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Yohannes, US

Asheber Yohannes, Littleton, CO US

Patent application numberDescriptionPublished
20140256201FIBER REINFORCED COMPOSITES MADE WITH COUPLING-ACTIVATOR TREATED FIBERS AND ACTIVATOR CONTAINING REACTIVE RESIN - This invention relates to a process of making a fiber-reinforced composite. Glass fibers may be provided. These glass fibers may be treated with a sizing composition that has a coupling-activator compound with the formula: S—X-(A)09-11-2014
20140364025FIBER-REINFORCED COMPOSITE ARTICLES AND METHODS OF MAKING THEM - Methods of making prepregs are described. The methods include the steps of forming a fiber-containing substrate, and contacting the fiber-containing substrate with a resin mixture. The resin mixture may include polymer particles mixed in a liquid medium, and the polymer particles may be coated on the fiber-containing substrate to form a coated substrate. The liquid medium may be removed from the coated substrate to form the prepreg. The prepregs may be used to make fiber-reinforced articles.12-11-2014
20150144253FIBER-CONTAINING PREPREGS AND METHODS AND SYSTEMS OF MAKING - Methods of making a fiber-containing prepregs may include drawing unsized fibers from a batch of molten glass. The method may also include applying a sizing composition to the unsized fibers to form a plurality of sized fibers, where the sizing composition includes a first polymerization agent for polymerizing caprolactam. The method may further include weaving the plurality of sized fibers into a fabric. Another step may include melting a reactive resin composition to form a melted reactive resin composition, where the reactive resin composition may include caprolactam. The melted reactive resin composition may be applied to the fabric. The method may further include heating the fabric and the melted reactive resin composition to a polymerization temperature, where the caprolactam polymerizes to form a fiber-resin amalgam including a polyamide. Another step may be to form the fiber-resin amalgam into the fiber-containing prepreg.05-28-2015
20150145165FIBER-CONTAINING PREPREGS AND METHODS AND SYSTEMS OF MAKING - Methods of making fiber-containing prepregs are described. The methods may include the steps of providing a plurality of fibers, and applying a reactive resin composition to the plurality of fibers to make a mixture of the plurality of fibers and the resin composition. The reactive resin composition may include at least one of monomers and oligomers capable of polymerizing into a polymerized resin matrix. The mixture may be heated to a polymerization temperature where the monomers, oligomers, or both polymerize to form a fiber-resin amalgam that includes the polymerized resin matrix. The fiber-resin amalgam may be formed into the fiber-containing prepreg. Also described are methods of forming a fiber-reinforced composite that includes the prepreg.05-28-2015
20150148485FIBER-REINFORCED COMPOSITES MADE WITH REACTIVE RESIN COMPOSITIONS AND FIBERS - Methods of making fiber-resin compositions are described. The method may include the providing of a reactive resin composition to an extruder, where the reactive resin composition may include monomers, oligomers, or both, that are capable of polymerizing into a thermoplastic resin. The method may further include combining the reactive resin composition with a plurality of reactive fibers that are also supplied to the extruder. The plurality of reactive fibers may be sized with at least one polymerization agent and/or coupling agent. The fiber-resin composition may be extruded from the extruder, where the composition includes a thermoplastic resin in contact with the plurality of fibers that is formed by the polymerization of the monomers and/or oligomers of the reactive resin composition. Also described are methods of making fiber-reinforced composite articles from the fiber-resin composition.05-28-2015
20150148498FIBER-REINFORCED COMPOSITES MADE WITH THERMOPLASTIC RESIN COMPOSITIONS AND REACTIVE COUPLING FIBERS - Methods of making fiber-resin compositions are described. The methods may include the providing of a thermoplastic resin to an extruder, where the thermoplastic resin may include at least one reactive moiety capable of forming a covalent bond with a coupling agent on a plurality of reactive fibers. The methods may further include combining the thermoplastic resin with the plurality of reactive fibers also supplied to the extruder. The reactive fibers are sized with the coupling agent that reacts with the thermoplastic resin to form the fiber-resin composition, which may be extruded from the extruder. Methods of making fiber-reinforced composite articles from the fiber-resin composition are also described.05-28-2015
20160024266FIBER-CONTAINING PREPREGS AND METHODS AND SYSTEMS OF MAKING - Methods of making a fiber-containing prepregs may include drawing unsized fibers from a batch of molten glass. The method may also include applying a sizing composition to the unsized fibers to form a plurality of sized fibers, where the sizing composition includes a first polymerization agent for polymerizing caprolactam. The method may further include weaving the plurality of sized fibers into a fabric. Another step may include melting a reactive resin composition to form a melted reactive resin composition, where the reactive resin composition may include caprolactam. The melted reactive resin composition may be applied to the fabric. The method may further include heating the fabric and the melted reactive resin composition to a polymerization temperature, where the caprolactam polymerizes to form a fiber-resin amalgam including a polyamide. Another step may be to form the fiber-resin amalgam into the fiber-containing prepreg.01-28-2016
20160102182FIBER-REINFORCED COMPOSITE ARTICLES AND METHODS OF MAKING THEM - Methods of making a prepreg are described. The methods include the steps of forming a fiber-containing substrate, and contacting the fiber-containing substrate with a resin mixture. The resin mixture may include particles of monomers or oligomers mixed in a liquid medium, and the particles may be coated on the fiber-containing substrate to form a coated substrate. The liquid medium may be removed from the coated substrate to form the prepreg. The prepregs may be used to make fiber-reinforced articles.04-14-2016

Patent applications by Asheber Yohannes, Littleton, CO US

Asheber Yohannes, Littlelon, CO US

Patent application numberDescriptionPublished
20160046107SIZED GLASS FIBERS FOR FIBER-CONTAINING COMPOSITE ARTICLES AND METHODS OF MAKING THEM - Methods of making prepregs are described. The methods include the steps of forming a fiber-containing substrate, and contacting the fiber-containing substrate with a resin mixture. The resin mixture may include polymer particles mixed in a liquid medium, and the polymer particles may be coated on the fiber-containing substrate to form a coated substrate. The liquid medium may be removed from the coated substrate to form the prepreg. The prepregs may be used to make fiber-reinforced articles.02-18-2016

Dan Yohannes, Cambridge, MA US

Patent application numberDescriptionPublished
20090130097Quinazolinone Compounds and Methods of Use Thereof - The present invention relates to quinazolinone compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising the quinazolinone compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a quinazolinone compound of the present invention05-21-2009
20110217300Quinazolinone Compounds and Methods of Use Thereof - The present invention relates to quinazolinone compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising the quinazolinone compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a quinazolinone compound of the present invention09-08-2011

Daniel Yohannes, Winston-Salem, NC US

Patent application numberDescriptionPublished
200900935121, 2, 3, 3A, 8, 8A-HEXAHYDRO-2, 7A-DIADA-CYCLOPENTA[A]INDEN-7-ONE DERIVATIVES WHICH BIND TO NEURONAL NICOTINIC ACETYLCHOLINE SPECIFIC RECEPTOR SITES AND ARE USEFUL IN MODULATING CHOLINERGIC FUNCTION AND IN THE TREATMENT OF ADDICTIVE DISORDERS - The present invention relates to novel fused bicyclicpyrrolidine pyridone compounds of the formula (I) wherein R, R04-09-2009
20110257168DERIVATIVES OF OXABISPIDINE AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS - The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).10-20-2011
20110257224PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S,3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUO- ROBENZAMIDE - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetyl-choline receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).10-20-2011
20110263629AMIDES OF DIAZABICYCLOOCTANES AND USES THEREOF - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).10-27-2011
20120015983Synthesis and Novel Salt Forms of (R)-3-((E)-pyrrolidin-3-yl)vinyl)-5-tetrahydropyran-4-yloxy)pyridine - The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.01-19-2012
20130203860NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS - The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.08-08-2013
20140107163SYNTHESIS AND NOVEL SALT FORMS OF (R)-3-((E)-2-(PYRROLIDIN-3-YL)VINYL)-5-(TETRAHYDROPYRAN-4-YLOXY)PYRIDINE - The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.04-17-2014
20140163065PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S, 3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUOROBE- NZAMIDE - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).06-12-2014
20140288169NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS - The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for their use, and their pharmaceutical compositions.09-25-2014
20140288185NICOTINIC RECEPTOR NON-COMPETITIVE MODULATORS - The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.09-25-2014
20140315877NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS - The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.10-23-2014
20150031675DIAZABICYCLO[3.3.1]NONANES, METHODS OF SYNTHESIS, AND USES THEREOF - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).01-29-2015
20150105421PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S,3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUO- ROBENZAMIDE - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).04-16-2015

Patent applications by Daniel Yohannes, Winston-Salem, NC US

Daniel Yohannes, Stamford, NY US

Patent application numberDescriptionPublished
20150119253METHOD FOR INCREASING THE INTEGRATION LEVEL OF SUPERCONDUCTING ELECTRONICS CIRCUITS, AND A RESULTING CIRCUIT - A method for increasing the integration level of superconducting electronic circuits, comprising fabricating a series of planarized electrically conductive layers patterned into wiring, separated by planarized insulating layers, with vias communicating between the conductive layers. Contrary to the standard sequence of patterning from the bottom up, the pattern of vias in at least one insulating layer is formed prior to the pattern of wiring in the underlying conductive layer. This enables a reduction in the number of planarization steps, leading to a fabrication process which is faster and more reliable. In a preferred embodiment, the superconductor is niobium and the insulator is silicon dioxide. This method can provide 10 or more wiring layers in a complex integrated circuit, and is compatible with non-planarized circuits placed above the planarized wiring layers.04-30-2015
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