FRESENIUS KABI DEUTSCHLAND GMBH Patent applications |
Patent application number | Title | Published |
20160044946 | COMPOSITIONS FOR USE IN NUTRITION OF DYSPHAGIA PATIENTS - Dysphagia is a common health problem, the term describing a range of mechanical disorders that affect the safety, efficiency, or quality of eating and drinking. In dysphagia, every swallowing attempt bears the danger of choking and aspiration of liquids or food particles into the lung. Generally, when patients experience difficulties in swallowing, food thickeners are used to comply with clinically required levels of viscosity of liquid/semisolid products for use in nutrition for such patients. Herein, food thickening compositions as well as their use and applications are disclosed. | 02-18-2016 |
20150273133 | APPLICATION ARRANGEMENT WITH A MEDICINAL SUBSTANCE FLUID - An application arrangement for a medicinal substance fluid includes an application syringe with a plastic container, wherein the plastic container is filled with an oxygen-sensitive medicinal substance fluid and an oxygen-tight cover which surrounds the application syringe in oxygen-tight manner. | 10-01-2015 |
20150217104 | CONNECTOR FOR PRODUCING A FLUID CONNECTION TO A SECOND CONNECTOR, CONNECTOR SYSTEM, AND METHOD FOR PRODUCING A FLUID CONNECTION - A connector for producing a fluid connection to a second connector, wherein the connector can, in at least one connector area, form a weakened structure, in order to be able to break open the connector in the connector area and in this way produce a fluid connection to the second connector. A partial area of the connector area is designed in such a way that the weakened structure in the partial area can be generated by covering or spraying the connector area with a medium. | 08-06-2015 |
20150105471 | PARACETAMOL FOR PARENTERAL ADMINISTRATION - The invention relates to an aqueous pharmaceutical composition, preferably an infusion solution, for parenteral administration which contains paracetamol and has an electrical conductivity of not more than 200 μS cm | 04-16-2015 |
20150034713 | BAR CODE READER FOR A MEDICAL DEVICE - A bar code reader (2) for a medical device (3) is configured to be attached to a central communication device (1) to which at least one medical device (3) is attachable. The bar code reader (2) comprises a bar code scanning device (21) for scanning a bar code (4), a processing device (22) for decoding the scanned bar code (4) to obtain decoded bar code data which is contained in the scanned bar code (4), and a connection line (24) for outputting the decoded bar code data to the central communication device (1). The processing device (22) herein is operative to decode bar codes (4) of different bar code types. Furthermore, the processing device (22) is configured to map the decoded bar code data to a predefined standardized output format and to output the decoded bar code data in the predefined standardized output format via the connection line (24). Thus, a bar code reader and a method for processing a bar code scanned by a bar code reader are provided which are capable of reading and interpreting bar codes of a variety of different types and allow for outputting the data contained in a bar code in a manner such that a central communication device to which the bar code reader is attached may easily interpret the data. | 02-05-2015 |
20140271548 | DEVICE AND METHOD FOR PREPARING A FLUID COMPOSITION FOR COMPLETE OR SUPPLEMENTAL ENTERAL NUTRITION - The invention relates to a device for preparing a fluid composition for complete or supplemental enteral nutrition, comprising a liquid feeding device, an ingredient feeding device and a mixing device for mixing a liquid fed from the liquid feeding device and at least one ingredient fed from the ingredient feeding device, the mixing device comprising a mixer and a mixing container in which the liquid and the at least one ingredient are mixed by the mixer. The device is operable to move the mixing container relative to the mixer during mixing of the liquid and the at least one ingredient of the fluid composition to be prepared. Also provided is a method for preparing a fluid composition for complete or supplemental enteral nutrition using the device. | 09-18-2014 |
20140234144 | TUBE PUMP, TUBE CLAMP, PERFUSION SET AND SYSTEM COMPRISING A TUBE PUMP AND A TUBE CLAMP - The invention concerns a tube pump comprising a cradle ( | 08-21-2014 |
20140205673 | PRODUCT FOR PARENTERAL NUTRITION OF OBESE INTENSIVE-CARE PATIENTS - The invention relates to a high-amino-acid, low-lipid and low-carbohydrate parenteral nutrition solution for administration to obese intensive-care patients, and to a three-chamber pouch which comprises the amino acid component, the carbohydrate component and the lipid component of the parenteral nutrition solution separately in three different chambers. | 07-24-2014 |
20140093863 | TRANSPARENT COOLING GEL - For cooling organs and tissues in transplantation medicine, only ice preparations are used so far which are not soft like a gel and are brought to the necessary degree of comminution by mechanically comminuting frozen, sterile, pyrogen-free isotonic infusion solutions, such as 5% glucose or 0.9% saline, with great effort. The lack of gel-like consistency of the preparations and the expensive production process are very disadvantageous. | 04-03-2014 |
20140088298 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxy-yalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS′(-L-M) | 03-27-2014 |
20140073779 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS′(-L-M) | 03-13-2014 |
20140073778 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to hydroxyalkyl starch conjugates, a method for preparing the same, the hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent and the cytotoxic agent comprising at least one tertiary hydroxyl group, wherein the hydroxyalkyl starch is linked via said tertiary hydroxyl group to the cytotoxic agent. The conjugates according to the present invention have a structure according to the following formula HAS′(-L-M) | 03-13-2014 |
20140073602 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES - The present invention relates to nitric oxide delivering hydroxyalkyl starch derivatives, methods of preparing the same, and specific uses of these hydroxyalkyl starch derivatives. | 03-13-2014 |
20130230898 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION - The invention relates to a method for the preparation of a hydroxyalkyl starch derivative which comprises reacting hydroxyalkyl starch (HAS) via the optionally oxidised reducing end of the HAS with the amino group M of a crosslinking compound which, apart from the amino group, comprises a specifically protected carbonyl group, namely an acetal group or a ketal group. | 09-05-2013 |
20130226103 | Port cannula for the puncturing of port catheters - A port cannula for puncturing implantable or implanted port catheters includes a cannula tube with a ground surface, which is formed from a ground cut inclined with respect to a center axis of the cannula tube by a ground-cut angle and from two facet cuts lying at an angle to each other, and of a cannula tip which is provided by the ground surface and which is oriented via a first bend in the direction of the center axis of the cannula tube. The ground cut and the facet cut are adapted to each other in such a way that, on the one hand, during puncturing, a bending of the cannula is least reduced and, on the other hand, the pain caused to the patient is kept within an acceptable range. | 08-29-2013 |
20130211060 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxy-yalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS′(-L-M) | 08-15-2013 |
20130197212 | Hydroxyalkyl starch for the treatment of head and neck cancers by reduction of tumor growth rates - The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of head and neck cancer, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted. | 08-01-2013 |
20130197211 | Hydroxyalkyl starch for the treatment of cancers by reduction of tumor growth rates - The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of cancer, tumor or tumor associated diseases, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted. | 08-01-2013 |
20130197087 | COMPOSITION COMPRISING A COMBINATION OF DHA AND EPA FOR ADMINISTRATION PRIOR TO COMMENCEMENT OF CHEMOTHERAPY - The invention relates to a composition comprising a combination of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The composition can be used for enhancing the activity of chemotherapy or radiotherapy and/or in the prevention or reduction of side effects caused by the chemotherapy or radiotherapy in a patient ill with cancer, the composition being intended for administration to the patient prior to the commencement of a cycle of chemotherapy or radiotherapy. | 08-01-2013 |
20130196949 | Hydroxyalkyl starch in combination with cytostatica for the treatment of cancers by reduction of tumor growth rates - The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of cancer, tumor or tumor associated diseases, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted. | 08-01-2013 |
20130184455 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS′(-L-M) | 07-18-2013 |
20130184454 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to hydroxyalkyl starch conjugates, a method for preparing the same, the hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent and the cytotoxic agent comprising at least one tertiary hydroxyl group, wherein the hydroxyalkyl starch is linked via said tertiary hydroxyl group to the cytotoxic agent. The conjugates according to the present invention have a structure according to the following formula HAS′(-L-M) | 07-18-2013 |
20130184237 | NITRIC OXIDE DELIVERING HYDROXYALKYL STARCH DERIVATIVES - The present invention relates to nitric oxide delivering hydroxyalkyl starch derivatives, methods of preparing the same, and specific uses of these hydroxyalkyl starch derivatives. | 07-18-2013 |
20130178437 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION - The present invention relates to hydroxyalkyl starch (HAS) conjugates and to a method for preparing the hydroxyalkyl starch (HAS) conjugates, the hydroxyalkyl starch (HAS) conjugates comprising a hydroxyalkyl starch derivative and a cytotoxic agent, said conjugate having a structure according the following formula HAS′(-M) | 07-11-2013 |
20130153048 | METHOD AND DEVICE FOR THE STERILE CONNECTION OF PIPES - A method for the sterile connection of pipes, consisting of: providing a first and a second pipe; a separating area of the first and second pipes is heated; both pipes are mechanically separated by exerting traction and/or shear force onto the pipes so that both pipes are respectively separated in the heated separating area; after the pipes are separated, a mechanical contact between the end of the first pipe section of the first pipe formed by the separation of the first pipe is established with the end of the first pipe section of the second pipe, formed by the separation of the second pipe, and mechanical contact is established such that the ends of the pipe sections still have, following heating when they come into mechanical contact with each other, a temperature such that they form a material fit connection without additional heating after separation. | 06-20-2013 |
20130144248 | DEVICE TO INTRODUCE OR REMOVE A FLUID INTO OR OUT OF A CONTAINER - The invention relates to a device for feeding a liquid into or removing a liquid from a receptacle, said device having a spike ( | 06-06-2013 |
20130053812 | CLAMP AND CLAMPING SYSTEM AND USE THEREOF - A clamp for receiving cylindrical objects, comprising a main body, which on two opposite sides has connecting elements that are matched to one another for detachably connecting similar clamps, and a receiving region, which is designed in a substantially ring segment shape and has a receiving opening for connecting a cylindrical object to the main body in a detachable locking manner, said opening extending over less than 180° of the receiving region, and the inside diameter (D) of the receiving region being 32 mm, 17 mm to 24 mm, or 10 mm. | 02-28-2013 |
20130037509 | CLOSURE CAP FOR A RECEPTACLE FOR RECEIVING MEDICAL LIQUIDS, AND RECEPTACLE - The invention relates to a closure cap for a receptacle for receiving medical liquids and to a receptacle for medical liquids which has such a closure cap. | 02-14-2013 |
20130020226 | Product for parenteral nutrition of obese intensive-care patients - The invention relates to a high-amino-acid, low-lipid and low-carbohydrate parenteral nutrition solution for administration to obese intensive-care patients, and to a three-chamber pouch which comprises the amino acid component, the carbohydrate component and the lipid component of the parenteral nutrition solution separately in three different chambers. | 01-24-2013 |
20130011284 | PUMP MODULE, PUMP BASE MODULE AND PUMP SYSTEM - A module, a base module and a system which comprises a module and a base module includes a pump channel and a valve unit which is connected with the pump channel wherein a fluid can be pumped through the pump channel and the valve unit, wherein a first wall section of the valve unit is flexible. The pump module has a movable valve body arranged in the valve unit, wherein the valve body can occupy an idle position in which the valve body closes the valve unit to prevent fluid from passing through. The valve body can occupy an operating position in which the valve body allows the fluid to flow through the valve unit and in which the valve body can be put in operating position through a deformation of the first wall section of the valve bodies so that the fluid can flow through the valve unit. | 01-10-2013 |
20130008561 | CONNECTOR FOR A CONTAINER INCLUDING A MEDICINAL ACTIVE INGREDIENT - The invention relates to a connector for containers containing medicinal active ingredient, which connector makes it possible to transfer active ingredient from one container into another container. | 01-10-2013 |
20120313366 | CONNECTOR FOR CONTAINERS CONTAINING A MEDICINAL ACTIVE SUBSTANCE - The invention relates to a connector for containers ( | 12-13-2012 |
20120310177 | CONNECTOR SYSTEM FOR NUTRIENT CONTAINERS FOR ENTERAL NUTRITION - The present invention discloses an attachment ( | 12-06-2012 |
20120302962 | Tube for the enteral feeding of a patient - A tube unit for the enteral feeding of a patient, with a tube segment that extends along at least a segment of the axial direction (S) and a retention device on the distal end of the tube segment, which extends in at least one direction radially to axial direction (S) beyond the distal end of the tube segment in an extended position and which has a smaller diameter in an elongated position, in which the retention device is elongated along axial direction (S). The retention device moves from an extended position into the elongated position is supported by a control device. | 11-29-2012 |
20120273007 | Device for wetting a medical equipment component - The invention concerns a device ( | 11-01-2012 |
20120207636 | PUMP MODULE, PUMP BASE MODULE AND PUMP SYSTEM - The invention concerns a pump module, a pump base module and a pump system which comprises a pump module and a pump base module. | 08-16-2012 |
20120207635 | PUMP MODULE, PUMP MODULE AND PUMP SYSTEM - The invention concerns a wobble pump base module and a wobble pump system. The invention-based wobble pump base module ( | 08-16-2012 |
20120192976 | CONNECTION DEVICE FOR CONNECTING A FIRST RESERVOIR WITH A SECOND RESERVOIR - The invention concerns a connection device for connecting a first reservoir with a second reservoir, having
| 08-02-2012 |
20120163999 | PUMP MODULE, PUMP BASE MODULE AND PUMP SYSTEM - The invention-based pump module ( | 06-28-2012 |
20120111368 | PROTECTIVE CAP FOR A CONNECTOR - The invention relates to a protective cap for sealing a connector for a container containing medical substances, a connector system and a method for cleaning and/or disinfecting a surface of a recessed membrane of a connector. The protective cap ( | 05-10-2012 |
20120087991 | MUCOSITIS PREVENTION SUPPLEMENT AND TREATMENT - The present invention provides for a nutritional composition comprising from 0.25 g to 25 g of glutamine, in neutral or salt form or precursor or derivative thereof; and from 0.1 g to 10 g of a phytochemical or a mixture thereof, wherein the phytochemical is an antioxidant. The nutritional composition is particularly useful in the treatment and/or prevention of mucositis. | 04-12-2012 |
20120046619 | DRIP CHAMBER FOR AN INFUSION DEVICE AND INFUSION DEVICE HAVING A DRIP CHAMBER - The invention relates to a drip chamber for an infusion device and an infusion device having such a drip chamber, by means of which medical solutions can be fed to a patient, such as infusion solutions for chemotherapy. The drip chamber ( | 02-23-2012 |
20120035267 | PARACETAMOL FOR PARENTERAL ADMINSTRATION - The invention relates to an aqueous pharmaceutical composition, preferably an infusion solution, for parenteral administration which contains paracetamol and has an electrical conductivity of not more than 200 μS cm | 02-09-2012 |
20110257090 | SOLUTIONS FOR VOLUME THERAPY - The invention relates to artificial plasma-like solutions and methods for their use. The subject solutions find use in a variety of applications, particularly in those applications where at least a portion of a host's blood volume is replaced with a blood substitute. | 10-20-2011 |
20110245796 | CLOSURE CAP FOR RECEPTACLES FOR RECEIVING MEDICAL LIQUIDS AND RECEPTACLE FOR RECEIVING MEDICAL LIQUIDS - The invention relates to a closure cap ( | 10-06-2011 |
20110200555 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN - Conjugates of hydroxyalkyl starch and a protein are provided herein. The conjugates are formed by a convalent linkage between the hydroxyalkyl starch or a derivative of the hydroxyalkyl starch and the protein. Methods of producing the conjugates and the use of the conjugates also are provided herein. | 08-18-2011 |
20110198350 | DEVICE FOR OPENING A LINE - The present application relates to a device for opening a line, particularly the line of a blood tube or blood bag system, wherein the line has a sealing element that blocks the line passage, wherein the device comprises at least one opening unit ( | 08-18-2011 |
20110166532 | CONNECTOR HAVING A MEMBRANE, FOR CONNECTING A SYRINGE TO A CONTAINER OR TUBING - The invention relates to a device for connecting a syringe to a container or tubing, particularly for connecting a syringe to a container for receiving infusion-, transfusion-, or enteral nutrition solutions and particularly for connecting a syringe to tubing of a blood tube system of an extracorporeal blood treatment device or to tubing for a venous portal. The invention also relates to a container and tubing with such a device. The device according to the invention has a connecting part ( | 07-07-2011 |
20110137252 | DEVICE FOR PROVIDING A PERCUTANEOUS ENDOSCOPIC GASTROSTOMY - The device according to the invention for providing a percutaneous endoscopic gastrostomy (PEG) comprises a handle for handling the device. The wire that is to be inserted into the stomach of the patient is rolled on a wire spool that is mounted either in a rotatable manner on the handle part or on an attachment piece that can be attached to the handle. Aside from the puncturing cannula for puncturing the stomach, the device according to the invention comprises an insertion cannula for insertion the wire rolled on the wire spool into the stomach. The device according to the invention is characterized in that the puncturing cannula is designed as an outer cannula surrounding the insertion cannula, while the insertion cannula is designed as an inner cannula surrounded by the puncturing cannula, wherein the insertion cannula is guided into the puncturing cannula in a longitudinally displaceable manner. During the puncture of the stomach, the insertion cannula is recessed into the puncturing cannula. The design of the insertion cannula as an inner cannula and the puncturing cannula as an outer cannula provides the advantage that the puncture can be carried out only with the puncturing cannula. The design problem of an even transition between an insertion cannula as an outer cannula and a puncturing cannula as an inner cannula is solved by the device according to the invention. Moreover, puncturing and insertion cannulas made of steel can be produced with a comparable low technical effort and relatively low costs in great numbers without the need for both cannulas to be formed to each other for achieving a smooth transition. | 06-09-2011 |
20110054152 | Hydroxyalkyl Starch Derivatives - The present invention relates to a method of producing a hydroxyalkyl starch derivative comprising reacting hydroxyalkyl starch of formula (I) at its reducing end which is not oxidized prior to said reaction, with a compound of formula (II) R′NH—R″ (II) wherein R | 03-03-2011 |
20110022024 | CONNECTOR FOR PACKAGING CONTAINING MEDICAL FLUIDS AND PACKAGING FOR MEDICAL FLUIDS - The disclosure relates to a connector for packaging containing medical fluids, in particular infusion or transfusion bags, including a tubular connection part for receiving a spike for the withdrawal of fluid, and having a lower opening on the packaging side and an upper opening on the connection side. A self-sealing membrane, which is pierced by the spike, is located in the connection part. The membrane has an upper, annular section leading into a lower, plate-shaped section, said annular section of the membrane surrounding the spike in a sealing manner, when the latter pierces the plate-shaped section. The membrane acts as a guide for the spike and also reseals the connector, once the spike has been removed. | 01-27-2011 |
20100305033 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION - The invention relates to a method for the preparation of a hydroxyalkyl starch derivative which comprises reacting hydroxyalkyl starch (HAS) via the optionally oxidised reducing end of the HAS with the amino group M of a crosslinking compound which, apart from the amino group, comprises a specifically protected carbonyl group, namely an acetal group or a ketal group. | 12-02-2010 |
20100297078 | METHOD FOR PRODUCING A HYDROXYALKYL STARCH DERIVATIVE WITH TWO LINKERS - A method of producing a hydroxyalkyl starch (HAS) derivative, comprising a) reacting optionally oxidized hydroxyalkyl starch with a compound (D) comprising at least two functional groups —O—NH | 11-25-2010 |
20100262114 | PARISON AND METHOD FOR THE PRODUCTION OF A RECEPTACLE USED FOR HOLDING LIQUIDS FOR MEDICAL APPLICATIONS - The invention relates to a parison for producing a receptacle used for holding liquids for medical applications, especially for holding infusion solutions or enteral nutrient solutions. The invention further relates to a method for producing such receptacles as well as such a receptacle. The parison according to the invention comprises a neck part ( | 10-14-2010 |
20100189816 | Cachexia prevention supplement - The invention provides for a nutritional composition comprising from 0.1 to 10 g of eicosapentaenoic acid or a derivative thereof based on 100 kcal of the total composition; and from 0.1 to 10 g of a phytochemical or a mixture thereof based on 100 kcal of the total composition, for a use as a medicament for the treatment and/or prevention of cachexia and/or anorexia. The composition is particularly useful in the prevention of cachexia and is administered almost without any additional macronutrients in order to avoid a negative impact on the general diet of the patient. | 07-29-2010 |
20100062973 | Production of bioactive glycoproteins from inactive starting material - A method for preparing a conjugate comprising a glycoprotein and a polymer or a derivative of said polymer, wherein the polymer is a hydroxyalkylstarch (HAS), the method comprising the steps a) reacting said glycoprotein with a modified polyol carrying attached thereto, by a covalent linkage, a functional group Z, in the presence of a transferase capable of catalysing formation of a covalent linkage between the glycoprotein and said modified polyol, yielding a glycoprotein covalently linked to a polyol carrying attached thereto, by a covalent linkage, at least one functional group Z, and b) reacting at least one functional group A of the polymer or the derivative thereof with the at least one functional group Z of the glycoprotein added to said glycoprotein during step a), and thereby forming a covalent linkage. | 03-11-2010 |
20080274948 | Conjugates of Hydroxyalkyl Starch and G-Csf - The present invention relates to conjugates of hydroxyalkyl starch and a granulocyte colony stimulating factor protein (G-CSF) wherein these conjugates are formed by a covalent linkage between the hydroxyalkyl starch or a derivative of the hydroxyalkyl starch and the protein. The present invention also relates to the methods of producing these conjugates and the use of these conjugates. | 11-06-2008 |
20080230350 | Device for Delivering Packets Comprising a Pouring Spout - The invention relates to a device which is used to deliver packets ( | 09-25-2008 |
20080207562 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine - The present invention relates to a method for preparing conjugates of an active substance and hydroxyalkyl starch and to conjugates of an active substance and hydroxyalkyl starch, preferably hydroxyethyl starch, wherein the conjugates are prepared by covalently linking the hydroxyalkyl starch and the active substance by a chemical residue having a structure according to formula (I) | 08-28-2008 |
20080206182 | Conjugates of a Polymer and a Protein Linked by an Oxime Group - The present invention relates to polymers functionalized by an aminooxy group or a derivative thereof, conjugates, wherein the functionalized polymers are covalently coupled with a protein by an oxime linking group, a process for preparing the functionalized polymers, a process for preparing the conjugates, functionalize polymers as obtainable by the process of the present invention, conjugates as obtainable by the process of the present invention, and pharmaceutical compositions comprising at least one conjugate of the present invention and the use of said conjugates and compositions for the prophylaxis or therapy of the human or animal body. | 08-28-2008 |