ALBERTA HEALTH SERVICES Patent applications |
Patent application number | Title | Published |
20150080704 | REDUCING ARTEFACTS IN MRI IMAGE DATA - A computer-implemented method is provided for reducing artefacts in an MRI image as a result of radiation induced current in collector coils of an MRI apparatus. The method comprises the following steps. Selecting a plurality of pixels in a k-space image prior to generation of the MRI image. Analysing each of the plurality of selected pixels to determine whether a pixel intensity is greater than a predefined global threshold. For each pixel having pixel intensity greater than the predefined global threshold, determining whether the pixel lies within a signal region of the k-space image or outside of the signal region of the k-space image. For each pixel that lies outside of the signal region, modifying the pixel intensity to be similar to a background pixel intensity, thereby creating a modified k-space image. Generating the MRI image based on the modified k-space image. A non-transitory computer readable medium and a radiation therapy system configured to implement the method are also provided. | 03-19-2015 |
20130267515 | COMBINATION COMPRISING AN ATP ANALOG AND AN ADENOSINE RECEPTOR ANTAGONIST OR A NUCLEOBASE/NUCLEOSIDE ANALOG FOR THE TREATMENT OF CANCER - A method for treating an ATP analog-induced side effect in a subject comprises administering an effective amount of an adenosine receptor antagonist to the subject. A method for treating cancer in a subject comprises administering a nucleobase and/or nucleoside prior to administering an ATP analog. | 10-10-2013 |
20130211066 | COMPOUNDS USEFUL IN IMAGING AND THERAPY - Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated 1-#-D-(5-deoxy-5-[I*]-iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated 1-#-D-(5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole (18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides. | 08-15-2013 |
20130200897 | METAMATERIAL LINERS FOR HIGH-FIELD-STRENGTH TRAVELING-WAVE MAGNETIC RESONANCE IMAGING - A liner for a bore of a waveguide is provided. The liner as an aperture passing through it and is formed of a metamaterial that has a relative electrical permittivity that is negative and near zero. When the liner is installed in the waveguide, it lowers the cutoff frequency of the waveguide while allowing the waveguide to remain hollow. This liner can be used in the bore of an MRI machine to lower the cutoff frequency of the bore of the MRI machine to allow the MRI machine to operate using waves having a lower frequency that if the liner was not used. | 08-08-2013 |
20130178515 | PREDICTIVE MARKERS FOR TAXANE RESPONSIVENESS AND METHODS OF USE THEREOF - Taxanes are widely used in the treatment of breast cancer, although there are currently no validated predictive markers for taxane responsiveness. While the mechanism by which taxanes induce mitotic arrest is well documented, the signaling pathway that links mitotic arrest to cell death, is ill-defined. As described herein, the BH3-only protein Bad and Bik are prognostic indicators for overall survival after adjuvant taxane chemotherapy and a predictive marker for taxane responsiveness. | 07-11-2013 |
20120142721 | SMALL MOLECULE INHIBITORS OF POLYNUCLEOTIDE KINASE/PHOSPHATASE, POLY(ADP-RIBOSE) POLYMERASE AND USES THEREOF - The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions. | 06-07-2012 |
20120069962 | REAL-TIME DOSE RECONSTRUCTION USING DYNAMIC SIMULATION AND IMAGE GUIDED ADAPTIVE RADIOTHERAPY - A radiation therapy treatment method comprises imaging a subject and simulating four-dimensional aspects of radiotherapy. A treatment plan based on the simulation is generated to permit real-time, three-dimensional dose reconstruction at the time of treatment. The simulation and treatment plan are used during treatment fractions to achieve real-time image guidance. | 03-22-2012 |