Class / Patent application number | Description | Number of patent applications / Date published |
514655000 | The aryl ring or aryl ring system and amino nitrogen are bonded directly to the same acylic carbon, which carbon additionally has only hydrogen or acyclic hydrocarbyl substituents bonded directly thereto | 29 |
20080262096 | Squaric Acid Derivatives - Novel squaric acid compounds of the formula (I), in which R, R | 10-23-2008 |
20080319087 | Use of Ambroxol for the Treatment of Rhinovirus Infections - The invention is directed to the use of ambroxol or pharmaceutically acceptable salts thereof for preparing a medical composition for treating or preventing infections caused by human rhinovirus. Surprisingly it was found that Ambroxol is capable to suppress the replication of human rhinovirus. Therefore, the ambroxol-containing medical composition is suitable to treat or prevent against all symptoms of a rhinovirus infection and provides a direct antivirale effect. | 12-25-2008 |
20090069441 | Motuporamine Mimic Agents - Disclosed herein are motuporamine mimic agents and methods of making and using same. Particularly exemplified are motuporamine mimic agents comprising cytotoxic activity and/or anti-metaplastic activity. | 03-12-2009 |
20090082469 | DEUTERIUM-ENRICHED TERBINAFINE - The present application describes deuterium-enriched terbinafine, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-26-2009 |
20090099266 | Antifungal nail coat and method of use - Antifungal nail coat compositions containing an allylamine, an N,N-di(C | 04-16-2009 |
20090197970 | CRYSTALLINE FORM OF CINACALCET - The present invention relates to the polymorph form II of Cinacalcet hydrochloride, methods for the preparation of pure form II of Cinacalcet hydrochloride, and pharmaceutical compositions comprising the new polymorphic form in an pharmaceutically effective amount The present invention also provides novel solvates of Cinacalcet hydrochloride, methods for the preparation of these solvates, the use of these novel solvates for the preparation of pure Cinacalcet hydrochloride, the use of these novel solvates for the preparation of polymorphic form II of Cinacalcet hydrochloride and pharmaceutical compositions comprising the acetic acid solvate of Cinacalcet hydrochloride. | 08-06-2009 |
20100048724 | Subunguicide, and Method for Treating Onychomycosis - Onychomycosis is a fungal infection of the nail bed and is difficult to treat topically because penetration of the nail plate is difficult, and systemic antifungal treatments are prone to side effects and drug interactions. The present invention treats onychomycosis by applying an antifungal composition to the nail bed directly using a solid, semi-solid, or flowable carrier. The carrier can be in the form of a semi-solid into which the user digs and scrapes the nail, a solid carrier can be inserted directly under the nail in contact with the nail bed, or a flowable composition can be injected in contact with the nail bed. | 02-25-2010 |
20100087545 | PURIFICATION PROCESS - Process for the preparation of pure allylamine pharmaceutical terbinafine of formula I | 04-08-2010 |
20100113607 | Pharmaceutical Compositions - A method for the topical treatment of nail diseases, e.g. onychomycosis, after preparation of the infected nail with a laser beam. | 05-06-2010 |
20100168247 | SOLID COMPOSITES OF A CALCIUM RECEPTOR-ACTIVE COMPOUND - The invention encompasses solid composites of the calcium receptor-active compounds, processes for preparing the solid composites, immediate and controlled-release pharmaceutical formulations comprising the solid composites, and methods of treatment therewith. | 07-01-2010 |
20120302644 | ADHESIVE PATCH FOR TREATMENT OF TINEA UNGUIUM - The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm | 11-29-2012 |
20120309843 | HIGHLY PERMEATING TERBINAFINE FORMULATION - The present invention provides topical compositions, methods of preparation, and methods of treatment for onychomychosis. In certain specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a zwitterionic surfactant or charged derivative thereof; a carboxylic acid, a lower alcohol, and water. The acid is selected from a short-chain hydroxy acid, a short-chain fatty acid, and a mixture thereof. In certain other specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a quarternary amino acid, a keratolytic agent; a lower alcohol; and water. In certain embodiments, the keratolytic agent is urea, ammonium thioglycolate, or a mixture thereof. | 12-06-2012 |
20130090388 | METHOD OF TREATING GAUCHER DISEASE - Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof. | 04-11-2013 |
20130184352 | METHOD OF TREATING GAUCHER DISEASE - Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof. | 07-18-2013 |
20130210925 | SUBUNGUICIDE, AND METHOD FOR TREATING ONYCHOMYCOSIS - Onychomycosis is a fungal infection of the nail bed and is difficult to treat topically because penetration of the nail plate is difficult, and systemic antifungal treatments are prone to side effects and drug interactions. The present invention treats onychomycosis by applying an antifungal composition to the nail bed directly using a solid, semi-solid, or flowable carrier. The carrier can be in the form of a semi-solid into which the user digs and scrapes the nail, a solid carrier can be inserted directly under the nail in contact with the nail bed, or a flowable composition can be injected in contact with the nail bed. | 08-15-2013 |
20130267605 | AQUEOUS COMPOSITION COMPRISING BROMHEXINE - The present invention relates to aqueous compositions containing bromhexine, the composition comprising an amount of sugar alcohols of less than 10 g based on 100 ml of the composition, and the use thereof for secretolytic therapy in acute and chronic bronchopulmonary disorders. | 10-10-2013 |
20130274342 | COMPOSITIONS AND METHODS FOR TREATING COUGH - Compositions, methods of making compositions and methods of treating cough are described herein. In some embodiments, the compositions are lozenges comprising memantine and an alkalinizing agent. | 10-17-2013 |
20140031430 | NOVEL ANTIFUNGAL COMPOSITION - There is provided a pharmaceutical composition for the treatment of fungal infection of the nail comprising a anti-fungal allylamine compound present in an amount of about 10%, an organic acid or an ester thereof, a diol and a sequestering agent where the pharmacological composition is essentially water-free | 01-30-2014 |
20140057989 | POLYAMINE TRANSPORTER SELECTIVE COMPOUNDS AS ANTI CANCER AGENTS - Several aromatic hydrocarbons di-substituted with a polyamine are described according to formulas selected from compounds 4, 7, 10, 15 and pharmaceutically acceptable salts thereof. The novel dimeric polyamines of the present invention demonstrate enhanced penetration into cells having an upregulated polyamine transport system, such as various types of cancer cells. The disclosed aromatic polyamine dimers provide highly efficient drugs for targeting cancer cells with active polyamine transporters. | 02-27-2014 |
20140066518 | USE OF A SPRAYABLE COMPOSITION COMPRISING AMBROXOL - The present invention relates to ambroxol hydrochloride for the treatment of acute pharyngitis, wherein ambroxol hydrochloride as a sprayable composition comprising up to 30 mg/ml ambroxol hydrochloride is administered locally in a dose of 1 to 20 mg. | 03-06-2014 |
20140094523 | SOLID AMBROXOL-CONTAINING PREPARATION - The present invention relates to solid preparations containing ambroxol which are obtainable by melt extrusion of the mixture consisting of a) 30 to 80% by weight of ambroxol hydrochloride, b) 2 to 68% by weight of at least one hydrogenated vegetable oil, c) 2 to 68% by weight of at least one mixture containing fatty acid ester and/or hydroxy fatty acid ester and d) 0 to 66% by weight of one or more pharmaceutical adjuvants, based in each case on the total amount of the preparation and its use for secretolytic treatment in acute and chronic bronchopulmonary diseases. | 04-03-2014 |
20140235729 | BENZYLAMINE CONTAINING COMPOSITIONS AND METHODS FOR APPETITE SUPPRESSION - Herbal compositions and techniques for suppressing appetite and managing weight are described. These compositions and techniques are based at least in part on beneficial results showing that benzylamine can suppress appetite. In at least one embodiment, a composition that includes an effective amount of benzylamine and an effective amount of at least one benzylamine enhancer may be utilized for appetite suppression. | 08-21-2014 |
20140249233 | METHOD FOR ENHANCING FOLDING AND TRANSPORT OF MISFOLDED GLUCOCEREBROSIDASE - Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof. | 09-04-2014 |
20140296347 | METHOD OF TREATING ONYCHOMYCOSIS - The present invention is directed to a nail lacquer consisting essentially of terbinafine as an antimycotic agent, hydroxypropyl chitosan as film forming agent, water and a lower alkanol as solvents. The invention is also directed to a method for treating onychomycosis by topically administering such a nail lacquer to a patient in need of such a treatment. | 10-02-2014 |
20150111971 | TOPICAL PHARMACEUTICAL COMPOSITIONS - The present invention relates to a topical pharmaceutical composition comprising, based on the total weight of the composition:
| 04-23-2015 |
20150306049 | IMMEDIATE RELEASE FORMULATIONS OF CINACALCET - The invention relates to pharmaceutical compositions comprising:
| 10-29-2015 |
20150342871 | HIGHLY PERMEATING TERBINAFINE FORMULATION - The present invention provides topical compositions, methods of preparation, and methods of treatment for onychomycosis. In certain specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a zwitterionic surfactant or charged derivative thereof; a carboxylic acid, a lower alcohol, and water. The acid is selected from a short-chain hydroxy acid, a short-chain fatty acid, and a mixture thereof. In certain other specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a quarternary amino acid, a keratolytic agent; a lower alcohol; and water. In certain embodiments, the keratolytic agent is urea, ammonium thioglycolate, or a mixture thereof. | 12-03-2015 |
20160075633 | Polyamine Transporter Selective Compounds as Anti-Cancer Agents - Several aromatic hydrocarbons di-substituted with a polyamine are described according to formulas selected from compounds 4, 7, 10, 15 and pharmaceutically acceptable salts thereof. The novel dimeric polyamines of the present invention demonstrate enhanced penetration into cells having an upregulated polyamine transport system, such as various types of cancer cells. The disclosed aromatic polyamine dimers provide highly efficient drugs for targeting cancer cells with active polyamine transporters. | 03-17-2016 |
20160113892 | Method For Enhancing Folding and Transport of Misfolded Glucocerebrosidase - Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof. | 04-28-2016 |