RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK Patent applications |
Patent application number | Title | Published |
20130216637 | INDUCTION OF A PHYSIOLOGICAL DISPERSION RESPONSE IN BACTERIAL CELLS IN A BIOFILM - The present invention is directed to a compound which induces a physiological dispersion response in bacterial cells in a biofilm. The present invention is also directed to compositions containing this compound, methods of isolating the compound, and uses thereof. | 08-22-2013 |
20130183750 | ULTRA-SENSITIVE PORTABLE CAPILLARY SENSOR - A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its interior surface. The specific capture antibody is selected based upon a desired target analyte to be detected. A sample potentially containing the target antigen is introduced into the capillary tube. Thereafter, a second antibody labeled with a fluorescent dye is introduced. Upon excitation by electromagnetic energy, typically supplied by a laser, the fluorescence of the sample is captured and analyzed. The apparatus is extremely compact and rugged making it ideal for field use. In addition, accurate results may be obtained by relatively unskilled operators directly from a self-contained readout. Optionally, an external device (e.g., a computer) may be connected to the apparatus via an optional interface. The analysis time provided by the biosensor system of the invention is shorter than has heretofore been possible. | 07-18-2013 |
20130089876 | CAPILLARY BIOSENSOR SYSTEM AND ITS METHOD OF USE - A portable biosensor system includes at least one capillary tube extending longitudinally along a major axis between a proximal inlet end and a distal end. The at least one capillary tube has an interior surface coated with a capture material and forms a waveguide. At least one collimated light emitting diode is disposed proximate and perpendicular to the major axis of the at least one capillary tube and is positioned relative to the at least one capillary tube so that energy enters the at least one capillary tube from its exterior along the entire length of the at least one capillary tube to project a line of energy along substantially the entire longitudinal extent of the at least one capillary tube. A photosensor is disposed proximate the distal end of the at least one capillary tube for receiving emissive radiation therefrom. The photosensor generates an output voltage (or, optical output) representative of the emissive radiation, and a means for measuring the output voltage is provided. Also disclosed is a method of detecting target molecules in a sample using the biosensor of the present invention. | 04-11-2013 |
20130071558 | CORE-SHELL NANOPARTICLES WITH MULTIPLE CORES AND A METHOD FOR FABRICATING THEM - The present invention is directed toward core-shell nanoparticles, each comprising a ligand-capped metal shell surrounding a plurality of discrete, nonconcentric, metal-containing cores. Methods of making and using these nanoparticles are also disclosed. | 03-21-2013 |
20120189151 | ROBUST DIAPHRAGM FOR AN ACOUSTIC DEVICE - A rigid, flat plate diaphragm for an acoustic device is illustrated. The internal supporting structure of the diaphragm provides a combination of torsional and translational stiffeners, which resemble a number of crossbars. These stiffeners brace and support the diaphragm motion, thus causing its response to not be adversely affected by fabrication stresses and causing it to be very similar in dynamic response to an ideal flat plate operating in a frequency range that extends well beyond the audible. | 07-26-2012 |
20120186822 | MODULAR PRESSURE MANAGEMENT OIL SPILL CONTAINMENT SYSTEM AND METHOD - A modular pressure management oil spill containment system is constructed on the floor of an ocean to contain an oil spill caused by a wild well blowout. A base containment module including a hollow wall and at least one pressure relief valve is submerged below a surface of the ocean, positioned on a portion of the ocean floor that circumvents the wild well and its hollow wall is reinforced. At least one additional containment module including a hollow wall and at least one pressure relief valve is submerged below the ocean surface, positioned on top of the base containment module and its hollow wall is also reinforced. A plurality of riser assemblies are connected between at least a portion of the pressure relief valves of the containment modules and at least one containment vessel. The pressure relief valves are controlled to manage the containment of the oil spill. | 07-26-2012 |
20120146099 | RECONFIGURABLE RF/DIGITAL HYBRID 3D INTERCONNECT - Reconfigurable | 06-14-2012 |
20120034280 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND AND AN ANTI-MICROBIAL AGENT - Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one E | 02-09-2012 |
20110105355 | BORRELIA BURGDORFERI CELL ENVELOPE PROTEIN ARRAY - Methods of assessing a sample for the presence of antibodies to cell envelope proteins of | 05-05-2011 |
20110061538 | Method of Altering A Fluid-Borne Contaminant - An improved method of purifying a fluid having fluid-borne contaminants I including the steps of: providing a pump ( | 03-17-2011 |
20110038492 | OPTICAL SENSING IN A DIRECTIONAL MEMS MICROPHONE - A microphone having an optical component for converting the sound-induced motion of the diaphragm into an electronic signal using a diffraction grating. The microphone with inter-digitated fingers is fabricated on a silicon substrate using a combination of surface and bulk micromachining techniques. A 1 mm×2 mm microphone diaphragm, made of polysilicon, has stiffeners and hinge supports to ensure that it responds like a rigid body on flexible hinges. The diaphragm is designed to respond to pressure gradients, giving it a first order directional response to incident sound. This mechanical structure is integrated with a compact optoelectronic readout system that displays results based on optical interferometry. | 02-17-2011 |
20100292096 | STRAIN AND SPECIES-SPECIFIC BORRELIA PROTEIN ARRAY - Methods of assessing a sample for the presence of antibodies to certain proteins of | 11-18-2010 |
20100203513 | MICRORNA AS BIOMARKER IN CANCER - The present invention relates to the discovery of certain microRNAs that correlate with certain information regarding cancer. The microRNAs of the invention are selected from the group consisting of hsa-miR-15b, hsa-miR-181b, hsa-miR-191, hsa-miR-200c, and hsa-let-7g. If the expression of these microRNAs is increase, then the increased expression of these microRNAs is diagnostic for cancer, characterizes the cancer, prognosticates an expected response to cancer treatments, and/or prognosticates an expected survival of a patient. Embodiments of this discovery include a method, composition, kit and isolated nucleic acid. | 08-12-2010 |
20100187106 | ULTRA-SENSITIVE, PORTABLE CAPILLARY SENSOR - A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its interior surface. The specific capture antibody is selected based upon a desired target analyte to be detected. A sample potentially containing the target antigen is introduced into the capillary tube. Thereafter, a second antibody labeled with a fluorescent dye is introduced. Upon excitation by electromagnetic energy, typically supplied by a laser, the fluorescence of the sample is captured and analyzed. The apparatus is extremely compact and rugged making it ideal for field use. In addition, accurate results may be obtained by relatively unskilled operators directly from a self-contained readout. Optionally, an external device (e.g., a computer) may be connected to the apparatus via an optional interface. The analysis time provided by the biosensor system of the invention is shorter than has heretofore been possible. | 07-29-2010 |
20100152819 | METHOD FOR ENHANCING BLOOD AND LYMPH FLOW IN THE EXTREMITIES - Methods for enhancing blood and lymph flow in the extremities of a human subject are disclosed. In one aspect, the methods rely on a stimulus effective to displace the skin of a plantar or palmer surface of the subject, thereby enhancing blood and lymph flow in the extremity associated with the stimulated plantar or palmer surface. In another aspect, the methods rely on an electrical stimulus to directly stimulate cutaneous receptors in a plantar or palmer surface of the subject, thereby enhancing blood and lymph flow in the extremity associated with the stimulated cutaneous receptors. Apparatus for enhancing blood and lymph flow in the extremities of a human subject according to the methods of the present invention are also disclosed. | 06-17-2010 |
20090306261 | Compatibilizing Polymer Blends by Using Organoclay - A method for producing a polymer blend that includes: combining a first polymer, a second polymer and an organoclay to form a mixture, wherein the first polymer is not compatible with the second polymer, and heating the polymer and organoclay mixture to form a compatilized polymer blend. The preferred organoclay is montmorillonite clay functionalized by an intercalation agent. The intercalation agent is a reaction product of a polyamine and an alkyl halide in a polar solvent. | 12-10-2009 |
20090247860 | SPECTRAL BIOMARKER AND ALGORITHM FOR THE IDENTIFICATION AND DETECTION OF NEURAL STEM AND PROGENITOR CELLS AND THEIR USE IN STUDYING MAMMALIAN BRAINS - The disclosure provides a biomarker and algorithm for identifying and detecting neural stem and progenitor cells and their use in studying mammalian brains. The disclosure further provides magnetic resonance spectroscopy methods and an image enhancing algorithm for the study of the proliferation of these cells and the associated neurogenesis in the live mammalian brain. | 10-01-2009 |
20090103084 | OXYGEN SENSOR FOR USE IN HARSH, ESPECIALLY HIGH, pH ENVIRONMENTS - An oxygen sensor usable and accurate in solutions of up to pH 14 is featured. The sensor is fabricated by immobilizing a layer of polystyrene mixed with a fluorophore (e.g., Ruthenium tris(4,7-diphenyl-1,10-phenanthroline) dichloride) in a solvent such as dichloromethane. The mixture may be coated onto a structure such as a stainless steel sensor probe. In typical use, the inventive sensor probe is inserted into a flow cell through which the solution to be monitored flows. A blue LED light source having a wavelength of approximately 470 nm, and a spectrophotometer detector complete the sensor system. In operation, the fluorophore layer of the probe is illuminated by a blue LED light and the fluorescence is reflected back to the spectrophotometer. The monitored solution, typically an electroless gold plating bath, is pumped from the process equipment through the flow cell, and then back to the solution's origin. | 04-23-2009 |
20090092629 | VACCINE FOR NONTYPEABLE HAEMOPHILUS INFLUENZAE INFECTION - This invention provides a method for identifying strains of nontypeable | 04-09-2009 |
20090049890 | MULTI-MODULED NANOPARTICLE-STRUCTURED SENSING ARRAY AND PATTERN RECOGNITION DEVICE FOR DETECTION OF ACETONE IN BREATH - The present invention is directed toward a multi-moduled nanoparticle-structured sensing array and pattern recognition device for detection of acetone in breath. | 02-26-2009 |
20080317815 | Induction of a physiological dispersion response in bacterial cells in a biofilm - One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising: | 12-25-2008 |
20080316480 | AGGREGATES OF PLURAL TRANSITION METAL NANOPARTICLES AND PLURAL CYANINE DYE MOLECULES - The present invention is directed to an aggregate composed of a plurality of nanoparticles of a transition metal and a plurality of cyanine dye molecules that are interacting non-covalently. The nanoparticles are capped with a capping molecule, while the cyanine dye molecule can be cationic, anionic, or neutral cyanine dye. Methods of making such aggregates and for using them in detection of an analyte are also disclosed. | 12-25-2008 |
20080278181 | OXIDATION-RESISTANT, LIGAND-CAPPED COPPER NANOPARTICLES AND METHODS FOR FABRICATING THEM - The present invention is directed toward oxidation-resistant, ligand-capped nanoparticles, each comprising one or more capping ligands on a copper-containing core. Methods of making and using these nanoparticles are also disclosed. | 11-13-2008 |
20080226917 | CORE-SHELL NANOPARTICLES WITH MULTIPLE CORES AND A METHOD FOR FABRICATING THEM - The present invention is directed toward core-shell nanoparticles, each comprising a ligand-capped metal shell surrounding a plurality of discrete, nonconcentric, metal-containing cores. Methods of making and using these nanoparticles are also disclosed. | 09-18-2008 |