Patent application number | Description | Published |
20120277579 | INTER-FRAME COMPLEX OCT DATA ANALYSIS TECHNIQUES - Techniques for collecting and processing complex OCT data to detect localized motion contrast information with enhanced accuracy and sensitivity are presented. In a preferred embodiment, vector differences between complex OCT signals taken at the same location on the sample are used to detect blood flow in the retina. Additional embodiments involving non-linear intensity weighting of the motion contrast information, normalization of the vector difference amplitudes, and calculating the absolute value of the standard deviation of Doppler signal are described. Image processing techniques to enhance the images resulting from these motion contrast techniques are also presented. | 11-01-2012 |
20130010302 | SYSTEMS AND METHODS FOR IMPROVED BALANCED DETECTION IN OPTICAL COHERENCE TOMOGRAPHY IMAGING - Systems and methods for reducing noise in balanced detection based optical coherence tomography (OCT) systems are described. Embodiments including both optical hardware and electronic based solutions to spectrally filter and attenuate the source reference light in optical coherence tomography in an effort to reduce RIN and FPN noise in OCT systems are presented. A novel application to electronic balanced detection schemes in which a single source of reference detection is balanced against the interferometric signals from multiple interferometers is also presented. | 01-10-2013 |
20130100456 | SYSTEMS AND METHODS FOR SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY - Systems and methods for increasing the duty cycle and/or producing interleaved pulses of alternating polarization states in swept-source optical coherence tomography (OCT) systems are considered. Embodiments including improved buffering, frequency selecting filter sharing among multiple SOAs, intracavity switching, and multiple wavelength bands are described. The unique polarization properties of the source configurations have advantages in speckle reduction, polarization-sensitive measurements, polarization state dependent phase shifts, spatial shifts, and temporal shifts in OCT measurements. | 04-25-2013 |
20130120757 | METHODS, SYSTEMS AND APPLICATIONS OF VARIABLE IMAGING DEPTH IN FOURIER DOMAIN OPTICAL COHERENCE TOMOGRAPHY - Systems, methods and applications for adjusting the imaging depth of a Fourier Domain optical coherence tomography system without impacting the axial resolution of the system are presented. One embodiment of the invention involves changing the sweep rate of a swept-source OCT system while maintaining the same data acquisition rate and spectral bandwidth of the source. Another embodiment involves changing the data acquisition rate of a SS-OCT system while maintaining the same sweep rate over the same spectral bandwidth. Several applications of variable imaging depth in the field of ophthalmic imaging are described. | 05-16-2013 |
Patent application number | Description | Published |
20090004238 | IMPLANTATION OF ENCAPSULATED BIOLOGICAL MATERIALS FOR TREATING DISEASES - Methods of applying biocompatible coating materials around biological materials using photopolymerization while maintaining the pre-encapsulation status of the biological materials are disclosed. The coatings can be placed directly onto the surface of the biological materials or onto the surface of other coating materials that hold the biological materials. The components of the polymerization reactions that produce the coatings can include natural and synthetic polymers, macromers, accelerants, cocatalysts, photoinitiators, and radiation. Methods of utilizing these encapsulated biological materials to treat different human and animal diseases or disorders by implanting them into several areas in the body including the subcutaneous site are also disclosed. The coating materials can be manipulated to provide different degrees of biocompatibility, protein diffusivity characteristics, strength, and biodegradability to optimize the delivery of biological materials from the encapsulated implant to the host recipient while protecting the encapsulated biological materials from destruction by the host inflammatory and immune protective mechanisms without requiring long-term anti-inflammatory or anti-immune treatment of the host. | 01-01-2009 |
20100112691 | Stem Cell Aggregate Suspension Compositions and Methods of Differentiation Thereof - The present invention relates to methods for production of undifferentiated or differentiated embryonic stem cell aggregate suspension cultures from undifferentiated or differentiated embryonic stem cell single cell suspensions and methods of differentiation thereof. | 05-06-2010 |
20110278755 | POROGEN COMPOSITIONS, METHOD OF MAKING AND USES - The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices. | 11-17-2011 |
20120045830 | STEM CELL AGGREGATE SUSPENSION COMPOSITIONS AND METHODS OF DIFFERENTIATION THEREOF - The present invention relates to methods for production of undifferentiated or differentiated embryonic stem cell aggregate suspension cultures from undifferentiated or differentiated embryonic stem cell single cell suspensions and methods of differentiation thereof. | 02-23-2012 |
20120077891 | POROGEN COMPOSITIONS, METHODS OF MAKING AND USES - Provided are porogen compositions and methods of using such porogen compositions in the manufacture of porous materials, for example, porous silicone elastomers. The porogens generally include comprising a core material and shell material different from the core material. The porogens can be used to form a scaffold for making a resulting porous elastomer when the scaffold is removed. | 03-29-2012 |
20130096081 | DERMAL FILLER COMPOSITIONS - The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent. | 04-18-2013 |
20130116188 | IMPLANTABLE HYALURONIC ACID/COLLAGEN COMPOSITIONS - Hyaluronic acid and collagen may be crosslinked in aqueous solution as described herein. The crosslinked macromolecular matrices obtained in this process may be used as a hydrogel for implants and fillers for human aesthetic and therapeutic products. | 05-09-2013 |
20130116190 | HYALURONIC ACID-COLLAGEN MATRICES FOR TISSUE ENGINEERING - Hydrogels comprising a macromolecular matrix including a crosslinked combination of hyaluronic acid and collagen, are provided for tissue engineering applications. | 05-09-2013 |
20130116411 | METHODS OF MAKING HYALURONIC ACID/COLLAGEN COMPOSITIONS - Hyaluronic acid and collagen may be crosslinked in aqueous solution as described herein. The crosslinked macromolecular matrices obtained in this process may be used as a hydrogel for implants and fillers for human aesthetic and therapeutic products. | 05-09-2013 |
20130123210 | DERMAL FILLER COMPOSITIONS INCLUDING ANTIOXIDANTS - Provided are injectable, hyaluronic acid-based hydrogel compositions including conjugated vitamins. | 05-16-2013 |
20130129835 | CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION - Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component. | 05-23-2013 |
20130203696 | DERMAL FILLER COMPOSITIONS FOR FINE LINE TREATMENT - The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face. | 08-08-2013 |
20130210760 | DERMAL FILLER COMPOSITIONS INCLUDING ANTIOXIDANTS - Provided are injectable, hyaluronic acid-based dermal filler compositions including conjugated vitamin C derivatives. The compositions provide for extended release of active vitamin C into tissue, promoting collagenesis and other benefits to skin. | 08-15-2013 |
20130244943 | HYALURONIC ACID-COLLAGEN MATRICES FOR DERMAL FILLING AND VOLUMIZING APPLICATIONS - Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen. | 09-19-2013 |
20140011980 | METHODS FOR STERILIZING COMPOSITIONS AND RESULTING COMPOSITIONS - Method for sterilizing a hydrogel composition include subjecting the composition to pulsed light comprising broadband spectrum radiation, the pulsed light being at a dose effective to sterilize the composition without causing significant change in rheology of the composition. | 01-09-2014 |
20140094433 | DERMAL FILLER HYDROGELS WITH VITAMIN A/CYCLODEXTRIN INCLUSION COMPLEXES - Compositions, such as hydrogel compositions, that include a hyaluronic acid, a vitamin A, and a cyclodextrin may be used as medical or cosmetic fillers, implants, or creams. For example, the compositions may be used as dermal fillers. | 04-03-2014 |
20140154508 | POROGEN COMPOSITIONS, METHODS OF MAKING AND USES - The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices. | 06-05-2014 |
20140315828 | CROSS-LINKED SILK-HYALURONIC ACID COMPOSITIONS - Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions. | 10-23-2014 |
20150057381 | POROGEN COMPOSITIONS, METHODS OF MAKING AND USES - Provided are porogen compositions and methods of using such porogen compositions in the manufacture of porous materials, for example, porous silicone elastomers. The porogens generally include comprising a core material and shell material different from the core material. The porogens can be used to form a scaffold for making a resulting porous elastomer when the scaffold is removed. | 02-26-2015 |
20150064147 | CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION - Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component. | 03-05-2015 |
Patent application number | Description | Published |
20090058395 | Method for Determining Anisotropy of 1-D Conductor or Semiconductor Synthesis - A method is provided for determining the anisotropy of alignment of a random array of 1-D conductive elements (e.g., carbon nanotube or silicon nanowire) formed on a substrate. A pattern of a plurality of electrodes are arranged on the substrate containing the 1-D conductive elements and a plurality of electrical property measurements are performed in a plurality of different directions between the plurality of electrodes. The plurality of measurements are combined together to generate a total measurement sum of electrical property measurements between the various electrodes. The measured electrical property is determined between a selected pair of the plurality of electrodes along a selected direction extending between the selected pair of electrodes. The anisotropy of alignment of the 1-D conductive elements on the substrate along the selected direction is determined based on a ratio of the measured electrical property between the selected pair of electrodes versus the total measurement sum. | 03-05-2009 |
20090116696 | SYSTEM, METHOD AND MACHINE-READABLE MEDIUM FOR CHARACTERIZING NANOTUBE MATERIALS - A computer implemented method of characterizing a nanotube material by sampling a region of the nanotube material using a scanning electron microscope (SEM) to obtain at least one image, and analyzing the at least one image using an image processing algorithm to characterize the nanotube material. | 05-07-2009 |
20090173516 | NANOTUBES AS MICROWAVE FREQUENCY INTERCONNECTS - The present invention provides nanotube interconnects capable of carrying current at high frequencies for use as high-speed interconnects in high frequency circuits. It is shown that the dynamical or AC conductance of single-walled nanotubes equal their DC conductance up to at least 10 GHZ, demonstrating that the current carrying capacity of nanotube interconnects can be extended into the high frequency (microwave) regime without degradation. Thus, nanotube interconnects can be used as high-speed interconnects in high frequency circuits, e.g., RF and microwave circuits, and high frequency nano-scale circuits. In a preferred embodiment, the nanotube interconnects comprise metallic single-walled nanotubes (SWNTs), although other types of nanotubes may also be used, e.g., multi-walled carbon nanotubes (MWNTs), ropes of all metallic nanotubes, and ropes comprising mixtures of semiconducting and metallic nanotubes. Applications for the nanotube interconnects include both digital and analog electronic circuitry. | 07-09-2009 |
20090189146 | Multifinger Carbon Nanotube Field-Effect Transistor - A multifinger carbon nanotube field-effect transistor (CNT FET) is provided in which a plurality of nonotube top gated FETs are combined in a finger geometry along the length of a single carbon nanotube, an aligned array of nanotubes, or a random array of nanotubes. Each of the individual FETs are arranged such that there is no geometrical overlap between the gate and drain finger electrodes over the single carbon nanotube so as to minimize the Miller capacitance (Cgd) between the gate and drain finger electrodes. A low-K dielectric may be used to separate the source and gate electrodes in the multifinger CNT FET so as t further minimize the Miller capacitance between the source and gate electrodes. | 07-30-2009 |
20100132883 | SYNTHESIS OF PURE NANOTUBES FROM NANOTUBES - An improved method of synthesizing nanotubes that avoids the slow process and the impurities or defects that are usually encountered with regard to as-grown carbon nanotubes. In a preferred embodiment, nanotubes are synthesized from nanotubes providing a novel catalyst-free growth method for direct growth of single- or multi-walled, metallic or semiconducting nanotubes. | 06-03-2010 |
20120273781 | Device and Method For RF Characterization of Nanostructures and High Impedance Devices - A method and device are provided for the RF characterization of nanostructures and high impedance devices. A two-terminal electronic nanostructure device is fabricated by dividing a length of a nanostructure into a plurality of shorter, identical nanostructures using a plurality of finger electrodes electrically connected in parallel. The nanostructure may include a single walled carbon nanotube subdivided into shorter identical copies of a metallic nanotube segment by situating multiple finger electrodes along the length of the single walled carbon nanotube. Each of the subdivided shorter nanotube segments are connected in parallel. This arrangement allows for close impedance matching to radio frequency (RF) systems, and serves as an important technique in understanding and characterizing metallic (and even semiconducting) nanotubes at RF and microwave frequencies. | 11-01-2012 |