Patent application number | Description | Published |
20100169096 | Instant communication with instant text data and voice data - Embodiments of the invention relate to an instant communication method, an instant communication server, a speech server and a system thereof. The instant communication method includes: receiving, by a speech server, text data sent via instant communication software by a first user terminal; transforming, by the speech server, the text data into first speech data; sending, by the speech server, the first speech data via a preconfigured phone number to a corresponding second user terminal; receiving, by the speech server, second speech data sent by the second user terminal; and sending, by the speech server, the second speech data to the first user terminal via the instant communication software. Using embodiments of the invention, website owners can communicate with visitors via a mobile phone or a fixed telephone anytime and anywhere, which may improve the reception of Internet marketing, reduce prerequisite requirements for e-commerce; and connect the Internet and the telecommunication network. | 07-01-2010 |
20100217734 | Method and system for calculating value of website visitor - Calculating a value of a website visitor includes initializing a calculation model for calculating the value of the website visitor, the calculation model being a neural network model with visitor information as an input and the visitor's value as an output; training the calculation model by using a data sample and determining the calculation model; and obtaining the visitor information, and calculating the value of the visitor by using the determined calculation model. | 08-26-2010 |
20110015951 | Evaluation of website visitor based on value grade - Evaluating website visitors includes: obtaining historical sample information of a plurality of past website visitors; based on the historical sample information, determining a plurality of value grades (cj) of the past website visitors and a respective plurality of rates of occurrence (P(cj)) for the plurality of value grades, wherein j=1, . . . , N, and N is an integer; determining a visitor characteristic probability (P(X)) and a plurality of conditional visitor characteristic probabilities given the plurality of value grades (P(X|cj)) associated with a current website visitor; and determining a plurality of conditional value grade probabilities given a visitor characteristic of the current website visitor ((P(c|X)) and selecting among the plurality of conditional value grade probabilities a likely value grade associated with the current website visitor, wherein j=1, . . . , N. | 01-20-2011 |
20110066697 | Promulgating Information on Websites Using Servers - A method uses web servers to promulgate information from one server to another, instead of promulgating the information by the user to each server individually. A first server receives a first request for promulgating web-information from a user, locally promulgates the web-information, and sends a second request to at least one second website server to instruct the second website server to locally promulgate the web-information. The selection of the second server is done according to a preset configuration file which includes a relationship mapping between the first website server and the second website server. The relationship mapping may provide the user information related to the second website server based on the user information related to the first website server. The present disclosure further discloses a communication apparatus and a communication system. | 03-17-2011 |
20110166926 | Evaluating Online Marketing Efficiency - A method and a system evaluate a company website's online marketing efficiency on various advertising websites by evaluating both access activities and business activities of users originating from the advertising websites. For each user visiting the company website, the method determines the originating website from which the user enters the company website, and obtains the access activities and the business activities of the user on the company website. The method quantifies the access activities and the business activities of the users who enter the present website from the same originating website to generate evaluation data corresponding to the originating website, and evaluates the company website's online marketing efficiency on the originating website based on the evaluation data of the originating website. Using the disclosed method and system, online marketing efficiency can be evaluated more comprehensively and accurately. | 07-07-2011 |
20120166315 | System and Method of Optimal Time for Product Launch and Withdraw in E-Commerce - The present disclosure introduces a technique for achieving the optimal time to launch or withdraw products on a webpage. In one aspect, a method includes: storing information to be collected from a webpage for one or more items corresponding to a first product; collecting data related to the one or more items in each time section of a plurality of time sections; calculating a respective value score for each time section of the plurality of time sections based on a respective number of occurrences of the one or more items in each time section; determining the optimal time to launch or withdraw the first product based on value scores of the first product for the plurality of time sections; and rendering launch or withdrawal of the first product on the webpage in the optimal time. Implementation of the technique will conveniently allow a merchant's product website to automatically complete a product launch or withdrawal in the optimal time. | 06-28-2012 |
20130218702 | SYSTEM AND METHOD OF OPTIMAL TIME FOR PRODUCT LAUNCH AND WITHDRAW IN E-COMMERCE - The present disclosure introduces a technique for achieving the optimal time to launch or withdraw products on a webpage. In one aspect, a method includes: storing information to be collected from a webpage for one or more items corresponding to a first product; collecting data related to the one or more items in each time section of a plurality of time sections; calculating a respective value score for each time section of the plurality of time sections based on a respective number of occurrences of the one or more items in each time section; determining the optimal time to launch or withdraw the first product based on value scores of the first product for the plurality of time sections; and rendering launch or withdrawal of the first product on the webpage in the optimal time. Implementation of the technique will conveniently allow a merchant's product website to automatically complete a product launch or withdrawal in the optimal time. | 08-22-2013 |
20150271012 | PROMULGATING INFORMATION ON WEBSITES USING SERVERS - A method uses web servers to promulgate information from one server to another, instead of promulgating the information by the user to each server individually. A first server receives a first request for promulgating web-information from a user, locally promulgates the web-information, and sends a second request to at least one second website server to instruct the second website server to locally promulgate the web-information. The selection of the second server is done according to a preset configuration file which includes a relationship mapping between the first website server and the second website server. The relationship mapping may provide the user information related to the second website server based on the user information related to the first website server. The present disclosure further discloses a communication apparatus and a communication system. | 09-24-2015 |
Patent application number | Description | Published |
20090149673 | SYNTHETIC NON-FOULING AMINO ACIDS - Synthetic amino acids containing one or more non-fouling groups or moieties are described herein. In one embodiment, the amino acid has the following chemical formula: | 06-11-2009 |
20090155335 | NON-LEACHING NON-FOULING ANTIMICROBIAL COATINGS - Compositions containing one or more types of membrane-targeting antimicrobial agents immobilized on a substrate with activity in relevant biological environments, and methods of making and using thereof, are described herein. The antimicrobial agents retain their activity in the presence of blood proteins and/or in vivo due to improved molecular structures which allow for cooperative action of immobilized agents and hydrophilic chemistries which resist non-specific protein adsorption. Suitable molecular structures include branched structures, such as dendrimers and randomly branched polymers. The molecule structures may also include hydrophilic tethers which provide both flexibility and resistance to non-specific protein adsorption. The membrane targeting antimicrobial agent coatings can be applied to a variety of different types of substrates including medical implants such as vascular grafts, orthopedic devices, dialysis access grafts, and catheters; surgical tools, surgical garments; and bandages. The substrates can be composed of metallic materials, ceramics, polymers, fibers, inert materials such as silicon, and combinations thereof. The compositions described herein are substantially non-leaching, resistant to non-specific protein adsorption, and non-hemolytic. | 06-18-2009 |
20090156460 | CATIONIC BETAINE PRECURSORS TO ZWITTERIONIC BETAINES HAVING CONTROLLED BIOLOGICAL PROPERTIES - Cationic polymers hydrolyzable to zwitterionic polymers, monomers for making the cationic polymers, surfaces that include the polymers, therapeutic agent delivery systems that include the cationic polymers, methods for administering a therapeutic agent using the delivery systems, and methods for making and using the cationic polymers, monomers, surfaces, and therapeutic agent delivery systems. | 06-18-2009 |
20100099160 | DUAL-FUNCTIONAL NONFOULING SURFACES AND MATERIALS - Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery. | 04-22-2010 |
20100145286 | LAYERED NON-FOULING, ANTIMICROBIAL ANTITHROMBOGENIC COATINGS - Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material | 06-10-2010 |
20100152708 | NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT-FROM COMPOSITIONS - Substrates, optionally coated with an undercoating layer, having grafted there from one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted from a variety of substrate materials, particularly polymeric substrates and/or polymeric undercoating layers. The graft-from techniques described herein can result in higher surface densities of the non-fouling material relative to graft-to formulations. Graft-from methods can be used to produce covalently tethered polymers. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted from the substrate, or optionally from an undercoating layer on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material. | 06-17-2010 |
20110282005 | SUPER-LOW FOULING SULFOBETAINE MATERIALS AND RELATED METHODS - Super-low fouling sulfobetaine and carboxybetaine materials, super-low fouling surfaces and methods of making the surfaces coated with sulfobetaine and carboxybetaine materials, and devices having the super-low fouling surfaces. | 11-17-2011 |
20110305872 | NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT-FROM COMPOSITONS - A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm | 12-15-2011 |
20110305881 | ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME INCLUDING APPLYING A PRIMER COAT - Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve coating the substrate to conceal or reduce flaws on or in the surface of the medical device or other article substrate, and thereafter forming a grafted polymer layer on the treated substrate surface. | 12-15-2011 |
20110305895 | ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME INCLUDING PRETREATMENT OF ARTICLES - Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface. | 12-15-2011 |
20110305898 | NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT COMPOSITIONS - The present invention generally relates to articles of manufacture, such as medical devices, having a non-fouling surface comprising a grafted polymer material. The surface resists the adhesion of biological material. | 12-15-2011 |
20110305909 | ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME WITHOUT ALTERING BULK PHYSICAL PROPERTIES - Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface. | 12-15-2011 |
20130011363 | CATIONIC BETAINE PRECURSORS TO ZWITTERIONIC BETAINES HAVING CONTROLLED BIOLOGICAL PROPERTIES - Cationic polymers hydrolyzable to zwitterionic polymers, monomers for making the cationic polymers, surfaces that include the polymers, therapeutic agent delivery systems that include the cationic polymers, methods for administering a therapeutic agent using the delivery systems, and methods for making and using the cationic polymers, monomers, surfaces, and therapeutic agent delivery systems. | 01-10-2013 |
20130155370 | SURFACE MODIFIED CONTACT LENSES - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 06-20-2013 |
20130155371 | REDOX PROCESSES FOR CONTACT LENS MODIFICATION - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 06-20-2013 |
20130158150 | MULTISTEP UV PROCESS TO CREATE SURFACE MODIFIED CONTACT LENSES - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 06-20-2013 |
20130158211 | IMBIBING PROCESS FOR CONTACT LENS SURFACE MODIFICATION - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 06-20-2013 |
20130158488 | LUMINAL MODIFICATIONS FOR CATHETERS - Catheters and a method of preparation thereof comprising a catheter body and at least one connector. The catheter body has an exterior surface and at least one lumen having an aspect ratio of at least 3:1 and an intraluminal surface comprising a hydrophilic polymer layer thereon, the hydrophilic polymer layer has an average dry thickness of at least about 50 nanometers. | 06-20-2013 |
20130158517 | SURFACE MODIFICATION FOR DIALYSIS CATHETERS - Catheters and a method of preparation thereof, the catheter comprising a catheter body, a juncture hub, extension lines and connectors, the catheter body having a proximal end, a distal end, an exterior surface, a tip region having a length of 10 cm measured from the distal end of the catheter body, and at least two lumen, each of the catheter body lumen having a proximal end, a distal end, a Lumen Aspect Ratio of at least 3:1, and an intraluminal surface, the distal ends of the at least two catheter body lumen being (i) non-coterminus or (ii) laser-cut, the exterior surface of the catheter body in the tip region or the intraluminal surface of the two catheter body lumen comprising a hydrophilic polymer layer having an Average Dry Thickness of at least about 50 nanometers. | 06-20-2013 |
20130158518 | SURFACE MODIFICATION FOR CATHETERS COMPRISED OF MULTIPLE MATERIALS - Catheters and a method for preparation thereof, the catheter comprising as component parts thereof a catheter body, a juncture hub, at least one extension line and at least one connector, each of said component parts comprising an exterior surface, at least one lumen having an intraluminal surface and a bulk polymer, wherein the intraluminal or external surface of a first of said component parts and the exterior or intraluminal surface of a second of said component parts comprise a hydrophilic polymer layer thereon having an Average Dry Thickness of at least about 50 nanometers and the first and second component parts comprise bulk polymers having different chemical compositions | 06-20-2013 |
20130176529 | SILICONE HYDROGEL CONTACT LENS MODIFIED USING LANTHANIDE OR TRANSITION METAL OXIDANTS - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 07-11-2013 |
20130188124 | HIGH IONIC STRENGTH PROCESS FOR CONTACT LENS MODIFICATION - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 07-25-2013 |
20140037967 | ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME INCLUDING PRETREATMENT OF ARTICLES - Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface. | 02-06-2014 |
20140045398 | LAYERED NON-FOULING, ANTIMICROBIAL ANTITHROMBOGENIC COATINGS - Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material | 02-13-2014 |
20140235803 | PARTICLES COATED WITH ZWITTERIONIC POLYMERS - Nanoparticles zwitterionic polymers grafted thereto or grafted therefrom, and methods for making and using the nanoparticles. Zwitterionic nanogels, and methods for making and using the nanogels. | 08-21-2014 |
20140370567 | DUAL-FUNCTIONAL NONFOULING SURFACES COMPRISING TARGET BINDING PARTNER COVALENTLY COUPLED TO POLYMER ATTACHED TO SUBSTRATE - Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery. | 12-18-2014 |
20150045515 | NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT-FROM COMPOSITIONS - A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm | 02-12-2015 |
20150056411 | NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT COMPOSITIONS - The present invention generally relates to articles of manufacture, such as medical devices, having a non-fouling surface comprising a grafted polymer material. The surface resists the adhesion of biological material. | 02-26-2015 |
Patent application number | Description | Published |
20110270533 | SYSTEMS AND METHODS FOR ANALYZING NUCLEIC ACID SEQUENCES - Nucleic acid sequence mapping/assembly methods are disclosed. The methods initially map only a contiguous portion of each read to a reference sequence and then extends the mapping of the read at both ends of the mapped contiguous portion until the entire read is mapped (aligned). In various embodiments, a mapping score can be calculated for the read alignment using a scoring function, score (i, j)=M+mx, where M can be the number of matches in the extended alignment, x can be the number of mismatches in the alignment, and m can be a negative penalty for each mismatch. The mapping score can be utilized to rank or choose the best alignment for each read. | 11-03-2011 |
20120011086 | SYSTEMS AND METHODS FOR SEQUENCE DATA ALIGNMENT QUALITY ASSESSMENT - A computer-implemented method for classifying alignments of paired nucleic acid sequence reads is disclosed. A plurality of paired nucleic acid sequence reads is received, wherein each read is comprised of a first tag and a second tag separated by an insert region. Potential alignments for the first and second tags of each read to a reference sequence is determined, wherein the potential alignments satisfies a minimum threshold mismatch constraint. Potential paired alignments of the first and second tags of each read are identified, wherein a distance between the first and second tags of each potential paired alignment is within an estimated insert size range. An alignment score is calculated for each potential paired alignment based on a distance between the first and second tags and a total number of mismatches for each tag. | 01-12-2012 |
20120203792 | SYSTEMS AND METHODS FOR MAPPING SEQUENCE READS - Systems, methods, and computer program products for aligning a fragment sequence to a target sequencing. The alignment is allowed at most one gap, such as an insertion or a deletion. In some embodiments, both a gapped alignment and an ungapped alignment can be produced. A selection can be made between the gapped alignment and the ungapped alignment based on a quality value for each alignment. | 08-09-2012 |
20120259556 | SYSTEM AND METHODS FOR INDEL IDENTIFICATION USING SHORT READ SEQUENCING - Systems, methods, and analytical approaches for short read sequence assembly and for the detection of insertions and deletions (indels) in a reference genome. A method suitable for software implementation is presented in which indels may be readily identified in a computationally efficient manner. | 10-11-2012 |
20130073214 | SYSTEMS AND METHODS FOR IDENTIFYING SEQUENCE VARIATION - Systems and method for determining variants can receive mapped reads, and call variants. In embodiments, flow space information for the reads can be aligned to a flow space representation of a corresponding portion of the reference. Reads spanning a position with a potential variant can be grouped and a score can be calculated for the variant. Based on the scores, a list of probable variants can be provided. In various embodiments, low frequency variants can be identified where multiple potential variants are present at a position. | 03-21-2013 |
20130261005 | SYSTEM AND METHODS FOR INDEL IDENTIFICATION USING SHORT READ SEQUENCING - Systems, methods, and analytical approaches for short read sequence assembly and for the detection of insertions and deletions (indels) in a reference genome. A method suitable for software implementation is presented in which indels may be readily identified in a computationally efficient manner. | 10-03-2013 |
20130345066 | SYSTEMS AND METHODS FOR IDENTIFYING SEQUENCE VARIATION - Systems and method for determining variants can receive mapped reads, align flow space information to a flow space representation of a corresponding portion of the reference. Reads spanning a position with a potential variant can be evaluated in a context specific manner. A list of probable variants can be provided. | 12-26-2013 |