Molecular Devices, Inc. Patent applications |
Patent application number | Title | Published |
20120313010 | System and Method for Automatically Determining Optimal Excitation and Emission Wavelengths of a Fluorophore - A system for performing spectrofluorometry of a fluorophore sample is provided. The system includes an input module that receives user input corresponding to spectrofluorometer settings. A control module transmits control signals for controlling the spectrofluorometer during respective wavelength scans of a fluorophore sample and a blank sample. The control signals provide for automatic execution of the wavelength scans over an excitation wavelength range and an emission wavelength range. A signal-to-background determination module automatically determines multiple signal-to-background ratios based on fluorescence measurements of the fluorophore sample and the blank sample received from the spectrofluorometer. A signal-to-background analysis module automatically determines the maximum signal-to-background ratio from the multiple signal-to-background ratios. | 12-13-2012 |
20120299927 | SYSTEM AND METHOD FOR DISPLAYING PARAMETER INDEPENDENCE IN A DATA ANALYSIS SYSTEM - A system for performing a data analysis is provided. The system includes a curve fit module that determines a curve fit function for a data set. A parameter dependence determination module determines a dependence value for a parameter of the curve fit function. A parameter independence determination module determines an independence value for the parameter of the curve fit function based on the dependence value for the parameter. A graphical indicator generation module generates a graphical indicator for the parameter. The graphical indicator corresponds to the independence value for the parameter. | 11-29-2012 |
20110251102 | HIGH THROUGHPUT SCREENING OF ION CHANNELS - Multi-well plates having contoured well designs allow multi-stage high throughput parallel assaying of ion channels or ion transporters. A well of a multi-well plate has a bottom region that is sized and shaped to simultaneous accommodate a sensing electrode and a pipette for delivering, e.g., test compounds, wash fluid, and optionally ligands. Such multi-well plates may be coupled with an instrument having a pipette head and an electrode plate. Such arrangement facilitates fluidic contact between cells and fluids provided via a pipette. It also facilitates washing of wells with buffers or other wash solutions to allow serial exposure of test cells to various reagents or other stimuli. Generally, the design allows control and test experiments to be performed on the same cell (or cells) in a single well. | 10-13-2011 |
20110109946 | VIBRATION CONTROL IN SCANNERS - A scanning apparatus ( | 05-12-2011 |
20110090563 | UNIFORMITY IN SLIDE SCANNING - A sample slide stage includes at least four fixed members that are arranged at, or about at, a focal plane of the slide stage, and are configured to receive a slide; and a plurality of compression members that apply a controlled force to compress a slide towards the fixed members at the focal plane, whereby a surface of a non-planar slide in the sample stage is deformed towards the focal plane. Methods of deforming non-planar slides towards a focal plane include inserting a non-planar slide into a sample slide stage that has at least four fixed members arranged at or about at a focal plane; and applying a controlled force to compress the non-planar slide to the fixed members at the focal plane, whereby a surface of the non-planar slide is deformed towards the focal plane. | 04-21-2011 |
20100259805 | METHODS AND SYSTEMS FOR REDUCING SCANNER IMAGE DISTORTION - A scanning apparatus includes a sample stage that faces an optical scanning head or stage at a scanning plane; a first actuator that translates the sample stage or the optical stage along a first axis that is substantially parallel to the scanning plane; a sensor that senses the deviation from the first axis; and a controller coupled to the first actuator, the sensor, and the optical stage. The controller is programmed to operate the first actuator and the optical stage to acquire a scan of a sample at the sample stage; and modify the scan to compensate for a deviation from the first axis in translation of the sample stage or the optical stage along the first axis by the first actuator. Also included are methods of modifying scans to compensate for translation deviations. | 10-14-2010 |