Patent application title: EXTRACORPOREAL PERFUSION APPARATUS
Inventors:
Dieter Falkenhagen (Krems, AT)
Dieter Falkenhagen (Krems, AT)
Jens Hartmann (Furth, AT)
Stephan Harm (Furth, AT)
Assignees:
FRESENIUS MEDICAL CARE DEUTSCHLAND G.m.b.H.
IPC8 Class: AA61M134FI
USPC Class:
210 962
Class name: Liquid purification or separation constituent mixture variation responsive with membrane
Publication date: 2015-11-19
Patent application number: 20150328387
Abstract:
Embodiments of the invention relate to an extracorporeal perfusion
apparatus comprising an extracorporeal blood circuit for conveying blood,
a filtrate circuit for conveying blood plasma, and a controller, wherein
the filtrate circuit is connected to the extracorporeal blood circuit by
means of a filter, wherein the filter has a sieving coefficient of 5% for
substances having a molar mass of 340,000 g/mol (relative molecular mass
of 340 kDa), and wherein a depletion agent comprising a first carrier
having a neutral, hydrophobic surface is arranged in the filtrate
circuit, wherein the perfusion apparatus comprises a dispensing means for
feeding an endotoxin-binding lipopeptide into the extracorporeal blood
circuit, wherein the endotoxin-binding lipopeptide is selected from the
group consisting of polymyxins, polymyxin derivatives, prodrugs thereof,
and a combination thereof.Claims:
Description:
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| Top Inventors for class "Liquid purification or separation" | |
| Rank | Inventor's name |
|---|---|
| 1 | Robert W. Childers |
| 2 | Joseph A. King |
| 3 | John R. Hacker |
| 4 | Martin T. Gerber |
| 5 | Rodolfo Roger |