored in a measurement data record; at least one pattern selection step, wherein, during the pattern selection step, measurement values acquired during one comparison time interval are selected as at least one comparison pattern; and at least one pattern recognition step, wherein, during the pattern recognition step, patterns corresponding to the comparison pattern are sought after in the measurement data record. | 12-19-2013 |
20130338454 | Method and System for Dynamically Updating Calibration Parameters for an Analyte Sensor - Methods and apparatuses including determining a calibration parameter associated with a detected analyte value, calibrating the analyte value based on the calibration parameter, and dynamically updating the calibration parameter are disclosed. Also provided are systems, kits, and computer program products. | 12-19-2013 |
20130338455 | DEVICE FOR MONITORING A MEDICAL PROSTHESIS AND THE HUMAN BODY - A device for monitoring a medical prosthesis and the human body includes a sensor for generating signals depending on surrounding stresses, a processor for processing the signals emitted by the sensor in order to convert the signals into data, a storage device for storing the data, a device for wireless transmission of the stored data, and a supply of electrical energy. The device is included in at least one casing, which is made of biocompatible material and has a device for fixing to a bone. | 12-19-2013 |
20130345526 | Automated Prevention and Control of Epileptic Seizures Using Biochemical And/or Electrical Signal Markers - Methods and medical device systems for preventing or abating seizures, making use of an association between the probability or likelihood of seizure occurrence and the concentrations or activity levels of one or more of putrescine, spermidine, spermine, or γγ-aminobutyric acid (GABA). The concentration or activity level of putrescine, spermidine, spermine, or GABA, or a substrate or enzyme for synthesis thereof, may be determined, and at least one further action may be performed. | 12-26-2013 |
20130345527 | ULTRASOUND BASED ANTIGEN BINDING DETECTION - Embodiments provided here generally relate to combinations of ultrasound aspects and antibodies. In some embodiments, antibodies are immobilized on a surface and binding of the antibodies to antigens can be detected by detecting changes in the vibrational properties of the surface. | 12-26-2013 |
20140012101 | DIRECT DEPLOYMENT SYSTEM AND METHOD - The device and method of the invention generally relate to a system and method to implant an implantable device at a target site. The system comprises a cannula, pushrod, controlled deployment mechanism and said implantable device. The system permits the deposit of an implantable device at a target location in the body by utilizing a controlled amount of force. The devices and methods are particularly well-suited to implantation within the body of a living animal or human to monitor various physiological conditions. | 01-09-2014 |
20140012102 | WEARABLE PATCH COMPRISING MULTIPLE SEPARABLE ADHESIVE LAYERS - Wearable patches comprising multiple separable adhesive layers. One or more of the layers can comprise electronics, mechanical components, gauze, medicine and/or other types of hardware suitable for the intended use of the patch. In use, a first layer of the patch is adhered to a user. When it is time to change layers, the patch is removed from the user, the first layer is removed from the patch to expose a second adhesive layer, and the second layer is applied to the user. The process may be repeated until the remaining layers of the patch have been used. | 01-09-2014 |
20140031643 | HEART FAILURE PATIENTS STRATIFICATION - A system, apparatus and method are provided to quantify a risk of worsening heart failure for subject using at least one physiological sensor circuit such as, for example, a heart sound sensor, a respiration sensor, a cardiac activity sensor, or other sensor circuit. A central tendency measurement of the at least one physiological sensor can be used to quantify the risk of worsening heart failure of the subject. | 01-30-2014 |
20140031644 | Medical Device Insertion - Devices and methods for inserting at least a portion of a medical device in a patient are provided. Embodiments include medical device insertions that employ a plurality of insertion stages. Also provided are systems and kits for use in analyte monitoring. | 01-30-2014 |
20140031645 | STABILIZATION SYSTEM AND ASPIRATION DEVICE WITH RAPID DIAGNOSTICS - A device performs a myringotomy and includes a main body oriented along a central axis. The main body includes an attachment hub for receiving components that provide suction. A hollow positioning member extends at least partially along the central axis, is coupled to the main body and includes a distal end. A cutting edge is located at the distal end of the hollow positioning member and is configured to pierce a tympanic membrane of a body. A sampling chamber is coupled to the main body for collecting at least a portion of the fluid located behind the tympanic membrane of the body using the components that provide suction at the attachment hub. A diagnostic indicator is housed in the sampling chamber and includes a visible indication of a test outcome when exposed to the fluid collected in the sampling chamber. | 01-30-2014 |
20140039280 | Non-Invasive Diagnostic Device for Early Detection of Infection and Inflammation and Methods of Use - The present disclosure provides, in part, a self-contained, point-of-care device for the early detection of infection, or other pathologic conditions that can lead to system inflammation, by the detection of the endogenous gaseous mediator nitric oxide (NO.) and methods of use. | 02-06-2014 |
20140039281 | GASTRIC BANDING SYSTEM ADJUSTMENT BASED ON A SATIETY AGENT CONCENTRATION LEVEL - Methods and devices are provided for adjusting a gastric band to obtain a predetermined optimal expression of hormones. These hormones may be used to control appetite, metabolism and other weight control mechanisms. Ultimately, weight-loss efficacy is desired by tightening or loosening the gastric band based on hormone response. | 02-06-2014 |
20140046146 | ANALYSIS & CLEARING MODULE, SYSTEM AND METHOD - Modules, systems and methods for clearing substances from a living body are disclosed. A module may include an instructions receiver configured to receive wireless transmissions of instructions from a master controller located outside of the body when the module is inside the body; an energy receiver configured to receive wireless transmission of non-destructive energy from the master controller located outside of the body when the module is inside the body; an energy converter configured to convert the non-destructive energy received to destructive energy; and an energy emitter configured to emit the destructive energy. | 02-13-2014 |
20140046147 | Pharmaceutical Dosages Delivery System - Pharmaceutical delivery systems for delivering dosages according to the present invention include a carrier component and a cap configured to seal an internal volume of the carrier component, wherein the cap includes a device that produces a unique current signature. Dosages prepared to be delivered according to embodiments of the invention find use in a variety of different applications, including clinical trials. | 02-13-2014 |
20140051950 | USE OF BIOMARKERS AND THERAPEUTIC AGENTS WITH SURGICAL DEVICES - Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation). | 02-20-2014 |
20140058222 | DATA TRANSFER DEVICE AND DATA TRANSFER SYSTEM - A device for receiving a transmitting unit that is detachably attachable to a sensor unit configured to be placed on a subject to acquire a biosignal of the subject and that acquires bio-information from the biosignal acquired in the sensor unit to transmit the biosignal to an external device. This device has first and second ports on which transmitting units can be placed, and communication sections each provided in a respective one of the ports to carry out communication with the transmitting units mounted on the respective ports. When the transmitting unit is newly mounted on one port, the device acquires transmission data including communication identification information for the transmission from the newly mounted transmitting unit by the communication section of this port and transmits the acquired transmission data to another transmitting unit already mounted on the other port by using the communication section provided in the other port. | 02-27-2014 |
20140066729 | Sampling Device And System For Capturing Biological Targets Of A Body Fluid, And Process For Manufacturing This Device - The invention relates to a sampling device adapted to be inserted into a hollow tubular endpiece of the needle or catheter type, and to emerge from the endpiece with a view to contact with a bodily fluid containing biological samples to be sampled, to a sampling system incorporating this endpiece and this device, which is mounted so as to slide in the latter, and to a method for manufacturing this device. | 03-06-2014 |
20140066730 | SYSTEM FOR IN-VIVO MEASUREMENT OF AN ANALYTE CONCENTRATION - The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display. | 03-06-2014 |
20140088381 | FACILITATION OF TEAR SAMPLE COLLECTION AND TESTING USING A CONTACT LENS - Apparatus, systems and methods are provided that employ contact lenses that facilitate testing for an analyte present within tear fluid. In an aspect, a contact lens includes a substrate that forms at least part of a body of the contact lens and one or more cavities disposed within the substrate configured to collect and store tear fluid over time when the contact lens is worn over an eye. In another aspect, a contact lens includes a substrate that forms at least part of a body of the contact lens and one or more receptors disposed on or within the substrate, the one or more receptors are configured to bind to a known ligand. | 03-27-2014 |
20140088382 | Health Management Devices and Methods - Methods and devices and systems including a communication module operatively coupled to a data collection module for communicating the stored analyte related data after the analyte related data is stored in the data collection module over a predetermined time period, and a user interface unit configured to communicate with the communication module to receive from the communication module the stored analyte related data in the data collection module over the predetermined time period, and to output information associated with the monitored analyte level, where the user interface unit is configured to operate in a prospective analysis mode including substantially real time output of information associated with the monitored analyte level, or a retrospective analysis mode including limited output of information during the predetermined time period wherein no information related to the monitored analyte level is output during the predetermined time period, are provided. | 03-27-2014 |
20140094665 | URINE BAG FOR COLLECTING BODY FLUIDS - A bag for collecting body fluids, such as urine or vomit, wherein the bag in compact condition includes a front side, a back side, a bottom and at least two side edges, where a bag opening is formed opposite the bottom. The bag includes an expandable bead arranged in or close to the bag opening to keep the bag open. The bead can have several chambers that can be inflated or expanded by a resiliently deformable material arranged in the chambers. A removable absorbing material is arranged at the bottom of the bag so that a sample of the fluid can be taken before it is absorbed. At least a part of the sides of the bag can be transparent. Identification means can be provided to enable identification of the user whose liquid has been collected. The bag and the bead can be compressed and stored in compact condition. | 04-03-2014 |
20140121480 | Sensitivity Calibration of In Vivo Sensors Used to Measure Analyte Concentration - Methods, devices, systems, and computer program products are provided to improve sensitivity calibration of an in vivo analyte sensor and usability of an associated analyte monitoring system. In certain embodiments, methods are provided that improve the user experience of using an analyte monitoring system. Certain embodiments of the present disclosure include features that reduce the amount of calibration or re-calibration performed by the analyte monitoring system. More specifically methods of using a suspect calibration attempt to avoid having to recalibrate by adjusting the calibration or mitigating effects of sensor signal attenuation that caused the calibration attempt to be suspect are provided. Additional features are disclosed. | 05-01-2014 |
20140128693 | Systems and Methods for Transdermal Secretion Detection - Various embodiments of the present invention provide systems and methods for detecting chemicals. As an example, a system is disclosed that includes a chemical sensor, a processor, and a computer readable medium. The computer readable medium includes instructions executable by the processor to: receive a plurality of outputs from the chemical sensor; calculate a baseline value using the plurality of outputs from the chemical sensor; and report an event when the baseline value is exceeded. | 05-08-2014 |
20140135599 | Analyte measurement device with a single shot actuator - An analyte and detecting apparatus includes a housing, an access door and a front end aperture. A module is positionable in the housing. A penetrating member is positioned in the module and upon launch passes through the front end aperture. An analyte sensor is positioned in the module. A penetrating member driver is configured to be coupled to the penetrating member. A mechanism is included that moves an arm coupled to the penetrating member driver into a launch position and allows motion of the penetrating member driver. | 05-15-2014 |
20140142399 | NONINVASIVE MULTI-PARAMETER PATIENT MONITOR - Embodiments of the present disclosure include a handheld multi-parameter patient monitor capable of determining multiple physiological parameters from the output of a light sensitive detector capable of detecting light attenuated by body tissue. For example, in an embodiment, the monitor is capable of advantageously and accurately displaying one or more of pulse rate, plethysmograph data, perfusion quality, signal confidence, and values of blood constituents in body tissue, including for example, arterial carbon monoxide saturation (“HbCO”), methemoglobin saturation (“HbMet”), total hemoglobin (“Hbt”), arterial oxygen saturation (“SpO2”), fractional arterial oxygen saturation (“SpaO2”), or the like. In an embodiment, the monitor displays a line associated with a patient wellness level. | 05-22-2014 |
20140148659 | Methods, Devices, and Systems Related to Analyte Monitoring - Generally, methods, devices, and systems related to analyte monitoring and data logging are provided—e.g., as related to in vivo analyte monitoring devices and systems. In some aspects, methods, devices, and systems are provided that relate to enable related settings based on an expected use of an in vivo positioned sensor; logging or otherwise recording analyte levels acquired or derived—e.g., sample analyte levels more frequently than they are logged or otherwise recorded in memory; dynamically adjust the data logging frequency; randomly determine times of acquiring or storing analyte levels from the in-vivo positioned analyte sensors; and enable recording related settings when the system is operable. | 05-29-2014 |
20140148660 | Laser source unit, control method thereof, photoacoustic image generation apparatus and photoacoustic image generation method - Using a laser source unit, a plurality of wavelengths are switched at a high speed without increasing a rotation speed of a birefringent-filter. A Q switch and a birefringent filter are inserted into an optical resonator including a pair of mirrors facing each other with a laser rod interposed therebetween. The birefringent-filter changes an oscillation wavelength of the optical resonator in association with rotational displacement. Driving unit reciprocatively rotates the birefringent-filter in a predetermined range including a discontinuous point of change characteristics of a transmission wavelength for the rotational displacement. An emission control unit irradiates the laser rod with excitation light from a flash lamp, and then turns on the Q switch at a timing when a rotational displacement position of the birefringent-filter is set to a position corresponding to the wavelength of the pulse laser beam to be emitted, to cause the pulse laser beam to be emitted. | 05-29-2014 |
20140155711 | Medical Device Comprising Illumination Arrangement - The present invention relates to a medical device for intradermal or subcutaneous treatment of a patient, comprising: a piercing element to penetrate a skin portion of the patient; an illumination arrangement to illuminate the piercing element and/or to illuminate the skin portion prior and/or during a treatment process, wherein the illumination arrangement is further adapted to visually indicate a predefined treatment sequence of the treatment process. | 06-05-2014 |
20140163338 | Analyte Sensor with Slot Antenna - A medical device for detecting at least one analyte in a body fluid is disclosed. The medical device includes at least one implantable functional element and at least one driver having at least one electronic component. The functional element is connectable to the driver. The driver includes a housing having at least one metal housing and at least one wireless communication device. The metal housing has at least one slot structure. The communication device is adapted to communicate through the slot structure with an external apparatus. | 06-12-2014 |
20140163339 | DRUG DELIVERY DEVICE - Embodiments of the present invention provide drug-delivery devices comprising a drug reservoir chamber containing a substance to be delivered, in fluid connection with a drug administration means, and at least one displacement-generating battery cell coupled to said drug reservoir chamber by a coupling means, the at least one displacement-generating battery cell comprising an element that changes shape as a result of discharge of the battery cell so as to cause a displacement within the battery unit, the arrangement being such that the displacement derived from said battery unit is conveyed by said coupling means to cause displacement of at least a portion of a wall of said drug reservoir chamber reducing the volume of said drug reservoir chamber such that said substance is expelled from said drug reservoir chamber towards said drug administration means upon discharge, thereby being a self-powered drug delivery device. | 06-12-2014 |
20140163340 | FLUID MANAGEMENT AND PATIENT MONITORING SYSTEM - A lactate sensor arrangement includes a catheter for withdrawing a test fluid sample, a sensor module for measuring an analyte such as lactate in the sample, and a pumping mechanism. A single uninterrupted flow path extends between the pumping mechanism and the catheter and within the flow path resides a sensor module containing a test chamber. The sensor arrangement also includes a control unit or controller that interfaces with a pumping mechanism driver. The sensor arrangement also includes a source of sensor calibration and anticoagulant solution, such as a reservoir. | 06-12-2014 |
20140163341 | BIOLOGICAL TEST KIT - The biological test kit is a device for drawing and, optionally, testing biological samples. The biological test kit is an array of lancets set in wells in a rigid base. Each lancet well is covered by a protective cover which when deformed permits the lancet to puncture a user or other patient. In one embodiment the biological test kit employs distinct covers for each lancet and in another the covers are formed from sheet material formed into blisters which cover the lancet. | 06-12-2014 |
20140171760 | SYSTEMS AND METHODS FOR REDUCING OR PREVENTING BACKFLOW IN A DELIVERY SYSTEM - Systems and methods are disclosed herein that generally involve CED devices with various features for reducing or preventing backflow. In some embodiments, CED devices include a tissue-receiving space disposed proximal to a distal fluid outlet. Tissue can be compressed into or pinched/pinned by the tissue-receiving space as the device is inserted into a target region of a patient, thereby forming a seal that reduces or prevents proximal backflow of fluid ejected from the outlet beyond the tissue-receiving space. In some embodiments, CED devices include a bullet-shaped nose proximal to a distal fluid outlet. The bullet-shaped nose forms a good seal with surrounding tissue and helps reduce or prevent backflow of infused fluid. | 06-19-2014 |
20140187876 | SENSOR INSERTING DEVICE AND OPERATING METHOD THEREOF - The sensor inserting device includes a device body, a movement mechanism which inserts a detector and an insertion needle into a body of a patient by moving a sensor with the insertion needle, and a dwelling member which is arranged on a moving path of the sensor and attached to the sensor by movement of the sensor caused by the movement mechanism. The dwelling member is allowed to dwell on the skin of the patient with the sensor and the transmitter connected at a location in which the detector is inserted into the body of the patient. | 07-03-2014 |
20140194706 | IN-SITU TEAR SAMPLE COLLECTION AND TESTING USING A CONTACT LENS - Apparatus, systems and methods employing contact lenses having one or more sensor that sense an analyte in tear fluid and one or more recesses that collect the tear fluid. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a recess formed within the substrate configured to collect tear fluid when the contact lens is worn. The contact lens further includes at least one sensor disposed within the substrate configured to sense presence of an analyte in the collected tear fluid. | 07-10-2014 |
20140206958 | WIRELESS DEGRADATION DATA GENERATOR FOR USE WITH A THERAPEUTIC SCAFFOLD AND METHODS FOR USE THEREWITH - A degradation data generator is used with a scaffold for delivery within a patient. The degradation data generator includes a driving circuit electrically coupled to drive an impedance of the scaffold. A detection circuit generates degradation data based on the impedance of the scaffold or other properties such as RF or lightwave transmission, conductance or absorption. The degradation data indicates an amount of biodegradation of the scaffold. A wireless transmitter is coupled to transmit the degradation data to a wireless degradation data receiver, while the scaffold is within the patient. | 07-24-2014 |
20140206959 | TRANSCEIVER UNIT IN A MEASUREMENT SYSTEM - A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the senior wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module. | 07-24-2014 |
20140221792 | Hydration Monitoring Apparatus - A hydration monitoring apparatus is disclosed. The hydration monitoring apparatus comprises at least one sensor and an analysis unit. The hydration monitoring apparatus may take at least one biometric, biological, and/or physiological measurement of an individual and measures the hydration level, dehydration level or status, or bodily fluid level of an individual. The hydration monitoring apparatus indicates the hydration level, dehydration level or status, or bodily fluid level of an individual based on one or more biometric, biological, and/or physiological measurements. In one embodiment of the invention, the hydration monitoring apparatus determines whether to inform the user of their hydration level, dehydration level or status, or bodily fluid level. In one embodiment the hydration monitoring apparatus further comprises an informing device that informs the individual that the individual is approaching dehydration. | 08-07-2014 |
20140221793 | CONTAINER FOR TESTING BLOOD AND BLOOD DRAWING INSTRUMENT - Provided is a container for testing blood ( | 08-07-2014 |
20140235970 | ASSEMBLY FOR DETERMINING THE PRESENCE OR ABSENCE OF AN ANALYTE IN A BLOOD SAMPLE AND ANALYSIS UNIT COMPRISING SUCH AN ASSEMBLY - This assembly includes: a transportable support; a strip attached to the support and including an application area for applying the sample and at least one reagent required for the analysis; a piercing member for piercing the skin and a blood vessel; and a container for collecting, storing and returning the sample of human or animal blood. The piercing member is inserted into the container. The tip is connected to the support. The container is connected to the support in a removable manner between a storage configuration and a use configuration, in which the container is placed close to the application area. | 08-21-2014 |
20140235971 | DETECTING A VASOACTIVE AGENT IN THE BLOODSTREAM - A system and method are disclosed for detecting a vasoactive agent in patient's bloodstream. In one embodiment, an input signal is received that is associated with arterial blood pressure. A change of an arterial blood pressure parameter over time is determined. A vasoactive agent is then automatically detected using the determined change. In another embodiment, a waveform associated with an arterial blood pressure signal can be received. A parameter associated with the received waveform is calculate. Then the calculated parameter can be used to determine the presence of a vasoactive agent. In yet another embodiment, detection of a vasoactive agent in any of the other embodiments can be used in a calculation of a hemodynamic parameter, such as cardiac output, stroke volume, systemic vascular resistance, stroke volume variation, cardiac index, stroke volume index, systemic vascular resistance index, vascular compliance, and vascular tone. | 08-21-2014 |
20140249387 | On-Body Medical Device Securement - Devices and methods for maintaining a medical device on-body are provided. Embodiments include medical device securement systems having first and second on-body securement elements. Also provided are systems and kits for use maintaining a medical device on-body. | 09-04-2014 |
20140249388 | METHOD AND APPARATUS TO SENSE HYDRATION LEVEL OF A PERSON - A hydration sensor or sensing element is configured to measure the hydration level of a user. The sensing element can include a water-permeable material positioned in between two water-impermeable material. The sensing element can be coupled to a bottle of fluid, or a carrier with a timer. The sensing element can be incorporated into a handheld device. The sensing element can be a disposable element, an element applicable for more than one-time use, or a re-usable element. The sensing element or sensor can be calibrated for a specific user or a group of users. One or more additional sensors that do not measure hydration level of the user can be coupled to a hydration sensing element to determine the amount of fluid consumption for the user in different conditions. | 09-04-2014 |
20140249389 | METHOD AND APPARATUS FOR TREATING SKIN PRIOR TO BIOSENSOR INSERTION - Embodiments of the present invention provide a device and method for treating animal skin to produce tautness in the skin during the insertion of an analyte sensor. A device in accordance with embodiments of the present invention includes a housing that partially encloses a cavity and is adapted for mounting onto animal skin and a sensor insertion module adapted to insert an analyte sensor through animal skin. | 09-04-2014 |
20140257059 | Optimizing Analyte Sensor Calibration - Method and apparatus for optimizing analyte sensor calibration including receiving a current blood glucose measurement, retrieving a time information for an upcoming scheduled calibration event for calibrating an analyte sensor, determining temporal proximity between the current blood glucose measurement and the retrieved time information for the upcoming calibration event, initiating a calibration routine to calibrate the analyte sensor when the determined temporal proximity is within a predetermined time period, and overriding the upcoming scheduled calibration event using the current blood glucose measurement are provided. | 09-11-2014 |
20140275863 | FLUID ANALYSIS DEVICE AND RELATED METHOD - A device and method for analyzing characteristics of a fluid. The device is a bolus arranged to remain within the fluid for the analysis. The bolus includes a sensor module, a fluid analysis module, a fluid pumping module and a control and data transmission module. The sensor module includes a transducer element to generate acoustic signals and convert acoustic signals. The information derived from generating and receiving acoustic signals is used to obtain information about constituents and conditions of the fluid. That information may be transferred to a near or remote location for analysis. The device and analysis method are suitable for evaluating the health of animals. The device may be used in a telemedicine environment at an animal health facility. It may also be uploaded to a database for use in the analysis of a group of sources of fluid, such as a herd of cows. | 09-18-2014 |
20140275864 | Polyurethane dressing and method for making same - The present invention is directed toward a wound dressing comprising a foam body made of polyurethane material treated with a plurality of colored biocidal dyes with at least one of the dyes being gram positive and at least one of the dyes being gram negative to dye the body a distinct color. The body has at least one planar surface and ranges from about 1 mm to about 10 mm in thickness and has an outer film cover and border with a hydrogel adhesive secured to the body. The foam body changes color when placed in contact with an infected wound site. | 09-18-2014 |
20140275865 | SHEATHED RIVET - The device and method of the invention generally relate to a system and method for percutaneous delivery, implantation and securement of an anchor at a target site. The system comprises an anchor having a bridge, a first stabilizer having a crimped state and a deployed state, a second stabilizer having a crimped state and a deployed state, and a positioning arm. The system may further comprise a cannula, pushrod, and sheath. The system permits the deposit of an anchor at a target location in the body by utilizing a controlled amount of force. The anchors and methods are particularly well-suited to implantation within the body of a living animal or human to monitor various physiological conditions. | 09-18-2014 |
20140275866 | ROTATABLE DISK-SHAPED FLUID SAMPLE COLLECTION DEVICE - A sample collection device for a fluid includes: a substantially disk-shaped body having a periphery; a capillary channel extending through the body and bounded by the periphery, having a first end and a second end, wherein the first end is adapted to draw the fluid into the channel by capillary action; a sample collection well located in the vicinity of the second end and in fluid communication with the capillary channel; and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the major surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge having a housing comprising an air vent in fluid communication with the capillary channel when the disk is rotated in a first position. | 09-18-2014 |
20140288398 | COMPOSITIONS AND DEVICES FOR THE DETECTION OF BIOMARKERS IN THE GASTROINTESTINAL TRACT AND METHODS FOR MAKING AND USING THEM - In alternative embodiments, the invention provides compositions such as devices, pills, beads, capsules, products of manufacture, particles, microparticles, nanoparticles, gels, liquid gels, liquid gel capsules, capsules, tablets, geltabs, liquids, sprays, emulsions, suspensions, pastes or yogurts, for the detection and isolation of biomarkers, nucleic acids, proteins or peptides, proteoglycans, lipids, fats, sugars or polysaccharides in the gastrointestinal tract for e.g., detecting the presence of particular exogenous or endogenous nucleic acids, e.g., DNA or RNA, or proteins, in the gastrointestinal tract, for example, to diagnose the presence of an infectious or exogenous agent such as a virus, a fungus, a parasite, a bacteria, intestinal helminths and protozoan parasites, and the like, or a biomarker such as a cancer-causing or cancer-predisposing allele, e.g., mutations of the KRAS2 oncogene in pancreatic cancer. In alternative embodiments, compositions of the invention comprise magnetic particles such as a magnetically-responsive microparticle or nanoparticle; a superparamagnetic bead or polystyrene bead; a superparamagnetic fine particle; a ferrimagnetic particle; or, a magnetic microsphere, nanosphere, microbead or nanobeads. In alternative embodiments, the invention provides methods for detecting, retrieving, capturing or isolating a sample of a nucleic acid, or an anionic, cationic or hydrophobic protein or peptide, a mucin, a phosphoprotein, a proteoglycan or a polysaccharide, in vivo. | 09-25-2014 |
20140288399 | Medical Apparatus Having Infusion and Detection Capabilities - A medical apparatus for supplying a medication fluid into an organism and for detecting a substance of the organism is disclosed. The medical apparatus has a casing, cannula, and an insertion needle. The casing has a chamber accommodating the medication fluid and an opening in fluid communication with the chamber. The cannula has a lumen in fluid communication with the chamber. The insertion needle has a receptacle. A portion of the insertion needle is removably arrangeable with the lumen. The receptacle is configured to at least partially receive a sensor system for detecting the substance of the organism. A seal is adapted to annularly sealingly surround a portion of the sensor system when the insertion needle is removed from the opening and the portion of the sensor system is arranged in the opening. | 09-25-2014 |
20140296663 | BREAST IMPLANT WITH COVERING AND ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source. | 10-02-2014 |
20140303461 | APPARATUS AND METHODS FOR ACCESSING THE LYMPHATIC SYSTEM - Systems and methods are provided for performing a medical procedure within a patient's body that involves a thoracic duct including an ostium communicating with the patient's venous system. A distal end of a catheter is introduced through the patient's venous system into a body lumen adjacent the ostium of the thoracic duct. An expandable member on the distal end of the tubular member may be expanded adjacent the ostium, e.g., within the body lumen or the thoracic duct itself, and used to isolate the thoracic duct from the body lumen, whereupon a medical procedure may be performed via the thoracic duct. For example, lymphatic fluid may be removed from the thoracic duct through a lumen of the tubular member and/or one or more agents may be introduced into the thoracic duct through the tubular member. | 10-09-2014 |
20140316223 | PROTECTIVE CONTAINER FOR HOLDING REUSABLE DIAGNOSTIC COMPONENTS - A protective container for holding a reusable control part of a transcutaneous sensor system for detecting at least one analyte in a bodily fluid is disclosed. The control part includes at least one coupling, which has at least one sensor coupling for connection to at least one transcutaneous sensor. The protective container has at least one container housing. The control part can be held in the container housing. The container housing is adapted to shield the control part from environmental influences. The container housing also has at least one connector which can be connected to the coupling and seals the latter in a media-tight fashion. | 10-23-2014 |
20140343379 | METHOD AND DEVICE FOR MONITORING OPHTHALMIC LENS MANUFACTURING CONDITIONS - A method and communication system for ophthalmic device manufacturing line is disclosed. More specifically, the communication device may be incorporated in early stages of manufacturing of the ophthalmic device to monitor process controls without delay. In some embodiments, a unique pedigree profile can be stored for an ophthalmic device during manufacturing and correlated with one or more of: design profiles, controlled process parameters, performance, and distribution channels. | 11-20-2014 |
20140343380 | Correlating Sensor Data Obtained from a Wearable Sensor Device with Data Obtained from a Smart Phone - Sensor data obtained from a wearable sensor device can be correlated with sensor data obtained from a smart phone or other mobile device. The correlation of the data from the two sources can enable the determination of why a person performs some action during sleep. In a particular example, motion data obtained from a wearable sensor device can be correlated with audio or visual data obtained by a sensor on a smart phone. In this way, it can be determined whether a person moved in response to a sound or light perceived during sleep. Additionally, the correlation of the data from the two sources can also provide additional information about how a user performs an activity such as exercise. | 11-20-2014 |
20140357967 | Detection Device for the In Vivo and/or In Vitro Enrichment of Sample Material - The invention relates to a detection device for the in vivo and/or in vitro enrichment of sample material, comprising a functional surface charged with detection receptors. To ensure the diagnosis of different diseases using a detection device of the type mentioned at the outset with less efforts and an improved precision of the diagnosis, it is provided according to the invention that the detection device comprises at least one guide element and at least two functional elements disposed at the guide element, wherein a functional surface charged with detection receptors is formed at each of them, the functional elements being designed for being detachable from each other and/or individually detachable from the guide element. Furthermore, the invention provides a use of and a method for the application of said detection device. | 12-04-2014 |
20140357968 | SYSTEM AND METHOD FOR NEUROTRANSMITTER MEASUREMENT - Embodiments of the presently-disclosed subject matter include methods and systems for measuring a level of a neurotransmitter in a subject. Embodiments of the present methods comprise displaying a fixation point, a reward target, and a non-reward target, and measuring one or more saccade movement parameters for reward saccades and non-reward saccades. The saccade movement parameters can include velocity, amplitude, reaction time, or a combination thereof. The present methods can further include determining a reward modulation of the subject, the reward modulation being equal to a difference between the reward and the non-reward values for a respective saccade movement parameter. Some embodiments further include identifying the subject as including a deficiency of the neurotransmitter if there is a statistically measurable difference between the reward modulation of the subject and a reference reward modulation and/or if the non-reward and the reward saccade movement parameters are statistically equivalent. | 12-04-2014 |
20140378790 | METHODS AND DEVICES FOR DELIVERING AND MONITORING OF TOBACCO, NICOTINE, OR OTHER SUBSTANCES - Methods, systems, and devices are described for providing risk evaluation and mitigation strategies for use with modified risk products or other tobacco products, and in particular, associated with nicotine and tobacco products. | 12-25-2014 |
20150011847 | Blood Sampling Tube with Integrated Sensor Device - A blood-sampling tube with a first fluid-receiving chamber for receiving a fluid is described, where the first fluid-receiving chamber may be connected to at least one fluid channel that has a sensor device for measuring at least one biochemical function of the fluid passed through the fluid channel, where the measured biochemical function of the fluid may be read out from the sensor device via a data interface of the blood-sampling tube. | 01-08-2015 |
20150018639 | Method and System for Providing an Integrated Analyte Sensor Insertion Device and Data Processing Unit - Method and apparatus for providing an integrated analyte sensor and data processing unit assembly is provided. | 01-15-2015 |
20150018640 | Method and Apparatus for Providing Analyte Sensor Insertion - Devices and methods for positioning a portion of a sensor at a first predetermined location, displacing the portion of the sensor from the first predetermined location to a second predetermined location, and detecting one or signals associated with an analyte level of a patient at the second predetermined location are disclosed. Also provided are systems and kits for use in analyte monitoring. | 01-15-2015 |
20150025338 | Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. | 01-22-2015 |
20150031968 | SYSTEM AND METHOD FOR MONITORING PLEURAL FLUID - The disclosure is directed to intrapleural air leak detection and monitoring. According to various embodiments of the disclosure, an air leak may be detected utilizing at least one sensor to determine whether fluid extracted from a pleural cavity of a patient includes carbon dioxide and/or a second substance. The second substance may be a foreign substance inhaled by the patient to confirm presence of the air leak. The air leak may be further monitored over a period of time by collecting temporally successive measurements associated with detected concentrations of carbon dioxide. Therefore, tissue damage and recovery may be assessed according to objectively collected criteria. | 01-29-2015 |
20150045635 | CO-PLANAR, NEAR FIELD COMMUNICATION TELEMETRY LINK FOR AN ANALYTE SENSOR - An inductive sensor system for remote powering and communication with an analyte sensor (e.g., a fully implantable analyte sensor). The system may include an analyte sensor and transceiver. The system may be ferrite-enhanced. The transceiver may implement a passive telemetry for communicating with the analyte sensor via an inductive magnetic link for both power and data transfer. The link may be a co-planar, near field communication telemetry link. The transceiver may include a reflection plate configured to focus flux lines linking the transceiver and the sensor uniformly beneath the transceiver. The transceiver may include an amplifier configured to amplify battery power and provide radio frequency (RF) power to a transceiver antenna. | 02-12-2015 |
20150051457 | SENSOR INSERTION DEVICE AND METHOD FOR OPERATING SAID DEVICE - A sensor inserting device includes a device main body and a push handle for moving a detector of a sensor and an insertion needle, with the sensor held coupled to the insertion needle, into the body of a patient. A transmitter, for processing a signal from the sensor, is set in the device main body. A cable, allowing transmission of a signal between the sensor and the transmitter, is connected to the sensor ( | 02-19-2015 |
20150057509 | DRUG ELUTION FOR IN VIVO PROTECTION OF BIO-SENSING ANALYTES - A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more therapeutic agents. The one or more therapeutic agents may reduce deterioration of the analyte indicator. The one or more therapeutic agents may be incorporated within the analyte indicator, a membrane covering at least a portion of the analyte indicator, and/or one or more drug eluting polymer matrices, which may be external to or within the sensor housing. | 02-26-2015 |
20150057510 | PATIENT-ENACTED SAMPLING TECHNIQUE - The present invention is generally directed to systems and methods for sampling fluids from subjects. The fluid may be any suitable bodily fluid, e.g., blood or interstitial fluid. In some cases, the subject is a patient. The subject may have a device that can be applied to the skin of the subject (e.g., by the subject, or another person), and the device is able to obtain a sample of fluid. The fluid may be stored within a reservoir in the device, and the fluid may be obtained from the subject at any convenient time, e.g., at home, away from a healthcare setting, etc. In some embodiments, the device, or a portion thereof, may be returned to a clinical and/or laboratory setting to analyze the fluid stored within the device. | 02-26-2015 |
20150065820 | Sacrificial Layers for Bio-Compatible Devices - A method may involve: forming a sacrificial layer on a working substrate; forming a first bio-compatible layer on the sacrificial layer such that the first bio-compatible layer adheres to the sacrificial layer; forming a conductive pattern on the first bio-compatible layer; mounting an electronic component to the conductive pattern; forming a second bio-compatible layer over the first bio-compatible layer, the electronic component, and the conductive pattern; and removing the sacrificial layer to release the bio-compatible device from the working substrate. The first bio-compatible layer defines a first side of a bio-compatible device. The second bio-compatible layer defines a second side of the bio-compatible device. | 03-05-2015 |
20150065821 | Nanoparticle Phoresis - Functionalized particles in the blood are able to selectively bind to targets in the blood that have adverse health effects. The binding of the particles to the targets allows the targets to be selectively modified or destroyed by energy from outside the body such that the adverse health effects are reduced or eliminated. The energy is generated by a wearable device which is able to direct the energy into the subsurface vasculature of the wearer of the wearable device. Further, one or more of the functionalized particles may be magnetic, allowing a magnetic field generated by the wearable device and directed into the subsurface vasculature to concentrate the bound targets in a lumen of the subsurface vasculature proximate to the wearable device. | 03-05-2015 |
20150065822 | SYSTEMS AND METHODS FOR ADDICTION PREVENTION AND TREATMENT - The invention pertains to systems and methods for preventing or reducing the probability of human addiction to various substances and/or treating those currently or previously addicted to substances. The invention includes a sensing mechanism to detect a presence of the addictive substance or a condition resulting from the presence of the addictive substance, a signaling mechanism to generate a signal as a result of the sensing mechanism detecting the presence of the addictive substance or a condition resulting from the presence of the addictive substance, and a receiving mechanism to provide at least one response as a result of receiving as input the signal generated by the signaling mechanism | 03-05-2015 |
20150080684 | SENSOR INSERTION ASSEMBLY, SENSOR CARTRIDGE, AND INSERTER - A sensor insertion assembly comprising a sensor cartridge having an insertion needle and a sensor within a sterile capsule. The sensor insertion assembly further comprises an inserter comprising a chamber for receiving the sensor cartridge, wherein the inserter further comprises an insertion mechanism operable for actuating the insertion needle for inserting the sensor into a subject. The sensor cartridge is removable from the chamber. The sensor cartridge is operable for shielding the insertion needle upon removal of the sensor cartridge from the chamber. | 03-19-2015 |
20150087935 | Real-time blood detection system - Disclosed is a system for real-time detection and annunciation of blood associated with menstruation and surgical wounds. The system comprises blood detection means, communication means for relay of blood detection information, and annunciation means to inform the user of the emanation of blood. Various system embodiments include local and remote as well as covert and non-covert annunciation to users or medical personnel, various forms of real-time blood detection sensors, blood analysis capability, and smart bandage telemetry. | 03-26-2015 |
20150087936 | PHYSIOLOGICAL PARAMETER SYSTEM - A physiological parameter system has one or more parameter inputs responsive to one or more physiological sensors. The physiological parameter system may also have quality indicators relating to confidence in the parameter inputs. A processor is adapted to combine the parameter inputs, quality indicators and predetermined limits for the parameters inputs and quality indicators so as to generate alarm outputs or control outputs or both. | 03-26-2015 |
20150112166 | In Vivo Technology System for Human Gut Research, Diagnostics and Treatment - A comprehensive system for gut in vivo exploration, discovery, characterization, research, diagnostics, and treatment comprising three different ingestible capsules and their associated methodologies, is provided for medical research and patient care. The system of tools is focused on discovery of causes of gut-based illnesses, treating, and curing them. The capsules perform unique functions, and as an in vivo healthcare system, provide for sampling, testing or diagnosing gut processes as a function of the length of the gut “x” and at any point in time “t”, including simultaneous chemical substance sampling and testing, along with the associated microbes. The in vivo system allows medications or system perturbation substances delivery, in a prescribed manner to the point of interest, and the resulting substances and microbes are simultaneously sampled upstream and downstream at the exact point and time of delivery. The system provides for microbes and associated chemical substances and gut digestion processes sampling with such detail and resolution as to permit quantitative system modeling and profiling of many aspects of the GI tract over its entire length. Likewise as a system, it simplifies gut analysis and diagnosis by reducing the number of variables from thousands to a manageable number for researchers, or physicians to deliver very specific patient care. The 3-capsule system, in conjunction with research and physician applications, generates huge volumes of raw and application data of sufficient numbers to utilize any gut characterization or modeling method, including that associated with Big Data. As a system, it is an enabling technology and catalyst for new educational and research institutions, businesses, industries, and the development of new complementary technologies. | 04-23-2015 |
20150112167 | Non-Invasive Analyte Detection System with Modulation Source - A system for modulating a response signal includes functionalized particles configured to interact with target analytes, a detector configured to detect an analyte response signal transmitted from the body, a modulation source configured to modulate the analyte response signal, and a processor configured to non-invasively detect the one or more target analytes by differentiating the analyte response signal from a background signal, at least in part, based on the modulation. The analyte response signal is related to the interaction of the target analytes with the functionalized particles. In some examples, the system may also include magnetic particles and a magnetic field source sufficient to distribute the magnetic particles into a spatial arrangement in the body. The analyte response signal may be differentiated from the background signal, at least in part, based on modulation of the signals due, at least in part, to the spatial arrangement of the magnetic particles. | 04-23-2015 |
20150112168 | Spatial Modulation of Magnetic Particles in Vasculature by External Magnetic Field - A method for modulating a response signal includes introducing functionalized magnetic particles configured to interact with target analytes into the body, applying a magnetic field sufficient to draw the functionalized magnetic particles towards a surface of the lumen of subsurface vasculature closest to an internally or externally applied mask having a spatial arrangement, and detecting a response signal, which includes a background signal and an analyte response signal, transmitted from the subsurface vasculature. The analyte response signal related to interaction of the functionalized magnetic particles with the target analytes and is modulated with respect to the background signal due, at least in part, to the spatial arrangement of the mask. The target analytes may be non-invasively detected by differentiating the analyte response signal from the background signal due, at least in part, to the modulation of the analyte response signal. | 04-23-2015 |
20150119660 | Medical Apparatus Having Infusion and Detection Capabilities - A medical apparatus for supplying a medication fluid into an organism and for detecting a substance of the organism is disclosed. The medical apparatus has a casing, cannula, and an insertion needle. The casing has a chamber accommodating the medication fluid and an opening in fluid communication with the chamber. The cannula has a lumen in fluid communication with the chamber. The insertion needle has a receptacle. A portion of the insertion needle is removably arrangeable within the lumen. The receptacle is configured to at least partially receive a sensor system for detecting the substance of the organism. A seal is adapted to annularly sealingly surround a portion of the sensor system when the insertion needle is removed from the opening and the portion of the sensor system is arranged in the opening. | 04-30-2015 |
20150126828 | BLOOD SAMPLING - Provided herein is technology relating to sampling blood and particularly, but not exclusively, to methods, devices, and systems for high-efficiency isolation of analytes from blood, e.g., for sensitive detection of analytes present in blood at low concentrations. | 05-07-2015 |
20150126829 | MICRO-MAGNETIC REPORTER AND SYSTEMS - The present disclosure describes system and methods for detecting and amplifying weak magnetic fields generated by anatomical structures. The disclosure describes an implantable magnetic reporter system. The magnetic reporter system includes a magnetic reporter. The magnetic reporter includes a platform coupled to a support structure by a plurality of torsional flexures. A magnet is disposed on the platform, and the magnet and platform rotate when exposed to a magnetic field. The rotation of the magnet generates a stronger magnet field that is detectable external to the patient. | 05-07-2015 |
20150141776 | SUBCUTANEOUS NEEDLE INSERTION MECHANISM - A subcutaneous access device has a skin attachment plate coated with an adhesive layer. The skin attachment plate is moveably linked by a retraction mechanism to a needle support with fixedly positioned needles. In the ready-to-use position the skin attachment plate is spaced away from the needle support and covers the fixedly positioned needles. Subcutaneous insertion of the needles is effected by attachment of the skin attachment plate with the adhesive layer to the skin and releasing the retraction mechanism, thus triggering the pulling of the attached skin with high velocity against the tip of the needles. | 05-21-2015 |
20150297097 | VASCULAR ACCESS EVALUATION AND TREATMENT - The present invention generally relates to methods for assessing and treating dysfunctional vascular access sites, such as fistulas and grafts. According to certain aspects, methods of the invention include processing intraluminal image data of a vascular access site to characterize biological material present at the vascular access site, assessing the characterized biological material to identify a condition; and determining a therapeutic mode for treating the condition based on the assessment. | 10-22-2015 |
20150305625 | Flexible and Scalable Sensor Arrays for Recording and Modulating Physiological Activity - An implantable sensor array incorporates active electronic elements to greatly increase the number of sensors and their density that can be simultaneously recorded and activated. The sensors can be of various configurations and types, for example: optical, chemical, temperature, pressure or other sensors including effectors for applying signals to surrounding tissues. The sensors/effectors are arranged on a flexible and stretchable substrate with incorporated active components that allow the effective size, configuration, number and pattern of sensors/effectors to be dynamically changed, as needed, through a wired or wireless means of communication. Active processing allows many channels to be combined either through analog or digital means such that the number of wires exiting the array can be substantially reduced compared to the number of sensors/effectors on the array. | 10-29-2015 |
20150313515 | METHOD AND APPARATUS FOR PENETRATING TISSUE - A body fluid sampling system for use on a tissue site includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. | 11-05-2015 |
20150313522 | DEVICES AND TECHNIQUES ASSOCIATED WITH DIAGNOSTICS, THERAPIES, AND OTHER APPLICATIONS, INCLUDING SKIN-ASSOCIATED APPLICATIONS - The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor. | 11-05-2015 |
20150320920 | CALIBRATION OF A BODY PARAMETER FOR MONITORING DIALYSIS - A method and an apparatus for detecting a change of the fluid status or determining the fluid status of an individual are disclosed. The method comprises the following steps: determining a change of the body parameter (ΔRBV) of the individual during a first treatment session ( | 11-12-2015 |
20150359473 | Catheter Insertion Device with Blood Analyzer - A device and method yielding a blood analysis employable in combination with an introducer for a catheter for a concurrent testing of blood from the introducer flash chamber during placement of a venous catheter. The device employs a colorimetric blood analysis to provide the user a visually discernable alert to the results of tested blood concurrent with the placement of the catheter with the introducer. | 12-17-2015 |
20150374274 | Oral Detection Apparatus - An oral detection device is used for making oral detection of gastroesophageal reflux disease or other diseases or disorders. It includes a sensor, a sensor container, a base and a tooth retainer. The sensor is held in the sensor container and got its orientation maintained towards the esophageal opening. The tooth retainer works to connect the base where the sensor container and the sensor within are secured to, to teeth in either a maxillary style or a mandibular style. In this way, the oral detection device is able to detect gastroesophageal reflux or other targets in mouth in a removable and reusable way. | 12-31-2015 |
20150374299 | Method and Apparatus for Providing Data Processing and Control in a Medical Communication System - Methods and apparatus for providing data processing and control for use in a medical communication system are provided. | 12-31-2015 |
20160000360 | Method and System for Providing Continuous Calibration of Implantable Analyte Sensors - Method and system for providing continuous calibration of analyte sensors includes calibrating a first sensor, receiving data associated with detected analyte levels from the first sensor, and calibrating a second sensor based on a predetermined scaling factor and data associated with detected analyte levels from the first sensor, is disclosed. | 01-07-2016 |
20160007892 | SYSTEMS AND METHODS FOR MEASURING OXYGENATION | 01-14-2016 |
20160007893 | SYSTEMS AND METHODS FOR EARLY DISEASE DETECTION AND REAL-TIME DISEASE MONITORING | 01-14-2016 |
20160007895 | SYSTEMS AND METHODS FOR MEASURING FETAL CEREBRAL OXYGENATION | 01-14-2016 |
20160007896 | METHOD AND APPARATUS FOR IN VIVO SURVEILLANCE OF CIRCULATING BIOLOGICAL COMPONENTS | 01-14-2016 |
20160011290 | Non-Invasive, In-Vivo Measurement of Blood Constituents Using a Portable Nuclear Magnetic Resonance Device | 01-14-2016 |
20160015304 | SYSTEMS AND METHODS FOR MEASURING OXYGENATION - Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary. | 01-21-2016 |
20160015938 | Head Mounted IV Holder Assembly and Method of Use - A head mounted catheter holder assembly is disclosed comprising a head mount assembly and an one or more catheter holders. Said one or more catheter holders comprises a first catheter holder. Said one or more catheter holders attach to said head mount assembly. Said head mount assembly releasably attaches to a head of a user. Said one or more catheter holders releasably hold a one or more catheter tubes. | 01-21-2016 |
20160022188 | SPACE-SAVING MAGAZINING OF ANALYTICAL AIDS - An analytical magazine is proposed, which comprises a plurality of analytical aids accommodated in chambers. The analytical magazine is arranged to be accommodated in at least two orientations in an analytical system. The analytical magazine is furthermore arranged to provide the analytical system, in the orientations, in each case with a plurality of analytical aids. At least one sampling movement can be executed by means of the analytical aids. The analytical magazine is arranged to make a remagazining of the analytical aids possible. | 01-28-2016 |
20160029957 | HEALTH DIAGNOSTIC SYSTEMS AND METHODS - A health monitoring system, and methods of use and manufacture thereof are disclosed. The health monitoring system may include a computing system and a diagnostic test coupled to a diaper. The diagnostic test may include one or more sensors configured to produce a visual indication of one or more analytes contained in a sample produced by a subject. The diagnostic test may include a machine-readable code. The computing system may be configured to read the machine-readable code to allow an application running on the computing system to automatically perform at least one task related to a production of a data point based on the visual indication. The health monitoring system may aid in identifying a potential abnormal health condition of the subject by providing automatic longitudinal analysis of analytes contained in samples produced by the subject over a period of time. | 02-04-2016 |
20160038180 | Medical Applicator - A medical applicator and a manipulation unit for use in connection with specific variants of the medical applicator are disclosed. In general, the medical applicator has an insertion needle ( | 02-11-2016 |
20160045147 | Temperature Insensitive In Vivo Analyte Devices, Methods and Systems - Disclosed herein are membrane structures for use in analyte sensors, where the membrane structures exhibit low temperature sensitivity. | 02-18-2016 |
20160058316 | STRONG, CONDUCTIVE CARBON NANOTUBE ELECTRODES - In some embodiments, the present disclosure pertains to a device comprising at least one implantable microelectrode. In some embodiments, the implantable microelectrode comprises at least one fiber of aligned carbon nanotubes partially coated with a layer of biocompatible insulating material. In some embodiment of the present disclosure, at least one end of the fiber of aligned carbon nanotubes is uncoated. In some embodiments, the uncoated end of the fiber is electrically active. In some embodiments, the device further comprises a removable inserting device attached to the implantable microelectrode. In some embodiments, the present disclosure pertains to a method of implanting an implantable microelectrode into a subject. In some embodiments, the present disclosure relates to a method of fabricating an implantable microelectrode. | 03-03-2016 |
20160073941 | ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors. | 03-17-2016 |
20160100852 | Systems and Devices for Cutting Tissue - Systems and devices are described which include a tissue cutting device including a central rotatable shaft having a first end and a second end; a motor operably coupled to the first end of the central rotatable shaft, the motor including circuitry configured to rotate the central rotatable shaft; a moveable component configured to move along at least a portion of the length of the central rotatable shaft; and an elongated flexible cutting component having a first end and a second end, the first end of the elongated flexible cutting component secured to the moveable component and the second end of the elongated flexible cutting component secured to the central rotatable shaft in proximity to the second end of the central rotatable shaft; wherein movement of the moveable component along the at least a portion of the length of the central rotatable shaft changes a shape formed by the elongated flexible cutting component. | 04-14-2016 |
20160100853 | Systems and Devices for Cutting Tissue - Systems and devices are described which include a tissue cutting device including a tethering component; an elongated flexible cutting component having a first end and a second end, the first and the second end of the elongated flexible cutting component secured to the tethering component; at least one tether having a first end and a second end, the first end of the at least one tether attached to the elongated flexible cutting component, the second end of the at least one tether operably coupled to the tethering component, the tethering component configured to at least one of extend and retract the at least one tether; and a motor operably coupled to the tethering component, the motor including circuitry configured to rotate the tethering component and the secured elongated flexible cutting component; wherein extension and retraction of the at least one tether by the tethering component changes a shape formed by the elongated flexible cutting component. | 04-14-2016 |
20160100854 | Systems and Devices for Cutting Tissue - Systems and devices are described which include a tissue cutting device including a central rotatable shaft having a first end and a second end; a motor operably coupled to the first end of the central rotatable shaft, the motor including circuitry configured to rotate the central rotatable shaft; a tethering component; and an elongated flexible cutting component having a first end and a second end, the first end of the elongated flexible cutting component secured to the central rotatable shaft at a position between the first end and the second end central rotatable shaft, the second end of the elongated flexible cutting component operably coupled to the tethering component, the tethering component configured to at least one of extend and retract the elongated flexible cutting component; wherein extension and retraction of the elongated flexible cutting component by the tethering component changes a shape formed by the elongated flexible cutting component. | 04-14-2016 |
20160124063 | Magnetic Relaxometry to Assess Disease via Circulating Markers - Methods and apparatuses for detecting substances circulating in a patient's blood are described. The substances, such as tumor cells, are targeted with nanoparticles labeled such that they preferentially bind with the substance of interest. As the nanoparticle-labeled substance circulates, it can pass near a magnetic relaxometry system that can detect the substance by detecting the nanoparticles bound to it. | 05-05-2016 |
20160128572 | ACOUSTIC COMPUTING SYSTEMS FOR IMPLANT AND DERMAL DATA COMMUNICATION, POWER SUPPLY AND ENERGY STORAGE - Embodiments are directed to a computing system that operates at least partially through a medium, which may be a human. The computing system includes a first acoustic computing element implanted in the human. The first acoustic computing element receives input acoustic vibration. The first acoustic computing element converts a first portion of the input acoustic vibration to energy that powers an operation of the first acoustic computing element. The first acoustic computing element converts a second portion of the input acoustic vibration to stored energy of the first acoustic computing element. The first acoustic computing element converts a third portion of the input acoustic vibration to a first input data that is processed by the first acoustic computing element. The first acoustic computing element generates and transmits a first output acoustic vibration based on the first input data. | 05-12-2016 |
20160151006 | Analyte Sensor Calibration Management | 06-02-2016 |
20160157758 | ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors. | 06-09-2016 |
20160174881 | ON-BODY MEDICAL DEVICE SECUREMENT | 06-23-2016 |
20160183819 | SENSING FOLEY CATHETER - Sensing Foley catheter variations are described herein which may comprise a fluid chamber defining a receiving channel and a port fluidly coupled to a drainage lumen of the catheter such that the receiving channel is in fluid communication with the drainage opening. A pressure sensing mechanism located within the fluid chamber may comprise a pressure sensing mechanism which is configured to detect fluid pressure when body fluid, such as urine, is introduced into the drainage opening of the catheter and is received within the receiving channel and impinges upon the pressure sensing mechanism. | 06-30-2016 |
20160192870 | ANALYTICAL AIDS WITH HYDROPHILIC COATING CONTAINING NANOPARTICLES WITH SILICA STRUCTURE AND METHODS OF PRODUCING AND USING THE SAME | 07-07-2016 |
20160192880 | Intra-Oral Detector and System for Modification of Undesired Behaviors and Methods Thereof | 07-07-2016 |
20160198984 | Nanocellulose and Nanocellulose Composites as Substrates for Conformal Bioelectronics | 07-14-2016 |
20160198989 | IMPLANTABLE DEVICES AND METHODS FOR THE EVALUATION OF ACTIVE AGENTS | 07-14-2016 |
20160374597 | SYSTEMS AND METHODS FOR NORMALIZATION OF CHEMICAL SENSOR DATA BASED ON FLUID STATE CHANGES - Embodiments herein include implantable medical systems, devices and methods including chemical sensors. In an embodiment, an implantable medical device system includes a chemical sensor; a fluid state sensor such as a posture sensor; an activity sensor; and/or a respiration sensor. The implantable medical device system can further include normalization circuitry receiving data from the chemical sensor and the fluid state sensor and normalizing the chemical sensor data based on data from the fluid state sensor. In an embodiment, a method of operating an implantable medical device system is included. The method can include measuring the amount of a chemical analyte using a chemical sensor, measuring the fluid status in a patient using a fluid state sensor, and normalizing the measured amount of the chemical analyte as indicated by the chemical sensor using normalization circuitry based on data from the fluid state sensor. Other embodiments are also included herein. | 12-29-2016 |
20160374598 | SMART SWEAT STIMULATION AND SENSING DEVICES - The disclosed invention provides sweat sensing devices with smart sweat stimulation and sensing embodiments: which improve the dependability and predictability of sweat sampling rates; achieve a desired number of sweat sampling events per day while minimizing skin irritation and prolonging device lifespan; and use physical, optical or thermal sweat stimulation to augment or replace chemical sweat stimulation. | 12-29-2016 |
20190142311 | CALIBRATION FOR EAB BIOFLUID SENSORS | 05-16-2019 |
20190142345 | ANALYTE MONITORING SYSTEM AND METHOD FOR DETERMINING SYSTEM USAGE | 05-16-2019 |
20220133178 | FIBROUS COVER LAYER FOR MEDICAL DEVICES - Embodiments herein relate to implantable medical devices including a fibrous cover layer. In an embodiment, an implantable medical device is included having a housing, an optical chemical sensing element disposed along the housing, and a fibrous electrospun cover layer, wherein the fibrous electrospun cover layer is disposed over the optical chemical sensing element. In another embodiment, a method of making an implantable medical device is included. The method can specifically include depositing an optical chemical sensing element into a sensor optical carrier attached to a housing and applying a fibrous electrospun cover layer over the optical chemical sensing element. Other embodiments are also included herein. | 05-05-2022 |
20220133181 | SYSTEMS, DEVICES, AND METHODS FOR DETECTING EARLY SHOCK - Systems, devices, and methods to measure interstitial concentration of selected compounds over time to provide early detection of shock are described. In an example method, interstitial fluid is obtained from a subject. Analytes are detected in the interstitial fluid. At least one of the analytes corresponds to hypoxia of a tissue of the subject and at least one other analyte corresponds to vascular permeability of the subject. The example method further includes determining whether the subject is in shock based on a computing model and the detected analytes and generating an alert based on whether the subject is in shock. Treatments can be administered following the alert generation. | 05-05-2022 |