CAMBRIDGE BIOSTABILITY LIMITED Patent applications |
Patent application number | Title | Published |
20100114014 | PHARMACEUTICAL COMPOSITIONS STABILISED IN GLASSY PARTICLES - Present proposals for liquid-medium carriers for glass particles comprising pharmaceutical compositions have had problems associated with aggregation of the glass particles. This has been previously solved by matching the density of the particles and a liquid in which they are suspended. However, though this greatly constrains the choice of liquid carrier that can be used. An alternative solution to this problem has been found. By adding just a small amount of liquid ( | 05-06-2010 |
20090208585 | STABILISATION OF BIOLOGICAL MATERIALS - Biological materials such as vaccines can be stabilised in certain glassy materials, soluble in water. It has been proposed to form these glassy materials as a powder suspended in a non-aqueous liquid for injection into a patient. There is a problem in maintaining the suspension because the particles tend to sink to the bottom. The problem is solved by adding a blowing agent into a solution for which the glass is formed. The blowing agent decomposes as the solution evaporates thereby forming cavities in the resulting glass structure, reducing its density to match that of the liquid in which it is to be suspended. Other uses for the invention are in compositions intended for inhalation and for rapid dissolution in aqueous solutions immediately before use. | 08-20-2009 |
20080294100 | Pharmaceutical Device For the Administration of Substrates to Patients - Biological materials such as vaccines can be stabilised in certain glassy materials soluble in water. It has been proposed to form these glassy materials as a powder suspended in a non-aqueous liquid for injection into a patient. This method is complicated by the need to find suitable compatible liquids and to stop the glassy particles from congregating in liquid. These problems have been obviated by supporting the glassy material on a porous membrane remote from the eluant. When the biological material requires administration, the eluant can be passed across the membrane dissolving the glass and causing the substance to be carried by the liquid into the patient. | 11-27-2008 |