Patent application number | Description | Published |
20080230167 | Adhesive and method for binding artificial plastic teeth - The present invention is directed toward an adhesive for and a method for bonding artificial plastic teeth to a denture base. The adhesive employs a number of adhesion promoter monomers, dimers or oligomers and a cure package, as well as methyl acetate as a solvent. The method according to the invention includes exposing a plastic tooth to the adhesive and allowing the plastic to soften (not dissolve). The adhesion promoter chains infiltrate the plastic tooth matrix, such that upon curing a secure bond is formed. | 09-25-2008 |
20090130624 | Methods and kits for making flexible dental guards - Dental guards, particularly night guards, used by patients to protect their teeth against the effects of grinding and bruxism are provided. Methods and kits for making such dental guards are also included. A light-curable polymerizable arch material is used to fabricate the dental guard. Preferably, the material contains polymerizable acrylic compounds, color-changing cure indicator, and particulate filler. The material is molded to conform to the shape of a dental arch of a patient and light-cured to form the dental guard. | 05-21-2009 |
20110081627 | Methods for making provisional and long-term dental crowns and bridges - The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, crowns and bridges. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office. A polymerizable dental composite material, which is dimensionally shape-stable in its uncured state, is used to make the restoration. A substructure such as a metal coping can be used to support the polymerizable material. The material includes a polymerizable acrylic compound, polymerization initiator system capable of being activated by light or heat, and preferably a filler material. The resulting dental restoration has good aesthetics, mechanical strength, and margins and contacts. | 04-07-2011 |
20130213549 | ADHESIVE AND METHOD FOR BINDING ARTIFICIAL PLASTIC TEETH - The present invention is directed toward an adhesive for and a method for bonding artificial plastic teeth to a denture base. The adhesive employs a number of adhesion promoter monomers, dimers or oligomers and a cure package, as well as methyl acetate as a solvent. The method according to the invention includes exposing a plastic tooth to the adhesive and allowing the plastic to soften (not dissolve). The adhesion promoter chains infiltrate the plastic tooth matrix, such that upon curing a secure bond is formed. | 08-22-2013 |
Patent application number | Description | Published |
20120169050 | SYSTEM AND METHOD FOR OFF-HIGHWAY VEHICLE ENGINE CRANKING - Methods and systems are provided for operating an engine, the engine coupled to a traction alternator for vehicle travelling. In one example, the method includes, in an off-highway vehicle running mode of operation, supplying current from the traction alternator to a traction motor via a traction inverter to propel the vehicle, and, in a starting mode of operation, supplying stored energy from a first energy source and a secondary energy source to the traction alternator to start the engine. | 07-05-2012 |
20130154711 | METHOD, POWER UNIT, AND POWER SYSTEM HAVING GATE VOLTAGE LIMITING CIRCUIT - A power unit (e.g., inverter module) includes a housing and a switch attached to the housing. The switch may be configured to be electrically coupled to a remotely-mounted drive circuit through two or more wire leads. The power unit also includes a clamping circuit electrically coupled to terminals of the switch and in parallel with the switch. The clamping circuit may be disposed inside the housing or on an outer surface of the housing, and is configured to limit a voltage across the switch. | 06-20-2013 |
20150210158 | INTEGRATED MOUNTING AND COOLING APPARATUS, ELECTRONIC DEVICE, AND VEHICLE - An integrated mounting and cooling apparatus includes a housing body having a first mounting surface configured to receive electronic components to be cooled and a heat dissipation channel extending through the housing body under the first mounting surface. An array of cooling fins is disposed in the heat dissipation channel. The apparatus is configured to serve as a mounting surface for the electronic components, as a housing for the electronic components, and a heat-sink to cool the electronic components. | 07-30-2015 |
20150251564 | SYSTEM AND METHOD FOR CONTROLLING ENERGY USAGE - An energy management system comprises an energy management module that electrically connects an energy storage system of a vehicle with a traction link of the vehicle, the traction link being electrically connected to a traction motor. The energy management module is configured to deliver electrical power from the energy storage system to the traction link during a haul route, according to a discharge rule that is selected by a comparison of predicted performance of a plurality of discharge rules to a baseline performance of the haul route, in which electrical power is not delivered from the energy storage system to the traction link, in order to obtain fuel savings, speed excess, or a combination of fuel savings and speed excess relative to the baseline performance. | 09-10-2015 |
20160101700 | CONTROL SYSTEM AND METHOD FOR A VEHICLE - A control system for a vehicle includes an electric drive system associated with a first set of wheels. The electric drive system is configured to selectively provide electric motive power to the first set of wheels to propel the vehicle and electric retarding to slow the vehicle. The system further includes a friction brake system associated with one of the first set of wheels or a second set of wheels, a drive system control unit, and a friction brake control unit in electrical communication with the drive system control unit. The drive system control unit is configured to communicate with the friction brake control unit to control an amount of friction brake application during vehicle stops and starts on grade. | 04-14-2016 |
Patent application number | Description | Published |
20080315805 | CHOPPER CIRCUIT TOPOLOGIES FOR ADAPTING AN ELECTRICAL BRAKING SYSTEM IN A TRACTION VEHICLE - An adaptable electrical braking system for an electrical propulsion system of a traction vehicle is provided. The electrical braking system is configured to dissipate electrical energy in a plurality of resistor grids. The braking system includes a braking system assembly including a baseline chopper circuit topology. The baseline chopper circuit topology includes a first semiconductor-based circuitry in an enclosure for accommodating the first semiconductor-based circuitry. The braking system further includes a second semiconductor-based circuitry electrically coupled to the first semiconductor-based circuitry to produce a chopper including a chopper circuit topology fully contained in the enclosure. The second semiconductor-based circuitry includes a circuit topology selectable to adapt the baseline chopper circuit topology to meet distinct operational requirements to be fulfilled by the braking system. | 12-25-2008 |
20080315806 | KIT AND METHOD FOR RECONFIGURING AN ELECTRICAL BRAKING SYSTEM FOR A TRACTION VEHICLE - A kit and method for reconfiguring an electrical braking system for a traction vehicle are provided. The kit may include a braking system assembly including a chopper having a first chopper circuit topology. The first chopper circuit topology includes a first semiconductor-based circuitry having a footprint that defines at least one cavity in an enclosure for accommodating the first semiconductor-based circuitry. This enclosure constitutes the enclosure for accommodating the semiconductor-based circuitry in the chopper having electromechanical-based circuitry and semiconductor based circuitry. A second semiconductor-based circuitry is arranged in the at least one cavity in the enclosure for accommodating the first semiconductor-based circuitry. The second semiconductor-based circuitry when electrically coupled to the first semiconductor-based circuitry produces a chopper comprising a second chopper circuit topology fully contained in the enclosure. The second chopper circuit topology is operable without any electromechanical-based circuitry. | 12-25-2008 |
20090177335 | SYSTEM, METHOD, AND COMPUTER SOFTWARE CODE FOR OPTIMIZING PERFORMANCE OF A POWERED SYSTEM - A system to optimize performance of a powered system, the system including a data device configured to provide current information about current operating conditions of the powered system and/or prior information about the powered system, a controller configured to control operation of the powered system, and a processor configured to provide at least one control command to the controller for use in operating the powered system and/or user information with at least one recommended command to a user to control the powered system, wherein the at least one control command and/or user information are based at least in part on the current information and/or the prior information. A system and computer software code, stored on a computer readable media and executable with a processor, are also disclosed. | 07-09-2009 |
20090198406 | AUTOMATIC BRAKE VERIFICATION SYSTEM - A method of testing a braking device in a drivetrain of a vehicle which includes at least one tractive element coupled to a traction motor. The method includes: (a) applying the braking device to a tractive element of the vehicle; (b) using an electronic controller, causing the traction motor to apply a predetermined force to the tractive element; and (c) using the controller, monitoring the tractive element for movement while the force is being applied. A dynamic braking or “retarder” function may also be tested. A system for carrying out the method is provided. | 08-06-2009 |
20100039054 | VEHICLE, SYSTEM AND METHOD - A system includes a retarder in electrical communication through an electric link with an alternator, and a controller that compares a power measurement with an accessory load on a system during a retard event, and can reduce an electrical load on the alternator, or can remove all electrical loads from an engine, when electric power that is generated from the retarder is measured to be greater than an accessory load on the system. The system may include an alternator that provides a motor function to rotate a shaft coupled to an engine that is mechanically coupled to one or more mechanically drivable accessories. The alternator powers the mechanically drivable accessories in place of or in addition to the engine. | 02-18-2010 |
20100108419 | SYSTEM, VEHICLE, AND METHOD - A power system is provided that includes a first voltage bus, a traction motor configured to generate electrical power during a regenerative braking mode and to supply the generated electrical power to the first voltage bus, and an auxiliary system coupled to the first voltage bus. The auxiliary system comprises a second voltage bus and a power interface unit coupling the first voltage bus to the second voltage bus. The auxiliary system also comprises an energy storage device coupled to the second voltage bus and configured to store energy supplied to the second voltage bus and configured to supply stored energy to the second voltage bus and an auxiliary load configured to receive power based on power in the second voltage bus. | 05-06-2010 |
20110015807 | SYSTEM AND METHOD FOR VEHICLE PERFORMANCE CONTROL - A method is provided for controlling a drivetrain of a vehicle which includes a prime mover operatively connected to at least one tractive element. The method includes: (a) determining the vehicle's total weight; and (b) using an electronic controller carried by the vehicle, causing the prime mover to apply power to the tractive element so as to propel the vehicle, the magnitude of the power being a function of the vehicle's total weight. | 01-20-2011 |
20130066532 | AUTOMATIC BRAKE VERIFICATION SYSTEM - A method of testing a braking device in a drivetrain of a vehicle which includes at least one tractive element coupled to a traction motor. The method includes: (a) applying the braking device to a tractive element of the vehicle; (b) using an electronic controller, causing the traction motor to apply a predetermined force to the tractive element; and (c) using the controller, monitoring the tractive element for movement while the force is being applied. A dynamic braking or “retarder” function may also be tested. A system for carrying out the method is provided. | 03-14-2013 |
20140148973 | SYSTEM, METHOD, AND COMPUTER SOFTWARE CODE FOR OPTIMIZING PERFORMANCE OF A POWERED SYSTEM - A system to optimize performance of a powered system, the system including a data device configured to provide current information about current operating conditions of the powered system and/or prior information about the powered system, a controller configured to control operation of the powered system, and a processor configured to provide at least one control command to the controller for use in operating the powered system and/or user information with at least one recommended command to a user to control the powered system, wherein the at least one control command and/or user information are based at least in part on the current information and/or the prior information. A system and computer software code, stored on a computer readable media and executable with a processor, are also disclosed. | 05-29-2014 |
20140277889 | SYSTEM AND METHOD FOR VEHICLE PERFORMANCE CONTROL - A system and method are provided for controlling a drivetrain of a vehicle which includes a prime mover operatively connected to at least one tractive element. The system and method include determining the vehicle's total weight and, using an electronic controller carried by the vehicle, causing the prime mover to apply power to the tractive element so as to propel the vehicle. The magnitude of the power can be a function of the vehicle's total weight. | 09-18-2014 |
20150210283 | SYSTEM, METHOD, AND COMPUTER SOFTWARE CODE FOR OPTIMIZING PERFORMANCE OF A POWERED SYSTEM - A system to optimize performance of a powered system, the system including a data device configured to provide current information about current operating conditions of the powered system and/or prior information about the powered system, a controller configured to control operation of the powered system, and a processor configured to provide at least one control command to the controller for use in operating the powered system and/or user information with at least one recommended command to a user to control the powered system, wherein the at least one control command and/or user information are based at least in part on the current information and/or the prior information. A system and computer software code, stored on a computer readable media and executable with a processor, are also disclosed. | 07-30-2015 |
Patent application number | Description | Published |
20130239913 | Thermal Management System, Vehicle, and Associated Method - A system is provided that includes an engine coupled to an alternator; a radiator fan motor in electrical communication with the alternator, and that is mechanically decoupled from the engine; an energy storage device in electrical communication with the alternator and the radiator fan motor; and one or more traction motors in electrical communication with the energy storage device, the radiator fan motor, or both. Electricity provided through dynamic braking can power the radiator fan motor upon generation of the electricity, or it can be stored in the energy storage device for use later in powering the radiator fan motor. | 09-19-2013 |
20130248262 | HOIST SYSTEM AND METHOD - A system includes a motor coupled to an energy source and coupled to a hoist pump. During one mode of use or operation, the motor cars receive electricity from the energy source and provide mechanical power to the hoist pump. A method includes directing a motor to mechanically couple to the hoist pump, and directing electrical power to flow from an energy source to the motor, and thereby to control the speed of hoist activity. | 09-26-2013 |
20130261832 | Thermal Management System, Vehicle and Associated Method - A system includes a cooling system having a cooling fluid for cooling an engine and a radiator fan motor; a dynamic braking system configured to supply electrical energy to the fan motor during a braking event; and a controller that is operable to direct the electrical energy from the dynamic braking system to the fan motor to cool the coolant to a predetermined minimum threshold temperature. A method includes switching a vehicle thermal management system from a first mode of operation in which the coolant is maintained at a steady operating temperature to a second mode of operation in which the coolant is cooled to a minimum threshold temperature. | 10-03-2013 |
20130301326 | METHOD AND APPARATUS FOR CONTROLLING THERMAL CYCLING - A method for reducing thermal cycling of a semiconductor power switch includes obtaining a value indicative of a junction temperature of the power switch. The method also includes selecting one of several pre-determined gate drive voltages, based on the obtained value, and providing the selected gate drive voltage to a gate of the power switch. This reduces thermal cycling of a power switch relative to the thermal cycling that would be present during operation at a single gate temperature. | 11-14-2013 |
20130301755 | CONVERTER COMMUNICATION METHOD AND APPARATUS - A communication method includes detecting at a gate drive unit a change of state of a command signal that is received via a command link of the gate drive unit and initiating, responsive to the change of state of the command signal, a blanking period in which the gate drive unit will process as incoming data any further changes of state of the command signal. The method also includes receiving incoming data at the gate drive unit, by processing modulations of the command signal, within the blanking period. | 11-14-2013 |
20130308344 | POWER CONVERTER AND METHOD - A power converter apparatus includes a primary bridge having a plurality of diagonally opposed primary power elements, and a secondary bridge having a plurality of diagonally opposed secondary power elements. The primary and secondary bridges are electrically coupled by a transformer. At least one control unit is configured to phase-shift switch the primary and secondary power elements, such that one or more of the primary and secondary power elements are switched off under near-zero current conditions to reduce voltage and current stresses and commutation losses within the power converter. | 11-21-2013 |
20140023894 | ENERGY STORAGE DEVICE AND METHOD - An energy storage device that includes a housing, which includes at least one end panel that includes at least one aperture therethrough. The device further includes a battery cell housed in the housing. The battery cell includes mutually opposed first and second faces joined at their edges. The device also includes a heat sink adjacent to the battery cell and in thermal contact with the first face of the battery cell. The heat sink defines at least one cooling medium passage extending parallel to the face of the adjacent battery cell. The cooling medium passage opens onto the at least one aperture formed through the at least one end panel of the housing. | 01-23-2014 |
20140077611 | CAPACITOR BANK, LAMINATED BUS, AND POWER SUPPLY APPARATUS - A capacitor bank includes a laminated bus bar having a high potential conductive layer and a low potential conductive layer disposed in close proximity at opposing surfaces of an intervening insulation layer. The bank also includes a plurality of bus capacitors electrically connected to the laminated bus bar. The laminated bus bar and the bus capacitors having a combined inductance sufficiently low such that the bus capacitors are electrically connected effectively in parallel with the laminated bus bar. | 03-20-2014 |
20140078782 | POWER CONVERTER CONTROL SYSTEM AND METHOD - A power converter control system includes primary bridge controller that is configured to actuate a first plurality of gate drive units that switch a first plurality of power elements in a primary bridge of a power converter. The control system further includes a secondary bridge controller separate from the primary bridge controller that is configured to actuate a second plurality of gate drive units to switch a second plurality of power elements in a secondary bridge of the power converter | 03-20-2014 |
20140124170 | INTEGRATED COOLING SYSTEM AND METHOD FOR ENGINE-POWERED UNIT - The present invention relates to an integrated cooling system for a vehicle. The system includes an engine cooling loop having a first fluid configured for circulation through an engine of the vehicle and a power electronics cooling loop having a second fluid configured for circulation through at least one power electronics component of the vehicle. The engine cooling loop is fluidly isolated from, and in thermal communication with, the power electronics cooling loop. | 05-08-2014 |
20140156175 | DRIVER ALERT AND DE-RATE CONTROL SYSTEM AND METHOD - A driver alert and de-rate control system for a vehicle includes a sensor configured to monitor an engine operating condition, and a control unit in communication with the sensor. The control unit is configured to estimate a time until automatic de-rate of the engine based on the engine operating condition and to modify a performance parameter of the vehicle in dependence upon the estimated time until automatic de-rate. | 06-05-2014 |
20140184113 | BRAKING AND AUXILIARY POWER CONVERTER - An integrated power converter includes first and second auxiliary switch modules, and one or more braking switch modules. The first auxiliary switch module is mounted at a first location of a laminated bus bar, and connects a first auxiliary lead with a first power layer and a second power layer of the bus bar. The second auxiliary switch module is mounted at a second location of the bus bar, and connects a second auxiliary lead with the first and second power layers. The braking switch modules are mounted at additional locations of the bus bar, adjacent to the first and second locations. Each braking switch module connects a braking lead with one of the power layers of the bus bar, and with a dual diode module or with the other power layer of the bus bar. | 07-03-2014 |
20140185328 | APPARATUS AND METHOD FOR AVOIDING TRANSFORMER SATURATION - A controller for a power converter includes one or more controller modules operably linked to a transformer core of the power converter, to primary bridge switches of the power converter, and to secondary bridge switches of the power converter, wherein the one or more controller modules are configured to avoid saturation of the transformer core by modulating pulse widths of first electrical pulses sent to the primary bridge switches, based at least on measurements of DC components of current through primary and secondary windings adjacent the transformer core, and by modulating pulse widths of second electrical pulses sent to the secondary bridge switches, based at least on measurements of DC components of current through the primary and secondary windings. | 07-03-2014 |
20140191745 | APPARATUS AND METHOD FOR MITIGATING PERTURBATIONS IN A POWER CONVERTER - A power converter includes a plurality of switches that interconnect first and second input terminals of the power converter with first and second output terminals of the power converter. The switches are switched to convert power from the input terminals to the output terminals. During the switching, voltage spikes are mitigated by a first RLC branch connected from the first input terminal to the first output terminal and by a second RLC branch connected from the second input terminal to the second output terminal. | 07-10-2014 |
20140354042 | FAILURE PROTECTION FOR A POWER DELIVERY SYSTEM - A power delivery system includes a bus bar and a housing coupled to the bus bar. A semiconductor power device is enclosed within the housing. The housing comprises an outlet configured to direct failure material of the power semiconductor device away from any remaining components connected to the bus bar. In another aspect, the power delivery system additionally or alternatively comprises two bus bars. A first of the two bus bars has a first landing, a riser, and a second landing, which is parallel to the first landing and in effect spatially offset from the first landing. A second of the two bus bars is attached to the second landing of the first bus bar, such that the second bus bar is parallel to but offset from the first landing of the bus bar. | 12-04-2014 |
20150053173 | VEHICLE TEMPERATURE REGULATION SYSTEM AND METHOD - A temperature regulation system for a vehicle includes a drive system configured to be coupled to an engine of the vehicle. The drive system is configured to convert power produced by the engine into electrical power for use by at least one traction motor of the vehicle. The system further includes a control unit for controlling the engine and drive system. The control unit is configured to automatically regulate a temperature of a vehicle component in dependence upon a detected reference temperature. | 02-26-2015 |
20150081150 | SYSTEM AND METHOD FOR CONTROLLING A VEHICLE - A control system for a vehicle comprises a control unit configured to be electrically coupled to a drive system of the vehicle. The drive system includes at least one traction motor for providing motive power to the vehicle. The control unit is configured to control a torque output of the traction motor to hold zero speed or near zero speed of the vehicle on a grade without knowing information, in at least one mode of operation, about the grade and/or a load of the vehicle, and without a service brake of the vehicle being activated. | 03-19-2015 |
20160101699 | SYSTEM AND METHOD FOR REDUCING FUEL CONSUMPTION IN A VEHICLE - A drive system includes an engine, an alternator coupled to the engine, the alternator being configured to power at least one auxiliary load, a traction motor system operatively coupled to drive wheels of the vehicle, the traction motor system being configured for receiving primary electrical power from the alternator and for propelling the vehicle in response to the primary electrical power, and a motor electrically connected to the traction motor system and mechanically coupled to the engine. The motor is configured to receive electrical power from the traction motor system in a dynamic braking mode of operation of the traction motor system and to communicate power to the engine during the dynamic braking mode. | 04-14-2016 |
Patent application number | Description | Published |
20080311553 | Perfusion and/or preservation solution for organs - The present invention relates to a solution for preservation, perfusion, and/or reperfusion of an organ, especially the heart, for transplantation. The solution contains peptide inhibitor(s) of protein kinase C βII (PKC βII) and/or of protein kinase C ζ (PKC ζ) and/or peptide activator(s) of protein kinase C δ (PKCδ). Methods for using the inventive solution are also disclosed, including methods for preserving an organ for transplantation, for protecting an ischemic organ from damage, for attenuating organ dysfunction after ischemia, for maintaining nitric oxide release and/or inhibiting superoxide release in an ischemic organ, and for protecting an organ from damage when isolated from the circulatory system. | 12-18-2008 |
20120141973 | PERFUSION AND/OR PRESERVATION SOLUTION FOR ORGANS - The present invention relates to a solution for preservation, perfusion, and/or reperfusion of an organ, especially the heart, for transplantation. The solution contains peptide inhibitor(s) of protein kinase C βII (PKC βII) and/or of protein kinase C ζ (PKC ζ) and/or peptide activator(s) of protein kinase C δ (PKCδ). Methods for using the inventive solution are also disclosed, including methods for preserving an organ for transplantation, for protecting an ischemic organ from damage, for attenuating organ dysfunction after ischemia, for maintaining nitric oxide release and/or inhibiting superoxide release in an ischemic organ, and for protecting an organ from damage when isolated from the circulatory system. | 06-07-2012 |
20140220549 | ORGAN PRESERVATION AND/OR PERFUSION - The present invention relates to a solution for preservation, perfusion, and/or reperfusion of an organ, especially the heart, for transplantation. The solution contains peptide inhibitor(s) of protein kinase C ε (PKC ε). Methods for using the inventive solution are also disclosed, including methods for preserving an organ for transplantation, for protecting an ischemic organ from damage, for attenuating organ dysfunction after ischemia, for maintaining nitric oxide release and/or inhibiting superoxide release in an ischemic organ, and for protecting an organ from damage when isolated from the circulatory system. | 08-07-2014 |
Patent application number | Description | Published |
20110307059 | METHOD OF TENDON REPAIR WITH AMNION AND CHORION CONSTRUCTS - It is described a construct for use in surgical repair of tendon. The construct contains at least one layer of human amnion and chorion tissues and is generally cylindrical with a C-shaped cross-section to allow for ease of implantation over the tendon. Methods for preparing the construct is described. In addition, an improved method for surgical repair of a damaged or diseased tendon using the construct is also described. The improved method reduces adhesions, scar formation, inflammation and risk of post-operative infection. | 12-15-2011 |
20120010708 | AMNION AND CHORION REPLACEMENT COVER AND USES THEREOF IN SURGICAL REPAIR OF MUSCLES - Improved methods for a surgical repair of a muscle are described. The improvement includes covering a damaged site of muscle with at least one of an amniotic fluid and a replacement cover for muscle sheath prior to wound closing during the surgery. The replacement cover contains at least one layer of human amnion and chorion tissues and is adapted to a shape appropriate for enclosing the muscle. The methods reduce inflammation, inhibit fibrosis, scarring, fibroblast proliferation and post-operative infection, while also promote more rapid healing and smooth gliding of the affected muscle against adjacent structures. Related replacement covers, kits and methods of preparation are also described. | 01-12-2012 |
20120010727 | AMNION AND CHORION CONSTRUCTS AND USES THEREOF IN SPORT INJURY SURGERIES - Improved methods for sport injury surgeries are described. The improvement includes covering a damaged site of fascia with at least one of an amniotic fluid and a construct for use in surgical repair of the sport injury prior to wound closing. The construct contains an allograft comprising at least one layer of human amnion and chorion tissues and the construct has a size and shape suitable for covering the damaged site of fascia. The method improves fascial membrane repair, reduces complications and recovery time of sport injury surgeries. | 01-12-2012 |
20120020933 | METHOD OF NERVE REPAIR WITH AMNION AND CHORION CONSTRUCTS - Improved methods for the surgical repair of a damaged or severed nerve are described. The improvement includes covering the surgically repaired nerve or a damaged neurilemma with at least one of an amniotic fluid and a construct, or replacing the damaged neurilemma with the construct prior to wound closing during the surgery. The construct contains an allograft having at least one layer of amnion and chorion tissues, and a shape adapted for enclosing a damaged or severed nerve or for covering or replacing the damaged neurilemma during the surgical repair. The products and methods improve the performance of the nerve surgery, e.g., by reducing inflammation, inhibiting fibrosis, scarring, fibroblast proliferation, post-operative infection while also promoting more rapid healing of damaged or traumatized nerve structures. | 01-26-2012 |
20120035743 | AMNION AND CHORION CONSTRUCTS AND USES THEREOF IN MINIMALLY INVASIVE SURGERIES - A construct for use in a minimally invasive surgery is described. The construct contains an allograft having at least one layer of human amnion and chorion tissues, and is adapted for insertion into a small incision or a cannula employed in the minimally invasive surgery for access to the surgical site. The allograft has a shape appropriate for covering the surgical site. Methods of preparing the construct and using it in a minimally invasive surgery are also described. The products and methods improve the performance of the minimally invasive surgery, e.g., by reducing adhesions, scar formation while also reducing inflammation and risk of post-operative infection. | 02-09-2012 |
20120035744 | AMNION AND CHORION CONSTRUCTS AND USES THEREOF IN JOINT REPAIR - A construct for use in a surgical repair of a damaged or inflamed joint is described. The construct contains an allograft having at least one layer of human amnion and chorion tissues, and is adapted for enclosing a damaged or inflamed joint or for covering or replacing a damaged or inflamed joint sheath during the surgical repair. Methods of preparing the construct and using it in a surgical repair of a damaged or inflamed joint are also described. The products and methods improve the performance of the joint surgery, e.g., by reducing inflammation, inhibiting fibrosis, scarring, fibroblast proliferation and post-operative infection while also promoting more rapid healing of damaged or traumatized joints. | 02-09-2012 |
20130209524 | METHOD OF USING AMNION ALLOGRAFT IN HEART TRANSPLANT SURGERY - Improved methods for heart transplant are described. The methods utilize an allograft comprising a layer of amnion to improve the performance and reduce complications of the heart transplant surgery and the allograft has a pre-made size and shape suitable for the application. | 08-15-2013 |
20130211502 | METHOD OF USING AMNION ALLOGRAFT IN CORONARY ARTERY BYPASS GRAFTING - Improved methods for coronary artery bypass grafting surgeries are described. The methods utilize an allograft comprising a layer of amnion to improve the performance and reduce complications of the surgeries and the allograft has a pre-made size and shape suitable for the application. | 08-15-2013 |
20130211503 | METHOD OF USING AMNION ALLOGRAFT IN CONGENITAL HEART DISEASE SURGERY - Improved methods, compositions and kits for congenital heart disease surgeries are described. The methods utilize amniotic fluid and/or an allograft comprising a layer of amnion to improve the performance and reduce complications of the surgeries and the allograft has a pre-made size and shape suitable for the application. | 08-15-2013 |
20130211504 | METHOD OF USING AMNION ALLOGRAFT IN HEART VALVE REPAIR SURGERY - Improved methods for heart valve repair surgery are described. The methods utilize an allograft comprising a layer of amnion to improve the performance and reduce complications of heart valve repair surgery and the allograft has a pre-made size and shape suitable for the application. | 08-15-2013 |
20130211511 | METHOD OF USING AMNION ALLOGRAFT IN HEART VALVE REPLACEMENT SURGERY - Improved methods for heart valve replacement surgery are described. The methods utilize an allograft comprising a layer of amnion to improve the performance and reduce complications of heart valve replacement surgery and the allograft has a pre-made size and shape suitable for the application. | 08-15-2013 |
20130236506 | AMNION AND CHORION CONSTRUCTS AND USES THEREOF IN OB-GYN SURGERY - A construct for use in an OB/GYN surgery is described. The construct contains an allograft having at least one layer of human amnion and chorion tissues, and has a size and shape appropriate for covering an incision or a surgical site resulting from the surgery. Methods of preparing the construct and using it in an OB/GYN surgery are also described. The products and methods improve the performance of the OB/GYN surgery, e.g., by reducing adhesions, scar formation while also reducing inflammation and risk of post-operative infection. | 09-12-2013 |
20130238100 | AMNION AND CHORION CONSTRUCTS AND USES THEREOF IN ABDOMINAL SURGERY - A construct for use in an abdominal surgery is described. The construct contains an allograft having at least one layer of human amnion and chorion tissues, and has a size and shape appropriate for covering an incision or a surgical site resulting from the surgery. Methods of preparing the construct and using it in an abdominal surgery are also described. The products and methods improve the performance of the abdominal surgery, e.g., by reducing adhesions, scar formation while also reducing inflammation and risk of post-operative infection. | 09-12-2013 |
20130289468 | LAPAROSCOPIC APPLICATOR AND USES THEREOF - An applicator for use in a laparoscopic surgery is described. The applicator allows the effective delivery of a surgical dressing, such as an allograft having at least one layer of human amnion and chorion tissues, to the surgical site, to thereby improve the performance of the surgery, e.g., by reducing adhesions, scar formation while also reducing inflammation and risk of post-operative infection. | 10-31-2013 |
20130289724 | AMNION AND CHORION WOUND DRESSING AND USES THEREOF - An improved wound dressing is described. The wound dressing contains an allograft having at least one layer of human amnion and chorion tissues that has a size and shape appropriate for covering a wound, a base sheet for securing the allograft over the wound, and optionally a support layer to protect the allograft. Methods of preparing the wound dressing and using it in wound healing are also described. The products and methods improve the performance of the wound healing, e.g., by accelerating wound healing, reducing scar formation, inflammation and risk of infection. | 10-31-2013 |
20140277579 | USES OF AMNION CONSTRUCTS IN MINIMALLY INVASIVE SURGERIES - A construct for use in a minimally invasive surgery is described. The construct contains an allograft having at least one layer of human amnion and chorion tissues, and is adapted for insertion into a small incision or a cannula employed in the minimally invasive surgery for access to the surgical site. The allograft has a shape appropriate for covering the surgical site. Methods of preparing the construct and using it in a minimally invasive surgery are also described. The products and methods improve the performance of the minimally invasive surgery, e.g., by reducing adhesions, scar formation while also reducing inflammation and risk of post-operative infection. | 09-18-2014 |
Patent application number | Description | Published |
20090100802 | VACUUM PACKAGE SYSTEM - A vacuum packaging system for transporting a plurality of medical containers includes a plurality of medical containers each having a head side and a base side and a tray that receives and supports the medical containers. The tray includes opposing first and second sidewalls, opposing front and rear walls and a bottom floor. The walls extend generally vertically from the floor of the tray. At least one platform generally extends parallel to the floor of the tray. An air impervious flexible film defines an internal cavity. The air impervious flexible film completely surrounds the tray and the medical containers and the internal cavity is evacuated to and maintained at a predetermined vacuum level below atmospheric pressure. One of the head side and the base side of each medical container contacts a top surface of at least one platform when the medical containers are positioned in the tray. | 04-23-2009 |
20090288977 | Vacuum Package System - A vacuum packaging system for transporting a plurality of medical containers includes a plurality of medical a tray that receives and supports the medical containers. The tray includes opposing first and second side walls, opposing side and rear walls and a bottom floor. The walls extend generally perpendicularly from the bottom floor of the tray to a top edge thereof. A nesting plate is removably mountable in the tray and includes a plurality of generally cylindrical sleeves each receiving one of the plurality of medical containers. A support surface within the tray generally extends parallel to and spaced a predetermined distance from the bottom floor of the tray and receives and supports the nesting plate. An air impervious flexible film defines an internal cavity and completely surrounds the tray and the medical containers. The internal cavity is evacuated to and maintained at a predetermined vacuum level below atmospheric pressure. | 11-26-2009 |
20100012546 | Medical Container - The present invention relates to a medical container useful upon transportation of plural syringe barrels. The medical container includes at least a container main body and a holding member arranged inside the container main body. The holding member is provided at least with a plurality of cylindrical holding portions for holding syringe barrels. The container main body has at least a peripheral rim arranged on and along an outer periphery of an opening and a shoulder-shaped portion arranged on an inner wall of the container to arrange the holding member. The shoulder-shaped portion has at least three ribs for supporting the holding member, and has a structure that enables to arrange via the ribs the holding member in a horizontal position relative to a bottom wall of the container main body. According to the present invention, there is provided a medical container of a construction that can be promptly brought into a sterilized state by various methods, can be readily brought into a state capable of maintaining the sterilized state, and during transportation, can fixedly secure, without rattling, syringe barrels held upright by holders. | 01-21-2010 |
20120118903 | APPARATUS AND METHOD FOR FILLING FLANGELESS CONTAINERS - A finger grip for a flangeless container, the finger grip having a skirt removably attachable to an open end portion of the container and a lip that extends radially outwardly from the skirt. The flangeless container is fillable by capping the container using a cap element to attach the finger grip to the container; installing the container in a container support assembly including a tray having a plurality of wells; filling the container; inserting a piston into the container; and removing the finger grip. Each well has a depth less than a predetermined length of the container, a lower portion of each well having a first cross-sectional shape similar to but greater than the cross-sectional shape of the flangeless container, an upper portion of each well having a second cross-sectional shape similar to but greater than the first cross-sectional shape. | 05-17-2012 |
Patent application number | Description | Published |
20090060930 | Enhanced immunogenicity of tumor associated antigens by addition of alphaGal epitopes - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epitopes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 03-05-2009 |
20120003251 | ENHANCED IMMUNOGENICITY OF TUMOR ASSOCIATED ANTIGENS BY ADDITION OF ALPHAGAL EPITOPES - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epi topes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 01-05-2012 |
20130164318 | ENHANCED IMMUNOGENICITY OF TUMOR ASSOCIATED ANTIGENS BY ADDITION OF ALPHAGAL EPITOPES - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epitopes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 06-27-2013 |
20130164319 | ENHANCED IMMUNOGENICITY OF TUMOR ASSOCIATED ANTIGENS BY ADDITION OF ALPHAGAL EPITOPES - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epitopes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 06-27-2013 |
20130178613 | ENHANCED IMMUNOGENICITY OF TUMOR ASSOCIATED ANTIGENS BY ADDITION OF ALPHAGAL EPITOPES - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epitopes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 07-11-2013 |