NIHON NOHYAKU CO., LTD. Patent applications |
Patent application number | Title | Published |
20150366845 | PHARMACEUTICAL COMPOSITION FOR DISEASES CAUSED BY PATHOGENIC MICROORGANISMS SUCH AS ASPERGILLUS - An object is to provide means for precisely treating pneumonia caused by intracellular parasite, protozoa, and/or fungus. A pharmaceutical composition for pneumonia, comprising a compound represented by the following general formula (1) as an active ingredient: (In the formula, R represents a halogen atom or a hydrogen atom, and X represents a halogen atom.) | 12-24-2015 |
20150297448 | RESIN CONTAINER FILLED WITH ANTIFUNGAL PHARMACEUTICAL COMPOSITION - Provided is a means for stably storing a pharmaceutical composition comprising a compound represented by the General Formula (I) below and/or a salt thereof, and for providing the pharmaceutical composition to the market. A resin container colored with a color having a hue (H) within the range of 7.0Y to 9.99Y or 7.0YR to 9.99YR, value (V) within the range of 1.0 to 6.0, and chroma (C) within the range of 0.5 to 7.5, according to Munsell color coordinates, is filled with a pharmaceutical composition comprising a compound represented by the General Formula (I) and/or a salt thereof, to store the pharmaceutical composition. | 10-22-2015 |
20150238606 | PHARMACEUTICAL COMPOSITION CONTAINING LULICONAZOLE - Means for controlling the formation amount of a formed amide form in relation to a pharmaceutical composition containing luliconazole is provided. Disclosed is a pharmaceutical composition containing 1) luliconazole and 2) one component or two or more components selected from carboxylic acid and derivative thereof, ketone, phosphoric acid and derivative thereof, local anesthetic, antihistamine, and POE-based nonionic surfactant; wherein a content of an amide derivative of luliconazole is not more than 0.2% by mass with respect to a charged amount of luliconazole after storage at 60° C. for 3 weeks or at 40° C. for 6 months. | 08-27-2015 |
20150183766 | CRYSTAL HAVING CRYSTAL HABITS AND PHARMACEUTICAL COMPOSITION OBTAINED BY PROCESSING THE CRYSTAL - An object is to provide means for improving the solubility of luliconazole. Disclosed is a crystal of luliconazole wherein the crystal has such a crystal habit that (021) plane is a specific crystal growth plane. | 07-02-2015 |
20140256687 | Agricultural and Horticultural Insecticide Composition and Method for Using the Same - Provided are an agricultural and horticultural insecticide composition comprising flubendiamide and dichlorvos and/or profenofos as active ingredients; and a method for using an agricultural and horticultural insecticide composition, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an agricultural and horticultural insecticide composition comprising flubendiamide and dichlorvos and/or profenofos as active ingredients. | 09-11-2014 |
20140213656 | Plant Growth Regulator and Method for Using the Same - Provided is a novel plant growth regulator. The disclosed plant growth regulator comprises flubendiamide as an active ingredient. | 07-31-2014 |
20140148493 | Agricultural and Horticultural Insecticide Composition and Method for Using the Same - Provided are an agricultural and horticultural insecticide composition comprising flubendiamide and tolfenpyrad as active ingredients; and a method for using an agricultural and horticultural insecticide composition, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an effective amount of an agricultural and horticultural insecticide composition comprising flubendiamide and tolfenpyrad as active ingredients. | 05-29-2014 |
20140142154 | ANTI-FUNGAL AGENT - An antifungal agent against a fungus of the genus | 05-22-2014 |
20140135221 | Desiccant and Defoliant Composition for Crops - Provided is a safer and higher-performance desiccant and defoliant composition. The disclosed desiccant and defoliant composition comprises two or more different kinds selected from the group consisting of protoporphyrinogen oxidase-inhibiting herbicides as active ingredients. | 05-15-2014 |
20140088157 | ENDOPARASITE CONTROL AGENT - Provided are an endoparasite control agent comprising a carboxamide derivative represented by the general formula (I): | 03-27-2014 |
20140080882 | CRYSTAL AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME CRYSTAL - An object is to provide means for improving the solubility of luliconazole. Disclosed is a crystal consisting of luliconazole and short chain alcohol having a number of carbon atom or atoms of 1 to 4. | 03-20-2014 |
20130267564 | BENZYLOXYPYRIMIDINE DERIVATIVE, AGRICULTURAL/ HORTICULTURAL INSECTICIDE COMPRISING DERIVATIVE AND METHOD FOR USING SAME - A benzyloxypyrimidine derivative represented by the formula (I) | 10-10-2013 |
20130231379 | AGENT FOR FUNGAL DERMATITIS - The invention provides a method for the treatment of fungal dermatitis. The treatment method involves administering an effective amount of luliconazole or a pharmaceutically acceptable salt thereof to a target in need of a treatment of fungal dermatitis. | 09-05-2013 |
20130096187 | PHARMACEUTICAL COMPOSITION FOR EXTERNAL USE - A pharmaceutical composition for external use, including: i) luliconazole represented by the following structural formula (1) and/or a salt thereof; and ii) crotamiton. | 04-18-2013 |
20130090365 | ANTIMYCOTIC PHARMACEUTICAL COMPOSITION - An object is to provide a medicament preparation which is excellent in the solubilization stability in relation to a compound represented by the general formula (1) during the storage in a low temperature region and a high temperature region. The present invention resides in a pharmaceutical composition comprising 1) the compound represented by the general formula (1) and/or a salt thereof and 2) a polyhydric alcohol derivative. General formula (1) (In the formula, R | 04-11-2013 |
20130011351 | ANTIMYCOTIC PHARMACEUTICAL COMPOSITION - In a pharmaceutical composition for external use containing a compound such as luliconazole and/or a salt thereof in an amount of 5% by mass or more, comprised is/are acetone, a polyoxyethylene alkyl (having 8 to 30 carbon atoms) ether, and/or a polyoxyethylene alkenyl (having 8 to 30 carbon atoms) ether. Provided is a preparation using a solvent other than crotamiton, propylene carbonate, and N-methyl-2-pyrrolidone as a solvent for solubilization and steric stabilization and having the following properties: 1) when a compound represented by the general formula (1) and/or a salt thereof has a stereoisomer, the amount of the stereoisomer of the compound and/or a salt thereof produced under a preservation condition of 60° C. for 3 weeks is 1% by mass or less with respect to the total mass of the compound and/or a salt thereof at the beginning of preservation; 2) the preparation is in a clear liquid state when preserved at a constant temperature of 20° C. immediately after manufacture; and 3) no crystal is deposited when the preparation is preserved at 5° C. for 2 weeks after manufacture. | 01-10-2013 |
20120329845 | PHARMACEUTICAL COMPOSITION - Disclosed is an antifungal agent for external use, which is characterized by containing a compound represented by the general formula (1) below, 50-95% by mass of an alcohol, and 0.1-35% by mass of water and/or an anionic surfactant. | 12-27-2012 |
20120149745 | ANTIMYCOTIC PHARMACEUTICAL COMPOSITION - A pharmaceutical composition which comprises 1) a compound represented by the following general formula (1) and/or a salt thereof; and 2) a ketone such as methyl ethyl ketone. Preferably, the compound represented by the following general formula (1) is luliconazole, where R | 06-14-2012 |
20120022120 | ANTIMYCOTIC PHARMACEUTICAL COMPOSITION - In a pharmaceutical composition for external use containing a compound such as luliconazole and/or a salt thereof, comprised are a higher alcohol which is in a liquid state at 1 atm and 25° C. and/or a diester of a dibasic acid, provided that a diester carbonate is excluded, and a polyoxyethylene alkyl ether and/or a polyoxyethylene alkenyl ether. Provided is a preparation using a solvent other than crotamiton, propylene carbonate, and N-methyl-2-pyrroridone as a solvent for solubilization and steric stabilization and having the following properties: 1) when a compound represented by the general formula (1) and/or a salt thereof has a stereoisomer, the amount of the stereoisomer of the compound and/or a salt thereof produced under a preservation condition of 60 degrees C. for 3 weeks is 1% by mass or less with respect to the total mass of the compound and/or a salt thereof at the beginning of preservation; 2) the preparation is in a clear liquid state when preserved at a constant temperature of 20° C. immediately after manufacture; and 3) no crystal is deposited when the preparation is preserved at 5° C. for 2 weeks after manufacture. | 01-26-2012 |
20120015997 | PHARMACEUTICAL COMPOSITION FOR EXTERNAL USE - Provided is a pharmaceutical composition for external use, including: (i) a compound represented by structural formula (2) and/or a salt thereof; and (ii) N-methyl-2-pyrrolidone. | 01-19-2012 |
20100249202 | AGENT FOR FUNGAL DERMATITIS - The invention relates to a therapeutic agent for fungal dermatitis, containing luliconazole or a pharmaceutically acceptable salt thereof as an active ingredient, and a composition for the treatment of fungal dermatitis, containing luliconazole or lanoconazole in a substantially dissolved state as an active ingredient. | 09-30-2010 |
20100204293 | PHARMACEUTICAL COMPOSITION - Disclosed is an antifungal agent for external use, which is characterized by containing a compound represented by the general formula (1) below, 50-95% by mass of an alcohol, and 0.1-35% by mass of water and/or an anionic surfactant. | 08-12-2010 |
20100173965 | ANTIFUNGAL COMPOSITION - Disclosed is a pharmaceutical composition for antifungal use, comprising: 1) one or more compounds selected from compounds represented by the general formula (1) below and physiologically acceptable salts thereof; 2) one or more compounds selected from polypropylene glycol, diesters of dibasic acids, triacetin, 2-ethyl-1,3-hexanediol, lauromacrogol, and polyoxyethylene-polyoxypropylene glycol; and 3) one or more compounds selected from glucono-δ-lactone, propylene glycol, glycerin, and lactic acid. General formula (1) (In the formula, X represents a halogen or hydrogen). | 07-08-2010 |
20100168200 | ANTIFUNGAL PHARMACEUTICAL COMPOSITION - Disclosed is an antifungal agent for external use, which is characterized by containing a compound represented by the general formula (1), 50 to 95 mass % of an alcohol such as ethanol, 0.1 to 35 mass % of water or the like, and 0.01 to 5 mass % of a cellulose thickening agent. X is a halogen or H. | 07-01-2010 |
20100048647 | NEMATICIDAL AGENT COMPOSITION AND METHOD OF USING THE SAME - The present invention provides a nematocide containing, as an active ingredient, an N-2-(pyridyl)ethylcarboxamide derivative represented by the formula (I): | 02-25-2010 |
20100009853 | PARASITIC PLANT CONTROL AGENT AND USE THEREOF - Parasitic plants parasitizing on crops can be controlled effectively, by providing an agent for controlling parasitic plants, which comprises tiadinil or the like as the active ingredient and a method for using an agent for controlling parasitic plants, which comprises treating a parasitized plant or soil with an effective amount of agent for controlling parasitic plants. As a result, the yield of crops can be recovered to the level of parasitism-free crops. Additionally, by inhibiting parasitism of parasitic plants strongly, development of the next generation can be inhibited so that the level of pollution with parasitic plants on agricultural land can be lowered with cultivating sensitive crops. | 01-14-2010 |
20090202602 | PHARMACEUTICAL COMPOSITION FOR APPLICATION TO NAIL - Since treatment effects of conventional external preparations were not satisfactory, it is aimed to provide a novel external preparation that is excellent in drug permeability to nail, capable of fully exhibiting effects of an antifungal drug, and effective for treatments of diseases such as nail mycosis and nail candidiasis, particularly, treatments for nail tinea. The external preparation of this invention is a pharmaceutical composition for nail characterized by containing an antifungal drug, alkylpyrrolidone or a derivative thereof, and a crosslinking hydrogel. | 08-13-2009 |
20090076109 | Pharmaceutical Composition for External Use - Provided is a pharmaceutical composition for external use, including: (i) a compound represented by the general structural formula (1) and/or a salt thereof; and (ii) N-methyl-2-pyrolidone: | 03-19-2009 |
20090030059 | PHARMACEUTICAL COMPOSITION FOR EXTERNAL USE - Provided is a pharmaceutical composition for external use, including: (i) luliconazole represented by the following structural formula (1) and/or a salt thereof; and (ii) α-hydroxycarboxylic acid and/or a salt thereof. | 01-29-2009 |
20080200457 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same - The present invention relates to 1,2,3 -thiadiazole compounds represented by formula (I): | 08-21-2008 |