GIRINDUS AMERICA, INC. Patent applications |
Patent application number | Title | Published |
20140179875 | SULFURIZATION REAGENTS ON SOLID SUPPORTS - Described herein are novel solid-supported sulfurization reagents having the general structure: (I) wherein (P) is a polymer; X is a linker; R | 06-26-2014 |
20130116450 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES - A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained. | 05-09-2013 |
20130096291 | New Method of Using N-Thio Compounds for Oligonucleotide Synthesis - A method for synthesizing an oligonucleotide which comprises using a sulfurizing agent of general formula (I) for sulfurizing at least one phosphorus internucleotide linkage of a precursor of the oligonucleotide, wherein R is an aryl group or a heteroaryl group, which is bonded to the S-atom through an annular carbon atom; and R | 04-18-2013 |
20120071640 | Sulfurizing reagents and their use for oligonucleotides synthesis - An oligonucleotide which comprises at least one internucleotide linkage comprising a P—S—R bond and at least two nucleosides, wherein R corresponds to the formula (I) | 03-22-2012 |
20120004427 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES - A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained. | 01-05-2012 |
20110087014 | Process for the manufacture of oligonucleotides - A process for manufacturing an oligonucleotide which comprises removing β-eliminating phosphorus-protecting groups, in particular β-cyanoethyl protective groups from a protected oligonucleotide, wherein said removing comprises contacting the protected oligonucleotide with an amine solution in a solvent which preferably does not consist of pyridine, wherein the conjugate acid of the amine has preferably a pKa of greater than 11.5, and wherein the concentration of the amine in the solution is less than 0.5 mole/liters. | 04-14-2011 |
20100069653 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES - A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained. | 03-18-2010 |