Class / Patent application number | Description | Number of patent applications / Date published |
546275400 | 1,2-diazoles (including hydrogenated) | 60 |
20080242865 | PROCESSES FOR THE PREPARATION OF HYDROXYLAMINES - The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia): | 10-02-2008 |
20090036686 | PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3-PYRAZOLIDINECARBOXYLATES - A method is disclosed for preparing a 2-substituted-5-oxo-3-pyrazolidinecarboxylate compound of Formula I | 02-05-2009 |
20090093637 | Synthesis of 1,3,4-Trisubstituted and 1,3,4,5-Tetrasubstituted Pyrazoles - This invention concerns the synthesis of highly substituted pyrazoles, which are structural components of pharmacological compounds, through reaction of hydrazones with nitroolefins. | 04-09-2009 |
20090240058 | Activator for Peroxisome Proliferator-Activating Receptor Delta - A compound or its salt having the following formula (II) is used as an activator for PPAR δ: | 09-24-2009 |
20100022780 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with at least one compound of Formula 3 in the presence of a solvent comprising one or more organic solvents selected from ethers and nitrites and a catalytically effective amount of a palladium complex comprising at least one tertiary phosphine ligand of Formula 4 | 01-28-2010 |
20100029950 | NOVEL SUBSTITUTED 1H-DIHYDROPYRAZOLES, THEIR PREPARATION AND USE - This invention provides compounds of Formula I, methods for their preparation and use for preparing compounds of Formula II | 02-04-2010 |
20100063293 | PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND - To provide a process for producing a specific anthranilamide compound or its salt. | 03-11-2010 |
20100113794 | METHOD FOR PRODUCING AMIDE COMPOUND - Disclosed is a method for producing an amide compound represented by the formula (3) below and having an excellent control activity against a harmful arthropod, which is characterized in that an aniline compound represented by the formula (1) below and an aldehyde compound represented by the formula (2) below are reacted in a solvent in the presence of an oxidizing agent such as oxygen or a peroxide. (In the formulae below, R | 05-06-2010 |
20100145059 | METHOD FOR PRODUCING HYDRAZINE COMPOUND,AND PRODUCTION INTERMEDIATES OF HYDRAZINE COMPOUND AND METHODS OF PRODUCING THE INTERMEDIATES - Provided are a novel method for producing a hydrazine compound useful as an insecticidal compound, and production intermediates which can be suitably used for the production method and methods for producing the intermediates. As the production intermediates, a specific isocyanate compound and an organomagnesium compound represented by the following general formula (IV) are provided. The organomagnesium compound can be synthesized from a corresponding dibromo compound. | 06-10-2010 |
20100317864 | Preparation Method of Phenylcarboxamides - A preparation method of phenylcarboxamides of formula (I), the reaction scheme of which is as follows: | 12-16-2010 |
20110003998 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 | 01-06-2011 |
20110021782 | Novel alkoxy enones and enamino ketones and a process for preparation thereof - The present invention relates to novel alkoxy enones and enamino ketones, and to a novel process for preparation thereof. Alkoxy enones and enamino ketones are valuable intermediates for preparation of pyrazoles and anthranilamides, which can be used as insecticides. | 01-27-2011 |
20110028729 | Process for preparing aryl-substituted pyrazoles - The present invention relates to a process for preparing 1-aryl-substituted pyrazoles, comprising the reaction of alkoxy enones and enamino ketones with arylhydrazine derivatives to give 1-aryl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-aryl-substituted trihalomethylpyrazoles, and the further processing thereof. | 02-03-2011 |
20110034695 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with at least one alkali metal cyanide of Formula 3 and a compound of Formula 4. | 02-10-2011 |
20110034696 | PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND - To provide a process for producing an anthranilamide having the 3-position of pyrazole substituted by a bromine atom, or its salt. | 02-10-2011 |
20110087029 | Process for Preparing Pyridyl-Substituted Pyrazoles - The present invention relates to a process for preparing 1-pyridyl-substituted pyrazoles, comprising the reaction of acetyleneketones with pyridylhydrazine derivatives to give 1-pyridyl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-pyridyl-substituted trihalomethylpyrazoles, and the further processing thereof. | 04-14-2011 |
20110152531 | Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation - The present invention relates to novel acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes of the general formula (I) | 06-23-2011 |
20110160459 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS - The invention is directed to 5-(hetero)aryl-4,5-dihydro-(1H)-pyrazole (pyrazoline) derivatives as cannabinoid CB | 06-30-2011 |
20110184183 | METHOD FOR PREPARING A NON-HYDRATABLE CRYSTAL FORM - A method is disclosed for preparing a non-hydratable crystal form from a hydratable crystal form of 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)-carbonyl]phenyl]-1H-pyrazole-5-carboxamide (Compound 1). | 07-28-2011 |
20110237801 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING THESE, METHOD OF PRODUCTION AND USE - The disclosure relates to a compound of formula (I): | 09-29-2011 |
20130012715 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES - The invention describes a novel process for synthesizing pyrazoles by means of oxidative conversion of enamines with suitable N-containing carboxylic acid derivatives. | 01-10-2013 |
20130131347 | Process for Preparing Pyridyl-Substituted Pyrazoles - The present invention relates to a process for preparing 1-pyridyl-substituted pyrazoles, comprising the reaction of acetyleneketones with pyridylhydrazine derivatives to give 1-pyridyl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-pyridyl-substituted trihalomethylpyrazoles, and the further processing thereof. | 05-23-2013 |
20130131348 | PROCESS FOR PRODUCING AMIDE COMPOUND - There is provided a process for producing an amide compound having an excellent harmful arthropod-controlling activity and represented by the formula (3): | 05-23-2013 |
20130131349 | PROCESS FOR PRODUCING AMIDE COMPOUND - There is provided a process for producing an amide compound having an excellent harmful arthropod-controlling activity and represented by the formula (3): | 05-23-2013 |
20130190503 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR FIBROMYALGIA - A therapeutic agent or prophylactic agent has an analgesic effect on both nociceptive pain and neuropathic pain and is effective in treatment of fibromyalgia. The agent includes as an effective ingredient a cyclohexane derivative or a pharmaceutically acceptable salt thereof or a prodrug thereof. | 07-25-2013 |
20130310567 | METHOD FOR PREPARING 2-AMINOBENZAMIDE DERIVATIVES - A method for preparing a compound of Formula 1 comprising contacting a compound of Formulae 2 and 3 in the presence of a palladium source, a ligand, a base and carbon monoxide | 11-21-2013 |
20140235865 | METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING PYRAZOLIC ACIDS WITH ANTHRANILIC ACID ESTERS - The present invention relates to a process for preparing tetrazole-substituted anthranilic acid diamide derivatives of the formula (1) | 08-21-2014 |
20150011772 | METHOD FOR PRODUCING SUBSTITUTED ANTHRANILIC ACID DERIVATIVES - The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) | 01-08-2015 |
20150087843 | Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof - The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carboxylate compound of the formula (I-A) | 03-26-2015 |
20150112073 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 04-23-2015 |
20150112074 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 04-23-2015 |
20150112075 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 04-23-2015 |
20150112076 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 04-23-2015 |
20150322037 | POLYSUBSTITUTED PYRIDYL PYRAZOLECARBOXAMIDE AND PREPARATION METHOD AND USE THEREOF - The present invention discloses a polysubstituted pyridyl pyrazolecarboxamide and its preparation method and use. The structure of the polysubstituted pyridyl pyrazolecarboxamide of the present invention is shown in the following General Formula I. The polysubstituted pyridyl pyrazolecarboxamide has the following advantages such as good insecticidal effect, low production cost; and it may be used in control of agriculture, forest or health pests, especially of resistant pests. For its preparation method, the yield is high, the number of steps is small, and the operation is simple. | 11-12-2015 |
20150336929 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 11-26-2015 |
20160031848 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE - 3-(3-Chloro-1H-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-•dihydrochloride with commercially available 3-ethoxyacrylonitrile to provide 3-(3-amino-1H-pyrazol-1-yl)pyridine, and by converting the amino group to a chloro group by a Sandmeyer reaction. | 02-04-2016 |
20160031849 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE - 3-(3-Chloro-1H-pyrazol-1-yl)pyridine is prepared by coupling 3-bromopyridine with commercially available 3-aminopyrazole, purifying the 3-(3-amino-1H-pyrazol-1-yl)pyridine by crystallization, and converting the amino group to a chloro group by a Sandmeyer reaction. | 02-04-2016 |
20160031850 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE - 3-(3-Chloro-1H-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-dihydrochloride with acrylonitrile to provide 1-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-amine, by oxidizing to provide 3-(3-amino-1H-pyrazol-1-yl)pyridine, and by converting the amino group to a chloro group by a Sandmeyer reaction. | 02-04-2016 |
20160046572 | Process for Preparing Sulfimines and Their in-situ Conversion into N-(1-Amino-Benzoyl)-Sulfimines - The present invention relates to a process for preparing a compound of the formulae (Ia) or (Ib), or a mixture thereof, | 02-18-2016 |
20160046607 | METHOD FOR PRODUCING SUBSTITUTED ANTHRANILIC ACID DERIVATIVES - The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) | 02-18-2016 |
20160096819 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF - The present invention relates to a process for preparing N-substituted 1H-pyrazole-5-carboxylic acid compounds of the formula I-A and derivatives thereof, in particular the corresponding carbonylchloride compounds (acid chlorides). It also relates to the use of these acid chlorides for preparing anthranilamide derivatives that are useful pesticides. in which the variables are as defined in the claims and the specification comprising the steps of i) reacting a compound of the formula (II) with a base selected from combinations of a magnesium-organic compound having a carbon bound magnesium and a secondary amine and magnesium amides of secondary amines in the presence of a lithium halide, where the base is used in an amount sufficient to achieve at least 80% deprotonation of the compound of formula (II); and subjecting the product obtained in step (i) to a carboxylation by reacting it with carbon dioxide or a carbon dioxide equivalent, to obtain a magnesium salt of the compound of formula (I-A) and optionally aqueous workup to obtain the compound of the formula (I-A) as a free acid. | 04-07-2016 |
20160137625 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 05-19-2016 |
20160152593 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | 06-02-2016 |
546275700 | Polycyclo ring system having the 1,2-diazole ring as one of the cyclos | 5 |
20080242866 | SYNTHESIS OF ANTHRANILAMIDES - The present invention relates to a novel method of preparing anthranilamides of formula I: | 10-02-2008 |
20090131675 | Methods for structural analysis of proteins - The invention provides methods and compositions for protein structure analysis, including substrate binding sites, sites of protein-protein interactions, three dimensional structure analysis, and stability, all with single amino acid resolution. In general, the subject methods involve introduction of cysteine residues, which serve as probes for physical analysis, into a protein by translational misincorporation in vivo. In many embodiments, proteins containing misincorporated cysteine residues are reacted with a crosslinking agent that covalently links misincorporated cysteine residues to a proximal amino acid in the folded protein. These methods, termed “MXLINK” methods, may be used for protein tertiary structure analysis. In other embodiments, cysteine-misincorporated proteins are used in protein footprinting methods, termed “MPAX” or “MSX” methods. | 05-21-2009 |
20100179329 | CRYSTALLINE FORMS OF 6-[2-(METHYLCARBAMOYL)PHENYLSULFANYL]-3-E-[2-(PYRIDIN-2-YL)ETHENYL]INDAZO- LE SUITABLE FOR THE TREATMENT OF ABNORMAL CELL GROWTH IN MAMMALS - The present invention relates to crystalline polymorphic and amorphous form of 6-[2-(methylcarbamoyl)phenyl sulfanyl]-3-E-[2-(pyridin-2-yl)ethenyl]indazole and to methods for their preparation. The invention is also directed to pharmaceutical compositions containing at least one polymorphic form and to the therapeutic or prophylactic use of such polymorphic forms and compositions. | 07-15-2010 |
20130102787 | NOVEL INDAZOLE DERIVATIVE OR SALT THEREOF AND PRODUCTION INTERMEDIATE THEREOF, AND ANTIOXIDANT USING SAME, AND USE OF INDAZOLE DERIVATIVE OR SALT THEREOF - A compound represented by formula (1) or salt thereof and a production intermediate thereof are created. The compound exhibited an excellent antioxidation action in a microsome lipid peroxidation measuring system using a rat liver microsome. Therefore, the compound or salt thereof is useful as an antioxidant. The present invention also provides use of a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof for production of an antioxidant. | 04-25-2013 |
20190144420 | SYNTHESIS OF INDAZOLES | 05-16-2019 |
546276100 | Chalcogen attached directly to the 1,2-diazole ring by nonionic bonding | 12 |
20090131676 | PYRAZOLE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS - A compound represented by the formula (I) (wherein R | 05-21-2009 |
20100222592 | Pyridone Derivative and Herbicide - A pyridone derivative represented by Formula [1] or an agriculturally acceptable salt thereof: | 09-02-2010 |
20100280251 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 | 11-04-2010 |
20110124871 | ARTHROPODICIDAL ANTHRANILAMIDES - This invention provides compounds of Formula 1, their N-oxides and agriculturally suitable salts | 05-26-2011 |
20110152532 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives - The present invention relates to a process for the preparation of 1-alkyl- or 1-aryl-substituted 5-pyrazolecarboxylic acid derivatives comprising the reaction of substituted 1,3-dioxolanes and 1,4-dioxanes with alkyl- or arylhydrazines to give 1-alkyl- or 1-aryl-substituted dihydro-1H-pyrazoles, and their further reaction to give 1-alkyl- or 1-aryl-substituted 5-pyrazolecarboxylic acid derivatives, which can be used as valuable intermediates for producing insecticidally effective anthranilamides. | 06-23-2011 |
20120130080 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 | 05-24-2012 |
20130018192 | Aryl-substituted Pyrazoles - The present invention relates to a process for preparing 1-aryl-substituted pyrazoles, comprising the reaction of alkoxy enones and enamino ketones with arylhydrazine derivatives to give 1-aryl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-aryl-substituted trihalomethylpyrazoles, and the further processing thereof. | 01-17-2013 |
20150112077 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 04-23-2015 |
20150112078 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS - The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds. | 04-23-2015 |
20160052908 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE - 3-(3-chloro-1H-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-.dihydrochloride with a dialkyl maleate to provide an alkyl 5-oxo-2-(pyridin-3-yl)pyrazolidine-3-carboxylate, by chlorinating to provide an alkyl 3-chloro-1-(pyridin-3-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate, by oxidizing to provide an alkyl 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-5-carboxylate, by converting the ester to the carboxylic acid by hydrolysis to provide 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-5-carboxylic acid hydrochloride, and by removing the carboxylic acid by a decarboxylation reaction. | 02-25-2016 |
20160075681 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE - This disclosure relates to the field of preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine and intermediates therefrom. These intermediates are useful in the preparation of certain pesticides. | 03-17-2016 |
20160137624 | PROCESS FOR PREPARING PYRIDYLPYRAZOLE COMPOUNDS AND DERIVATIVES THEREOF FROM PYRIDYLHYDRAZINE - The present invention relates to a process for preparing pyridylpyrazole compounds of the formula (I) | 05-19-2016 |