Yue, US
Baohua Yue, Ballwin, MO US
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20110207660 | PHARMACEUTICAL FORMULATIONS OF AN HCV PROTEASE INHIBITOR IN A SOLID MOLECULAR DISPERSION - The present invention provides pharmaceutical formulations of an HCV protease inhibitor in a solid dispersion with an excipient which provided advantageous pharmacokinetic properties for inhibiting or treating HCV infection. In preferred embodiments, the excipient is at least one polymer. The present invention also provides processes for manufacturing such formulations as well as uses of said composition for the manufacture of a medicament for treating or ameliorating one or more symptoms of HCV or disorders associated with HCV in a subject in need thereof using said formulations. | 08-25-2011 |
20140113970 | DISPENSING SYSTEM - The invention provides systems and methods for controlled dispensing of topical analgesics contained in a metered dispensing system. The systems and method are useful for treating signs and symptoms of osteoarthritis. The method includes depressing a hand pump to dispense a dose of a topical pain reliever in a viscous solution from the hand pump, wherein the hand pump is configured to dispense the dose within a tolerance specified by a corresponding label approved by a government regulatory agency; and spreading the topical solution on skin. | 04-24-2014 |
20160074351 | DISPENSING SYSTEM - The invention provides systems and methods for controlled dispensing of topical analgesics contained in a metered dispensing system. The systems and method are useful for treating signs and symptoms of osteoarthritis. The method includes depressing a hand pump to dispense a dose of a topical pain reliever in a viscous solution from the hand pump, wherein the hand pump is configured to dispense the dose within a tolerance specified by a corresponding label approved by a government regulatory agency; and spreading the topical solution on skin. | 03-17-2016 |
Beatrice Yue, Deerfield, IL US
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20090318537 | SILENCING OF TGF BETA TYPE II RECEPTOR EXPRESSION BY SIRNA - The present application is directed to siRNA-based silencing of the type II receptor of TGFβ. siRNAs that target this receptor abrogate the receptor protein and transcript, TGFβ-mediated processes such as fibronectin assembly and cell migration also are inhibited and the molecules of the invention are efficacious in reducing the inflammatory response and matrix deposition. These findings show that siRNAs can be successfully delivered both in vitro and in vivo to regulate the TGFβ type II receptor level and modulate wound response. Methods and compositions exploiting the findings of the present invention have a wide-ranging application, extending from treatment of disorders of the eye to other organs and tissues throughout the body. | 12-24-2009 |
Beatrice Y.j.t. Yue, Deerfield, IL US
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20100087486 | METHODS FOR USING TGF-B RECEPTOR INHIBITORS OR ACTIVIN-LIKE KINASE (ALK) 5 INHIBITORS A-83-01 AND SB-431542 TO TREAT EYE DISEASE AND WOUND HEALING CONDITIONS - A pharmaceutical composition useful in the prevention of subconjunctival scarring that may occur after glaucoma filtration surgery comprising an effective amount of an activin receptor-like kinase 5 inhibitor. Also disclosed is a method of treating corneal haze and subconjunctival scarring that may develop after ocular surgery comprising applying an amount of a pharmaceutical composition including an activin receptor-like kinase 5 inhibitor. | 04-08-2010 |
Bingfang Yue, North Wales, PA US
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20150212055 | Sensitive Method for Measuring Cis-Diol Containing Compounds in Plasma Using 2D-LC-MS/MS - The present invention provides methods for determining the amount of cis-diol containing compounds in a biological samples using mass spectrometry, particularly catecholamines (dopamine, epinephrine, norepinephrine) in a plasma sample. After a sample is mixed with an internal standard, extracted with a two-step liquid-liquid extraction process utilizing phenylboronic acid chemistry, and then derivatized with a benzoyl chloride-like agent, relevant moieties are then separated chromatographically and detected by MS/MS whereby specific ion transitions are monitored. This invention has several clinical utilities, particularly those related to measuring plasma catecholamines in patients. | 07-30-2015 |
Bingfang Yue, Cedar Hills, UT US
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20120126107 | Enhanced Sensitivity for Analysis of Carbonyl Containing Compounds Using Mass Spectrometry - The present disclosure provides methods and composition involving increased sensitivity of compounds using mass spectrometry. In one embodiment, a method of increasing the sensitivity for detection of a carbonyl group-containing compound by mass spectrometry can comprise derivatizing the carbonyl group-containing compound with an O-substituted hydroxylamine thereby producing an oxime, resulting in enhanced sensitivity of detection by mass spectrometry, as compared to the underivatized carbonyl group-containing compound. | 05-24-2012 |
Chaofang Yue, Midland, MI US
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20130274169 | ETHYLENE ACRYLIC ACID COPOLYMER AQUEOUS DISPERSIONS FOR FRAGRANCE RELEASE IN LAUNDRY DETERGENTS - Described are fabric care compositions, comprising a builder and an aqueous dispersion comprising an ethylene acrylic acid copolymer and a fragrance. | 10-17-2013 |
Cheisan Yue, Roseville, MN US
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20100006912 | Planar Metal-Insulator-Metal Circuit Element and Method for Planar Integration of Same - A complementary metal-oxide-semiconductor (CMOS) static random-access-memory (SRAM) element comprising a planar metal-insulator-metal (MIM) capacitor is disclosed, and the planar MIM capacitor is electrically connected to the transistors in the CMOS memory element to reduce the effects of charged particle radiation on the CMOS memory element. Methods for immunizing a CMOS SRAM element to the effects of charged particle radiation are also disclosed, along with methods for manufacturing CMOS SRAM including planar MIM capacitors as integrated circuits. | 01-14-2010 |
20100200918 | Heavy Ion Upset Hardened Floating Body SRAM Cells - A CMOS memory element comprising silicon-on-insulator MOSFET transistors is disclosed wherein at least one of the MOSFET transistors is configured such that the body of the transistor is not connected to a voltage source and is instead permitted to electrically float. Implementations of the disclosed memory element with increased immunity to errors caused by heavy ion radiation are also disclosed. | 08-12-2010 |
Cheisan J. Yue, Roseville, MN US
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20090302227 | Neutron Detection Structure - A neutron detection structure built from a Silicon-On-Insulator memory cell includes a conversion layer for converting incident neutrons into emitted charged particles, a device layer for receiving the emitted charged particles, a buried oxide layer separating the conversion layer from the device layer and directly adjacent to the conversion layer and the device layer, an isolation layer, a passivation layer formed on the isolation layer opposite the device layer and buried oxide layer, a carrier adhered by an adhesion layer to the passivation layer opposite the isolation layer, and a plurality of conductive contacts to provide electrical contact to the device layer. A corresponding method for fabricating such a structure includes permanently bonding a carrier to a passivated SOI SRAM wafer, removing an insulative substrate, depositing a conversion layer where at least a portion of the insulative substrate was removed, and forming at least one opening in the conversion layer and the buried oxide layer to provide at least one electrical contact to the device layer. | 12-10-2009 |
20110045652 | TECHNIQUES TO REDUCE SUBSTRATE CROSS TALK ON MIXED SIGNAL AND RF CIRCUIT DESIGN - An integrated circuit has a buried insulation layer formed over a semiconductor substrate, and a semiconductor mesa formed over the buried insulation layer. A low resistivity guard ring substantially surrounds the semiconductor mesa and is in contact with the semiconductor substrate. The low resistivity guard ring is grounded and isolates the semiconductor mesa from RF signals. | 02-24-2011 |
Chi Yau Yue US
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20080219318 | Mirror with non-invasive temperature sensing device - The embodiments of the invention provide a non-invasive temperature sensing device including a glass mirror and a temperature sensing device coupled to the glass mirror such that when a user is positioned in front of the glass mirror the temperature sensing device can sense the body temperature of the person. The temperature sensing device can be an infrared or laser thermometer. The device can include a base having an upright member coupled thereto, wherein the glass mirror is coupled to the upright member. The glass mirror can further include a temperature display coupled thereto. The device can also contain a processor and memory for processing and storing sensed temperatures. The temperature sensing device can alternatively be attached to either the base or the upright member. More than one temperature sensing device can be connected to the device. | 09-11-2008 |
Chuan Yue, Colorado Springs, CO US
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20120079575 | System Architecture and Method for Secure Web Browsing Using Public Computers - A secure web browsing method and web browsing security system architecture for a mobile device that has initiated an internet communication session via a local area network (LAN) are provided. The architecture establishes a communication link between the mobile device and a computer having an internet browser capable of internet communication via the LAN. A routine is transmitted from the mobile device to the computer via the communication link. The routine synchronizes page content of the mobile device to the computer's internet browser. The architecture (i) detects user-supplied inputs to the page content on the computer's internet browser, (ii) generates a verification request at the mobile device when at least a portion of the user-supplied inputs are so-detected, and (iii) transmits the user-supplied inputs from the mobile device as an internet communication via the LAN only when the verification request is confirmed by the user at the mobile device. The architecture also processes each new page loaded at the mobile device to perform at least one of removal and obfuscation of selected information associated with the new page in order to generate a modified page that is transmitted to the computer using the communication link. The page content of the computer's internet browser is updated to the modified page using the routine previously transmitted to the computer via the communication link. | 03-29-2012 |
Chuan Yue, Hampton, VA US
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20100082747 | REAL-TIME COLLABORATIVE BROWSING - A method, a system, and a computer-readable medium are provided which support a collaborative browsing session. A connection request is received at a first device from a second device. The connection request indicates a request for a collaborative browsing session between the first device and the second device. In response to the connection request, a web page is sent to the second device from the first device. The web page includes embedded computer-executable instructions to support the collaborative browsing session. A browser application at the first device is monitored for a change in state. An indicator of the change in state of the browser application is sent to the second device from the first device. | 04-01-2010 |
20110126289 | CLIENT SIDE USERNAME/PASSWORD CREDENTIAL PROTECTION - A method of protecting username/password (U/P) credentials operates on a client computer that cooperates with an anti-phishing scheme that generates a client warning at the client computer when a suspected phishing website issues a U/P request. At the client computer, a set of S fake U/P credentials is generated when the client warning is heeded, or a set of (S−1) fake U/P credentials are derived from a client-supplied U/P credential provided after the client warning is ignored. The client computer then transmits to the suspected phishing website one of (i) the set of S fake U/P credentials, and (ii) the client-supplied U/P credential along with the set of (S−1) fake U/P credentials. | 05-26-2011 |
David T. Yue, Baltimore, MD US
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20080279864 | High Throughput Screen Utilizing Newly Discovered Intramolecular Neuronal Calcium Channel Interactions To Discover New Analgesics - The present invention relates to compositions to treat Ca | 11-13-2008 |
Doufeng Yue, Plano, TX US
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20080311747 | METAL-GERMANIUM PHYSICAL VAPOR DEPOSITION FOR SEMICONDUCTOR DEVICE DEFECT REDUCTION - The present invention provides a method of manufacturing a metal silicide electrode ( | 12-18-2008 |
Duofeng Yue, Plano, TX US
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20100032801 | CAPACITOR FORMED IN INTERLEVEL DIELECTRIC LAYER - An capacitor is formed in an interlevel dielectric (ILD) layer of the integrated circuit (IC) by etching vertical trenches through the ILD and depositing conformal layers of a bottom electrode metal, a capacitor dielectric and a top electrode metal. The capacitor can attain a capacitance density of 20 nanofarads/mm | 02-11-2010 |
20100041241 | HIGH DENSITY PLASMA DIELECTRIC DESPOSITION FOR VOID FREE GAP FILL - A process for void free deposition of dielectric films over high aspect ratio structures using HDP CVD. In a dielectric liner deposition step and the etch to deposition ratio is increased and the deposition pressure is reduced to reduce the aspect ratio of the gap and to deposit a dielectric sidewall on the gap with a significant slope. | 02-18-2010 |
20140184381 | SINGLE PHOTOMASK HIGH PRECISION THIN FILM RESISTOR - An integrated circuit contains a thin film resistor in which a body of the thin film resistor is disposed over a lower dielectric layer in a system of interconnects in the integrated circuit. Heads of the thin film resistor are disposed over electrodes which are interconnect elements in the lower dielectric layer, which provide electrical connections to a bottom surface of the thin film resistor. Top surfaces of the electrodes are substantially coplanar with a top surface of the lower dielectric layer. A top surface of the thin film resistor is free of electrical connections. An upper dielectric layer is disposed over the thin film resistor. | 07-03-2014 |
Eddy W. Yue, Landenberg, PA US
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20090286778 | MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS - The present invention relates to macrocyclic compounds of Formula I: | 11-19-2009 |
20100015178 | 1,2,5-OXADIAZOLES AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-21-2010 |
20110183985 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS - The present invention provides fused aryl and heteroaryl derivatives of Formula I: | 07-28-2011 |
20110190319 | SUBSTITUTED HETEROARYL FUSED DERIVATIVES AS PI3K INHIBITORS - The present invention provides fused derivatives of Formula I: | 08-04-2011 |
20110281884 | FUSED DERIVATIVES AS PI3KDELTA INHIBITORS - The present invention provides fused derivatives that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases. | 11-17-2011 |
20110311479 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME - The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. | 12-22-2011 |
20120058079 | 1,2,5-Oxadiazoles as Inhibitors of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 03-08-2012 |
20120157430 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS - The present invention provides N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines derivatives that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases. | 06-21-2012 |
20130059835 | HETEROCYCLYLAMINES AS PI3K INHIBITORS - The present invention provides heterocyclylamine derivatives of Formula I: | 03-07-2013 |
20130123246 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME - The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. | 05-16-2013 |
20140023663 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-23-2014 |
20140057912 | PYRIMIDINE-4,6-DIAMINE DERIVATIVES AS PI3K INHIBITORS - The present invention provides pyrimidine-4,6-diamine derivatives of Formula (I): wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases. | 02-27-2014 |
20140066448 | SUBSTITUTED DIAMINO-PYRIMIDINE AND DIAMINO-PYRIDINE DERIVATIVES AS PI3K INHIBITORS - The present invention provides substituted diamino-pyrimidine and substituted diamino-pyridine derivatives of Formula I; wherein X, Y, R | 03-06-2014 |
20140249132 | USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K-DELTA RELATED DISORDERS - The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I: | 09-04-2014 |
20140275127 | SUBSTITUTED HETEROARYL FUSED DERIVATIVES AS PI3K INHIBITORS - The present invention provides fused derivatives of Formula I: | 09-18-2014 |
20140315962 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 10-23-2014 |
20140377292 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME - The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. | 12-25-2014 |
20150148342 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS - The present invention relates to bicyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer. | 05-28-2015 |
20150148372 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS - The present invention relates to bicyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer. | 05-28-2015 |
20150148375 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS - The present invention relates to bicyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer. | 05-28-2015 |
20150190378 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 07-09-2015 |
20150284390 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS - The present invention provides N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines derivatives that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases. | 10-08-2015 |
20160022685 | HETEROCYCLYLAMINES AS PI3K INHIBITORS - The present invention provides heterocyclylamine derivatives of Formula I: | 01-28-2016 |
20160024117 | HETEROCYCLYLAMINES AS PI3K INHIBITORS - The present invention provides heterocyclylamine derivatives of Formula I: | 01-28-2016 |
Eddy Wai Tsun Yue, Landenberg, PA US
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20080214546 | N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to N-hydroxyamidino compounds which are modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. | 09-04-2008 |
20100190804 | MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS - The present invention relates to macrocyclic compounds of Formula I: | 07-29-2010 |
20110172279 | N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to N-hydroxyamidino compounds which are modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. | 07-14-2011 |
20110251215 | MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS - The present invention relates to macrocyclic compounds of Formula I: | 10-13-2011 |
Eddy Way Tsun Yue, Landenberg, PA US
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20110165188 | N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to N-hydroxyamidino compounds which are modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof. | 07-07-2011 |
Felicia Yue, Yorktown Heights, NY US
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20090128548 | IMAGE REPAIR INTERFACE FOR PROVIDING VIRTUAL VIEWPOINTS - A system and method for repairing an object in image data of an event. An image of the event is obtained from a camera, and an object is detected in the image. For example, the event may be a sporting event in which the object is a participant. Moreover, a portion of the object is occluded in a viewpoint of the camera. For instance, a limb of the participant may be occluded by another participant. The object is repaired by providing a substitute for the occluded portion. A user may perform the repair via a user interface by selecting part of an image from an image library and positioning the selected portion relative to the object. A textured 3d model of the event is combined with data from the repaired object, to depict a realistic virtual viewpoint of the event which differs from a viewpoint of the camera. | 05-21-2009 |
20090128549 | FADING TECHNIQUES FOR VIRTUAL VIEWPOINT ANIMATIONS - In one aspect, an image of an event is obtained from a camera, and an object is detected in the image. Data of a textured 3d model of the event and data from the object are combined to depict virtual viewpoints of the event which differ from a real viewpoint of the camera. The object is at least partially faded out at a virtual viewpoint which meets a specified criterion, such as a specified angular offset, or exceeding a specified difference from the viewpoint of the camera. The fading can occur over multiple virtual viewpoints, or over a time period in which the fading is otherwise apparent to a human viewer. In another aspect, an animation is provided in which one object is faded out at a specified virtual viewpoint so that it does not fully occlude another object. For instance, the objects can be participants in a sports event. | 05-21-2009 |
20090128563 | USER INTERFACE FOR ACCESSING VIRTUAL VIEWPOINT ANIMATIONS - A user such as a television viewer is provided with the capability to view an event from different virtual viewpoints which differ from the viewpoint of a camera. In one aspect, the user is informed of particular camera images from which a virtual viewpoint can be viewed. For example, a menu interface may provide thumbnail preview images of the one or more particular camera images. In another aspect, the use enters commands to manipulate a virtual viewpoint, such as by rotating around a point, moving a lookout point and zooming in or out. In response, a display is provided which includes a textured 3d model of the event combined with at least one textured object in the event. For instance, the event may be a sporting event and the at least one textured object may be a participant in the sporting event. | 05-21-2009 |
20090128568 | VIRTUAL VIEWPOINT ANIMATION - In one aspect, images of an event are obtained from a first video camera and a second camera, where the second camera captures images at a higher resolution than the first video camera. A particular image of interest is identified from the images obtained by the first video camera, e.g., based on an operator's command. A corresponding image which has been obtained by the second camera is then identified. The second image is used to depict virtual viewpoints which differ from the real viewpoints of the first and second camera, such as by combining data from a textured 3d model of the event with data from the second image. In another aspect, a presentation includes images from a first camera, followed by an animation of different virtual viewpoints, followed by images from a second camera which has a different real viewpoint of the event than the first camera. | 05-21-2009 |
20090128577 | UPDATING BACKROUND TEXTURE FOR VIRTUAL VIEWPOINT ANIMATIONS - Image data of an event is provided by updating a textured 3d model of the event. For example, in a sporting event, a model of a stadium can be periodically updated to reflect changes over time in lighting, advertisements, number of spectators in the stands and so forth. Different virtual viewpoints of the event can be depicted in an animation using the textured 3d model and image data from objects at the event such as participants in the sporting event. The same image from which object data is obtained can also be used to update the textured 3d model so that the model is current in the animation, resulting in greater realism. The updating can be based on an operator command or automatic detection of a specified event, such as change in lighting or passage of time. The animation can be provided in a broadcast television signal. | 05-21-2009 |
20090128667 | LINE REMOVAL AND OBJECT DETECTION IN AN IMAGE - In one aspect, lines in image data of an event are automatically found and repaired. For example, the event may be a sporting event which is played on a field, and the line segment is a field line on the field which may be obscured by a player, game ball or other object. The line segment is automatically detected in a mask image, and a portion of the line segment which is occluded by the object is automatically determined, and the object is automatically removed. The line segment can also be repaired. Optionally, a virtual viewpoint of the event is provided from the image, with the line repaired and the object removed. In another aspect, an object in an image of an event is automatically located by detecting blobs in the image which meet at least one specified criterion, such as size, aspect ratio, density or color profile. | 05-21-2009 |
Feng Yue, Sammamish, WA US
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20090168105 | Spooling Strategies Using Structured Job Information - Spooling strategies are described for producing job information that conforms to a hierarchical structure, and then storing the job information in a spool storage. The job information is then retrieved from the spool storage and consumed. The structured job information includes a multi-level hierarchy of nodes, including a job level that represents the entire job, a document level that represents a document to be processed within the job; a rendition level that represents a rendition of the document to be processed; and a page level that represents a page associated with the rendition. In addition, filter logic processes job information based on capabilities of a target entity utilizing the job information. | 07-02-2009 |
20120147414 | MULTISOURCE, ADAPTIVE PRINTER CONFIGURATION - Some embodiments of the invention provide techniques whereby a printer driver may be modified and supplemented over time. For example, a framework may be provided which enables a printer driver's functionality to be supplemented over time to include new and/or enhanced features, such as features relating to the manner in which the capabilities of a printer are configured, print settings are manipulated, information is presented to users, print-related system events are handled, etc. In some embodiments, one or more components (which may be included in a print subsystem provided by an operating system of a computing device, in a printer driver, and/or some other system element) may be configured to automatically seek and acquire configuration data from any of various sources, including the printer device, one or more online sources, and/or other sources. | 06-14-2012 |
20120147415 | PRINTER DRIVER AND APPLICATION DECOUPLING USING EVENT CENTRIC REGISTRATION MODEL - Some embodiments of the invention provide a printer user interface (UI) component configured to handle presentation of information to a user during printing operations. The printer UI component may de-couple the rendering and configuration functionality provided by a printer driver from the presentation of information to end users, thereby reducing the risk that applications may crash or hang due to printer driver malfunction. In some embodiments, a registry of events upon which information should be presented to the user is established, and the printer UI component may be registered for some or all of these events, so that when the specified events occur the printer UI component may be invoked to cause information to be presented to the user. | 06-14-2012 |
20120307288 | PRINTING USING A PLATFORM-INDEPENDENT DRIVER - In one or more embodiments, a print server can publish, to client devices, capabilities and configurations of one or more print devices utilizing a device-independent “personality.” Client devices can then use an associated device-independent print driver to select print job settings and record print job content for a particular print job, in a device-independent format, that is then to be sent to the print server. The print server can then process the device-independent format that describes the print job, and convert the print job into a print device-specific format that can be consumed by a particular specific print device. In at least some embodiments, the client device can cause a print job to be printed on a print device, via a print server, without downloading, utilizing or otherwise accessing a print driver that is specific to the print device. | 12-06-2012 |
20150022859 | MULTI-SOURCE, ADAPTIVE PRINTER DRIVER CONFIGURATION - Some embodiments of the invention provide techniques whereby a printer driver may be modified and supplemented over time. For example, a framework may be provided which enables a printer driver's functionality to be supplemented over time to include new and/or enhanced features, such as features relating to the manner in which the capabilities of a printer are configured, print settings are manipulated, information is presented to users, print-related system events are handled, etc. In some embodiments, one or more components (which may be included in a print subsystem provided by an operating system of a computing device, in a printer driver, and/or some other system element) may be configured to automatically seek and acquire configuration data from any of various sources, including the printer device, one or more online sources, and/or other sources. | 01-22-2015 |
20160048357 | PRINTER DRIVER AND APPLICATION DECOUPLING USING EVENT CENTRIC REGISTRATION MODEL - Some embodiments of the invention provide a printer user interface (UI) component configured to handle presentation of information to a user during printing operations. The printer UI component may de-couple the rendering and configuration functionality provided by a printer driver from the presentation of information to end users, thereby reducing the risk that applications may crash or hang due to printer driver malfunction. In some embodiments, a registry of events upon which information should be presented to the user is established, and the printer UI component may be registered for some or all of these events, so that when the specified events occur the printer UI component may be invoked to cause information to be presented to the user. | 02-18-2016 |
20160078644 | Graphics Primitive and Color Channels - Graphics primitive and color channel techniques are described. In one or more implementations, image data is processed by a computing device to form a plurality of pixels and corresponding one or more color channels usable to define a color for a respective said pixel. A graphics primitive type is identified by the computing device associated with one or more of the pixels in the processed image data. The graphics primitive type is assigned by the computing device to the one or more pixels using at least one color channel. | 03-17-2016 |
20160094386 | MULTI-ENROLLMENTS OF A COMPUTING DEVICE INTO CONFIGURATION SOURCES - Various technologies described herein pertain to managing multiple enrollments of a computing device into configuration sources. Respective enrollment types for the enrollments into the configuration sources can be detected. Moreover, respective control data for the enrollments into the configuration sources can be set based on the enrollment types. Provisioning elements (e.g., policies, preferences, configuration profiles, and resources) that satisfy the respective control data can be permitted to be applied to the computing device by the configuration sources as part of the enrollments. Further, disparate provisioning elements that fail to satisfy the respective control data can be prevented from being applied to the computing device as part of the enrollments. | 03-31-2016 |
Gaofeng Yue, Atlanta, GA US
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20090201844 | Method, Apparatus And System For Multicast Communication In A Wireless Multi-Hop Network - A method for multicast communication in a network having plural nodes according to the ZigBee network specification includes creating a multicast group including a subset of the plural nodes and excluding at least one non-member node in the plural nodes. The multicast group has a multicast address. The method also includes transmitting multicast message including the multicast address and receiving the multicast message at each node in the multicast group. | 08-13-2009 |
Guosen Yue, Edison, NJ US
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20140270023 | Low-Complexity Estimation of QAM Symbols and Constellations - Disclosed are methods and structures for soft symbol and variance estimation for QAM constellations including a big-flipping framework and efficient methods for soft symbol estimation and variance estimation for QAM. Disclosed are efficient Gray mapping which provides a much lower complexity, i.e., log N for N-QAM for both squared and non-squared QAM constellations. Also disclosed is an approximation method that avoids multiplications completely while exhibiting only a slight performance degradation. Finally, a low complexity method for variance estimations, particularly second moment estimations for both squared and non-squared QAM constellations with Gray mapping are disclosed. Advantageously—using the disclosed methods—the complexity of the second moment estimation is reduced to O((log N)̂2) for an N-QAM symbol for both squared and non-squared QAM. | 09-18-2014 |
20150063254 | LOW-COMPLEXITY PRECODER DESIGN FOR LARGE-SCALE MIMO COMMUNICATION SYSTEMS - A method and system are provided. The method includes providing transmit precoders for a multiple-input and multiple-output communication system having a plurality of transmit antennas. The plurality of transmit antennas are for forming, using precoding, a plurality of channels such that each of the plurality of channels are configurable to serve a respective one of a plurality of users. The providing step includes imposing a respective average transmit antenna power constraint on each of the plurality of transmit antennas. The providing step further includes determining a diagonal precoder responsive to applying column scaling to a downlink channel matrix having a plurality of rows and a plurality of columns. The providing step additionally includes generating, from the diagonal precoder, a weighted precoder in accordance with the respective average antenna power constraint by optimizing a weighted sum-rate obtained upon transmitting respective signals over the plurality of channels. | 03-05-2015 |
20150092556 | TWO-STAGE PRECODING AND USER GROUPING FOR LARGE SCALE MULTIPLE-INPUT MULTIPLE-OUTPUT (MIMO) SYSTEMS - Methods are provided. A method includes determining respective weighted likelihoods corresponding to a plurality of users in a multiple-input multiple-output communication system. The method further includes forming a plurality of user groups from the plurality of users using an iterative K-means clustering technique applied to the plurality of users. The iterative K-means clustering technique is responsive to the respective weighted likelihoods. | 04-02-2015 |
Guosen Yue, Princeton, NJ US
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20110064015 | RETRANSMISSION PROTOCOL AND CODING SCHEME FOR MULTICAST BROADCAST SERVICE - A method for the retransmission and coding of multicast broadcast services. | 03-17-2011 |
20140044061 | Coordinated Multipoint Transmission and Reception (CoMP) - A communications method implemented in a transmission point (TP) used in a coordinated multipoint transmission and reception (CoMP) system is disclosed. The communications method comprises transmitting, to a user equipment (UE), attributers for up to four indicators indicating at least physical downlink shared channel (PDSCH) resource element (RE) mapping, and transmitting, to the UE, one of the four indicators, each of which is conveyed in 2 bits, wherein the four indicators comprises ‘00’, ‘01’, ‘10’, and ‘11’ corresponding to a first set, a second set, a third set, and a fourth set of parameters, respectively. Other methods, apparatuses, and systems are also disclosed. | 02-13-2014 |
20140045510 | Coordinated Multipoint Transmission and Reception (CoMP) - A communications method implemented in a transmission point (TP) used in a coordinated multipoint transmission and reception (CoMP) system is disclosed. The communications method includes transmitting, to a user equipment (UE), an indication of a channel state information (CSI) process in a CSI pattern comprising a set of CSI processes, wherein the UE is configured with the CSI process for at least one of the other CSI processes in the CSI pattern, and wherein a reported rank indication (RI) for the CSI process is the same as an RI for said at least one of the other CSI processes. Other methods, apparatuses, and systems are also disclosed. | 02-13-2014 |
20150043499 | Coordinated Multipoint Transmission and Reception (CoMP) - A wireless communications method implemented in a network system that supports coordinated multipoint transmission and reception (CoMP) is disclosed. The wireless communications method includes informing a user equipment (UE) semi-statically of a codebook subset for each channel state information (CSI) process, wherein the UE is restricted to report an indication of a precoding matrix within the codebook subset. Other methods, apparatuses, and systems are also disclosed. | 02-12-2015 |
Guozhen Yue, Troy, MI US
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20100116334 | VHF ENERGIZED PLASMA DEPOSITION PROCESS FOR THE PREPARATION OF THIN FILM MATERIALS - A VHF energized plasma deposition process wherein a process gas is decomposed in a plasma so as to deposit the thin film material onto a substrate, is carried out at process gas pressures which are in the range of 0.5-2.0 torr, with substrate temperatures that do not exceed 300° C., and substrate-cathode spacings in the range of 10-50 millimeters. Deposition rates are at least 5 angstroms per second. The present method provides for the high speed deposition of semiconductor materials having a quality at least equivalent to materials produced at a much lower deposition rate. | 05-13-2010 |
20100117172 | THIN FILM SEMICONDUCTOR ALLOY MATERIAL PREPARED BY A VHF ENERGIZED PLASMA DEPOSITION PROCESS - A thin film, hydrogenated, silicon based semiconductor alloy material is produced by a VHF energized plasma deposition process wherein a process gas is decomposed in a plasma so as to deposit the thin film material onto a substrate. The process is carried out at process gas pressures which are in the range of 0.5-2.0 torr, with substrate temperatures that do not exceed 300° C., and substrate-cathode spacings in the range of 10-50 millimeters. Deposition rates are at least 5 angstroms per second. Also disclosed are photovoltaic devices which include the semiconductor material. | 05-13-2010 |
Hongyu Yue, Austin, TX US
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20120225568 | ANNEALING METHOD AND ANNEALING APPARATUS - An annealing method irradiates a target object, having a film formed on its surface, with a laser beam to perform an annealing process to the target object. The surface of the target object is irradiated with the laser beam obliquely at an incident angle that is determined to achieve an improved laser absorptance of the film. | 09-06-2012 |
Hongyu H. Yue, Plano, TX US
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20110186443 | Electrochemical substrate slicing using electromagnetic wave excitation - An apparatus for cutting a workpiece using electrochemical etching and a method of using thereof are described. The apparatus includes an electrochemical bath configured to contain an electrochemical solution, a support apparatus configured to support and immerse a workpiece in the electrochemical bath, and a non-contact cutting device configured to extend into the electrochemical bath and slice the workpiece via electrochemical etching along a cutting plane. The apparatus further includes an electromagnetic (EM) radiation source configured to illuminate a cutting surface formed between opposing sidewalls within an evolving cutting groove formed in the workpiece during slicing along the cutting plane. | 08-04-2011 |
20150137006 | MULTI-STEP LOCATION SPECIFIC PROCESS FOR SUBSTRATE EDGE PROFILE CORRECTION FOR GCIB SYSTEM - Disclosed are an apparatus, system, and method for scanning a substrate or other workpiece through a gas-cluster ion beam (GCIB), or any other type of ion beam. The workpiece scanning apparatus is configured to receive and hold a substrate for irradiation by the GCIB and to scan it through the GCIB in two directions using two movements: a reciprocating fast-scan movement, and a slow-scan movement. The slow-scan movement is actuated using a servo motor and a belt drive system, the belt drive system being configured to reduce the failure rate of the workpiece scanning apparatus. | 05-21-2015 |
Hongyu Henry Yue, Plano, TX US
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20130084655 | OVERLAY MEASUREMENT FOR A DOUBLE PATTERNING - A multi-patterning method of manufacturing a patterned wafer provides test structures designed to enhance overlay error measurement sensitivity for monitoring and process control. One or more patterns are overlaid on a first pattern, each of a given pitch, with the elements interleaved. Test structure is formed with elements of the overlaid patterns spaced away from respective mid-positions more closely toward elements of the first pattern. In some embodiments, test structure elements of the second pattern are overlaid midway between mid-positions of elements of the first pattern and measured by scatterometry. In other embodiments, test structure elements of the second pattern are overlaid at a slightly different pitch than the elements of the first pattern and measured by reflectivity. Measurements are compared with library measurements to identify the error, which may be fed back to control the patterning process. The multi-patterning may be formed by LELE, LLE, LFLE, or other methods. | 04-04-2013 |
20150152556 | METHOD AND DEVICE FOR CONTROLLING PATTERN AND STRUCTURE FORMATION BY AN ELECTRIC FIELD - A processing method and apparatus uses at least one electric field applicator ( | 06-04-2015 |
Hoong Pak Jinji Yue, Dublin, OH US
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20140100118 | METHOD FOR CONTINUOUSLY FORMING SUPERCONDUCTING WIRE AND PRODUCTS THEREFROM - A device and method for continuously forming superconducting wire, and products made therefrom. The method may include providing at least one continuous metal sheathing strip and at least one metal form, continuously forming the at least one continuous metal sheathing strip to form a partially open configuration, continuously filling the partially open configuration with magnesium diboride precursor comprising boron, and a metal form, and closing the partially open configuration thereby enclosing the magnesium diboride precursor comprising boron, and a metal form, to form a closed configuration. Subsequent reduction in diameter and elongation in length of the closed configuration, followed by heat treatment, catalyzes the transformation of the magnesium diboride precursor comprising boron, and the metal form, to magnesium diboride to form the superconducting wire. | 04-10-2014 |
James Yue, New Haven, CT US
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20120265251 | CONICAL INTERSPINOUS APPARATUS AND A METHOD OF PERFORMING INTERSPINOUS DISTRACTION - A conical interspinous apparatus includes a distractor comprising an insertion portion and a central engagement groove, the insertion portion having a conical shape which tapers to a tip and is adapted to enable passage of the distractor between two spinous processes of vertebrae, and the central engagement groove is adapted to secure the distractor between the two spinous processes such that the two spinous processes rest in the central engagement groove. The conical interspinous apparatus includes a stabilizer which is adapted to be deployed from within the distractor to secure the two spinous processes within the central engagement groove and an insertion driver detachably coupled to a rear portion of the distractor. A guide wire, having a pointed tip, aids in the insertion of the distractor between the two spinous processes and is configured to guide the insertion of the distractor. | 10-18-2012 |
James J. Yue, Guilford, CT US
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20100057130 | CONICAL INTERSPINOUS APPARATUS AND A METHOD OF PERFORMING INTERSPINOUS DISTRACTION - A conical interspinous apparatus includes a distractor comprising an insertion portion and a central engagement groove, the insertion portion having a conical shape which tapers to a tip and is adapted to enable passage of the distractor between two spinous processes of vertebrae, and the central engagement groove is adapted to secure the distractor between the two spinous processes such that the two spinous processes rest in the central engagement groove. The conical interspinous apparatus includes a stabilizer which is adapted to be deployed from within the distractor to secure the two spinous processes within the central engagement groove and an insertion driver detachably coupled to a rear portion of the distractor. A guide wire, having a pointed tip, aids in the insertion of the distractor between the two spinous processes and is configured to guide the insertion of the distractor. | 03-04-2010 |
20100106191 | CONICAL INTERSPINOUS APPARATUS AND A METHOD OF PERFORMING INTERSPINOUS DISTRACTION - A conical interspinous apparatus comprising: an insertion portion with a proximal end, a distal end, and conical screw-shaped grooves configured to distract two adjacent spinous processes; a shaft portion, coupled to the distal end of the insertion portion, and having a smaller cross-section than a cross-section at the distal end of the insertion portion, such that the two spinous processes rest on the shaft portion; and a clamp portion being movable and securable along the shaft, and being configured to secure the two spinous processes between the clamp portion and the distal end of the insertion portion. | 04-29-2010 |
20120265246 | CONICAL INTERSPINOUS APPARATUS AND A METHOD OF PERFORMING INTERSPINOUS DISTRACTION - A conical interspinous apparatus comprising: an insertion portion with a proximal end, a distal end, and conical screw-shaped grooves configured to distract two adjacent spinous processes; a shaft portion, coupled to the distal end of the insertion portion, and having a smaller cross-section than a cross-section at the distal end of the insertion portion, such that the two spinous processes rest on the shaft portion; and a clamp portion being movable and securable along the shaft, and being configured to secure the two spinous processes between the clamp portion and the distal end of the insertion portion. | 10-18-2012 |
20130018465 | SPINAL FUSION DEVICES AND A METHOD OF PERFORMING SPINAL FUSION - A spinal fusion apparatus includes a cage body configured to be inserted between two vertebral bodies and which has internal sidewalls that define a cavity which extends vertically through the cage body, and an internal compression member which includes a movable sidewall which defines at least one side of the cavity, and which is movable in a lateral direction from a first position located in the cavity to a second position located in the cavity such that a space within the cavity is reduced when the movable sidewall is at the second position. The internal compression member includes a compression mechanism coupled to the moveable sidewall, and moves the movable sidewall from the first position to the second position. Fusion material is disposed in the cavity is compressed and compacted by the movable sidewall as the moveable sidewall moves from the first position to the second position. | 01-17-2013 |
20130018472 | SPINAL FUSION DEVICES AND A METHOD OF PERFORMING SPINAL FUSION - A spinal fusion apparatus includes a cage body configured to be inserted between two vertebral bodies and which has internal sidewalls that define a cavity which extends vertically through the cage body, and an internal compression member which includes a movable sidewall which defines at least one side of the cavity, and which is movable in a lateral direction from a first position located in the cavity to a second position located in the cavity such that a space within the cavity is reduced when the movable sidewall is at the second position. The internal compression member includes a compression mechanism coupled to the moveable sidewall, and moves the movable sidewall from the first position to the second position. Fusion material is disposed in the cavity is compressed and compacted by the movable sidewall as the moveable sidewall moves from the first position to the second position. | 01-17-2013 |
Jianhui Yue, Old Town, ME US
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20150340091 | EXPLOITING PCM WRITE ASYMMETRIES TO ACCELERATE WRITE - To improve the write performance of PCM, the disclosed technology, in certain embodiments, provides a new write scheme, referred to herein as two-stage-write, which leverages the speed and power asymmetries of writing a zero bit and a one bit. Writing a data block to PCM is divided into two separated stages, i.e., write-0 stage and write-1 stage. Without violating power constraints, during the write-0 stage, all zero bits in this data block are written to PCM at an accelerated speed; during the write-1 stage, all one bits are written to PCM, with more bits being written concurrently. In certain embodiments, the disclosed technology provides a new coding scheme to improve the speed of the write-1 stage by further increasing the number of bits that can be written to PCM in parallel. | 11-26-2015 |
Jianpeng Yue, Sugar Land, TX US
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20150308206 | SYSTEM AND METHOD FOR SETTING A COMPLETION TOOL - The system and method for setting a completion tool within a wellbore includes assembling a mandrel, inner sleeve, piston, outer sleeve, and dog member. In a first locked position, the dog member abuts against the indentation of the mandrel and the locking surface of the piston. The dog member is friction fit between the piston and mandrel so that movement of the completion tool corresponds to movement of the mandrel. The mechanical link, such as shear pins, of the completion tool is protected by the dog member holding steady on the mandrel. When the completion tool reaches the desired location, a pressure pulse opens a chamber between the sleeves to transition to a second released position. The dog member releases from the mandrel to be housed in the chamber, when movement of the mandrel sets the completion tool by the mechanical link, such as shear pins. | 10-29-2015 |
Jianpeng "jim" Yue, Sugar Land, TX US
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20150136403 | BALL SEAT SYSTEM - The system and method for hydraulic fracturing includes a downhole tool with a sub, a sleeve, a ball seat support, and a ball seat holder. A ball dropped through the wellbore sits on the ball interface of the ball seat holder. Fluid flowing through the system pushes the ball against the ball interface, causing the ball seat holder to slide through the ball seat support and the ball interface to clamp the ball. A ball matches only a particular ball interface. Additional pressure forms a seal of the ball, the ball seat holder, and the ball seat support and moves the sleeve to slide through the sub and expose the throughbore to the annulus for the fracturing. Contact distributed between the ball, ball interface of the ball seat holder, and ball seat support withstands the temperature and pressure of the fracturing without deformation or failure of the ball. | 05-21-2015 |
Joe Yue, Plano, TX US
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20110242295 | Three dimension image display method - Disclosed is a three dimensional image display method and some application structures. The three dimensional display method employs one piece of flat mirror to separate an observer's right and left eyes while flipping one image, either right or left, to overlay with another to render a vivid three dimensional image. The method does not need eyeglasses, does not need to see through any optical elements, has no limit to the field of view, and is the most nature method for observers to view a three dimensional image just as to view the real world with naked eyes. | 10-06-2011 |
Kan Yue, Akron, OH US
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20150315348 | SUB-10-NANOMETER NANOSTRUCTURES ENGINEERED FROM GIANT SURFACTANTS - A process of forming a nanopatterned substrate is provided. The process comprising the steps of first preparing a giant surfactant comprising a cage-like molecular nanoparticle head linked to a polymer chain tail through a chemical linkage. Next, using the giant surfactant, a thin film is formed. Next the thin film formed from the giant surfactant is annealed such that the giant surfactant self-assembles into a desired nanostructure. The desired nanostructure is comprised of periodic major domains and minor domains. Finally, at least some of either the major domain or the minor domain is selectively removed to form the nanopatterned substrate. | 11-05-2015 |
Kathy Yue, Minneapolis, MN US
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20120177681 | Formulation of immunopotentiators - Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminium salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention time, and/or immunostimulatory effect. Immunopotentiators are modified to introduce a moiety, such as a phosphonate group, which can mediate adsorption. These modified compounds can retain or improve their in vivo immunological activity even when delivered in an adsorbed form. | 07-12-2012 |
20130274465 | ADSORPTION OF IMMUNOPOTENTIATORS TO INSOLUBLE METAL SALTS - Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminium salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention time, and/or immunostimulatory effect. Immunopotentiators are modified to introduce a moiety, such as a phosphonate group, which can mediate adsorption. These modified compounds can retain or improve their in vivo immunological activity even when delivered in an adsorbed form. | 10-17-2013 |
Lan Yue, Chicago, IL US
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20130237899 | Nanoscale Neuromodulating Platform for Retina Neuron Activation Apparatus and Method - The present invention relates to methods and compositions for modulating receptors in postsynaptic neurons of damaged or diseased retinas. The invention also related to methods for using the compositions set forth herein for treatment of diseases of hyperexcitability such as epilepsy. | 09-12-2013 |
Li Yue, Philadelphia, PA US
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20110144569 | PERITONEAL DIALYSIS MACHINE TOUCH SCREEN USER INTERFACE - A peritoneal dialysis machine including a membrane pump and a touch screen display that includes a mode-indicating portion and an operation-descriptive portion, the mode-indicating portion having a plurality of touch sensitive indicia each indicating one of a plurality of modes in which the machine can operate, the display being used to keep a patient continually informed of which one mode of at least three operating modes the machine is operating in, as the operation-descriptive portion changes to display details of a specific operation being carried out within the one mode, the indicia for each of the three operating modes always being visible to the patient while the machine is operating, the operating mode being selected by the patient touching one of the indicia on the screen. | 06-16-2011 |
20120035533 | PERITONEAL DIALYSIS MACHINE TOUCH SCREEN USER INTERFACE - A peritoneal dialysis machine including a membrane pump and a touch screen display that includes a mode-indicating portion and an operation-descriptive portion, the mode-indicating portion having a plurality of touch sensitive indicia each indicating one of a plurality of modes in which the machine can operate, the display being used to keep a patient continually informed of which one mode of at least three operating modes the machine is operating in, as the operation-descriptive portion changes to display details of a specific operation being carried out within the one mode, the indicia for each of the three operating modes always being visible to the patient while the machine is operating, the operating mode being selected by the patient touching one of the indicia on the screen. | 02-09-2012 |
20130324915 | STEPPER MOTOR DRIVEN PERITONEAL DIALYSIS MACHINE - A peritoneal dialysis system includes: an enclosure including an actuation surface and a door; a stepper motor housed by the enclosure; a pump head and a solid pump piston structurally linking the pump head to the stepper motor; and a disposable unit accepted by the enclosure, the disposable unit including a flexible membrane attached to a rigid piece, the actuation surface of the enclosure and the disposable unit so configured and arranged that when the stepper motor turns and consequently translates the solid pump piston and the pump head towards the door, the pump head physically contacts and stretches the membrane from a relaxed position to a stretched position, and when the stepper motor turns and consequently translates the solid pump piston and the pump head away from the door, the membrane follows the pump head and transitions from the stretched position to the relaxed position. | 12-05-2013 |
Li Yue, North Wales, PA US
Patent application number | Description | Published |
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20130331775 | PERITONEAL DIALYSIS SYSTEMS AND METHODS HAVING GRAPHICAL USER INTERFACE - A peritoneal dialysis machine including a membrane pump and a touch screen display that includes a mode-indicating portion and an operation-descriptive portion, the mode-indicating portion having a plurality of touch sensitive indicia each indicating one of a plurality of modes in which the machine can operate, the display being used to keep a patient continually informed of which one mode of at least three operating modes the machine is operating in, as the operation-descriptive portion changes to display details of a specific operation being carried out within the one mode, the indicia for each of the three operating modes always being visible to the patient while the machine is operating, the operating mode being selected by the patient touching one of the indicia on the screen. | 12-12-2013 |
Li Yue, Princeton, NJ US
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20080243824 | System and method for associating a geographic location with an internet protocol address - Systems and methods for associating a geographic location with an IP address are disclosed. Generally, a plurality of localized search queries of search queries received at an Internet search engine are determined, where each of the plurality of localized search queries is associated with a location. A geo tag is associated with each of the plurality of localized search queries and a subset of the plurality of localized search queries that are associated with a first IP address is identified. The subset of the plurality of localized search queries is clustered into a spatial cluster including localized search queries associated with geo tags located within a defined distance of a geo tag associated with at least one other localized search query of the cluster. A geographic location associated with a geographic center of the cluster is then associated with the first IP address. | 10-02-2008 |
20090037602 | System and Method for Merging Internet Protocol Address to Location Data from Multiple Sources - Systems and methods for associating a geographic location with an Internet protocol (IP address) are disclosed. Generally, an IP address to location module determines whether a geographic location is associated with a common IP address in a majority of IP address to location data sets. The IP address to location module then stores an association between a geographic location and the IP address in a master IP address to location data set based on whether a geographic location is associated with a common IP address in a majority of IP address to location data sets. | 02-05-2009 |
Meghan Lynn Yue, Johnson Creek, WI US
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20090092307 | SLIT COLLIMATOR SCATTER CORRECTION - A technique is presented for establishing a patient's BMD using a dual-energy X-ray imaging system. In the technique, the dual-energy X-ray imaging system utilizes a slit collimator to expose a series of portions of a region of interest within a patient with X-rays of two different energies. A flat-panel digital X-ray detector detects the X-rays passing through the patient's region of interest and produces data representative of the intensity of the X-rays reaching the detector. The image intensity data is corrected for scatter based on identifying the regions of the image intensity data that are produced from scatter only, and not primary X-rays. A first-order derivative of the image intensity data is used to identify these regions. A value for the intensity of the scatter at the boundary of the scatter-only region is established. The value for the intensity of the scatter at the boundary of the scatter-only region is used to estimate scatter intensity in the region of the image intensity data that is produced from primary X-rays, as well as scatter. To correct the image intensity data for scatter, the known and estimated scatter intensities are subtracted from the image intensity data. | 04-09-2009 |
20120163557 | METHODS AND PHANTOMS FOR CALIBRATING AN IMAGING SYSTEM - A method for calibrating a medical imaging system includes performing an initial calibration of the imaging system, at a manufacturing site fabricating the imaging system, using a plurality of phantoms, shipping one of the phantoms to an installation site installing the imaging system, and performing a final calibration, at an installation site of the imaging system, using the shipped phantom. A set of calibration phantoms is also described herein. | 06-28-2012 |
Pei Yue, Redmond, WA US
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20130212103 | RECORD LINKAGE BASED ON A TRAINED BLOCKING SCHEME - Some implementations disclosed herein provide techniques and arrangements to train a blocking scheme using both labeled data and unlabeled data. For example, training the blocking scheme may include iteratively: learning a conjunction, identifying first matches in the labeled data and the unlabeled data that are uncovered by the conjunction, and identifying second matches in the labeled data and the unlabeled data that are covered by the conjunction. The conjunction learned in each iteration may be combined using a disjunction. A search engine may use the search engine when searching for records that match an entity. | 08-15-2013 |
Samuel K. Yue, Edina, MN US
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20080300172 | Method and Compositions for the Treatment of Diabetes and Related Complications - The present invention relates to administration of relaxin and related polypeptides to treat a variety of conditions, including diabetes, diabetes-related conditions, Alzheimer's disease, and menopause and related conditions. | 12-04-2008 |
Shi Yue, Ithaca, NY US
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20120037814 | ELECTRIC FIELD-GUIDED PARTICLE ACCELERATOR, METHOD, AND APPLICATIONS - A charged particle accelerator having a curvilinear beam trajectory maintained solely by a laterally directed, constant electric field; requiring no magnetic field. A method for controlling the trajectory of a charged particle in an accelerator by applying only a constant electric field for beam trajectory control. Curvilinear steering electrodes held at a constant potential create the beam path. A method for making a chip-scale charged particle accelerator involves integrated circuit-based processes and materials. A particle accelerator that can generate 110 KeV may a footprint less than about 1 cm | 02-16-2012 |
Simon C. Yue, Brookline, MA US
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20120164138 | USE OF ANTI-CD1 ANTIBODIES FOR THE MODULATION OF IMMUNE RESPONSES - The invention provides methods for the administration of an anti-CD1 antibody for the treatment or prevention of a variety of disorders, such as autoimmune disease, viral infection, bacterial infection, parasitic infection, infection by a eukaryotic pathogen, allergy, asthma, inflammatory condition, graft versus host disease, graft rejection, immunodeficiency disease, spontaneous abortion, pregnancy, and cancer. | 06-28-2012 |
20150231234 | USE OF ANTI-CD1 ANTIBODIES FOR THE MODULATION OF IMMUNE RESPONSES - The invention provides methods for the administration of an anti-CD1 antibody for the treatment or prevention of a variety of disorders, such as autoimmune disease, viral infection, bacterial infection, parasitic infection, infection by a eukaryotic pathogen, allergy, asthma, inflammatory condition, graft versus host disease, graft rejection, immunodeficiency disease, spontaneous abortion, pregnancy, and cancer. | 08-20-2015 |
Soon Pak Shinji Yue, Westford, MA US
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20120077184 | ELECTROMAGNETIC MULTIPLEX ASSAY BIOSENSOR - A method is provided for determining the presence of multiple different target analytes in a liquid sample using electrophoretic separation and magnetic labels within a self-contained reaction cartridge and an external magnetic sensor for detection. Magnetic labels are bound to target analytes through specific binding elements. By electrophoretic separation, the multiple different targets can be sorted according to their specific sizes and inherent molecular charges for better detection resolution and specificity. After the separation process, the target analytes are then recognized and trapped by the detection binding elements within the reaction cartridge. A magnetic field generator provides a changeable magnetic field that causes the bounded magnetic labels and target analytes to produce a resonance disruption detectable by a magnetic sensor. The sensor can provide a digital binary value to indicate whether or not a label particle is bound and that determines the presence of target analytes. | 03-29-2012 |
Stephen T. Yue, Eugene, OR US
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20080254501 | CHEMICAL PROBE COMPOUNDS THAT BECOME FLUORESCENT UPON REDUCTION, AND METHODS FOR THEIR USE - Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction, the quenching properties of the quenching unit are diminished or eliminated. The chemical compounds can be used in a variety of applications, including the detection of bacterial cells, monitoring the electron transport chain function of bacterial cells, monitoring the oxidation state of non-biological systems, and assaying the effectiveness of antibacterial or antimicrobial agents. | 10-16-2008 |
20100143917 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE - Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA. | 06-10-2010 |
20110117591 | CHEMICAL PROBE COMPOUNDS THAT BECOME FLUORESCENT UPON REDUCTION, AND METHODS FOR THEIR USE - Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction, the quenching properties of the quenching unit are diminished or eliminated. The chemical compounds can be used in a variety of applications, including the detection of bacterial cells, monitoring the electron transport chain function of bacterial cells, monitoring the oxidation state of non-biological systems, and assaying the effectiveness of antibacterial or antimicrobial agents. | 05-19-2011 |
20110217696 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES - Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms. | 09-08-2011 |
20110217699 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use - Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA. | 09-08-2011 |
20120004397 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE - The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the preparation of dye-conjugates. | 01-05-2012 |
20120288855 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use - Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA. | 11-15-2012 |
20120295817 | Aza-benzazolium Containing Cyanine Dyes - Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms. | 11-22-2012 |
Tai-Yuen Yue, Hockessin, DE US
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20100015178 | 1,2,5-OXADIAZOLES AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-21-2010 |
20120058079 | 1,2,5-Oxadiazoles as Inhibitors of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 03-08-2012 |
20140023663 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-23-2014 |
20140315962 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 10-23-2014 |
20150190378 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 07-09-2015 |
Tingting Yue, Cary, NC US
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20110257029 | BIOMARKERS FOR PANCREATIC CANCER AND DIAGNOSTIC METHODS - Methods and related kits for differentiating pancreatic cancer from a benign pancreatic disease. The method includes assaying a patient biological sample for a total level of CA 19-9 antigen and for a glycan level in specific mucin(s), and comparing the total level of CA 19-9 antigen and the glycan level in the specific mucin(s) to statistically validated thresholds, wherein a different level of total CA 19-9 antigen in the patient biological sample as compared to a statistically validated threshold and a different level of glycan level in the specific mucin(s) as compared to statistically validated thresholds indicate pancreatic cancer in the patient rather than a benign pancreatic disease. | 10-20-2011 |
Weimin Yue, Warsaw, IN US
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20110105640 | Bone cement having porous fiber reinforcement - The bone cement matrix consists of three base component parts, which when mixed form a radiopaque rapidly setting bone cement, namely, a powdered or granular low viscosity polymer component; a liquid reactive or polymerizable monomer component; and a reinforcement component consisting of porous ceramic fibers. The ceramic fibers are porous and have a rough outer surface created by the pores and cavity permeating the fibers. The pores, cavities and rough surface of the fibers themselves, provide the mechanical interface for securely bonding the fibers to the polymer component. During polymerization, the polymer component saturates into the pores and cavities of the ceramic fibers creating a positive interdigitation of the polymer and fibers within the cement matrix. | 05-05-2011 |
Xiao Allison Yue, Belle Mead, NJ US
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20160068720 | HIGH TEMPERATURE DEBONDABLE ADHESIVE - A debondable adhesive composition comprises (A) the hydrosilation reaction product of the reaction between the vinyl groups on 1,3,5,7-tetravinyl-1,3,5,7-tetramethylcyclotetra-siloxane and the terminal Si—H hydrogens on a silane or siloxane having terminal Si—H hydrogens, (B) a cross-linker for the hydrosilation reaction product, and (C) a metal catalyst and/or a radical initiator. In further embodiments, this invention is an assembly of a substrate and a carrier for the substrate in which the debondable adhesive composition is disposed between the substrates, and a method for fabricating that assembly. The debondable adhesive composition maintains its adhesion at temperatures of 300° C. or greater, and is mechanically debondable at room temperature at a force less than 5N/25 mm. | 03-10-2016 |
Xuan Yue, Dallas, TX US
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20100273863 | Modulation of Gene Expression Using Oligomers That Target Gene Regions Downstream of 3' Untranslated Regions - Gene expression can be selectively modulated by contacting a cell with an oligomer that targets a gene region downstream of a ′3-UTR, thereby increasing or decreasing the expression of the target gene. | 10-28-2010 |
Xuyi Yue, Gaithersburg, MD US
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20130197271 | DENDRIMERS AND METHODS OF PREPARING SAME THROUGH PROPORTIONATE BRANCHING - The present invention provides for monodispersed dendrimers having a core, branches and periphery ends, wherein the number of branches increases exponentially from the core to the periphery end and the length of the branches increases exponentially from the periphery end to the core, thereby providing for attachment of chemical species at the periphery ends without exhibiting steric hindrance. | 08-01-2013 |
Yisong Yue, Pittsburgh, PA US
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20160092769 | ANALYSIS OF TEAM BEHAVIORS USING ROLE AND FORMATION INFORMATION - Approaches are described for discovering a formation associated with an agent group engaging in an activity over a window of time. A formation analysis system computes first and second results for an objective function based on first and second sets of role assignments for each agent in the agent group at first and second moments in time, respectively. The formation analysis system iterates by: replacing the first set of role assignments with the second set of role assignments, and determining whether completion criteria have been met based at least in part on comparing the first result with the second result. If the completion criteria have not been met, then the formation analysis system replaces the second set of role assignments with a third set of role assignments that associate each agent in the first agent group with a different role assignment in the third set of role assignments at a third moment in time. If the completion criteria have been met, then the formation analysis system determines the first formation based on the second result. | 03-31-2016 |
Yongping Yue, Columbia, MO US
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20080249052 | Synthetic mini/micro-dystrophin genes to restore nNOS to the sarcolemma - The present invention provides novel dystrophin mini/micro-genes that retain the essential biological functions of a full-length dystrophin gene. More particularly, the present invention provides to a series of synthetic mini/micro-dystrophin genes capable of restoring neuronal nitric oxide synthase (nNOS) to the sarcolemma. A method as well as a pharmaceutical composition for treatment of Duchenne Muscular Dystrophy (DMD), Becker Muscular Dystrophy (BMD), and X-linked Dilated Cardiomyopathy (XLDC) are also provided. | 10-09-2008 |
20100003218 | HYBRID-AAV VECTORS TO DELIVER LARGE GENE EXPRESSION CASSETTE - Hybrid adeno-associated virus (AAV) vector systems able to efficiently express therapeutic target genes larger than may be carried in a single AAV vector are provided, wherein a highly recombinogenic foreign DNA sequence is incorporated into two or more ITR-mediated AAV vectors. In one aspect of one embodiment, the novel hybrid AAV vector system is a hybrid dual AAV (hdAAV) vector system. In another aspect of one embodiment, the novel hybrid AAV vector system is a hybrid tri AAV (htAAV) vector system. A method of treating a clinical disease caused at least in part by a defective gene is provided, and comprises (1) providing a hybrid AAV vector system capable of expressing a therapeutic target gene, wherein the therapeutic target gene is capable of replacing, restoring or counteracting the effects of the defective gene; and (2) administering a therapeutic amount of said vector system to a subject wherein said therapeutic target gene is expressed at levels having a therapeutic effect. | 01-07-2010 |
20140234255 | MICRODYSTROPHIN PEPTIDES AND METHODS FOR TREATING MUSCULAR DYSTROPHY USING THE SAME - According to the embodiments described herein, a series of biological materials for treatment/therapy of DMD and/or BMD through the recovery of sarcolemmal nNOS is provided. The biological material comprises the complete dystrophin repeats R16 and R17 or certain domains, sections, or fragments of the dystrophin repeats R16 and R17. In some aspects, such domains, sections, or fragments may be selected from sequence motifs including dystrophin R17 α1 helix, α2 and α3 helices of both R16 and R17, or a combination thereof. | 08-21-2014 |
Yun Yue, Melbourne, FL US
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20080266959 | MEMORY ARRAY OF FLOATING GATE-BASED NON-VOLATILE MEMORY CELLS - A memory array comprises a plurality of memory cells organized in a matrix of rows and columns. Each of the memory cells includes a high voltage access transistor, a floating gate memory transistor electrically connected to the access transistor, and a coupling capacitor electrically connected to the memory transistor. A first set of word lines are each electrically connected to the capacitor in each of the memory cells in a respective row. A second set of word lines are each electrically connected to the access transistor in each of the memory cells in a respective row. A first set of bit lines are each electrically connected to the access transistor in each of the memory cells in a respective column. A second set of bit lines are each electrically connected to the memory transistor in each of the memory cells in a respective column. Various combinations of voltages can be applied to the word lines and bit lines in operations to program, erase, read, or inhibit a logic state stored by the memory transistor in one or more of the memory cells. | 10-30-2008 |
20110116318 | MEMORY ARRAY OF FLOATING GATE-BASED NON-VOLATILE MEMORY CELLS - A memory array comprises a plurality of memory cells organized in a matrix of rows and columns. Each of the memory cells includes a high voltage access transistor, a floating gate memory transistor electrically connected to the access transistor, and a coupling capacitor electrically connected to the memory transistor. A first set of word lines are each electrically connected to the capacitor in each of the memory cells in a respective row. A second set of word lines are each electrically connected to the access transistor in each of the memory cells in a respective row. A first set of bit lines are each electrically connected to the access transistor in each of the memory cells in a respective column. A second set of bit lines are each electrically connected to the memory transistor in each of the memory cells in a respective column. Various combinations of voltages can be applied to the word lines and bit lines in operations to program, erase, read, or inhibit a logic state stored by the memory transistor in one or more of the memory cells. | 05-19-2011 |
20110116319 | MEMORY ARRAY OF FLOATING GATE-BASED NON-VOLATILE MEMORY CELLS - A memory array comprises a plurality of memory cells organized in a matrix of rows and columns. Each of the memory cells includes a high voltage access transistor, a floating gate memory transistor electrically connected to the access transistor, and a coupling capacitor electrically connected to the memory transistor. A first set of word lines are each electrically connected to the capacitor in each of the memory cells in a respective row. A second set of word lines are each electrically connected to the access transistor in each of the memory cells in a respective row. A first set of bit lines are each electrically connected to the access transistor in each of the memory cells in a respective column. A second set of bit lines are each electrically connected to the memory transistor in each of the memory cells in a respective column. Various combinations of voltages can be applied to the word lines and bit lines in operations to program, erase, read, or inhibit a logic state stored by the memory transistor in one or more of the memory cells. | 05-19-2011 |
20110116324 | MEMORY ARRAY OF FLOATING GATE-BASED NON-VOLATILE MEMORY CELLS - A memory array comprises a plurality of memory cells organized in a matrix of rows and columns. Each of the memory cells includes a high voltage access transistor, a floating gate memory transistor electrically connected to the access transistor, and a coupling capacitor electrically connected to the memory transistor. A first set of word lines are each electrically connected to the capacitor in each of the memory cells in a respective row. A second set of word lines are each electrically connected to the access transistor in each of the memory cells in a respective row. A first set of bit lines are each electrically connected to the access transistor in each of the memory cells in a respective column. A second set of bit lines are each electrically connected to the memory transistor in each of the memory cells in a respective column. Various combinations of voltages can be applied to the word lines and bit lines in operations to program, erase, read, or inhibit a logic state stored by the memory transistor in one or more of the memory cells. | 05-19-2011 |
Zhenyu Yue, New York, NY US
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20120041175 | NOVEL AUTOGRAPHY REGULATORS ATG14L AND RUBICON - The present invention provides for up- and down-regulation of cellular autophagy, e.g., for treating cancer or neurological disease. The invention results, in part, from discovery of two novel proteins, ATG14L (previously called “BISC”) and Rubicon (previously called “BIRC”), which bind to a Class III phophatidylinositol 3′-kinase (PI3K)/Vps34-Beclin 1 autophagic complex. ATG14L and Rubicon each regulate autophagic activity in an opposing manner. ATG14L and Rubicon can be used, for example, to increase/decrease autophagic activity, to increase/decrease PI3K/Vps34 kinase activity, and in so doing, treat diseases and disorders, such as cancer, neurodegenerative disease, stroke, metabolic disease, and age-related disease. ATG14L can increase autophagic activity and PI3K/Vps34 kinase activity; and Rubicon can decrease autophagic activity and PI3K/Vps34 kinase activity. | 02-16-2012 |
Zhongren Yue, Urbana, IL US
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20110064609 | HIGH SURFACE AREA CERAMIC COATED FIBERS - A method of manufacturing a ceramic coated fiber comprises heat treating an activated carbon coated fiber containing a ceramic precursor, to form a ceramic coated fiber. | 03-17-2011 |
Zuzhou Yue, Plano, TX US
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20160025929 | OPTICAL TAP - An optical tap includes a support with a first port facing a first ferrule supporting a first fiber along a first axis. A beamsplitter is connected to the support and intersected by the first axis. A second port is fastened to the support and facing a second ferrule supporting a second fiber along a second axis that intersects the beamsplitter. A third port is fastened to the support and facing a third ferrule supporting a third fiber along a third axis that intersects the beamsplitter, wherein the beamsplitter splits a first light signal from the first port to sends first and second portions of the first signal to the second and third ports, respectively. When the beamsplitter may optionally be configured as a polarizing element and include elements configured to rotate relative to each other to change a ratio of the first and second portions. The optical tap may optionally include a light intensity controlling device located in an optical path between the beamsplitter and at least one of the second or third ferrules. Optionally, a first collimating lens is configured to expand a first light beam that is substantially aligned with the first axis, and a second collimating lens is located between the beamsplitter and the second port, and configured to contract the second portion of the expanded first light beam to the second port. | 01-28-2016 |