Class / Patent application number | Description | Number of patent applications / Date published |
073610580 | Detector detail | 12 |
20080271520 | LIQUID CHROMATOGRAPHIC ANALYZER AND LIQUID CHROMATOGRAPHY ANALYSIS - An apparatus for liquid chromatography which detects ingredients by an electrolytic device, wherein the apparatus can detect many kinds of substances in high sensitivity by making possible to apply a wider range of electrolyzing voltage than former apparatus. | 11-06-2008 |
20080276694 | Analytical Methods For 2-Deoxy-D-Glucose - 2-Deoxy-2-D-glucose (2-DG) concentration and purity can be measured in a sample of crystalline or liquid by HPLC with accuracy and precision suitable for analysis of active pharmaceutical ingredient and drug product. | 11-13-2008 |
20110100100 | Fluid Separation Conduit Cartridge - A fluid separation conduit cartridge comprising a fluid separation conduit is disclosed. In certain embodiments the fluid separation conduit is potted to provide operation at increased pressures. In other embodiments, the fluid separation conduit cartridge has one or more memory units. The memory units are operative to store data such as, for example, cartridge usage and test results. | 05-05-2011 |
20130091936 | ELECTROCHEMICAL DETECTION CELL FOR LIQUID CHROMATOGRAPHY SYSTEM - A detection cell for a chromatography system includes a cell body having an inlet, an outlet, and a counter electrode, a working electrode, a sample flow passageway extending between the inlet and the outlet and in fluid contact with the counter and working electrodes, and a palladium/noble metal reference electrode system. A method of using the detection cell is also described. | 04-18-2013 |
20140047908 | High-throughput multi laser wave mixing methods and apparatus - This invention relates to methods and apparatus of a combination of laser wave mixing technology with diagnostic flow technologies with embodiments describing supercritical fluid chromatography. The combination of these technologies along with minute detection levels have not yet been seen in the field. | 02-20-2014 |
20140250984 | PULSED ION MULTIFUNCTIONAL DETECTOR FOR BOTH HIGH PERFORMANCE LIQUID CHROMATOGRAPH AND ION CHROMATOGRAPH - A pulsed ion multifunctional detector used for both high performance liquid chromatograph and ion chromatograph, and experiment chromatograms attached also show that the detector has excellent multipurpose function in liquid chromatograph. The casing of the instrument is provided with a sample solution inlet, a sample solution outlet, a power supply socket, a liquid crystal display, an operation keyboard and a detection signal output interface. In the casing is provided a detection electromechanical member, which includes a central controller, a detection cell, a preposed subtracting module, a polarity transformation module, a noise processing module and an output amplifier module. The pulsed ion multifunctional detector can sensitively and accurately measure ion current of sample ionized directly in the detection cell, and subtract baseline background generated by various mobile phases and automatically eliminate dynamic noise and drift of the instrument. | 09-11-2014 |
20140338432 | METHODS OF SEPARATING LIPIDS - The invention provides novel, simple, reliable and effective methods for separating various lipids from biological samples. In certain embodiments, the invention provides HILIC-based UHPLC separation methods. In one embodiment, the methods of the invention offer an efficient and rapid separation of ether glycophospholipids (e.g., plasmalogens) from their diacyl or monoacyl counterparts within the same lipid class. In certain instances, the invention relates to the use of a Waters ACQUITY UPLCĀ® system. | 11-20-2014 |
20150090014 | DETECTOR FOR LIQUID CHROMATOGRAPHY - A detector for liquid chromatography has light sources that generate light in an ultraviolet region and in a near-infrared region; a flow cell, through which sample liquid flows; an optical system to let light generated from the light sources become incident on the flow cell concurrently; a detection element that detects light in the ultraviolet region that passes through the flow cell; a detection element that detects light in the near-infrared region that passes through the flow cell; and an arithmetic operation part that performs arithmetic operation of a first signal value obtained from the detection element and of a second signal value obtained from the detection element. The arithmetic operation part combines the first signal value and the second signal value to calculate a signal value with a reduced baseline fluctuation resulting from a mobile phase during a gradient analysis. | 04-02-2015 |
20150143880 | HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH UV-VISIBLE DETECTION - Apparatus and methods for high performance liquid chromatography. The apparatus includes a preparation loop comprising two linear stepping pumps, a sample loop comprising a sample injector, a chromatography column, and a detector device. The detector device can include a flash lamp, a flow cell, and a light sensor comprising an entrance slit, a grating; and a charge-coupled device array. | 05-28-2015 |
20150298025 | FOCUSED SAMPLE DELIVERY AND ELUENT SELECTION FOR CHROMATOGRAPHY - The present invention is directed to a chromatography system which comprises a column extending between first and second ends and defining a passage containing a chromatographic sorbent for retaining and separating components of a sample. In one embodiment, there is an inlet fitting device proximate to the first end of the column to define a column inlet port, a sample conduit positioned to discharge a sample into the inlet fitting device, a mobile phase conduit separate from the sample conduit and positioned to discharge fluid into the inlet fitting device, a first fluid pump connected to the mobile phase conduit for conveying a mobile phase fluid into the mobile phase conduit, and a second fluid pump connected to the sample conduit for conveying a sample into the sample conduit. In another embodiment, there is a column inlet port proximate the first end of said column, an outlet fitting device proximate to the second end of the column defining a column outlet port, a first effluent conduit positioned to receive a material discharged from the outlet fitting device, and a second effluent conduit separate from the first conduit and positioned to receive material discharged from the outlet fitting device. A further embodiment of the present invention relates to a column inlet port proximate the first end of the column, a first frit proximate to the first end of the column, a second frit proximate to the second end of the column, where the first and second frits are positioned to retain the sorbent within the passage of the column, an outlet fitting device proximate to the second end of the column defining a column outlet port, and an effluent conduit positioned against the second frit to receive a material discharged from the outlet fitting device. Methods of analyzing with these systems are also disclosed. | 10-22-2015 |
20160033459 | QUANTITATION OF AMINES IN HYDROCARBONS - The present disclosure relates to methods for quantitation of amines in hydrocarbon stream. More specifically, the disclosure relates to rapid, precise and highly-sensitive methods for quantitating hydrogen sulfide-scavenging amines in crude petroleum oil or refinery streams. | 02-04-2016 |
20220137010 | METHODS OF DETERMINING PROTEIN STABILITY - The disclosure provides for a method of assessing stability of a therapeutic protein in a formulation comprising the steps of measuring thermal stability of the therapeutic protein wherein the value for thermal stability correlates with the main peak percent change determined by size exclusion chromatography in a statistically significant manner. | 05-05-2022 |