Zaleski, US
Christopher Zaleski, Guilderland, NY US
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20080281529 | GENOMIC DATA PROCESSING UTILIZING CORRELATION ANALYSIS OF NUCLEOTIDE LOCI OF MULTIPLE DATA SETS - Processing of genomic data is facilitated utilizing correlation analysis of mapped data sets, each data set including genomic data mapped and ordered relative to a genomic coordinate system. Correlation analysis identifies at a nucleotide level nucleotide positions wherein at least one nucleotide locus of each data set correlate. The analysis includes for each data set, selecting a nucleotide locus thereof closest to one end of the coordinate system, comparing the selected nucleotide loci for correlation, and if so, outputting results of the comparing, and updating the selected nucleotide loci by identifying the data set having a next nucleotide locus closest to the one end of the coordinate system, and inserting that next locus into the group of selected loci, and repeating the comparing for the newly selected loci. The process is repeated until nucleotide loci of the mapped data sets are compared and results of the comparison are output. | 11-13-2008 |
20080281530 | GENOMIC DATA PROCESSING UTILIZING CORRELATION ANALYSIS OF NUCLEOTIDE LOCI - Processing of genomic data is provided utilizing correlation analysis of first and second nucleotide loci employing a selected comparison type and value. The comparison type is either intersection or proximity type, and the comparison value is either a number (n) of nucleotide positions, wherein n≧1, or a percent number (pn) of nucleotide positions, wherein pn≧0, to be employed in comparing the loci. When intersection type is selected, correlation is defined by the loci overlapping with at least the number (n) of nucleotide positions in common, or by the loci overlapping with at least the percent number (pn) of nucleotide positions in common relative to a smaller one of the first and second loci, or when proximity type is selected, correlation is defined by the first and second loci being within at least the number (n) of nucleotide positions. | 11-13-2008 |
20080281818 | SEGMENTED STORAGE AND RETRIEVAL OF NUCLEOTIDE SEQUENCE INFORMATION - Processing of genomic data is facilitated by providing a storage device with a database having a segmented sequence table. The table has a plurality of data subsets of common nucleotide sequence size n, wherein≧2, and each data subset of common nucleotide sequence n is separately indexed within the table. A database manager associated with the database retrieves a selected nucleotide sequence locus from the table. The selected nucleotide sequence locus is sized differently from the common nucleotide sequence size n, and the retrieving includes identifying each data subset of the segmented sequence table containing at least a portion of the selected nucleotide sequence locus, and retrieving the identified data subsets. The database manager processes the retrieved, identified data subsets to remove genomic data mapped to the nucleotide positions outside the selected nucleotide sequence locus, and outputs the selected nucleotide sequence locus. | 11-13-2008 |
20080281819 | NON-RANDOM CONTROL DATA SET GENERATION FOR FACILITATING GENOMIC DATA PROCESSING - Processing of genomic data is facilitated by providing a control data set generation system wherein a control generator tool or process creates matched data sets for facilitating informatics analysis. These matched data sets may include genomic loci or genomic sequences, or both. The data is taken from a database of actual genomic data, including sequence and annotation data, as opposed to ad-hoc generation, sequence scrambling or the like. This produces biologically relevant and accurate results which allow for stronger controls. The controls are matched against a user-provided data set via a number of parameters. | 11-13-2008 |
Christopher Zaleski, Huntington, NY US
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20120252876 | TRANS-ACTING RNA SWITCHES - Disclosed are RNA constructs which function to activate or inactivate a biological process, e.g., may be designed for attachment to a polypeptide coding region. Such RNA constructs modulate translation of a polypeptide from the coding region in response to the presence of a target polynucleotide in an expression environment. Such RNA constructs include a weakened stem-loop structure which, when bound to the target polynucleotide, assumes stem-loop secondary structure and associates with an RNA binding protein. Association with the RNA binding protein modulates translation of the polypeptide coding region. Such RNA constructs also have three-way junction joining regions 3′ and 5′ of the stem-loop structure. | 10-04-2012 |
20150045414 | TRANS-ACTING RNA SWITCHES - Disclosed are RNA constructs which function to activate or inactivate a biological process, e.g., may be designed for attachment to a polypeptide coding region. Such RNA constructs modulate translation of a polypeptide from the coding region in response to the presence of a target polynucleotide in an expression environment. Such RNA constructs include a weakened stem-loop structure which, when bound to the target polynucleotide, assumes stem-loop secondary structure and associates with an RNA binding protein. Association with the RNA binding protein modulates translation of the polypeptide coding region. Such RNA constructs also have three-way junction joining regions 3′ and 5′ of the stem-loop structure. | 02-12-2015 |
Edmund Joseph Zaleski, Dalton, OH US
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20120017577 | HYDRAULIC SOFT START SYSTEM - A hydraulic soft-start system includes a first flow valve in fluid communication with a pressure source and an inlet of a motor. A first restricting orifice is disposed between the first valve and the inlet. A second flow valve is in fluid communication with the first valve and the inlet. A pilot for actuating the second valve is in fluid communication with the inlet. A second restricting orifice is disposed between the pilot and the inlet. Upon actuation of the first valve, a first flow is passed from the pressure source via the first orifice to the inlet, placing the motor in a partially-actuated state. The second valve being actuated after a threshold pressure of the pilot is reached allowing a second flow to pass from the pressure source to the inlet. The second flow being higher than the first flow, thereby placing the motor in a fully-actuated state. | 01-26-2012 |
20140041373 | HYDRAULIC SOFT START SYSTEM - A hydraulic soft-start system includes a first flow restricting orifice and a flow control valve both being in fluid communication with a pressure source and an inlet of a motor. Also provided is a second flow restricting orifice disposed between a pilot for actuating the flow control valve and the inlet of the motor. A first flow is passed from the pressure source via the first orifice to an inlet of the motor, placing the motor in a partially-actuated state. The flow control valve is actuated after a threshold pressure of the pilot is reached allowing a second flow to pass from the pressure source to the motor inlet. The second flow is higher than the first flow, thereby placing the motor in a fully-actuated state. | 02-13-2014 |
20150128584 | HYDRAULIC SOFT START SYSTEM - A hydraulic soft-start system includes a flow control valve which is in fluid communication with a pressure source and an inlet of a motor. The system includes a first flow restricting orifice and a second flow restricting orifice disposed between a pilot for actuating the flow control valve and the inlet of the motor. A first flow is passed from the pressure source via the first orifice to an inlet of the motor, placing the motor in a partially-actuated state. The flow control valve is actuated after a threshold pressure of the pilot is reached allowing a second flow to pass from the pressure source to the motor inlet. The second flow is higher than the first flow, thereby placing the motor in a fully-actuated state. | 05-14-2015 |
Edward Zaleski, Santa Ana, CA US
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20080269642 | ANGLE INDICATOR FOR CAPSULAR BAG SIZE MEASUREMENT - Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. After the natural crystalline lens has been surgically removed, a flexible ring may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag. The ring is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring has a central component that changes shape as the ring is compressed. The shape change is generally correlated to the size of the capsular bag and may be measured visually or with a camera through the cornea, the measurement being generally independent of corneal magnification. | 10-30-2008 |
20110292336 | ANGLE INDICATOR FOR OCULAR MEASUREMENTS - Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. A flexible ring or ring portion may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag, for example, after extraction of a natural lens from the capsular bag. The ring or ring portion is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring or ring portion includes a central component that changes shape and/or angle as the ring or ring portion is compressed. The shape change is generally correlated to the size of the capsular bag and may be visually measured through the cornea, the measurement being generally independent of corneal magnification. The measurement may be used to determine or calculate information about the capsular bag such as its size, elasticity, accommodative range, and so forth. | 12-01-2011 |
Edward R. Zaleski, Santa Ana, CA US
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20090069814 | Medical Device for Rapid and Accurate Entry through Soft Tissue and Bone - A device for entering soft tissue and bone of a body, including a spike with a grommet thereabout. | 03-12-2009 |
20100036391 | METHOD FOR RAPID AND ACCURATE ENTRY THROUGH SOFT TISSUE AND BONE - A method for entering soft tissue and bone of a body, the method includes sterilizing a scalp, injecting a spike, with a grommet thereabout, through a calvaria, and removing the spike and leaving the grommet inserted in the calvaria, the grommet providing intracranial access. | 02-11-2010 |
Erin Zaleski, North Brunswick, NJ US
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20140004068 | TOPICAL APPLICATION OF 1-HYDROXYL 3,5-BIS(4'HYDROXYL STYRYL)BENZENE | 01-02-2014 |
20150257992 | TOPICAL APPLICATION OF 1-HYDROXYL 3,5-BIS(4'HYDROXYL STYRYL)BENZENE - The present invention relates to compositions comprising 1-hydroxyl 3,5-bis(4′hydroxyl styryl)benzene or a cosmetically acceptable salt thereof, and methods of treating human skin and signs of skin aging using said compositions. | 09-17-2015 |
Garry Zaleski, Eastlake, OH US
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20080236856 | DAMPER ASSEMBLY STAKING SYSTEM - A damper assembly staking system that provides for staking damper weights onto a messenger is disclosed. The damper assembly comprises at least one damper weight with a forked side which accepts a messenger. A hole is drilled in the forked side of the damper weight to receive the messenger. A staking hole is then drilled into the bottom of the damper weights. The staking hole extends just past the side of the messenger hole and is sized to receive a staking ball. Staking of the damper weight is accomplished by pressing the staking ball into the staking hole via a hardened dowel pin to secure the messenger within the damper weights. | 10-02-2008 |
John Zaleski, Elkton, MD US
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20150213211 | Systems, Methods, User Interfaces and Analysis Tools for Supporting User-Definable Rules and Smart Rules and Smart Alerts Notification Engine - Computer implemented methods and systems operating on real-time data derived from a plurality of data sources for supporting user-definable rules and providing user notifications for providing user notifications and smart alarms. A user-interface configured to dynamically display a parameter and toggle between a tabular display and a graphical display is generated. At least one of a user-defined rule or a threshold value associated with the parameter from a user-interface element is received. A notification is provided to a user when the parameter satisfies the user-defined rule or exceeds the threshold value. | 07-30-2015 |
John R. Zaleski, Elkton, MD US
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20080249376 | Distributed Patient Monitoring System - A distributed patient monitoring system for visually monitoring patients and patient parameters using portable processing devices in different remote locations includes a monitoring processor. The monitoring processor is responsive to user initiated commands from multiple different portable processing devices in different remote locations and includes an input processor and a data processor. The input processor acquires vital sign parameters and associated video data representative of multiple sequences of video images of corresponding multiple different patients. The data processor processes the vital sign parameters and associated video data to provide processed first video data representing an image sequence including a composite image including a first area showing live video of a selected first patient and a second area presenting vital sign parameters of the selected first patient. The data processor also processes the vital sign parameters and associated video data to provide processed second video data representing an image sequence including a composite image including a first area showing live video of a selected second patient and a second area presenting vital sign parameters of the selected second patient. A communication network has bandwidth sufficient to communicate the processed first video data and second video data to first and second portable processing devices respectively of the multiple different portable processing devices in different remote locations in response to commands received from the first and second portable processing devices respectively. | 10-09-2008 |
20080249801 | Distributed System for Monitoring Patient Video, Audio and Medical Parameter Data - A system for use by a portable processing device operating in a distributed patient monitoring system for visually monitoring patients and patient parameters uses multiple portable processing devices in different remote locations. The system includes an authentication processor enabling a user to obtain access authorization to access patient data in response to entry of identification data using a portable processing device of the multiple portable processing devices in different remote locations. A user interface, in response to the access authorization, enables a user to, initiate execution of a clinical information system providing a user with a clinical application display image identifying multiple different patients in corresponding multiple different locations and select a particular patient of the multiple different patients in the clinical application display image. A data processor uses an identifier of the particular patient in acquiring access information associated with the particular patient from a repository and uses the access information in acquiring live video and vital sign parameters of the particular patient from a room associated with the particular patient. A display processor initiates generation of data representing an image sequence comprising a composite image including a first area showing acquired live video of the particular patient and a second area presenting acquired vital sign parameters of the particular patient in response to user selection of an image element associated with the particular patient of the multiple different patients in the clinical application display image. | 10-09-2008 |
20090262894 | Medical Imaging Processing and Care Planning System - A system automatically compares radiotherapy 3D X-Ray images and subsequent images for update and re-planning of treatment and for verification of correct patient and image association. A medical radiation therapy system and workflow includes a task processor for providing task management data for initiating image comparison tasks prior to performing a session of radiotherapy. An image comparator, coupled to the task processor, in response to the task management data, compares a first image of an anatomical portion of a particular patient used for planning radiotherapy for the particular patient, with a second image of the anatomical portion of the particular patient obtained on a subsequent date, by image alignment and comparison of image element representative data of aligned first and second images to determine an image difference representative remainder value and determines whether the image difference representative remainder value exceeds a first predetermined threshold. An output processor, coupled to the image comparator, initiates generation of an alert message indicating a need to review planned radiotherapy treatment for communication to a user in response to a determination the image difference representative remainder value exceeds a predetermined threshold. | 10-22-2009 |
John R. Zaleski, West Brandywine, PA US
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20090055735 | SYSTEMS USER INTERFACES AND METHODS FOR PROCESSING MEDICAL DATA - Illustrative embodiments comprise systems, user interfaces, and/or methods for automatically acquiring data representing a plurality of medical parameters of a patient, processing the data for presentation to a user via a display device, and initiating display of one or more image windows, which present processed data representing the plurality of medical parameters of the patient | 02-26-2009 |
Kenneth Zaleski, Westland, MI US
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20140294013 | SYSTEM AND METHOD FOR NETWORK PROVISIONING - Implementations described and claimed herein provided for a system for provisioning network resources. The system includes a network provisioning abstraction layer having an application interface for receiving network provisioning requests from applications and determine provisioning instructions for fulfilling the requests. Each of the received provisioning instructions is queued in a priority queuing system according to a request priority. The provisioning instructions for the highest priority requests are removed from the front of the queue and sent to a resource interface that relays the requests to the appropriate network resources. | 10-02-2014 |
Kenneth G. Zaleski, Dacula, GA US
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20080263426 | Method and apparatus for performing trellis coded modulation of signals for transmission on a TDMA channel of a cable network - A method and apparatus for performing trellis coded modulation of signals for transmission on a TDMA channel of a cable network, such as a DOCSIS cable network, is provided. In an embodiment, an upstream modulator portion of a cable modem receives burst data, selectively encodes the burst data for trellis coded modulation to generate encoded symbols, and modulates the encoded symbols for selective transmission over a time division multiple access (TDMA) channel or a synchronous code division multiple access (S-CDMA) channel of the cable network. | 10-23-2008 |
Linda Zaleski, Lewisburg, PA US
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20100212063 | MEDICAL MODESTY GARMENT - A medical modesty garment is disclosed which allows easy access to and removal from a patient's body while providing improved patient modesty and privacy. The medical modesty garment may comprise a lower garment shaped like shorts, and/or an upper garment shaped like a tee shirt. The medical modesty garment of the invention may comprise perforations that may be torn to provide selective access to a patient's body or that may be torn to easily remove the garment from the patient. | 08-26-2010 |
Mark A. Zaleski, Galway, NY US
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20150236106 | METHOD FOR CREATING SELF-ALIGNED TRANSISTOR CONTACTS - Embodiments of the present invention provide improved methods of contact formation. A self aligned contact scheme with reduced lithography requirements is disclosed. This reduces the risk of shorts between source/drains and gates, while providing improved circuit density. Cavities are formed adjacent to the gates, and a fill metal is deposited in the cavities to form contact strips. A patterning mask is then used to form smaller contacts by performing a partial metal recess of the contact strips. | 08-20-2015 |
20150287636 | TRANSISTOR CONTACTS SELF-ALIGNED IN TWO DIMENSIONS - Embodiments of the present invention provide an improved semiconductor structure and methods of fabrication that provide transistor contacts that are self-aligned in two dimensions. Two different capping layers are used, each being comprised of a different material. The two capping layers are selectively etchable to each other. One capping layer is used for gate coverage while the other capping layer is used for source/drain coverage. Selective etch processes open the desired gates and source/drains, while block masks are used to cover elements that are not part of the connection scheme. A metallization line (layer) is deposited, making contact with the open elements to provide electrical connectivity between them. | 10-08-2015 |
20150332959 | METHODS AND STRUCTURES FOR BACK END OF LINE INTEGRATION - Embodiments of the present invention provide a semiconductor structure for BEOL (back end of line) integration. A directed self assembly (DSA) material is deposited and annealed to form two distinct phase regions. One of the phase regions is selectively removed, and the remaining phase region serves as a mask for forming cavities in an underlying layer of metal and/or dielectric. The process is then repeated to form complex structures with patterns of metal separated by dielectric regions. | 11-19-2015 |
20160056075 | PRECUT METAL LINES - Embodiments of the present invention provide a method for cuts of sacrificial metal lines in a back end of line structure. Sacrificial Mx+1 lines are formed above metal Mx lines. A line cut lithography stack is deposited and patterned over the sacrificial Mx+1 lines and a cut cavity is formed. The cut cavity is filled with dielectric material. A selective etch process removes the sacrificial Mx+1 lines, preserving the dielectric that fills in the cut cavity. Precut metal lines are then formed by depositing metal where the sacrificial Mx+1 lines were removed. Thus embodiments of the present invention provide precut metal lines, and do not require metal cutting. By avoiding the need for metal cutting, the risks associated with metal cutting are avoided. | 02-25-2016 |
20160056104 | SELF-ALIGNED BACK END OF LINE CUT - Embodiments of the present invention provide a method for self-aligned metal cuts in a back end of line structure. Sacrificial Mx+1 lines are formed above metal Mx lines. Spacers are formed on each Mx+1 sacrificial line. The gap between the spacers is used to determine the location and thickness of cuts to the Mx metal lines. This ensures that the Mx metal line cuts do not encroach on vias that interconnect the Mx and Mx+1 levels. It also allows for reduced limits in terms of via enclosure rules, which enables increased circuit density. | 02-25-2016 |
20160064514 | BORDERLESS CONTACT FORMATION THROUGH METAL-RECESS DUAL CAP INTEGRATION - An improved semiconductor structure and methods of fabrication that provide improved transistor contacts in a semiconductor structure are provided. A first block mask is formed over a portion of the semiconductor structure. This first block mask covers at least a portion of at least one source/drain (s/d) contact location. An s/d capping layer is formed over the s/d contact locations that are not covered by the first block mask. This s/d capping layer is comprised of a first capping substance. Then, a second block mask is formed over the semiconductor structure. This second block mask exposes at least one gate location. A gate capping layer, which comprises a second capping substance, is removed from the exposed gate location(s). Then a metal contact layer is deposited, which forms a contact to both the s/d contact location(s) and the gate contact location(s). | 03-03-2016 |
20160093704 | METHOD FOR CREATING SELF-ALIGNED TRANSISTOR CONTACTS - Embodiments of the present invention provide improved methods of contact formation. A self aligned contact scheme with reduced lithography requirements is disclosed. This reduces the risk of shorts between source/drains and gates, while providing improved circuit density. Cavities are formed adjacent to the gates, and a fill metal is deposited in the cavities to form contact strips. A patterning mask is then used to form smaller contacts by performing a partial metal recess of the contact strips. | 03-31-2016 |
Mark A. Zaleski, Malta, NY US
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20160049481 | TRANSISTOR CONTACTS SELF-ALIGNED TWO DIMENSIONS - Embodiments of the present invention provide an improved semiconductor structure and methods of fabrication that provide transistor contacts that are self-aligned in two dimensions. Two different capping layers are used, each being comprised of a different material. The two capping layers are selectively etchable to each other. One capping layer is used for gate coverage while the other capping layer is used for source/drain coverage. Selective etch processes open the desired gates and source/drains, while block masks are used to cover elements that are not part of the connection scheme. A metallization line (layer) is deposited, making contact with the open elements to provide electrical connectivity between them. | 02-18-2016 |
Mark Alexander Zaleski, Galway, NY US
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20160049327 | METHODS OF FABRICATING BEOL INTERLAYER STRUCTURES - Methods are provided for fabricating an interlayer structure useful in, for instance, providing BEOL interconnect for circuit structures. The method includes, for instance, providing an interlayer structure, including: providing an uncured insulating layer above a substrate structure; forming an energy removal film over the uncured insulated layer; forming at least one opening through the energy removal film and extending at least partially into the uncured insulating layer; and applying energy to cure the uncured insulating layer, establishing a cured insulating layer, and decomposing in part the energy removal film, establishing a reduced thickness, energy removal film over the cured insulating layer, the interlayer structure including the cured insulating layer, and the applying energy decreasing an aspect ratio(s) of the one opening(s). In one implementation, the uncured insulating layer includes porogens which also decompose partially during applying energy to further improve the aspect ratio(s). | 02-18-2016 |
Mitchell J. Zaleski, Northbrook, IL US
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20090025196 | MACHINE TOOL FOR ASSEMBLING AND INSTALLING VERY SMALL AND LIGHTWEIGHT PARTS - A machine-tool module for inserting and staking very small and lightweight contacts in a support member such as an electrical switch finger is disclosed and claimed. The device comprises a rotatable escapement element having a transporter adapted to receive a contact at an escapement receiving position from a first guide. The escapement element bearing the contact then rotates between the receiving position and an escapement delivery position to deliver the contact to a second guide. An impeller system urges the contact along the second guide to the contact installation point. A fluid pressure differential across the contact when the contact is in the guide impels the contact to move along the guide. | 01-29-2009 |
Peter Zaleski, Poulsbo, WA US
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20080248308 | METHOD OF MAKING GRAPHITE-COATED PARTICULATE MATERIALS - An coated particulate is provided with a graphite-impregnated resin coating. The oil field particulates may comprise any of gravel-pack sand, granular betonite, ground Gilsonite, calcium carbonate, glass beads, rock wool, shredded paper, metal spheres, ceramic beads, nut hulls, ground rubber, plastic beads, muscovite mica, calcined petroleum coke, and perlite. The resin may comprise as a binder one or more of a natural, synthetic, water-soluble, and organic resins. More specifically, the resins may comprise an organic film-forming resin such as an alkyd, polyurethane and epoxy. Alternatively, the resin may comprise a film-forming water-soluble polymer, such as a starch, carboxymethyl cellulose, hydroxyethyl cellulose, and xanthan gum. In a further alternative, the resin may comprise a resin-dispersed emulsion, such as a latex or acrylic. | 10-09-2008 |