Fenwal, Inc. Patent applications |
Patent application number | Title | Published |
20160103968 | Processing Blood Donation Data for Presentation on Operator Interface - A system and method processes blood donation data for presentation on an operator interface. A handheld computing device has a touch screen display and a processing circuit to provide an icon associated with an executable application on a first display screen, the icon configured to be positioned along with icons for other executable applications on the first display screen. The processing circuit is to retrieve an indication of a need for a particular blood component, wherein the particular blood component is selected from the group comprising whole blood, double red cells and plasma. The processing circuit is to provide the indication of the need for a particular blood component to the display. The processing circuit is to provide to the touch screen display a remaining time or a date the blood donor is next eligible to donate a blood component based on a donation eligibility guideline. | 04-14-2016 |
20160051744 | PARALLEL PROCESSING OF FLUID COMPONENTS - A kit for blood component processing comprising a fluid circuit into which blood is drawn, wherein the fluid circuit comprises a plurality of pathways; wherein the first pathway is configured to receive blood drawn from a blood source and leads to a separation device, wherein the separation device is configured to separate the blood into components; wherein the second pathway is configured to receive a first component from the separation device and transport at least a portion of the first component to a first processing device, wherein the first processing device may alter the first component to produce a first output; and wherein the third pathway is configured to receive a second component from the separation device and transport at least a portion of the second component to a second processing device, wherein the second processing device may alter the second component to produce a second output. | 02-25-2016 |
20150359959 | Method For Delivering Desired Light Dose To Cells In A Light Attentuating Medium - A method provided for determining a range for the amount of light-energy attenuating material that may be present in a suspension containing target cells (such as MNCs), light-energy attenuating matter (such as RBCs and plasma), and a light-energy activatable compound (such as psoralen) so that a desired therapeutic effect (such as the percentage of MNCs in which apoptosis occurs) is obtained when the suspension is subjected to a known amount of light energy. In a related aspect, a method is provided for preparing a suspension containing target cells, light-energy attenuating matter, and a light-energy activatable compound so that a desired therapeutic effect is obtained when the suspension is subjected to a known amount of light energy | 12-17-2015 |
20150320925 | Systems And Methods For Determining Replacement Fluid And Plasma Flow Rates For Red Blood Cell Exchange Procedures - Systems and methods for performing a red blood cell exchange procedure are disclosed. In one aspect, the flow rates of a replacement fluid (e.g., red blood cells from a healthy donor) and plasma being flowed to a blood source are calculated based on certain parameters of the procedure that are known, including the flow rate of blood being drawn from the source and the volume of replacement fluid to be used during the procedure. The replacement fluid flow rate and the plasma flow rate are calculated in a way that allows for simultaneous depletion of the supply of replacement fluid and achievement of another prescribed process parameter. The other prescribed process parameter depends on the nature of the procedure, namely whether the fluid volume and hematocrit of the source are to change by the end of the procedure or remain the same. | 11-12-2015 |
20150219558 | Interface Detector For Blood Processing System - Blood separation systems and methods are provided for controlling the interface between separated blood components. The system includes a centrifuge assembly having a light-transmissive portion, a light reflector, and a fluid processing region therebetween. An optical sensor system emits a scanning light beam along a path toward the light-transmissive portion, which transmits at least a portion of the scanning light beam to the fluid processing region and the light reflector. The light reflector reflects at least a portion of the scanning light beam toward the optical sensor system along a path substantially coaxial to the path of the scanning light beam from the optical sensor system toward the light-transmissive portion of the centrifuge assembly. The scanning light beam may be a white light beam or narrow spectrum beam. The reflected beam may be directed through the optical sensor system via optical fibers. | 08-06-2015 |
20150218517 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously-collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 08-06-2015 |
20150196706 | System and Method for Determining Irradiation Exposure Time with Irradiation Sensors During Extracorporeal Photopheresis - An irradiation device for photopheresis, comprising an exposure chamber configured to receive an illumination container holding a target cell suspension; an irradiation source configured to irradiate the illumination container and target cell suspension for a certain exposure time period; an irradiation sensor configured to detect the intensity of irradiation emitted by the irradiation source; and a processing circuit coupled to the irradiation sensor and configured to treat the target cell suspension with a predetermined treatment dosage of radiation, wherein the processing circuit adjusts the exposure time period based on the intensity of irradiation in order to achieve the predetermined treatment dosage. | 07-16-2015 |
20150186834 | SYSTEM AND METHOD FOR BLOOD COMPONENT SUPPLY CHAIN MANAGEMENT - Systems and methods for managing inventories of blood components are disclosed. Such systems and methods are configured to improve the predictability, efficiency, and/or automation of blood component supply chains. Tools are provided for tracking blood component inventories, forecasting blood component demand, and coordinating donations to meet current and anticipated demand. Some embodiments of the systems and methods identify when blood component units at a health care facility are beginning to run low or are approaching expiration, before the need for additional units becomes critical. Some embodiments of the systems and methods coordinate new donations and modify existing scheduled donations to meet real-time and forecasted demand for blood components. | 07-02-2015 |
20150182682 | METHOD FOR SIZED-BASED CELL SEPARATION USING SPINNING MEMBRANE FILTRATION - A method is provided for separating a suspension of cellular material comprising at least two differently-sized cell types using a spinning membrane separator. The method comprises selecting the cell type to be separated by passing through the membrane; determining a concentration of the selected cell type in the suspension; selecting an inlet flow rate for the suspension; selecting a rotational speed for the spinning membrane separator related to one or more of the concentration and relative size of the selected cell type in the suspension; rotating the spinning membrane separator at the selected rotational speed so that the selected cell type tends to migrate to regions of the shear field adjacent the porous membrane; and flowing the suspension through the spinning membrane separator. | 07-02-2015 |
20150135338 | DIGITAL CERTIFICATE WITH SOFTWARE ENABLING INDICATOR - A server computer has a network interface circuit and a processing circuit. The network interface circuit is configured to provide communications over a network. The processing circuit is configured to transmit over the network an electronic document comprising a digitally signed identity associated with the server computer. The electronic document further comprises a software enabling indicator, the software enabling indicator comprising data indicating whether a software feature of a system is to be enabled for use. | 05-14-2015 |
20150134359 | MEDICAL RECORD STORAGE WITH ELECTRONIC SIGNATURE - A server computer for storing an electronic medical record with an electronic signature in a database has a network interface circuit and a processing circuit. The network interface circuit is configured to provide communications over a network. The processing circuit is configured to receive an electronic medical record and store the electronic medical record in the database in compliance with at least one record storage criterion. After storing the electronic medical record in the database in compliance with the at least one record storage criterion, the processing circuit is configured to receive an electronic signature for the electronic medical record and store the electronic signature in association with the electronic medical record in the database. | 05-14-2015 |
20150115180 | METHOD AND APPARATUS TO VERIFY CORRECT REPLACEMENT FLUID IN A THERAPEUTIC EXCHANGE PROCEDURE - A method and apparatus are provided for automatically detecting the type of replacement fluid loaded by the operator during a therapeutic exchange procedure and to provide a warning alarm if an incorrect fluid is used. After the operator connects the container of replacement fluid to the replacement fluid line of a single-use kit and enters into the controller an identification of the exchange procedure to be performed, the replacement fluid is flowed through a segment of the kit in proximity to a sensor associated with the hardware component that detects the type of fluid flowing through the segment. The controller verifies whether the replacement fluid detected in the segment corresponds to that appropriate for the selected exchange procedure, and notifies the operator in the event that an incorrect replacement fluid has been loaded. | 04-30-2015 |
20150101994 | SYSTEMS AND METHODS FOR MINIMIZING LOSS OF CELLULAR COMPONENTS DURING APHERESIS - Systems and methods for processing a fluid including a suspension of biological cellular components are disclosed including a single-use kit comprising a container for the fluid; a separation device for retaining selected biological cellular components and allowing other biological cellular components of said fluid to pass therethrough; a flow path connecting the container to the separation device, the container being configured, when in use, to be positioned so that gravity tends to flow fluid through the flow path. The flow path has a segment in close proximity to the container with a configuration including a positive slope, so that biological cellular components moving through the segment are subjected to a gravitational force tending to impede movement through the flow path segment. The flow path segment preferably has a generally circular configuration, and a diameter of approximately 1.5 inches. Alternatively, the flow path segment may have a generally S-shaped configuration. | 04-16-2015 |
20150060363 | DEVICE AND METHOD FOR PROCESSING AND PRODUCING AUTOLOGOUS PLATELET-RICH PLASMA - A system and method are provided, including an integrated single-use kit, for processing whole blood to produce platelet rich plasma. A two stage spinning membrane separator, has a first stage for receiving whole blood and separating substantially all red blood cells from plasma and platelets, and a second stage for further separating platelet rich plasma from plasma. A first waste container is in fluid communication with the first stage of the separator for receiving separated red blood cells, while a second waste container is in fluid communication with the second stage of the separator for receiving separated plasma. An outlet line is in fluid communication with the second stage of the separator for receiving platelet rich plasma, and a reinfusion container is removably connected to the outlet line for receiving platelet rich plasma from the second stage of the separator. | 03-05-2015 |
20150056602 | APHERESIS PLATELETS WITH FIXED RESIDUAL PLASMA VOLUME - Methods and systems for obtaining platelets are disclosed. Platelets are collected in a pre-determined volume of plasma and a determined amount of a combined storage medium including the pre-determined amount of plasma and a volume of a synthetic additive solution. | 02-26-2015 |
20140350450 | PERFORMING AN APHERESIS PROCEDURE ON A HUMAN SUBJECT WITH IDENTITY INPUT DATA - Systems and methods are provided for performing a medical procedure with respect to a subject. A data storage location of the system is pre-programmed with a plurality of subject data entries, each having subject-specific information associated with it. A user interface receives an identity input from a subject, which corresponds to the identity of the subject. A controller is associated with the database and the user interface, and is programmed to compare the identity input to the subject data entries. If the identity input corresponds to the subject-specific information of a subject data entry, the controller commands a treatment device to perform a medical procedure with respect to the subject. Otherwise, if the identity input does not correspond to the subject-specific information of any of the subject data entries, the controller generates an error signal which prevents the performance of the medical procedure with respect to the subject. | 11-27-2014 |
20140291248 | SYSTEMS AND METHODS FOR USE AND CONTROL OF AN AUTOMATED SEPARATOR WITH ADSORPTION COLUMNS - Blood treatment systems and methods are provided for combining a blood separation system and an adsorption device. The blood separation system is configured to separate a blood component from blood, while the adsorption device is configured to receive at least a portion of the separated blood component and process it. The blood separation system includes a fluid flow element and a controller. The fluid flow element is configured for flowing the separated blood component into the adsorption device. The controller controls the fluid flow element based at least in part on one or more processing parameters. The processing parameters include a maximum flow rate of the separated blood component flowed into the adsorption device, a maximum pressure of the separated blood component flowed into the adsorption device, and/or the volume of fluid in a location of the system. | 10-02-2014 |
20140276527 | MEDICAL CONTAINERS WITH TEREPHTHALATE PLASTICIZER FOR STORING RED BLOOD CELL PRODUCTS - Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells. | 09-18-2014 |
20140274648 | MULTILUMEN CONNECTOR TO MULTIPLE INDIVIDUAL TUBING - An umbilicus for use in an umbilicus-drive fluid processing centrifuge system is disclosed, together with a method of making it and a fluid flow circuit including such umbilicus. The umbilicus includes an elongated umbilicus body, a first end fitting defining an interior cavity, an adapter received within the interior cavity and having at least one port extension extending into a fluid transmitting lumen of the umbilicus body, the adapter and end fitting including interfering surfaces to enhance torque resistance therebetween. | 09-18-2014 |
20140263529 | AUTOMATED FRANGIBLE CANNULA BREAKER - Apparatus and method are disclosed for opening a frangible internal cannula located in flexible fluid flow path. The frangible cannula has first and second portions joined by a frangible junction and the apparatus and method cause bending of one portion of the cannula relative to the other portion that results in breaking of the frangible junction and opening of the flow path to fluid flow therethrough. | 09-18-2014 |
20140252078 | COUNTERFEIT PROTECTION AND VERIFICATION SYSTEM AND METHOD - A system is provided comprising first and second parts that are brought together for each occasion the system is used. The first part comprises a label having a plurality of discrete magnetic portions arranged in a predetermined pattern unique to the first part, and the second part comprises a magnetic reader for identifying the magnetic pattern on the first part and generating a signal indicative of the pattern. The second part also includes a programmable controller configured to receive signals from the reader to confirm the identity of the first part and permit further operation of the system upon a positive identification of the first part. | 09-11-2014 |
20140231365 | Optical Detection Of Lipids - Blood separation systems and methods are provided for detecting lipids in plasma that has been separated from a plasma-containing fluid, such as blood. The system includes a fluid processing region in which a plasma-containing fluid is separated into plasma and other fluid components. A plasma flow path is associated with the fluid processing region for the flow of at least a portion of the separated plasma into or out of the region. A lipid detector shines blue and/or ultraviolet light through the separated plasma in the plasma line to optically detect the presence of lipids therein. The lipid detector may be used alone or in combination with a hemoglobin detector to reduce the number of false hemoglobin alarms or an interface detector for improved detection and correction of the location of an interface between separated fluid components in the fluid processing region. | 08-21-2014 |
20140230944 | Low Cost Umbilicus Without Overmolding - An umbilicus is provided for use in an umbilicus-driven fluid processing system. The umbilicus includes an umbilicus body having enlarged first and second ends, with an intermediate section located therebetween. At least one fluid-transmitting lumen extends between the first and second ends. The umbilicus further includes first and second end fittings, each associated with one of the ends of the umbilicus body. Each end fitting defines an interior cavity having a flared portion, with at least a portion of one of the enlarged ends of the umbilicus body being seated within the flared portion. The enlarged ends of the umbilicus body may be formed using a heated die at least partially inserted into the fluid-transmitting lumen. | 08-21-2014 |
20140199680 | DISPOSABLE FLUID CIRCUITS AND METHODS FOR CELL WASHING - Systems and methods for the washing and processing of biological fluid/biological cells are disclosed. The systems and methods utilize a disposable fluid circuit including a spinning membrane separation device to wash the biological cells. | 07-17-2014 |
20140132945 | CITRATE DETECTOR FOR BLOOD PROCESSING SYSTEM - A citrate detector is provided for use in combination with a blood processing system and replacement fluid tubing or conduit of a disposable set. The citrate detector comprises a light source and a light detector. The light source is configured to emit a light having a wavelength absorbed by citrate, but at least partially transmitted by the replacement fluid conduit of the disposable set. The light detector is configured to receive at least a portion of the light from the light source and generate a signal indicative of the presence or absence of citrate in the replacement fluid conduit based, at least in part, on the amount of light received from the light source. A blood processing system incorporating such a citrate detector may include a flow detector for determining whether fluid is present in the conduit prior to checking for the presence of citrate. | 05-15-2014 |
20140128832 | RFID TAG AND BLOOD CONTAINER/SYSTEM WITH INTEGRATED RFID TAG - The present disclosure relates to arrangements for attaching an RFID tag to a liquid container, and particularly to a blood components container. The RFID tag may be inserted in an enclosure, such as peel tab, or in a sealed cup attached to a container port. The tag could alternately be embedded in a molded plug or component attached to a port. The RFID antenna could be painted or stamped on the surface of the container. Or the tag could be inserted into the container to float freely in the liquid components. The RFID source may be secured around the neck of a rigid or semi-rigid container, attached with a tether or attached to a connector assembled in association with a blood component or other fluid flow path. | 05-08-2014 |
20140093189 | CONTAINERS AND COMPONENTS THEREOF FOR USE IN THE MEDICAL INDUSTRY AND METHODS TO MANUFACTURE SAME - Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals. | 04-03-2014 |
20140080113 | BLOOD COMPONENT SAMPLING SYSTEM AND BLOOD PROCESSING SYSTEMS AND METHODS EMPLOYING SAME - A blood component sampling system and method are disclosed. The system is pre-connected and includes a collected blood component container and a reservoir having substantially fixed volume and at least one volumetric indicator indicating a selected volume and a sample container docking station configured to cooperate with a sample collection container. The system and method provide ease of sampling with reduced risk of contamination. | 03-20-2014 |
20140077488 | FLUID FLOW CONDUITS AND APPARATUS AND METHODS FOR MAKING AND JOINING FLUID CONDUITS - Fluid flow conduits and apparatus and methods for joining the conduits, preferably in a sterile manner, are disclosed. Each conduit has a polymeric open end that is sealed by a sealing member that may include a heating element. The polymeric end material is melted, the sealing members are moved to expose the melted open ends of the conduits and the ends are brought together to form a fused or welded connection between the conduits. | 03-20-2014 |
20140074047 | NON-REOPENABLE FLOW CONTROL CLAMP - The present disclosure relates to clamps for controlling the flow of liquid through a fluid circuit. More particularly, the present disclosure relates to flow control clamps that can be substantially irreversibly secured in a closed position, thereby preventing reopening of the flow path of the tube and providing a sterile closure. | 03-13-2014 |
20140069868 | Methods for Automated Blood Prime - A method is disclosed for priming a kit for use in a therapeutic apheresis procedure with previously-collected blood prior to flowing the patient's whole blood into the inlet line of the kit, as part of a procedure in which a selected blood component is separated from a patient's whole blood, and replaced with a previously-collected blood component. The operator enters into the controller of the separation device the hematocrit value of the previously-collected blood. Then, in response to prompts by the controller, the operator enters a target hematocrit value for the previously-collected blood and an identification of the portion of the kit to be primed. The identified portion of the kit is automatically primed with the previously-collected blood. The patient is then connected to the inlet line of the kit in response to a prompt from the controller and the therapeutic procedure is commenced. | 03-13-2014 |
20140057771 | OPTICAL MONITORING SYSTEM FOR BLOOD PROCESSING SYSTEM - An optical monitoring system is provided for use with a blood processing system. The system includes a light source configured to illuminate a disposable flow circuit received in a centrifuge and a light detector configured to receive an image of the disposable flow circuit. A controller combines two or more of the images received by the light detector to generate a two-dimensional output. The output is used to control the separation of blood within the disposable flow circuit. The monitoring system may also be used to verify that the disposable flow circuit is suitable for use with the centrifuge or that the disposable flow circuit is properly aligned within the centrifuge. The monitoring system may be positioned outside of the centrifuge bucket which receives the centrifuge. | 02-27-2014 |
20140045671 | CENTRIFUGATION SYSTEM WITH RED BLOOD CELL BARRIER - Centrifugation systems and methods are provided for separating blood into its constituent parts. Inner and outer walls of a centrifuge each include a projection which extends toward the other wall. A separation chamber is received in the centrifuge between the walls, with the chamber including an inlet port for flowing blood into the chamber, a plasma outlet port for flowing plasma out of the chamber, and a red cell outlet port for flowing red blood cells out of the chamber. With the chamber received in the centrifuge between the walls, the first projection extends into the path of separated blood components flowing toward the plasma outlet port and prevents cellular blood components from flowing into the plasma outlet port. The second projection extends into the path of separated blood components flowing toward the red cell outlet port and prevents plasma from flowing into the red cell outlet port. | 02-13-2014 |
20140045668 | OPTICAL MONITORING SYSTEM FOR BLOOD PROCESSING SYSTEM - An optical monitoring system is provided for use with a blood processing system. The system includes a light source configured to illuminate a disposable flow circuit received in a centrifuge and a light detector configured to receive an image of the disposable flow circuit. A controller combines two or more of the images received by the light detector to generate a two-dimensional output. The output is used to control the separation of blood within the disposable flow circuit. The monitoring system may also be used to verify that the disposable flow circuit is suitable for use with the centrifuge or that the disposable flow circuit is properly aligned within the centrifuge. The monitoring system may be positioned outside of the centrifuge bucket which receives the centrifuge. | 02-13-2014 |
20140043930 | PLATELET RESUSPENSION METHOD AND APPARATUS - A method is disclosed for resuspending a concentrated blood component collected in a single-use processing chamber that is mounted to a rotatable support of a centrifugal collection system. A resuspension solution is introduced to the single-use processing chamber constraining the concentrated blood component. The rotatable support with the single-use processing chamber mounted thereto is removed from the centrifugal collection system and mounted to a resuspension device. The device is then activated for a period of time sufficient to resuspend the concentrated blood component in the resuspension solution. In another aspect, the resuspension device is configured to impart a reciprocating arcuate motion to the support and its associated single-use processing chamber. A frequency of approximately 300 to 325 rpm over a period of time of approximately 1.5 to 2.5 minutes has been found effective for resuspending platelets. Reciprocation through an arc of less than 200° is provided. | 02-13-2014 |
20140042049 | CONTAINERS AND COMPONENTS THEREOF FOR USE IN THE MEDICAL INDUSTRY AND METHODS TO MANUFACTURE THE SAME - Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals. | 02-13-2014 |
20140038760 | DRIVE SYSTEM FOR CENTRIFUGE - A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular ve | 02-06-2014 |
20140037750 | AUTOMATED METHODS AND SYSTEMS FOR PROVIDING PLATELET CONCENTRATES WITH REDUCED RESIDUAL PLASMA VOLUMES AND STORAGE MEDIA FOR SUCH PLATELET CONCENTRATES - Automated systems and methods for providing platelet concentrates and synthetic storage media with reduced residual plasma volumes are disclosed. The disclosed systems and methods reduce the residual volume of plasma in platelet concentrate to obtain a platelet product having a volume of plasma that is approximately 5% or less of the total platelet product volume. The disclosed systems and methods also reduce the residual volume of plasma in platelet concentrate to obtain a washed platelet product, wherein the volume of plasma in the washed platelet product is approximately 1% or less of the total washed platelet product volume. Storage media for platelets including less than approximately 10% plasma are also disclosed. | 02-06-2014 |
20140034230 | FLUID FLOW CONDUITS AND APPARATUS AND METHODS FOR MAKING AND JOINING FLUID CONDUITS - Fluid flow conduits ( | 02-06-2014 |
20140033864 | DRIVE SYSTEM FOR CENTRIFUGE - A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly ( | 02-06-2014 |
20140010738 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device for use in blood processing procedures is disclosed. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 01-09-2014 |
20140008277 | Control Of Interface Between Separated Blood Components Under Lipemic And Hemolytic Conditions - Blood separation systems and methods are provided for controlling the interface between separated blood components. The system includes a blood separation chamber configured to separate blood into first and second blood components and an outlet line for removing at least a portion of the first blood component from the blood separation chamber. A primary optical sensor assembly is associated with the blood separation chamber to directly monitor the interior of the blood separation chamber. A secondary optical sensor assembly is associated with the outlet line to monitor the first blood component in the outlet line. The system also includes a controller programmed to select between the primary optical sensor assembly and the secondary optical sensor assembly for monitoring contamination of the first blood component. The system is particularly advantageous for preventing contamination of separated plasma which is lipemic or hemolytic. | 01-09-2014 |
20130345674 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 12-26-2013 |
20130341291 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 12-26-2013 |
20130341275 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 12-26-2013 |
20130341274 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 12-26-2013 |
20130340884 | MEDICAL CONTAINERS FOR USE IN BLOOD COLLECTION AND PROCESSING AND MEDICAL SYSTEMS, METHODS AND APPARATUS FOR USE IN BLOOD COLLECTION AND PROCESSING - Medical containers for use in blood collection and processing and medical systems, methods and apparatus for use in blood collection and processing are described. An example medical container to be used during blood collection and processing, the medical container includes an elongated body defining a compartment and a base coupled at a first end of the elongated body. Additionally, the medical container includes a divider extending through the compartment to separate the compartment into a first subcompartment and a second subcompartment, the divider comprising a first material and the elongated body comprising a second material, the first material being relatively more rigid than the second material, the first subcompartment and the subsecond compartment each to accommodate blood pack components. | 12-26-2013 |
20130334420 | Process for Predicting Hematocrit of Whole Blood Using IR Light - A separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided. Automated systems and methods are disclosed for separating a unit of previously-collected whole blood into selected blood components, such as concentrated red cells and plasma, including prediction of the hematocrit of the whole blood using a light source and an optical sensor. | 12-19-2013 |
20130334139 | MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS - A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed. | 12-19-2013 |
20130324974 | ENSURED COMPONENT BONDING - A tube connector includes a flexible member that engages an inserted length of tubing. The flexible member is configured to adhere to the tubing in the presence of an applied solvent, thereby forming a hermetic seal. | 12-05-2013 |
20130320249 | DONOR TUBE SEALING HEAD WITH NON-TENSION TUBE SUPPORTS - A blood donor tube sealing apparatus includes a housing configured to house an electronic circuit configured to provide a radio frequency signal. The sealing apparatus further includes a sealing device coupled to the housing. The sealing device includes a movable sealing head and at least one movable tube support. The movable sealing head and movable tube support are configured to be moved into contact with a blood donor tube. The movable sealing head is powered by the radio frequency signal to seal the blood donor tube. | 12-05-2013 |
20130304039 | MULTI-LUMEN TUBING TO SINGLE LUMEN TUBING CONNECTOR - A connector for a fluid handling system includes a body defining a plurality of internal passages that connect single-lumen tubes to lumens of a multi-lumen tube. Openings located along an internal edge of connector provide fluid communication between the internal passages and openings located along a curved outer surface of the multi-lumen tube. | 11-14-2013 |
20130267884 | Systems and Methods for Achieving Target Post-Procedure Fraction of Cells Remaining, Hematocrit, and Blood Volume During a Therapeutic Red Blood Cell Exchange Procedure With Optional Isovolemic Hemodilution - Systems and methods for performing a therapeutic red blood cell exchange procedure are disclosed. In one aspect, a system includes a first flow path for flowing whole blood from a patient. A separator communicates with the first flow path for separating at least red blood cells from plasma. Second and third flow paths communicate with the separator for respectively flowing the separated plasma and red blood cells from the separator. A flow controller is associated with the flow paths to control fluid communication between the flow paths. The controller is configured to perform the procedure to achieve a target fraction of patient cells remaining, target hematocrit, and a target patient fluid volume change at the completion of the procedure based on data input by the operator. | 10-10-2013 |
20130252227 | Apparatus and Method for Providing Cryopreserved ECP-Treated Mononuclear Cells - An apparatus and method for providing cryopreserved mononuclear cells that have been treated by extracorporeal photopheresis (“ECP”) is disclosed. More specifically, the present disclosure relates to providing ECP treated mononuclear cells that retain their apoptotic properties after cryopreservation and subsequent thawing. | 09-26-2013 |
20130248040 | UMBILICUS FOR USE IN AN UMBILICUS-DRIVEN FLUID PROCESSING SYSTEM - An umbilicus is provided for use in an umbilicus-driven fluid processing system. The umbilicus has a pair of anchor portions, at least one fluid-transmitting lumen, and a drive shaft. The fluid-transmitting lumen and drive shaft extend between the anchor portions. The lumen and drive shaft may be comprised of different materials. If multiple lumen are provided, they may either be separate from each other and the drive shaft or defined in a single umbilicus body which also provides a lumen for receiving at least a portion of the drive shaft. | 09-26-2013 |
20130237946 | Sterile Openable Access Port and Containers Including the Same - A connector for providing sterile access to a flexible container is provided that comprises a tubular member having a first portion and a second portion, each of the first portion and the second portion having an open end. The first portion and second portion are joined to each other by a frangible segment, with each of the first portion and the second portion having a gripable surface associated therewith that is configured to facilitate the application of torsional force to the tubular member at the frangible segment. Upon the application of a sufficient amount of torsional force, the frangible segment will break, permitting the first and second portions to be separated from each other. | 09-12-2013 |
20130233394 | Automatic Fluid Container Switching In A Blood Processing System - Systems and methods for determining when a fluid supply container of a blood processing apparatus becomes empty. The system uses a scale to monitor and detect when a fluid supply container is empty based on the rate of change of the container weight and whether the container weight is below a pre-established threshold, and a controller receives a signal from the scale and controls the operation of a pump to stop pumping when the fluid supply container is empty. | 09-12-2013 |
20130222108 | AUTHORIZATION SCHEME TO MINIMIZE THE USE OF UNAUTHORIZED MEDICAL DEVICE DISPOSABLES ON A MEDICAL DEVICE INSTRUMENT - Systems, methods, apparatus, and computer readable media are provided for disposable component authentication with respect to a biological fluid processing device instrument. An example instrument authentication system includes a computer facilitating configuration and operation of the biological fluid processing instrument using a disposable component. A first interface is provided by the computer and is used by a service technician to configure the biological fluid processing instrument for a number of disposable components and to provide a service technician with a validation code. A key generator is to accept the validation code from the service technician and generate an authentication key in response to the entered validation code. A second interface is provided by the computer, the second interface prompting the service technician to enter an authentication key, wherein the authentication key authorizes use of a certain number of disposable components for the biological fluid processing instrument. | 08-29-2013 |
20130220925 | METHODS AND SYSTEMS FOR PROVIDING RED BLOOD CELL PRODUCTS WITH REDUCED PLASMA - Methods and systems for processing and conditioning red blood cells are disclosed. The methods and systems may be used to make a readily transfusible red blood cell product with reduced plasma. In general, the plasma content of the supernatant of the red blood cell product is no greater than about 15%. The red blood cell products are prepared using the disclosed methods and systems remain transfusible for up to 42 days. | 08-29-2013 |
20130203582 | Method and Apparatus for Concentrating Platelets From Platelet-Rich Plasma - An apparatus for use with a centrifugal cellular separation device that comprises a rotor rotatable about an axis of rotation is provided that comprises a fluid separation chamber having a first port, a second port spaced apart from the first port, and a third port located intermediate the first port and the second port. The fluid separation chamber has a cross sectional area generally transverse to a radius extending from the axis of rotation that varies between the first port and the second port. The fluid separation chamber is adapted to be mounted to the rotor so as to be rotatable therewith, with the first port located at a greater radial distance from the axis than the second port, and the third port located radially intermediate the first port and the second port. | 08-08-2013 |
20130203042 | METHODS AND SYSTEMS FOR PROCESSING BIOLOGICAL FLUIDS - Methods and container systems for processing biological fluids are disclosed. The container systems include an inner container within an outer container. The inner container wall is made of a porous material of a selected porosity that allows certain components to pass through said porous wall but retains other components. A treating solution is introduced into the chamber of the outer container. | 08-08-2013 |
20130197419 | SYSTEMS AND METHODS FOR PERFORMING ONLINE EXTRACORPOREAL PHOTOPHERESIS - Systems and methods for performing online extracorporeal photopheresis of mononuclear cells are disclosed. Whole blood is removed from a patient and introduced through a processing set into a separation chamber to separate the desired cell population from the blood. The separated cell population is processed through the set which is associated with a treatment chamber where the cells are treated. Once treated, the cells are returned to the patient. The processing set remains connected to the patient during the entire ECP treatment procedure and provides an online, sterile closed pathway between the separation chamber and the treatment chamber. | 08-01-2013 |
20130190674 | USING PHYSIOLOGICAL DATA IN A MEDICAL DEVICE - Systems and methods for using physiological data in a medical device are disclosed. The physiological data may be measured by a vital sign reader and received by a processing circuit associated with the medical device. The processing circuit may automatically adjust the operation of the medical device during a medical procedure based on the physiological data. In some implementations, the processing circuit may mirror a memory partition to a redundant storage device, allowing for uninterrupted execution of the medical procedure in the event of a memory failure condition. | 07-25-2013 |
20130184686 | Flexible Medical Tubing Having Kink Resistant Properties And Methods And Apparatus To Produce The Same - A flexible, kink-resistant medical tube and a method and apparatus for making the same are provided. The tube includes a body having a first end, a second end, an outer surface and an inner surface. The tube includes a lumen defined by the inner surface of the body and extending between the first end and the second end. The tube also includes a helical structure within in the body. | 07-18-2013 |
20130168279 | CONTAINER WITH pH INDICATOR - Containers with pH indicators are disclosed. The pH indicator is in contact with the contents of a container and detects changes in the pH of the contents. | 07-04-2013 |
20130153484 | FLUID SEPARATORS EMPLOYING A FLUIDIC BEARING - A fluid separation device is provided with an outer housing and a rotor rotatably received within the outer housing. The rotor housing has a first end and a second end. The outer surface of the rotor and/or the inner surface of the outer housing is adapted to allow passage of a fluid component through the surface. The device further includes a flexible seal associated with one of the ends of the rotor and adapted to allow for rotational, non-axial, and axial movement of the rotor with respect to the outer housing. | 06-20-2013 |
20130150225 | PRESSURE SENSOR - One embodiment relates to a pressure sensor apparatus, including a housing with a flexible member and an aperture configured to receive a fluid. The pressure sensor apparatus further includes a first member disposed on the flexible member, a second member removeably coupled to the first member configured to move in response to a pressure of the fluid and a sensor configured to detect the movement of the second member. The pressure sensor apparatus generates a pressure signal for the fluid based on the displacement of the second member | 06-13-2013 |
20130138452 | MOBILE APPLICATIONS FOR MEDICAL DEVICES - Certain examples provide systems, methods, and apparatus to provide information regarding medical devices via a mobile device. An example method for mobile medical device management includes providing a representation of one or more medical devices with a visual indication of a status for each device. The representation is to visually convey information regarding each of the one or more medical devices and is selectable by a user to provide additional information regarding each of the one or more medical devices. The method includes facilitating interaction with the one or more medical devices via the mobile device. The method includes dynamically updating the status for each medical device via communication between the mobile device and one or more facilities at which the one or more medical devices are located. | 05-30-2013 |
20130096462 | Phlebotomy Needle Assembly And Frangible Cover - Medical needle assemblies incorporating a needle cover are provided. According to one aspect, the needle cover is integrally formed from a material that: (1) is sufficiently rigid to prevent bending of an underlying cannula, (2) is suitable for allowing a frangible portion thereof to be broken under pre-selected conditions, and/or (3) has a moisture vapor transmission rate sufficient for steam sterilization of a needle tip enclosed by the needle cover. According to another aspect, at least part of a cap portion and a hub portion of the needle cover are translucent. According to yet another aspect, the needle cover is provided with a wing having an enlarged rib suitable for gripping during separation of a cap portion from the remainder of the needle cover. | 04-18-2013 |
20130092319 | Flexible Housing Filter And Methods For Making Such Filter - A method for manufacturing a blood filter assembly is provided that includes the steps of providing a first housing sheet and a second housing sheet. The method includes locating and sealing at least one port onto each of the first and second housing sheets. The method includes locating the filtration medium between the first housing sheet and the second housing sheet. The method includes applying heat and pressure to form at least one seal that commingles the first and second housing sheets along with the filtration medium, wherein the periphery of the seal commingles only the first and second housing sheets. | 04-18-2013 |
20130079753 | Flexible Medical Tubing Having Kink Resistant Properties And Methods And Apparatus To Produce The Same - A flexible, kink-resistant medical tube and a method and apparatus for making the same are provided. The tube includes a body having a first end, a second end, an outer surface and an inner surface. The tube includes a lumen defined by the inner surface of the body and extending between the first end and the second end. The tube also includes a helical structure within the body. The helical structure may be formed either during or after an extrusion process or by steps taken both during and after the extrusion process. | 03-28-2013 |
20130036824 | PRESSURE SENSOR - A pressure sensor has a housing, a movable member and a vision sensor. The housing has an aperture configured to receive a fluid. The movable member is disposed in the housing and configured to move in response to a pressure of the fluid. The vision sensor is configured to detect the movement of the movable member. | 02-14-2013 |
20130018353 | MULTI-CHAMBER CONTAINER WITH SEAL BREACH DETECTION - A container having multiple compartments formed by frangible seals in the interior chamber of the container is disclosed. The container comprises an indicator adapted to provide an indication that a seal breach between the chambers has occurred. Methods of forming a container having a seal breach detection indicator are also disclosed. | 01-17-2013 |
20120282234 | Medium, Solutions And Methods For The Washing, Culturing And Storage Of White Blood Cells - White blood cell products and storage media for white blood cells are disclosed. The storage medium includes sodium chloride, sodium acetate, sodium citrate, sodium phosphate, magnesium chloride, potassium chloride, sodium bicarbonate, and glucose. White blood cells stored in such medium remain viable for at least up to 72 hours. | 11-08-2012 |
20120269679 | SINGLE COLLECTION BAG BLOOD COLLECTION SYSTEM, METHOD AND APPARATUS - A blood or blood component collection and processing system, apparatus and method are disclosed. One embodiment includes a vascular access device and a blood collection container having a blood inlet and first and second blood component outlets. The outlets are located at opposite ends of the container, and a blood flow conduit extends between the vascular access device and collection container. The collection container is free of attachment to other blood collection containers when in an initial collection configuration at the time of collection. | 10-25-2012 |
20120225419 | METHODS AND SYSTEMS FOR PROVIDING RED BLOOD CELL PRODUCTS WITH REDUCED PLASMA - Methods and systems for processing and conditioning red blood cells are disclosed. The methods and systems may be used to make a readily transfusible red blood cell product with reduced plasma. In general, the plasma content of the supernatant of the red blood cell product is no greater than about 15%. The red blood cell products are prepared using the disclosed methods and systems remain transfusible for up to 42 days. | 09-06-2012 |
20120204990 | Sterile Docking Device, Medical Fluid Flow System With Sterile Docking Device and Method Of Using Same - Method and apparatus are disclosed for forming a sealed communication between conduits or conduit subassemblies, each of which has a wall with an exterior surface, and at least one of the walls includes an electrically conductive portion. The exterior surfaces may be brought into a facing relationship, and each conductive portion is heated sufficiently to sterilize the exterior surfaces of the walls by generating electrical current in the conductive portion, such as by application of a voltage or by induction. An aperture is then provided, as by an aperture-forming member, through the facing walls to provide communication between the conduits or conduit subassemblies. | 08-16-2012 |
20120172755 | Irreversibly Closable Flow Control Clamp - A flow control clamp having a first member and a second member movable from a first open position to a second irreversibly closed position wherein flow through a tube associated with the clamp is irreversibly prevented and cannot be restored. Systems and methods using such clamps are also disclosed. | 07-05-2012 |
20110117647 | Red Blood Cell Storage Medium For Extended Storage - Synthetic aqueous storage solutions are disclosed for use in the processing and the storing of red blood cells prepared from whole blood including cells derived from whole blood held for an extended period at room temperature. | 05-19-2011 |
20100294693 | CONTAINERS AND COMPONENTS THEREOF FOR USE IN THE MEDICAL INDUSTRY AND METHODS TO MANUFACTURE THE SAME - Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals. | 11-25-2010 |
20100168639 | System and Method For Controlling Patient Fluid Balance And/Or Flow Rate For A Therapeutic Plasma Exchange Procedure - Systems and methods for controlling fluid flow during a fluid exchange procedure. In one aspect, a system is provided for controlling a net fluid volume difference of a patient during and/or after a fluid exchange procedure. The system comprises a first flow path for flowing at least a first fluid from the patient and a second flow path for flowing at least a second fluid to the patient. First and second reservoirs are respectively associated with the first and second flow paths. A controller is associated with the first and second flow paths for controlling first and second flow rates and operable to determine an actual flow rate for each first and second fluid and to change a first or second flow rate in response to a difference between at least one of such flow rates and its respective actual flow rate. | 07-01-2010 |
20100084332 | FLEXIBLE HOUSING FILTER AND METHODS FOR MAKING SUCH FILTER - A method for manufacturing a blood filter assembly is provided that includes the steps of providing a first housing sheet and a second housing sheet. The method includes locating and sealing at least one port onto each of the first and second housing sheets. The method includes locating the filtration medium between the first housing sheet and the second housing sheet. The method includes applying heat and pressure to form at least one seal that commingles the first and second housing sheets along with the filtration medium, wherein the periphery of the seal commingles only the first and second housing sheets. | 04-08-2010 |
20100049542 | SYSTEMS, ARTICLES OF MANUFACTURE, AND METHODS FOR MANAGING BLOOD PROCESSING PROCEDURES - Systems, articles of manufacture, and methods for managing blood processing operations and data for one or more blood component collection facilities are provided. An example system for networking the blood component collection facility includes a system computer including a memory and a communication interface. The system computer is linked to a plurality of input devices for tracking donors, operators, soft goods, and blood component collection instruments with respect to one or more blood product collection procedures. The system computer is also linked to at least one administrative level computing device to monitor blood component collection activities throughout the blood component collection facility and to facilitate decision making with respect to allocation of at least one of donors, operators, soft goods, and blood component collection instruments based on information regarding at least one of donors, operators, soft goods, and blood component collection instruments. | 02-25-2010 |
20090291819 | BLOOD SEPARATION CHAMBER - A method for centrifugally separating whole blood into red blood cells and a plasma constituent rotates about a rotational axis a separation zone having radially spaced apart walls with a high-G side and a low-G side located closer to the rotational axis than the high-G side. Whole blood enters the rotating separation zone in an entry region to begin separation. Separation is halted by a terminal wall that is circumferentially spaced from the entry region. The whole blood separates into red blood cells toward the high-G side and plasma constituent toward the low-G side. The method directs red blood cells separated in the separation zone in a circumferential flow direction toward the terminal wall. The method directs separated red blood cells from the rotating separation zone through a second path that extends, at least in part, radially beyond the high-G wall. | 11-26-2009 |