Rhodes Technologies Patent applications |
Patent application number | Title | Published |
20150038720 | Low-Temperature Synthesis of Methylphenidate Hydrochloride - The present invention describes a process for the preparation of methylphenidate hydrochloride. The process involves the esterification of ritalinic acid and methanol in the presence of an acid catalyst at a low temperature. The process may optionally involve the addition of an orthoester. | 02-05-2015 |
20140057932 | 1,3-Dioxanomorphides and 1,3-Dioxanocodides - The application is directed to compounds of Formula I | 02-27-2014 |
20130102784 | PROCESS FOR N-DEALKYLATION OF TERTIARY AMINES - The present disclosure provides improved methods for N-dealkylation of tertiary amines, including methods for N-demethylation of alkaloids and opioids, in which the dealkylation reaction is carried out in a solvent comprising a tertiary alcohol. The present disclosure also provides improved processes for preparing semi-synthetic opioids that incorporate the disclosed methods for N-dealkylation of tertiary amines. | 04-25-2013 |
20130102780 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 04-25-2013 |