NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES Patent applications |
Patent application number | Title | Published |
20160136458 | APPARATUS, METHOD, AND PROGRAM FOR PROCESSING MEDICAL IMAGE, AND RADIOTHERAPY APPARATUS - According to one embodiment, a medical image processing apparatus, includes: a first acquisition unit; a second acquisition unit; and a part-removed image generation unit, wherein the first acquisition unit is adapted to acquire a first radiograph that is a virtual radiograph generated to have a specified part or a predetermined part, among parts included in volume data indicative of a three-dimensional structure of an inside of a body of a patient, being emphasized, the second acquisition unit is adapted to acquire a second radiograph of the inside of the body of the patient, and the part-removed image generation unit is adapted to generate a part-removed image by removing the specified or predetermined part or parts other than the specified or predetermined part from the second radiograph with reference to the first radiograph. | 05-19-2016 |
20160029934 | LIQUID COLLECTING APPARATUS AND LIQUID COLLECTING METHOD - A suction drain device of a disclosed liquid collecting apparatus actively pushes and pulls blood. This achieves liquid collection at high speed even under decreased pressure depending on a physiological state of an animal. Moreover, the liquid collecting apparatus includes a First flow path and a second flow path having a given length. Accordingly, the flow path with a given length set in advance and thus a known volume allows collection of a given amount volume of blood without measuring a length and an amount of blood using a volume measuring device. Accordingly, no need of the measuring device allows reduction in size of the liquid collecting apparatus. Consequently, the liquid collecting apparatus can be installed adjacent to the animal to achieve reduction in dead volume. Moreover, blood is flown to a fourth flow path branched with a connecting terminal, and is also flown to the second flow path branched with a connecting terminal. The blood flown in the second flow path is collected at the highest priority. This obtains collection of fresh blood from a collecting source as a blood supply source. | 02-04-2016 |
20150299280 | MEDICAL TREATMENT USE OF CELL-MEMBRANE-PERMEABLE FIBROBLAST GROWTH FACTOR - The present invention relates to a chimeric protein formed by fusing a CPP containing a CPP-C domain in any of an FGF11, FGF12, FGF13, and FGF14 to an FGF1 or an FGF2, or DNA molecules that contain DNA sequences coding the FGF1 or the FGF2 and DNA sequences coding a CPP-C or vectors containing these DNA sequences. These chimeric protein, DNA molecules, or vectors can be used for a medicine or a method of treatment effective to a tissue on which an expression of an FGFR is low or becomes low due to any cause, a medicine or a method of treatment that can further dynamize bioactivity of the FGF1 or the FGF2 via the FGFR, or a medicine or a method of treatment that protects a stem cell against an influence from radiation exposure, a chemotherapy, or a similar treatment. | 10-22-2015 |
20150266937 | VACCINE FOR TREATMENT OF TAUTOPATHY - This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phospholylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly. | 09-24-2015 |
20140299784 | RADIOACTIVE SUBSTANCE DETECTION DEVICE, RADIATION SOURCE LOCATION VISIBILITY SYSTEM, AND RADIOACTIVE SUBSTANCE DETECTION METHOD - A radioactive substance detection device that detects a radioactive substance being present in a specified direction. A radiation detection element having a thickness that stops and detects a characteristic X-ray arriving from a radioactive substance being present in the specified direction that radiates both gamma rays and the characteristic X-rays, and allows the gamma ray arriving from the radioactive substance to pass through. A screening body having a thickness that screens out characteristic X-rays of radiation which arrives from directions other than the specified direction and allows gamma rays of radiation which arrives from directions other than the specified direction to pass through. | 10-09-2014 |
20140186261 | ANTI-TUMOR AGENT AND ANTI-TUMOR KIT - An anti-tumor agent comprising combination of a radioactive diacetyl-bis(N4-methylthiosemicarbazone) copper complex and a metabolic inhibitor. | 07-03-2014 |
20140186260 | RADIOPHARMACEUTICAL AND PHARMACEUTICAL KIT - A radiopharmaceutical comprising combination of a particular radioactive dithiosemicarbazone copper complex, and a chelating agent comprising a multidentate ligand having a maximum dentate number of 2 or more to 4 or less. | 07-03-2014 |
20140166890 | RESIN FOR SCINTILLATORS - A resin for scintillators having high radiation sensitivity, which is obtained without using a wavelength conversion agent. | 06-19-2014 |
20140135613 | PET/MRI DEVICE, PET DEVICE, AND IMAGE RECONSTRUCTION SYSTEM - A PET/MRI device includes an MRI device that has a measurement port, a PET detector that can be inserted into the measurement port, and a mechanism that can slide the PET detector into and out of the MRI measurement port. Thereby, the PET/MRI device allows MRI measurement during PET measurement. | 05-15-2014 |
20140061483 | COINCIDENCE DETERMINATION METHOD AND APPARATUS OF PET DEVICE - In a coincidence determination of a PET device, the PET device uses a scintillator of radioactive isotope containing background noise due to intrinsic radioactivity as a radiation detector. The PET device counts a pair of annihilation radiations that is assumed to occur from a same nuclide. The annihilation radiations are detected within a predetermined coincidence time window by a plurality of radiation detectors. The method includes determining a coincidence with a wide energy window that allows detecting the background noise due to intrinsic radioactivity as multiple coincidences; removing the multiple coincidences; and using an energy window narrower than the wide energy window to limit a coincidence event to a coincidence event in a photopeak from a positron nuclide only. | 03-06-2014 |
20140046180 | INCLINED PET DEVICE AND PET COMBINED DEVICE - An inclined PET device is provided in which the cut plane of a detector ring upon which a plurality of PET detectors are disposed is inclined so that it does not intersect perpendicularly with the long axis of a bed that carries a subject to be examined and in which an open space that passes through the bed in a direction perpendicular to the long axis thereof is formed, in order to enable access to the subject to be examined. The PET detectors are disposed and stacked in a direction parallel to the long axis of the bed. Thereby, the number of PET detectors is reduced and device cost is reduced, while the detector ring as well as the device can be miniaturized. At the same time, the open space that passes through the bed in a direction perpendicular to the long axis can be preserved. | 02-13-2014 |
20130241555 | PET-MRI APPARATUS - In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a magnet that is a seamless structure generates a static magnetic field in a bore having a cylindrical shape. First detectors and second detectors are each formed in a ring shape and detect gamma rays emitted from positron emitting radionuclides injected into a subject. The first detectors and the second detectors are disposed with a space therebetween in an axial direction of the bore so as to interpose the magnetic field center of the static magnetic field therebetween. | 09-19-2013 |
20130234710 | PET-MRI APPARATUS - In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a transmitting radio frequency coil applies a radio frequency magnetic field on a subject placed in a static magnetic field. A detector is formed in a ring shape, disposed on a side adjacent to an outer circumference of the transmitting radio frequency coil, includes at least two PET detectors disposed with a space therebetween in an axial direction of a bore so as to interpose the magnetic field center of the static magnetic field therebetween, and detects gamma rays emitted from positron emitting radionuclides injected into the subject. Radio frequency shields are each formed in an approximately cylindrical shape, disposed between the transmitting radio frequency coil and the detector, and shield the radio frequency magnetic field generated by the transmitting radio frequency coil. | 09-12-2013 |
20130211233 | INTEGRATED PET/MRI SCANNER - In the integrated PET/MRI scanner provided with an RF coil for MRI and a plurality of PET detectors in the measuring port of the MRI scanner, the PET detectors are disposed with spaces therebetween and at least the transmitting coil elements of the RF coil for MRI are disposed between adjacent PET detectors. Here, the PET detectors are disposed in the circumferential direction of the measuring port with spaces therebetween and the transmitting coil elements are disposed in the axial direction of the measuring port. Alternatively, at least some of the PET detectors are disposed in the axial direction of the measuring port with spaces therebetween and the transmitting coil elements are disposed between adjacent PET detectors. The PET detectors can be DOI-type detectors capable of detecting position in the depth direction. | 08-15-2013 |
20130189289 | VACCINE FOR TREATMENT OF TAUTOPATHY - This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phosphorylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly. | 07-25-2013 |
20130056638 | Three-dimensional radiation position detector and method of identifying sensed positions therein - A three-dimensional position-sensitive radiation detector is provided which has a three-dimensional array of photodetectors disposed on the surface of a scintillator block and which is capable of three-dimensionally identifying the position of light emission at which radiation has been detected within the detector. The three-dimensional position-sensitive radiation detector includes: a scintillator block including a central portion which restricts the direction of diffusion of light so as to direct the light in three axial directions and which has an optically discontinuous region, and an outer portion which is disposed on the outside of the central portion and which does not restrict the direction of diffusion of light; and photodetectors disposed on at least two outer circumferential surfaces of the scintillator block. The detector identifies three-dimensionally the position of light emission, thereby preventing deterioration in position discrimination performance even when inner scintillator elements are smaller than the photodetectors. | 03-07-2013 |
20130037722 | METHOD AND SYSTEM FOR IMAGING USING NUCLEAR MEDICINE IMAGING APPARATUS, NUCLEAR MEDICINE IMAGING SYSTEM, AND RADIATION THERAPY CONTROL SYSTEM - In imaging on the basis of list mode data of a list of radioactive count data detected by a nuclear medicine imaging apparatus for measuring radiation in a pulse mode, the processing from the measurement to imaging of radiation is accelerated substantially to the real time level by selecting the number of count data to be used for online imaging computations on the basis of the counting rate of radiation. | 02-14-2013 |
20130030287 | PROXIMITY IMAGING TYPE PET APPARATUS AND SYSTEM - Provided are a proximity imaging type PET apparatus and a system which include a part-specific PET scanner disposed in proximity to a specific part of a measurement target and a whole-body PET scanner which is capable of radiographing the whole body of the measurement target, the PET apparatus and system being capable of bringing PET detectors into close proximity to the specific part of the measurement target so as to ensure higher sensitivity and imaging a wide field of view. | 01-31-2013 |
20130020489 | COINCIDENCE DETERMINATION METHOD AND APPARATUS FOR PET DEVICE - For coincidence determination, a PET device that regards and counts a pair of annihilation radiations detected within a predetermined time as occurring from the same nuclide changes a coincidence time width according to a maximum detection time difference. This prevents the inclusion of extra noise data for improved image quality. | 01-24-2013 |
20130010108 | MEASURING SYSTEM - A boundary calculating unit is provided for determining boundaries between separated plasma and blood cell or air and plasma whose image is picked up by an image pickup unit. With such boundary calculating unit provided, the boundaries between the separated plasma and blood cell or air and plasma can be determined, and areas of the separated air, plasma, and blood cell can be determined accurately. Particularly, a straight line drawing unit is provided for drawing, on the image picked up, a plurality of straight lines parallel to grooves in a disk which performs plasma separation. The boundary calculating unit can easily determine the boundaries by determining the boundaries based on a profile of the plurality of straight lines drawn by the straight line drawing unit. | 01-10-2013 |
20130009064 | COINCIDENCE DETERMINATION METHOD AND APPARATUS OF PET DEVICE - In a coincidence determination processing of a PET device for regarding and counting a pair of annihilation radiations detected within a predetermined time as occurring from the same nuclide, a priority of a line of response to acquire is set and a true coincidence is extracted from multiple coincidences by using information on a detection time difference if a plurality of coincidences are detected with the predetermined time. Consequently, a true coincidence is extracted from multiple coincidences which have heretofore been discarded. This improves detection sensitivity at high radioactive concentration and contributes to an improved dynamic range. | 01-10-2013 |
20120305796 | PARTICLE BEAM IRRADIATION APPARATUS AND CONTROL METHOD OF THE PARTICLE BEAM IRRADIATION APPARATUS - Provided is a particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan with a simple configuration, while reducing degradation of a particle beam shape. The particle beam irradiation apparatus according to the present invention includes: a beam generation portion that generates a particle beam; a beam emission control portion that controls emission of the particle beam; a beam scanning portion that two-dimensionally scans the particle beam; a sensor portion including a plurality of first linear electrodes arranged in parallel in a first direction and a plurality of second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from a first signal output from each of the first linear electrodes and a second signal output from each of the second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose. | 12-06-2012 |
20120305790 | PARTICLE BEAM IRRADIATION APPARATUS AND CONTROL METHOD OF THE PARTICLE BEAM IRRADIATION APPARATUS - Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission. The particle beam irradiation apparatus according to the present invention includes: an emission control portion that controls emission and termination of a particle beam; a control portion that sequentially changes an irradiation position of the particle beam relative to an affected area; first and second dosimeters that measure dose rates of the particle beam directed to the affected area; and an abnormality determination portion that accumulates the dose rates output from the first and second dosimeters for each of predetermined determination periods to calculate first and second sectional dose measurement values and that performs second abnormality determination of determining that there is an abnormality and outputs an interlock signal for terminating the emission of the particle beam in at least one of a case in which the first sectional dose measurement value exceeds a predetermined first reference range and a case in which the second sectional dose measurement value exceeds a predetermined second reference range. | 12-06-2012 |
20120276531 | GENES FOR PROGNOSIS OF CANCER - To provide a novel method for determining the risk of lymph node metastasis of breast cancer uses as an index the difference in the expression levels of marker genes in at least one material selected from the group consisting of a breast tissue and a breast cell of a patient. The method includes measuring an expression level of a marker gene in at least one material selected from the group consisting of a breast tissue and a breast cell of a patient with breast cancer, and determining the risk of lymph node metastasis of breast cancer in the patient using the expression level of the marker gene as an index. | 11-01-2012 |
20120235046 | RADIATION DETECTION ELEMENT - Disclosed is a radiation detection element which can inexpensively be manufactured. The detection element including, as a main component, a base resin not containing any fluorescent substance at all is used for radiation measurement. | 09-20-2012 |
20120165651 | DETECTOR ROTATION TYPE RADIATION THERAPY AND IMAGING HYBRID DEVICE - An imaging device, or a PET device, opposed gamma camera type PET device, or open PET device in particular, that is combined with a radiation therapy device, in which detectors are rotated to reduce incidence of nuclear fragments on the detectors. For example, in an opposed gamma camera type PET device, beam irradiation and detector rotation can be synchronized to prevent the detectors from interfering with the treatment beam and reduce the incidence of nuclear fragments on the detectors. This makes it possible to reduce the incidence of nuclear fragments on the detectors without interfering with a treatment beam, thereby enabling measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or during irradiation. | 06-28-2012 |
20120161014 | MULTI-PURPOSE PET DEVICE - In an open PET device including a plurality of detector rings that are arranged apart in the direction of the body axis of a subject and having a physical open field of view area, at least one of the detector rings or another imaging device arranged in parallel is configured to be movable by simple device moving means in order to change the configuration of the PET device. This improves the versatility of the open PET device for easier introduction to facilities. | 06-28-2012 |
20120150018 | SHIELD TYPE RADIATION THERAPY AND IMAGING HYBRID DEVICE - A shielding structure against nuclear fragments (referred to as a shield) is operated according to ON and OFF of beam irradiation so as to reduce incidence of nuclear fragments on detectors during beam irradiation. This enables measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or even during irradiation. | 06-14-2012 |
20120150017 | OPEN PET/MRI HYBRID MACHINE - A PET/MRI hybrid machine that combines a PET device with an MRI device, includes: an open PET device that has a PET field of view at least part of which is an open space accessible from outside; and an open MRI device that has an MRI field of view at least part of which is an open space accessible from outside, and the open space of the PET field of view and the open space of the MRI field of view are allowed to overlap each other at least in part. This makes it possible to simultaneously measure and image the same open space accessible from outside by the PET device and the MRI device, thereby acquiring functional information and morphological information at the same time. | 06-14-2012 |
20120107854 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY - An N-alkylpiperidine methanethiol ester derivative represented by any one of the general formulae (1) to (4) or a salt thereof has been discovered. The N-alkylpiperidine methanethiol ester derivative or the salt thereof has specificity for acetylcholinesterase or butyrylcholinesterase and is useful as a reagent for measurement of cholinesterase activity by the Ellman method. | 05-03-2012 |
20110224534 | PET/MRI DEVICE, PET DEVICE, AND IMAGE RECONSTRUCTION SYSTEM - A PET/MRI device includes an MRI device that has a measurement port, a PET detector that can be inserted into the measurement port, and a mechanism that can slide the PET detector into and out of the MRI measurement port. Thereby, the PET/MRI device allows MRI measurement during PET measurement. | 09-15-2011 |
20110127435 | GAMMA RAY DETECTOR, RADIATION DIAGNOSTIC DEVICE, TOMOGRAPHY DEVICE, AND METHOD OF ANALYZING TOMOGRAPHY DEVICE - A gamma ray detector for detecting a gamma ray emitted from a target of measurement includes: an organic scintillator for detecting Compton electrons resulting from a gamma ray emitted from the target of measurement; an inorganic scintillator for detecting a Compton gamma ray; and photodetector modules for detecting light generation in the corresponding scintillators. Light generation signals from the organic and inorganic scintillators are synchronously measured, and a detection window of a gamma ray is generated. Thus, an inexpensive radiation diagnostic device of an ultra-high S/N ratio and low cost is provided. | 06-02-2011 |
20110121184 | DOI RADIATION DETECTOR - In a DOI radiation detector, scintillation crystals are arranged in three dimensions on a light receiving surface of a light receiving element, and a response of a crystal having detected a radiation ray can be identified on the light receiving surface. Thereby, a position at which the radiation ray is detected is determined in three dimensions. In this DOI radiation detector, regular triangular prism scintillation crystals are used, and response positions of the respective crystals are shifted for each set. This allows crystal identification without loss even with a structure such as a three-layer or six-layer structure hard to achieve by a quadrangular prism scintillation crystal. | 05-26-2011 |
20110101229 | DOI TYPE RADIATION DETECTOR - This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal. | 05-05-2011 |
20110092814 | COMBINED RADIATION THERAPY/PET APPARATUS - A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images. | 04-21-2011 |
20110084211 | DETECTOR-SHIFT TYPE COMBINED RADIATION THERAPY/PET APPARATUS - In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement. | 04-14-2011 |
20110031407 | OPEN-TYPE PET SCANNER - In an open-type PET scanner including a plurality of detector rings having multiple rings arrayed in the body axis direction, radiation measurement is performed while at least one detector ring is relatively moved with respect to a subject in the body axis direction, thereby dispersing simultaneous radiation in an open region to suppress a local reduction in sensitivity. The detector rings are optimized in constitution, moving direction and/or moving speed, thus making it possible to reduce the variation of distribution of sensitivity and expand a clearance in the open region and a field-of-view in the body axis direction. | 02-10-2011 |
20110024638 | PET SCANNER AND METHOD FOR DECIDING ARRANGEMENT OF DETECTORS - A PET scanner in which detector rings are arrayed in a multilayered manner so as to oppose each other in the body axis direction is provided. In the PET scanner, a predetermined number of detector units, each of which is made up of a predetermined number of detector rings, are arrayed so as to give each other a clearance, and a first ring set in which the clearance is less than or equal to a mean value of widths of two detector units forming each clearance and a second ring set constituted with a predetermined number of detector units are arrayed apart so as to give a clearance which is less than or equal to a mean value of the width of the first ring set and that of the second ring set, thereby imaging a field-of-view including the clearance and continuing in the body axis direction to an entire length of the first ring set and that of the second ring set. | 02-03-2011 |
20110024637 | OPEN-TYPE PET SCANNER - In an open-type PET scanner, detector rings arranged in a multilayered manner in an axial direction are at least partially opened and the thus opened part of the detector rings is at least partially included in a main focus region. Then, at least some of the detecting elements constituting the detector ring are disposed obliquely in the axial direction so that the main sensitivity direction thereof is turned closer to the main focus region, increasing the resolution in the main focus region. Thereby, it is possible to retain resolution in the body axis direction without using a high-resolution DOI detector and to reduce the price of the open-type PET scanner. | 02-03-2011 |
20110001049 | METHOD FOR DETECTING RADIATION, DEVICE THEREOF, AND POSITRON EMISSION TOMOGRAPHY SCANNER - A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy. | 01-06-2011 |
20100308225 | BETA RAY DETECTOR AND BETA RAY RECONSTRUCTION METHOD - Provided are a beta ray detector and a beta ray reconstruction method capable of achieving consistently high detection efficiency of beta rays in a wider energy region compared to that of a conventional beta ray detector while enhancing energy resolution. The beta ray detector comprises an absorber scintillator | 12-09-2010 |
20100301221 | GAMMA RAY DETECTOR AND GAMMA RAY RECONSTRUCTION METHOD - Provided are a gamma ray detector and a gamma ray reconstruction method which can be used in SPECT and PET and which combine and reconstruct the information on “Compton-scattered” gamma rays, thereby remarkably increasing gamma ray detection sensitivity, decreasing the amount of a radioactive substance given to a subject, and remarkably reducing the concern about the amount of radiation exposure. The gamma ray detector comprises an absorber scintillator | 12-02-2010 |
20100274512 | METHOD, DEVICE AND PROGRAM FOR ESTIMATING PARTICLE EMITTED FROM RADIOISOTOPE SOURCE, METHOD FOR ESTIMATING RADIATION DETECTOR, METHOD AND DEVICE FOR CALIBRATING RADIATION DETECTOR, AND RADIOISOTOPE SOURCE - When an energy of a particle emitted from a radioisotope source is obtained by a detector, a histogram obtained from a relationship between a difference ΔE between an energy of a particle emitted outside the radioisotope source and an initial energy which the particle possesses at the time of generation and a count is treated as being asymmetric, and an energy distribution (L | 10-28-2010 |
20100237239 | Ion Beam Detector - In order to attain an object to realize an ion beam capable of (i) immediately determining energy of the ion beam to be generated, and (ii) measuring an ion beam in real time while carrying out laser irradiation, an ion beam detector ( | 09-23-2010 |
20100133445 | ION BEAM CONTROL APPARATUS AND METHOD - Provided are an ion beam control apparatus and a control method for controlling an ion beam energy expansion level and an ion beam size in a radial direction. An ion beam control apparatus Sa is provided with an ion beam generating unit | 06-03-2010 |
20100128956 | PET SCANNER AND IMAGE RECONSTRUCTION METHOD THEREOF - A plurality of detector rings in which detectors arranged densely or spatially in a ring shape or in a polygonal shape are arranged, with an open space kept in the body axis direction, coincidences are measured for some of or all of detector pairs connecting the detector rings apart from the open space to perform three-dimensional image reconstruction, thereby imaging the open space between the detector rings as a tomographic image. Therefore, the open space is secured, with the deteriorated quality of an image suppressed, thus making it possible to easily gain access to a patient under PET scanning from outside a gantry and also provide irradiation of particle beams for cancer treatment as well as X-ray CT scanning. | 05-27-2010 |
20100111838 | BRAIN-LOCALIZING POLYPEPTIDES COMPRISING A MULTIVALENT BINDING MOIETY AND IMPROVED METABOLIC STABILITY - Brain-localizing polypeptides carrying a reactive group for linking to a molecule that does not have brain-localizing activity were successfully produced by introducing at least two lysine residues into cyclized polypeptides having a brain-localizing motif sequence. These polypeptides have improved metabolic stability compared to conventional brain-localizing polypeptides, and can efficiently translocate desired molecules into the brain. | 05-06-2010 |
20100099976 | GAMMA- RAY DETECTOR AND PET APPARATUS USING THE SAME - A medium area (S) filled with liquid xenon ( | 04-22-2010 |
20100048512 | RADIATION PROTECTION DRUG CONTAINING TOCOPHEROL OR TOCOTRIENOL COMPOUND ESTER DERIVATIVE AS ACTIVE INGREDIENT - Administration of either a tocopherol represented by the general formula (1) or a tocotrienol compound ester derivative before or after exposure to radiation is effective in preventing or treating health disorders caused by the radiation exposure. | 02-25-2010 |
20100046818 | IMAGE RECONSTRUCTION METHOD FOR TOMOGRAPHY SCANNER, FAILURE DIAGNOSIS METHOD, TOMOGRAPHY SCANNER AND MANAGEMENT PROGRAM FOR SYSTEM MATRIX - In a case where an error is included in measurement data corresponding to one or a plurality of detecting elements in a tomography scanner, a system matrix to be calculated or referenced on image reconstruction calculation is corrected in accordance with the error. Thus, even when an error such as a defect or a fault occurs in a detector, influence of the error is eliminated, thereby reducing an artifact generated in an image. At that time, positional information of the detecting elements including the error and information on the degree of the error are stored in a storage device and referenced inside image reconstruction software, thus making it possible to correct the system matrix in accordance with the error. | 02-25-2010 |
20100032574 | RADIATION DETECTING METHOD UTILIZING ENERGY INFORMATION AND POSITIONAL INFORMATION AND EQUIPMENT THEREOF - Upon detection of radiation by using a (three-dimensional) detector capable of distinguishing a detection position in a depth direction and energy, an energy window for distinguishing between a signal and noise is changed depending on the detection position in the depth direction, thus making it possible to obtain scattering components inside the detector. Alternatively, a weight is given to a detection event depending on the detection position in the depth direction and energy information to obtain scattering components inside the detector. Thereby, scattering components inside the detector can be obtained to increase the sensitivity of the detector. In this case, different detecting elements can be used depending on the detection position in the depth direction. | 02-11-2010 |
20100028871 | Light-inducible and rhythmically expressed genes and method for screening substances that affect an internal clock system - A method for screening a substance that affect an internal clock system in an organism, comprising the detection of the expression level of a gene exhibiting a light-inducible and rhythmic expression in a circadian manner, which is typically expressed in the suprachiasmatic nucleus of mammalian, such as for example, Dusp4, Snk, Slc39a6 or Nnat. | 02-04-2010 |
20090311753 | Method for amplifying genomic DNA - A method for amplifying genomic DNA is provided. The method comprises the steps of: (1) incubating a cell-containing agarose solution at a pH of 9 to 12 and a temperature of 45 to 80° C. to produce a genomic DNA-dispersed agarose solution wherein 0.002 to 1 copies/5 microliter of single-stranded genomic DNA is dispersed; (2) solidifying the genomic DNA-dispersed agarose solution to produce a genomic DNA-dispersed agarose gel and neutralizing a pH of the gel; and (3) adding a DNA polymerase with strand displacement activity, primer and dNTP to the genomic DNA-dispersed agarose gel and incubating the gel at a temperature of 0 to 60° C. to amplify the genomic DNA. | 12-17-2009 |
20090294669 | SURFACE CONTAMINATION EXAMINING DEVICE AND METHOD - A surface contamination examining device includes a radiation detector | 12-03-2009 |
20090271143 | RADIATION MEASURING DEVICE AND DATA PROCESSING METHOD - A radiation measuring device capable of identifying the incident direction of a radiation ray and energy (segmentation) The directivity characteristics of a plurality of detectors are different from each other. A plurality of energy segmentations are set respectively for a plurality of spectra corresponding to a plurality of detectors, and actual measurement ratio information (a plurality of actual measurement counting ratios) expressing the mutual ratio between integrated counting values for each energy segmentation is computed. The actual measurement ratio information is checked against a plurality of response functions, and, when the compatibility relation between specific actual measurement ratio information and specific theoretical ratio information is found, the incident direction of a radiation ray and an energy segmentation are identified based on that relation. | 10-29-2009 |
20090261760 | H-MODE DRIFT-TUBE LINAC AND DESIGN METHOD THEREFOR - A linearity of a voltage change to a tuner insertion amount is verified for at least one of a plurality of tuners. Based on the voltage change linearity, individual voltage change data corresponding to respective insertion amounts are calculated for each of the plurality of tuners through a proportional calculation. A combination of auto-tuners and a combination of respective insertion amounts of the auto-tuners are determined using the individual voltage change data, and an adequacy of the determined combinations is verified through a direct three-dimensional electromagnetic field calculation. The combinations are determined on a condition that, when the individual voltage change data of nominated tuners are added together, respective voltage changes attributed to the nominated tuners are cancelled out to allow an entire voltage distribution to have substantially no change. | 10-22-2009 |
20090252296 | MULTI-COLOR X-RAY GENERATOR - A multi-color X-ray generator includes an electron beam generator | 10-08-2009 |
20090234162 | Radioactive Halogen-Labeled Phenyloxyaniline Derivatives - A radioactive halogen-labeled phenyoxyaniline derivative represented by the following formula: wherein R | 09-17-2009 |
20090159804 | Positron emission tomography scanner and radiation detector - A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference. | 06-25-2009 |
20090069592 | METHOD FOR SYNTHESIZING RADIOACTIVE LIGAND HAVING 18F-LABELED FLUOROBENZENE RING - A phenyl tin compound is synthesized by using a derivative having various functional groups and a bromo- or iodo-benzene ring as a labeling material of a radioactive ligand. On the other hand, a novel hydroxytosyl iodobenzene compound having an electron-donating group is obtained by oxidizing iodobenzene having one or more electron-donating groups and reacting it with tosylic acid. Then, a diphenyliodonium salt which is a labeling precursor is synthesized by reacting the resulting compound with various phenyl tin compounds. Finally, a | 03-12-2009 |
20090067570 | Computed tomography method and apparatus for a dynamic image of a moving site - When a repeatedly periodically moving site of a to-be-examined subject in a gantry is subjected to computed tomography and is reconstructed, the gantry is rotated in synchronization with the movement of the periodically moving site, and a dynamic image showing a transient phenomenon is obtained in which the periodic movement of the moving site has been stopped. As a result, the flow of a contrast agent or the like can be observed in a state of stopping the movement of an internal organ that moves repeatedly periodically. | 03-12-2009 |
20090052625 | DEVICE FOR SWITCHING/GENERATING X-RAYS FOR DIAGNOSIS AND CURING - There is disclosed a device including: an electron beam generation device | 02-26-2009 |
20090051937 | Device and method for measuring profiles of electron beam and laser beam - A device for measuring profiles of an electron beam and a laser beam is provided with a profile measuring device | 02-26-2009 |
20090022379 | Method for Quantifying Organ Motion, Apparatus Therefor, Method for Estimating Organ Position, Apparatus Therefor, Method for Irradiating Radiation, Apparatus Therefor, and Apparatus for Detecting Abnormal Organ - A plurality of CT images of an organ ( | 01-22-2009 |
20090011423 | GENES FOR PROGNOSIS OF CANCER - To provide a novel method for determining the risk of lymph node metastasis of breast cancer uses as an index the difference in the expression levels of marker genes between metastatic breast cancer tissue (or cell) and non-metastatic breast cancer tissue (or cell). The method involves ( | 01-08-2009 |
20080272305 | Radiation Detected Value Forecasting Method and Forecast Responsive Radiation Detector - In a radiation detector, a response is approximated as a primary delay system, and when a time constant T indicating the characteristic of the response is known, a final response value N | 11-06-2008 |