Patent application number | Description | Published |
20080206307 | BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer. | 08-28-2008 |
20080279898 | Biologically Degradable Compositions For Medical Applications - A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water. | 11-13-2008 |
20090036978 | Bioabsorbable coating with tunable hydrophobicity - The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases. | 02-05-2009 |
20090041845 | Implantable medical devices having thin absorbable coatings - Disclosed herein is a coating having a layer that includes a matrix phase and a dispersed phase substantially immiscible in the matrix phase and methods of using the same. | 02-12-2009 |
20090110713 | Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices - The present invention is directed to polymeric materials (e.g., coatings) comprising biodegradable copolymers and implantable devices (e.g., drug-delivery stents) formed of such materials. The biodegradable copolymers are derived from at least two relatively polar monomers and at least one relatively nonpolar monomer. Incorporation of at least one relatively nonpolar monomer into the copolymer improves controlled release of a hydrophobic drug from the polymeric material by increasing the copolymer's miscibility with and permeability to the hydrophobic drug. The polymeric materials can also contain at least one biocompatible moiety, at least one non-fouling moiety, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric materials are designed to improve the mechanical, physical and biological properties of implantable devices formed thereof. | 04-30-2009 |
20090111787 | Polymer blends for drug delivery stent matrix with improved thermal stability - Various embodiments of the present invention generally relate to a polymer blend composition used for coating a medical device that exhibits improved thermal stability. The invention also encompasses implantable medical devices coated the aforementioned coating. | 04-30-2009 |
20090238854 | PLASTICIZERS FOR COATING COMPOSITIONS - A biocompatible plasticizer useful for forming a coating composition with a biocompatible polymer is provided. The coating composition may also include a biobeneficial polymer and/or a bioactive agent. The coating composition can form a coating on an implantable device. The implantable device can be used to treat or prevent a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 09-24-2009 |
20090240325 | Implantable Medical Device Coatings With Improved Mechanical Stability - Implantable medical device coatings that have improved mechanical stability and medical devices coated with such coatings are disclosed. | 09-24-2009 |
20090299007 | BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES BASED ON POLYESTERS AND METHODS FOR FABRICATING THE SAME - Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid. | 12-03-2009 |
20090306120 | TERPOLYMERS CONTAINING LACTIDE AND GLYCOLIDE - The present invention provides an amorphous terpolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same. | 12-10-2009 |
20110001271 | Thermal Treatment Of An Implantable Medical Device - A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device. | 01-06-2011 |
20110003068 | Thermal Treatment Of An Implantable Medical Device - A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device. | 01-06-2011 |
20110008529 | Thermal Treatment Of An Implantable Medical Device - A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device. | 01-13-2011 |
20110027336 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid. | 02-03-2011 |
20110033517 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING HYDROPHILIC SUBSTANCES AND METHODS FOR FABRICATING THE SAME - A segmented polyurethane and an amphiphilic random or block copolymer are disclosed. The segmented polyurethane and the amphiphilic random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent. | 02-10-2011 |
20110117161 | BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer. | 05-19-2011 |
20110302677 | DETECTION AND CHARACTERIZATION OF LASER-INDUCED HEAT AFFECTED ZONES ON POLYMER BASED DEVICES - Detection and characterization of laser-induced heat affected zones on polymer based devices, such as polymeric stents, are described where Nano Thermal Analysis may be used with atomic force microscopy to obtain the thermal behavior of materials with a spatial resolution of under, e.g., 100 nm. Heat may be applied locally to the measured polymeric stem via a probe tip and the resulting thermal-mechanical response can be measured. | 12-08-2011 |
20120046640 | Coating Comprising An Elastin-Based Copolymer - The present invention is directed to medical devices including coatings. The coatings include a topcoat which includes a copolymer comprising a block of an elastin pentapeptide. The topcoat is over a layer of poly(vinyl alcohol) on a hydrophobic coating or over a porous coating comprising pores or depots that include a bioactive agent. | 02-23-2012 |
20120209371 | DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT - The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. | 08-16-2012 |
20120209372 | DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT - The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. | 08-16-2012 |
20120263759 | Coating Comprising An Elastin-Based Copolymer - A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. The copolymer may be used as a coating on a stent. Methods of using a stent coated with the copolymer are also provided. | 10-18-2012 |
20120328770 | Methods For Modulating The Release Rate Of A Drug-Coated Stent - Methods for modulating the release rate of a drug coated stent are disclosed. | 12-27-2012 |
20130087270 | Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS - Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. | 04-11-2013 |
20130142939 | Methods of Forming Coatings with a Crystalline or Partially Crystalline Drug for Implantable Medical Devices using Sonocrystallization - Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. | 06-06-2013 |
20130149430 | Methods of forming coatings with a crystalline or partially crystalline drug for implantable medical devices using supercritical fluid assisted sorption - Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. | 06-13-2013 |
20130149431 | Methods of Forming Coatings with a Crystalline or Partially Crystalline Drug for Implantable Medical Devices - Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. | 06-13-2013 |
20130178832 | DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT - The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. | 07-11-2013 |
20130230564 | Semi-Crystalline Composition For Coating - The present invention provides a coating comprising a semi-crystalline polymer on an implantable device and methods of making and using the same. | 09-05-2013 |
20130333193 | TEMPERATURE CONTROLLED CRIMPING - This disclosure describes a method for crimping a stent with a polymer coating onto a catheter for percutaneous transluminal coronary angioplasty or other intraluminal interventions. The method comprises crimping the stent onto a catheter when the polymer coating is at a target temperature other than ambient temperature. The polymer coating can optionally comprise drug(s). | 12-19-2013 |
20140004250 | Methods of treatment of polymeric coatings for control of agent release rates | 01-02-2014 |
20140031919 | Drug Eluting Implantable Medical Device With Hemocompatible And/Or Prohealing Topcoat - The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. | 01-30-2014 |