The California Institute for Biomedical Research Patent applications |
Patent application number | Title | Published |
20160115232 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF - Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response. | 04-28-2016 |
20160045514 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS - Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes. | 02-18-2016 |
20150238631 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF - Disclosed herein are switches for regulating the activity of a chimeric antigen receptor effector cells (CAR-ECs). The switches generally comprise a chimeric antigen receptor-interacting domain (CAR-ID) and a target interacting domain (TID). The switch may further comprise a linker. Further disclosed herein are methods of using the switches for the treatment of one or more conditions or diseases in a subject in need thereof. | 08-27-2015 |
20140271955 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS - Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes. | 09-18-2014 |