Agency For Science, Technology and Research Patent applications |
Patent application number | Title | Published |
20160109434 | SOLID SUPPORTED ARTIFICIAL CELL MEMBRANE SYSTEM - The present invention relates to an artificial cell membrane system comprising at least one membrane protein carrier associated with at least one membrane protein, wherein the at least one membrane protein carrier comprises or consists of a polymeric vesicle or a polymeric planar structure, and a solid support freely suspended in a fluid medium, wherein the at least one membrane protein carrier is attached to a surface of the solid support. A method of forming the artificial cell membrane system, and use of the artificial cell membrane system as a reagent are also provided. | 04-21-2016 |
20160106706 | METHOD OF DELIVERING AN ANTI-CANCER AGENT TO A CELL - There is provided a delivery vehicle comprising an anti-cancer agent together with a conjugate of a delivery agent containing a free aldehyde and a flavonoid, having the delivery agent conjugated at the C6 and/or the C8 position of the A ring of the flavonoid. The resulting delivery vehicles may be used to deliver an anti-cancer agent to a cell. | 04-21-2016 |
20160100361 | COMMUNICATION METHODS AND COMMUNICATION DEVICES - According to various embodiments, a communication method may be provided. The communication method may include at least one of sending a data unit or receiving a data unit. The data unit may include or may be a poll type field indicating one of a plurality of requests from a mobile radio communication device to an access point with respect to at least one of transmission of buffered data from the access point to the mobile radio communication device or a timing of communication between the access point and the mobile radio communication device. | 04-07-2016 |
20160090386 | Purine Diones As Wnt Pathway Modulators - The invention relates to the use of compounds of general structure (I) in modulation of the Wnt pathway [Formula should be inserted here] wherein R | 03-31-2016 |
20160088484 | SPECTRUM COORDINATION DEVICES, RADIO COMMUNICATION DEVICES, SPECTRUM COORDINATION METHODS, AND METHODS FOR CONTROLLING A RADIO COMMUNICATION DEVICE - According to various embodiments, a spectrum coordination device may be provided. The spectrum coordination device may include: a memory configured to store working channel information indicating for each radio communication device of a plurality of radio communication devices information of at least one channel used by the respective radio communication device; a radio communication device information receiver configured to receive working channel update information of at least one radio communication device of the plurality of radio communication devices; a conflict determination circuit configured to determine whether there is a conflict of channels to be used by the plurality of radio communication devices based on the working channel information and the working channel update information; and a working channel information updating circuit configured to update the working channel information based on the determination of the conflict determination circuit. | 03-24-2016 |
20160083690 | MICROCARRIERS FOR STEM CELL CULTURE AND FABRICATION THEREOF - A method for manufacturing polycaprolactone microcarriers is disclosed together with uses of the microcarriers. | 03-24-2016 |
20160076023 | METHOD FOR GENERATING EXTENDED SEQUENCE READS - The present invention provides an approach to increase the effective read length of commercially available sequencing platforms to several kilobases and be broadly applied to obtain long sequence reads from mixed template populations. A method for generating extended sequence reads of long DNA molecules in a sample, comprising the steps of: assigning a specific barcode sequence to each template DNA molecule in a sample to obtain barcode-tagged molecules; amplifying the barcode-tagged molecules; fragmenting the amplified barcode-tagged molecules to obtain barcode-containing fragments; juxtaposing the barcode-containing fragments to random short segments of the original DNA template molecule during the process of generating a sequencing library to obtain demultiplexed reads; and assembling the demultiplexed reads to obtain extended sequence reads for each DNA template molecule, is disclosed. Also disclosed are methods systems and software for assembling paired end sequence reads to produce extended reads. | 03-17-2016 |
20160040221 | IDENTIFICATION OF BIOLOGICALLY AND CLINICALLY ESSENTIAL GENES AND GENE PAIRS, AND METHODS EMPLOYING THE IDENTIFIED GENES AND GENE PAIRS - A method of obtaining cut-off expression values should be selected so as to maximise the separation of the respective survival curves of the two groups of patients. Pairs of genes are statistically significant genes are generated by generating a plurality of models, each of which represents a way of partitioning a set of subjects based on the optimal cut-off expression values of the pair of genes. Those gene pairs are identified for which one of the models has a high prognostic significance. Novel survival significant gene sets forming functional modules which could be used to develop specific prognostic and predictive tests are derived. | 02-11-2016 |
20160002605 | CHROMATOGRAPHIC PURIFICATION OF VIRUS PREPARATIONS WITH NEGATIVELY CHARGED PARTICLES - A method of purifying a sample that includes a desired virus includes the steps of (i) providing a packed chromatographic column having negatively charged porous particles, (ii) equilibrating the column to the conditions to which the desired virus in the sample is to elute, (iii) contacting the sample with the packed chromatographic column such that the sample volume applied to the packed chromatographic column is less than or equal to the interparticle space of the negatively charged porous particles within the packed chromatographic column, (iv) eluting the desired virus from the packed chromatographic column, where the desired virus is in a purer state and in the conditions to which the packed chromatographic column was equilibrated. | 01-07-2016 |
20160000757 | METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS - There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts. | 01-07-2016 |
20150382283 | Access Points, Radio Communication Devices, Methods for Controlling an Access Point, and Method for Controlling a Radio Communication Device - According to various embodiments, an access point may be provided. The access point may include: a transmitter configured to transmit restricted access window parameters. The restricted access window parameters may include at least one parameter selected from a list of parameters consisting of: a type parameter indicating which type of restricted access window parameters is represented by the restricted access window parameters; a same group indicator parameter indicating whether a group field is present; and a channel indication presence parameter indicating whether a channel indication is present. | 12-31-2015 |
20150376231 | PROTEIN PURIFICATION METHODS - A method for the purification of a desired protein from a protein preparation includes conditioning the protein preparation by treatment with soluble organic multivalent ions, immobilized organic multivalent ions, or both, optionally in the presence of supersaturated allantoin, thereby removing at least 90% of chromatin, then (1) precipitating the desired protein with a nonionic organic polymer in the presence of non-protein-precipitating salts at greater than physiological concentration to provide a precipitate of the desired protein; or (2) precipitating the desired protein with a nonionic organic polymer in the absence of non-precipitating salts at greater than physiological concentration to provide a precipitate and subsequently washing the precipitate with a nonionic organic polymer in the presence of non-protein-precipitating salts at greater than physiological concentration. | 12-31-2015 |
20150371697 | Magnetoresistive Device and a Writing Method for a Magnetoresistive Device - According to embodiments of the present invention, a magnetoresistive device is provided. The magnetoresistive device includes at least two ferromagnetic soft layers, wherein the at least two ferromagnetic soft layers have different ranges of magnetization switching frequencies. Further embodiments provide a magnetoresistive device including at least two oscillating ferromagnetic structures, wherein ranges of operating current amplitudes at which oscillations are induced for the at least two oscillating ferromagnetic structures are different. According to further embodiments of the present invention, writing methods for the magnetoresistive devices are provided. | 12-24-2015 |
20150368406 | BIODEGRADABLE AND BIOCOMPATIBLE SHAPE MEMORY POLYMERS - This invention relates to shape memory block copolymers comprising: at least one switching segment having a T | 12-24-2015 |
20150359843 | P53 ACTIVATING PEPTIDES - The present invention is directed to p53 activating peptides. The present further describes methods for generating these peptides and the use of these peptides. | 12-17-2015 |
20150352220 | SELF-ASSEMBLING ULTRASHORT PEPTIDES MODIFIED WITH BIOACTIVE AGENTS BY CLICK CHEMISTRY - The present invention relates to hydrogels comprising a first peptide with a covalently linked bioactive agent and optionally a second peptide. The present invention further relates to uses of the hydrogel for delivery of the bioactive agent or as an implant. The present invention further relates to drug delivery devices, implant, pharmaceutical or cosmetic compositions comprising the hydrogel. The present invention further relates to methods of local treatment of diseases and to methods for preparing the first peptide and the hydrogels. | 12-10-2015 |
20150344547 | MONOCLONAL ANTIBODY AGAINST MURAMYL PEPTIDES - Disclosed is an isolated antibody or an antigen-binding fragment thereof. The antibody is capable of binding to a muramyl peptide, or a derivative or an analog or a salt thereof. The muramyl peptide comprises muramic acid and an amino acid selected from the group consisting of alanine, isoglutamine, glutamic acid, and a salt thereof. Also disclosed are methods of producing the antibody, compositions comprising the antibody, methods of treating using the antibody, uses of the antibody, methods of detecting muramyl peptide, an assay for detecting muramyl peptide, an antibacterial agent, hybridomas and kits. | 12-03-2015 |
20150342984 | ANTIMICROBIAL CATIONIC POLYAMINES - Antimicrobial, non-hemolytic cationic polyamines were prepared by treating partially N-acylated polyethylenimines and/or partially oxidized polyethylenimines with a protic acid. The cationic polyamines can have a linear or branched polyethylenimine backbone structure. Preferably, the cationic polyamines comprise pendant urea groups, which can be introduced via a cyclic carbonate comprising a pendant urea group. The cationic polyamines can be active against a tuberculosis | 12-03-2015 |
20150339458 | SYSTEM AND METHOD FOR DERIVING PARAMETERS FOR HOMEOSTATIC FEEDBACK CONTROL OF AN INDIVIDUAL - A method and system of deriving a physiological homeostatic operating set point of an individual comprising the steps of: obtaining a dataset of predetermined number of homeostatic measurements of the individual; fitting the dataset of predetermined number of homeostatic measurements according to a negative exponential decay function; identifying and setting the physiological homeostatic operating set point unique to the individual as the point corresponding to the point of maximum curvature on the fitted negative exponential decay function is disclosed. The method is especially suited for determining the [FT4]-[TSH] set point, which is unique for each individual. | 11-26-2015 |
20150318956 | Radio Communication Devices, Access Points, Method for Controlling a Radio Communication Device, and Methods for Controlling an Access Point - According to various embodiments, a radio communication device may be provided. The radio communication device may include: a transmitter configured to transmit a null data packet. The null data packet may include acknowledgement data indicating acknowledgements for a plurality of packets. The null data packet may include a cyclic redundancy check field configured to provide information based on which the null data packet or acknowledgements may be checked for errors. The null data packet may include further information based on which the acknowledgements may be checked for errors. | 11-05-2015 |
20150313869 | FLAVONOID HYDROGEL - There is provided methods for producing a hydrogel comprising conjugates of a hydrogel forming agent and a flavonoid including a method for producing a hydrogel that is capable of adhesion of cells and which comprises enzymatically cross-linked conjugates of a hydrogel forming agent and a flavonoid. There is also provided a method for producing a hydrogel comprising conjugates of a hydrogel forming agent and a flavonoid without the addition of an exogenous peroxide or peroxidase or without the addition of an exogenous peroxide. Hydrogels produced by such methods and methods of using the hydrogels are also described herein. | 11-05-2015 |
20150306196 | POLYPEPTIDE VACCINE - We provide a polypeptide vaccine for treatment and prevention of cancer, particularly prevention of metastasis of cancer. Also provided are methods of treating or preventing cancer, and pharmaceutical compositions comprising the polypeptide vaccine. | 10-29-2015 |
20150304777 | TRANSDUCER AND METHOD OF CONTROLLING THE SAME - According to embodiments of the present invention, a transducer is provided. The transducer includes a substrate, and a diaphragm suspended from the substrate, wherein the diaphragm is displaceable in response to an acoustic signal impinging on the diaphragm, wherein the transducer is configured, in a first mode of operation, to determine a direction of the acoustic signal based on a first displacement of the diaphragm in the first mode of operation, and to decide to accept or reject the acoustic signal based on at least one predetermined parameter and the determined direction of the acoustic signal, and in a second mode of operation, to sense the acoustic signal based on a second displacement of the diaphragm in the second mode of operation if the acoustic signal is accepted in the first mode of operation. | 10-22-2015 |
20150296532 | Access Points, Radio Communication Devices, Methods for Controlling an Access Point, and Methods for Controlling a Radio Communication Device - According to various embodiments, an access point may be provided. The access point may include: a transmitter configured to transmit scheduling information for a page. The page may include one or more segments of a Traffic Indication Map (TIM). The scheduling information may include at least one of the following information: an explicit indication of an interval of one or more recurrences of subsequent transmissions of the scheduling information for the page; or information indicating scheduling of transmission of segments of the page including at least: an offset between the transmission of the first segment included in the page scheduling and the transmission of the scheduling information; and the number of blocks in each segment of the page, wherein a block contains a predetermined number of bits of the TIM. | 10-15-2015 |
20150282695 | ENDOSCOPES - In various embodiments of the present disclosure, there is provided an endoscope including: an elongate shaft body; an optical scope provided within the elongate shaft body, the optical scope comprising an optical aperture provided at the distal end of the optical scope, corresponding to a distal end of the elongate shaft body; an aperture cover provided at the distal end of the elongate shaft body for shielding the optical aperture from debris external to the elongate shaft body; and an actuation system provided at a proximal end of the elongate shaft body; wherein the actuation system drives the aperture cover to rotate. | 10-08-2015 |
20150276711 | METHOD AND SYSTEM FOR IN VITRO DEVELOPMENTAL TOXICITY TESTING - A method and system of in vitro developmental toxicity testing comprising the steps of micropatterning an extracellular matrix; growing embryonic stem cells on the micropatterned extracellular matrix in the presence of mesoendermal induction and testing for change of the geometrical mesoendoderm structure in the presence or absence of a test compound wherein (1) a decrease in mesoendodermal differentiation and/or (2) a change in morphology of the geometrical mesoendoderm structure in the presence of the test compound compared to cells in the absence of the test compound indicates that the test compound is a developmental toxic agent. | 10-01-2015 |
20150275300 | BIOMARKERS FOR DOWN SYNDROME PRENATAL DIAGNOSIS - Disclosed is an isolated biomarker/biomarker region. Also disclosed are isolated biomarker/biomarker regions for detecting trisomy 21, methods of determining the likelihood of a foetus to suffer from a specific disease using the biomarker/biomarker region, a kit and a method of determining the methylation levels of a biomarker/biomarker region. | 10-01-2015 |
20150274789 | COMPOUNDS AND METHODS FOR THE PRODUCTION OF SUCKERIN AND USES THEREOF - Sucker ring tooth (SRT) proteins called Suckerins were identified from the sucker tissue of three distantly related Decapodiformes species. These proteins assemble into silk-like beta-sheet reinforced materials. The use of suckerin proteins to produce fibres, films and tissue scaffolds is also described. | 10-01-2015 |
20150267259 | METHOD OF PROGNOSIS AND STRATIFICATION OF OVARIAN CANCER - A method for the prognosis of overall survival or prediction of therapeutic outcome for a patient suffering from epithelial ovarian cancer (EOC), comprising: a. providing a metabolism response sample from the patient, b. determining the expression level of microRNA family lethal-7b (let-7b) in the sample; c. using the expression level of the let-7b to obtain the prognosis of overall survival or prediction of therapeutic outcome for the patient. | 09-24-2015 |
20150264932 | 1,3,6-DIOXAZOCAN-2-ONES AND ANTIMICROBIAL CATIONIC POLYCARBONATES THEREFROM - Eight-membered ring cyclic carbonates comprising a ring nitrogen at position 6 (1,3,6-dioxazocan-2-ones) were prepared by reaction of precursor diols with active carbonates. The ring nitrogen is linked to a pendant group Y′ via a methylene linking group. The cyclic carbonates undergo organocatalyzed ring opening polymerization to form an initial polycarbonate comprising a backbone tertiary amine group. Quaternization of the initial polycarbonates forms cationic polycarbonates comprising a positive-charged backbone quaternary nitrogen. The cationic polycarbonates can be potent antimicrobial agents. | 09-24-2015 |
20150255547 | III-Nitride High Electron Mobility Transistor Structures and Methods for Fabrication of Same - Structures for III-nitride GaN high electron mobility transistors (HEMT), method for fabricating for GaN devices and integrated chip-level power systems using the GaN devices are provided. The GaN HEMT structure includes a substrate, an AlGaN/GaN heterostructure grown on the substrate, and a normally-off GaN device fabricated on the AlGaN/GaN heterostructure. The AlGaN/GaN heterostructure includes a GaN buffer layer and an AlGaN barrier layer. The integrated chip-level power system includes a substrate, an AlGaN/GaN heterostructure layer grown on the substrate and a plurality of GaN devices. The AlGaN/GaN heterostructure layer includes a GaN buffer layer and an AlGaN barrier layer and is formed into mesa areas and valley areas. Each of the plurality of GaN devices are fabricated on a separate one of the mesa areas. | 09-10-2015 |
20150255135 | MAGNETOELECTRIC DEVICE, METHOD FOR FORMING A MAGNETOELECTRIC DEVICE, AND WRITING METHOD FOR A MAGNETOELECTRIC DEVICE - A magnetoelectric device is provided. The magnetoelectric device includes a reference magnetic layer structure having a fixed magnetization orientation, and a synthetic antiferromagnetic layer structure including a free magnetic layer structure and a coupling magnetic layer structure antiferromagnetically coupled to each other, each of the free magnetic layer structure and the coupling magnetic layer structure having a magnetization orientation that is variable, wherein the reference magnetic layer structure and the synthetic antiferromagnetic layer structure are arranged one over the other. According to further embodiments of the present invention, a method for forming a magnetoelectric device and a writing method for a magnetoelectric device are also provided. | 09-10-2015 |
20150250854 | VOLTAGE GATED CALCIUM CHANNEL BETA-SUBUNIT ANCHORING REGULATOR PROTEIN AND USES THEREOF - The present invention relates to a novel gene encoding a protein termed voltage gated calcium channels β subunit anchoring regulator protein (VDCC BARP) or a peptide fragments thereof. The present invention also relates to the use of VDCC BARP in modulation of voltage gated calcium channels via altering the concentration of VDCC BARP or a peptide fragments thereof. | 09-10-2015 |
20150250001 | CIRCUIT ARRANGEMENT AND METHOD OF DETERMINING A PRIORITY OF PACKET SCHEDULING - The present invention is a circuit arrangement for a wireless cellular network. The circuit arrangement includes a determiner configured to determine a priority value of each packet of a plurality of packets based on at least a position of a video frame in a group of pictures and a type of the video frame, the video frame or a part thereof being contained in the packet, wherein the type of video frame comprises I frame data or P frame data; and wherein the determiner is further configured to set the priority value of a packet including I frame data lower than the priority value of at least one other packet including P frame data; and a controller configured to control scheduling of the packet based on the determined priority value for a communication device in a wireless cellular network. A method of determining a priority of packet scheduling is also disclosed. | 09-03-2015 |
20150249529 | COMMUNICATION METHODS AND COMMUNICATION DEVICES - According to various embodiments, a communication method may be provided. The communication method may include: at least one of sending a first data unit including a physical layer (PHY) header or receiving a first data unit including a PHY header. The PHY header may include at least a field to indicate whether a response data unit is intended to follow the first data unit, and to indicate the type of the response data unit, when a response data unit is intended to follow the first data unit. The type of the response data unit may be used to estimate the duration of the response data unit. | 09-03-2015 |
20150244619 | COMMUNICATION METHODS AND COMMUNICATION DEVICES - According to various embodiments, a communication method may be provided. The communication method may include: at least one of sending a data unit or receiving a data unit; wherein the data unit is a null-data packet (NDP) and includes at least a physical layer (PHY) header; wherein the PHY header includes a plurality of fields; and wherein the plurality of fields include a sub-type field with at least 3 bits indicating a NDP sub-type of the data unit. | 08-27-2015 |
20150244369 | Circuit Arrangements and Methods of Operating the Same - In various embodiments, a circuit arrangement may be provided. The circuit arrangement may include a level shifting stage configured to be coupled to a first reference voltage, the level shifting stage having an output node. The circuit arrangement may further include a first input electrode in electrical connection with the level shifting stage. The circuit arrangement may also include a second input electrode in electrical connection with the level shifting stage. The circuit arrangement may further include a load having a first end and a second end, the first end coupled to the level shifting stage and the second end for coupling to a second reference voltage. In addition, the circuit arrangement may include a bypass circuit element connected in parallel to the load. The bypass circuit element may be configured to allow current to flow through upon application of an external voltage for bypassing the load. | 08-27-2015 |
20150231226 | NOVEL ATTENUATED DENGUE VIRUS STRAINS FOR VACCINE APPLICATION - The present invention discloses a method of eliciting an immune response and a method of vaccination comprising administration of a mutated flavivirus. The mutated flavivirus comprises at least one mutation in a nucleic acid sequence encoding for the non-structural protein 5 of the flavivirus sequence resulting in inactivation of the 2′O-methyltransferase. | 08-20-2015 |
20150225454 | TETRABRANCHED PEPTIDES AND ANALOGUES AS A NEW CLASS OF ANTIMICROBIALS AND THEIR PREPARATION THEREOF - An isolated peptide tetramer includes the formula [(RGRKVVRR) | 08-13-2015 |
20150209308 | METHODS TO INHIBIT INTRACELLULAR GROWTH OF BACTERIA AND TO TREAT BACTERIA-MEDIATED DISEASES - Disclosed is a method of preventing, treating or inhibiting bacterial infections. The method comprises administering at least one of the compounds disclosed herein. Also disclosed are methods of increasing acidity of bacterial phagosomes to inhibit bacterial growth, methods of increasing mitochondrial reactive oxygen species (mROS) generation to inhibit bacterial growth in a cell, pharmaceutical compositions and uses thereof. | 07-30-2015 |
20150197725 | Method of Deriving Mesenchymal Stem Cells - We describe a method of obtaining a cell culture, the method comprising providing a cell obtained by dispersing a human embryonic stem cell (hESC) colony, or a descendent thereof, and propagating the cell in the absence of a feeder cell layer in a serum free medium comprising FGF2 and optionally PDGF AB. Preferably, the human embryonic stem cell (hESC) colony is dispersed with a dispersing agent which is trypsin. | 07-16-2015 |
20150190587 | VASCULAR ACCESS DEVICE AND GUIDING PORTION - According to various embodiments, a method and system to obtain access to a blood vessel underneath a skin layer that may preserve lifespan of the blood vessel and reduce executional skill variability may be provided. The method includes placing a guiding portion between the blood vessel and the skin layer; and configuring the guiding portion to receive and guide a needle to reach the same location of the blood vessel repeatedly and consistently; and forming a resultant scarred track between the blood vessel and the skin layer as the guiding portion is resorbed over time. The system includes a vascular access device configurable to first possess strength to penetrate through a tissue layer, subsequently possess flexibility to conform to the surrounding tissue beneath the tissue layer; and a guiding portion which may be resorbable, wherein the inlet includes a larger diameter compared to the outlet. | 07-09-2015 |
20150183703 | SYNTHESIS OF DIACIDS - The invention relates to a process for preparing a dicarboxylic acid comprising the steps: (a) heating a lactone in the presence of a first catalyst system to produce an alkenoic acid; and (b) contacting the alkenoic acid with carbon monoxide, water and a second catalyst system to produce a reaction composition comprising the second catalyst system and the dicarboxylic acid. | 07-02-2015 |
20150182468 | STIMULI-RESPONSIVE INTERPOLYMER COMPLEX COATED HOLLOW SILICA VESICLES - A porous hollow silica particle with an interpolymer complex immobilized thereon is provided. The interpolymer complex comprises a first polymer immobilized to a surface of the silica particle, and a second polymer complexed with the first polymer. Pharmaceutical compositions comprising the silica particle, and methods of forming the silica particle are also provided. | 07-02-2015 |
20150157723 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY - Nanoparticles comprise a drug, a first block polymer and a second block polymer. The first block polymer has a poly(ethylene oxide) (PEO) block and a polycarbonate block bearing a side chain aromatic nitrogen-containing heterocycle (N-heterocycle). The N-heterocycle can be in the form of a base, a hydrosalt of the base, a sulfobetaine adduct of the base, or a combination thereof. The second block polymer has a PEO block and a polycarbonate block bearing a side chain catechol group, which can be present as a catechol, oxidized form of a catechol, and/or a polymerized form of a catechol. The nanoparticles can be dispersed in water and are capable of controlled release of the drug. | 06-11-2015 |
20150154468 | METHOD AND DEVICE FOR IMAGE PROCESSING - Embodiments provide a method for processing an input image having a plurality of pixels, wherein each pixel has a pixel position. The method may include determining, for each pixel position, a vector based on the input image; and determining, for each pixel position, a detail value for the pixel position based on the determined vectors at a plurality of neighboring pixel positions within a predetermined neighboring block of the pixel position. | 06-04-2015 |
20150149873 | ERROR CORRECTION METHOD AND MODULE FOR NON-VOLATILE MEMORY - There is provided an error correction method for a non-volatile memory. The method includes receiving a codeword read from the non-volatile memory, computing a reliability information for each bit of the codeword received, and performing a reduced-complexity soft-decision decoding (SDD) technique to decode the received codeword. In particular, the SDD technique includes forming a set of test patterns based on the reliability data, and determining whether to perform a HDD of a test pattern in the set of test patterns based on a distance between the test pattern and a candidate pattern. There is also provided an error correction module for a non-volatile memory and a memory system incorporating the error correction module. | 05-28-2015 |
20150146322 | DATA STORAGE DEVICE - According to an embodiment of the present invention, a data storage device comprising a motor having a stator is disclosed. The stator may include a substrate having a first surface and a second surface opposite to the first surface; and a n-phase winding arrangement having n phase windings; wherein each phase winding comprises m flat fractional-pitch coils arranged on the first surface of the substrate such that the coils are spaced apart uniformly along a closed loop and connected in series; wherein each coil together with an angular section of the substrate between the coil and an adjacent coil of the same phase winding defines a stator pole-pair; and wherein m is an integer larger than 1. | 05-28-2015 |
20150145374 | TRANSDUCER AND METHOD FOR FORMING THE SAME - A transducer is provided, which includes a substrate, wherein a cavity is defined at least partially through the substrate, at least one stopper structure arranged within the cavity, a support layer arranged over the at least one stopper structure and the cavity to seal the cavity, and a piezoelectric functional arrangement arranged on the support layer. According to further embodiments of the present invention, a method for forming a transducer is also provided. | 05-28-2015 |
20150137015 | CONNECTOR FOR MICROFLUIDIC DEVICE, A METHOD FOR INJECTING FLUID INTO MICROFLUIDIC DEVICE USING THE CONNECTOR AND A METHOD OF PROVIDING AND OPERATING A VALVE - A connector for being inserted into a first channel of a microfluidic device. The connector includes a first end and a second end, when seen in the direction of a longitudinal central axis of said connector, wherein the second end is arranged in a second end portion of the connector; an inner hollow space; a outer circumferential wall extending around said longitudinal central axis, such that said outer circumferential wall extends around said inner hollow space. The outer circumferential wall has at least two different outer diameters along said longitudinal central axis, which outer diameters differ in their value; and the outer surface of said circumferential wall is rotationally symmetrical with regard to said longitudinal central axis; an opening provided in said first end for receiving an insert and, being in fluid connection with said inner hollow space; and a membrane sealingly covering said inner hollow space towards said second end of the connector, wherein the insert is configured to provide pressure on said membrane. | 05-21-2015 |
20150133685 | PROCESS TO PRODUCE A DIENE FROM A LACTONE - The invention provides a process for the production of a diene. In the process, a lactone is heated in the presence of a first catalyst system to produce an alkene and carbon dioxide and the alkene is contacted with a second catalyst system to produce an alkyldiene. | 05-14-2015 |
20150132748 | INTEGRATED MICROFLUIDIC AND SOLID STATE PYROSEQUENCING SYSTEMS - The invention provides for sequencing a nucleic acid molecule based on the detection of base incorporation by the release of pyrophosphate (PPi) using a new enzyme system comprising adenosine diphosphate (ADP)-glucose pyrophosphorylase (AGPase) and its substrate ADP-glucose. | 05-14-2015 |
20150132475 | METHOD FOR PREPARING A LEAD-FREE PIEZOELECTRIC THIN FILM - The present invention discloses a method of preparing a lead-free piezoelectric thin film comprising the steps of: providing a precursor solution comprising at least one alkali metal ion, a polyamino carboxylic acid, and an amine; depositing the precursor solution on a substrate to form a film; and annealing the film. The present invention also provides a lead-free piezoelectric thin film prepared according to the method, a precursor solution for use in the method and a method of preparing the precursor solution. | 05-14-2015 |
20150119558 | CHO-GMT RECOMBINANT PROTEIN EXPRESSION - The present invention provides modified cells for producing proteins with modified glycosylation patterns. Proteins produced in such cells, and the use of such proteins in medicine, and particularly in the treatment of cancer, is also provided. | 04-30-2015 |
20150118728 | APPARATUS AND METHOD FOR SEPARATING A BIOLOGICAL ENTITY FROM A SAMPLE VOLUME - According to embodiments of the present invention, an apparatus for separating a biological entity from a sample volume is provided. The apparatus includes an input chamber including an inlet configured to receive the volume sample, and an outlet, at least one magnetic element adjacent a portion of the input chamber, the magnetic element configured to provide a magnetic field in a vicinity of the portion of the input chamber to trap at least some leukocytes from the sample volume, and a filter in fluid communication with the outlet, the filter configured to separate the biological entity. According to further embodiments of the present invention, a method for separating a biological entity from a sample volume is also provided. | 04-30-2015 |
20150098976 | ANTIMICROBIAL AND ANTIFOULING CATECHOL-CONTAINING POLYCARBONATES FOR MEDICAL APPLICATIONS - Catechol-bearing polycarbonates (catechol polymers) were prepared comprising i) a catechol repeat unit comprising a side chain catechol group, ii) a cationic repeat unit comprising a side chain cationic group selected from the group consisting of quaternary amine groups, quaternary phosphine groups, and combinations thereof, and iii) a PEG repeat unit comprising a side chain poly(ethylene oxide) group having a degree of polymerization of about 5 to about 30. The catechol polymers form antimicrobial and antifouling films on a variety of substrate surfaces, in particular silicone rubber. | 04-09-2015 |
20150098962 | MODULATORS OF CANDIDA HYPHAL MORPHOGENESIS AND USES THEREOF - The invention relates to modulation of fungal morphology between yeast-to-hyphal growth transition by controlling muramyl-L-alanine concentration and uses thereof. | 04-09-2015 |
20150098951 | MODULATORS OF CANDIDA HYPHAL MORPHOGENESIS AND USES THEREOF - The invention relates to modulation of fungal morphology between yeast-to-hyphal growth transition by controlling muramyl-L-alanine concentration and uses thereof. | 04-09-2015 |
20150092697 | METHODS FOR DETERMINING INFORMATION ABOUT A COMMUNICATION PARAMETER AND COMMUNICATION DEVICES - According to various embodiments, a method for determining information about a communication parameter may be provided. The method may include providing information about the communication parameter in at least one of an add block acknowledgement request signal, an acknowledgement signal for an add block acknowledgement request signal, an add block acknowledgement response signal, or an acknowledgement signal for an add block acknowledgement response signal. | 04-02-2015 |
20150079499 | PARTICLE EXHIBITING CATALYTIC ACTIVITY - A particle exhibiting catalytic activity comprising (a) an inner core formed of an alloy material; and (b) an outer shell formed of a metal material surrounding the inner core, wherein the alloy material is selected such that the inner core exerts a compressive strain on the outer shell. | 03-19-2015 |
20150076049 | MICROFILTER AND APPARATUS FOR SEPARATING A BIOLOGICAL ENTITY FROM A SAMPLE VOLUME - According to embodiments of the present invention, a microfilter is provided. The microfilter includes a first porous layer and a second porous layer arranged one over the other, wherein the first porous layer includes a plurality of first pores defined through the first porous layer, wherein the second porous layer includes a plurality of second pores defined through the second porous layer, and wherein one or more respective second pores are arranged to at least substantially overlap with each respective first pore such that a respective opening defined between a perimeter of the each respective first pore and a perimeter of each of the one or more respective second pores is smaller than a diameter of each first pore. According to further embodiments of the present invention, an apparatus for separating a biological entity from a sample volume is also provided. | 03-19-2015 |
20150057470 | METHOD FOR SYNTHESIZING A SUGAR ALCOHOL - A method for synthesizing a sugar alcohol comprising the step of hydrolyzing a polysaccharide in the presence of hydrogen ions (H | 02-26-2015 |
20150055242 | METHOD AND SYSTEM FOR ESTIMATING THE POSITION ERROR SIGNAL (PES) METRIC FOR A MAGNETIC STORAGE SYSTEM - A method and system for estimating the position error signal (PES) metric for a magnetic storage system. The method comprises the steps of reading multiple readback tracks from a storage medium of the magnetic storage system using respective readers of a multiple reader head positioned at or near a data track of interest; employing an adaptive SMR equalizer to equalize the signals from the multiple read head; and extracting information from the adaptive SMR equalizer sub-filters as an estimate of the PES metric. | 02-26-2015 |
20150052963 | METHOD AND APPARATUS FOR FORGING - An apparatus ( | 02-26-2015 |
20150038506 | BICYCLIC HETEROARYL DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF - The present invention relates to certain compounds (e.g., imidazopyrazine, imidazopyridine, imidazopyridazine and imidazpyrimidine compounds) that act as inhibitors of the MAP kinase interacting kinases MNK2a, MNK2b, MNK1a, and MNK1b. The present invention further relates to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the preparation of a medicament for the prophylaxis and treatment of diseases (e.g., proliferative diseases (e.g., cancer), neurodegenerative diseases (e.g., Alzheimer's disease), metabolic diseases (e.g. diabetes), neurodevelopmental disorders (e.g. autism), or psychiatric disorders (e.g. schizophrenia or anxiety)) as well as methods of treating these diseases. | 02-05-2015 |
20150037390 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY - Cationic, anionic, and/or zwitterionic bis-urea compounds self-assemble by non-covalent interactions in aqueous solution to form high aspect ratio nanofibers. The nanofibers reversibly bind drugs by non-covalent interactions, forming drug compositions for exhibiting sustained release of the drug. | 02-05-2015 |
20150037248 | IL-1beta NEUTRALIZING HUMAN MONOCLONAL ANTIBODIES - The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production. | 02-05-2015 |
20150034242 | SCAFFOLD AND METHOD OF FORMING SCAFFOLD BY ENTANGLING FIBRES - A porous scaffold is provided, which comprises tangled fibres. A porous scaffold can be formed by applying a fluid to fibres to entangle them. The fibres comprise a polyelectrolyte complex and a cross-linker. The cross-linker links polyelectrolytes within individual fibres and inhibits secondary polyelectrolyte complication between adjacent fibres. | 02-05-2015 |
20150031748 | MODULATING THE INTERACTION BETWEEN ZO-2/TJP2 AND A SNAIL ZINC FINGER TRANSCRIPTION FACTOR FAMILY MEMBER - There is provided a method of identifying candidate agents capable of modulating interaction between a first polypeptide and a second polypeptide, wherein the first polypeptide is ZO-2/TJP2 or a functional variant thereof and the second polypeptide is a Snail zinc finger transcription factor family member or a functional variant thereof. | 01-29-2015 |
20150031039 | METHODS AND DEVICE TO BALANCE RADIATION TRANSFERENCE - A method and device for adjusting the temperature of a sample by heating a substrate with a laser diode light; said light projected on to the substrate to absorb the light and convert the light energy to a heat energy thereby raising the temperature of the substrate corresponding to the intensity of the light energy, the substrate configured to transfer the thermal energy substantially homogenously to the sample. The device or method suitable for amplification of a nucleic acid sample. | 01-29-2015 |
20150030036 | COMPRESSION DEVICES, DECOMPRESSION DEVICES, COMPRESSION METHODS, AND DECOMPRESSION METHODS - The present invention is directed to a compression device including an identifier determination circuit configured to determine a first identifier value identifying a first communication terminal of a network, and a second identifier value identifying a second communication terminal of the network; a differential determination circuit configured to determine a differential value based on a difference between the first identifier value and the second identifier value; and a compressed string generation circuit configured to insert the differential value into a compressed string. A compression method, a decompression device and a decompression method are also disclosed. | 01-29-2015 |
20150029922 | STATIONS, ACCESS POINTS, COMMUNICATION SYSTEMS AND METHODS OF CONTROLLING THE SAME - In various embodiments, a method of controlling a station may be provided. The method may include receiving a first signal from an access point, the first signal including information indicating a time period. The method may further include deactivating the station after receiving the first signal and before expiry of the time period. The method may also include activating the station upon expiry of the time period. | 01-29-2015 |
20150029844 | METHOD AND A COMMUNICATION TERMINAL FOR MODULATING A MESSAGE FOR TRANSMISSION IN A WIRELESS COMMUNICATION NETWORK - The present invention is directed to a communication terminal in a wireless communication network. The communication terminal includes a receiver configured to receive a first message comprising a media access control (MAC) frame at a first transmission rate from a communication device in the wireless communication network; a message generator configured to generate a second message in response to the received first message, the second message comprising a control response frame; and a transmitter configured to transmit the control response frame at a second transmission rate, wherein the second transmission rate is lower than or equal to the first transmission rate; and wherein the second transmission rate is dependent on a difference in qualities between downlink communication and uplink communication between the communication device and the communication terminal. Methods of modulating a message for transmission in the wireless communication network are also disclosed. | 01-29-2015 |
20150025892 | METHOD AND SYSTEM FOR TEMPLATE-BASED PERSONALIZED SINGING SYNTHESIS - A system and method for speech-to-singing synthesis is provided. The method includes deriving characteristics of a singing voice for a first individual and modifying vocal characteristics of a voice for a second individual in response to the characteristics of the singing voice of the first individual to generate a synthesized singing voice for the second individual. In one embodiment the method includes deriving a template of first speech characteristics and first singing characteristics in response to a first individual's speaking voice and singing voice and extracting second speech characteristics from a second individual's speaking voice, then modifying the second speech characteristics in accordance with the template to generate the second individual's approximated singing voice and aligning acoustic features of the second individual's approximated singing voice in response to the first speech characteristics, the first singing characteristics and the second speech characteristics to generate the second individual's synthesized singing voice. | 01-22-2015 |
20150015102 | MOTOR AND A METHOD OF ASSEMBLING THE SAME - In various embodiments, a motor may be provided. The motor may include a base, a first rotor, a second rotor and a stator arranged between the first rotor and the second rotor, the stator including an alignment member for aligning the stator to the base. | 01-15-2015 |
20140374268 | METHOD FOR FORMING A COMPOSITE FILM - According to embodiments of the present invention, a method for forming a composite film is provided. The method includes providing a nanowire forming template, forming a plurality of nanowires through the nanowire forming template, removing material from a partial portion of the nanowire forming template to expose a portion of the plurality of nanowires, and forming a polymeric film between the plurality of nanowires to form a composite film. | 12-25-2014 |
20140371199 | BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF - The present invention relates to certain compounds (e.g., imidazopyrazine, imidazopyridine, imidazopyridazine and imidazpyrimidine compounds) that act as inhibitors of the MAP kinase interacting kinases MNK2a, MNK2b, MNK1a, and MNK1b. The present invention further relates to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the preparation of a medicament for the prophylaxis and treatment of diseases (e.g., proliferative diseases (e.g., cancer), inflammatory diseases, Alzheimer's disease), as well as methods of treating these diseases. | 12-18-2014 |
20140368079 | MOTOR AND METHOD FOR ASSEMBLING THE SAME - Embodiments provide a method for assembling a motor. The method may include providing a first rotor, a second rotor and a stator; and assembling the first rotor, the second rotor and the stator such that the stator is arranged between the first rotor and the second rotor. | 12-18-2014 |
20140362952 | Frequency Shift Keying Transmitter - According to embodiments of the present invention, a frequency shift keying transmitter is provided. The frequency shift keying transmitter includes a logic gate arrangement that produces an output signal having a frequency that depends on input signals to the logic gate arrangement, a clock generator coupled to the logic gate arrangement, the clock generator adapted to produce a clock signal, and a sampling arrangement coupled to the logic gate arrangement, the sampling arrangement adapted to receive a data signal, wherein the sampling arrangement is configured to sample the clock signal to generate periodic waveforms delayed from each other by an interval determined by the point the clock signal is sampled, wherein the sampling arrangement is configured to be controlled by the data signal to have the logic gate arrangement select periodic waveforms that are delayed from each other by one of a set of intervals associated with the data signal, to be used as the input signals to the logic gate arrangement to produce the output signal. | 12-11-2014 |
20140357878 | METHOD OF PRODUCING 5-HYDROXYMETHYLFURFURAL FROM CARBOHYDRATES - Disclosed herein is a process for preparing 5-hydroxymethylfurfural comprising the step of contacting a carbohydrate and a Brønsted acid in an alcoholic solvent comprising an alcohol selected from the group consisting of secondary alcohols, tertiary alcohols, aryl alcohols and combinations thereof under conditions to dehydrate the carbohydrate thereby forming a reaction product containing 5-hydroxymethylfurfural. | 12-04-2014 |
20140349933 | SELF-ASSEMBLED COMPOSITE ULTRASMALL PEPTIDE-POLYMER HYDROGELS - The present invention relates to composite hydrogels comprising at least one non-peptidic polymer and at least one peptide having the general formula: Z—(X) | 11-27-2014 |
20140349918 | DERIVATIVES OF XANTHONE COMPOUNDS - The present invention relates to xanthone analogs. Such compounds may be used in the treatment of bacterial infections. | 11-27-2014 |
20140349321 | BINDING MOLECULES AGAINST DENGUE VIRUS AND USES THEREOF - The present invention relates to binding molecules suited to the diagnosis, prevention and/or treatment of dengue virus infection. | 11-27-2014 |
20140346378 | MICROFLUIDIC VALVE MODULE AND SYSTEM FOR IMPLEMENTATION - An improved microfluidic system with an improved microfluidic valve module is disclosed. The microfluidic system includes a microfluidic chip and one or more valve modules. The microfluidic chip has microfluidic channels and one or more cavities formed in the chip, each of the one or more cavities designed to receive one of the one or more valve modules. Each of the one or more valve modules includes a first layer, a control layer and one or more second layers. The first layer includes a deformable material. The control layer has a microfluidic control chamber formed in a portion of it. The control layer is also located adjoining the first layer and the deformable material of the first layer forms a deformable surface of the control chamber. The one or more second layers include an input microfluidic channel and an output microfluidic channel. The input microfluidic channel and the output microfluidic channel are fluidically coupled to the microfluidic control chamber, and fluid flow through the input microfluidic channel, the microfluidic control chamber and the output microfluidic channel is controlled in response to a force deforming the deformable material of the first layer at least a predetermined amount. | 11-27-2014 |
20140335510 | NANOPARTICLE SENSOR FOR NUCLEIC ACID-PROTEIN INTERACTION - The present invention provides a sensor for sensing nucleic acid-protein interactions, comprising a noble metal nanoparticle (NP), a double stranded nucleic acid molecule capable of binding with a protein in an aqueous solution and a fluorescent conjugated polymer (CP). The present invention also provides a method for sensing nucleic acid-protein interactions with the sensor as defined above. | 11-13-2014 |
20140321002 | MAGNETIC DISK DRIVE DEVICE, MAGNETIC DISK ASSEMBLY AND METHODS OF FORMING THE SAME - A magnetic disk drive device for rotary driving a magnetic disk may be provided. The magnetic disk drive device may include a drive motor for rotary driving the magnetic disk. The drive motor may include a motor hub which has motor hub support portion with a screw-type motor hub engaging portion, and a motor hub support surface for supporting the magnetic disk. The magnetic disk drive device may also include a clamp disk including a clamp disk support portion with a screw-type clamp disk engaging portion complementary to the motor hub engaging portion, and a clamp disk support surface for supporting the magnetic disk. | 10-30-2014 |
20140320820 | METHOD AND DEVICE FOR MONITORING RETINOPATHY - There is provided a method of monitoring retinopathy in a subject. The method involves measuring autofluorescence of a retina in response to high intensity blue light and infra-red reflectance of the anterior region of an eye in response to high intensity infra-red light of the subject over a total time period to obtain an autofluorescence intensity profile and an infra-red reflectance intensity profile. The autofluorescence intensity profile and infra-red reflectance intensity profile are processed to obtain a pupillary light reflex measurement that is used to assess the retinopathy status of the retina. | 10-30-2014 |
20140319638 | AVALANCHE PHOTODIODE - According to one aspect, there is provided an avalanche photodiode comprising a first semiconductor layer that absorbs photons of a first wavelength range and having a first energy bandgap; a second semiconductor layer that absorbs photons of a second wavelength range and having a second energy bandgap, the second energy bandgap being different from the first energy bandgap; and a control layer between the first semiconductor layer and the second semiconductor layer, the control layer having a third energy bandgap engineered to suppress carriers created from dark current. | 10-30-2014 |
20140319317 | PHOTO-SENSOR - According to one aspect of the invention, there is provided a photo-sensor comprising: an optically transparent substrate; an electrode pair; and a photoactive film with electrical polarization located between the optically transparent substrate and the electrode pair, wherein the optically transparent substrate is configured to transmit incident radiation received by the optically transparent substrate to the photoactive film and wherein the electrode pair is configured to receive charge carriers generated by the photoactive film in response to the transmitted incident radiation. | 10-30-2014 |
20140315973 | PARP-1 INHIBITORS - We describe a nucleic acid comprising the sequence RNNWCAAA, in which R is independently G or A, N is independently T, C, G or A and W is independently T or A, suitable for the treatment or prevention of hepatitis B or cancer. N at position 3 may be C, A or T, preferably A or T, more preferably T; N at position 2 may be C; W at position 4 may be T; and R at position 1 may be A. The nucleic acid may have the sequence ACATCAAA or ACTTCAAA. | 10-23-2014 |
20140315300 | Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 10-23-2014 |
20140302884 | METHOD OF TRANSMITTING DATA BETWEEN A PLURALITY OF BASE STATIONS AND A PLURALITY OF MOBILE STATIONS - A method of transmitting data between a plurality of base stations and a plurality of mobile stations is provided. The method includes ranking data links between the plurality of base stations and the plurality of mobile stations according to a quality criterion, and selecting a subset of data links for transmitting the data between the plurality of base stations and the plurality of mobile stations such that a predetermined requirement is satisfied. Selecting the subset of data links may include iteratively assigning a predetermined value to power of the data link having the lowest ranking and determining if the predetermined requirement is satisfied, until the predetermined requirement is no longer satisfied. The remaining data links may then be selected for transmitting the data between the plurality of base stations and the plurality of mobile stations. | 10-09-2014 |
20140301968 | ANTIMICROBIAL CATIONIC POLYCARBONATES - Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi. | 10-09-2014 |
20140301967 | ANTIMICROBIAL CATIONIC POLYCARBONATES - Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi. | 10-09-2014 |
20140286937 | ANTIBODIES BINDING TO AN INTRACELLULAR PRL-1 OR PRL-3 POLYPEPTIDE - We provide an antibody capable of binding to an intracellular PRL-I or PRL-3 polypeptide, in which the antibody is capable of binding to an epitope bound by antibody 269, antibody 223 or antibody 318. Such anti-PRL antibodies may be capable of binding to intracellular PRL-I or PRL-3. They may be suitable for use as therapies against cancer or metastasis thereof, or in clinical diagnosis to identify PRL-3 or PRL-I positive patients. | 09-25-2014 |
20140272372 | LAYERED SILICATE/POLYMER COMPOSITE AND A METHOD OF FORMING THE SAME - The present invention relates to a method for forming a layered silicate/polymer composite, the composite comprising individual exfoliated silicate layers separated in a continuous polymer matrix, wherein the polymer is a hydrophobic polymer, the method comprising: exfoliating sheet silicate in water to form a silicate suspension; replacing the water in the silicate suspension by an organic solvent to form a silicate/organic solvent suspension; contacting the silicate/organic solvent suspension with a solution of a hydrophobic polymer precursor in an organic solvent to form a silicate/polymer precursor suspension; coating the silicate/polymer precursor suspension on a substrate; removing the organic solvents; curing the hydrophobic polymer precursor of the coating of the silicate/polymer precursor; and annealing the cured coating to form the layered silicate/polymer composite on the substrate. | 09-18-2014 |
20140256812 | NOVEL ANTIMICROBIAL COMPOUNDS AND USES THEREOF - The present invention relates to novel antimicrobial compounds, methods of their production as well as uses thereof. | 09-11-2014 |
20140256625 | ANTI-AMYLOIDOGENIC, ALPHA-HELIX BREAKING ULTRA-SMALL PEPTIDE THERAPEUTICS - The invention provides ultra-small peptide inhibitors that are capable of preventing amyloid formation/amyloidosis. | 09-11-2014 |
20140252342 | ENCAPSULATION BARRIER STACK - Disclosed is an encapsulation barrier stack, capable of encapsulating a moisture and/or oxygen sensitive article and comprising a multilayer film, wherein the multilayer film comprises: one or more barrier layer(s) having low moisture and/or oxygen permeability, and one or more sealing layer(s) arranged to be in contact with a surface of the at least one barrier layer, thereby covering defects present in the barrier layer, wherein the one or more sealing layer(s) comprise(s) a plurality of encapsulated nano-particles, the nanoparticles being reactive in that they are capable of interacting with moisture and/or oxygen to retard the permeation of moisture and/or oxygen through the defects present in the barrier layer. The encapsulation of the particles can be obtained by polymerising a polymerisable compound (a monomeric or a polymeric compound with polymerisible groups or) cross-linking a cross-linkable compound on the surface of the reactive nanoparticles. | 09-11-2014 |
20140247770 | CYCLIC PREFIX SCHEMES - Methods and systems are proposed for transmitting data from a source ( | 09-04-2014 |
20140244228 | CODON OPTIMIZATION OF A SYNTHETIC GENE(S) FOR PROTEIN EXPRESSION - The present disclosure is related to a method of optimization of a nucleotide coding sequence coding for an amino acid sequence, wherein the nucleotide coding sequence is optimized for expression in a host cell. The present disclosure also relates to system for optimizing a nucleotide coding sequence coding for an amino acid sequence, wherein the nucleotide coding sequence is optimized for expression in a host cell. | 08-28-2014 |
20140234873 | APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME - A device for processing a sample in a liquid droplet containing a hydrophilic liquid is described. The device includes: a circumferential wall and a base including an immobilisation member. The circumferential wall and the base define a reservoir adapted to accommodate a hydrophobic medium immiscible with the liquid droplet. The medium is of a lower surface energy than a liquid of the liquid droplet. The immobilisation member includes a surface with a plurality of hydrophilic immobilisation areas and a hydrophobic area. The plurality of hydrophilic immobilisation areas is: (a) of a higher surface energy than the medium, (b) of a higher surface energy than the hydrophobic area, and (c) of a sufficient surface energy and a sufficient width to allow, in the medium, immobilisation of liquid droplets on the hydrophilic immobilisation areas via interfacial interactions. Methods of using and rinsing the device are also described. | 08-21-2014 |
20140231784 | POLYMERIC SEMICONDUCTORS, DEVICES, AND RELATED METHODS - A polymer comprises a polymeric chain represented by formula (I) or (II). In formula (I) a, b, d, and n are integers, a from 0 to 3, b from 1 to 5, c from 1 to 3, d from 1 to 5, and n from 2 to 5000; R | 08-21-2014 |
20140220093 | CATIONIC POLYMERS FOR ANTIMICROBIAL APPLICATIONS AND DELIVERY OF BIOACTIVE MATERIALS - A cationic star polymer is disclosed of the general formula (1): | 08-07-2014 |
20140199381 | CORE-SHELL MICROSPHERES - The specification describes a substance comprising a plurality of microparticles. The microparticles comprise a core comprising a first polymer and a shell surrounding said core and comprising the first polymer and a second polymer, wherein the second polymer is less rapidly degradable than the first polymer. A process for making the microparticles and uses of the microparticles are also described. | 07-17-2014 |
20140193903 | Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 07-10-2014 |
20140193849 | GLUCOSE-PEG CONJUGATES FOR REDUCING GLUCOSE TRANSPORT INTO A CELL - There is provided a glucose-PEG conjugate comprising a PEG moiety conjugated to a linear glucose moiety at the C1 position of the glucose moiety. The glucose-PEG conjugate may be used to reduce glucose transport into a cell and may be used to treat a proliferative disorder. | 07-10-2014 |
20140192178 | METHOD AND SYSTEM FOR TRACKING MOTION OF MICROSCOPIC OBJECTS WITHIN A THREE-DIMENSIONAL VOLUME - Phase contrast microscopy images are collected of a liquid sample containing one or more microscopic objects. The images are analyzed to track the motion of the microscopic objects within the liquid sample. Using the updated locations of the tracking objects, a controller can generate control signals for controlling the microscopy parameters, to ensure that the portion of the liquid sample which is imaged includes the tracking objects. The tracking objects may be cells or cell-spheres. Thus, the system can, for example, track cells and cell-spheres, to observe their growth, during a long time-lapse experiment. | 07-10-2014 |
20140183448 | VERTICAL LIGHT EMITTING DIODE WITH PHOTONIC NANOSTRUCTURES AND METHOD OF FABRICATION THEREOF - There is provided a method of fabricating a vertical light emitting diode which includes forming a light emitting diode structure. Forming the light emitting diode structure includes: forming a first material layer of a first conductivity type, forming a second material layer of a second conductivity type, forming a light emitting layer between the first material layer and the second material layer, and forming a plurality of generally ordered photonic nanostructures at a surface of the first material layer through which light generated from the light emitting layer is emitted for enhancing light extraction efficiency of the vertical light emitting diode. In particular, forming a plurality of generally ordered photonic nanostructures includes forming a self-assembled template including generally ordered nanoparticles on the surface of the first material layer to function as a mask for forming the photonic nanostructures at said surface of the first material layer. There is also provided a vertical light emitting diode with the self-assembly derived ordered nanoparticles. | 07-03-2014 |
20140179040 | MULTILAYER FILM FOR ENCAPSULATING OXYGEN AND/OR MOISTURE SENSITIVE ELECTRONIC DEVICES - The present invention relates to a multilayer barrier film capable of encapsulating a moisture and/or oxygen sensitive electronic or optoelectronic device, the barrier film including at least one nanostructured layer including reactive nanoparticles capable of interacting with moisture and/or oxygen, the reactive nanoparticles being distributed within a polymeric binder, and at least one ultraviolet light neutralizing layer comprising a material capable of absorbing ultraviolet light, thereby limiting the transmission of ultraviolet light through the barrier film. | 06-26-2014 |
20140170224 | GELATIN-BASED MICROGELS - A gelatin-based microgel was prepared by a simple method starting from gelatin and alginate. The microgel was composed of a soft gelatin-based core coated by a permeable membrane. Gelatin-based core was moderately crosslinked by a novel crosslinker 4-arm PEG succinimidyl glutarate (pentaerytheritol core) (sPEG-4A-GS(10 k)). | 06-19-2014 |
20140167995 | ANALOG-TO-DIGITAL CONVERTER - According to embodiments of the present invention, an analog-to-digital converter is provided. The analog-to-digital converter includes an input configured to receive an input signal, a feed-forward path connected to the input configured to feed forward the input signal, a processing path including a loop filter, wherein the loop filter includes at least one local feedback path configured to feed back an output signal of the loop filter to an input of the loop filter, a first combiner configured to combine the input signal fed forward by the feed-forward path with an output of the processing path, a quantizer configured to generate an output signal of the converter, a feed-back path configured to feed back the output signal, and a second combiner wherein the processing path is connected to the second combiner and the second combiner is configured to combine the input signal with the fed back output signal of the converter and supply the result of the combination to the processing path. | 06-19-2014 |
20140167200 | PHOTODETECTOR AND METHOD FOR FORMING THE SAME - According to embodiments of the present invention, a photodetector is provided. The photodetector includes a substrate having a first side and a second side opposite to the first side, the substrate being adapted to receive light incident on the photodetector on the first side of the substrate, a plurality of cells formed in the substrate, and at least one trench defined by a first sidewall and a second sidewall, wherein a spacing between the first sidewall and the second sidewall increases in a direction from the first side of the substrate towards the second side, wherein a respective trench of the at least one trench is arranged in between adjacent cells of the plurality of cells. According to further embodiments of the present invention, a method for forming a photodetector is also provided. | 06-19-2014 |
20140163641 | MUSCLE STIMULATION SYSTEM - According to one aspect of the invention, there is provided a muscle stimulation system for effecting appendage movement, the muscle stimulation system comprising: first transceiver circuitry; at least one first implantable stimulation device for implantation adjacent to one or more first muscles responsible for the appendage movement, the first implantable stimulation device configured to be wirelessly activated by the first transceiver circuitry; second transceiver circuitry; at least one second implantable stimulation device for implantation adjacent to one or more second muscles responsible for the appendage movement, the second implantable stimulation device configured to be wirelessly activated by the second transceiver circuitry; and a base station configured to wirelessly communicate with both the first transceiver circuitry and the second transceiver circuitry to receive and transmit signals that causes coordinated activation of the first implantable stimulation device and/or the second implantable stimulation device to coordinate stimulation of the first muscles and/or the second muscles that are responsible for the appendage movement. | 06-12-2014 |
20140162254 | BREAST TUMOUR GRADING - We describe a method of assigning a grade to a breast tumour, which grade is indicative of the aggressiveness of the tumour, the method comprising detecting the expression of a gene selected from the genes set out in Table D1 (SWS Classifier 0). | 06-12-2014 |
20140153600 | Optical Light Source - An optical light source is provided. The optical light source includes a waveguide including two reflectors arranged spaced apart from each other to define an optical cavity therebetween, an optical gain medium, and a coupling structure arranged to couple light between the optical cavity and the optical gain medium. | 06-05-2014 |
20140149773 | LATCH CIRCUIT AND DATA PROCESSING SYSTEM - A latch circuit is described comprising a switchable resistive element and a switching circuit configured to set the switchable resistive element to a first resistive state in response to receiving a set signal and to set the switchable resistive element to a second resistive state in response to receiving a reset signal. | 05-29-2014 |
20140148886 | NERVE STUMP INTERFACE AND AXONAL REGENERATION SYSTEM FOR GENERATING AN ELECTRIC FIELD FOR PROMOTING AND GUIDING AXONAL REGENERATION - The present invention provides a nerve stump interface for generating an electric field for promoting and guiding axonal regeneration and an electric field assisted axonal regeneration system. The nerve stump interface comprises a sieve having a plurality of holes. A strip is coupled to the sieve. A first electrode is provided at one of the plurality of holes and a second electrode is provided on the strip. The strip is arranged to space the second electrode from the first electrode. The first electrode and the second electrode are for generating the electric field. At least one securing element is provided on a side of the strip to allow that side of the strip to affix against an opposite side of the strip. The present invention also provides a method for assembling the electric field assisted axonal regeneration system. | 05-29-2014 |
20140148185 | Base Station and Method of Operating the Same - The present invention is directed to a base station including a transceiver configured to communicate with another base station using a radio resource, wherein the radio resource is allocated to the base station to serve communication devices located in a radio cell operated by the base station. A method of operating a base station is also disclosed. | 05-29-2014 |
20140147955 | METHOD OF ENCAPSULATING A MICRO-ELECTROMECHANICAL (MEMS) DEVICE - A method for encapsulating a micro-electromechanical (MEMS) device, the method comprising: providing a sacrificial layer arrangement over the MEMS device; providing a first encapsulation layer over the sacrificial layer arrangement, the first encapsulation layer defining at least one aperture; providing a second encapsulation layer over the at least one aperture, the second encapsulation layer being provided to allow removal of the sacrificial layer arrangement around the second encapsulation layer; and removing the sacrificial layer arrangement through the at least one aperture to allow the second encapsulation layer to cover the at least one aperture thereby encapsulating the MEMS device. | 05-29-2014 |
20140142304 | PROCESS FOR PRODUCING AN AMINOPROPYNE OR ENAMINONE - There is provided a process for producing an aminopropyne or an enaminone comprising the step of reacting a metal acetylide, an amine and a carbonyl-containing compound in the presence of a transition metal catalyst. There is also provided a process for producing an aminopropyne comprising the step of reacting a metal acetylide, an amine and a halide-containing compound in the presence of a transition metal catalyst at a reaction temperature of 50° C. to 150° C. There are also provided processes to further synthesize the aminopropyne produced to obtain a butyneamine, another aminopropyne or a triazol. | 05-22-2014 |
20140142027 | MULTIMERIC FORMS OF ANTIMICROBIAL PEPTIDES - The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3. The method includes a composition or combination comprising the multimeric antimicrobial peptides and at least one active pharmaceutical ingredient. | 05-22-2014 |
20140139953 | DESIGN AND METHOD OF OPERATION OF MICRO-MILLIACTUATORS AND MICRO-MICROACTUATORS - A micro-milliactuator, a micro-microactuator, an actuator arm assembly, a hard disk drive and a method for operation of the hard disk are provided. In accordance with one aspect, the actuator arm assembly includes an arm, a slider for reading and writing information to disk media in response to read/write signals, and an actuator selected from the group comprising a micro-milliactuator and a micro-microactuator. The actuator has the slider mounted thereon and supports it above the disk media. The actuator includes one or more piezoelectric actuators for horizontally shifting the slider in response to actuator control signals. The actuator further includes one or more sensors physically coupled thereto for vibration sensing, compensation and suppression, the one or more sensors generating sensor signals in response to sensed vibrations during operation, wherein the actuator control signals are generated at least partially in response to the sensor signals. | 05-22-2014 |
20140138789 | P-I-N PHOTODIODE - According to one aspect of the invention, there is provided a pin photodetector comprising a dopant diffusion barrier layer disposed within an active light absorbing region of the pin photodetector. | 05-22-2014 |
20140134609 | ENZYMATIC METAL NANOPARTICLE SENSOR FOR DETECTING DNA BINDERS - The present invention provides a colorimetric method for detecting a polynucleotide strand binding molecule using one type of metal particles modified with a single type of interacting molecules. The interacting molecule is capable of specifically binding to nucleic and of protecting the metal particle from aggregation. Furthermore, the metal particles are capable of aggregation upon salt aggregation and/or cleavage of the interacting molecule, and colorimetric change changes upon aggregation. | 05-15-2014 |
20140134194 | HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF - There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC. | 05-15-2014 |
20140127842 | METHOD FOR FORMING AN OPTICAL MODULATOR - According to embodiments of the present invention, a method for forming an optical modulator is provided. The method includes providing a substrate, implanting dopants of a first conductivity type into the substrate to form a first doped region, implanting dopants of a second conductivity type into the substrate to form a second doped region, wherein a portion of the second doped region is formed over and overlaps with a portion of the first doped region to form a junction between the respective portions of the first doped region and the second doped region, and wherein a remaining portion of the second doped region is located outside of the junction, and forming a ridge waveguide, wherein the ridge waveguide overlaps with at least a part of the junction. | 05-08-2014 |
20140125325 | SENSOR AND METHOD OF CONTROLLING THE SAME - According to embodiments of the present invention, a sensor is provided. The sensor includes a substrate, a beam suspended from the substrate, and a plurality of conductive lines arranged on the beam, wherein the beam is adapted to be displaced in response to a current flowing through the plurality of conductive lines, and a magnetic field interacting with the beam, and wherein the sensor is configured to determine a property of the magnetic field based on the displacement of the beam. According to further embodiments of the present invention, a method of controlling a sensor is also provided. | 05-08-2014 |
20140123737 | Apparatus for Detecting Particles in a Fluid and a Method of Fabricating the Same - An apparatus for detecting particles in a fluid is provided including a substrate, a plurality of channel through holes extending through the substrate, wherein the channel through holes are configured to carry the fluid, a plurality of circuits monolithically integrated with the substrate, wherein each circuit of the plurality of circuitries is arranged adjacent a respectively assigned channel through hole, each circuit including a detection electrode and an control circuit coupled to the detection electrode and configured to control access to the detection electrode, wherein each detection electrode is positioned relative to the respectively assigned channel through hole such at least one electrical property of the fluid flowing through the channel through hole can be detected. | 05-08-2014 |
20140121129 | Alkylamino BODIPY Dyes As Selective Fluorescent Probes For Proteins And Mouse Embryonic Stem Cells - The present invention discloses a series of alkylamino BODIPY dyes, methods for preparing a library of alkyl-amino BODIPY dyes via solid-phase synthesis, and the use of the alkyl-amino BODIPY dyes as fluorescent sensors for protein detection, cell imaging and cytometry applications, and staining of certain cell line. | 05-01-2014 |
20140120314 | SUPER-HYDROPHOBIC HIERARCHICAL STRUCTURES, METHOD OF FORMING THEM AND MEDICAL DEVICES INCORPORATING THEM - Synthetic polymer substrates comprising a hierarchical surface structure of multiple domes and multiple pillars on said domes, wherein said substrate is a synthetic polymer film, said domes have diameters in the range from about 5 μm to about 400 μm, heights in the range from about 2.5 μm and about 500 μm, and said pillars have diameters in the range from about 20 nm to about 5 μm and aspect ratios of from about 2 to about 50, and methods of making and using them. | 05-01-2014 |
20140119687 | FIBER BRAGG GRATING (FBG) SENSOR - A fiber Bragg grating (FBG) sensor structure, a method of fabricating a FBG sensor structure, and a method of employing a FBG sensor structure comprising an optical fiber portion having at least one FBG formed therein. The FBG sensor structure comprises an optical fiber portion having at least one FBG formed therein; and a sleeve structure capable of transferring vibrations and/or strain along a length thereof; wherein the optical fiber portion is coupled to the sleeve structure such that the central wavelength of the FBG, is variable under the transferred vibrations and/or strain. | 05-01-2014 |
20140115238 | STORAGE CONTROLLERS AND STORAGE CONTROL METHODS - According to various embodiments, a storage controller configured to control storage of data in a pre-determined area of a storage medium may be provided. The storage controller may include a memory configured to store a write pointer, a reclaim pointer, and a wrapped around pointer. The write pointer may indicate a location of the storage medium to write incoming data. The reclaim pointer may indicate a location of the storage medium to perform a space reclamation. The wrapped around pointer may indicate a location of the storage medium where writing is to continue if writing of data reaches an end of the pre-determined area. | 04-24-2014 |
20140112066 | Circuit Arrangement and Method of Forming the Same - In various embodiments, a circuit arrangement may be provided including a data cell. The circuit arrangement may further include a first transistor and a second transistor. The first controlled electrode of the first transistor and the first controlled electrode of the second transistor may be coupled to the first electrode of the data cell. The second controlled electrode of the first transistor may be configured to electrically connect to a first reference voltage such that the first electrode of the data cell is electrically connected to the first reference voltage when the first transistor is activated. The second controlled electrode of the second transistor may be configured to electrically connect to a second reference voltage, such that the first electrode of the data cell is electrically connected to the second reference voltage when the second transistor is activated. | 04-24-2014 |
20140110804 | MAGNETORESISTIVE DEVICE AND METHOD FOR FORMING THE SAME - According to embodiments of the present invention, a magnetoresistive device is provided. The magnetoresistive device includes a free magnetic layer structure having a variable magnetization orientation, and a synthetic antiferromagnetic layer structure including at least three ferromagnetic layers arranged one over the other and antiferromagnetically coupled, each ferromagnetic layer having a fixed magnetization orientation, wherein the free magnetic layer structure and the synthetic antiferromagnetic layer structure are arranged one over the other. According to further embodiments of the present invention, a method for forming a magnetoresistive device is also provided. | 04-24-2014 |
20140107176 | METHOD OF MODULATING A PROSTATE CANCER CELL - There is provided a method of modulating a prostate cancer cell, the method comprising administering to the prostate cancer cell an agent that augments vinculin expression levels in the cell. | 04-17-2014 |
20140105007 | Method and Device for Mobile Data Offload - Embodiments provide a mobile data offload method for associating a mobile client device with a wireless access point. The method may include transmitting a first authentication request from the mobile client device to the wireless access point via a first network being a Cellular Wide Area radio communication network; transmitting a second authentication request from the mobile client device to the wireless access point via a second network being a Short Range radio communication network or a Metropolitan Area System radio communication network; transmitting an authentication response from the wireless access point to the mobile client device via the second network upon receiving at least one of the first authentication request and the second authentication request at the wireless access point, and associating the mobile client device with the wireless access point upon receiving the authentication response at the mobile client device. | 04-17-2014 |
20140104010 | Method and Apparatus for a Duty-Cycled Harmonic Injection Locked Oscillator - A method and an apparatus for a duty-cycled injection locked oscillator is provided for frequency shift keyed (FSK) signal transmissions. The oscillator includes a resonance LC tank and a first switching device. The first switching device is coupled to the resonance LC tank and injects an initial current pulse with a predetermined pulse magnitude into the resonance LC tank. The initial current pulse also fixes an initial phase of the duty-cycled injection locked free-running oscillator in response to the predetermined magnitude of the initial current pulse to enable fast settling of injection locking and high data rate operation of the duty-cycled injection locked oscillator. The oscillator also includes a second switching device, such as a differential pair of switching devices. The second switching device is coupled to the LC resonance tank for injecting a gated periodic reference signal having a duty cycle modified to reduce power of the reference signal by approximately seventy-five per cent. | 04-17-2014 |
20140092718 | METHOD OF WRITING TO AN OPTICAL DATA STORAGE MEDIUM, METHOD OF READING FROM AN OPTICAL DATA STORAGE MEDIUM, AND OPTICAL DATA STORAGE MEDIUM - According to embodiments of the present invention, a method of writing to an optical data storage medium is provided. The method includes receiving a plurality of data elements, each data element having one of a plurality of values, wherein each value of the plurality of values is associated with a wavelength, and forming, for each data element, a nanostructure arrangement on the optical data storage medium, the nanostructure arrangement configured to reflect light of the wavelength associated with the value of the data element in response to a light irradiated on the optical data storage medium. According to further embodiments of the present invention, a method of reading from an optical data storage medium and an optical data storage medium are also provided. | 04-03-2014 |
20140087192 | CONDUCTING POLYMER/GRAPHENE-BASED MATERIAL COMPOSITES, AND METHODS FOR PREPARING THE COMPOSITES - A composite comprising a conducting polymer and a graphene-based material is provided. The composite includes a graphene-based material doped with nitrogen or having a nitrogen-containing species grafted thereon, and a conducting polymer arranged on the graphene-based material. Methods of preparing the composite, and electrodes formed from the composite are also provided. | 03-27-2014 |
20140086925 | FGFR1 ANTIBODIES AND TREATMENT OF CANCER - The use of an FGFR1 antibody in the treatment of cancer is disclosed, wherein the FGFR1 antibody binds FGFR1 at an epitope that is positioned in the FGFR1 primary amino acid sequence no more than 50 contiguous amino acids away from the C- or N-terminal of the FGFR1 heparin binding domain. | 03-27-2014 |
20140080215 | BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS - A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): | 03-20-2014 |
20140078505 | OPTICAL DEVICE, METHOD OF FORMING AN OPTICAL DEVICE, AND METHOD FOR DETERMINING A PARAMETER OF A FLUID - According to embodiments of the present invention, an optical device is provided. The optical device includes an optical fiber comprising a core for propagation of light and a cladding surrounding the core, and at least one microchannel defined in the optical fiber extending at least partially through the cladding, wherein the at least one microchannel has a concave-shaped surface arranged to interact with an optical field of the light. According to further embodiments of the present invention, a method of forming an optical device and a method for determining a parameter of a fluid are also provided. | 03-20-2014 |
20140073048 | LOW MOLECULAR WEIGHT BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS - A branched polyamine comprises about 8 to about 12 backbone tertiary amine groups, about 18 to about 24 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): | 03-13-2014 |
20140072607 | POLYCARBONATES BEARING PENDANT PRIMARY AMINES FOR MEDICAL APPLICATIONS - An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2): | 03-13-2014 |
20140071801 | METHOD AND SYSTEM FOR HIGH BANDWIDTH AND LOW POWER BODY CHANNEL COMMUNICATION - A system and method for body channel communication is provided. The system includes a transceiver which encodes multiple bits per symbol when operating in a high data rate mode by selecting a first Walsh code in response to a first set of multiple bits of data and selecting a second Walsh code in response to a second set of multiple bits of data, both Walsh codes selected from a multiple-bit Walsh code sequence. The transceiver also generates a multi-level transmission signal having a predetermined symbol frequency by stacking the first Walsh code onto the second Walsh code, and transmits the multi-level signal having the first predetermined symbol frequency through the body channel. The transceiver also has additional modes of operation which include a normal mode and a low power mode, the low power mode decoding the multiple bits from the signal in response to harmonic energy from a harmonic frequency generated by the multiple-bit Walsh code sequence. Also, the transceiver modulates an M-Sequence code with the multi-bit Walsh code sequence up to a desired frequency band associated with the predetermined frequency in order to improve auto-correlation after passing through the body channel. | 03-13-2014 |
20140071722 | ENERGY HARVESTING APPARATUS AND A METHOD FOR OPERATING AN ENERGY HARVESTING APPARATUS - In various embodiments of the present disclosure, there is provided an energy harvesting apparatus, including: an energy harvester for generating electric power from an ambient source; a power conditioning circuit coupled to the output of the energy harvester; including: a boost converter module; a buck-boost converter module; and a power modification control module; wherein the power modification control module is configured to initialize the energy harvesting apparatus from inactivity to a normal energy harvesting state by operating the boost converter module, and operating the buck-boost converter when an output voltage of the power conditioning circuit rises to a predetermined value. A corresponding method of operating an energy harvesting apparatus is provided. | 03-13-2014 |
20140070033 | METHOD OF BREAKING DOWN BIOLOGICAL MATERIAL - In various embodiments, a method of breaking down biological material is provided. The method may include providing a sample comprising the biological material in a liquid. The method may further include providing a gas such that the gas forms an interface with the liquid. The method may also include breaking down the biological material by applying acoustic waves in a plurality of sequential bursts to the interface. | 03-13-2014 |
20140057637 | Communication Terminal and Method for Performing Communication - A method for enabling a forwarding to network operation in a cellular mobile communication system is described, the cellular mobile communication system comprising a plurality of mobile stations and at least one base station, the method comprising: reporting forwarding capability of a first mobile station of the plurality of mobile stations with the at least one base station; discovering neighboring mobile stations to the first mobile station; selecting a second mobile station from the neighboring mobile stations and establishing a forwarding link between the first mobile station and the second mobile station; allocating radio resources for a link between the first mobile station and the second mobile station; and synchronizing the link between the first mobile station and the second mobile station to establish the forwarding network. | 02-27-2014 |
20140056248 | Communication Devices and Methods for Performing Communication - In a first implementation, a method for performing direct mobile-to-mobile communication in a cellular mobile communication system, the cellular mobile communication system having at least two mobile stations and a communication network for providing a communication connection between the at least two mobile stations via at least one base station of the communication network is provided, method for performing direct mobile-to-mobile communication in a cellular mobile communication system includes associating a first mobile station and a second mobile station with the at least one base station, performing neighbor discovery between the first mobile station and the second mobile station for reporting to the at least one base station, detecting the feasibility of direct communication between the first mobile station and the second mobile station, establishing a direct communication link between the at least two mobile stations, allocating identification for communication and flow and resources for a flow between the first mobile station and the second mobile station, synchronizing the flow between the first mobile station and the second mobile station, and sending automatic repeat requests (ARQ) messages. | 02-27-2014 |
20140056124 | Communication Devices and Methods for Performing Communication - A infrastructure station in a cellular mobile communication system, the infrastructure station includes a infrastructure station core configured to provide infrastructure station functionality to a plurality of dependent stations, a topographer configured to discover a network topology and designate a failover topology from the network topology for use in the event that the infrastructure station fails thereby no longer being capable of providing infrastructure station functionality to the plurality of dependent stations, the failover topology comprising failover stations, and a synchronizer configured to periodically provide timing estimates of dependent stations to the failover stations such that network reentry after infrastructure station failure is shorter than normal network entry. | 02-27-2014 |
20140056096 | MICROFLUIDIC AGITATOR DEVICES AND METHODS FOR AGITATION OF A FLUID - According to various embodiments, a microfluidic agitator device may be provided. The microfluidic agitator device may include: an air inlet; an air outlet; an elastic diaphragm provided between the air inlet and the air outlet and configured to oscillate if an airflow from the air inlet to the air outlet is provided; and a chamber coupled to the elastic diaphragm. | 02-27-2014 |
20140054742 | Semiconductor Structure - Various embodiments provide a semiconductor structure. The semiconductor structure may include a semiconductor substrate; a via extending through the semiconductor substrate; and a capacitive structure surrounding at least a portion of the via. The capacitive structure may include a metal layer formed on the semiconductor substrate. | 02-27-2014 |
20140052985 | METHODS FOR PROVIDING REQUESTED DATA FROM A STORAGE DEVICE TO A DATA CONSUMER AND STORAGE DEVICES - According to various embodiments, a method for providing requested data from a storage device to a data consumer may be provided. The method may include: determining a helper key for the data consumer; determining encrypted data corresponding to the requested data from a memory of the storage device; determining pre-processed data based on the encrypted data and the helper key, wherein the pre-processed data is encrypted and configured to be decrypted using a private key of the data consumer; and transmitting the pre-processed data to the data consumer. | 02-20-2014 |
20140051109 | NOVEL COMPOUNDS WITH PHOTOLUMINESCENCE PROPERTIES AND APPLICATIONS THEREOF - The present invention relates to compounds of a general formula (I) having photoluminescence properties. The present invention also relates to applications, such as protein imaging tools, involving such compounds. | 02-20-2014 |
20140050754 | IMMUNOGENIC CHIKUNGUNYA VIRUS PEPTIDES - The present invention relates to immunogenic peptides of Chikungunya Virus and methods for vaccinating a subject using these peptides. Also disclosed are nucleic acids encoding these peptides and methods for their production. | 02-20-2014 |
20140046005 | HYBRID POLYMERS - Described herein are polymers comprising a polyester and at least one polyhedral oligomeric silsesquioxane, wherein the polyester is capable of forming a stereocomplex with a polymer comprising a complimentary polyester and composites thereof. | 02-13-2014 |
20140042324 | DETECTOR AND METHOD OF CONTROLLING THE SAME - According to embodiments of the present invention, a detector is provided. The detector includes an electromagnetic absorber, an electromagnetic reflector arranged spaced apart from the electromagnetic absorber, wherein the electromagnetic absorber is configured to absorb an electromagnetic radiation, the electromagnetic radiation having a wavelength defined based on a distance between the electromagnetic absorber and the electromagnetic reflector, and an actuating element configured to move the electromagnetic absorber from an equilibrium position bi-directionally relative to the electromagnetic reflector to change the distance, and wherein the detector is configured to determine a change in a property associated with the electromagnetic absorber in response to the electromagnetic radiation. According to further embodiments of the present invention, a method of controlling the detector is also provided. | 02-13-2014 |
20140036815 | METHOD FOR DETERMINING PRECODING MATRIXES FOR COMMUNICATION AND A SYSTEM THEREFROM - In various embodiments of the present disclosure, there is provided a method for determining precoding matrixes for a communication of a first base station and a second base station with a first mobile station and a second mobile station. Precoding matrixes for a plurality of signal channels between the base stations and the mobile stations are determined based on a signal to noise ratio (SNR) consideration. Accordingly, the method can include determining a first set of precoding matrixes based on a predetermined consideration of SNR between the first base station and the second base station and the first mobile station and the second mobile station and generating a second set of precoding matrixes based on the first set of precoding matrixes. A corresponding system for carrying out a determination of precoding matrixes is provided. | 02-06-2014 |
20140034815 | SELF-POWERED PHOTODETECTOR AND METHOD OF FABRICATION THEREOF - A self-powered photodetector is provided including: a photovoltaic sensor element for generating an electrical charge under exposure to electromagnetic radiation; a charge storage section for accumulating the electrical charge generated by the photovoltaic sensor element; an electrical load configured to be powered by the accumulated electrical charge from the charge storage section and outputs a signal in response thereto, the signal being analyzable to determine a measurement of the electromagnetic radiation; and a switch for controlling a flow of the accumulated electrical charge from the charge storage section to the electrical load for powering the electrical load. There is also provided a wireless receiver for analyzing a signal from the self-powered photodetector to provide a measurement of the electromagnetic radiation, a photodetector system including the self-powered photodetector and the wireless receiver, and a method of fabricating the self-powered photodetector. | 02-06-2014 |
20140031256 | METHODS OF DETECTING THERAPEUTIC EXOSOMES - We describe a method of detecting a therapeutic exosome, the method comprising detecting an activity of an exosome. The activity may be selected from the group consisting of: (a) immunodulatory activity; (b) complement inhibition activity; (c) proteasome activity; (d) glycolytic enzyme activity; (e) anti-oxidative activity; (f) extracellular matrix (ECM) modifying activity; (g) NT5E (CD73) ecto-5′-ectonucleotidase activity; (h) ion homeostasis activity; and (i) chaperone activity. If the exosome is detected as having one or more such activities, the exosome is likely to comprise a therapeutic exosome having therapeutic activity. | 01-30-2014 |
20140030551 | Recording Medium and Method of Forming the Same - In various embodiments, a recording medium may be provided. The recording medium may include a servo layer. The recording medium may further include a data recording layer. The recording medium may additionally include a crystal-like soft underlayer (SUL). The data recording layer and the servo layer may be on a same side of the crystal-like soft underlayer. | 01-30-2014 |
20140023823 | DIRECT DATA CONNECTORS FOR A SEALED DEVICE AND METHODS FOR FORMING A DIRECT DATA CONNECTOR FOR A SEALED DEVICE - According to various embodiments, a method for forming a direct data connector for a sealed device may be provided. The method may include: providing a substrate with a hole; and filling the hole with a filling material using a plating process. | 01-23-2014 |
20140022877 | METHODS FOR READING DATA FROM A STORAGE MEDIUM USING A READER AND STORAGE DEVICES - According to various embodiments, a method for reading data from a storage medium using a reader, wherein the reader includes at least one reader head, may be provided, wherein the storage medium includes a plurality of tracks. The method may include: reading a first signal with a reader head of the reader at a pre-determined position of the storage medium; reading a second signal with a reader head of the reader at the pre-determined position of the storage medium; and determining data stored at the pre-determined position of the storage medium based on the first signal and based on the second signal. | 01-23-2014 |
20140018694 | METHOD AND SYSTEM FOR MOTOR REHABILITATION - A method of calibrating a motor imagery detection module and a system for motor rehabilitation are provided. The method comprises acquiring Electroencephalography (EEG) data from a subject; selecting classification features from the EEG data; wherein the feature selection comprises modelling an idle state ω | 01-16-2014 |
20140017726 | MODIFIED HUMAN CMV PROMOTERS THAT ARE RESISTANT TO GENE SILENCING - The invention relates to a nucleic acid molecule comprising a functional promoter of a herpesvirus, a functional enhancer of a herpesvirus, and one or more internal elements of the CpG island of the aprt (adenine phosphoribosyl transferase) gene and/or a functional variant thereof. A method of producing a desired polypeptide using the nucleic acid molecule, a vector and a host cell containing the nucleic acid molecule are also disclosed. | 01-16-2014 |
20140017150 | MICROFLUIDIC DROPLET GENERATOR - A microfluidic droplet generator device, a kit of parts for assembling a microfluidic droplet generator device, and a method of generating microfluidic droplets. The generator device comprises a substrate; a microfluidic channel formed in the substrate; a fluid outlet in fluid communication with the microfluidic channel; and a mechanical element configured such that vibration of the mechanical element causes droplet dispensing from the fluid outlet. | 01-16-2014 |
20140015458 | Method and System for Controlling a Motor - A method and system for controlling a motor is provided. In particular, various embodiments of the present disclosure describe a method and system for controlling a spindle motor in a hard disk drive (HDD) A method of controlling a motor is provided, the motor including a 3-phase synchronous motor with three terminals of an electromagnetic winding configuration. The method includes providing an input voltage between two of the terminals and measures a resultant silent terminal voltage at the third terminal, which is thereafter used in determining a rotor position. A corresponding system for controlling a motor is further provided. | 01-16-2014 |
20140005396 | N-HETEROCYCLIC CARBENE METALLACYCLE CATALYSTS AND METHODS | 01-02-2014 |
20140004601 | METHOD OF PURIFYING EXOSOMES | 01-02-2014 |
20140004079 | IN VIVO DENDRITIC CELL THERAPEUTIC ADJUVANT | 01-02-2014 |
20140003723 | Text Detection Devices and Text Detection Methods | 01-02-2014 |
20140003126 | CIRCUIT ARRANGMENT AND A METHOD OF WRITING STATES TO A MEMORY CELL | 01-02-2014 |
20140001041 | BIOSENSOR | 01-02-2014 |
20130344140 | NOVEL PHARMACEUTICAL COMBINATIONS AND METHODS FOR TREATING CANCER - Methods of selectively targeting a p53-deficient cancer cell, comprising administering to a patient suffering from cancer (i) a reversible cell cycle arrest-inducing agent for inducing cell cycle arrest in a p53-positive cell; and (ii) an aurora kinase inhibitor, wherein said reversible cell cycle arrest-inducing agent is administered prior to administration of said aurora kinase inhibitor, and pharmaceutical combinations, kits and oral dosage forms for the same. | 12-26-2013 |
20130343454 | METHOD AND AN APPARATUS FOR CODING AN IMAGE - The present invention is directed to a method for coding an image, comprising generating from the image a residual block having a plurality of residual values using a coding mode; selecting a scanning pattern for scanning the residual block depending on the coding mode; scanning the residual values according to the scanning pattern; and generating a residual value stream from the scanned residual values. The present invention is also directed to a method of initializing a scanning pattern for coding an image, the method comprising collecting information on a coding mode applied to a residual block having a plurality of residual values; and assigning a directional scan in response to the information to form the scanning pattern. Apparatus for coding an image and for initializing a scanning pattern for coding an image are also disclosed. | 12-26-2013 |
20130343117 | WRITING CIRCUIT FOR A MAGNETORESISTIVE MEMORY CELL - According to embodiments of the present invention, a writing circuit for a magnetoresistive memory cell is provided. The writing circuit includes a first connecting terminal configured to provide a first electrical signal to switch a variable magnetization orientation of the free magnetic layer from a first magnetization orientation to a second magnetization orientation; a second connecting terminal configured to provide a second electrical signal to switch the magnetization orientation from the second magnetization orientation to the first magnetization orientation; and a sourcing switch configured to provide for a write operation a connection of the first or second connecting terminal to a node coupleable to the magnetoresistive memory cell. The first and second electrical signals have different amplitudes, and the first and second electrical signals are of the same polarity. Further embodiments relate to a memory cell arrangement and a method of writing into a target magnetoresistive memory cell. | 12-26-2013 |
20130343116 | WRITING CIRCUIT FOR A MAGNETORESISTIVE MEMORY CELL, MEMORY CELL ARRANGEMENT AND METHOD OF WRITING INTO A MAGNETORESISTIVE MEMORY CELL OF A MEMORY CELL ARRANGEMENT - A writing circuit for a magnetoresistive memory cell is provided. The writing circuit includes a first electrical connecting terminal, a second electrical connecting terminal, a third electrical connecting terminal, a fourth electrical connecting terminal, a first reference potential terminal, a second reference potential terminal, a first switch configured to couple one of the first electrical connecting terminal, the second electrical connecting terminal, the third electrical connecting terminal and the fourth electrical connecting terminal to the magnetoresistive memory cell, and a second switch configured to couple the first reference potential terminal to the magnetoresistive memory cell if the first electrical connecting terminal or the second electrical connecting terminal is coupled to the magnetoresistive memory cell, and to couple the second reference potential terminal to the magnetoresistive memory cell if the third electrical connecting terminal or the fourth electrical connecting terminal is coupled to the magnetoresistive memory cell. | 12-26-2013 |
20130338941 | METHOD AND APPARATUS FOR DEFECT DETECTION IN COMPOSITE STRUCTURES - Methods and apparatus for non-destructive testing of a composite structure utilizing sonic or ultrasonic waves. In response to a wideband chirp wave sonic excitation signal transmitted from a probe to the composite structure, a probe signal received is correlated with a library of predetermined probe signals and a graphical representation of defects detected is generated. The graphical representation provides detailed information on defect type, defect location and defect shape. Also contemplated is a probe for non-destructive testing of a composite structure comprising three or more transducers wherein each transducer is separately configurable as a transmitter or as a receiver; and a controller coupled to each of transducer for providing signals thereto and receiving signals therefrom, wherein the signals provided thereto include signals for configuring each transducer as either a transmitter or a receiver, and signals for providing an excitation signal from each transducer which is configured as a transmitter. | 12-19-2013 |
20130335843 | METHODS AND APPARATUS FOR HARD DISK DRIVE SYSTEM OPERATION MONITORING AND SELF-ADJUSTMENT - Methods and architecture for monitoring hard disk drive operation is provided. The hard disk drive system provided includes a spindle, a head and a disk with a disk medium including a buried servo layer having a first frequency of data on a first track and a second frequency of data on a second track, the second track adjacent to the first track. The method includes the steps of writing a wide track pattern having a predetermined frequency on a track of a hard disk drive medium, generating a readback signal by reading the pattern from the track, processing the readback signal by mixing the readback signal with a reference signal to obtain a mixed signal having a summed signal and a difference signal, and filtering the mixed signal by a filter centered around the difference signal to generate a measurement signal corresponding to a relative speed change of the spindle and a head-to-disk motion. In addition, filtering a readback signal generated by the head when positioned at the middle of the first track and the second track with a first filter centered at the first frequency and a second filter centered at the second frequency is used to generate signals for determining spindle speed variation, spindle speed jitter, and relative head-disk vibration in the downtrack direction, for synchronizing writing in Two Dimensional Magnetic Recording (TDMR) and for measuring continuous flying height information based on Wallace equations. | 12-19-2013 |
20130331727 | METHOD AND SYSTEM FOR DETECTING ATTENTION - A method and system for detecting attention of a subject is provided. The method comprises determining one or more user specific feature sets from Electroencephalographic (EEG) signals of the subject; determining one or more pool data feature sets from the EEG signals of the subject; identifying one or more features from each feature set for differentiating attention/non-attention signals; determining respective classification scores for each feature set based on the identified one or more features; and combining the classification scores to obtain a combined attention score for said detecting attention. | 12-12-2013 |
20130328431 | CYLINDRICAL ELECTROMAGNETIC ACTUATOR - A cylindrical-shape electromagnetic actuator comprising a plurality of pairs of magnets, the magnets of each pair being held at a distance from each other with an effective air gap formed therebetween for accommodating a coil structure; and a substantially cylindrical frame structure for supporting the pairs of magnets, the frame structure being configured such that substantially separate closed loop magnetic paths are provided for the respective pairs of magnets. | 12-12-2013 |
20130328209 | Stack Arrangement - In an embodiment, a stack arrangement is provided. The stack arrangement may include a semiconductor arrangement, the semiconductor arrangement including a substrate; a via formed through the substrate; and a conductive portion arranged in the via. The stack arrangement may further include an interconnect portion arranged over the via; a bond pad portion arranged between the semiconductor arrangement and the interconnect portion, the bond pad portion may include a bond pad circumferential portion arranged at least partially circumferential with respect to the via and at a first distance away from the conductive portion; and at least one bond pad electrical connection extending from within the bond pad circumferential portion to the conductive portion; wherein the interconnect portion may be arranged away from the conductive portion via the bond pad portion. | 12-12-2013 |
20130325473 | METHOD AND SYSTEM FOR DUAL SCORING FOR TEXT-DEPENDENT SPEAKER VERIFICATION - Embodiments of systems and methods for speaker verification are provided. In various embodiments, a method includes receiving an utterance from a speaker and determining a text-independent speaker verification score and a text-dependent speaker verification score in response to the utterance. Various embodiments include a system for speaker verification, the system comprising an audio receiving device for receiving an utterance from a speaker and converting the utterance to an utterance signal, and a processor coupled to the audio receiving device for determining speaker verification in response to the utterance signal, wherein the processor determines speaker verification in response to a UBM-independent speaker-normalized score. | 12-05-2013 |
20130324533 | METHOD OF DETECTING RESISTANCE TO CANCER THERAPY - We describe a polymorphic variant of a BIM {BCL2L11) gene which comprises, in 5′ to 3′ order, the nucleotide sequence set out in SEQ ID NO: 5 followed immediately by the nucleotide sequence set out in SEQ ID NO: 7. The BIM polymorphic variant may be characterised by lacking the nucleotide sequence set out in SEQ ID NO: 6. It may be used to detect BCR-ABL-independent TKI-resistance (resistance to treatment with tyrosine kinase inhibitors) for chronic myelogenous leukaemia, c-KIT/PDGFR-independent TKI-resistance for gastrointestinal stromal tumours (GIST), EGFR-independent TKI-resistance for non-small cell lung cancer (NSCLC) or JAK2-independent TKI-resistance for a myeloproliferative disorder, in an individual comprising such a polymorphism. | 12-05-2013 |
20130321905 | Multilayer Structure - A multilayer structure having a plurality of layers, with each layer being optically transparent over a selective wavelength range and being electrically conducting. The multilayer structure includes a top oxide layer having an exposed top surface that provides an outer surface of the multilayer structure and an inner surface that is opposite to the exposed top surface; a bottom oxide layer having an exposed bottom surface that provides an outer surface of the multilayer structure, which is opposite to the exposed top surface, and an inner surface that is opposite to the exposed bottom surface; a first control layer provided on the inner surface of the top oxide layer; and a second control layer provided on the inner surface of the bottom oxide layer, the first and the second control layers calibrated to have the multilayer structure attenuate light over two different wavelength ranges. | 12-05-2013 |
20130321027 | Circuit Arrangements and Methods of Operating the Same - In various embodiments, a circuit arrangement may be provided. The circuit arrangement may include a level shifting stage configured to be coupled to a first reference voltage, the level shifting stage having an output node. The circuit arrangement may further include a first input electrode in electrical connection with the level shifting stage. The circuit arrangement may also include a second input electrode in electrical connection with the level shifting stage. The circuit arrangement may further include a load having a first end and a second end, the first end coupled to the level shifting stage and the second end for coupling to a second reference voltage. In addition, the circuit arrangement may include a bypass circuit element connected in parallel to the load. The bypass circuit element may be configured to allow current to flow through upon application of an external voltage for bypassing the load. | 12-05-2013 |
20130316008 | MULTICOMPARTMENTALIZED VESICULAR STRUCTURE AND A METHOD FOR FORMING THE SAME - The present invention provides a method for forming a multicompartmentalized vesicular structure comprising an outer block copolymer vesicle and at least one inner block copolymer vesicle, wherein the at least one inner block copolymer vesicle is encapsulated inside the outer block copolymer vesicle. The method comprises forming the at least one inner block copolymer vesicle by any method and adding block copolymers dissolved in a suitable solvent to a dispersion of the at least one inner block copolymer vesicle in an aqueous buffer under conditions that allow the block copolymers to form the outer block copolymer vesicle and encapsulate the at least one inner block copolymer vesicle. A multicompartmentalized vesicular structure and its uses are also provided. | 11-28-2013 |
20130300521 | Piezoelectric Resonator - According to embodiments of the present invention, a piezoelectric resonator is provided. The piezoelectric resonator includes a piezoelectric substrate, a first electrode comprising a first plurality of electrode fingers, a second electrode comprising a second plurality of electrode fingers, wherein the first plurality of electrode fingers and the second plurality of electrode fingers are interdigitated, and wherein electrode patches are arranged along the first plurality of electrode fingers and the second plurality of electrode fingers according to a 2-dimensional lattice. | 11-14-2013 |
20130297675 | System For Learning Trail Application Creation - A server configured to create a learning trail application for a geographic area. The server includes a processor configured to: provide a template having a plurality of fields including a location field configured to receive the geographic area and an image archive field configured to receive images; receive template data for placement as the content of one or more of the plurality of fields; receive instructions for determining the placement of the template data into one or more of the plurality of fields; and generate the learning trail application from the template with the received template data. During execution of the application, the application is configured to receive at least one input image, determine whether a match exists between the input images and the content in the image archive field and display the template data associated with the content in the image archive field, when a match exists. | 11-07-2013 |
20130296188 | TARGETING METABOLIC ENZYMES IN HUMAN CANCER - Targeting metabolic enzymes in human cancer Abstract Lung cancer is a devastating disease and a major therapeutic burden with poor prognosis. The functional heterogeneity of lung cancer (different tumor formation ability in bulk of tumor) is highly related with clinical chemoresistance and relapse. Here we find that, glycine dehydrogenase (GLDC), one of the metabolic enzyme involved in glycine metabolism, is overexpressed in various subtypes of human lung cancer and possibly several other types of cancers. GLDC was found to be highly expressed in tumor-initiating subpopulation of human lung cancer cells compared with non-tumorigenic subpopulation. By array studies we showed that normal lung cells express low levels of GLDC compared to xenograft and primary tumor. Functional studies showed that RNAi inhibition of GLDC inhibits significantly the clonal growth of tumor-initiating cells in vitro and tumor formation in immunodeficient mice. Overexpression of GLDC in non-tumorigenic subpopulation convert the cells to become tumorigenic. Furthermore, over-expression of GLDC in NIH/3T3 cells and human primary lung fibroblasts can transform these cells, displaying anchorage-independent growth in soft agar and tumor-forming in mice. Not only is GLDC is expressed human lung cancer, it is also up-regulated in other types of cancer, such as colon cancer. RNAi knockdown of GLDC in colon cancer cell line, CACO-2 cells, can also inhibit the tumor formation in mice. Thus GLDC maybe a new metabolic target for treatment of lung cancer, and other cancers. | 11-07-2013 |
20130292586 | THz PHOTOMIXER EMITTER AND METHOD - A THz photomixer emitter is disclosed. The emitter comprises a photoconductive material, an antenna structure, and an electrode array. The electrode array is disposed such that an electric field associated with photocarriers generated in the photoconductive material is coupled to the antenna for emission of a THz wave via the antenna structure. The electrode array is configured such that an electric field resonance pattern of the electrode array is substantially aligned with an emission field pattern of the antenna structure. | 11-07-2013 |
20130288287 | FIBROUS STRUCTURE - A fibrous structure comprising an assembly of hair follicle cells within a fibrous matrix. | 10-31-2013 |
20130288225 | METHOD FOR SEPARATING WHOLE BLOOD - A method of separating blood by providing a horizontal substrate having a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film, depositing a whole blood sample on an upper surface of the substrate, collecting red blood cells on the upper surface of the pillars and permitting remaining components of said whole blood sample to flow downward and through the pillars. | 10-31-2013 |
20130287315 | METHOD, AN APPARATUS AND A COMPUTER PROGRAM PRODUCT FOR DEINTERLACING AN IMAGE HAVING A PLURALITY OF PIXELS - According to example embodiments, a method for deinterlacing an image having a plurality of pixels, the method comprising: calculating a difference between a first pixel of the image and each pixel of at least one pixel pair, each pixel pair comprising one pixel being positioned above the first pixel and another pixel being positioned below the first pixel; and deinterlacing the first pixel only if at least one difference corresponding to a pixel pair exceeds a predefined threshold. A corresponding apparatus and computer program product are also provided. | 10-31-2013 |
20130287296 | METHOD AND DEVICE FOR IMAGE PROCESSING - Embodiments provide a method for processing a first image based on a second image, wherein each pixel in the first image has a plurality of color components and has a corresponding pixel in the second image, and wherein each value of a color component in the first image corresponds to a value of a color component in the second image. The method may include deciding, for each color component of a pixel in the first image, whether to modify the value of the color component dependent on a predetermined criterion. The method may further include determining a similarity index between the pixel in the first image and the corresponding pixel in the second image based on, for each color component of the pixel, the value of the color component of the pixel, or if it is decided that the value of the color component of the pixel is to be modified, the corresponding value of the color component in the second image. | 10-31-2013 |
20130281515 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS - A cationic bis-urea compound is disclosed of formula (1): | 10-24-2013 |
20130281514 | TARGETING GLIOMA STEM CELLS BY SEQUENCE-SPECIFIC FUNCTIONAL INHIBITION OF PRO-SURVIVAL ONCOMIR-138 - Methods for malignant glioma diagnosis/prognosis using miR-138 as a prognostic biomarker and methods for treating malignant glioma and inhibiting glioma stem cell growth by suppressing miR-138. Also disclosed herein are pharmaceutical compositions for use in treating malignant glioma, prolonging survival of malignant glioma patients, or eliminating GSCs and in turn tumor growth, the pharmaceutical composition comprising an oligonucleotide that targets miR-138. | 10-24-2013 |
20130280719 | METHOD OF DERIVING PROGENITOR CELL LINE - We disclose a method comprising: (a) providing an embryonic stem (ES) cell; and (b) establishing a progenitor cell line from the embryonic stem cell; in which the progenitor cell line is selected based on its ability to self-renew. Preferably, the method selects against somatic cells based on their inability to self-renew. Preferably, the progenitor cell line is derived or established in the absence of co-culture, preferably in the absence of feeder cells, which preferably selects against embryonic stem cells. Optionally, the method comprises (d) deriving a differentiated cell from the progenitor cell line. | 10-24-2013 |
20130279237 | READING CIRCUIT FOR A RESISTIVE MEMORY CELL - A reading circuit for a resistive memory cell is provided, the circuit including a current source, a precharge switch, a comparator circuit including a first input node (in-node), and a second in-node, the precharge switch configured to couple the current source to the first in-node to apply a precharge voltage during a first reading time period, and to decouple the current source during a second reading time period, the comparator circuit configured to operate during a third reading time period, a memory cell access switch to enable a current flow at least partially during the second and the third reading time periods through a memory cell, the comparator circuit configured to compare a voltage at the first in-node with a reference voltage at the second in-node and to determine a programming state of the memory cell based on the voltage at the first in-node during the third reading time period. | 10-24-2013 |