Patent application number | Description | Published |
20090170905 | SOLID FORMS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID - The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith. | 07-02-2009 |
20100130547 | SOLID FORMS OF N-(4-(7-AZABICYCLO[2.2.1]HEPTAN-7-YL)-2-(TRIFLUORORMETHYL)PHENYL)-4-OXO-5- -(TRIFLUOROMETHYL)-1,4-DIHYROQUINOLINE-3-CARBOXAMIDE - The present invention relates to solid state forms, for example, crystalline forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, pharmaceutical compositions thereof, and methods therewith. | 05-27-2010 |
20110123449 | Solid Forms of N-(4-(7-Azabicyclo[2.2.1]Heptan-7-yl)-2-Trifluoromethyl)Phenyl)-4-Oxo-5-(- Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxamide - The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith. | 05-26-2011 |
20110251253 | SOLID FORMS OF (R)-1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6- -FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL) CYCLOPROPANECARBOXAMIDE - The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith. | 10-13-2011 |
20110263654 | SOLID FORMS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID - The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 10-27-2011 |
20120277268 | SOLID FORMS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID - The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith. | 11-01-2012 |
20130085158 | SOLID FORMS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID - The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 04-04-2013 |
20130131107 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formulas I and II, optionally in combination with a Compound of Formula III and/or a Compound of Formula IV. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 05-23-2013 |
20130137722 | SOLID FORMS OF N-(4-(7-AZABICYCLO[2.2.1]HEPTAN-7-YL)-2-TRIFLUOROMETHYL)PHENYL)-4-OXO-5-(- TRIFLUOROMETHYL)-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE - The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith. | 05-30-2013 |
20130143918 | Solid Forms of (R)-1(2,2-Difluorobenzo[D][1,3]Dioxol-5-yl)-N-(1-(2,3-Dihydroxypropyl-6-F- luoro-2-(1-Hydroxy-2-Methylpropan-2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxa- mide - The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith. | 06-06-2013 |
20130143919 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 06-06-2013 |
20130158071 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 06-20-2013 |
20130231368 | Solid Forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5- -(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide - The present invention relates to solid state forms, for example, crystalline forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, pharmaceutical compositions thereof, and methods therewith. | 09-05-2013 |
20130296379 | Solid Forms of 3-(6-(1-(2,2-Difluorobenzo[D][1,3]Dioxol-5-yl)Cyclopropanecarboxamido)-3-- Methylpyridin-2-yl)Benzoic Acid - The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 11-07-2013 |
20130338188 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 12-19-2013 |
20140011846 | Solid Forms of 3-(6-(1-(2,2-Difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-- methylpyridin-2-yl) Benzoic Acid - The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith. | 01-09-2014 |
20140113933 | Solid Forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-- (trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide - The present invention relates to solid state forms, for example, crystalline forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, pharmaceutical compositions thereof, and methods therewith. | 04-24-2014 |
20140221430 | Solid Forms of 3-(6-(1-(2,2-Difluorobenzo[D][1,3]Dioxol-5-yl)Cyclopropanecarboxamido)-3-- Methylpyridin-2-yl)Benzoic Acid - The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 08-07-2014 |
20140371275 | SOLID FORMS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-- METHYLPYRIDIN-2-YL) BENZOIC ACID - The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith. | 12-18-2014 |
Patent application number | Description | Published |
20100296502 | I-Q MISMATCH COMPENSATION - Techniques for compensating for I-Q mismatch in a communications receiver. In an exemplary embodiment, incoming I and Q samples are adjusted by multiplying with certain compensation coefficients to generate mismatch-compensated I and Q samples. The compensation coefficients may themselves be calculated and iteratively refined from the mismatch-compensated I and Q samples. Further techniques for partitioning the adjustment and estimation functions among computational hardware are disclosed. In an exemplary embodiment, estimation may be restricted to only those segments of the incoming I and Q samples that fulfill certain conditions, e.g., segments of the incoming I and Q samples known to be statistically uncorrelated and/or to have equal average energy. | 11-25-2010 |
20110136446 | COMBINED INTELLIGENT RECEIVE DIVERSITY (IRD) AND MOBILE TRANSMIT DIVERSITY (MTD) WITH INDEPENDENT ANTENNA SWITCHING FOR UPLINK AND DOWNLINK - Methods and apparatus are provided for allowing a transmitter (Tx) to perform antenna selection independently of a receiver (Rx) in a transceiver supporting both transmit diversity and receive diversity. Certain aspects may utilize a cross switch, which may be used in a parallel or cross configuration, to provide for the independent antenna selection, such that the Rx may maintain the ability to operate on the same antenna as the Tx, on another antenna, or on both antennas for enhanced receive diversity. Furthermore, certain aspects may employ additional switching in the baseband domain in an effort to avoid, or at least reduce, switching glitches in the Rx caused by changing the cross switch configuration. In this manner, the Rx need not re-converge upon antenna switching. | 06-09-2011 |
20110244912 | METHOD AND APPARATUS FOR MAXIMUM RATIO TRANSMISSION MOBILE TRANSMIT DIVERSITY SYSTEM - A method and apparatus for providing maximum ratio transmission mobile transmit diversity is provided. The method may include selecting a first transmit power for a first antenna and a second transmit power for a second antenna, wherein the first and second transmit powers are selected to generate a target power output, and using a first average power tracking unit to generate the first selected transmit power and a second average power tracking unit to generate the second selected transmit power. | 10-06-2011 |
20110286347 | UE Based Conditional Enabling of ULTD - In a communication system, user equipment (UE) conditionally performs uplink transmit diversity (ULTD) either by Switched Antenna Transmit Diversity (SATD) or Beamforming Transmit Diversity (BFTD) using a first antenna and a second antenna. Either a serving node or the UE determines that uplink transmit diversity is conditionally authorized. Either a serving node or the UE measures a value. The UE transmits using ULTD in response to determining that an enabling condition based on the value is satisfied. The UE can also disable uplink transmit diversity in response to determining that a disabling condition based on the value is satisfied. The disabling condition comprises a disabling threshold that equals the enabling condition comprising an enabling threshold with a threshold adjustment for hysteresis. | 11-24-2011 |
20140302803 | COMBINED INTELLIGENT RECEIVE DIVERSITY (IRD) AND MOBILE TRANSMIT DIVERSITY (MTD) WITH INDEPENDENT ANTENNA SWITCHING FOR UPLINK AND DOWNLINK - Methods and apparatus are provided for allowing a transmitter (Tx) to perform antenna selection independently of a receiver (Rx) in a transceiver supporting both transmit diversity and receive diversity. Certain aspects may utilize a cross switch, which may be used in a parallel or cross configuration, to provide for the independent antenna selection, such that the Rx may maintain the ability to operate on the same antenna as the Tx, on another antenna, or on both antennas for enhanced receive diversity. Furthermore, certain aspects may employ additional switching in the baseband domain in an effort to avoid, or at least reduce, switching glitches in the Rx caused by changing the cross switch configuration. In this manner, the Rx need not re-converge upon antenna switching. | 10-09-2014 |
Patent application number | Description | Published |
20090103547 | AUTOMATIC CONFIGURATION OF WIRELESS DEVICE FOR ROUTER - A user of a wireless device connects a cable to a router and is given the option of manually or automatically creating a user profile to configure the wireless device for subsequent wireless communication with the router when the user removes the cable. | 04-23-2009 |
20090158216 | METHOD AND SYSTEM FOR SETTING UP A COMPUTER SYSTEM AT STARTUP - A graphical user interface (GUI) for setting up a computer system at startup. The GUI may include a first plurality of on-screen selectable icons, wherein each of the first plurality of on-screen selectable icons is associated with at least one respective setup procedure that when invoked causes a processor to execute an associated setup functionality. The GUI further includes a first visual indicator operable to identify one of the first plurality of on-screen selectable icons responsive to a user selection thereof. A second visual indicator may be used to identify a completion of a setup procedure associated with the user selection of the one of the first plurality of on-screen selectable icons. The GUI also includes a plurality of on-screen navigational icons for navigating through the first plurality of on-screen selectable icons, for canceling a selection and for exiting a startup user experience. | 06-18-2009 |
20110107137 | System and method for providing automated support to electronic devices - A system and method for providing automated support services includes at least one electronic device that experiences an error condition. An error notification regarding the error condition is then provided to a support server. The support server assigns an error identifier to the error condition, and provides the error identifier to the electronic device. The support server also creates a solution map that associates the error identifier with a solution identifier corresponding to an effective solution for the detected error condition. A solution database is implemented to store the solution to the error condition. A solution manager of the electronic device may then utilize the error identifier to automatically identify, download, and install the solution from the solution database to thereby remedy the error condition. | 05-05-2011 |
20120102384 | PRODUCT INFORMATION MANAGEMENT AND AUTOMATION - A series of UIs is presented on a computer display to allow a user to select one or more sources of help for various aspects of the computer. The user can select to have presented hyperlinks to obtain help information from the manufacturer of the computer, from the O.S. provider, and from third party providers of applications executable by the computer. | 04-26-2012 |
20120116981 | METHODS AND SYSTEMS FOR MAINTAINING PRIVACY OF CUSTOMER CARE METRICS - Systems and methods consistent with the invention relate to providing customer care metrics. According to one exemplary embodiment, a computer-implemented method for generating customer care metrics associated with a terminal device is disclosed. The method receives a first set of customer care data including identity information of the terminal device. The method electronically integrates the first set of customer care data with a second set of customer care data collected from the terminal device, to produce a set of integrated data. The method also removes the identity information from the set of integrated data, and generates customer care metrics based on the integrated data. | 05-10-2012 |
20120117097 | SYSTEM AND METHOD FOR RECOMMENDING USER DEVICES BASED ON USE PATTERN DATA - An apparatus and method for utilizing user feedback of a user device. The method includes obtaining use pattern data of a user's use patterns and performing use pattern analysis based on the use pattern data. A customized setting is generated based on the result of the use pattern analysis. A customized product recommendation is designed based on the customized setting and upgraded based on the customized setting. | 05-10-2012 |
20120117139 | METHOD AND APPARATUS FOR OBTAINING FEEDBACK FROM A DEVICE - A method and apparatus for providing a user device with data based on user feedback from the user device. The method includes obtaining usage data of the user device using an application programming interface (API) and creating a data file based on the obtained usage data. The data file is uploaded from the user device to an external server device and data analysis of the data file is performed. The user device is provided with selected data based on data analysis of the data file. | 05-10-2012 |
20120117189 | METHOD AND APPARATUS FOR OBTAINING FEEDBACK FROM A DEVICE - An apparatus and method for utilizing user feedback of a user device. The method includes identifying state information of the CPU and obtaining usage information when the CPU is identified to be in a processing state. The average CPU usage is calculated and the CPU is upgraded based on the calculated average. | 05-10-2012 |
20120117227 | METHOD AND APPARATUS FOR OBTAINING FEEDBACK FROM A DEVICE - An apparatus and method for utilizing user feedback of a user device. The method includes obtaining usage data of a user device using an application programming interface (API) and creating a data file based on the obtained usage data. The data file is uploaded from the user device to an external server device where data analysis of the data file is performed and a result of the data analysis is generated. This result is presented using a display unit. | 05-10-2012 |
20120117425 | METHOD AND APPARATUS FOR OBTAINING FEEDBACK FROM A DEVICE FOR RECOMMENDATIONS - A system and method for utilizing user feedback of a user device. The method includes accessing a troubleshooting request for a user device and obtaining use pattern data of a user's use pattern of the user device. Operational setting information of the user device is obtained. Next, analysis of the use pattern data and the operational setting information of the user device is performed. A customized troubleshooting step list is generated, which is based on the analysis. A plurality of troubleshooting steps is performed in a sequence based on the customized troubleshooting step list. | 05-10-2012 |
20120117576 | METHOD AND APPARATUS FOR OBTAINING FEEDBACK FROM A DEVICE - A method and apparatus for providing a user device with data based on user feedback from the user device. The method includes obtaining usage data of the user device using an application programming interface (API). A data file is generated or created based on the obtained usage data and the data file is uploaded from the user device to an external server device where data analysis of the data file is performed. The results of the analysis is used to increase user device performance. | 05-10-2012 |
20130124926 | SYSTEM HEALTH AND PERFORMANCE CARE OF COMPUTING DEVICES - A system and computer program product for system care for a computing device. In one embodiment, a process includes analyzing one or more software and hardware components of the computing device by a system care program of the computing device, analyzing system health of the computing device based on the one or more software and hardware components based on at least one of status and settings of the one or more software and hardware components, and analyzing performance of the computing device based on the one or more software and hardware components based on signature profiles of the one or more software and hardware components The process may also include determining one or more solutions for the computing device by the system care program based on the system health and performance of the computing device, and displaying a report including the one or more solutions. | 05-16-2013 |
20130254167 | SYSTEM AND METHOD FOR AUTOMATIC DETECTION OF DUPLICATE DIGITAL PHOTOS - Hashes of metadata of digital photographs on, e.g., a removable camera memory are compared against values in a hash table representing previously stored photographs on an archive computer to ensure that only previously unstored photos are copied onto the archive computer. | 09-26-2013 |
Patent application number | Description | Published |
20080261295 | Cell Sorting System and Methods - Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on a switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format. Optical and/or fluidic switching forces are used alone or in combination to effect switching. | 10-23-2008 |
20090042737 | Methods and Devices for Correlated, Multi-Parameter Single Cell Measurements and Recovery of Remnant Biological Material - Methods and apparatus are provided for analysis and correlation of phenotypic and genotypic information for a high throughput sample on a cell by cell basis. Cells are isolated and sequentially analyzed for phenotypic information and genotypic information which is then correlated. Methods for correlating the phenotype-genotype information of a sample population can be performed on a continuous flow sample within a microfluidic channel network or alternatively on a sample preloaded into a nano-well array chip. The methods for performing the phenotype-genotype analysis and correlation are scalable for samples numbering in the hundreds of cells to thousands of cells up to the tens and hundreds of thousand cells. | 02-12-2009 |
20100304429 | METHODS AND APPARATUS FOR SORTING CELLS USING AN OPTICAL SWITCH IN A MICROFLUIDIC CHANNEL NETWORK - Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on an optical switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format. | 12-02-2010 |
20110086769 | METHODS AND GENOTYPING PANELS FOR DETECTING ALLELES, GENOMES, AND TRANSCRIPTOMES - Disclosed are methods and genotyping panels for detecting alleles, genomes, and transcriptomes in admixtures of two individuals. | 04-14-2011 |
20120077191 | GENOTYPING DNA - Described herein are compositions and methods useful for the detection of nucleic acid variations. Ligation within a probe or between probes is used to distinguish between probes perfectly complementary to a target and those containing a mismatch. Nucleotide fill-in/extension steps are optionally applied according to the type of assay performed. A circularization and relinearization step can be applied to create a template for further amplification and detection. In certain aspects, portions of a target sequence or its complement are not amplified. | 03-29-2012 |
20140295419 | METHODS AND COMPOSITIONS FOR ISOTHERMAL WHOLE GENOME AMPLIFICATION - Disclosed are methods and compositions for amplification of genetic material, including isothermal WGA of single cells. | 10-02-2014 |
20140371083 | SYSTEMS, APPARATUS AND METHODS FOR BIOCHEMICAL ANALYSIS - Systems, apparatus and methods are provided for biochemical analysis of a sample (e.g., a cell or nucleic acids). Samples are analyzed for molecular information and remain accessible for subsequent analysis or testing. The systems, apparatus and methods and systems provided are useful for performing quantitative and highly parallel biochemical reactions on biological samples in a high-throughput manner. | 12-18-2014 |
20150024476 | CELL SORTING SYSTEM AND METHODS - Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on a switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., | 01-22-2015 |
Patent application number | Description | Published |
20120166799 | SYSTEM AND METHOD FOR SECURELY MOVING CONTENT - A domain controller is provided for use with a content source and a media device. The content source can provide encrypted content and rights data corresponding to the encrypted content. The media device can provide a request for the encrypted content and the rights data. The domain controller includes a communication portion, a digital rights management portion and a memory portion. The communication portion can engage in a first bi-directional communication with the content source and can engage in a second bi-directional communication with the media device. The digital rights management portion can receive the rights data. The memory portion can store the encrypted content. The second bi-directional communication includes an authorization and authentication communication between the communication portion and the media device, a secure move message exchange between the communication portion and the media device and a content download from the communication portion to the media device. | 06-28-2012 |
20120185693 | SECURE PROGRESSIVE DOWNLOAD FOR MEDIA CONTENT PLAYBACK - In embodiments of secure progressive download for media content playback, a client device ( | 07-19-2012 |
20130091353 | APPARATUS AND METHOD FOR SECURE COMMUNICATION - A method and apparatus are for transferring a client device certificate and an associated encrypted client private key to a client device from a secure device. The secure device receives over a secure connection, a secure device certificate, a secure device private key and a plurality of client device certificates. Each client certificate is associated with a bootstrap public key but is not assigned to any particular client device. A plurality of encrypted client private keys is also received. Each of the encrypted client private keys comprises a client private key associated with one of the client device certificates encrypted with the bootstrap public key. The plurality of client device certificates is stored. The encrypted client private keys are stored in double encrypted protected form. A client device certificate and an associated encrypted client private key are transferred to a client device that has successfully registered with the secure device. | 04-11-2013 |
20130102253 | DISTRIBUTED CONTROL OF MEDICAL DEVICES TO AVOID EFFECTS OF INTERFERENCE - Certain aspects of the present disclosure provide techniques and apparatus for transmitting relatively more critical information between devices using a first wireless technology and transmitting relatively less critical information using a second wireless technology more susceptible to interference than the first wireless technology. One example method generally includes performing an association with a second apparatus via a first wireless technology, wherein the first wireless technology requires proximity between the first and second apparatuses; communicating first information with the second apparatus via the first wireless technology, a second wireless technology, or a combination of both the first and second wireless technologies, while the first and second apparatuses are still in proximity; and communicating second information with the second apparatus via the second wireless technology. | 04-25-2013 |
20130102963 | SECURE AUTOMATIC CONFIGURATION OF EQUIPMENT THROUGH REPLICATION - Certain aspects of the present disclosure provide techniques and apparatus for secure automatic configuration of equipment through replication. One example method generally includes receiving a request for configuration information used to configure at least a first device to be replicated in at least a second device; and communicating the configuration information to the second device, in response to the request. At least one of the first and second wireless devices may be a medical device, and/or the configuration information may include patient treatment information. In this manner, the amount of configuration data entry by a caregiver and the number of errors in this configuration data are most likely considerably reduced. Furthermore, in an emergency, a common medical treatment may be easily configured for many patients at once (i.e., the configuration information may be easily replicated from patient device to patient device). | 04-25-2013 |
20140020081 | Portable Token Device - Disclosed is a portable token device that may be used to assist a user in generating a PIN at one device and to then pass the PIN to another device such that the two devices can securely communicate with one another. The portable token device may include: an interface; and a processor. The processor may execute operations including: determining if a close proximity coupling through the interface to a first device has occurred; transmitting a PIN request to the first device; and obtaining a PIN. Further, the processor may determine if a close proximity coupling through the interface to a second device has occurred. If so, the processor may command transmitting the PIN to the second device. The second device may perform device registration with the first device based upon the received PIN. | 01-16-2014 |
20140101368 | Binding microprocessor to memory chips to prevent re-use of microprocessor - A processor is provided that binds itself to a circuit such that the processor cannot be subsequently reused in other circuits. On a first startup of the processor, a memory segment of an external volatile memory device is read to obtain information prior to initialization of the memory segment. An original/initial identifier may be generated from the information read from the memory segment. The original/initial identifier may then be stored in a non-volatile storage of the processor. On subsequent startups of the processor, it verifies that the processor is still coupled to the same external volatile memory device by using the stored identifier. For instance, on a subsequent startup, the processor again reads the same memory segment of the external memory device and generates a new identifier. If the identifier matches the previously stored identifier, then the processor may continue its operations; otherwise the processor is disabled/halted. | 04-10-2014 |
20140165155 | Management of network devices utilizing an authorization token - Aspects of the invention may relate to an apparatus, system, and method for the management of network devices utilizing an authorization token. In one embodiment, an authorization token received from a service provider may be verified using an authorization credential to determine if the service provider is authorized to perform requested operations with the network device. Further, operation privileges may be enforced that are contained in the authorization token. | 06-12-2014 |
20140357249 | METHODS AND APPARATUS FOR IMPROVING DEVICE FUNCTIONALITY DURING LONG BLOCKING UICC OPERATIONS - Methods and apparatuses are presented herein for improved operation of a Universal Integrated Circuit Card (UICC) of one or more user equipment (UE). For example, an example method of wireless communications is presented, which may include monitoring, by a UE, one or more items received from a UICC of the UE during a UICC operation. In addition, the example method may also include determining that at least one of (a) a number of the one or more items having a first item type exceeds a threshold number, or (b) an elapsed time since the UICC operation started exceeds a threshold time. Moreover, the example method may include providing, based on the determining, a notification to a user interface associated with the UE indicating that the UICC operation is ongoing. | 12-04-2014 |
Patent application number | Description | Published |
20080221154 | HIV-INTEGRASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THEIR USE - Bicyclic hydroxamate compounds represented by the Formula I: | 09-11-2008 |
20090318440 | CARBONYLAMINO PYRROLOPYRAZOLES, POTENT KINASE INHIBITORS - Carbonylamino Pyrrolopyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4. | 12-24-2009 |
20100137283 | INHIBITORS OF THE HIV INTEGRASE ENZYME - The present invention is directed to compounds of formula (I), | 06-03-2010 |
20100222342 | PYRROLOPYRAZOLE, POTENT KINASE INHIBITORS - Pyrrole pyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4. | 09-02-2010 |
20100324074 | Protein Kinase Inhibitors - The present invention is directed to low molecular weight and orally bioavailable 3H-[1,2,3]triazolo[4,5-d]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the tyrosine kinase MET. The invention is also directed to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 12-23-2010 |
20120136014 | DIHYDROFOLATE REDUCTASE INHIBITORS - The present disclosure provides compounds of Formula I: | 05-31-2012 |
20120238751 | TRICYCLIC GYRASE INHIBITORS - Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. | 09-20-2012 |
20120264751 | PYRROLOPYRAZOLES, POTENT KINASE INHIBITORS - Pyrrole pyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4. | 10-18-2012 |
20130079323 | GYRASE INHIBITORS - Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth. Compounds of Formula (I), are disclosed: Formula (I), wherein Y is N or CH; Z is N or CR | 03-28-2013 |
Patent application number | Description | Published |
20110050334 | Integrated Voltage Regulator with Embedded Passive Device(s) - A semiconductor packaging system has a packaging substrate into which inductors and/or capacitors are partially or completely embedded. An active portion of a voltage regulator is mounted on the packaging substrate and supplies regulated voltage to a die also mounted on the packaging substrate. Alternatively, the active portion of the voltage regulator is integrated into the die the voltage regulator supplies voltage to. The voltage regulator cooperates with the inductors and/or capacitors to supply voltage to the die. The inductors may be through vias in the packaging substrate. For additional inductance, through vias in a printed circuit board on which the packaging substrate is mounted may couple to the through vias in the packaging substrate. | 03-03-2011 |
20110215863 | Integrated Voltage Regulator with Embedded Passive Device(s) - A method of supplying voltage to a die mounted on a packaging substrate includes mounting an active portion of a voltage regulator on the packaging substrate. The method also includes coupling the active portion of the voltage regulator to at least one passive component at least partially embedded in the packaging substrate and coupling the die to the at least one passive component. Mounting the active portion of the voltage regulator includes mounting the die on the packaging substrate where the die includes the active portion of the voltage regulator. | 09-08-2011 |
20110234300 | Low Voltage Temperature Sensor and use Thereof for Autonomous Multiprobe Measurement Device - A bandgap sensor which measures temperatures within an integrated circuit is presented. The sensor may include a first transistor having an emitter node coupled in series to a first resistor and a first current source, wherein a PTAT current flows through the first resistor, and a second transistor having a base node coupled to a base node of the first transistor, and a collector node coupled to a collector node of the first transistor, further wherein the first and second transistors are diode connected. The sensor may further include a first operational amplifier providing negative feedback to the first current source, wherein the negative feedback is related to a difference in the base-emitter voltages of the first and second transistors, and a second operational amplifier which couples the base-emitter voltage of the second transistor across a second resistor, wherein a CTAT current flows through the second resistor. | 09-29-2011 |
20110317387 | Integrated Voltage Regulator with Embedded Passive Device(s) for a Stacked IC - A stacked integrated circuit includes a first tier IC and a second tier IC. Active faces of the first tier IC and the second tier IC face each other. An interconnect structure, such as microbumps, couples the first tier IC to the second tier IC. An active portion of a voltage regulator is integrated in the first semiconductor IC and coupled to passive components (for example a capacitor or an inductor) embedded in a packaging substrate on which the stacked IC is mounted. The passive components may be multiple through vias in the packaging substrate providing inductance to the active portion of the voltage regulator. The inductance provided to the active portion of the voltage regulator is increased by coupling the through via in the packaging substrate to through vias in a printed circuit board that the packaging substrate is mounted on. | 12-29-2011 |
20120293972 | Integrated Voltage Regulator Method with Embedded Passive Device(s) - A stacked integrated circuit (IC) device includes a semiconductor IC having an active face, and an interconnect structure. The active face receives a regulated voltage from a voltage regulator (MEG). An active portion of the VREG, which supplies the regulated voltage to the semiconductor IC is coupled to the interconnect structure. A packaging substrate includes one or more inductors including a first set of through vias. The first set of through vias are coupled to the interconnect structure and cooperate with the active portion to provide the regulated voltage for the semiconductor IC. The IC also includes a printed circuit board (PCB) coupled to the packaging substrate. The PCB includes a second set of through vias coupled to the first set of through vias. The IC also includes one or more conducting paths on the PCB. The conducting path(s) couple together at least two through vias of the second set of through vias. | 11-22-2012 |
20130083825 | LOW VOLTAGE TEMPERATURE SENSOR AND USE THEREOF FOR AUTONOMOUS MULTIPROBE MEASUREMENT DEVICE - A bandgap sensor which measures temperatures within an integrated circuit is presented. The sensor may include a first transistor having an emitter node coupled series to a first resistor and a first current source, wherein a PTAT current flows through the first resistor, and a second transistor having a base node coupled to a base node of the first transistor, and a collector node coupled to a collector node of the first transistor, further wherein the first and second transistors are diode connected. The sensor may further include a first operational amplifier providing negative feedback to the first current source, wherein the negative feedback is related to a difference in the base-emitter voltages of the first and second transistors, and a second operational amplifier which couples the base-emitter voltage of the second transistor across a second resistor, wherein a CTAT current flows through the second resistor. | 04-04-2013 |
20130099764 | SYSTEM AND METHOD TO REGULATE VOLTAGE - A system and method to regulate voltage is disclosed. In a particular embodiment, a voltage regulator includes an error amplifier, a voltage buffer responsive to the error amplifier, and a first transistor responsive to the voltage buffer and coupled to a voltage supply source. A second transistor is coupled to the voltage supply source and further coupled to an output node. A third transistor is coupled to the first transistor and has a gate coupled to a capacitor. The capacitor is coupled to a node between the error amplifier and the voltage buffer. | 04-25-2013 |
Patent application number | Description | Published |
20090074828 | POLY(AMINO ACID) TARGETING MOIETIES - The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries. | 03-19-2009 |
20100196482 | POLYMER-ENCAPSULATED REVERSE MICELLES - A method for encapsulating nucleic acids, particularly siRNAs, shRNAs, microRNAs, gene therapy plasmids, and other oligonucleotides in biodegradable polymers is disclosed, whereby the nucleic acids are formulated into reverse micelles composed of non-toxic and/or naturally-occurring lipids prior to nanoparticle formation by nanoprecipitation. This method can be coupled to other techniques that improve intracellular drug targeting, ultimately enhancing intracellular delivery of the aforementioned nucleic acids. | 08-05-2010 |
20100203142 | AMPHIPHILIC COMPOUND ASSISTED NANOPARTICLES FOR TARGETED DELIVERY - The present invention generally relates to nanoparticles with an amphiphilic component. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries. | 08-12-2010 |
20110027172 | DRUG DELIVERY SYSTEM FOR PHARMACEUTICALS AND RADIATION - The present invention provides a drug delivery system for delivery of an agent and a radiopharmaceutical agent. The drug delivery system may specifically target an organ, tissue, cells, extracellular matrix, or intracellular compartment. Typically, the drug delivery system is a particle. Pharmaceutical compositions comprising the inventive particles are also provided. The present invention provides methods of preparing and using the inventive particles and pharmaceutical compositions. The inventive particles are useful in treating and diagnosing a variety of diseases including cancer. The inventive particles are also useful in tracking particles in vivo. | 02-03-2011 |
20120156135 | PARTICLES WITH MULTIPLE FUNCTIONALIZED SURFACE DOMAINS - This disclosure relates to particles (e.g., nanoparticles and microparticles) that display multiple functionalized surface domains in a controlled mosaic pattern. The disclosure also provides simple methods to create various particles that have multiple functionalized surface domains while allowing the use of a wide variety of diverse core structures. The multiple functionalized domains provide controllable particle binding and orientation, and controlled and sustained drug release profiles. | 06-21-2012 |
20130028962 | Triggered Cargo Release from Nanoparticle Stabilized Liposomes - Control of the fusion activity of liposomes by adsorbing biocompatible nanoparticles to the outer surface of phospholipid liposomes is disclosed. The biocompatible nanoparticles effectively prevent liposomes from fusing with one another. Release of cargo from the liposome is accomplished via trigger mechanisms that include pH triggers, pore forming toxing triggers and photosensitive triggers. Dermal drug delivery to treat a variety of skin diseases such as acne vulgaris and staph infections is contemplated. | 01-31-2013 |
20130122056 | Ratiometric Combinatorial Drug Delivery - The present teachings include ratiometric combinatorial drug delivery including nanoparticles, multi-drug conjugates, pharmaceutical compositions, methods of producing such compositions and methods of using such compositions, including in the treatment of diseases and conditions using drug combinations. | 05-16-2013 |
20130236533 | Vaccine Nanotechnology - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof. | 09-12-2013 |
20130287857 | Vaccine Nanotechnology - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof. | 10-31-2013 |
20130337066 | Membrane Encapsulated Nanoparticles and Method of Use - Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided. | 12-19-2013 |
20140314865 | Vaccine Nanotechnology - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof. | 10-23-2014 |
Patent application number | Description | Published |
20110266635 | Native Devices Having Improved Device Characteristics and Methods for Fabrication - A method for fabricating a native device is presented. The method includes forming a gate structure over a substrate starting at an outer edge of an inner marker region, where the gate structure extends in a longitudinal direction, and performing MDD implants, where each implant is performed using a different orientation with respect to the gate structure, performing pocket implants, where each implant is performed using a different orientation with respect to the gate structure, and concentrations of the pocket implants vary based upon the orientations. A transistor fabricated as a native device, is presented, which includes an inner marker region, an active outer region which surrounds the inner marker region, a gate structure coupled to the inner marker region, and first and second source/drain implants located within the active outer region and interposed between the first source/drain implant and the second source/drain implant. | 11-03-2011 |
20140035067 | NATIVE DEVICES HAVING IMPROVED DEVICE CHARACTERISTICS AND METHODS FOR FABRICATION - A method for fabricating a native device is presented. The method includes forming a gate structure over a substrate starting at an outer edge of an inner marker region, where the gate structure extends in a longitudinal direction, and performing MDD implants, where each implant is performed using a different orientation with respect to the gate structure, performing pocket implants, where each implant is performed using a different orientation with respect to the gate structure, and concentrations of the pocket implants vary based upon the orientations. A transistor fabricated as a native device, is presented, which includes an inner marker region, an active outer region which surrounds the inner marker region, a gate structure coupled to the inner marker region, and first and second source/drain implants located within the active outer region and interposed between the first source/drain implant and the second source/drain implant. | 02-06-2014 |
20150048465 | SMALL FORM FACTOR MAGNETIC SHIELD FOR MAGNETORESTRICTIVE RANDOM ACCESS MEMORY (MRAM) - Some implementations provide a die that includes a magnetoresistive random access memory (MRAM) cell array that includes several MRAM cells. The die also includes a first ferromagnetic layer positioned above the MRAM cell array, a second ferromagnetic layer positioned below the MRAM cell array, and several vias positioned around at least one MRAM cell. The via comprising a ferromagnetic material. In some implementations, the first ferromagnetic layer, the second ferromagnetic layer and the several vias define a magnetic shield for the MRAM cell array. The MRAM cell may include a magnetic tunnel junction (MTJ). In some implementations, the several vias traverse at least a metal layer and a dielectric layer of the die. In some implementations, the vias are through substrate vias. In some implementations, the ferromagnetic material has high permeability and high B saturation. | 02-19-2015 |
Patent application number | Description | Published |
20090201838 | DYNAMIC ADJUSTMENT OF DOWNLINK/UPLINK ALLOCATION RATIO IN TDD WIRELESS SYSTEMS - Techniques, apparatuses, and systems for dynamically changing downlink and uplink allocations can include operating a base station under time division duplexing to communicate with one or more mobile devices using a frame structure, adjusting a downlink-uplink ratio to change an allocation between uplink and downlink data capacities in the frame structure, determining a mute interval based on the adjusted downlink-uplink ratio, generating mute information based on the mute interval to identify the one or more areas of the frame structure effected by the allocation change, and transmitting the mute information to the one or more mobile devices. | 08-13-2009 |
20090207725 | METHOD AND SYSTEM FOR JOINT ENCODING MULTIPLE INDEPENDENT INFORMATION MESSAGES - A method and system for joint encoding multiple independent information messages are disclosed. In one embodiment, a system includes an encoder configured to encode each of the independent information messages to produce respective encoded bits, and a first multiplexer configured to multiplex each of the independent information messages. A joint block encoder encodes the multiplexed independent information messages to produce encoded common parity bits shared by all independent information messages, and a second multiplexer multiplexes the respective encoded bits from all independent channel encoders and the encoded common parity bits from the joint block encoder to produce the final output. | 08-20-2009 |
20090249153 | DYNAMIC ADJUSTMENT AND SIGNALING OF DOWNLINK/UPLINK ALLOCATION RATIO IN LTE/TDD SYSTEMS - A method for dynamic adjustment of downlink/uplink resource allocation ratio in a long-term evolution (LTE) time division duplex (TDD) system is disclosed. The method includes replacing at least one of an uplink subframe and a downlink subframe with a mute subframe in a subframe pattern, indicating a first downlink/uplink resource allocation ratio. Thereafter, the mute subframe is replaced with either the uplink subframe or the downlink subframe to form another subframe pattern. The subframe pattern including the mute subframe is obtained from a lookup table, such that the replacing the mute subframe results in the other pattern. A data transmission in accordance with the other subframe pattern, indicating a second downlink/uplink resource allocation ratio, may be scheduled. Hybrid Automatic Repeat-request (HARQ) processing may be implemented after the at least one of the uplink subframe and the downlink subframe is replaced with the mute subframe in the first subframe pattern. | 10-01-2009 |
20100029278 | USING IDENTIFICATION SEQUENCES IN WIRELESS COMMUNICATION SYSTEMS - Techniques, apparatuses, and systems for using identification sequences in a wireless communication system can include receiving information indicative of a pilot code detected by a wireless device, the pilot code being shared by multiple Femto Access Points (FAPs) that each provide wireless service in at least a portion of the coverage area; receiving information indicative of an identification sequence detected by the wireless device that is associated with the pilot code, using the information indicative of the identification sequence to identify one of the FAPs that share the pilot code; and performing a hand-off of the call to the identified FAP to continue to provide wireless service for the call via the identified FAP. | 02-04-2010 |
20100197309 | VIRTUAL GROUPS FOR FEMTO-CELL HAND-IN - Techniques, apparatuses, and systems for handling femto-cell hand-in requests can include operating a macro-cell base station to provide wireless service to wireless devices in a geographical coverage area; receiving, from a wireless device, a message indicative of the wireless device's reception of a base station radio signal, the message including a base station identifier; controlling multiple femto-cell base stations that are assigned to the base station identifier to communicate with the wireless device and to report a reception of a radio signal from the wireless device; and transferring the wireless device from the macro-cell base station to a femto-cell base station of the multiple femto-cell base stations that reports a reception of the radio signal from the wireless device. The multiple femto-cell base stations can provide wireless service in different nonadjacent portions of the geographical coverage area. | 08-05-2010 |
20120294206 | DYNAMIC ADJUSTMENT OF DOWNLINK/UPLINK ALLOCATION RATIO IN TDD WIRELESS SYSTEMS - Techniques, apparatuses, and systems for dynamically changing downlink and uplink allocations can include operating a base station under time division duplexing to communicate with one or more mobile devices using a frame structure, adjusting a downlink-uplink ratio to change an allocation between uplink and downlink data capacities in the frame structure, determining a mute interval based on the adjusted downlink-uplink ratio, generating mute information based on the mute interval to identify the one or more areas of the frame structure effected by the allocation change, and transmitting the mute information to the one or more mobile devices. | 11-22-2012 |
Patent application number | Description | Published |
20090012786 | Adaptive Noise Cancellation - Speech-free noise estimation by cancellation of speech content from an audio input where the speech content is estimated by noise suppression. Adaptive noise cancellation with primary and noise-reference inputs and an adaptive noise cancellation filter from estimating primary noise from noise-reference input. Speech Suppressor (Noise Estimation) applied to noise-reference input provides speech-free noise estimates for noise cancellation in the primary input. | 01-08-2009 |
20090034752 | CONSTRAINTED SWITCHED ADAPTIVE BEAMFORMING - An audio device, comprising a microphone array, a constrained switched adaptive beamformer with input coupled to said microphone array, said beamformer including (i) a first stage speech adaptive beamformer with first adaptive filters having a first adaptive step size, and (ii) a second stage noise adaptive beamformer with second adaptive filters having a second adaptive step size, and a single channel speech enhancer with input coupled to an output of said constrained switched adaptive beamformer. | 02-05-2009 |
20110099007 | NOISE ESTIMATION USING AN ADAPTIVE SMOOTHING FACTOR BASED ON A TEAGER ENERGY RATIO IN A MULTI-CHANNEL NOISE SUPPRESSION SYSTEM - Techniques are described herein that provide multi-channel noise suppression based on a Teager energy ratio. A Teager energy ratio is a ratio of an average Teager energy operator (TEO) energy of a first signal to an average TEO energy of a second signal. The average TEO energy of a signal is defined by the equation: | 04-28-2011 |
20110099010 | MULTI-CHANNEL NOISE SUPPRESSION SYSTEM - Techniques are described herein that provide multi-channel noise suppression based on a Teager energy ratio. A Teager energy ratio is a ratio of an average Teager energy operator (TEO) energy of a first signal to an average TEO energy of a second signal. The average TEO energy of a signal is defined by the equation: | 04-28-2011 |
20120121100 | Method and Apparatus For Wind Noise Detection and Suppression Using Multiple Microphones - Unlike sound based pressure waves that go everywhere, air turbulence caused by wind is usually a fairly local event. Therefore, in a system that utilizes two or more spatially separated microphones to pick up sound signals (e.g., speech), wind noise picked up by one of the microphones often will not be picked up (or at least not to the same extent) by the other microphone(s). Embodiments of methods and apparatuses that utilize this tact and others to effectively detect and suppress wind noise using multiple microphones that are spatially separated are described. | 05-17-2012 |
20120123771 | Method and Apparatus For Wind Noise Detection and Suppression Using Multiple Microphones - Unlike sound based pressure waves that go everywhere, air turbulence caused by wind is usually a fairly local event. Therefore, in a system that utilizes two or more spatially separated microphones to pick up sound signals (e.g., speech), wind noise picked up by one of the microphones often will not be picked up (or at least not to the same extent) by the other microphone(s). Embodiments of methods and apparatuses that utilize this fact and others to effectively detect and suppress wind noise using multiple microphones that are spatially separated are described. | 05-17-2012 |
20120123772 | System and Method for Multi-Channel Noise Suppression Based on Closed-Form Solutions and Estimation of Time-Varying Complex Statistics - Multi-channel noise suppression systems and methods are described that omit the traditional delay-and-sum fixed beamformer in devices that include a primary speech microphone and at least one noise reference microphone with the desired speech being in the near-field of the device. The multi-channel noise suppression systems and methods use a blocking matrix (BM) to remove desired speech in the input speech signal received by the noise reference microphone to get a “cleaner” background noise component. Then, an adaptive noise canceler (ANC) is used to remove the background noise in the input speech signal received by the primary speech microphone based on the “cleaner” background noise component to achieve noise suppression. The filters implemented by the BM and ANC are derived using closed-form solutions that require calculation of time-varying statistics of complex frequency domain signals in the noise suppression system. | 05-17-2012 |
20120123773 | System and Method for Multi-Channel Noise Suppression - Described herein are multi-channel noise suppression systems and methods that are configured to detect and suppress wind and background noise using at least two spatially separated microphones: at least one primary speech microphone and at least one noise reference microphone. The multi-channel noise suppression systems and methods are configured, in at least one example, to first detect and suppress wind noise in the input speech signal picked up by the primary speech microphone and, potentially, the input speech signal picked up by the noise reference microphone. Following wind noise detection and suppression, the multi-channel noise suppression systems and methods are configured to perform further noise suppression in two stages: a first linear processing stage that includes a blocking matrix and an adaptive noise canceler, followed by a second non-linear processing stage. | 05-17-2012 |
20120183154 | USE OF SENSORS FOR NOISE SUPPRESSION IN A MOBILE COMMUNICATION DEVICE - Techniques are described herein that use sensors (e.g., microphones) for noise reduction in a mobile communication device. For example, one technique enables a first sensor that is initially configured to be a speech sensor to be used as a noise reference sensor. This technique also enables a second sensor that is initially configured to be a noise reference sensor to be used as a speech sensor. Another technique enables a primary sensor and/or a secondary sensor in a handset of a mobile communication device to be used as a speech sensor while a sensor in a headset of the mobile communication device is used as a noise reference sensor, or vice versa. In yet another technique, a secondary sensor in a mobile communication device is configured to be a directional sensor. | 07-19-2012 |
20120185246 | NOISE SUPPRESSION USING MULTIPLE SENSORS OF A COMMUNICATION DEVICE - Techniques are described herein that suppress noise using multiple sensors (e.g., microphones) of a communication device. Noise modeling (e.g., estimation of noise basis vectors and noise weighting vectors) is performed with respect to a noise signal during operation of a communication device to provide a noise model. The noise model includes noise basis vectors and noise coefficients that represent noise provided by audio sources other than a user of the communication device. Speech modeling (e.g., estimation of speech basis vectors and speech weighting) is performed to provide a speech model. The speech model includes speech basis vectors and speech coefficients that represent speech of the user. A noisy speech signal is processed using the noise basis vectors, the noise coefficients, the speech basis vectors, and the speech coefficients to provide a clean speech signal. | 07-19-2012 |
20130117014 | MULTIPLE MICROPHONE BASED LOW COMPLEXITY PITCH DETECTOR - Disclosed are various embodiments of multiple microphone based pitch detection. In one embodiment, a method includes obtaining a primary signal and a secondary signal associated with multiple microphones. A pitch value is determined based at least in part upon a level difference between the primary and secondary signals. In another embodiment, a system includes a plurality of microphones configured to provide a primary signal and a secondary signal. A level difference detector is configured to determine a level difference between the primary and secondary signals and a pitch identifier is configured to clip the primary and secondary signals based at least in part upon the level difference. In another embodiment, a method determines the presence of voice activity based upon a pitch prediction gain variation that is determined based at least in part upon a pitch lag. | 05-09-2013 |
Patent application number | Description | Published |
20110245948 | Method And Circuit To Generate Race Condition Test Data At Multiple Supply Voltages - A method and circuit for characterizing a process variation of a semiconductor die is disclosed. In a particular embodiment, the method includes operating a circuit at multiple supply voltage levels to generate race condition testing data. The circuit is disposed on at least one die of a wafer and includes at least one racing path circuit having at least two paths. The method further includes collecting the race condition testing data and evaluating the collected race condition testing data. The race condition testing data is correlated to a process variation of the at least one die. | 10-06-2011 |
20120210284 | Method and Apparatus for Characterizing and Reducing Proximity Effect on Cell Electrical Characteristics - Circuit elements are characterized for effects of proximity context on electrical characteristic. Based on the characterization, proximity context cell models, and corresponding modeled electrical characteristic values are obtained. Logic cells are characterized and modeled according to the proximity context cell models. Optionally the electrical characteristic can be time delay, leakage, dynamic power, or coupling noise among other parameters. | 08-16-2012 |
20130007681 | YIELD BASED FLOP HOLD TIME AND SETUP TIME DEFINITION - Systems and method for defining a timing parameter for a circuit element based on process variation, including, determining a point of failure parameter associated with the timing parameter, the point of failure parameter correlated with a specific value of the process variation. A standard deviation associated with the point of failure parameter is determined. The process variation per the standard deviation is calculated and the timing parameter for the circuit element is defined as a function of the failure parameter, the standard deviation, and the process variation per the standard deviation. A margin factor, which varies with the standard deviation, is optionally applied to the timing parameter. The timing parameter may be one of a setup time or hold time. | 01-03-2013 |
20140246753 | HIGH QUALITY FACTOR INDUCTOR IMPLEMENTED IN WAFER LEVEL PACKAGING (WLP) - Some novel features pertain to a first example provides a semiconductor device that includes a printed circuit board (PCB), asset of solder balls and a die. The PCB includes a first metal layer. The set of solder balls is coupled to the PCB. The die is coupled to the PCB through the set of solder balls. The die includes a second metal layer and a third metal layer. The first metal layer of the PCB, the set of solder balls, the second and third metal layers of the die are configured to operate as an inductor in the semiconductor device. In some implementations, the die further includes a passivation layer. The passivation layer is positioned between the second metal layer and the third metal layer. In some implementations, the second metal layer is positioned between the passivation layer and the set of solder balls. | 09-04-2014 |
20140252544 | DC/ AC DUAL FUNCTION POWER DELIVERY NETWORK (PDN) DECOUPLING CAPACITOR - Some implementations provide a semiconductor device that includes a first substrate, a die coupled to the first substrate, and a set of solder balls coupled to the first substrate. The set of solder balls is configured to provide an electrical connection between the die and a second substrate. The semiconductor device also includes at least one decoupling capacitor coupled to the die through the first substrate. The at least one decoupling capacitor is configured to provide an electrical connection between the die and the second substrate. The at least one decoupling capacitor is coupled to the first substrate such that the at least one decoupling capacitor is positioned between the first substrate and the second substrate. In some implementations, the second substrate is a printed circuit board (PCB). In some implementations, the first substrate is a first package substrate, and the second substrate is a second package substrate. | 09-11-2014 |
20140319652 | HIGH QUALITY FACTOR FILTER IMPLEMENTED IN WAFER LEVEL PACKAGING (WLP) INTEGRATED DEVICE - Some implementations provide an integrated device that includes a capacitor and an inductor. The inductor is electrically coupled to the capacitor. The inductor and the capacitor are configured to operate as a filter for an electrical signal in the integrated device. The inductor includes a first metal layer of a printed circuit board (PCB), a set of solder balls coupled to the PCB, and a second metal layer in a die. In some implementations, the capacitor is located in the die. In some implementations, the capacitor is a surface mounted passive device on the PCB. In some implementations, the first metal layer is a trace on the PCB. In some implementations, the inductor includes a third metal layer in the die. In some implementations, the second metal layer is an under bump metallization (UBM) layer of the die, and the third metal is a redistribution layer of the die. | 10-30-2014 |
20150048480 | INTEGRATED PASSIVE DEVICE (IPD) ON SUBTRATE - Some novel features pertain to a semiconductor device that includes a substrate, a first cavity that traverses the substrate. The first cavity is configured to be occupied by a interconnect material (e.g., solder ball). The substrate also includes a first metal layer coupled to a first side wall of the first cavity. The substrate further includes a first integrated passive device (IPD) on a first surface of the substrate, the first IPD coupled to the first metal layer. In some implementations, the substrate is a glass substrate. In some implementations, the first IPD is one of at least a capacitor, an inductor and/or a resistor. In some implementations, the semiconductor device further includes a second integrated passive device (IPD) on a second surface of the substrate. The second IPD is coupled to the first metal layer. | 02-19-2015 |
Patent application number | Description | Published |
20110053893 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS - The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine. | 03-03-2011 |
20110081365 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS - The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X | 04-07-2011 |
20120177681 | Formulation of immunopotentiators - Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminium salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention time, and/or immunostimulatory effect. Immunopotentiators are modified to introduce a moiety, such as a phosphonate group, which can mediate adsorption. These modified compounds can retain or improve their in vivo immunological activity even when delivered in an adsorbed form. | 07-12-2012 |
20130253002 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS - The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X | 09-26-2013 |
20130274465 | ADSORPTION OF IMMUNOPOTENTIATORS TO INSOLUBLE METAL SALTS - Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminium salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention time, and/or immunostimulatory effect. Immunopotentiators are modified to introduce a moiety, such as a phosphonate group, which can mediate adsorption. These modified compounds can retain or improve their in vivo immunological activity even when delivered in an adsorbed form. | 10-17-2013 |
Patent application number | Description | Published |
20120113241 | FINGERTIP TRACKING FOR TOUCHLESS USER INTERFACE - In general, this disclosure describes techniques for providing a gesture-based user interface. For example, according to some aspects of the disclosure, a user interface generally includes a camera and a computing device that identifies and tracks the motion of one or more fingertips of a user. In some examples, the user interface is configured to identify predefined gestures (e.g., patterns of motion) associated with certain motions of the user's fingertips. In another example, the user interface is configured to identify hand postures (e.g., patterns of showing up of fingertips). Accordingly, the user can interact with the computing device by performing the gestures. | 05-10-2012 |
20120139906 | HYBRID REALITY FOR 3D HUMAN-MACHINE INTERFACE - A three dimensional (3D) mixed reality system combines a real 3D image or video, captured by a 3D camera for example, with a virtual 3D image rendered by a computer or other machine to render a 3D mixed-reality image or video. A 3D camera can acquire two separate images (a left and a right) of a common scene, and superimpose the two separate images to create a real image with a 3D depth effect. The 3D mixed-reality system can determine a distance to a zero disparity plane for the real 3D image, determine one or more parameters for a projection matrix based on the distance to the zero disparity plane, render a virtual 3D object based on the projection matrix, combine the real image and the virtual 3D object to generate a mixed-reality 3D image. | 06-07-2012 |
20120140038 | ZERO DISPARITY PLANE FOR FEEDBACK-BASED THREE-DIMENSIONAL VIDEO - The techniques of this disclosure are directed to the feedback-based stereoscopic display of three-dimensional images, such as may be used for video telephony (VT) and human-machine interface (HMI) application. According to one example, a region of interest (ROI) of stereoscopically captured images may be automatically determined based on determining disparity for at least one pixel of the captured images are described herein. According to another example, a zero disparity plane (ZDP) for the presentation of a 3D representation of stereoscopically captured images may be determined based on an identified ROI. According to this example, the ROI may be automatically identified, or identified based on receipt of user input identifying the ROI. | 06-07-2012 |
20120235999 | STEREOSCOPIC CONVERSION FOR SHADER BASED GRAPHICS CONTENT - The example techniques of this disclosure are directed to generating a stereoscopic view from an application designed to generate a mono view. For example, the techniques may modify source code of a vertex shader to cause the modified vertex shader, when executed, to generate graphics content for the images of the stereoscopic view. As another example, the techniques may modify a command that defines a viewport for the mono view to commands that define the viewports for the images of the stereoscopic view. | 09-20-2012 |
20120236002 | 3D TO STEREOSCOPIC 3D CONVERSION - This disclosure describes techniques for modifying application program interface (API) calls in a manner that can cause a device to render native three dimensional (3D) graphics content in stereoscopic 3D. The techniques of this disclosure can be implemented in a manner where API calls themselves are modified, but the API itself and the GPU hardware are not modified. The techniques of the present disclosure include using the same viewing frustum defined by the original content to generate a left-eye image and a right-eye image and shifting the viewport offset of the left-eye image and the right-eye image. | 09-20-2012 |
20120268568 | METHOD AND APPARATUS OF REDUCING VISUAL VIBRATION OF A MOBILE ELECTRONIC DISPLAY - A mobile computing device comprising one or more sensors and an electronic display is disclosed herein. The one or more sensors are adapted to determine a distance between the mobile computing device and a mobile computing device user, and are also adapted to determine a position of the mobile computing device relative to the mobile computing device user. The electronic display is adapted to modify visual content on the electronic display relative to a change in at least one of, the distance between the mobile computing device and a mobile computing device user, and the position of the mobile computing device relative to the mobile computing device user. | 10-25-2012 |
20120321139 | CONTENT-ADAPTIVE SYSTEMS, METHODS AND APPARATUS FOR DETERMINING OPTICAL FLOW - Embodiments include methods and systems which determine pixel displacement between frames based on a respective weighting-value for each pixel or a group of pixels. The weighting-values provide an indication as to which pixels are more pertinent to optical flow computations. Computational resources and effort can be focused on pixels with higher weights, which are generally more pertinent to optical flow determinations. | 12-20-2012 |
20140029807 | CONTENT-ADAPTIVE PIXEL PROCESSING SYSTEMS, METHODS AND APPARATUS - Embodiments include methods and systems for context-adaptive pixel processing based, in part, on a respective weighting-value for each pixel or a group of pixels. The weighting-values provide an indication as to which pixels are more pertinent to pixel processing computations. Computational resources and effort can be focused on pixels with higher weights, which are generally more pertinent for certain pixel processing determinations. | 01-30-2014 |
20140192053 | STEREOSCOPIC CONVERSION WITH VIEWING ORIENTATION FOR SHADER BASED GRAPHICS CONTENT - The example techniques of this disclosure are directed to generating a stereoscopic view from an application designed to generate a mono view. For example, the techniques may modify instructions for a vertex shader based on a viewing angle. When the modified vertex shader is executed, the modified vertex shader may generate coordinates for vertices for a stereoscopic view based on the viewing angle. | 07-10-2014 |
20140334740 | CONTENT-ADAPTIVE PIXEL PROCESSING SYSTEMS, METHODS AND APPARATUS - Embodiments include methods and systems for context-adaptive pixel processing based, in part, on a respective weighting-value for each pixel or a group of pixels. The weighting-values provide an indication as to which pixels are more pertinent to pixel processing computations. Computational resources and effort can be focused on pixels with higher weights, which are generally more pertinent for certain pixel processing determinations. | 11-13-2014 |
Patent application number | Description | Published |
20110250642 | Method for Displaying Antibodies - There is disclosed vector designs, constructs and approaches to construct antibody libraries that display antibodies, such as full-length immunoglobulins, single chain antibody (SCA) scFv, or Fab on the host cell surface. There is also disclosed screening approaches to isolate desired antibody binders from above mentioned antibody libraries for selective antibody targets. | 10-13-2011 |
20130323248 | Antigen Binding Proteins that Bind DLL-4 - There is disclosed compositions and methods relating to or derived from anti-DLL-4 antibodies. More specifically, there is disclosed fully human antibodies that bind DLL-4, DLL-4-binding fragments and derivatives of such antibodies, and DLL-4-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having DLL-4 related disorders or conditions, including various inflammatory disorders and various cancers. | 12-05-2013 |
20140120092 | Antigen Binding Proteins that Bind ErbB3 - There is disclosed compositions and methods relating to or derived from anti-ErbB3 antibodies. More specifically, there is disclosed fully human antibodies that bind ErbB3, ErbB3-binding fragments and derivatives of such antibodies, and ErbB3-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having ErbB3 related disorders or conditions, including various inflammatory disorders and various cancers. | 05-01-2014 |