NORTH CAROLINA STATE UNIVERSITY Patent applications |
Patent application number | Title | Published |
20160120142 | COMPOSITIONS AND METHODS FOR MINIMIZING NORNICOTINE SYNTHESIS IN TOBACCO - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in tobacco plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for a root-specific nicotine demethylases, CYP82E10, and variants thereof, that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Compositions of the invention also include tobacco plants, or plant parts thereof, comprising a mutation in a gene encoding a CYP82E10 nicotine demethylase, wherein the mutation results in reduced expression or function of the CYP82E10 nicotine demethylase. Seed of these tobacco plants, or progeny thereof, and tobacco products prepared from the tobacco plants of the invention, or from plant parts or progeny thereof, are also provided. Methods for reducing the level of nornicotine, or reducing the rate of conversion of nicotine to nornicotine, in a tobacco plant, or plant part thereof are also provided. The methods comprise introducing into the genome of a tobacco plant a mutation within at least one allele of each of at least three nicotine demethylase genes, wherein the mutation reduces expression of the nicotine demethylase gene, and wherein a first of these nicotine demethylase genes encodes a root-specific nicotine demethylase involved in the metabolic conversion of nicotine to nornicotine in a tobacco plant or a plant part thereof. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products. | 05-05-2016 |
20160114698 | METHOD AND APPARATUS FOR ANALYZING DATA RELATED TO VEHICLE RANGE ESTIMATION - A method of analyzing data related to a driving range estimation of a vehicle includes collecting attribute data related to the driving range estimation of the vehicle, analyzing a correlation between the attribute data and a driving range of the vehicle, generating a vehicle driving range estimation model based on the analyzed correlation, and analyzing a sensitivity between the vehicle driving range estimation model and the attribute data. | 04-28-2016 |
20160100548 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 04-14-2016 |
20150334890 | Blueberry plant named 'Pinnacle' - ‘Pinnacle’ is a new and distinct variety of blueberry plant that has the following unique combination of desirable features outstanding in a new variety.
| 11-19-2015 |
20150299795 | CANCER-ASSOCIATED GERM-LINE AND SOMATIC MARKERS AND USES THEREOF - The invention provides methods and compositions for identifying subjects, including canine subjects, having an elevated risk of developing cancer or having an undiagnosed cancer. These subjects are identified based on the presence of germ-line allele(s) and markers and various somatic mutations. | 10-22-2015 |
20150294796 | ASSEMBLIES AND METHODS OF STABILIZATION - Some embodiments of the present invention provide an assembly for harvesting light comprising a first molecule joined to a metal oxide surface through a surface linking group and a second molecule joined to the metal oxide surface. Such assemblies can harvest light to do useful chemistry, such as in a dye-sensitized photoelectrochemical cell, or a molecular catalyst-solar cell system. In other embodiments, the harvested light can be converted into electricity, such as in a dye-sensitized solar cell. Other embodiments of the present invention provide methods for stabilizing a chromophore or a catalyst on a surface. These methods are applicable, for example, to dye-sensitized photoelectrochemical cells where the surface-bound chromophores are known to be unstable under aqueous conditions. | 10-15-2015 |
20150290354 | NONWOVEN FIBER MATERIALS - The present invention provides electrospun fibrous materials with various potential applications in the healthcare industry. Unique fiber morphologies are provided, which can allow the fibrous materials to exhibit a range of desirable properties. The electrospun fibrous materials are advantageously biocompatible and may be tailored for certain specific applications, e.g., by the incorporation of one or more therapeutic agents. Exemplary materials described herein can be employed in controlled, localized drug delivery, tissue engineering, and wound healing applications. | 10-15-2015 |
20150282401 | Interspecific Hybrid Flowering Pear 'NCPX1' - ‘NCPX1’ is a new cultivar of hybrid flowering pear with a narrow fastigiated habit, red to purple flower buds opening with white flower petals and a high level of resistance to fire blight. | 10-01-2015 |
20150271977 | Miscanthus sinensis Grass named 'NCMS1' - ‘NCMS1’ is a new | 09-24-2015 |
20150239049 | SYNTHESIS OF NANOSTRUCTURES - A method for making a nanostructure is provided. The method includes adding a seed solution to a first aqueous growth solution to produce a nanoparticle solution in a first growth phase and continuously adding a second growth solution to the nanoparticle solution to form a nanostructure in a second growth phase. Related nanostructures are also provided. | 08-27-2015 |
20150211030 | SEQUESTRATION OF CARBON DIOXIDE WITH HYDROGEN TO USEFUL PRODUCTS - Provided herein are genetically engineered microbes that include at least a portion of a carbon fixation pathway, and in one embodiment, use molecular hydrogen to drive carbon dioxide fixation. In one embodiment, the genetically engineered microbe is modified to convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof at levels greater than a control microbe. Other products may also be produced. Also provided herein are cell free compositions that convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof. Also provided herein are methods of using the genetically engineered microbes and the cell free compositions. | 07-30-2015 |
20150173406 | HYPOALLERGENIC FOOD-GRADE PROTEIN MATRICES AND USES THEREOF - This invention relates generally to the discovery of improved food-grade protein matrices with reduced allergeiiicity and uses thereof including immunotherapy. | 06-25-2015 |
20150089696 | Albizia julibrissin tree name 'NCAJ1' - ‘NCAJ1’ is a new | 03-26-2015 |
20150072852 | Solar Water Splitting in a Molecular Photoelectrochemical Cell - A Dye Sensitized Photoelectrosynthesis Cell (DSPEC) splits water with visible light using a derivatized, core/shell nanostructured photoanode with the core having a high surface area conductive metal oxide film—such as nanoITO (indium tin oxide) or nanoATO (antimony tin oxide)—coated with a thin outer shell of, for example, TiO | 03-12-2015 |
20150064492 | PATTERNED FILMS, LAYERED COMPOSITES FORMED THEREWITH, AND METHODS OF PREPARATION THEREOF - The present disclosure provides materials exhibiting improved properties arising from a surface treatment thereof. In particular, thin films can be provided with a patterned surface, the patterned thin films exhibiting improved properties such as in relation to coercivity, mechanical coupling, and magnetic coupling. The disclosure further provides layered composites comprising one or more patterned thin films. The disclosure also provides methods of forming patterned thin films. | 03-05-2015 |
20150052651 | Buddleja plant named 'Pink Micro Chip' - ‘Pink Micro Chip’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety.
| 02-19-2015 |
20150052650 | Buddleja plant named 'Blue Chip Jr' - ‘Blue Chip Jr’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety.
| 02-19-2015 |
20150033428 | Hypericum plant named 'NCHC1' - ‘NCHC1’ is a new | 01-29-2015 |
20150033425 | Deutzia plant named 'NCDX1' - ‘NCDX1’ is a new | 01-29-2015 |
20150033424 | Beautyberry plant named 'NCCX1' - ‘NCCX1’ is a new beautyberry plant particularly distinguished by an upright rounded habit, pink/purple flower color (RHS 75A), purple young shoots and emerging leaves, long peduncles and abundant purple fruit. | 01-29-2015 |
20150025500 | APPARATUS AND METHOD FOR INTRAOSSEOUS FLUID INFUSION - A system allows for rapid intraosseous delivery of fluids from a fluid reservoir via an intraosseous port having a tip disposed within the bone marrow of a patient. The system includes a housing with a chamber and a plunger. An actuator is moveable between first and second positions to move the plunger between the distal and proximal positions. A valve housing includes a first one-way valve fluidly coupled to the fluid reservoir, and a second one-way valve fluidly coupled to the intraosseous port. The valves of the valve housing are oriented such that movement of the actuator from the first to the second position moves the plunger from the distal to the proximal position, drawing fluid from the fluid reservoir through the first valve and into the chamber. Movement of the actuator from the second to the first position moves the plunger from the proximal to the distal position, driving fluid from the chamber through the port and second valve and through the intraosseous port. A grip manipulated by a user effects movement of the actuator, which provides sufficient mechanical advantage for the user to easily overcome resistance to the flow of fluid into the bone marrow. The plunger may be biased in the proximal position such that it is automatically retracted to that position, causing re-filling of the chamber, when the user releases forces imparted to the grip. The tubing and valve mechanism are of sufficient caliber to allow rapid and low-resistance flow of fluid from the reservoir into the chamber. The combination of these components allows rapid infusion of large volumes into the bone marrow without user fatigue, and requiring only one hand to operate the mechanism. | 01-22-2015 |
20140371286 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS - A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II | 12-18-2014 |
20140366234 | Industrial sweetpotato plant named 'NCPUR06-020' - ‘NCPUR06-020’ is a purple-fleshed sweetpotato with high levels of anthocyanin pigments in its storage roots. ‘NCPUR06-020’ was developed using conventional crossing and breeding methods, and it is intended for use in the natural colorant industry. The anthocyanins present in sweetpotatoes have a number of beneficial properties and they can be used for a wide range of purposes in the food processing and functional food industries. | 12-11-2014 |
20140353166 | NOVEL PROCESS FOR SCALABLE SYNTHESIS OF MOLYBDENUM DISULFIDE MONOLAYER AND FEW-LAYER FILMS - The present disclosure relates to nanosheet synthesis. More particularly, the present disclosure relates to molybdenum sulfide (MoS | 12-04-2014 |
20140350877 | BATTERY PARAMETERS, STATE OF CHARGE (SOC), AND STATE OF HEALTH (SOH) CO-ESTIMATION - Battery parameters, state of charge, and state of health co-estimation are disclosed. According to an aspect, a method includes determining a terminal current and a terminal voltage of a battery. The method also includes maintaining a battery model that defines a relationship between a parameter of the battery, the terminal current, and the terminal voltage. Further, the method includes determining the parameter of the battery based on the battery model and the acquired terminal current and the terminal voltage. | 11-27-2014 |
20140341582 | SYSTEMS AND METHODS FOR SINGLE WAVELENGTH WITH DUAL CHANNELS FOR CONTROL SIGNAL AND INTERNET DATA TRANSMISSION - Systems and methods for single wavelength with dual channels for control signal and Internet data transmission are disclosed. According to an aspect, a network unit may include a communications module configured to receive a single wavelength signal having first and second channels. The first channel may carry Internet data. The second channel may carry power grid control and monitoring data. Further, the network unit may include a multiplexer configured to multiplex the Internet data and the power grid control and monitoring data. | 11-20-2014 |
20140318593 | NANOPARTICLE COMPACT MATERIALS FOR THERMOELECTRIC APPLICATION - A thermoelectric composite and a thermoelectric device and a method of making the thermoelectric composite. The thermoelectric composite is a semiconductor material formed from mechanically-alloyed powders of elemental constituents of the semiconductor material to produce nano-particles of the semiconductor material, and compacted to have at least a bifurcated grain structure. The bifurcated grain structure has at least two different grain sizes including small size grains in a range of 2-200 nm and large size grains in a range of 0.5 to 5 microns. The semiconductor material has a figure of merit ZT, defined as a ratio of the product of square of Seebeck coefficient, S | 10-30-2014 |
20140287230 | NANOSTRUCTURED POLYMER-INORGANIC FIBER MEDIA - A fiber media and a filter device. The fiber media has a plurality of nanofibers formed of a polymer material, having diameters less than 1 micron, and formed into a fiber mat. A barrier layer is disposed on the nanofibers to prevent dissolution of the nanofibers in the fiber mat upon exposure of the fiber mat to a solvent of the polymer material. The barrier layer coated nanofibers have a maximum strain before breakage of at least 2%. The filter device includes the fiber media and a support attached to the fiber mat. | 09-25-2014 |
20140275213 | Methods and Compositions for Plant Pest Control - The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NOs: 1-142, a fragment or variant thereof, or a complement thereof, or a polypeptide sequence comprising any one of SEQ ID NOs: 143-159, a fragment or variant thereof. | 09-18-2014 |
20140262789 | VERY HIGH FREQUENCY (VHF) DRIVEN ATMOSPHERIC PLASMA SOURCES AND POINT OF USE FERTIGATION OF IRRIGATION WATER UTILIZING PLASMA PRODUCTION OF NITROGEN BEARING SPECIES - A point of use irrigation water fertigation system utilizes plasma production of nitrogen-bearing species. Soluble nitrogen-bearing species are generated using an atmospheric air plasma treatment of an irrigation water supply. A plasma is generated by a tube having an air intake. A high frequency generator generates atmospheric plasma. The end of the tube is placed above the surface of the irrigation water supply and the plasma emanating from the tube generates nitrogen species in the water. The non-thermal plasma discharge efficiently produces highly reactive radicals and NO | 09-18-2014 |
20140261646 | ADVANCED SEMICONDUCTOR-CONDUCTOR COMPOSITE PARTICLE STRUCTURES FOR SOLAR ENERGY CONVERSION - An electrode for solar conversion including a porous structure configured to contain therein at least one of a catalyst, a chromophore, and a redox couple. The porous structure has a set of electrically conductive nanoparticles adjoining each other. The set of electrically conductive nanoparticles forms a meandering electrical path connecting the nanoparticles together. The porous structure has an atomic layer by layer deposited semiconductive coating disposed conformally on the electrically conductive nanoparticles to form an exterior surface for reception of charge carriers. | 09-18-2014 |
20140256545 | FUNCTIONALIZED ENVIRONMENTALLY BENIGN NANOPARTICLES - This invention is directed to the preparation and applications of internally and/or externally functionalized environmentally benign nanoparticles (EbNPs), which are produced by a three step procedure: (1) synthesis of native EbNPs, (2) functionalization with active agents, and (3) additional surface property customization via one or more modifier(s). | 09-11-2014 |
20140255386 | MICRORNA MODULATORS AND METHOD FOR IDENTIFYING AND USING THE SAME - The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is operably linked to a nucleic acid molecule encoding a reporter protein, with a test agent and determining whether the test agent increases or decreases the expression of the reporter protein thereby identifying a microRNA modulator. Antagonists identified by this screening assay are provided, as are methods for using the same to inhibit microRNA activity and prevent or treat disease. | 09-11-2014 |
20140251353 | Tobacco Inbred and Hybrid Plants and Uses Thereof - The present disclosure provides tobacco inbred plants TN90 SRC, CMS TN90 SRC, KY14 SRC, CMS KY14 SRC, L8 SRC, NC775 SRC, CMS NC775 SRC, NC645 SRC, NC638 SRC, CMS NC638 SRC, TN86 SRC, and CMS TN86 SRC, and hybrids KY14 X L8 SRC, NC7 SRC, and NCBH129 SRC. The present disclosure also provides parts of such plants and products made from those parts. The present disclosure also includes progeny of the provided plants including hybrids. | 09-11-2014 |
20140248687 | METHODS FOR EXPRESSING POLYPEPTIDES IN HYPERTHERMOPHILES - Provided herein are genetically engineered archaea. A genetically engineered archaea includes a heterologous polynucleotide that has a promoter operably linked to a coding region, where the coding region encodes a polypeptide having optimal activity below the optimum growth temperature (T | 09-04-2014 |
20140248058 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR PROVIDING SMART UNDERWATER FREE SPACE OPTICAL COMMUNICATIONS - Methods, systems, and computer readable for providing smart underwater free space optical communications are provided. According to one aspect, a system for smart underwater free space optical communications is provided. The system includes a receiver. The receiver includes an optical detector array for detecting incident light under water. The receiver further includes a compound lens array located optically in front of the optical detector. The compound lens array includes lenses that steer incident light arriving at different angles to different portions of the optical detector array. A controller processes signals generated by the optical detector based on the incident light and controls an aspect of the underwater communications based on the steered incident light detected by the detector array. Components of the controller may include a backscatter estimator and an angle of arrival estimator for estimating water quality obtained from backscattered light and an angle of arrival of incident light, respectively. | 09-04-2014 |
20140246036 | TRANSCRIPTION FACTORS THAT REGULATE NICOTINE BIOSYNTHESIS IN TOBACCO - The present invention provides nucleic acids encoding transcription factors and methods of using these nucleic acids to modulate nicotine production in plants and to produce plants having modulated nicotine production. | 09-04-2014 |
20140241163 | RECEIVER-BASED METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR CONTROLLING TCP SENDER BEHAVIOR IN MOBILE COMMUNICATIONS NETWORKS WITH LARGE BUFFER SIZES - Receiver-based methods for controlling TCP sender behavior in cellular communications networks with large buffer sizes are disclosed. One method includes, at a TCP receiver, receiving packets from a TCP sender. The method further includes determining, based on the packets, a minimum round trip time and a moving average round trip time for cellular network carrying the packets between a TCP sender and a TCP receiver. The method further includes adaptably adjusting a received window size to advertise to the TCP sender based on the minimum round trip time and the moving average round trip time. The method further includes advertising the adjusted received window sizes to the TCP sender. | 08-28-2014 |
20140206021 | PRION PROTEIN LIGANDS AND METHODS OF USE - Ligands that bind to prion proteins and methods for using the ligands for detecting or removing a prion protein from a sample, such as a biological fluid or an environmental sample. The ligands are capable of binding to one or more forms of prion protein including cellular prion protein (PrPc), infectious prion protein (PrPsc), and recombinant prion protein (PrPr). Prions from various species, including humans and hamsters, are bound by the ligands. Also provided is a method of treating or retarding the development of a prion-associated pathology in a subject | 07-24-2014 |
20140196730 | TOBACCO INBRED PLANTS K326 SRC, CMS K326 SRC, K346 SRC, CMS K346 SRC, NC1562-1 SRC, NCTG-61 SRC, CMS NCTG-61 SRC AND HYBRID NC196 SRC - The present disclosure provides tobacco inbred plants K326 SRC, CMS K326 SRC, K346 SRC, CMS K346 SRC, NC1562-1 SRC, NCTG-61 SRC, CMS NCTG-61 SRC and hybrid NC196 SRC. The present disclosure also provides parts of such plants and products made from those parts. The present disclosure also includes progeny of the provided plants including hybrids. | 07-17-2014 |
20140193855 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS - This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies. | 07-10-2014 |
20140155822 | ACTIVE CATHETER DEVICE AND ASSOCIATED SYSTEM AND METHOD - An active catheter device is provided. At least one elongate catheter segment includes an elongate flexible tube member defining an axis, and a pair of ferrule members operably engaged with and spaced apart along the tube member. The ferrule members are not rotatable about the axis relative to each other. At least one articulation member is operably engaged with and extends at least between the ferrule members along the tube member. Each articulation member is configured to be actuatable to cause a change in a distance between the ferrule members so as to articulate the tube member. Associated systems and methods are also provided. | 06-05-2014 |
20140150135 | Synthetic Pathway for Biological Carbon Dioxide Sequestration - This invention relates to methods for increasing carbon fixation and/or increasing biomass production in a plant, comprising: introducing into a plant, plant part, and/or plant cell one or more heterologous polynucleotides encoding polypeptides having the enzyme activity of succinyl CoA synthetase, 2-oxoglutarate:ferredoxin oxidoreductase, 2-oxoglutarate carboxylase, oxalosuccinate reductase and isocitrate lyase to produce a stably transformed plant, plant part, and/or plant cell expressing the one or more heterologous polynucleotides. The methods further comprise introducing into a plant, plant part or plant cell heterologous polynucleotides encoding polypeptides having the enzyme activity of glyoxylate carboligase and tartronic semialdehyde reductase, and/or heterologous polynucleotides encoding a superoxide reductase from an archaeon species, an aquaporin and/or an inhibitor of cell wall invertase inhibitor. Additionally, transformed plants, plant parts, and/or plant cells are provided as well as products produced from the transformed plants, plant parts, and/or plant cells. | 05-29-2014 |
20140137657 | REVERSIBLY DEFORMABLE AND MECHANICALLY TUNABLE FLUIDIC ANTENNAS - A method of manufacturing a fluidic structure is disclosed. A cavity that defines a shape of an element of the fluidic structure within a material is formed. The cavity is filled with liquid metal. The cavity is sealed. The fluidic structure behaves as an antenna. A fluidic antenna includes a material that defines a shape of the fluidic antenna by a cavity filled with liquid metal formed within the material, where the material further defines at least one mechanical property of the fluidic antenna. | 05-22-2014 |
20140127273 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. | 05-08-2014 |
20140106367 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS - Porphyrinic compounds that contain solubilizing groups are described, along with methods of making and using the same and compositions comprising such compounds. Examples of such compounds include compounds of Formula I: | 04-17-2014 |
20140093887 | PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY - The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A′-Z-B′-B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A′ is a linker group or covalent bond; B′ is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle. | 04-03-2014 |
20140079808 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator. | 03-20-2014 |
20140055901 | SOLID STATE FAULT ISOLATION DEVICES AND METHODS - Disclosed herein are solid state fault isolation devices and methods. According to one or more embodiments, a semiconductor current fault controlled device is provided. The device includes a semiconductor substrate of N-type conductivity. The substrate has opposed major surfaces. An anode region of P-type conductivity is formed in one major surface. A P-type buried layer is formed in a first portion of the other major surface. A junction field-effect transistor (JFET) is formed in a second portion of the other major surface. A P-type top layer is formed in the JFET and forms a channel defined by an overlap between the P-type buried layer and the P-type top layer. The channel laterally extends to the semiconductor substrate from a cathode region and being shielded from the anode region. | 02-27-2014 |
20140046257 | RAPID FLUID COOLING DEVICES AND METHODS FOR COOLING FLUIDS - A cooling device includes a target fluid inlet, a target fluid outlet, an inner conduit, and a chamber surrounding the inner conduit. The inner conduit communicates with the target fluid inlet and the target fluid outlet, and provides a flow path for a target fluid to be cooled. The chamber contains a first endothermic reactant and includes a reactant inlet selectively alterable from a closed state to an open state. When the reactant inlet is in the closed state, the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs. When the reactant inlet is in the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the target fluid in the inner conduit. | 02-13-2014 |
20140026673 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR TESTING CUTTING BLADE INTEGRITY - A system for evaluating integrity of a cutting blade includes at least one stress wave generator for generating at least one stress wave in a cutting blade under test. A sensor detects a signal generated by the at least one stress wave. An integrity analyzer coupled to the sensor determines an indication of integrity of the cutting blade based on at least one characteristic of the signal. | 01-30-2014 |
20140023691 | INHIBITION OF BACTERIAL BIOFILMS AND MICROBIAL GROWTH WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for imidazole derivative compounds useful to inhibit the formation of biofilms and/or inhibit microbial growth, compositions including these compounds, devices including these compounds, and methods of using the same. | 01-23-2014 |
20130335683 | POLARIZATION-INDEPENDENT LIQUID CRYSTAL DISPLAY DEVICES INCLUDING MULTIPLE POLARIZING GRATING ARRANGEMENTS AND RELATED DEVICES - A liquid crystal device includes a first polarization grating, a second polarization grating, and a liquid crystal layer. The first polarization grating is configured to polarize and diffract incident light into first and second beams having different polarizations and different directions of propagation relative to that of the incident light. The liquid crystal layer is configured to receive the first and second beams from the first polarization grating. The liquid crystal layer is configured to be switched between a first state that does not substantially affect respective polarizations of the first and second beams traveling therethrough, and a second state that alters the respective polarizations of the first and second beams traveling therethrough. The second polarization grating is configured to analyze and diffract the first and second beams from the liquid crystal layer to alter the different directions of propagation thereof in response to the state of the liquid crystal layer. Related devices are also discussed. | 12-19-2013 |
20130326736 | NEMATODE RESISTANT CROPS - Methods of inhibiting plant parasitic nematodes, methods of obtaining transgenic plants useful for inhibiting such nematodes, and transgenic plants that are resistant to plant parasitic nematodes through inhibition of plant nematode CLE peptide receptor genes are provided. Methods for expressing genes at plant parasitic nematode feeding sites with plant nematode CLE peptide receptor gene promoters are also provided, along with nematode CLE peptide receptor gene promoters that are useful for expressing genes in nematode feeding sites as well as transgenic plants and nematode resistant transgenic plants comprising the promoters. | 12-05-2013 |
20130324493 | COMPOSITIONS COMPRISING NINGNANMYCIN AND USES THEREFOR - Provided herein are compositions comprising ningnanmycin or a derivative thereof, as well as their use for controlling or combating a fungal infection in a plant or plant part (e.g., a turfgrass). | 12-05-2013 |
20130323803 | METHODS AND COMPOSITIONS FOR THE PRODUCTION OF EXTREMOPHILE ENZYMES FROM GREEN MICROALGAE AND CYANOBACTERIA - The present invention relates to compositions and methods for stable transformation of green microalgae and for production of transgenic green microalgae and/or cyanobacteria that produce extremophile enzymes as co-products during the growth of the green microalgae and/or cyanobacteria for lipid biofuel production. Thus, the present invention provides nucleic acid constructs and methods of transformation useful in the production of stably transformed green microalgae and/or cyanobacteria expressing extremophile enzymes in combination with lipid production for biofuel. | 12-05-2013 |
20130315874 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator. | 11-28-2013 |
20130310265 | METHODS OF PREPARING CYCLIC PEPTIDES AND USES THEREOF - This invention is directed to the discovery of improved methods of preparing cyclic peptides, cyclic peptide esters, cyclic peptide amidines, and libraries of these compounds. The invention also includes uses of these compounds and libraries for screens as drugs and binders of biologics. | 11-21-2013 |
20130296741 | ANKLE-FOOT ORTHOTIC DEVICES WITH INTEGRATED VIBROTACTILE BIOFEEDBACK AND RELATED METHODS - Ankle-foot orthotic devices with integrated vibrotactile biofeedback and related methods are disclosed. According to an aspect, an ankle-foot orthotic device may include one or more sensors configured to determine a gait phase of a user and to determine a movement of the user. Further, the device may include a controller configured to communicate feedback to the user based on the determined gait phase and the determined movement of the user. | 11-07-2013 |
20130289685 | IMPLANTATION TOOLS FOR SPINAL CORD STIMULATOR LEADS AND RELATED METHODS - Implantation tools for spinal cord stimulator leads and related methods are disclosed. According to an aspect, an implantation tool may include an elongated body having first and second ends. The elongated body may define an interior extending between the first and second ends. The first end may be configured for connection to a vacuum pump for drawing air through the interior in a direction generally from the second end towards the first end. The second end may define an opening for engaging a lead of the spinal cord stimulator when air is drawn by the vacuum pump. | 10-31-2013 |
20130281503 | MODULATION OF RESPONSE REGULATORS BY IMIDAZOLE DERIVATIVES - The present disclosure provides methods and compositions useful for screening agents for activity in modulating response regulator signaling activity, which is, in turn, useful for determining whether these agents modulate biofilm formation or lowers the minimum inhibitory concentration (MIC) of an antibiotic, useful in determining or selecting optimum agents and/or agent dosages in modulating a biofilm of interest or lowering the minimum inhibitory concentration (MIC) of an antibiotic, and useful as a research tool for studying response regulators. | 10-24-2013 |
20130276801 | METHOD FOR PRODUCING MICROCRYSTALLINE CELLULOSE FROM TOBACCO AND RELATED TOBACCO PRODUCT - Methods for producing dissolving grade pulp and microcrystalline cellulose from tobacco are provided. The methods include chemical pulping a tobacco input to form a tobacco pulp. Chemical pulping the tobacco input includes combining the tobacco input with a strong base defining a weight from about 5% to about 50% of the tobacco input, and heating the tobacco input and the strong base with an H-factor from about 500 to about 3,300. Further, the methods include bleaching the tobacco pulp to produce a dissolving grade pulp. Bleaching the tobacco pulp may include chlorination of the tobacco pulp with a chlorine dioxide solution, and caustic extraction of the tobacco pulp with a second strong base. A related tobacco-derived microcrystalline cellulose product is also provided, which can be used as a binder, a filler, and/or a texturizer in a tobacco product, such as a smokeless tobacco product. | 10-24-2013 |
20130259834 | COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTIC PEPTIDES - Methods and compositions for targeted delivery of biotherapeutics are provided. The compositions comprise bile-sensitive | 10-03-2013 |
20130255216 | HIGH VALUE LIGNIN DERIVATIVES, POLYMERS, AND COPOLYMERS AND USE THEREOF IN THERMOPLASTIC, THERMOSET, COMPOSITE, AND CARBON FIBER APPLICATIONS - The present disclosure relates to reactive modified lignin, methods of preparing such modified lignin, and materials, such as polymer systems, incorporating the modified lignin. More specifically, the lignin can be modified by selectively masking reactive functional groups such that the material has a modulated reactivity and is thus better suited for incorporation into and/or formation of further materials, such as carbon fibers. | 10-03-2013 |
20130234669 | INTELLIGENT INTEGRATED BATTERY MODULE - An energy storage system is provided. The system includes a plurality of energy storage modules connected in parallel. Each energy storage module has an energy storage source, a bidirectional current converter configured for supplying charge to the energy storage source from a power source and for discharging current for use by an electrical device, a monitoring module for monitoring the energy storage source and the current converter, and a controller configured to control the current converter based upon monitored characteristics of the storage source and the current converter to produce a respective output signal for each module. A communications module is in connection with each output signal of the energy storage modules and configured for communicating a combined output signal with one of the power source and the electrical device. | 09-12-2013 |
20130224153 | RECOMBINANT LACTOBACILLUS WITH DECREASED LIPOTEICHOIC ACID TO REDUCE INFLAMMATORY RESPONSES - Methods and compositions for treating or preventing inflammatory disorders are provided. The compositions of the invention comprise a recombinant bacterium genetically modified to decrease the display of lipoteichoic acid on the cell surface. Methods of the invention comprise administering to a subject a recombinant bacterium modified to decrease the display of lipoteichoic acid on the cell surface. Administration of the recombinant bacterium promotes a desired therapeutic response. The recombinant bacterium may be administered in a single dose or series of doses. Methods of the invention find use in treating or preventing a variety of inflammatory disorders including, for example, treating or preventing inflammatory bowel disease, colitis, or Crohn's disease. | 08-29-2013 |
20130216829 | METHOD AND APPARATUS FOR MAKING AN IMPROVED HIGH SURFACE AREA FIBER - The present invention is directed to a high surface area fiber and method for making the same. The fiber includes a co-extruded internal fiber and an external sheath that is washed with a solvent to remove the dissolvable external sheath, the resulting fiber having a longitudinal axis and a cross-section, the cross-section having a middle region and projections extending from the middle region. | 08-22-2013 |
20130200391 | GALLIUM NITRIDE BASED STRUCTURES WITH EMBEDDED VOIDS AND METHODS FOR THEIR FABRICATION - A gallium nitride-based structure includes a substrate, a first layer of gallium nitride disposed on a growth surface of the substrate, and a second gallium nitride layer disposed on the first gallium nitride layer. The first layer includes a region in which a plurality of voids is dispersed. The second layer has a lower defect density than the gallium nitride of the interfacial region. The gallium nitride-based structure is fabricated by depositing GaN on the growth surface to form the first layer, forming a plurality of gallium nitride nanowires by removing gallium nitride from the first layer, and growing additional GaN from facets of the nanowires. Gallium nitride crystals growing from neighboring facets coalesce to form a continuous second layer, below which the voids are dispersed in the first layer. The voids serve as sinks or traps for crystallographic defects, and also as expansion joints that ameliorate thermal mismatch between the Ga.N and the underlying substrate. The voids also provide improved light transmission properties in optoelectronic applications. | 08-08-2013 |
20130199692 | Surface Functionalization of Polyester - Methods for surface treatment of polyester substrates are described. Treatment methods include adherence of a polymer layer on a surface of the polyester so as to increase the hydrophilic properties of the surface. Polymers can be polyelectrolytes that are adsorbed at the surface or polymer brushes that are polymerized at the surface. Further surface functionalization can include the adherence of inorganic nanoparticles to the surface. The polyester substrates can be recycled polyester such as recycled polyethylene terephthalate that has been subjected to a partial saponification reaction during the recycling process. | 08-08-2013 |
20130183761 | Methods for Incorporating Unnatural Amino Acids in Eukaryotic Cells - The invention relates to a nucleic acid comprising a nucleotide sequence encoding a tRNA orthogonal to a eukaryotic cell, said nucleotide sequence operably linked to a promoter capable of directing transcription by eukaryotic RNA polymerase III. The invention also relates to methods for incorporating unnatural amino acids in eukaryotic cells using same. | 07-18-2013 |
20130165539 | ALKALINE-STABLE CHROMATOGRAPHIC RESINS - This invention is directed to the production of improved chromatographic resins and method of making and using such resins. | 06-27-2013 |
20130165007 | MICRO AND NANOFIBER NONWOVEN SPUNBONDED FABRIC - The invention provides methods for the preparation of nonwoven spunbonded fabrics and various materials prepared using such spunbonded fabrics. The method generally comprises extruding multicomponent fibers having an islands in the sea configuration such that upon removal of the sea component, the island components remain as micro- and nanofibers. The method further comprises mechanically entangling the multicomponent fibers to provide a nonwoven spunbonded fabric exhibiting superior strength and durability without the need for thermal bonding. | 06-27-2013 |
20130137575 | CYCLOPROPENE AMINE COMPOUNDS - Methods of applying cyclopropene amine derivatives and compositions thereof to inhibit ethylene receptors in plants and plant material are disclosed. Methods include applying to the plant an effective ethylene response-inhibiting amount of at least one cyclopropene amine compound or composition thereof. Cyclopropene amine compounds, enantiomers, stereoisomers or salts thereof are also provided. | 05-30-2013 |
20130125830 | LIVESTOCK INSECT-REMOVAL SYSTEMS AND RELATED METHODS - Livestock insect removal systems and related methods are disclosed. According to one aspect, a system can comprise a structure defining a pathway for passage of livestock. The system can also comprise a duct including first and second ends defining first and second openings, respectively. The first opening is positioned along the pathway such that the livestock moving through the pathway passes near the first opening. Further, the system comprises a vacuum device connected to the second opening and configured to draw air through the duct and away from an area surrounding the first opening such that one or more insects are displaced from the livestock or an area surrounding the livestock when the livestock passes near the first opening. The displaced insects can be drawn into the duct for placement in an insect trap. | 05-23-2013 |
20130122143 | UTILIZATION OF NON-NUTRITIVE ADSORBENTS TO SEQUESTER MYCOTOXINS DURING EXTRACTION OF PROTEIN OR OTHER VALUE ADDED COMPONENTS FROM MYCOTOXIN CONTAMINATED CEREAL OR SEED OIL MEAL - A method for the removal of mycotoxins from cereal or oil seed meal that includes the use of a mycotoxin sequestrant to form a food grade composition for human consumption wherein said composition contains no more or less than an FDA approved level of mycotoxin for a human food product. | 05-16-2013 |
20130102818 | PROCESS OF CONVERSION OF BIOMASS TO FUEL - The present invention is directed to processes for the direct conversion of lipidic biomass fuelstock to combustible fuels. In particular, the invention provides a process for the direct conversion of animal fats to transportations fuels suitable as replacement for petroleum-derived transportation fuels. In one embodiment, the method comprises the steps of hydrolyzing a lipidic biomass to form free fatty acids, catalytically deoxygenating the free fatty acids to form n-alkanes, and reforming at least a portion of the n-alkanes into a mixture of compounds in the correct chain length, conformations, and ratio to be useful transportation fuels. Particularly, the product prepared according to the invention comprises mixtures of hydrocarbon compounds selected from the group consisting of n-alkanes, isoalkanes, aromatics, cycloalkanes, and combinations thereof. | 04-25-2013 |
20130077040 | LOW-TWIST CHIRAL OPTICAL LAYERS AND RELATED FABRICATION METHODS - An optical element includes a first and second stacked birefringent layers. The first birefringent layer includes local anisotropy patterns having respective relative orientations that vary over a first thickness between opposing faces of the first birefringent layer to define a first twist angle. The second birefringent layer includes local anisotropy patterns having respective relative orientations that vary over a second thickness between opposing faces of the second birefringent layer to define a second twist angle different than the first twist angle. Related devices and fabrication methods are also discussed. | 03-28-2013 |
20130069709 | AC POWERED LOGIC CIRCUITS AND SYSTEMS INCLUDING SAME - AC powered logic circuits and systems including same are disclosed. According to one aspect, a system including a logic circuit powered using an alternating current (AC) power source includes at least one supply transistor connected to receive voltages of opposite phases from an AC power source such that the at least one supply transistor is strongly on during a first phase of the voltage of the AC power source and is strongly off during a second phase opposite the first phase of the voltage of the AC power source and at least one logic circuit connected to be powered by the AC power source through the at least one supply transistor and producing an output at an output terminal responsive to an input received at an input terminal. | 03-21-2013 |
20130068690 | ADSORPTION DEVICES, SYSTEMS AND METHODS - Adsorption devices, systems, and methods are provided. In one embodiment, an adsorption device includes a fabric and an adsorbing complex attached at least partially attached to a surface of the fabric, the adsorbing complex being reactive to selectively adsorb a substance from a liquid passing through the fabric to remove at least a portion of the substance from the liquid. In one embodiment, the adsorption device can be incorporated into an extracorporeal blood circuit adapted to filter phosphate from blood of a hemodialysis patient without altering chemistry of the blood. | 03-21-2013 |
20130066425 | PROCESSING OF BIOCOMPATIBLE COATING ON POLYMERIC IMPLANTS - The present invention provides polymeric substrates comprising a biocompatible coating and methods of preparation thereof. In particular, the coating may be a ceramic material, especially a calcium phosphate material, which may be functionally graded. The invention provides the ability to apply high quality coatings to polymeric substrates without damaging the substrate (e.g., melting the polymeric material). The functionally graded coating can provide crystalline calcium phosphate near the coating interface with the substrate and provide amorphous calcium phosphate at the outer surface of the coating. | 03-14-2013 |
20130059412 | IN-SITU POLYMERIZATION IN BULK HETEROJUNCTION ORGANIC DEVICES - Fabrication of bulk heterojunction organic devices are disclosed that utilize in-situ polymerization of an active component of the device or an in-situ polymerization of an additive that controls the device morphology. According to an aspect, a method for the synthesis of a BHJ photovoltaic film may comprise preparing a homogeneous solution comprising 2,5-dibromothiophene and/or 2,5-diiodothiophene, P3HT and PCBM. The method may also comprise preparing a thin film of the homogeneous solution on the solid surface of a material or an assembly capable of acting as an anode. Oxygen may be excluded from the environment where the thin film will be exposed to photopolymerization by placing the thin film and anode assembly in an inert-gas environment. The method also comprises exposing the liquid film to UV light for a sufficient duration of time and at a sufficient temperature to cause photopolymerization to occur. | 03-07-2013 |
20130051102 | ISOLATED SOFT-SWITCH SINGLE-STAGE AC-DC CONVERTER - An alternating current-to-direct current (AC-DC) converter is provided. The converter may include a transformer having a primary side and a secondary side. A first bi-directional switch and a first inductor may be connected in series between a positive terminal of an AC source and a first terminal of the primary side of the transformer. A second bi-directional switch and a second inductor may be connected between the positive terminal of the AC source and a second terminal of the primary side of the transformer and connected in parallel with the first bi-directional switch. | 02-28-2013 |
20130046218 | APPARATUS AND CLUTCH FOR USING CONTROLLED STORAGE AND RELEASE OF MECHANICAL ENERGY TO AID LOCOMOTION - The subject matter described herein includes an apparatus and a clutch for using controlled storage and release of mechanical energy to aid in locomotion. One exemplary apparatus includes a frame including an upper portion configured to mechanically couple to a leg of the subject on a calf side of an ankle joint of the subject and a lower portion pivotally attached to the upper portion configured to mechanically couple to a foot of the subject on a foot side of the ankle joint of the subject. The apparatus include a rotary clutch and an elastic element coupled between the upper and lower portions of the frame to control periods of energy storage and release by the elastic element. | 02-21-2013 |
20130040521 | Highly Oriented and Crystalline Thermoplastic Filaments and Method of Making Same - A melt-spun highly oriented and crystalline thermoplastic filament or fiber having a tenacity of at least about 10 g/d, an elongation less than about 15-%, and a modulus of at least about 130 g/d. A method of making highly oriented and crystalline thermoplastic filaments has been developed that comprises extruding a thermoplastic polymer to form at least one molten filament. The at least one molten filament is introduced into a horizontal liquid isothermal bath. The bath is maintained at a temperature between the glass transition temperature and the melting temperature of the thermoplastic polymer. The bath increases the tension along the molten filament to form at least one partially oriented and low crystalline filament. The partially oriented filament is drawn to form the highly oriented and crystalline filament. | 02-14-2013 |
20130037040 | COMPOSITIONS AND METHODS FOR MINIMIZING NORNICOTINE SYNTHESIS IN TOBACCO - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in tobacco plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for a root-specific nicotine demethylases, CYP82E10, and variants thereof, that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Compositions of the invention also include tobacco plants, or plant parts thereof, comprising a mutation in a gene encoding a CYP82E10 nicotine demethylase, wherein the mutation results in reduced expression or function of the CYP82E10 nicotine demethylase. Seed of these tobacco plants, or progeny thereof, and tobacco products prepared from the tobacco plants of the invention, or from plant parts or progeny thereof, are also provided. Methods for reducing the level of nornicotine, or reducing the rate of conversion of nicotine to nornicotine, in a tobacco plant, or plant part thereof are also provided. The methods comprise introducing into the genome of a tobacco plant a mutation within at least one allele of each of at least three nicotine demethylase genes, wherein the mutation reduces expression of the nicotine demethylase gene, and wherein a first of these nicotine demethylase genes encodes a root-specific nicotine demethylase involved in the metabolic conversion of nicotine to nornicotine in a tobacco plant or a plant part thereof. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products. | 02-14-2013 |
20130011834 | MEAN DNA COPY NUMBER OF CHROMOSOMAL REGIONS IS OF PROGNOSTIC SIGNIFICANCE IN CANCER - Methods for predicting a disease free time interval (DFI) for a cancer patient under consideration for initial or further chemotherapy treatment are disclosed. The methods include obtaining a biological sample from a patient and detecting a copy number of chromosome region A1 and/or C2. The mean copy number per cell is correlated with a DFI for the subject. The chemotherapy can include doxorubicin and/or L-asparaginase treatment. Also provided are kits for predicting DFI in a subject with cancer and computer readable storage media for performing the presently disclosed methods. | 01-10-2013 |
20130005759 | SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122 - MicroRNAs are a class of endogenous regulators of gene function. Aberrant regulation of microRNAs has been linked to various human diseases, most importantly cancer. Small molecule intervention of microRNA misregulation has the potential to provide new therapeutic approaches to such diseases. microRNA miR-122 is the most abundant microRNA in the liver and is involved in hepatocellular carcinoma development and hepatitis C virus (HCV) infection. Small molecule inhibitors and activators of the microRNA miR-122 are described, and methods for their identification are reported. These small molecule inhibitors reduce viral replication in liver cells and thus represent a new approach to the treatment of HCV infections. Moreover, small molecule activation of miR-122 in liver cancer cells selectively induced apoptosis through caspase activation, and thus has implications in cancer chemotherapy. | 01-03-2013 |
20130005573 | COMPOSITIONS AND METHODS OF USE FOR KETONES AND ALDEHYDES AS HERBICIDES - Compositions and methods of use for ketones and aldehydes as herbicides are disclosed herein. According to an aspect, a method includes applying an effective amount of an herbicide composition comprising an acyclic, chemically-synthesized or plant-derived ketone or aldehyde of the invention to a locus where undesirable vegetation is to be controlled. The plant-derived or synthesized ketone may be a 2-undecanone. Further, various other acyclic ketones and aldehydes and their derivatives may be used. | 01-03-2013 |
20120309250 | COMPOSITE INORGANIC/POLYMER FIBERS AND INORGANIC FIBRILS FABRICATED FROM SHEARED SOLUTIONS - Nanofibers are fabricated by introducing a mixture of a polymer solution and inorganic precursor into a dispersion medium and shearing the mixture. Liquid strands, streaks or droplets of the mixture are spun into elongated fibers that include inorganic fibrils. The resulting composite inorganic/polymer fibers may be provided as an end product. Alternatively, the polymer may be removed to liberate the inorganic fibrils, which may be of the same or smaller cross-section as the polymer fibers and may be provided as an end product. | 12-06-2012 |
20120282453 | CARBON NANOTUBE COMPOSITES AND METHODS AND APPARATUS FOR FABRICATING SAME - In a method for fabricating a carbon nanotube (CNT) composite, an array of CNTs is provided. A CNT ribbon is pulled from the array and wound on a rotating mandrel. A polymer solution is applied to the ribbon to form a CNT composite laminate. The CNTs in the ribbon may be substantially aligned in a single direction. The ribbon may be attached to the mandrel such that the ribbon may be wound on the mandrel as the mandrel rotates. A CNT composite is provided that may include a polymer integrated with long, substantially straight CNTs that are highly aligned in a single direction. An apparatus for fabricating a CNT composite is provided that may include a rotatable mandrel and a spray gun. The spray gun may be configured for spraying a polymer solution on the CNT ribbon as the CNT ribbon is taken up on the rotating mandrel. | 11-08-2012 |
20120261999 | RECONFIGURABLE POWER SYSTEMS AND CONVERTERS - Reconfigurable power systems and converters and operating methods therefor are disclosed. Reconfigurable power systems may include a DC power source, an electrical energy storage device, an AC power grid connection, and a power converter configured to selectively couple two or more of the DC power source, the electrical energy storage device, and the AC power grid connection. | 10-18-2012 |
20120197575 | METHOD OF ABSORBANCE CORRECTION IN A SPECTROSCOPIC HEATING VALUE SENSOR - A method and apparatus for absorbance correction in a spectroscopic heating value sensor in which a reference light intensity measurement is made on a non-absorbing reference fluid, a light intensity measurement is made on a sample fluid, and a measured light absorbance of the sample fluid is determined. A corrective light intensity measurement at a non-absorbing wavelength of the sample fluid is made on the sample fluid from which an absorbance correction factor is determined. The absorbance correction factor is then applied to the measured light absorbance of the sample fluid to arrive at a true or accurate absorbance for the sample fluid. | 08-02-2012 |
20120196325 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR - Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 08-02-2012 |
20120175696 | MULTILAYER FLOATING GATE FIELD-EFFECT TRANSISTOR (FET) DEVICES AND RELATED METHODS - Multilayer floating gate field-effect transistor (FET) devices and related methods are provided. A multilayer floating gate FET device can include a first floating gate separated via a first dielectric layer from a channel of the device and a second floating gate separated via a second dielectric layer from the first floating gate. The second dielectric layer between the first floating gate and the second floating gate permits a redistribution of charge between the first and second floating gates from one of the floating gates to the other when under the influence of a first electrical field from a first voltage. In some embodiments, a redistribution of charge between the first and second floating gates with electrons being supplied through a channel to the first and second floating gates can occur when under the influence of a second electrical field from a second voltage that is greater than the first voltage. | 07-12-2012 |
20120149590 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CELL SURFACE PROTEIN HOMOLOGUES AND USES THEREFORE - Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed. | 06-14-2012 |
20120148841 | Method and Apparatus for Making an Improved High Surface Area Fiber - The present invention is directed to a high surface area fiber and method for making the same. The fiber includes a co-extruded internal fiber and an external sheath that is washed with a solvent to remove the dissolvable external sheath, the resulting fiber having a longitudinal axis and a cross-section, the cross-section having a middle region and projections extending from the middle region. | 06-14-2012 |
20120131710 | Pearlbush shrub named 'Blizzard' - ‘Blizzard’ is a new pearlbush plant particularly distinguished by its compact habit, smaller plant height and width, larger flower diameter, and larger genome size. | 05-24-2012 |
20120131709 | Weigela shrub named 'Sunset' - ‘Sunset’ is a new | 05-24-2012 |
20120118308 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 05-17-2012 |
20120117933 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 05-17-2012 |
20120077948 | Methods - The invention relates to a method of making a polypeptide comprising an orthogonal functional group, said orthogonal functional group being comprised by an aliphatic amino acid or amino acid derivative, said method comprising providing a host cell; providing a nucleic acid encoding the polypeptide of interest; providing a tRNA-tRNA synthetase pair orthogonal to said host cell; adding an amino acid or amino acid derivative comprising the orthogonal functional group of interest, wherein said amino acid or amino acid derivative is a substrate for said orthogonal tRNA synthetase, wherein said amino acid or amino acid derivative has an aliphatic carbon backbone; and incubating to allow incorporation of said amino acid or amino acid derivative into the polypeptide of interest via the orthogonal tRNA-tRNA synthetase pair. The invention also relates to certain amino acids, and to polypeptides comprising same. | 03-29-2012 |
20120075069 | REVERSIBLY DEFORMABLE AND MECHANICALLY TUNABLE FLUIDIC ANTENNAS - A method of manufacturing a fluidic structure is disclosed. A cavity that defines a shape of an element of the fluidic structure within a material is formed. The cavity is filled with liquid metal. The cavity is sealed. The fluidic structure behaves as an antenna. A fluidic antenna includes a material that defines a shape of the fluidic antenna by a cavity filled with liquid metal formed within the material, where the material further defines at least one mechanical property of the fluidic antenna. | 03-29-2012 |
20120034512 | LITHIUM ALLOY-CARBON COMPOSITE NANOFIBERS AND METHODS OF FABRICATION - A carbon/nanoparticle nanofiber includes a carbon base structure and a plurality of nanoparticles that include a lithium alloy or a lithium alloy precursor. One or more nanofibers may be formed into a nonwoven fabric. The fabric may be utilized as an electrode, such as for example in a battery. The carbon/nanoparticle composite nanofiber may be fabricated by forming a polymer/nanoparticle nanofiber, such as for example by a spinning technique, and carbonizing the polymer/nanoparticle nanofiber. | 02-09-2012 |
20120015020 | BIODEGRADABLE DRUG OR OTHER ACTIVE DELIVERY SYSTEM - A nonwoven fabric has been developed as a delivery system for drugs or other actives which includes biodegradable and biocompatible fibers with plant virus nanoparticles. The plant virus nanoparticles are pre-loaded with one or more actives. | 01-19-2012 |
20110294668 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator. | 12-01-2011 |
20110268911 | CONFORMAL COATING OF POLYMER FIBERS ON NONWOVEN SUBSTRATES - The present invention describes a novel process for the conformal coating of polymer fibers on nonwoven substrates. This process is based on the modification of polymer fiber surfaces by controlling the degree of etching and oxidation, which improves adhesion of initiators to the surface and facilitates subsequent conformal polymer grafting. The modified fiber surfaces render new functionalities to the surface, such as increasing hydrophilicity, attaching ligands or changing surface energy. The invention includes the modified polymer fibers produced by the process described herein. | 11-03-2011 |
20110183380 | POROUS, CARBOHYDRATE-BASED FOAM STRUCTURES AND ASSOCIATED METHODS - Porous, carbohydrate-based foam structures and associated methods are disclosed. According to an aspect, a method can include using a starch solution. The starch solution can be precipitated to form starch nanoparticles having a predefined void structure. | 07-28-2011 |
20110174322 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 07-21-2011 |
20110151053 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE - Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 06-23-2011 |
20110147764 | TRANSISTORS WITH A DIELECTRIC CHANNEL DEPLETION LAYER AND RELATED FABRICATION METHODS - A metal-insulator-semiconductor field-effect transistor (MISFET) includes a semiconductor layer with source and drain regions of a first conductivity type spaced apart therein. A channel region of a first conductivity type extends between the source and drain regions. A gate contact is on the channel region. A dielectric channel depletion layer is between the gate contact and the channel region. The dielectric channel depletion layer provides a net charge having the same polarity as the first conductivity type charge carriers, and which may deplete the first conductivity type charge carriers from an adjacent portion of the channel region when no voltage is applied to the gate contact. | 06-23-2011 |
20110081707 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR - Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 04-07-2011 |
20110079725 | APPARATUS AND METHOD TO ACHIEVE HIGH-RESOLUTION MICROSCOPY WITH NON-DIFFRACTING OR REFRACTING RADIATION - An imaging system employing a coded aperture mask having multiple pinholes is provided. The coded aperture mask is placed at a radiation source to pass the radiation through. The radiation impinges on, and passes through an object, which alters the radiation by absorption and/or scattering. Upon passing through the object, the radiation is detected at a detector plane to form an encoded image, which includes information on the absorption and/or scattering caused by the material and structural attributes of the object. The encoded image is decoded to provide a reconstructed image of the object. Because the coded aperture mask includes multiple pinholes, the radiation intensity is greater than a comparable system employing a single pinhole, thereby enabling a higher resolution. Further, the decoding of the encoded image can be performed to generate multiple images of the object at different distances from the detector plane. Methods and programs for operating the imaging system are also disclosed. | 04-07-2011 |
20110020900 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE - Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 01-27-2011 |
20110008292 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF - Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed. | 01-13-2011 |
20110005499 | FUEL INJECTION DEVICE FOR AN INTERNAL COMBUSTION ENGINE, AND ASSOCIATED METHOD - A fuel injection device and associated method are provided. An injector body defines an axial bore and has a nozzle exit extending into the combustion chamber. The injector body receives fuel within the bore and channels the fuel through the nozzle exit into the combustion chamber. A flow rate control member is movably disposed within the injector body bore and is actuatable by a first actuator to move with respect to and to interact with the nozzle exit to control a flow rate of the channeled fuel. A pintle member is movably disposed within a flow rate control member bore and is actuatable by a second actuator, independently of the flow rate control member, to move with respect to the flow rate control member and to interact with the nozzle exit to control a spray angle of the channeled fuel. The flow rate and spray angle are thereby independently controllable. | 01-13-2011 |
20100331202 | NANOTUBE STRUCTURES HAVING A SURFACTANT BILAYER INNER WALL COATING - Nanotubes and nanotube array structures comprise (a) a nanotube having an inner wall portion; and (b) a bilayer coating formed on the inner wall portions, with the bilayer coating comprised of surfactants. A secondary compound such as a protein, peptide or nucleic acid may be associated with the bilayer coating. The structures are useful for, among other things, affinity purification, catalysis, and as biochips. | 12-30-2010 |
20100322859 | ORAL DRUG COMPLIANCE MONITORING USING MAGNETIC-FIELD SENSORS - A method to measure compliance with a pharmaceutical regimen, by the steps of: (a) ingesting a dose of a medication ( | 12-23-2010 |
20100279349 | NUCLEIC ACIDS ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 11-04-2010 |
20100261983 | IMPLANTABLE DEVICES FOR DYNAMIC MONITORING OF PHYSIOLOGICAL AND BIOLOGICAL PROPERTIES OF TUMORS - Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo. | 10-14-2010 |
20100205703 | Cercis plant named 'Ruby Falls' - ‘Ruby Falls’ is a new and distinct variety of redbud that has the following unique combination of desirable features that are outstanding in a new variety.
| 08-12-2010 |
20100205702 | Cercis plant named 'Merlot' - ‘Merlot’ is a new and distinct variety of redbud that has the following unique combination of desirable features that are outstanding in a new variety.
| 08-12-2010 |
20100190703 | PEPTIDES SPECIFIC FOR HUMAN BLOOD OUTGROWTH ENDOTHELIAL CELLS - Provided herein are compositions and methods for binding outgrowth endothelial cells (OEC). The compositions consist of peptide ligands capable of binding OEC with high affinity and specificity. The compositions of the invention include peptides set forth in SEQ ID NO: 1-38 and variants and derivatives thereof. Compositions also include the nucleotide sequences encoding the peptides of the invention. The compositions find use in methods for the isolation of OEC and for the recruitment and retention of OEC to sites of therapeutic interest. Methods for the identification and isolation of other peptides capable of binding OEC are also provided. | 07-29-2010 |
20100037942 | COMPOSITIONS AND PROCESSES FOR FORMING PHOTOVOLTAIC DEVICES - Photovoltaic cells, including silicon solar cells, and methods and compositions for making such photovoltaic cells are provided. A silicon substrate having an n-type silicon layer is provided with a silicon nitride layer, a reactive metal in contact with said silicon nitride layer, and a non-reactive metal in contact with the reactive metal. This assembly is fired to form a low Shottky barrier height contact comprised of metal nitride, and optionally metal silicide, on the silicon substrate, and a conductive metal electrode in contact with said low Shottky barrier height contact. The reactive metal may be titanium, zirconium, hafnium, vanadium, niobium, and tantalum, and combinations thereof, and the non-reactive metal may be silver, tin, bismuth, lead, antimony, arsenic, indium, zinc, germanium, nickel, phosphorus, gold, cadmium, berrylium, and combinations thereof. | 02-18-2010 |
20100037941 | COMPOSITIONS AND PROCESSES FOR FORMING PHOTOVOLTAIC DEVICES - Methods and compositions for making photovoltaic devices are provided. A metal that is reactive with silicon is placed in contact with the n-type silicon layer of a silicon substrate. The silicon substrate and reactive metal are fired to form a silicide contact to the n-type silicon layer. A conductive metal electrode is placed in contact with the silicide contact. A silicon solar cell made by such methods is also provided. | 02-18-2010 |
20100028945 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING STRESS-RELATED PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 02-04-2010 |
20090270475 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES - Disclosure is provided for imidazole-phenyl derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. | 10-29-2009 |
20090263438 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES - Disclosure is provided for imidazole-triazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. | 10-22-2009 |
20090220969 | Identifying and quantifying small RNAs - One-step RT-PCR methods, compositions and kits for the detection and quantification of small RNAs in a sample are disclosed. The one-step RT-PCR approach involves polyadenylation of a small RNA followed by reverse transcription with a first primer containing a poly(T) sequence and at least two 3′ nucleotides complementary to the 3′ terminal end nucleotides of the small RNA, to produce a cDNA. This may be followed by PCR amplification using the same first primer as the revere primer and a second, forward primer in which a portion of its sequence is complementary to the 3′ terminal end of the cDNA. This may be then followed by detection and/or quantification of the amplified product. | 09-03-2009 |
20090205072 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 08-13-2009 |
20090198049 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS - A method of making a porphyrin is carried out by: (a) condensing (i) a 1,9-bis(N,N-)dialkylaminomethyl)dipyrromethane of Formula II: | 08-06-2009 |
20090183287 | Raspberry named 'Nantahala' - Linnaeus ‘Nantahala’ is a new and distinct variety of raspberry that has the following unique combination of desirable features that are outstanding in a new variety.
| 07-16-2009 |
20090178591 | Carbohydrate-gypsum composite - A carbohydrate-gypsum composite for use as a bonding agent in manufacturing gypsum construction materials is disclosed. The composite includes a carbohydrate substituted with sulfate moieties such as cellulose sulfate and a crystalline calcium sulfate dihydrate. The composite may be used in bonding paper cover sheets to a gypsum core to form a gypsum wallboard. Also disclosed are methods of making the composite and methods of making gypsum wallboard with the composite. | 07-16-2009 |
20090155913 | COMPOSITIONS COMPRISING PROMOTER SEQUENCES AND METHODS OF USE - Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided. | 06-18-2009 |
20090155213 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS AND USES THEREOF - NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided. | 06-18-2009 |
20090148673 | DEVICES CONTAINING CHIROPTICAL SWITCHING MATERIALS AND METHODS OF MAKING AND USING THE SAME - A polycarbodiimide polymer that is reversibly switchable between two distinct optical orientations is described. The polymer is useful in forming devices such as filters, storage media, actuators, and displays. Methods of making and using such polymers are also described. | 06-11-2009 |
20090143230 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator. | 06-04-2009 |
20090139990 | Portable Box for Carrying Items - A telescoping box includes a lid. The upper section of the box includes lids which are frictionally engagable therewith. The lids include speaker assemblies as part of each lid. The lids are removable and include connection points for audio signal sources such as MP3 players. | 06-04-2009 |
20090137795 | NEW ROUTE TO FORMYL-PORPHYRINS - A method of making a 5-formylporphyrin, comprises the steps of: condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin. Products and intermediates useful in such methods, along with methods of making such intermediates, are also described. | 05-28-2009 |
20090118356 | NEO-TANSHINLACTONE AND ANALOGS AS POTENT AND SELECTIVE ANTI-BREAST CANCER AGENTS - Compounds of Formulas I-II are described, | 05-07-2009 |
20090093021 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR - Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 04-09-2009 |
20090082576 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS - A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described. | 03-26-2009 |
20090069558 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS - A method of making chlorins comprises the steps of reacting (e.g. condensing) a dipyrrin western half intermediate with an eastern half intermediate to form a tetrahydrobilene, and then cyclizing the tetrahydrobilene to form a chlorin. Intermediates including tetrahydrobilenes useful in such reactions are also described. | 03-12-2009 |
20090055981 | Buddleja plant named 'Blue Chip' - ‘Blue Chip’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. Moderate vigor resulting in compact growth habit. 2. Ease of asexual propagation using softwood or semi-hardwood cuttings. 3. Spreading growth habit with multi-branched stems. 4. Male sterility, and low female fertility and reduced seed set, resulting in less opportunity for seedlings to originate in the landscape setting. 5. Blue flower color. | 02-26-2009 |
20090055980 | Buddleja plant named 'Miss Ruby' - ‘Miss Ruby’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. Moderate vigor resulting in compact growth habit. 2. Ease of asexual propagation using softwood or semi-hardwood cuttings. 3. Upright growth habit with flowers borne stiffly on upright shoots. 4. Low female fertility and reduced seed set, resulting in less opportunity for seedlings to originate in the landscape setting. 5. Bright pink flower color, unknown in any other butterfly bush variety. | 02-26-2009 |
20090023842 | PORPHYRIN AND CONDUCTIVE POLYMER COMPOSITIONS FOR USE IN SOLID-STATE ELECTRONIC DEVICES - Compositions comprising porphyrinic macrocycles and conjugated polymers such as polythiophene for use in organic electronic devices including solar cells are presented. Covalent linkage of a porphyrinic macrocycle to a polymer allows tuning of electronic and spectroscopic properties of conjugated polymers and can improve the heat stability of the system relative to a blended comparison. A composition comprising: at least one polymer comprising at least one porphyrinic macrocycle covalently linked to at least one conjugated polymer, wherein the porphyrinic macrocycle is metal-free is also presented. Inks can be formulated. Methods of making are provided. | 01-22-2009 |
20090005311 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF - Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed. | 01-01-2009 |
20090005261 | PURIFICATION OF IMMUNOGLOBULINS USING AFFINITY CHROMATOGRAPHY AND PEPTIDE LIGANDS - An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z-R | 01-01-2009 |
20080293133 | Textiles for use in bioreactors for expansion and maintenance of cells - A bioreactor for three-dimensional culture of liver cells is disclosed. The device is characterized by the use of textile vasculatures. A model and method for optimizing vasculature parameters is also disclosed. Liver acinar structure and physiological parameters are mimicked by sandwiching cells in the space between the two innermost woven textile hollow fibers, and creating radial flow of media from an outer compartment, through the cell mass compartment, and to an inner compartment. The theoretical optimum hydraulic permeability for the two innermost semi-permeable membranes is determined based on physiological hepatic sinusoidal blood flow and pressures. Experimental studies using a flow rate and pressure monitoring systems in conjunction with phase-contrast velocity-encoded MRI confirm theoretical results. Novel woven vascular tubes with optimum hydraulic permeability are disclosed for culturing hepatocytes in the multi-coaxial bioreactor. | 11-27-2008 |
20080269501 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces - A method of making a phosphono-substituted dipyrromethane comprises reacting an aldehyde or acetal having at least one phosphono group substituted thereon with pyrrole to produce a phosphono-substituted dipyrromethane; and wherein the phosphono is selected from the group consisting of dialkyl phosphono, diaryl phosphono, and dialkylaryl phosphono. Additional methods, intermediates and products are also described. | 10-30-2008 |
20080233615 | NUCLEIC ACID ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 09-25-2008 |
20080221319 | METHOD OF MAKING PORPHYRINS - A method of making a compound of Formula I: | 09-11-2008 |
20080216256 | Heterobifunctional reactive dyes comprising a cysteamine linking group - The presently disclosed subject matter relates to heterobifunctional reactive dyes comprising nitrogen-containing heterocycles substituted by both halogen and vinyl sulfone moieties. In particular, the presently disclosed subject matter relates to reactive dye compounds comprising two or more halo-substituted, nitrogen-containing heterocycles and an asymmetric bridging group, wherein at least one of the two or more halo-substituted, nitrogen-containing heterocycles further comprises a vinyl sulfone substituent. In some embodiments, the bridging group has a structure based on cysteamine or cysteine. The heterobifunctional reactive dyes have high substrate affinity and can be applied to substrates, such as cotton fibers, under low salt conditions and with reduced dye material waste. | 09-11-2008 |
20080202541 | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 08-28-2008 |