Zhenjun
Zhenjun Diwu, Okemos, MI US
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20090081722 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. The acetic acid groups interact directly with the positively charged histidine residues of the affinity tag to effectively label and detect a fusion protein containing such an affinity tag when present in an acidic or neutral environment. | 03-26-2009 |
20110027800 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings - The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes. | 02-03-2011 |
20120270757 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. | 10-25-2012 |
20120315661 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings - The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes. | 12-13-2012 |
20140038856 | Site-specific labeling of affinity tags in fusion proteins - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. The acetic acid groups interact directly with the positively charged histidine residues of the affinity tag to effectively label and detect a fusion protein containing such an affinity tag when present in an acidic or neutral environment. | 02-06-2014 |
Zhenjun Diwu, Alameda, CA US
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20120202220 | MULTIVALENT FLUORESCENT PROBES - Multivalent fluorescent probes and methods of using these multivalent fluorescent probes for in vitro and in vivo imaging are described. | 08-09-2012 |
20150209450 | MULTIVALENT FLUORESCENT PROBES - Multivalent fluorescent probes and methods of using these multivalent fluorescent probes for in vitro and in vivo imaging are described. | 07-30-2015 |
Zhenjun Wang, Xinxiang, Henan CN
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20160000077 | 2-Mercaptobenzothiazole Manganese Zinc, Preparation Method Therefor And Application Thereof - The present invention belongs to the technical field of agricultural fungicides and discloses a 2-mercaptobenzothiazole manganese zinc, preparation method therefor and application thereof. The chemical structure of the 2-mercaptobenzothiazole manganese zinc is shown as the above formula. Wherein m, n and n′ are positive integers, m=2(n+n′), n≧n′, n:n′=1:1˜9:1. Materials are prepared according to the stoichiometric ratio of the target products; 2-mercaptobenzothiazole is dissolved in sodium hydroxide solution. The aqueous solution of water-soluble manganese salts and water-soluble zinc salts solution are successively added to 2-mercaptobenzothiazole sodium solution under stirring, followed by stirring for mixing well, then the solution being allowed to stand, filtered and washed with water to obtain filter cake, and then dried in vacuum to obtain 2-mercaptobenzothiazole manganese zinc. The present 2-mercaptobenzothiazole manganese zinc may be used as an agricultural fungicide. The present invention coordinates the surface of solid particles of 2-mercaptobenzothiazole manganese with zinc to form a stable clathrate of 2-mercaptobenzothiazole manganese and zinc. Tests show that the clathrate has excellent effect for controlling a plurality of diseases including apple | 01-07-2016 |
Zhenjun Wang, Beijing CN
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20160101215 | PREPARATION METHOD FOR IMPLANTABLE MEDICAL BIOLOGICAL MATERIALS OF ANIMAL ORIGIN - The present invention provides a preparation method for implantable medical biological material of animal origin comprising the following procedures: Pre-processing, and washing of animal tissue materials; inactivation of virus; decellularizing cell; sodium chloride processing; molding and packaging sterilization. Cell-free ECM materials of animal origin produced by this method can achieve the goal of completely removing cell components of animal origin and composition of DNA, and at the same time, the natural ECM composition, three-dimensional structure and active growth factor which can induce and promote tissue regeneration retain. By using this process, endotoxin, organic solvents and toxic solvent residue are thus omitted and products with different sizes, thickness and mechanical strength can be formed. | 04-14-2016 |
Zhenjun Zhang, Beijing CN
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20130193687 | Rotor Device Of Integrated Stater-Generator Motor And Rotor Working System - A rotor device of an integrated starter-generator motor and a rotor working system are disclosed in the present invention. The rotor device is a monobloc casted and then machined, inseparable one-piece structure. The rotor device takes the shape of a straw hat and is provided with an external side surface of a hat top being surface ( | 08-01-2013 |
Zhenjun Zhu (alex), Redmond, WA US
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20120117481 | Partial Loading and Editing of Documents from a Server - On a client computer a request is sent to a server computer to open a first portion of a document. The document is stored at the server computer. The first portion of the document is smaller than the entire document. The request includes information used by the server computer to determine a size of the first portion of the document. The first portion of the document is received from the server computer. A second portion of the document is rendered on a display screen on the client computer. The second portion of the document is a subset of the first portion of the document. When the client computer determines that the user has scrolled a third portion of the document and that more of the document is available at the server computer, a second request is sent to the server computer to open an additional portion of the document. | 05-10-2012 |