Yoon, MA
Christopher Yoon, Cambridge, MA US
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20150050717 | BACTERIOPHAGES EXPRESSING ANTIMICROBIAL PEPTIDES AND USES THEREOF - The present invention is generally related to engineered bacteriophages expressing antimicrobial peptides or lytic enzymes or fragments thereof for targeting a broad spectrum of bacterial hosts, and for the long-term suppression of bacterial phage resistance for reducing bacterial infections. In some embodiments, bacteriophages express antimicrobial peptides or antimicrobial polypeptides (e.g. phage lytic enzymes) which are secreted from the host bacteria, or alternatively released upon lysis of the bacterial host cell. Aspects of the present invention also relate to the use of the engineered bacteriophages for the reduction of bacterial infections, both in a subject or for bioremediation purposes, in clinical settings and wound healing. | 02-19-2015 |
Clifford Hyunsuk Yoon, Boston, MA US
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20080248475 | Methods and Compositions for Modulating Gluconeogenesis Using PGC-1 - The invention provides novel methods and compositions for modulating gluconeogenesis through modulation of PGC-1 activity or expression. Also provided are methods for identifying compounds that modulate gluconeogenesis through modulation of PGC-1 activity or expression, as well as methods for identifying compounds that modulate the interaction of PGC-1 with PGC-1 target molecules. Further provided are methods for treating disorders characterized by aberrant gluconeogenesis. | 10-09-2008 |
Insun Yoon, Belmont, MA US
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20110305761 | POLYMERSOMES, COLLOIDOSOMES, LIPOSOMES, AND OTHER SPECIES ASSOCIATED WITH FLUIDIC DROPLETS - The present invention relates generally to vesicles such as liposomes, colloidosomes, and polymersomes, as well as techniques for making and using such vesicles. In some cases, the vesicles may be at least partially biocompatible and/or biodegradable. The vesicles may be formed, according to one aspect, by forming a multiple emulsion comprising a first droplet surrounded by a second droplet, which in turn is surrounded by a third fluid, where the second droplet comprises lipids and/or polymers, and removing fluid from the second droplet, e.g., through evaporation or diffusion, until a vesicle is formed. In certain aspects, the size of the vesicle may be controlled, e.g., through osmolarity, and in certain embodiments, the vesicle may be ruptured through a change in osmolarity. In some cases, the vesicle may contain other species, such as fluorescent molecules, microparticles, pharmaceutical agents, etc., which may be released upon rupture. Yet other aspects of the invention are generally directed to methods of making such vesicles, kits involving such vesicles, or the like. | 12-15-2011 |
20140065234 | POLYMERSOMES, LIPOSOMES, AND OTHER SPECIES ASSOCIATED WITH FLUIDIC DROPLETS - The present invention relates generally to vesicles such as liposomes, colloidosomes, and polymersomes, as well as techniques for making and using such vesicles. In some cases, the vesicles may be at least partially biocompatible and/or biodegradable. The vesicles may be formed, according to one aspect, by forming a multiple emulsion comprising a first droplet surrounded by a second droplet, which in turn is surrounded by a third fluid, where the second droplet comprises lipids and/or polymers, and removing fluid from the second droplet, e.g., through evaporation or diffusion, until a vesicle is formed. In certain aspects, the size of the vesicle may be controlled, e.g., through osmolarity, and in certain embodiments, the vesicle may be ruptured through a change in osmolarity. In some cases, the vesicle may contain other species, such as fluorescent molecules, microparticles, pharmaceutical agents, etc., which may be released upon rupture. Yet other aspects of the invention are generally directed to methods of making such vesicles, kits involving such vesicles, or the like. | 03-06-2014 |
Joonsung Yoon, Amherst, MA US
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20080268239 | REINFORCED POLYMERIC MATERIALS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a low molecular weight compound that exists in the form of a second crystalline phase; wherein the second crystalline phase is dispersed within the first organic polymer phase. Disclosed herein too is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a second phase that comprises a crystalline organic polymer, wherein the crystalline organic polymer has a different molecular structure from the first organic polymer; wherein the second phase is not covalently bonded to the first organic polymer phase and wherein the second phase has an average particle size of about 1 to about 20 micrometers. | 10-30-2008 |
20130253140 | REINFORCED POLYMETRIC MATERIALS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a low molecular weight compound that exists in the form of a second crystalline phase; wherein the second crystalline phase is dispersed within the first organic polymer phase. Disclosed herein too is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a second phase that comprises a crystalline organic polymer, wherein the crystalline organic polymer has a different molecular structure from the first organic polymer; wherein the second phase is not covalently bonded to the first organic polymer phase and wherein the second phase has an average particle size of about 1 to about 20 micrometers. | 09-26-2013 |
Jung U. Yoon, Belmont, MA US
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20100025787 | System and method for providing a high frequency response silicon photodetector - A Silicon photodetector contains an insulating substrate having a top surface and a bottom surface. A Silicon layer is located on the top surface of the insulating substrate, where the Silicon layer contains a center region, the center region being larger in thickness than the rest of the Silicon layer. A top Silicon dioxide layer is located on a top surface of the center region. A left wing of the center region and a right wing of the center region are doped. The Silicon photodetector also has an active region located within the center region, where the active region contains a tailored crystal defect-impurity combination and Oxygen atoms. | 02-04-2010 |
Myung-Han Yoon, Cambridge, MA US
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20080224127 | Gate dielectric structures, organic semiconductors, thin film transistors and related methods - Gate dielectric structures comprising an organic polymeric component, and organic semiconductor components, as can be used to fabricate thin film transistor devices. | 09-18-2008 |
20100019237 | Siloxane-Polymer Dielectric Compositions and Related Organic Field-Effect Transistors - Dielectric compositions comprising siloxane and polymeric components, as can be used in a range of transistor and related device configurations. | 01-28-2010 |
20120261655 | Inorganic-Organic Hybrid Thin-Film Transistors Using Inorganic Semiconducting Films - Inorganic semiconducting compounds, composites and compositions thereof, and related device structures. | 10-18-2012 |
Sang-Young Yoon, Lexington, MA US
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20100136411 | Prismatic Cell With Outer Electrode Layers Coated On A Single Side - Embodiments of the present invention provide an electrochemical cell including a stack of electrode layers and separator layers. The electrode layers include anode layers and cathode layers disposed in an alternating manner and separated by the separator layers. The two outer electrode layers of the stack are of the same type and are coated with an active material on an inward-facing surface only. The electrochemical cell may include two or more insulating layers disposed at the two ends of the electrode stack, and a pouch enclosing the electrode stack and the insulating layers. | 06-03-2010 |
20100192362 | Split Charge Forming Process for Battery - A split formation method of forming an electrochemical cell includes providing the electrochemical chemical cell with an electrolyte for activation of the cell. A wait period is then conducted without a charge being applied. Thereafter, the cell is initially charged to an amount falling into a predetermined state of charge (SOC) range. After the charge is applied, the cell is stored for an extended period of time in a controlled temperature environment. A degassing procedure may be performed after storage to provide a uniform distance between the electrodes. Upon completion of the storage period a further charge is applied to cell that is higher than the initial charge. The cell is then allowed to stabilize for a predetermined amount of time at a set temperature. | 08-05-2010 |
Sang-Young Yoon, Bedford, MA US
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20130040203 | ANODE MATERIAL - The present disclosure relates to anode materials having high surface areas and improved cycle performance made by surface treatments of spheroidized graphite powders. The surface treatments provide a high surface area protective coating over the spheroidized graphite powder. The anodes made according to the disclosed embodiments have improved cycle life and long term high temperature storage performance. In the disclosed embodiments, a spheroidized graphite powder is coated with a high surface area protective coating. The high surface area protective coating improves the performance and durability of an anode made from disclosed 200 material. The high surface area protective coating can include polymers, metal compounds and/or hard carbon. Further, in some embodiments, a protective coating, that may or may not have a high surface area but does have increased durability, can be formed by heat treating the spheroidized graphite in oxidizing or inert atmospheres. | 02-14-2013 |
20140065487 | FORMING GAS TREATMENT OF LITHIUM ION BATTERY ANODE GRAPHITE POWDERS - The invention provides a method of making a battery anode in which a quantity of graphite powder is provided. The temperature of the graphite powder is raised from a starting temperature to a first temperature between 1000 and 2000° C. during a first heating period. The graphite powder is then cooled to a final temperature during a cool down period. The graphite powder is contacted with a forming gas during at least one of the first heating period and the cool down period. The forming gas includes H | 03-06-2014 |
20140138591 | BLENDED CATHODE MATERIALS - A positive electroactive material is described, including: a lithium iron manganese phosphate compound having a composition of Li | 05-22-2014 |
20150093617 | LITHIUM ION PRISMATIC CELL COMPRISING MULTIPLE JELLY ROLLS WITH ADDITIONAL MATERIAL BETWEEN JELLY ROLLS - Techniques disclosed herein include systems and methods that improve the speed of jelly roll assembly for large format and high capacity cells as compared to a stack-folding production method. In one embodiment, a higher speed winding process is achieved, and, in addition, a higher capacity and energy can be achieved by adding at least one (additional) cathode layer between the jelly roll. Such an addition minimizes the loss of use of an anode outer layer. | 04-02-2015 |
Sung-Hwan Yoon, Dracut, MA US
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20110123711 | METHODS FOR FORMING METAL-POLYMER HYBRID TOOLING FOR FORMING PARTS HAVING MICRO FEATURES - A method for forming metal-polymer hybrid tooling includes patterning a surface of a member such as a silicon wafer, stainless steel, nickel or nickel alloy, engaging a polymer layer with the patterned features of the surface of the silicon wafer to form the polymer layer having a reverse of the patterned surface the silicon wafer, removing the patterned polymer layer to expose a patterned polymer layer surface, depositing a metallic layer on the patterned polymer layer surface, and wherein the deposited metallic layer on the patterned polymer layer is operable to form parts with features having a width dimension between about 0.01 microns and about 100 microns and a height dimension of between about 0.01 micron and about 800 microns (e.g., up to aspect ratio of 8). | 05-26-2011 |
Taeyoung Yoon, Cambridge, MA US
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20110092505 | ORGANIC COMPOUNDS - The present invention provides novel organic compounds of Formula I: methods of use, and pharmaceutical compositions thereof. | 04-21-2011 |
Taeyoung Yoon, Newton, MA US
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20110046133 | ORGANIC COMPOUNDS - The present invention provides compounds of the following structure; | 02-24-2011 |
20110160187 | 3-aryl-5,6-disubstituted pyridazines - The present invention provides compounds of Formula (I) or (II) salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions. | 06-30-2011 |
20120142685 | ORGANIC COMPOUNDS - The present invention provides a compound formula I: (formula I) said compound is inhibitor of selective subset of kinases belonging to the AGC or calmodulin kinase family, such as for example MARK1/2/3, PKD-1/2/3, PKN-1/2, CDK-9, CaMKII, ROCK-I/II, inhibitors of histone deacetylase (HDAC) phosphorylation, or inhibitors of other kinases. Finally, the present invention also provides a pharmaceutical composition. | 06-07-2012 |
Won Yoon, Boston, MA US
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20100228963 | METHODS OF PLACING ADVERTISMENTS, INTERSTITIALS AND TOOLBARS IN A WEB BROWSER - The present invention provides methods and systems that can render INE content to a web browser. Various methods and approaches are disclosed that when implemented would enable an INE to place some of INE's contents in a web browser of a user. The INE content can be in the form of a tool bar or interstitial content. The invention can provide one or more of the following advantages: a) provide an opportunity for INE to conduct e-commerce, b) enable an INE to develop alternate revenue generation model, and c) enable an INE or it's related entities to participate in e-commerce and advertising. | 09-09-2010 |
Wonseok Yoon, Burlington, MA US
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20140051007 | BIPOLAR PLATES FOR USE IN ELECTROCHEMICAL CELLS - The present disclosure is directed towards the design of electrochemical cells for use in high pressure or high differential pressure operations. The electrochemical cells of the present disclosure have non-circular external pressure boundaries, i.e., the cells have non-circular profiles. In such cells, the internal fluid pressure during operation is balanced by the axial tensile forces developed in the bipolar plates, which prevent the external pressure boundaries of the cells from flexing or deforming. That is, the bipolar plates are configured to function as tension members during operation of the cells. To function as an effective tension member, the thickness of a particular bipolar plate is determined based on the yield strength of the material selected for fabricating the bipolar plate, the internal fluid pressure in the flow structure adjacent to the bipolar plate, and the thickness of the adjacent flow structure. | 02-20-2014 |
20150024298 | SYSTEM AND METHOD FOR TUNING AN ELECTROCHEMICAL CELL STACK - The present disclosure is directed to a method for tuning the performance of at least one electrochemical cell of an electrochemical cell stack. The method includes supplying power to an electrochemical cell stack. The electrochemical cell stack includes a plurality of electrochemical cells. The method further includes monitoring a parameter of at least one electrochemical cell and determining if an electrochemical cell becomes impaired. The method also includes diverting a fraction of the current flow from the impaired electrochemical cell during operation of the electrochemical cell stack. | 01-22-2015 |
Young Gyu Yoon, Cambridge, MA US
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20160091705 | Methods and apparatus for stretched light field microscope - The information budget of a light field microscope is increased by increasing the field of view and image circle diameter of the microscope, while keeping the ratio of overall magnification of the microscope to the numerical aperture of the microscope unchanged. Alternatively, the information budget is increased by increasing the field of view and image circle diameter of the microscope by a first factor, while increasing the ratio of overall magnification of the microscope to the numerical aperture of the microscope by a smaller, second factor. In some cases, an infinity-corrected light field microscope has an overall magnification that is greater than the nominal magnification of the objective lens. | 03-31-2016 |